Catheterization and Cardiovascular Interventions最新文献

{"title":"Machine Learning in Intravascular Ultrasound: Validating Automated Lesion Assessment for Complex Coronary Interventions.","authors":"Jason Galo, Abhishek Chaturvedi, Abdullah Al-Qaraghuli, Pablo M Rubio, Cheng Zhang, Yirga Kahsay, Beni Rai Verma, Kalyan R Chitturi, Gary S Mintz, Ron Waksman, Brian C Case, Hayder Hashim, Hector M Garcia-Garcia","doi":"10.1002/ccd.31458","DOIUrl":"https://doi.org/10.1002/ccd.31458","url":null,"abstract":"<p><strong>Background: </strong>Intravascular ultrasound (IVUS) is essential for assessing complex coronary lesions, but remains underutilized in part due to difficulties in image interpretation. The AVVIGO IVUS Automated Lesion Assessment (ALA) software, which uses machine learning (ML) for automatic segmentation, promises to simplify lesion assessment. This study evaluated the agreement in stent size selection between ALA, an independent core laboratory (CL), and an expert interventional cardiologist (IC) for complex lesions.</p><p><strong>Aims: </strong>The primary endpoint was the agreement in stent size selection, within 0.25 mm, of AVVIGO ALA automatic segmentation of Class I lesions against the gold-standard measurement by an independent CL analysis and against an expert IC, (H. H.). The secondary endpoint was to assess the relative differences between AVVIGO ALA and CL, AVVIGO ALA and IC, and CL and IC, in vessel and lumen areas.</p><p><strong>Methods: </strong>Patients with complex coronary lesions, including left main bifurcation, long, and severely calcified lesions, were retrospectively analyzed using IVUS with ALA. Stent size selection and area measurements by ALA were compared against a CL and IC using established sizing methods.</p><p><strong>Results: </strong>In 48 patients, ALA demonstrated high agreement with CL (92%-100%) and IC (91%-98.5%) in stent size selection across lesion subtypes using recommended sizing methods. Lumen-based sizing achieved higher agreement than vessel-based sizing, particularly in calcified lesions (100% vs. 87%). The variability in relative difference in measurements between ALA and CL was greater than IC and CL in distal vessel and lesion vessel areas. The relative difference in measurements between ALA and IC was greater in vessel-based sizing compared to lumen-based sizing in the distal reference marker.</p><p><strong>Conclusion: </strong>AVVIGO ALA demonstrated high agreement in stent size selection compared to a CL and expert IC. ML's ability to automate IVUS analysis may improve operator efficiency, reduce radiation exposure, and enhance the adoption of intravascular imaging in routine practice. It remains to be seen if it will impact of adoption of IVUS to guide complex PCI.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Continuation Versus Interruption of Oral Anticoagulation During TAVI on Health-Related Quality of Life.","authors":"Dirk Jan van Ginkel, Willem L Bor, Hugo M Aarts, Christophe Dubois, Ole De Backer, Maxim J P Rooijakkers, Liesbeth Rosseel, Leo Veenstra, Ronak Delewi, Jurriën M Ten Berg","doi":"10.1002/ccd.31457","DOIUrl":"https://doi.org/10.1002/ccd.31457","url":null,"abstract":"<p><strong>Background: </strong>One-third of patients undergoing TAVR have a concomitant indication for oral anticoagulation. The impact of continuation as compared to interruption of oral anticoagulation during TAVR on health-related quality of life is unknown.</p><p><strong>Aims: </strong>To investigate the impact of continuation as compared to interruption of oral anticoagulation on health-related quality of life.</p><p><strong>Methods: </strong>The POPular PAUSE TAVI (Periprocedural Continuation vs. Interruption of Oral Anticoagulant Drugs during Transcatheter Aortic Valve Implantation) trial was an international, open-label, randomized, clinical trial performed at 22 European sites. Health-related quality of life was assessed using the Kansas City Cardiomyopathy Questionnaire (KCCQ) and Short Form-12 (SF-12) before, and at 1 and 3 months after TAVR.</p><p><strong>Results: </strong>A total of 8 patients were included: 431 were assigned to continuation and 427 to interruption of oral anticoagulation. Before TAVR, the mean overall KCCQ summary score was 53.6 (±26.0). At 1 month, the mean change in KCCQ summary score as compared to baseline was +11.4 points (95% confidence interval [CI] 8.0-14.8) in the continuation group and +12.2 points (95% CI 8.8-15.6) in the interruption group (difference -0.7 points; 95% CI -4.6 to 3.1). At 3 months, the mean change was +11.0 points (95% CI 7.3-14.6) versus +13.8 points (95% CI 10.2-17.4), respectively (difference -2.8 points; 95% CI -7.1 to 1.5). Mean changes in SF-12 physical and mental component summary scores showed no differences between both groups at 1 and 3 months after TAVR.</p><p><strong>Conclusions: </strong>In patients undergoing TAVR with a concomitant indication for oral anticoagulation, continuation as compared to interruption of oral anticoagulation during TAVR did not significantly impact health-related quality of life up to 3 months after TAVR.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocolised Management of Acute Myocardial Infarction Complicated by Cardiogenic Shock in Australia-Initial Experience From a Hub-and-Spoke Model.","authors":"Brendan Backhouse, Fabien Dade, Jason E Bloom, Xiaoman Xiao, Kawa Haji, Yang Yang, Craig French, Dion Stub, Vinodh Nanjayya, Sidney Lo, Michael Chiang, Mir B Basir, William O'Neill, Samer Noaman, Omar Al-Mukhtar, David Kaye, Nicholas Cox, William Chan","doi":"10.1002/ccd.31462","DOIUrl":"https://doi.org/10.1002/ccd.31462","url":null,"abstract":"<p><strong>Background: </strong>Acute myocardial infarction complicated by cardiogenic shock (AMICS) confers short-term mortality of 40%-50%. Protocolised network management of AMICS patients as part of a hub-and-spoke model supported by upstream mechanical circulatory support (MCS) is gaining traction globally to treat AMICS.</p><p><strong>Method: </strong>We conducted a prospective multicenter study in Melbourne, Australia describing our 5-year experience utilizing a protocolised hub-and-spoke model of care for patients with AMICS supported by planned upstream use of Impella CP (Abiomed, Danvers, MA).</p><p><strong>Results: </strong>From December 2019 to August 2024, 31 patients were treated for AMICS with Impella MCS support. Median age was 60 years and 87% were males. ST-elevation myocardial infarction accounted for 84% of presentations, and 29% were complicated by cardiac arrest. The majority of patients treated were in SCAI-CSWG stage D (52%), and stage C (26%) shock. Upstream Impella prior to PCI occurred in 84% of patients. The 30-day survival rate was 74%. An adverse event occurred in 39% of patients. Device-related complications were due to hemolysis (32%) and arrhythmia (3%). Escalation of MCS support was required in five patients (16%). Multivariate analysis identified patients requiring transfer to the hub center prior to revascularisation as an independent predictor of mortality (OR 13.2 [1.34-129.3] p = 0.027).</p><p><strong>Conclusion: </strong>In this first protocolised hub-and-spoke model of care for AMICS supported by planned upstream use of Impella in Australia, 30-day survival was high compared to published historical rates. Patient and device-related complication rates were low. Expansion of the hub-and-spoke model for the treatment of AMICS appears warranted.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis.","authors":"Ahmed Ibrahim, Laila Shalabi, Sofian Zreigh, Shrouk Ramadan, Sohaila Mourad, Ghaith Eljadid, Mohammed Beshr, Ali Abdelaziz, Muhammed Elhadi, Pierre Sabouret, Mamas Mamas","doi":"10.1002/ccd.31461","DOIUrl":"https://doi.org/10.1002/ccd.31461","url":null,"abstract":"<p><strong>Background: </strong>Left atrial appendage occlusion (LAAO) is an alternative to chronic oral anticoagulation (OAT) for stroke prevention in nonvalvular atrial fibrillation (NVAF) patients with contraindications to OAT. Postprocedure antithrombotic therapy (ATT) is essential to reduce the risk of device-related thrombosis (DRT), but the optimal regimen remains uncertain.</p><p><strong>Aims: </strong>This study aims to compare the safety and efficacy of low-dose direct oral anticoagulants (DOACs) versus dual antiplatelet therapy (DAPT) following LAAO.</p><p><strong>Methods: </strong>A comprehensive search of PubMed, Scopus, Cochrane, and Web of Science was conducted in August 2024. Studies comparing low-dose DOACs and DAPT post-LAAO were included. The primary outcomes were a composite efficacy endpoint (DRT, strokes, and systemic embolism [SE]) and major bleeding events as the safety endpoint. Secondary outcomes included all bleeding events, all-cause mortality, and a composite of efficacy and safety endpoints.</p><p><strong>Results: </strong>Four studies with 727 patients were included. Low-dose DOACs were associated with lower rates of the primary composite efficacy endpoint compared to DAPT (OR = 0.36; 95% CI [0.16, 0.85], p = 0.01). No significant difference in major bleeding events was observed (OR = 0.36; 95% CI [0.11, 1.18]; p = 0.091; I² = 0%). Compared to DAPT, low-dose DOACs were also associated with lower rates of DRT events (OR = 0.36; 95% CI [0.16, 0.79], p = 0.011).</p><p><strong>Conclusion: </strong>Low-dose DOACs effectively reduce thromboembolic events post-LAAO without increasing bleeding risk. These findings support their use as a viable ATT option, but larger trials are needed to confirm optimal regimens.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Device Selection in Percutaneous Paravalvular Leak Closure: A Comparative Study of Different Transthoracic and Transesophageal Echocardiographic Techniques.","authors":"Meltem Tekin, Gamze Babur Güler, Mehmet Çiçek, İbrahim Halil Tanboğa, Piotr Pysz, Arda Güler, Ali Rıza Demir, Yusuf Efe, Sezgin Atmaca, Dilara Pay, Ali Kemal Kalkan, Mehmet Ertürk","doi":"10.1002/ccd.31448","DOIUrl":"https://doi.org/10.1002/ccd.31448","url":null,"abstract":"<p><strong>Background: </strong>Clinically significant paravalvular leak (PVL) may complicate both surgical and transcatheter valve implantation. Percutaneous PVL closure (PPVLC) is becoming an increasingly attractive alternative to redo surgery, with demonstrated lower mortality and morbidity rates. Echocardiographic techniques are crucial for accurate diagnosis, defect sizing, and determining the appropriate size of the sealing devices.</p><p><strong>Aims: </strong>There is no consensus on the optimal imaging modality for PVLs. We aimed to compare transthoracic and transesophageal echocardiographic measurements to accurately determine defect size and estimate device size.</p><p><strong>Methods: </strong>We reviewed hospital records to identify patients diagnosed with moderate to severe and severe PVL from 2018 to 2024. A total of 81 patients who underwent PPVLC were evaluated. Eight of these patients were excluded due to unsuccessful PPVLC, leaving 73 patients who were successfully treated. The defect size for all patients was evaluated using 2D transthoracic echocardiography (TTE), 2D transesophageal echocardiography (TEE), direct 3D TEE cropped volume rendering vena contracta (VC) measurement, and 3D TEE multiplanar reconstruction (3D TEE MPR).</p><p><strong>Results: </strong>Among the 73 patients, 42 underwent aortic PPVLC and 31 underwent mitral PPVLC. Proportional odds logistic regression analysis identified 3D TEE MPR measurement as the strongest predictor of device size accuracy, both overall and within the aortic/mitral subgroups. In the mitral subgroup, the predictive power of direct 3D TEE cropped volume rendering VC measurement and 3D TEE MPR measurement were similar. Furthermore, a cut-off value of 7 mm was identified for hemodynamically significant jets as measured by 3D methods.</p><p><strong>Conclusion: </strong>Our findings suggest that using 3D TEE MPR significantly improves the accuracy of device size selection in both mitral and aortic PVL. Additionally, direct 3D TEE cropped volume rendering VC measurement can serve as a viable alternative for patients with mitral PVL.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INtravaScular OptIcal Frequency Domain ImaGing EvaluaTion of the Femoropopliteal Lesion With JETSTREAM Atherectomy (INSIGHT JETSTREAM).","authors":"Koji Kuroda, Amane Kozuki, Kenzo Uzu, Takafumi Todoroki, Masamichi Iwasaki, Junichi Imanishi, Souichiro Yamashita, Wataru Fujimoto, Makoto Takemoto, Mayuka Masuda, Masanori Okuda","doi":"10.1002/ccd.31460","DOIUrl":"https://doi.org/10.1002/ccd.31460","url":null,"abstract":"<p><strong>Background: </strong>There have been no prior reports of detailed evaluations using intravascular imaging during Jetstream treatment.</p><p><strong>Aims: </strong>This study, therefore, aimed to investigate the effects of calcification characteristics and wire bias on lumen gain in Jetstream atherectomy using optical frequency domain imaging (OFDI).</p><p><strong>Methods: </strong>This study enrolled consecutive patients who underwent OFDI-guided Jetstream atherectomy with 1.85 mm, 2.4 mm blade down (BD), and 2.4 mm blade up (BU). Cross-sections were categorized into three groups based on OFDI findings before Jetstream atherectomy: fibrous plaques (FPs), calcified protrusions (CPs), and eruptive calcified nodules (ECNs).</p><p><strong>Results: </strong>Twenty-seven patients (36 limbs) were enrolled, and 1502 cross-sections were serially analyzed. There were 186 FPs, 753 CPs, and 563 ECNs. The acquired lumen gain after all atherectomy steps was significantly larger in the ECNs group than in the CPs and FPs groups. ECNs had the strongest effect on the variability in the lumen gain. In the effect of wire bias on the degree of debulking, a significant correlation was observed between wire distance and lumen gain in 1.85- and 2.4-mm BD atherectomy procedures. However, in the 2.4-mm BU procedure, no significant correlation was recorded.</p><p><strong>Conclusions: </strong>Jetstream atherectomy for ECNs can result in greater lumen gain. In the 1.85- and 2.4-mm BD atherectomy procedures, wire bias may be involved in lumen gain, whereas in the 2.4-mm BU procedure, lumen gain is obtained regardless of wire bias. In Jetstream atherectomy procedures, a detailed assessment using OFDI may contribute to predicting the degree of debulking.</p><p><strong>Trial registration: </strong>UMIN ID: UMIN000054588. https://center6.umin.ac.jp/cgi-bin/ctr/ctr_view_reg.cgi?recptno=R000061997.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial Infarction and All-Cause Mortality Following Percutaneous Coronary Intervention Versus Conservative Treatment of Chronic Total Occlusions: A West Denmark Heart Registry Study.","authors":"Marc Meller Søndergaard, Sanna Gunnarstein, Martin Kirk Christensen, Evald Høj Christiansen, Lisette Okkels Jensen, Karsten Tange Veien, Emil Nielsen Holck, Kristian Kragholm, Leif Thuesen, Ashkan Eftekhari","doi":"10.1002/ccd.31454","DOIUrl":"https://doi.org/10.1002/ccd.31454","url":null,"abstract":"<p><strong>Background: </strong>Chronic coronary total occlusions (CTO) represent a therapeutic challenge, and results of randomized clinical trials and observational studies comparing conservative treatment versus percutaneous coronary intervention (PCI) are underpowered.</p><p><strong>Aims: </strong>To assess myocardial infarction (MI) and all-cause mortality in consecutive patients with CTO lesions.</p><p><strong>Methods: </strong>Using data from the West Denmark Heart Registry, patients with chronic coronary syndrome and a 100% occluded vessel by invasive coronary angiography (ICA) were identified. Patients were stratified according to PCI within 90 days. Five-year risk of MI and all-cause mortality was calculated using cause-specific Cox-models and g-formula methods. Subsequently, models were stratified on sex, diabetes, estimated glomerular filtration rate above 60 mL/min, procedure before 2012, and history of cardiac surgery. The risk was calculated for patients who did not experience MI or death within 30 days of the initial ICA.</p><p><strong>Results: </strong>A total of 7675 patients were included in the study, of whom 3129 patients underwent PCI, and 4546 patients were treated conservatively. PCI- and conservatively treated patients had comparable risks of MI (13.1% [95% confidence interval [CI] 12.0%-14.3%] for patients who underwent PCI vs. 13.4% [95% CI 12.4%-13.4%] for patients who received conservative treatment). For all-cause mortality, results were 14.4% (95% CI 13.3%-15.5%) versus 18.9% (95% CI 17.8%-20.0%), respectively. Results were consistent across subgroups. However, CTO-PCI-treated patients with previous heart surgery were at higher risk of MI.</p><p><strong>Conclusions: </strong>Patients who underwent CTO-PCI had a comparable 5-year risk of MI and lower all-cause mortality as compared to conservatively treated patients.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do We Need to Perform Control Angiography in Patients Undergoing Percutaneous Coronary Intervention After Tirofiban Infusion?","authors":"Gülden Güven, İlyas Çetin, Şevval Kılıç, Şeyma Acaroğlu, Kartal Emre Aslanger, Mehmet Rasih Sonsöz","doi":"10.1002/ccd.31445","DOIUrl":"https://doi.org/10.1002/ccd.31445","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the effect of control imaging after intravenous (IV) tirofiban infusion on the clinical outcome of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>Patients who underwent PCI between June 2020 and October 2023 at our tertiary referral hospital and received tirofiban infusion were analyzed. Primary composite endpoint was the combination of cardiovascular death, myocardial infarction, cerebrovascular accident, or unplanned revascularization during follow-up.</p><p><strong>Results: </strong>A total of 217 patients (22.6% female, mean age: 58 ± 13 years) with ACS who received IV tirofiban therapy after PCI were compared in three groups: Patients without additional procedure (n = 131), patients undergoing control coronary angiography after index PCI (n = 43), and patients undergoing additional PCI after index PCI (n = 43). The most common reason for clinical intervention was STEMI (65.9%). After approximately 1 year of follow-up, primary composite endpoint of cardiac death, myocardial infarction, cerebrovascular accident, or unplanned revascularization was similar in all groups (30 [22.9%] vs. 15 [35%] vs. 12 [28%], p = 0.290).</p><p><strong>Conclusion: </strong>Repeat coronary angiography and additional PCI after tirofiban infusion in patients undergoing index PCI were associated with similar cardiovascular outcomes at 1-year follow-up compared with no repeat coronary angiography.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Stent Placement in Ostial Coronary Lesions With the Floating Balloon Technique: The OSTIAL (Optimizing Stent In Aorto-Ostial Lesion) Pivotal Study","authors":"Franck Digne,&nbsp;Arthur Darmon,&nbsp;Salim Belguidoum,&nbsp;Mohammed Nejjari,&nbsp;Jacques Feignoux","doi":"10.1002/ccd.31449","DOIUrl":"10.1002/ccd.31449","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Managing aorto-ostial coronary lesions during percutaneous coronary interventions (PCI) presents significant challenges due to complex anatomy, catheter instability, and risks of stent misplacement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>The OSTIAL pivotal study aimed to assess the feasibility and precision of the floating balloon technique for optimizing stent placement in aorto-ostial lesions (AOL), with post-procedural coronary computed tomography angiography (CCTA) used to evaluate stent positioning.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective, dual-center observational study included 12 patients undergoing PCI for AOL using the floating balloon technique. The technique stabilizes the guiding catheter by positioning a balloon in the aorta, thereby defining the aorto-ostial landing zone (AOLZ) for precise stent placement. Post-procedural CCTA were systematically performed to assess the positioning of the stent. The primary outcome was technical success including optimal stent placement within the AOLZ and proximal anatomy-dependent geographic miss.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The primary outcome was achieved in 83% of cases, with 66% showing complete AOLZ coverage and 17% classified as a proximal anatomy-dependent geographic miss. Proximal procedure-dependent geographic miss occurred in only 17% of cases, with limited stent protrusion into the aorta (2.3 and 2.9 mm).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The floating balloon technique demonstrated feasibility and precision in optimizing stent placement in AOL, as assessed by CCTA. It offers a promising, cost-effective, and practical alternative to other techniques. Larger studies are required to confirm its efficacy and long-term benefits.</p>\u0000 </section>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"105 5","pages":"1269-1277"},"PeriodicalIF":2.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Application of Combined Cutting Balloon and Rotational Atherectomy and Intravascular Lithotripsy in Old Degenerated Saphenous Venous Graft","authors":"Ayman Helal,&nbsp;Aaysha Cader,&nbsp;Simon Hetherington,&nbsp;Kai Hogrefe","doi":"10.1002/ccd.31455","DOIUrl":"10.1002/ccd.31455","url":null,"abstract":"<div>\u0000 \u0000 <p>Saphenous venous grafts (SVGs) are prone to progressive degeneration, leading to complex calcified lesions, which present a therapeutic challenge during percutaneous coronary interventions (PCI). Calcium modification techniques such as cutting balloons, intravascular lithotripsy (IVL), and rotational atherectomy have been employed in native coronary arteries; however, the use of rotational atherectomy in SVGs is controversial. This case report presents a novel approach where calcium modification techniques were successfully used to treat calcified stenosis in 30 years old SVG. The case demonstrates safe and effective use of rotational atherectomy in an SVG, possibly making it the first documented application of this technique in such a context. The report explores the rationale, procedural details, and potential risks of this approach, supported by a review of the existing literature.</p>\u0000 </div>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":"105 5","pages":"1260-1264"},"PeriodicalIF":2.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}