Catheterization and Cardiovascular Interventions最新文献

{"title":"Favorable Effects of Renal Denervation in Hypertension-Related Comorbidities. A Systematic Review and Meta-Analysis","authors":"Athanasios Makris,&nbsp;Stergios Soulaidopoulos,&nbsp;Marios Sagris,&nbsp;Konstantinos Platanias,&nbsp;Konstantinos Kyriakoulis,&nbsp;Dimitrios Konstantinidis,&nbsp;Fotis Tatakis,&nbsp;Georgios Gompos,&nbsp;Kyriakos Dimitriadis,&nbsp;Athanasios Kordalis,&nbsp;Dimitrios Tsiachris,&nbsp;Nikos Kafkas,&nbsp;Matthias Waliszewski,&nbsp;Konstantinos Tsioufis","doi":"10.1002/ccd.70600","DOIUrl":"10.1002/ccd.70600","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Renal denervation (RDN) according to the latest ESH guidelines can be considered as a treatment option for patients with resistant hypertension. However, excess sympathetic nervous system activity constitutes an underlying pathophysiological mechanism in many disorders other than arterial hypertension.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This systematic review and meta-analysis investigated the therapeutic effects of RDN beyond arterial hypertension.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic review and meta-analysis were conducted following PRISMA guidelines. Electronic databases (PubMed, Embase, Cochrane) were searched for studies assessing RDN effects in atrial fibrillation (AF) recurrence, obstructive sleep apnea (OSA), metabolic parameters, heart failure (HF) and diastolic heart function. Inclusion criteria encompassed randomized controlled trials and observational studies with relevant outcome measures. Effect sizes were pooled using a random-effects model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 16 studies comprising 818 patients were included. RDN was associated with a significant increase in freedom from AF when combined with pulmonary vein isolation (RR: 1.30, 95% CI: 1.04 to 1.61, <i>I</i>² = 5%), an improvement in OSA severity as measured by the apnea-hypopnea index (MD: −4.80, 95% CI: −12.60 to 3.01, <i>I</i>² = 39%), and decreased fasting blood glucose (MD: −10.04, 95% CI: −26.51 to 6.43, <i>I</i>² = 0%). Additionally, RDN led to improvements in left ventricular diastolic function in terms of E/e' reduction (MD: −1.51, 95% CI: −2.71 to −0.31, <i>I</i>² = 94%) and improved HF-related biomarkers, specifically NT pro-BNP (MD: −438.54, 95% CI: −1658.57 to 781.49, <i>I</i>² = 92%) and 6-min walking distance (MD: +64.58, 95% CI: 0.11 to 129.05, <i>I</i>² = 53%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This meta-analysis suggests that RDN exerts beneficial effects beyond hypertension, particularly in AF burden, OSA severity, metabolic parameters, and cardiac function. These findings support the broader role of RDN in autonomic regulation and cardiovascular health. Further large-scale trials are warranted to confirm these effects and refine patient selection criteria.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 7","pages":"2153-2161"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Frailty on Outcomes Following Mitral Transcatheter Edge-to-Edge Repair: A Propensity-Score Matched Analysis","authors":"Hritvik Jain,&nbsp;Nandan Patel,&nbsp;Jyoti Jain,&nbsp;Mushood Ahmed,&nbsp;Aman Goyal,&nbsp;Omar Baqal,&nbsp;Andrew M. Goldsweig","doi":"10.1002/ccd.70587","DOIUrl":"10.1002/ccd.70587","url":null,"abstract":"","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 7","pages":"2234-2239"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147625317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypotension During Chronic Total Occlusion Recanalization","authors":"Baotao Huang","doi":"10.1002/ccd.70593","DOIUrl":"10.1002/ccd.70593","url":null,"abstract":"<div>\u0000 \u0000 <p>Given the complexity of the procedure, chronic total occlusion (CTO) intervention is often associated with hemodynamic fluctuations. In such cases, it is necessary to ascertain potential causes involving the target vessel, the donor vessel, and non-coronary factors promptly. In addition, the relative hypoperfusion of the target vessel caused by immediate antegrade and retrograde competitive blood flow upon guidewire crossing and establishment of the procedural trajectory is also a problem worthy of consideration.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 7","pages":"2162-2167"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Celiac Culprit: Isolated Celiac Artery Stenosis Masquerading as Acute Coronary Syndrome With Marked Troponin Elevation: A Case Report","authors":"Yusuf Hosoglu,&nbsp;Ayse Hosoglu,&nbsp;Seyhmus Erkan Demircan,&nbsp;Faruk Ertas","doi":"10.1002/ccd.70608","DOIUrl":"10.1002/ccd.70608","url":null,"abstract":"<div>\u0000 \u0000 <p>Marked troponin elevation, indicative of myocardial injury, typically prompts evaluation for acute coronary syndrome (ACS). However, extra-cardiac pathologies can produce identical biomarker patterns, potentially diverting diagnostic reasoning and delaying definitive treatment. Isolated celiac artery stenosis is an uncommon cause of mesenteric ischemia that can mimic ACS. A 78-year-old woman presented with recurrent epigastric pain and significant troponin elevation (peak 2.492 ng/mL) despite non-obstructive coronary arteries. Selective abdominal angiography revealed isolated high-grade celiac artery stenosis with patent superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). The lesion was treated with a self-expanding stent, resulting in complete symptom resolution. Four years later, the patient re-presented with identical symptoms and troponin elevation. Imaging demonstrated focal in-stent restenosis, which was successfully treated with a balloon-expandable stent, achieving durable symptom relief. This case illustrates that isolated celiac artery stenosis can closely mimic ACS, producing marked troponin release in the absence of coronary obstruction. Recognition of this masquerading visceral ischemia requires careful attention to symptom patterns and a low threshold for visceral angiography. Durable outcomes can be achieved with endovascular therapy, even in cases of restenosis.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 7","pages":"2183-2185"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Terumo Azur Vascular Plug for Occlusion of the Patent Ductus Arteriosus in Premature Neonates—A First Clinical Application","authors":"Nicholas Fitzgerald,&nbsp;Alison Howell,&nbsp;Conal T. Morgan,&nbsp;Lee Benson,&nbsp;Rajiv R. Chaturvedi","doi":"10.1002/ccd.70606","DOIUrl":"10.1002/ccd.70606","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Transcatheter patent ductus arteriosus (PDA) occlusion outcomes in premature and low birth weight infants have improved with advances in procedural technique and availability of low-profile devices. We describe our clinical experience with the Azur Vascular Plug (Terumo Medical Corporation, NJ, USA) for PDA occlusion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To assess procedural success, safety and short-term outcomes of the Azur Vascular Plug for PDA occlusion in premature and low birth weight infants.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Single-center observational study of all preterm and low birth weight infants who underwent a transcatheter PDA occlusion procedure involving the Azur Vascular Plug between June 2024 and October 2025.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The Azur Plug was used in 13 infants. The median (range) procedural age was 44 days (17−93 days) and weight 1344 g (855–3900 g). Successful implantation with microcatheter deployment occurred in 12/13 infants. In 11 cases, the 8 mm Azure device was deployed. The ratio of the unconstrained device to the minimal PDA diameter ranged from 2:1 to 4:1 and decreased with experience. The minimal ductal length for deployment was 9.0 mm (lateral angiography). Mean (range) follow-up was 5.8 months (1.5–15.7 months). Complete ductal occlusion prior to 6-month follow-up occurred in 11/12 infants. No aortic obstruction, left pulmonary artery obstruction, or tricuspid valve injury was noted in follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The Azur Vascular Plug is a safe and effective option for PDA device occlusion in premature and low birth weight infants. The sizing limits in premature ducts are under evolution. The Azur device appears suitable for ducts with a minimal length of 9.0 mm and, conservatively, a diameter up to 5.0 mm.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 7","pages":"2223-2229"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147611618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Comparison of Vascular Access Closure Strategies in TAVI","authors":"Saif Zako,&nbsp;Kathrin Klein,&nbsp;Karin Alde,&nbsp;Christian Jung,&nbsp;Verena Veulemanns,&nbsp;Maximilian Scherner,&nbsp;Artur Lichtenberg,&nbsp;Malte Kelm,&nbsp;Tobias Zeus,&nbsp;Amin Polzin","doi":"10.1002/ccd.70586","DOIUrl":"10.1002/ccd.70586","url":null,"abstract":"&lt;p&gt;Transcatheter aortic valve implantation (TAVI) represents a well-established therapeutic approach for patients with severe symptomatic aortic valve stenosis. Access site-related vascular complications (VC) are the most frequent adverse events associated with TAVI [&lt;span&gt;1&lt;/span&gt;]. Various closure devices and combinations have been tested to reduce VC and bleeding. However, to date, the optimal strategy remains unclear. The ACCESS-TAVI randomized trial demonstrated that a combined suture- and plug-based vascular closure strategy can reduce VC compared to a suture-only approach [&lt;span&gt;2&lt;/span&gt;]. Nevertheless, real-world evidence is scarce. Here, we present a large real-world cohort comparing a combined suture-/plug-based versus a suture-only VCD strategy for vascular access closure following transfemoral TAVI. We conducted an analysis of the prospective Düsseldorf TAVI registry. A total of 2371 patients who underwent transfemoral TAVI at the University Hospital Düsseldorf between 2015 and 2024 were included. We compared two vascular closure device (VCD) strategies: a combined suture-/plug-based strategy (suture/plug group) using one ProGlide and one 8F Angio-Seal, versus a suture-based strategy (suture-only group) using two ProGlides. The endpoint was a composite of major or minor access site-related VC, as per VARC-3 criteria, during the index hospitalization.&lt;/p&gt;&lt;p&gt;The mean age of the cohort was 80.5 years. Arterial hypertension was present in 87.5%, and type 2 diabetes mellitus (T2D) in 30.2%. Pulmonary hypertension was observed in 57.2%, peripheral arterial disease in 25.2%, and COPD in 26.1%. Prior myocardial infarction and percutaneous coronary intervention were documented in 39.0% and 36.4% of patients, respectively. Nine hundred and forty-six patients were treated using the suture/plug strategy, and 1425 patients received suture-only closure. Baseline characteristics were largely comparable between groups. With the suture-only group showing significantly higher rates of peripheral artery disease (29.40% vs. 18.82%, &lt;i&gt;p&lt;/i&gt; &lt; 0.001) and arterial hypertension (90.74% vs. 82.66%, &lt;i&gt;p&lt;/i&gt; &lt; 0.001). Sheath size was larger in the suture-only group with a higher proportion of 16F sheaths (20.1% vs. 11.3%, &lt;i&gt;p&lt;/i&gt; &lt; 0.001). Patients in the suture/plug group had a higher rate of oral anticoagulation therapy (41.4% vs. 35.9%, &lt;i&gt;p&lt;/i&gt; = 0.01). No additional significant differences were observed between groups. To minimize baseline imbalances and potential temporal confounding that could bias the assessment of access-site-related VC, a propensity score matching (PSM) analysis including procedural year was conducted. After 1:1 nearest-neighbor matching, the groups demonstrated excellent covariate balance, allowing a more robust and unbiased comparison of outcomes while accounting for increasing operator experience and procedural advancements over time.&lt;/p&gt;&lt;p&gt;The combined endpoint, which includes major and minor VC related to the access s","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 7","pages":"2150-2152"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccd.70586","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 6","pages":"i-ix"},"PeriodicalIF":1.9,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148076520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Cutting and Retrieval of an Unraveled Embolization Coil With Rotational Atherectomy: A Case Report","authors":"Yusaku Nagatomo,&nbsp;Yasuhiro Nakano,&nbsp;Tetsuya Matoba,&nbsp;Yuichiro Hirata,&nbsp;Kohtaro Abe,&nbsp;Kenichiro Yamamura","doi":"10.1002/ccd.70482","DOIUrl":"10.1002/ccd.70482","url":null,"abstract":"<div>\u0000 \u0000 <p>Coil unraveling is a rare but potentially serious complication during transcatheter coil embolization. Once the braided coil has unraveled and loosened into wire filaments, percutaneous retrieval becomes extremely challenging. Although various percutaneous techniques have been described for retrieving migrated or unraveled coils, surgical removal or leaving the coil in situ may ultimately be required. We describe the first case of successful cutting and retrieval of an unraveled coil during coil embolization for a coronary pulmonary artery fistula (CPAF) using rotational atherectomy (RA). This novel troubleshooting technique may represent a valuable last-resort option in situations where conventional retrieval attempts are unsuccessful.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 5","pages":"1376-1379"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146014108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and Safety of the ETcath200 Robotic PCI System for Complex Coronary Lesions: A Prospective Single-Center Study","authors":"Jing Yang,&nbsp;Yuqi Fang,&nbsp;Yizhu Yan,&nbsp;Zijing Liu,&nbsp;Jing Xie,&nbsp;Ge Zhang,&nbsp;Zhicheng Zhang,&nbsp;Tienan Sun,&nbsp;Guangyao Zhai","doi":"10.1002/ccd.70488","DOIUrl":"10.1002/ccd.70488","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>International robotic-assisted PCI platforms such as CorPath 200 and CorPath GRX have demonstrated procedural safety and efficacy but are limited by the absence of real-time tactile feedback and cumbersome device exchange. The ETcath200, the first domestically developed robotic PCI system in China, introduces guidewire force-sensing to provide real-time visual resistance feedback that partially compensates for the lack of direct tactile sensation, along with streamlined device exchange and an intuitive joystick–roller interface.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study aimed to evaluate the feasibility, safety, and procedural performance of the ETcath200 system in patients with complex coronary lesions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this prospective, single-center, single-arm trial, 20 patients with AHA/ACC type B2 or C complex coronary lesions underwent PCI using the ETcath200 system. Technical success was defined as full robotic completion without any unplanned manual input (including partial manual assistance or manual conversion); clinical success as residual stenosis &lt; 30% with TIMI 3 flow and no in-hospital major adverse cardiac events (MACE). Patients were followed for 30 days.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All 20 patients (mean age 63.2 ± 12.0 years; 80% male) had unstable angina and complex coronary anatomy (79.2% type C lesions; 50% bifurcation, 65% diffuse). Most procedures were performed via radial access (80%), and the majority utilized drug-eluting stents (65%). Technical success was achieved in 16 cases (80%), while four cases (20%) required manual conversion due to severe tortuosity or calcification (<i>n</i> = 3) or guidewire-induced dissection (<i>n</i> = 1; managed successfully). All patients achieved clinical success; no device failures, MACE, or serious adverse events occurred at 30 days. Mean procedure duration was 61.0 ± 23.3 min; radiation dose was 0.07 ± 0.04 mSv.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The ETcath200 robotic PCI system demonstrated feasibility, safety, and reliable performance in complex coronary lesions, achieving high clinical success and excellent short-term outcomes. Manual conversion was required only in anatomically challenging cases. These data support further multicenter evaluation of ETcath200 in complex coronary interventions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 5","pages":"1393-1402"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13043798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146069614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OCT-Derived Virtual Fractional Flow Reserve Associated With 1-Year Outcomes After PCI in ACS Patients","authors":"Qianhang Xia,&nbsp;Shuangya Yang,&nbsp;Li Pan,&nbsp;Xi Wang,&nbsp;Chancui Deng,&nbsp;Ning Gu,&nbsp;Youcheng Shen,&nbsp;Jin Shen,&nbsp;Zhenglong Wang,&nbsp;Bei Shi,&nbsp;Ranzun Zhao","doi":"10.1002/ccd.70458","DOIUrl":"10.1002/ccd.70458","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Despite PCI, many acute coronary syndrome (ACS) patients experience major adverse cardiovascular events (MACE). Angiography is limited, and fractional flow reserve (FFR) is restricted by cost and specialized resource requirements. Optical coherence tomography (OCT)-derived FFR (OFR) allows functional assessment without hyperemia, but its prognostic role after PCI is unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To investigate the association between post-PCI OFR and 1-year target vessel-related MACE in ACS patients and to develop machine learning-based models to explore risk stratification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This single-center retrospective study included 719 ACS patients undergoing OCT-guided PCI at the Affiliated Hospital of Zunyi Medical University (May 2022 to December 2023). The primary endpoint was target vessel-related MACE (cardiac death, revascularization, myocardial infarction, or angina rehospitalization). Imaging features were selected by LASSO and Boruta, and machine learning–based classification models were built with XGBoost, random forest, support vector machine, logistic regression, and light gradient boosting. Performance was assessed using ROC curves and feature importance via GINI index.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 5","pages":"1324-1332"},"PeriodicalIF":1.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}