Gülden Güven, İlyas Çetin, Şevval Kılıç, Şeyma Acaroğlu, Kartal Emre Aslanger, Mehmet Rasih Sonsöz
{"title":"Do We Need to Perform Control Angiography in Patients Undergoing Percutaneous Coronary Intervention After Tirofiban Infusion?","authors":"Gülden Güven, İlyas Çetin, Şevval Kılıç, Şeyma Acaroğlu, Kartal Emre Aslanger, Mehmet Rasih Sonsöz","doi":"10.1002/ccd.31445","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the effect of control imaging after intravenous (IV) tirofiban infusion on the clinical outcome of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>Patients who underwent PCI between June 2020 and October 2023 at our tertiary referral hospital and received tirofiban infusion were analyzed. Primary composite endpoint was the combination of cardiovascular death, myocardial infarction, cerebrovascular accident, or unplanned revascularization during follow-up.</p><p><strong>Results: </strong>A total of 217 patients (22.6% female, mean age: 58 ± 13 years) with ACS who received IV tirofiban therapy after PCI were compared in three groups: Patients without additional procedure (n = 131), patients undergoing control coronary angiography after index PCI (n = 43), and patients undergoing additional PCI after index PCI (n = 43). The most common reason for clinical intervention was STEMI (65.9%). After approximately 1 year of follow-up, primary composite endpoint of cardiac death, myocardial infarction, cerebrovascular accident, or unplanned revascularization was similar in all groups (30 [22.9%] vs. 15 [35%] vs. 12 [28%], p = 0.290).</p><p><strong>Conclusion: </strong>Repeat coronary angiography and additional PCI after tirofiban infusion in patients undergoing index PCI were associated with similar cardiovascular outcomes at 1-year follow-up compared with no repeat coronary angiography.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Catheterization and Cardiovascular Interventions","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/ccd.31445","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The aim of this study was to investigate the effect of control imaging after intravenous (IV) tirofiban infusion on the clinical outcome of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI).
Methods: Patients who underwent PCI between June 2020 and October 2023 at our tertiary referral hospital and received tirofiban infusion were analyzed. Primary composite endpoint was the combination of cardiovascular death, myocardial infarction, cerebrovascular accident, or unplanned revascularization during follow-up.
Results: A total of 217 patients (22.6% female, mean age: 58 ± 13 years) with ACS who received IV tirofiban therapy after PCI were compared in three groups: Patients without additional procedure (n = 131), patients undergoing control coronary angiography after index PCI (n = 43), and patients undergoing additional PCI after index PCI (n = 43). The most common reason for clinical intervention was STEMI (65.9%). After approximately 1 year of follow-up, primary composite endpoint of cardiac death, myocardial infarction, cerebrovascular accident, or unplanned revascularization was similar in all groups (30 [22.9%] vs. 15 [35%] vs. 12 [28%], p = 0.290).
Conclusion: Repeat coronary angiography and additional PCI after tirofiban infusion in patients undergoing index PCI were associated with similar cardiovascular outcomes at 1-year follow-up compared with no repeat coronary angiography.
期刊介绍:
Catheterization and Cardiovascular Interventions is an international journal covering the broad field of cardiovascular diseases. Subject material includes basic and clinical information that is derived from or related to invasive and interventional coronary or peripheral vascular techniques. The journal focuses on material that will be of immediate practical value to physicians providing patient care in the clinical laboratory setting. To accomplish this, the journal publishes Preliminary Reports and Work In Progress articles that complement the traditional Original Studies, Case Reports, and Comprehensive Reviews. Perspective and insight concerning controversial subjects and evolving technologies are provided regularly through Editorial Commentaries furnished by members of the Editorial Board and other experts. Articles are subject to double-blind peer review and complete editorial evaluation prior to any decision regarding acceptability.