Case Reports in Obstetrics and Gynecology最新文献

{"title":"Vulvar Apocrine Hidrocystoma: A Rare Case Report.","authors":"Nastaran Mahmoudnejad, Peyman Mohammadi Torbati, Niloofar Irandoost","doi":"10.1155/crog/9794934","DOIUrl":"10.1155/crog/9794934","url":null,"abstract":"<p><p>Apocrine hidrocystoma is a rare and benign tumor that usually occurs on the head, neck, and face. Involvement of the vulva is extremely rare, with only a few documented case reports in the literature. The prognosis of the tumor is favorable with surgical excision, with no reported recurrences. Here, we present the case of a 40-year-old woman with a solitary nodule on the labia majora, without any other manifestations. We discuss its management and follow-up course.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"9794934"},"PeriodicalIF":0.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13584320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Canal of Nuck Cysts Presenting as Bartholin's Cysts: A Case Report.","authors":"Reem Chamseddine, Yevgeniya Osipova","doi":"10.1155/crog/5816734","DOIUrl":"https://doi.org/10.1155/crog/5816734","url":null,"abstract":"<p><p>We present the case of a 24-year-old woman with a presentation consistent with Bartholin's cysts ultimately identified as cysts originating from the ducts of the canal. Our study of this patient underscores the need for a comprehensive diagnostic approach in recurrent vulvar cysts. This case illustrates how overlapping clinical features can obscure less common conditions, leading to potential misdiagnosis. Our study of this patient emphasizes the importance of maintaining a broad differential diagnosis when evaluating recurrent vulvar cysts when patients do not respond to standard treatment approaches. Although Bartholin's gland cysts are commonly encountered, canal of Nuck cysts require careful differentiation, through a pathology-based diagnosis, and definitive management through surgery alone.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"5816734"},"PeriodicalIF":0.8,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13580851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolonged Treatment in a Case of Anti-N-Methyl-D-Aspartate Receptor Encephalitis.","authors":"Thuy-Mai Thi Huynh, Ngoc-Trinh Thi Nguyen, Anh-Thu Thi Nguyen, Khanh-Trang Nguyen Huynh, Diem-Tuyet Thi Hoang, Thanh-Viet Pham, Ngoc-Khanh Thi Do, Quoc-Hung Le","doi":"10.1155/crog/8497402","DOIUrl":"https://doi.org/10.1155/crog/8497402","url":null,"abstract":"<p><strong>Background: </strong>Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a rare autoimmune encephalitis. The proposed mechanism relates to the circulating tumor-induced antibody, so the treatment includes tumor removal and immunotherapy. This report is aimed at describing a case of anti-NMDAR encephalitis in a female patient with an ovarian teratoma who required prolonged immunotherapy.</p><p><strong>Case report: </strong>A 17-year-old female presented with a fever before hospital admission, then progressed to neurologic and psychiatric symptoms. The indirect immunofluorescence antibody (IFA) test revealed positive anti-NMDAR immunoglobulin G (IgG) in serum and cerebrospinal fluid (CSF) samples. The patient was diagnosed with teratomas on both ovaries at different times. Two surgeries were performed to remove the tumors. The patient received systemic corticosteroids and 30 sessions of plasmapheresis. After approximately 2 months of treatment, the patient improved significantly and was discharged. At follow-up, she showed good clinical recovery, although mild residual cognitive impairment was noted on formal assessment.</p><p><strong>Conclusions: </strong>This case highlights that, in young women with anti-NMDAR encephalitis, early and thorough evaluation for ovarian teratoma is essential. If recovery remains incomplete after initial surgery and immunotherapy, repeat assessment for occult, residual, or contralateral lesions should be considered. Careful preoperative lesion assessment and fertility-preserving surgical planning may help reduce missed lesions while minimizing unnecessary ovarian tissue loss.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8497402"},"PeriodicalIF":0.8,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncommon Presentation of a Benign Brenner Tumor Mimicking Malignancy: A Case Report.","authors":"Sulaeman Andrianto Susilo, Ali Budi Harsono, Hermin Aminah Usman","doi":"10.1155/crog/8794499","DOIUrl":"10.1155/crog/8794499","url":null,"abstract":"<p><strong>Background and aims: </strong>Brenner tumor (BT) is a rare ovarian epithelial tumor, with approximately 95% of cases being benign. Because of its rarity and nonspecific clinical radiological features, benign BT may mimic ovarian malignancy. We present a case of a benign BT with clinical, radiological, and intraoperative findings suggestive of malignancy.</p><p><strong>Method: </strong>A 69-year-old postmenopausal woman presented with progressive abdominal enlargement, abdominal pain, and a 10 kg weight loss over 2 months. Ultrasonography showed an ovarian mass with both benign and malignant IOTA features, whereas risk of malignancy index-2 (RMI-2) was 1350. Abdominal laparotomy with total hysterectomy, bilateral salpingo-oophorectomy, and omentectomy was performed. Histopathological examination of the ovarian mass demonstrated features suspicious for MBT, whereas epithelial cell clusters identified in the omental specimen raised concern for metastatic involvement. Immunohistochemical examination showed CK7 and p63 positivity in ovarian tumor but negative expression in omental specimen, excluding metastatic BT.</p><p><strong>Result: </strong>Despite the patient's postmenopausal status, large tumor size, elevated CA-125 level, high RMI-2 score, and intraoperative omental adhesion, the final diagnosis was benign BT. The case demonstrates the potential for benign BTs to mimic advanced ovarian malignancy clinically and radiologically. Immunohistochemistry was particularly useful in resolving the diagnostic uncertainty regarding the suspected omental metastasis.</p><p><strong>Conclusion: </strong>Benign BTs may present with features strongly suggestive of malignancy. Careful histopathological evaluation is essential, and immunohistochemistry can provide valuable diagnostic clarification when metastatic involvement or malignant transformation is suspected.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8794499"},"PeriodicalIF":0.8,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare PKHD1 Frameshift Variant Identified in a Prenatally Diagnosed ARPKD Case From a Consanguineous Jordanian Family.","authors":"Oqba Al-Kuran, Reham Albadaineh, Adnan Almallah, Dana Al-Atrash, Duaa Dahbour, Lama Al-Mehaisen","doi":"10.1155/crog/4656543","DOIUrl":"10.1155/crog/4656543","url":null,"abstract":"<p><strong>Introduction: </strong>Polycystic kidney disease (PKD) is a condition that encompasses the development of multiple benign cysts in the kidneys and other organs. Hereditary PKD can be classified as autosomal dominant polycystic kidney disease (ADPKD) or autosomal recessive polycystic disease (ARPKD). These two forms differ primarily in their age of onset and clinical presentation. ADPKD is usually diagnosed during young adulthood, whereas ARPKD presents a wide range of clinical manifestations with approximately one-third of patients presenting before the first year of life, one-third between 1 and 20 years of age, and the remaining one-third after 20 years of age. ARPKD represents the severe form, typically presenting in infancy with significant renal and hepatic involvement. Hereditary and congenital forms are known to be caused by certain genetic defects associated with dysfunction of the primary cilia in the tubular epithelium. To the best of our knowledge, no similar cases have been reported in Jordan or neighboring countries.</p><p><strong>Case presentation: </strong>We report a case of ARPKD in one fetus of a twin pregnancy. Prenatal ultrasonography at the 20th week of gestation revealed characteristic findings of ARPKD in one fetus. The twins were delivered at 36 weeks gestation. The affected twin died shortly after birth because of severe respiratory distress. Postnatal exome sequencing (ES) on the deceased infant identified a pathogenic homozygous variant in the polycystic kidney and hepatic disease (<i>PKHD1)</i> gene, supporting the genetic diagnosis of ARPKD.</p><p><strong>Discussion: </strong>Management of ARPKD requires multidisciplinary care, emphasizing supportive therapy and monitoring for complications. Genetic counseling is pivotal, highlighting the risk of disease transmission and the role of prenatal genetic screening for at-risk families.</p><p><strong>Conclusions: </strong>Our case highlights the importance of early diagnosis, comprehensive management, and genetic counseling in ARPKD, particularly within the Jordanian population as well as neighboring demographics with high rates of consanguinity.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"4656543"},"PeriodicalIF":0.8,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148954808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy-Associated Isolated Fallopian Tube Torsion With a True Knot Managed by Laparoscopic Salpingectomy: A Case Report.","authors":"Ahmed Abdeltawab","doi":"10.1155/crog/8852614","DOIUrl":"10.1155/crog/8852614","url":null,"abstract":"<p><p>Isolated torsion of the fallopian tube is a rare cause of acute abdomen in women of reproductive age, with an estimated annual incidence of approximately one per 1.5 million women. Its occurrence during pregnancy is rarer still, with fewer than 50 cases published. We present a 25-year-old primigravida at 27+6 weeks of gestation who was admitted to Farwaniya Hospital, Kuwait, with persistent right iliac fossa pain refractory to conservative management, associated with nausea and dysuria, on a background of recurrent urinary tract infection. Laboratory investigations showed leucocytosis and mild anaemia. Transabdominal ultrasound with colour Doppler identified a small simple right adnexal cystic lesion with preserved ovarian vascularity, and pelvic magnetic resonance imaging demonstrated an encysted fluid collection in the right iliac fossa of probable adnexal origin, together with a nondistended, normal-appearing appendix showing no features of inflammation. Following failure of conservative treatment and after counselling of the patient and her husband, diagnostic laparoscopy was performed. The right fallopian tube was gangrenous, twisted repeatedly upon itself and configured as a true knot, and salpingectomy was performed. Both ovaries and the appendix were macroscopically normal. Histopathology confirmed haemorrhagic infarction with epithelial necrosis of the tubal mucosa. The postoperative course was uneventful and the pregnancy continued to term, with spontaneous vaginal delivery of a healthy female neonate at 40+3 weeks of gestation. This case illustrates the diagnostic difficulty of isolated tubal torsion in pregnancy, in which urinary symptoms and non-specific imaging readily divert attention towards pyelonephritis, and supports laparoscopy as a safe and definitive diagnostic and therapeutic option in the second trimester. The intraoperative finding of a true knot is unusual and is documented here with annotated operative imaging.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8852614"},"PeriodicalIF":0.8,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13564104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148954795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Catastrophic Postpartum Acute Pulmonary Embolism With Extracorporeal Membrane Oxygenation Support and Thromboaspiration: A Case Report.","authors":"Fabio Varón-Vega, María Camila Martínez-Ayala, Eduardo Tuta-Quintero, Dario Echeverri, José Rojas-Suarez","doi":"10.1155/crog/5555153","DOIUrl":"10.1155/crog/5555153","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary embolism (PE) is a leading cause of maternal mortality during the postpartum period and is associated with significant hemodynamic instability. High-risk PE, characterized by obstructive shock and right ventricular failure, requires immediate and aggressive intervention. In cases refractory to conventional therapies, extracorporeal membrane oxygenation (ECMO) may serve as a life-saving bridge to definitive treatment.</p><p><strong>Case description: </strong>We report the case of a 28-year-old woman who developed high-risk acute PE 48 h after an uncomplicated vaginal delivery. She presented with severe obstructive shock and right ventricular failure unresponsive to systemic thrombolysis and standard hemodynamic support. Due to progressive clinical deterioration, venoarterial ECMO was initiated as a rescue therapy, which led to hemodynamic stabilization. Mechanical thromboaspiration was subsequently performed, achieving successful thrombus removal and clinical improvement.</p><p><strong>Conclusion: </strong>This case highlights the critical role of ECMO as a therapeutic bridge in patients with high-risk PE and hemodynamic collapse. The combination of ECMO with catheter-directed thromboaspiration proved effective in restoring hemodynamic stability and resolving thrombotic obstruction, offering a viable rescue strategy in life-threatening postpartum PE.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"5555153"},"PeriodicalIF":0.8,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13556166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148918164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Multifocal Ovarian Teratomas and Ovarian Torsion in a Young Woman With Polycystic Ovarian Syndrome: A Case Report.","authors":"Megan R Messina, Marcia H Varella, Francisco J Fajardo, Robert Hunter, Nicole Henry","doi":"10.1155/crog/6856494","DOIUrl":"10.1155/crog/6856494","url":null,"abstract":"<p><strong>Background: </strong>Ovarian dermoid cysts are common benign neoplasms that typically manifest as a solitary lesion. Bilateral multifocal presentations, particularly in the context of polycystic ovarian syndrome (PCOS), are exceptionally rare and pose significant diagnostic challenges.</p><p><strong>Case presentation: </strong>A 22-year-old nulligravid Caucasian woman with a history of PCOS presented with acute, severe lower abdominal pain accompanied by nausea and vomiting. Initial imaging revealed large bilateral ovarian masses with features consistent with dermoid cysts and clinical findings suggestive of a right ovarian torsion. Despite a prior computed tomography (CT) scan indicating bilateral ovarian cysts, the patient attributed her symptoms to PCOS-related changes, delaying timely evaluation. Intraoperative findings during an exploratory laparotomy confirmed the presence of more than five distinct dermoid teratomas on each ovary. Bilateral ovarian cystectomies were performed with careful preservation of ovarian stromal tissue, and histopathological analysis verified the diagnosis of mature cystic teratomas.</p><p><strong>Conclusion: </strong>This case underscores the critical need for early differentiation between PCOS-related cysts and ovarian dermoid cysts to avert complications such as ovarian torsion and to preserve fertility. It also highlights the essential role of clear and effective communication between healthcare providers and patients in ensuring timely diagnosis and intervention. Misinterpretation of clinical symptoms can lead to delayed presentation with potentially deleterious effects on future fertility.</p><p><strong>Teaching point: </strong>A CT scan obtained during the patient's initial evaluation revealed ovarian teratomas; however, the patient mistakenly believed these masses represented her typical PCOS-associated cysts rather than pathology of a different etiology. This misconception delayed recognition of the severity of her condition and underscores the importance of clear physician-patient communication to ensure patients understand the significance of their diagnoses, particularly when fertility and overall well-being may be affected.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"6856494"},"PeriodicalIF":0.8,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148905152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gabapentin for the Management of Suspected Cannabis Withdrawal in a Pregnant Patient With a History of Cannabinoid Hyperemesis Syndrome: A Case Report.","authors":"Anne-Marie Turcotte, Charlotte Lemieux-Bourque, Catherine McCarey, Katéri Lévesque, Geneviève Kerkerian, Audrey Ann Labrecque","doi":"10.1155/crog/3043344","DOIUrl":"10.1155/crog/3043344","url":null,"abstract":"<p><p>Cannabinoid hyperemesis syndrome (CHS) is a rare but increasingly recognized condition among chronic cannabis users, characterized by cyclic nausea, vomiting, and relief with hot bathing. During pregnancy, CHS may mimic hyperemesis gravidarum (HG), complicating diagnosis and management. We report the case of a 24-year-old pregnant patient who presented at 20 weeks' gestation with recurrent nausea, vomiting, and labile hypertension. Investigations ruled out preeclampsia and secondary causes of hypertension. She met DSM-5 criteria for cannabis use disorder, had a prior hospitalization for CHS, and had recently reduced her cannabis use, raising concern for withdrawal as a contributing factor to her presentation. Gabapentin was initiated off-label after an Addiction Medicine consultation, resulting in resolution of symptoms and normalization of blood pressure within 24 h. To our knowledge, this is the first reported use of gabapentin in a pregnant patient with a history of CHS and suspected cannabis withdrawal. This report highlights the importance of screening for cannabis use, recent reduction or cessation, and withdrawal symptoms in pregnant patients presenting with severe or refractory hyperemesis. In this case, short-term off-label gabapentin use led to rapid symptom resolution without apparent maternal or fetal complications, suggesting that it may be relatively safe in this population, although data remain limited.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"3043344"},"PeriodicalIF":0.8,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13531385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148873116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Diarrhea: A Case Report on Challenges in Both Prenatal and Postnatal Diagnosis.","authors":"H Heinrich, E Pajkrt, M M Tabbers, E van Leeuwen","doi":"10.1155/crog/9987632","DOIUrl":"10.1155/crog/9987632","url":null,"abstract":"<p><p>Prenatal recognition of congenital diarrhea and subsequent diagnosis can facilitate neonatal monitoring and prompt initiation of lifesaving postnatal treatment. We describe two cases with a congenital diarrheal disorder (CDD), highlighting the prenatal course and the diagnostic process. In cases of fetal dilated bowel loops, particularly with a characteristic honeycomb appearance, prenatal genetic testing for CDDs should be considered. After birth, distinguishing diarrhea from urine may be challenging in neonates with suspected congenital diarrhea. Therefore, urinary catheterization or a urine collection bag is recommended to ensure accurate assessment.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"9987632"},"PeriodicalIF":0.8,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148817559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}