Case Reports in Ophthalmology最新文献_第9页

A Case of Inflammatory Juvenile Conjunctival Nevus with a Rare Histopathological Type. 一例罕见组织病理学类型的炎性幼年结膜痣

IF 0.5

Case Reports in Ophthalmology Pub Date : 2024-05-17 eCollection Date: 2024-01-01 DOI: 10.1159/000538593

Chihiro Iwata, Yuichi Asahina, Takashi Ono, Yukako Taketani, Mikiko Kimakura, Tetsuya Toyono, Mariko Tanaka, Makoto Aihara, Takashi Miyai

{"title":"A Case of Inflammatory Juvenile Conjunctival Nevus with a Rare Histopathological Type.","authors":"Chihiro Iwata, Yuichi Asahina, Takashi Ono, Yukako Taketani, Mikiko Kimakura, Tetsuya Toyono, Mariko Tanaka, Makoto Aihara, Takashi Miyai","doi":"10.1159/000538593","DOIUrl":"10.1159/000538593","url":null,"abstract":"Introduction: Inflammatory juvenile conjunctival nevus (IJCN) is a rare condition affecting both children and adolescents. It has misleading clinical and histopathological features; therefore, careful assessment is necessary. We present a case of IJCN with a rare pathological type and misleading histopathological features.Case presentation: A 13-year-old girl with IJCN in the right eye was treated with antiallergic and steroid eye drops but showed no response and was referred to our hospital for excisional biopsy. Slit-lamp examination revealed a nonpigmented juxtalimbal tumor in the right eye. Histopathologically, nevus cells with mild nuclear atypia proliferated within the conjunctival epithelium. Confluent growth of junctional nests, conjunctival cysts, and prominent inflammatory infiltration were also observed. Considering the young age of the patient and immunohistochemical characteristics (HMB-45, SOX10, p16 and Ki-67), the patient was finally diagnosed with IJCN. IJCN has three pathological subtypes - compound, subepithelial, and junctional - depending on the location of the nevus cells. This case was diagnosed as a rare junctional type, as most of the examined sections only showed lesions within the epithelium; no lesions were clearly identified extending beneath the epithelium.Conclusion: The pathological diagnosis of IJCN is difficult because some features of IJCN suggest malignancy. Detailed microscopic examination, immunohistochemical staining, and the patient's young age helped render a final diagnosis.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"443-447"},"PeriodicalIF":0.5,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11250155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lower Eyelid Merkel Cell Carcinoma in a Non-Immunocompromised Young Female: A Case Report. 一名非免疫缺陷年轻女性的下眼睑梅克尔细胞癌：病例报告。

IF 0.5

Case Reports in Ophthalmology Pub Date : 2024-05-17 eCollection Date: 2024-01-01 DOI: 10.1159/000536098

Yoshifumi Komatsu, Yoshiyuki Kitaguchi, Masako Kurashige, Takeshi Morimoto, Kohji Nishida

引用次数: 0

Successful Management of Acute Streptococcal Meningoencephalitis Complicated by Bilateral Third-Nerve Palsies, Wall-Eyed Bilateral Internuclear Ophthalmoplegia, Blindness, and Deafness: Case Report. 成功治疗急性链球菌脑膜脑炎并发双侧第三神经麻痹、壁眼型双侧核间性眼肌麻痹、失明和失聪：病例报告。

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.1159/000538821

Amitouj S Sidhu, Charles E L Walker, Thomas D Riisfeldt, Peter J Tweedie, Natasha Gerbis, Emily J Sutherland, Neil G Simon, Lucy K Somerville, Ross Bradbury, Raymond Cook, Jonathon Parkinson, Robert Goetti, Ian C Francis

{"title":"Successful Management of Acute Streptococcal Meningoencephalitis Complicated by Bilateral Third-Nerve Palsies, Wall-Eyed Bilateral Internuclear Ophthalmoplegia, Blindness, and Deafness: Case Report.","authors":"Amitouj S Sidhu, Charles E L Walker, Thomas D Riisfeldt, Peter J Tweedie, Natasha Gerbis, Emily J Sutherland, Neil G Simon, Lucy K Somerville, Ross Bradbury, Raymond Cook, Jonathon Parkinson, Robert Goetti, Ian C Francis","doi":"10.1159/000538821","DOIUrl":"10.1159/000538821","url":null,"abstract":"Introduction: Streptococcal meningoencephalitis (SME) is a rare, and frequently lethal, acute infection, and inflammation of the central nervous system parenchyma, with associated meningeal involvement. Bacterial meningoencephalitis is generally associated with high rates of morbidity and mortality, despite available antimicrobial and corticosteroid treatments. While Streptococcus pneumoniae is well recognised to cause bacterial meningitis, direct extension into the central nervous system parenchyma is rare.Case presentation: A previously well 49-year-old man presented with sudden onset severe headache, fevers, neck stiffness, and reduced consciousness. The manifestations of SME in this patient were bilateral pupil-involving third-nerve palsies, wall-eyed bilateral internuclear ophthalmoplegia (WEBINO), bilateral blindness, bilateral deafness, a right lower motor neuron facial palsy, and upper motor neuron signs in his limbs. Initially, a partial response to high dose intravenous antibiotics occurred, but with administration of intravenous corticosteroids, further substantial resolution of the patient's neurological and neuro-ophthalmological deficits occurred.Conclusion: This case highlights the benefit of multidisciplinary diagnostic and therapeutic interventions in a case of SME complicated by bilateral pupil-involving third-nerve palsies, WEBINO, bilateral blindness, bilateral deafness, a right lower motor neuron facial palsy, and upper motor neuron signs. It appears to be the first reported case of SME with this rare collection of neuro-ophthalmological abnormalities.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"423-429"},"PeriodicalIF":0.4,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11078538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epibulbar Complex Choristoma Containing Bone: A Case Report and Closer Look at Classifications. 含骨的上唇复发性绒毛膜瘤：病例报告和分类细读。

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.1159/000538824

Zachary George Angus, Penelope McKelvie, Thomas G Hardy

{"title":"Epibulbar Complex Choristoma Containing Bone: A Case Report and Closer Look at Classifications.","authors":"Zachary George Angus, Penelope McKelvie, Thomas G Hardy","doi":"10.1159/000538824","DOIUrl":"10.1159/000538824","url":null,"abstract":"Introduction: Epibulbar choristoma is a benign congenital lesion containing histologically normal-appearing tissue in an abnormal ectopic location. An epibulbar choristoma is classified as either epibulbar dermoid, dermolipoma, or complex choristoma based on histological examination. The case presented was a presumed epibulbar dermolipoma with no signs of ossification on imaging, examination, or intraoperatively until the specimen was examined histologically, clarifying the lesion as an epibulbar complex choristoma. Reassuringly, the presence of bone in such lesions should not change management.Case presentation: A mother noticed a small fleshy mass on her 9-year-old daughter's superotemporal bulbar conjunctiva. The suspected epibulbar dermolipoma was confirmed with MRI and initially managed conservatively. Two years later, she was referred for apparent growth and cosmetic concerns, and she underwent surgical debulking.Conclusion: We present this case for its unusual presentation and histological findings. Orbital surgeons should be aware of the possibility of ossification of epibulbar choristomas and avoid confusion with alternative diagnoses. Clarification of the latest classification system for epibulbar choristomas is provided.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"418-422"},"PeriodicalIF":0.4,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11078539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overlapping Spots of Photodynamic Therapy for Treatment of Choroidal Hemangioma in Sturge-Weber Syndrome: A Case Report. 光动力疗法治疗 Sturge-Weber 综合征脉络膜血管瘤的重叠点：病例报告。

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.1159/000535948

Alex Y Pai, Michael M Han, Sameh Mosaed, Mohammad Riazi Esfahani

{"title":"Overlapping Spots of Photodynamic Therapy for Treatment of Choroidal Hemangioma in Sturge-Weber Syndrome: A Case Report.","authors":"Alex Y Pai, Michael M Han, Sameh Mosaed, Mohammad Riazi Esfahani","doi":"10.1159/000535948","DOIUrl":"https://doi.org/10.1159/000535948","url":null,"abstract":"Introduction: Photodynamic therapy (PDT) has shown substantial benefit in the treatment of choroidal hemangioma (CH) in recent years. This report describes the use of PDT with overlapping spots in a patient with Sturge-Weber syndrome (SWS) and large circumscribed CH.Case presentation: A 9-year-old girl with SWS and a history of glaucoma in her left eye was referred to a retina clinic for possible macular changes. Examination revealed decreased vision in the left eye, pigmentary changes in the macula, and choroidal thickening in the posterior pole. After being lost to follow-up for 2 years, the patient returned with further vision deterioration with best-corrected visual acuity (BCVA) of 20/150 and new subretinal fluid (SRF). Imaging findings were consistent with a diagnosis of CH and SRF. PDT with verteporfin was initiated on the entire area with multiple overlapping spots, resulting in resolution of SRF and improvement in visual acuity and choroidal contour. At 18-month post-treatment, the patient's BCVA was 20/25 with no recurrence of SRF or increased choroidal thickening. Significant pigmentary changes and subretinal hyper-reflective material were observed in the OCT of the treated area.Conclusion: Multiple overlapping laser spots of PDT can result in longstanding regression of large circumscribed CH in a patient with SWS with excellent final visual acuity. However, significant subretinal changes may also result following this method of treatment.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"411-417"},"PeriodicalIF":0.4,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Late-Onset Pigment Dispersion Syndrome following Implantable Collamer Lens Surgery: A Case Report. 植入式角膜塑形镜手术后的双侧迟发性色素分散综合征：病例报告。

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-04-26 eCollection Date: 2024-01-01 DOI: 10.1159/000538547

Andreas Katsimpris, Manjula Kumarasamy

{"title":"Bilateral Late-Onset Pigment Dispersion Syndrome following Implantable Collamer Lens Surgery: A Case Report.","authors":"Andreas Katsimpris, Manjula Kumarasamy","doi":"10.1159/000538547","DOIUrl":"https://doi.org/10.1159/000538547","url":null,"abstract":"Introduction: We report a case of bilateral pigment dispersion syndrome after 13 years of uncomplicated implantable collamer lens (ICL) surgery.Case presentation: A 53-year-old woman was referred from her optometrist to our glaucoma clinic due to early superonasal visual field loss in both eyes. She was asymptomatic with no changes in visual acuity and had undergone bilateral ICL implantation 13 years ago to correct her high myopia. Clinical examination revealed pigment deposition on the corneal endothelium, iris transillumination defects, and iris vaulting at the areas of contact with the ICL. Gonioscopy showed open angles with significant pigmentation of the trabecular meshwork. The diagnosis of pigment dispersion syndrome secondary to ICL implantation was made, and subsequent follow-up visits demonstrated normal intraocular pressure IOP and stable visual fields.Conclusion: Pigmentary dispersion syndrome can occur several years after ICL implantation. This case report emphasizes the need for long-term follow-up and monitoring after ICL surgery.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"399-405"},"PeriodicalIF":0.4,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11052560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stress-Induced Oculogyric Crisis in Septo-Optic Dysplasia: Case Report. 眼球内膜发育不全症的压力性眼球危机：病例报告。

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-04-26 eCollection Date: 2024-01-01 DOI: 10.1159/000534493

Phillip Keys, Pamela Davila-Siliezar, Noor Laylani, Andrew G Lee

{"title":"Stress-Induced Oculogyric Crisis in Septo-Optic Dysplasia: Case Report.","authors":"Phillip Keys, Pamela Davila-Siliezar, Noor Laylani, Andrew G Lee","doi":"10.1159/000534493","DOIUrl":"https://doi.org/10.1159/000534493","url":null,"abstract":"Introduction: Oculogyric crisis (OGC) is a dystonic movement disorder of varying durations that manifests as bilateral paroxysmal upward eye deviation accompanied by involuntary blinking, tongue protrusion, and autonomic symptoms. Separately, septo-optic dysplasia (SOD) is a congenital disorder involving hypoplasia of the optic nerve as well as hypothalamic and pituitary abnormalities. In the presented case, we report a case of OGC in the setting of SOD with proposed pathogenesis.Case presentation: A 27-year-old female presented with a history of SOD (optic nerve hypoplasia and hypopituitarism) with acute, recurrent, painless, bilateral, intermittent, simultaneous tonic conjugate upward eye deviation (i.e., OGC) and dystonic body posturing. She experienced her first episode upon meeting her biological sister for the first time at a loud, crowded public restaurant with continued episodes of OGC increasing in frequency and duration over the subsequent months. She later responded well to treatment with carbidopa/levodopa.Conclusion: Based on our current understanding of OGC, we hypothesize that acute stressful life events in the setting of prior hypothalamic-pituitary axis dysfunction secondary to SOD could lower the threshold for developing OGC. Although most cases of OGC are idiopathic, various etiologies including medications, stress, and hormonal imbalance have been postulated as possible pathogenic mechanisms. We describe a case of SOD with OGC, and based upon our review of the English language ophthalmic literature, we believe that our case is novel.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"406-410"},"PeriodicalIF":0.4,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11052561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late-Onset Panuveitis in a Chinese Girl with Sporadic Blau Syndrome: A Case Report. 一名患有散发性布劳综合征的中国女孩的晚发性葡萄膜炎：病例报告。

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-04-24 eCollection Date: 2024-01-01 DOI: 10.1159/000536005

Zicheng Ma, Xinxiao Gao, Siquan Zhu

引用次数: 0

Increase of Intraocular Pressure after Application of 0.125% Atropine Eye Drops in Children Using Ortho-K Contact Lenses. 使用 0.125% 阿托品滴眼液的儿童眼压升高。

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-04-04 eCollection Date: 2024-01-01 DOI: 10.1159/000538332

Yu Ri Lee, Jehyung Hwang, Jae Suk Kim

引用次数: 0

Primary Conjunctival Embryonal Rhabdomyosarcoma in an 8-Year-Old Girl. 一名 8 岁女孩的原发性结膜胚胎性横纹肌肉瘤

IF 0.4

Case Reports in Ophthalmology Pub Date : 2024-03-28 eCollection Date: 2024-01-01 DOI: 10.1159/000536382

Shima Bakhtiary, Michael Barkley

{"title":"Primary Conjunctival Embryonal Rhabdomyosarcoma in an 8-Year-Old Girl.","authors":"Shima Bakhtiary, Michael Barkley","doi":"10.1159/000536382","DOIUrl":"10.1159/000536382","url":null,"abstract":"Introduction: Rhabdomyosarcoma is a rare paediatric cancer, with the head and neck region representing a major anatomical site for rhabdomyosarcoma. In particular, orbital rhabdomyosarcoma is the most common region among children. However, rhabdomyosarcoma originating from the conjunctiva in paediatric population is a rare disease, and this knowledge is essential in order to ensure prompt treatment and early intervention.Case presentation: We discuss a rare case of primary conjunctival rhabdomyosarcoma in an 8-year-old Caucasian girl. She presented to a paediatric ophthalmology clinic with a 5-day history of a rapidly growing conjunctival lesion in the superior fornix of the right eye. An urgent excisional biopsy was performed which yielded a large 30-mm multilobulated, vascular, and papillomatous specimen with histopathological features consistent with embryonal rhabdomyosarcoma. She was urgently referred to oncology and was treated with systemic chemotherapy.Conclusion: Therapeutical options and prognosis of rhabdomyosarcomas are based on clinical findings, tumour staging, and grouping, combined with histopathological and molecular features. Although rare, it is important to note that in the paediatric population, rhabdomyosarcoma can originate from the conjunctiva. Knowledge of its clinical, histopathological, and imaging characteristics is essential in order to achieve early diagnosis and timely treatment.","PeriodicalId":9635,"journal":{"name":"Case Reports in Ophthalmology","volume":"15 1","pages":"279-283"},"PeriodicalIF":0.4,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10978040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140317850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0