Case Reports in Ophthalmology最新文献

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From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female. 从脱发到失明:一名年轻女性的米诺地尔相关性视网膜病变。
IF 0.5
Case Reports in Ophthalmology Pub Date : 2024-03-18 eCollection Date: 2024-01-01 DOI: 10.1159/000537911
Lauren Pickel, Patrick Xiang Ji, Amr Abdelazim, Nirojini Sivachandran
{"title":"From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female.","authors":"Lauren Pickel, Patrick Xiang Ji, Amr Abdelazim, Nirojini Sivachandran","doi":"10.1159/000537911","DOIUrl":"10.1159/000537911","url":null,"abstract":"<p><strong>Introduction: </strong>Central retinal vein occlusion (CRVO) is a common retinal vascular disorder that is most often seen in older adults and individuals with vascular risk factors.</p><p><strong>Case presentation: </strong>We report a case of CRVO with cystoid macular edema (CME) in a young, otherwise healthy patient taking minoxidil for hair loss. The patient had no known vascular risk factors, and a comprehensive coagulability workup was negative. The CRVO with CME resolved without intervention upon cessation of minoxidil.</p><p><strong>Conclusion: </strong>Possible mechanisms for minoxidil-associated retinal vascular disorders are explored. Thorough medication histories and the consideration of possible adverse drug events in patients without traditional risk factors are recommended.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"220-224"},"PeriodicalIF":0.5,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10948167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140157588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GNB1-Related Rod-Cone Dystrophy: A Case Report. 与 GNB1 相关的杆-锥体营养不良症:病例报告
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-18 eCollection Date: 2024-01-01 DOI: 10.1159/000537997
Giovanni Marco Conti, Francesca Cancellieri, Mathieu Quinodoz, Karolina Kaminska, Veronika Vaclavik, Carlo Rivolta, Hoai Viet Tran
{"title":"GNB1-Related Rod-Cone Dystrophy: A Case Report.","authors":"Giovanni Marco Conti, Francesca Cancellieri, Mathieu Quinodoz, Karolina Kaminska, Veronika Vaclavik, Carlo Rivolta, Hoai Viet Tran","doi":"10.1159/000537997","DOIUrl":"10.1159/000537997","url":null,"abstract":"<p><strong>Introduction: </strong>The <i>GNB1</i> (guanine nucleotide-binding protein, β1) gene encodes for the ubiquitous β1 subunit of heterotrimeric G proteins, which are associated with G-protein-coupled receptors (GPCRs). <i>GNB1</i> mutations cause a neurodevelopmental disorder characterized by a broad clinical spectrum. A novel variant has recently been confirmed in a case of rod-cone dystrophy.</p><p><strong>Case presentation: </strong>We describe the second confirmed case of a classical rod-cone dystrophy associated with a mutation located in exon 6 of <i>GNB1</i> [NM_002074.5:c.217G>C, p.(Ala73Pro)] in a 56-year-old patient also presenting mild intellectual disability, attention deficit/hyperactivity disorder, and truncal obesity.</p><p><strong>Conclusion: </strong>This paper confirms the role of <i>GNB1</i> in the pathogenesis of a classic rod-cone dystrophy and highlights the importance of including this gene in the genetic analysis panel for inherited retinal diseases.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"230-237"},"PeriodicalIF":0.4,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10948171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140157589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Melanocytic Nevus of the Superior Conjunctival Fornix: A Case Report. 上结膜穹窿的黑素细胞痣:病例报告。
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-18 eCollection Date: 2024-01-01 DOI: 10.1159/000537876
Modupe O Adetunji, Thomas J Cummings, Miguel A Materin, Arpita S Maniar
{"title":"Melanocytic Nevus of the Superior Conjunctival Fornix: A Case Report.","authors":"Modupe O Adetunji, Thomas J Cummings, Miguel A Materin, Arpita S Maniar","doi":"10.1159/000537876","DOIUrl":"10.1159/000537876","url":null,"abstract":"<p><strong>Introduction: </strong>Conjunctival nevi are benign tumors that are commonly located at the nasal or temporal limbus and rarely in the fornix or tarsus. We report a case of a patient presenting with a solitary compound cystic nevus of the conjunctival fornix in the background of bilateral complexion-associated melanosis.</p><p><strong>Case presentation: </strong>A 71-year-old African-American female was referred for evaluation of an incidentally noted melanocytic lesion of the right conjunctival fornix. The patient underwent an excisional biopsy, revealing histological features consistent with a compound cystic nevus.</p><p><strong>Conclusion: </strong>This finding is noteworthy due to the rarity of conjunctival nevi originating in the fornix. The case underscores the importance of excisional biopsy in evaluating conjunctival forniceal melanocytic lesions to exclude malignant melanoma, a critical consideration for prognosis.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"225-229"},"PeriodicalIF":0.4,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10948165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140157590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combining Surgery, Radiotherapy, and Topical Chemotherapy to Prevent Primary Orbital Exenteration for Atypical Caruncular Melanoma: A Case Report. 结合手术、放疗和局部化疗,防止非典型眼眶黑色素瘤的原发性眼眶扩张:病例报告。
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-15 eCollection Date: 2024-01-01 DOI: 10.1159/000536590
Cédric De Landsheer, Valentien Merlevede, Celine Jacobs, Jo Van Dorpe, Julie De Zaeytijd, Virginie G S Ninclaus, Dimitri Roels
{"title":"Combining Surgery, Radiotherapy, and Topical Chemotherapy to Prevent Primary Orbital Exenteration for Atypical Caruncular Melanoma: A Case Report.","authors":"Cédric De Landsheer, Valentien Merlevede, Celine Jacobs, Jo Van Dorpe, Julie De Zaeytijd, Virginie G S Ninclaus, Dimitri Roels","doi":"10.1159/000536590","DOIUrl":"10.1159/000536590","url":null,"abstract":"<p><strong>Introduction: </strong>This case report demonstrates the possibility of successful eye and vision-sparing therapy for caruncular melanoma.</p><p><strong>Case presentation: </strong>We present an atypical presentation of a caruncular melanoma. After excisional biopsy, residual flat conjunctival melanosis resolved using topical chemotherapy (5-fluorouracil), which was well tolerated. Relapse of the melanoma was treated with external beam radiotherapy, but the tumor grew despite treatment. Eighteen months after complete excision of the relapsed melanoma, the patient remains tumor-free while the eye and its function remain preserved.</p><p><strong>Conclusion: </strong>This case report suggests that aggressive eye-sparing therapy for caruncular melanoma combining surgery, adjuvant topical chemotherapy, and external beam radiotherapy, can be an alternative for primary orbital exenteration.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"212-219"},"PeriodicalIF":0.4,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10942793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140142827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
White Dot Syndromes: Report of Three Cases. 白点综合征:三个病例的报告
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-14 eCollection Date: 2024-01-01 DOI: 10.1159/000536336
Leire Olazaran, Ana Jiménez, Pablo González de Los Mártires, Gonzalo Guerrero, Nerea Gangoitia, Iñigo Salmeron, Ane Galarza, Ana Sofía Argüelles, Beatriz Elso, Irene Reyzabal, Esther Compains, Henar Heras, Santiago López
{"title":"White Dot Syndromes: Report of Three Cases.","authors":"Leire Olazaran, Ana Jiménez, Pablo González de Los Mártires, Gonzalo Guerrero, Nerea Gangoitia, Iñigo Salmeron, Ane Galarza, Ana Sofía Argüelles, Beatriz Elso, Irene Reyzabal, Esther Compains, Henar Heras, Santiago López","doi":"10.1159/000536336","DOIUrl":"10.1159/000536336","url":null,"abstract":"<p><strong>Introduction: </strong>The term white dot syndromes has been used to refer conditions that differ in their morphology and prognosis. We report three cases of different pathologies encompassed within the white dot syndromes.</p><p><strong>Case presentations: </strong>Case 1: A 26-year-old female presented with scotoma in her right eye. Fundus examination revealed multiple white dots that demonstrated early hyperfluorescence with late staining on FA. OCT showed discontinuities in inner segment-outer segment junction associated with columnar-shaped outer retinal hyperreflective bands. AF revealed multiple hyperautofluorescent dots around the posterior pole, compatible with multiple evanescent white dot syndrome. The symptoms improved without treatment. Case 2: A 16-year-old male presented with retinal lesions compatible with punctate inner choroidopathy in his right eye. OCT showed lesion in the outer retinal layer. FAF revealed parafoveal hypoautofluorescent dots with early hyperfluorescence and late staining on FFA. After oral corticotherapy, they progress to atrophic scars. Case 3: A 65-year-old male presented with scotoma and decreased vision in his right eye. OCT showed hyperreflectivity in the outer layer that progresses to a large atrophic plaque with foveal affectation. FAF demonstrated hyperautofluorescent placoid lesion occupying macular area, compatible with acute posterior multifocal placoid pigment epitheliopathy. Retinal lesions improved with systemic corticosteroids.</p><p><strong>Conclusion: </strong>The FAF pattern helps know the distribution of the lesions. It represents a noninvasive method that has been shown to be useful in the diagnosis and monitoring of white dot syndromes.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"202-211"},"PeriodicalIF":0.4,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140130801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capsular Block Syndrome after an Intravitreal Injection of Ranibizumab: A Case Report. 玻璃体内注射雷珠单抗后的囊膜阻滞综合征:病例报告。
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-12 eCollection Date: 2024-01-01 DOI: 10.1159/000537755
Jae Suk Kim
{"title":"Capsular Block Syndrome after an Intravitreal Injection of Ranibizumab: A Case Report.","authors":"Jae Suk Kim","doi":"10.1159/000537755","DOIUrl":"10.1159/000537755","url":null,"abstract":"<p><strong>Introduction: </strong>We present a case of capsular block syndrome that occurred after intravitreal injection of ranibizumab in a patient with age-related macular degeneration, which has not been reported in the literature.</p><p><strong>Case presentation: </strong>A 78-year-old male presented with decreased visual acuity in the right eye. Slit-lamp examination findings were unremarkable; however, AMD was diagnosed based on fundus examination, fluorescein angiography, and optical coherence tomography (OCT). Subsequently, the patient was administered an intravitreal injection of ranibizumab. A slit-lamp examination revealed residual cortical material, numerous inflammatory cells, and posterior capsular distension 1 week after the injection. OCT showed an adhesion of the intraocular lens to the continuous curvilinear capsulorhexis site. The patient's vision improved following Nd:YAG laser posterior capsulotomy.</p><p><strong>Conclusion: </strong>Meticulous cortical removal is crucial during phacoemulsification to prevent capsular block syndrome. In patients with a history of cataract surgery, verifying the absence of residual cortical material before administering an intravitreal injection of ranibizumab is important.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"196-201"},"PeriodicalIF":0.4,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10932552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vogt-Koyanagi-Harada-Like Disease with Loss of Visual Acuity due to Sunitinib Treatment Restored after Switch in Therapy: A Case Report. 因舒尼替尼治疗导致视力丧失的 Vogt-Koyanagi-Harada 类疾病在转换疗法后恢复了视力:病例报告。
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-07 eCollection Date: 2024-01-01 DOI: 10.1159/000536572
Mechteld C S van Olden, Yvonne de Jong-Hesse, Tessa Vollebregt, Stefanie de Groot, Saskia A C Luelmo, Marina Marinkovic
{"title":"Vogt-Koyanagi-Harada-Like Disease with Loss of Visual Acuity due to Sunitinib Treatment Restored after Switch in Therapy: A Case Report.","authors":"Mechteld C S van Olden, Yvonne de Jong-Hesse, Tessa Vollebregt, Stefanie de Groot, Saskia A C Luelmo, Marina Marinkovic","doi":"10.1159/000536572","DOIUrl":"10.1159/000536572","url":null,"abstract":"<p><strong>Introduction: </strong>In this paper, we report a case of visual impairment during treatment with sunitinib in a patient with metastatic renal cell carcinoma.</p><p><strong>Methods: </strong>Retrospective chart review was used.</p><p><strong>Case presentation: </strong>We describe a 74-year-old male with metastatic renal cell carcinoma who was treated with sunitinib and experienced severe loss of visual acuity due to serous retinal detachment and intraretinal fluid. Upon discontinuation of sunitinib, the retinal fluid resolved, and visual acuity was restored.</p><p><strong>Conclusion: </strong>Serous retinal detachment has been described as a side effect of sunitinib use. Discontinuing sunitinib promptly resolved the subretinal fluid collections and restored vision.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"184-188"},"PeriodicalIF":0.4,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140058738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Horizontal Gaze Palsy and Ipsilateral Facial Nerve Palsy in Older Patient as Initial Manifestation of Very Late-Onset Multiple Sclerosis Successfully Treated with Oral Corticosteroids: A Case Report. 口服皮质类固醇治疗成功的老年晚发型多发性硬化症初期表现--水平凝视麻痹和同侧面神经麻痹:病例报告。
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-05 eCollection Date: 2024-01-01 DOI: 10.1159/000536639
Tjoa Debby Angela Tjoanda, Antonia Kartika, Dianita Veulina Ginting, Rusti Hanindya Sari, Prettyla Yollamanda
{"title":"Horizontal Gaze Palsy and Ipsilateral Facial Nerve Palsy in Older Patient as Initial Manifestation of Very Late-Onset Multiple Sclerosis Successfully Treated with Oral Corticosteroids: A Case Report.","authors":"Tjoa Debby Angela Tjoanda, Antonia Kartika, Dianita Veulina Ginting, Rusti Hanindya Sari, Prettyla Yollamanda","doi":"10.1159/000536639","DOIUrl":"10.1159/000536639","url":null,"abstract":"<p><strong>Introduction: </strong>Multiple sclerosis (MS) is a demyelinating condition of the central nervous system (CNS) that primarily affects young adults. Very late-onset multiple sclerosis (VLOMS) is an uncommon form of MS, accounting for only 0.5 percent of all MS patients. Eye movement impairments such as internuclear ophthalmoplegia are common in MS, while horizontal gaze palsy is an uncommon occurrence.</p><p><strong>Case presentation: </strong>We report a case of a patient diagnosed with VLOMS who presented with left horizontal gaze palsy and ipsilateral facial nerve palsy. Brain magnetic resonance imaging showed Dawson's fingers in the left and right periventricular white matter; multiple small, round, hyperintense lesions in the left and right cortex and juxtacortical cerebellar hemisphere; and small hyperintense lesion in the left paramedian pontine reticular formation, suggesting the diagnosis of MS. Oral corticosteroids led to complete resolution of ocular movement and ipsilateral facial nerve palsy.</p><p><strong>Conclusion: </strong>We propose that neuroimaging should be performed in ophthalmoplegia with a pattern representing CNS lesion and oral corticosteroids may be an effective alternative to high-cost intravenous corticosteroids.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"176-183"},"PeriodicalIF":0.4,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140038787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prolonged Button Battery Exposure Leading to Severe Ocular Injury without Heavy Metal Poisoning. 长时间接触纽扣电池导致严重眼部损伤,但未造成重金属中毒。
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-03-01 eCollection Date: 2024-01-01 DOI: 10.1159/000536469
Lifei Chen, Haiyan Gan, Hui Huang, Jiuming Zhang, Fen Tang, Qianqian Lan, Qi Chen, Min Li, Fan Xu, Haibin Zhong
{"title":"Prolonged Button Battery Exposure Leading to Severe Ocular Injury without Heavy Metal Poisoning.","authors":"Lifei Chen, Haiyan Gan, Hui Huang, Jiuming Zhang, Fen Tang, Qianqian Lan, Qi Chen, Min Li, Fan Xu, Haibin Zhong","doi":"10.1159/000536469","DOIUrl":"10.1159/000536469","url":null,"abstract":"<p><strong>Introduction: </strong>Prolonged exposure to a complete button battery can cause severe tissue necrosis in the eye and permanent impairment of visual function. The main mechanism of injury is the current generated by the hydrolysis of tissue fluid at the negative electrode and the production of hydroxide ions.</p><p><strong>Case presentation: </strong>A 3-year-old girl went to the local hospital because of swelling and pain in her right eye of 12-h duration. The local doctor performed an orbital CT (computed tomography) scan and found a foreign body between the right eyelid and the eyeball. The foreign body was removed immediately under general anesthesia. In addition, it was found that the foreign body was a button battery, but it prolonged 39 h from the onset of the child's symptoms. The child underwent a second operation in our hospital and received amniotic membrane transplantation combined with conjunctival flap coverage. Topical corticosteroid and antibiotic eye ointment were continued for 3 months after surgery. Local pigmentation was seen, there was no symblepharon, but the cornea was still opaque and the visual acuity was only FC (finger count). In this particular case, heavy metal testing conducted on the child's blood fortunately revealed that the levels were within the normal range.</p><p><strong>Conclusion: </strong>Early detection and urgent removal of button battery are crucial in order to minimize exposure time. We should also be concerned about heavy metals in the blood. Children should be kept away from button batteries as much as possible to avoid such injury.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"170-175"},"PeriodicalIF":0.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10907000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140020992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Cryptococcal Choroiditis in a Human Immunodeficiency Virus-Infected Patient: A Case Report. 人类免疫缺陷病毒感染者的双侧隐球菌脉络膜炎:病例报告。
IF 0.4
Case Reports in Ophthalmology Pub Date : 2024-02-14 eCollection Date: 2024-01-01 DOI: 10.1159/000535151
Sara Sanfilippo, Bastien Docquier, Paul Louis Schrooyen, Dorine Makhoul, Aurélie Le
{"title":"Bilateral Cryptococcal Choroiditis in a Human Immunodeficiency Virus-Infected Patient: A Case Report.","authors":"Sara Sanfilippo, Bastien Docquier, Paul Louis Schrooyen, Dorine Makhoul, Aurélie Le","doi":"10.1159/000535151","DOIUrl":"10.1159/000535151","url":null,"abstract":"<p><strong>Introduction: </strong>In this case report, we present a rare case of bilateral cryptococcal choroiditis following a diagnosis of meningitis in a 38-year-old woman with HIV.</p><p><strong>Case presentation: </strong>A Colombian woman, newly diagnosed with HIV, presented with respiratory distress followed by meningeal syndrome. Further evaluation revealed cryptococcal meningitis caused by <i>Cryptococcus neoformans</i>, confirmed through cerebrospinal fluid analysis and brain magnetic resonance imaging. The patient reported mild blurred vision, prompting an ophthalmic examination that included indocyanine green angiography. The findings revealed signs of HIV retinopathy and multifocal choroidal lesions in both eyes, suggestive of choroidal cryptococcosis. Treatment involved intravenous administration of amphotericin B and flucytosine, followed by oral fluconazole. Subsequently, the choroidal lesions gradually regressed, and regular monitoring demonstrated no signs of recurrence.</p><p><strong>Conclusion: </strong>Cryptococcal choroiditis, though exceptionally rare, can occur in HIV-positive patients with disseminated cryptococcosis. Ophthalmologists should maintain a high index of suspicion for opportunistic infections, even in the absence of pronounced ocular symptoms, particularly in immunocompromised individuals. Early diagnosis and appropriate treatment are crucial for achieving favorable outcomes in such cases.</p>","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"157-162"},"PeriodicalIF":0.4,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139734483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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