{"title":"Rhabdomyolysis Complicated by Acute Myocardial Infarction: A Case Report","authors":"Liran Zhang, Ziya Zhang, Yongmei Yu, Xiangyu Han","doi":"10.1002/ccd.70430","DOIUrl":"10.1002/ccd.70430","url":null,"abstract":"<div>\u0000 \u0000 <p>A 27-year-old male patient presented with bilateral lower limb pain and dark brown urine after intense exercise, which lasted half a day. He had no history of cardiac diseases. On admission, abnormal creatine kinase levels and urine tests suggested rhabdomyolysis and electrocardiogram (ECG) was unremarkable. During treatment, the patient developed severe chest pain, sweating, nausea, and vomiting. ECG indicated ST-T elevation in the V2, V3, V4, and V5 leads. Combined with ECG findings, elevated myocardial enzymes suggested acute myocardial infarction (AMI). Coronary angiography revealed a severe stenosis in the proximal segment of left anterior descending branch (pLAD), just before the origin of the first diagonal branch (D1). Optical coherence tomography (OCT) indicated a significant amount of mixed thrombus at the lesion site. After balloon dilation, repeated thrombus aspiration, and in-situ thrombolysis, the thrombus size decreased, blood flow improved, and stent placement was deferred. The patient received intensified antiplatelet therapy. After 1 week, coronary angiography showed no blockage, and the patient was discharged after stabilization. No significant chest pain was observed during follow-up.</p></div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"845-852"},"PeriodicalIF":1.9,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronary Artery Perforation During Percutaneous Coronary Intervention in a Myocardial Bridge: Case Report and Management Considerations","authors":"Parminder Sharma, Arghadip Bose, Rahul Nema, Parag Barwad","doi":"10.1002/ccd.70429","DOIUrl":"10.1002/ccd.70429","url":null,"abstract":"<div>\u0000 \u0000 <p>Coronary artery perforation (CAP) is a rare but potentially catastrophic complication of percutaneous coronary intervention (PCI), most frequently resulting from guidewire exit, balloon or stent deployment, or atherectomy. We report the case of a 77-year-old male with triple vessel disease who developed an Ellis class III CAP during staged PCI to the left anterior descending artery (LAD). The perforation occurred secondary to prolonged balloon inflation across a myocardial bridge, with contrast extravasation into the left ventricle producing severe angina via a coronary steal phenomenon, though without hemodynamic compromise or pericardial effusion. Initial balloon tamponade failed to seal the lesion, necessitating the deployment of a covered stent, which resulted in successful vessel sealing and complete symptom resolution. This case highlights the challenges of managing CAP in intramyocardial coronary segments and emphasizes covered stenting as an effective therapeutic option when conservative approaches fail.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"864-867"},"PeriodicalIF":1.9,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145728077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Srilakshmi M. Adhyapak, Prahlad G. Menon, Sneha George, Kiron Varghese
{"title":"Impact of Individual Culprit Coronary Arteries Revascularized by Primary PCI on Clinical Outcomes","authors":"Srilakshmi M. Adhyapak, Prahlad G. Menon, Sneha George, Kiron Varghese","doi":"10.1002/ccd.70427","DOIUrl":"10.1002/ccd.70427","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Studies on outcomes of primary PCI have shown that among patients with STEMI, complete revascularization had better outcomes than culprit vessel PCI alone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Data on individual coronary artery PCI is rare. We wanted to see if individual coronary artery PCI had effect on outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patients who did not undergo PCI had worst outcomes in terms of mortality and cardiogenic shock. LAD interventions had best outcomes with lesser complication rates. OM interventions had the best safety profile. LCX interventions had more incidence of complications and mortality as compared to LAD and RCA interventions. LCX lesions also had a high SYNTAX score. Branch vessel interventions had an intermediate to high-risk profile.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>We found that the clinical outcomes were significantly related to the coronary artery revascularized.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"842-844"},"PeriodicalIF":1.9,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yue Hin Tang, Joyce Chung Yan Kan, Raymond Chi Yan Fung
{"title":"First in Human—Bioadaptor Stenting in Myocardial Bridging","authors":"Yue Hin Tang, Joyce Chung Yan Kan, Raymond Chi Yan Fung","doi":"10.1002/ccd.70413","DOIUrl":"10.1002/ccd.70413","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 <p>In current practice, stenting a myocardial bridging segment is known to be associated with dire consequences such as stent fracture and in-stent restenosis, thus it should best be avoided. However, sometimes stenting a bridging segment may be deemed necessary due to various reasons. We present a case in which an unintended dissection extended into a bridging segment, warranting stenting. We studied the effect of the bioadaptor stent, with its unique uncaging element, in such a segment using optical coherence tomography (OCT). Reangiogram 8 months after the index procedure showed a satisfactory result with no stent-related complications, while OCT showed preservation of bridging vasomotion as well as a positive remodeling effect in the stented bridging segment. Bioadaptor stenting in the myocardial bridging segment can provide scaffold support, preserve the bridging vasomotion, and bring about a positive remodeling effect. This finding may impact future practice on stenting strategies in myocardial bridging, should it be necessary; however, further studies are required to validate this concept and its applicability to other bridging cases.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"858-863"},"PeriodicalIF":1.9,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Nazmy, Ahmed Sobhy, Ahmed Elshahat, Ahmed Abdelaziz, Ebtsam Makhlouf, Amira Fahmy El-Nemr, Mohammed Sabri Hassanin, Karim Atta, Ahmed Yasser Shaban, Mahmoud Nazmy, Rajesh K. Kharbanda, Basel Abdelazeem, Mamas A. Mamas
{"title":"Cerebral Embolic Protection Devices for the Prevention of Stroke in Patients Undergoing Transcatheter Aortic Valve Implantation: An Updated Meta-Analysis of Randomized Controlled Trials","authors":"Ahmed Nazmy, Ahmed Sobhy, Ahmed Elshahat, Ahmed Abdelaziz, Ebtsam Makhlouf, Amira Fahmy El-Nemr, Mohammed Sabri Hassanin, Karim Atta, Ahmed Yasser Shaban, Mahmoud Nazmy, Rajesh K. Kharbanda, Basel Abdelazeem, Mamas A. Mamas","doi":"10.1002/ccd.70411","DOIUrl":"10.1002/ccd.70411","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 <p>Stroke remains one of the most devastating complications following transcatheter aortic valve implantation (TAVI). Although cerebral embolic protection devices (CEPDs) have emerged to mitigate patients' risks, their impact on stroke risk, as well as other clinical and neurocognitive outcomes after TAVI, remains uncertain. We aimed to assess whether CEPDs alleviate stroke risks and neurocognitive outcomes after TAVI. We systematically searched MEDLINE, Scopus, Web of Science (WOS), and the Cochrane CENTRAL from inception until May 2025. We included randomized controlled trials (RCTs) that assessed the effectiveness of CEPD compared to the control group (no CEPD) in adult patients (> 18 years) undergoing TAVI. The primary endpoint was the incidence of all-cause stroke. In contrast, the secondary endpoints included disabling stroke, systemic bleeding, transient ischemic attack (TIA), and major adverse cardiovascular and cerebrovascular events (MACCE). Additionally, we assessed neurological outcomes, including changes in the Montreal Cognitive Assessment (MoCA) score, the National Institutes of Health Stroke Scale (NIHSS) score, and the presence of new ischemic lesions. Nine RCTs comprising 11,696 patients were included in the final analysis. The use of CEPDs showed no statistical difference in reducing all-cause stroke compared to the control group (OR = 0.91, 95% CI [0.73–1.15], <i>p </i>= 0.44). Additionally, there was no significant difference in other studies' secondary outcomes, including disabling stroke, MACCE, systemic bleeding, or neurological outcomes, such as worsening NISSS, decline in MoCA score, and the presence of new ischemic lesions. The use of CEPD during TAVI showed no benefit in reducing the risks of all-cause stroke and other neurological outcomes studied.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"795-806"},"PeriodicalIF":1.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yousef M. Husseiny, Shrouk Ramadan, Abdelrahman El-Helbawy, Fahed Negmeldin, Ali Dway, Hamza A. Abdul-Hafez, Ahmed Youssef Hassan, Mohamed Wasim Soued, Reem Husseiny, Fouad Hanna
{"title":"Mechanical Thrombectomy Versus Conventional Anticoagulants Alone in Treatment of Pulmonary Embolism: A Systematic Review and Meta-Analysis","authors":"Yousef M. Husseiny, Shrouk Ramadan, Abdelrahman El-Helbawy, Fahed Negmeldin, Ali Dway, Hamza A. Abdul-Hafez, Ahmed Youssef Hassan, Mohamed Wasim Soued, Reem Husseiny, Fouad Hanna","doi":"10.1002/ccd.70412","DOIUrl":"10.1002/ccd.70412","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 <p>Pulmonary embolism (PE) is a life-threatening condition and a leading cause of sudden death. It occurs when a thrombus develops in the venous system and then dislodges to embolize into the pulmonary arteries, causing obstruction. The current mainstay of treatment is anticoagulation. Adjunct mechanical thrombectomy (MT) or pharmacological thrombolysis may be added, following a risk assessment, for intermediate to massive PE. However, physicians remain reluctant to adopt them as first-line treatment when comparing the benefits and risks to anticoagulation alone. This study aims to compare the safety and efficacy of MT with anticoagulation therapy alone in the treatment of intermediate to large-sized PE patients, focusing on hospital stay, ICU admission, morbidity, and mortality. Following PRISMA guidelines, a search was conducted on PubMed, Scopus, Web of Science, and Google Scholar for studies published from inception up to July 5, 2025. Studies were then screened based on predefined inclusion and exclusion criteria. The Newcastle−Ottawa Scale was used to assess the quality of evidence. Studies were required to report at least one of the following outcomes: mortality rate, hospital stay, overall complications, and ICU stay. Screening & data were extracted independently by eight co-authors, and a senior co-author resolved all conflicts. From a pool of 5661 studies, a total of six studies (1509 patients) were included. MT was associated with a trend toward lower all-cause mortality (OR = 0.5, 95% CI, 0.27 to 1.01; <i>p </i>= 0.05; <i>I</i><sup>2</sup> = 46%) and a significantly lower rate of ICU length of stay by 3.0 days than those in the anticoagulant therapy group (MD: − 3.01, 95% CI, −5.57 to −0.44, <i>p </i>= 0.02; <i>I</i><sup>2</sup> = 83%). No significant difference was found in overall complications and length of hospital stay between the MT and anticoagulant groups. However, MT was associated with lower rates of overall complications by 49% (OR = 0.51, 95% CI, 0.10 to 2.67, <i>p </i>= 0.43; <i>I</i><sup>2</sup> = 83%) and shorter hospital stays (MD: −0.76; 95% CI, −4.64 to 3.13, <i>p </i>= 0.70; <i>I</i><sup>2</sup> = 93%). MT showed greater efficacy in reducing mortality rates and ICU stay compared to intermediate to high-risk PE patients treated with conventional anticoagulant therapy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"767-779"},"PeriodicalIF":1.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145710462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergio López-Tejero, Eric Horlick, Abhinay Challa, Yee Sen Chan Wah Hak, Mark Osten, Lee Benson
{"title":"Dual Coarctation of the Aorta: An Uncommon Long-Term Complication of Interrupted Aortic Arch Requiring Double-Stenting","authors":"Sergio López-Tejero, Eric Horlick, Abhinay Challa, Yee Sen Chan Wah Hak, Mark Osten, Lee Benson","doi":"10.1002/ccd.70397","DOIUrl":"10.1002/ccd.70397","url":null,"abstract":"<div>\u0000 \u0000 <p>We report the case of a 56-year-old male who underwent an extra-anatomic bypass at the age of 25. He presented with poor BP control, and was found to have two stenotic lesions in the graft: one at the proximal and one at the distal anastomosis. It worked as a “double coarctation of the aorta,” which could be treated through a transcatheter approach.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"807-809"},"PeriodicalIF":1.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stent-Free PCI With OCT-Guided Drug-Coated Balloon Angioplasty for Calcified Coronary Stenosis After Kawasaki Disease","authors":"Shuangliang Ma, Zhongxiu Chen, Yong He, Minggang Zhou","doi":"10.1002/ccd.70432","DOIUrl":"10.1002/ccd.70432","url":null,"abstract":"<div>\u0000 \u0000 <p>Kawasaki disease (KD) may cause coronary aneurysms and calcified stenosis, posing challenges for percutaneous coronary intervention (PCI). The role of drug-coated balloons (DCB) in this context remains uncertain. We report a 25-year-old man with prior KD who developed 90% calcified stenosis at the inlet of a left anterior descending artery aneurysm. Optical coherence tomography (OCT) confirmed severe calcification. Predilatation with a cutting balloon followed by paclitaxel-coated balloon angioplasty achieved lumen enlargement without dissection. Six-month angiography and OCT showed a patent vessel with smooth healing, and the patient remained event-free during 4 years of follow-up under antiplatelet and lipid-lowering therapy. This case highlights that intravascular imaging-guided, stent-free PCI with DCB may offer a feasible revascularization approach for KD-related calcified coronary stenosis, although long-term efficacy requires further evaluation.</p></div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"853-857"},"PeriodicalIF":1.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transcatheter Closure for Prevention of Stroke in an Octogenarian Woman With Dual Left Atrial “Appendages”","authors":"Tao He, Cong Lu, Zhenni Zhang, Jie Zeng","doi":"10.1002/ccd.70415","DOIUrl":"10.1002/ccd.70415","url":null,"abstract":"<div>\u0000 \u0000 <p>Thrombosis-induced stroke represents one of the most serious complications of atrial fibrillation (AF), and the presence of spontaneous echo contrast (SEC) is a well-established echocardiographic predictor of pre-thrombotic states. An 82-year-old woman with AF presented with recurrent ischemic strokes despite oral anticoagulation therapy and was referred to our center for left atrial appendage closure (LAAO). Transesophageal echocardiography (TEE) demonstrated slow flow within the left atrial appendage along with a large atrial septal aneurysm (ASA) exhibiting prominent SEC. Following multidisciplinary evaluation, simultaneous percutaneous closure of both the LAA and the ASA/PFO was successfully performed. Postprocedural follow-up demonstrated no device-related thrombosis, peri-device leak, or further stroke events. This case underscores the potential benefit of combined LAA and ASA/PFO closure in high-risk AF patients with recurrent embolic events despite anticoagulation.</p></div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"818-823"},"PeriodicalIF":1.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mary Breige O'Donnell-Smith, Daniel S. Levi, Gentian Lluri, Jamil Aboulhosn
{"title":"Harmony Transcatheter Pulmonary Valve Housing Compression: Bench Testing and Case Report","authors":"Mary Breige O'Donnell-Smith, Daniel S. Levi, Gentian Lluri, Jamil Aboulhosn","doi":"10.1002/ccd.70382","DOIUrl":"10.1002/ccd.70382","url":null,"abstract":"<div>\u0000 \u0000 <p>Use of the Harmony valve within a failing surgical bioprosthesis has not been described to date, especially with respect to compression of the valve and valve housing when Harmony is used in smaller, non-compliant landing zones. Described is a case of a 45-year-old male with a history of congenital pulmonary valve stenosis who underwent surgical pulmonary valve placement with a 25-mm Biocor Epic bioprosthesis and developed pulmonary regurgitation. The patient underwent cardiac catheterization with high-pressure balloon valvuloplasty with intentional fracturing and resultant compression of the left anterior descending (LAD) coronary artery. Hence, a balloon-expandable valve platform was not implanted due to concern for coronary artery compression. A bench assessment with flow analysis was performed to determine the suitability of the Harmony valve in this setting using ex vivo hydrodynamic testing with circular and elliptical compressions of the Harmony valve. Patient-specific testing was performed with additional fixture sizes created and tested to better understand valve performance under differing levels of compression. The tested size range for TPV22 and TPV25 started at 19 mm and increased every 1 mm in diameter until the unconstrained valve housing was reached. After bench testing, the patient underwent implantation of Harmony TPV25 with excellent immediate and intermediate-term outcomes.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"107 3","pages":"810-817"},"PeriodicalIF":1.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}