Case Reports in Obstetrics and Gynecology最新文献_第2页

Case Report on Spontaneous Uterine Rupture in the Early Second Trimester: A Rare but Life-Threatening Event. 妊娠中期早期自发性子宫破裂病例报告：罕见但危及生命的事件。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-23 eCollection Date: 2026-01-01 DOI: 10.1155/crog/9949364

Minh Tam Le, Ngoc Anh Thi Vo, Duy Trong Tran, Thanh Huyen Thi Ho, Vu Quoc Huy Nguyen

{"title":"Case Report on Spontaneous Uterine Rupture in the Early Second Trimester: A Rare but Life-Threatening Event.","authors":"Minh Tam Le, Ngoc Anh Thi Vo, Duy Trong Tran, Thanh Huyen Thi Ho, Vu Quoc Huy Nguyen","doi":"10.1155/crog/9949364","DOIUrl":"https://doi.org/10.1155/crog/9949364","url":null,"abstract":"Spontaneous uterine rupture during the first half of pregnancy is extremely uncommon and presents significant diagnostic and therapeutic challenges. This case report details a 27-year-old gravida 3 para 1 woman at 14 weeks of gestation who experienced acute abdominal pain and hypovolemic shock. Despite the absence of previous uterine surgery, imaging revealed a significant hemoperitoneum, and subsequent emergency laparoscopic and laparotomy validated a uterine fundal rupture attributable to placenta accreta spectrum (PAS). The uterus was successfully preserved after surgical repair. Histopathological examination confirmed localized myometrial infiltration by placental tissue, consistent with PAS. This report emphasizes the necessity of including PAS-related uterine rupture in the differential diagnosis of acute abdomen during early pregnancy, even when classical risk markers are absent. The example underscores the need of timely surgical intervention in securing positive mother outcomes and maintaining reproductive potential. The postoperative course was uneventful, and the patient was discharged in stable condition with preservation of uterine integrity. This article seeks to enhance clinical knowledge and promote vigilance among obstetricians and emergency physicians on early-pregnancy uterine rupture by contributing to the scarce literature on the subject.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"9949364"},"PeriodicalIF":0.8,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilization of Transvaginal Morcellation for Large Cervical Fibroid During Laparoscopic Assisted Hysterectomy: A Case Report. 腹腔镜辅助子宫切除术中经阴道分切术治疗大宫颈肌瘤1例。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-21 eCollection Date: 2026-01-01 DOI: 10.1155/crog/5522455

Apoorva Kakkilaya, Karren Lewis

{"title":"Utilization of Transvaginal Morcellation for Large Cervical Fibroid During Laparoscopic Assisted Hysterectomy: A Case Report.","authors":"Apoorva Kakkilaya, Karren Lewis","doi":"10.1155/crog/5522455","DOIUrl":"https://doi.org/10.1155/crog/5522455","url":null,"abstract":"Introduction: Cervical fibroids are a rare subtype of uterine fibroid (0.6%) which may cause pelvic pain and abnormal uterine bleeding. When large, they present technical challenges to traditional laparoscopic hysterectomy due to anatomic distortion and limited uterine mobility. This report aims to illustrate a minimally invasive approach to hysterectomy complicated by a large cervical fibroid with limited mobility and laparoscopic visualization.Case description: A 51-year-old G6P5015 woman underwent hysterectomy for alleviation of pelvic pain secondary to an 11 cm fibroid. Intraoperatively, the fibroid occupied the entire posterior cul-de-sac near the right ureter and extended into the right broad ligament with posterior displacement of the cervix. A combined laparoscopic and vaginal approach was used to complete the surgery. The fibroid was morcellated through a transvaginal approach allowing for debulking of the cervix and completion in a minimally invasive fashion. The patient had an uncomplicated postoperative course.Conclusions: The potential for laparoscopic assisted vaginal hysterectomy (LAVH) with transvaginal morcellation of fibroids as an alternative to total abdominal hysterectomy (TAH) is a worthwhile consideration to reduce recovery time and postoperative complications that can accompany TAH.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"5522455"},"PeriodicalIF":0.8,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13100360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Presentation of Vulvar Discoid Lupus Erythematosus Masquerading as Lichen Sclerosus. 罕见的外阴盘状红斑狼疮伪装成硬化苔藓。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-17 eCollection Date: 2026-01-01 DOI: 10.1155/crog/6697676

Asiya Cummings, Joseph M Maurice, Marylee Braniecki

{"title":"A Rare Presentation of Vulvar Discoid Lupus Erythematosus Masquerading as Lichen Sclerosus.","authors":"Asiya Cummings, Joseph M Maurice, Marylee Braniecki","doi":"10.1155/crog/6697676","DOIUrl":"https://doi.org/10.1155/crog/6697676","url":null,"abstract":"Discoid lupus erythematosus (DLE) is a chronic cutaneous manifestation of lupus that may occur independently or precede systemic disease. Vulvar involvement is exceptionally rare and can mimic more common vulvar dermatoses. We report a case of vulvar hypertrophic DLE in a 55-year-old African-American woman with systemic lupus erythematosus who was presented with an asymptomatic erythematous, ulcerated vulvar lesion initially suspected to represent herpes simplex virus infection or lichen sclerosus. Histopathologic examination demonstrated vacuolar interface dermatitis, follicular plugging, basement membrane thickening, and stromal mucin deposition, findings consistent with DLE. The lesion developed during a lupus flare and lacked the pruritus typical of lichen sclerosus. Management included continuation of immunosuppressive therapy with clinical improvement and residual postinflammatory hypopigmentation. This case highlights the importance of considering lupus-related disease in the differential diagnosis of atypical vulvar lesions and underscores the role of biopsy in establishing an accurate diagnosis.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"6697676"},"PeriodicalIF":0.8,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13090533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Challenging Case Report of Severe Asherman's Syndrome: Managing Uterine Perforation During Surgery. 一个具有挑战性的病例报告严重阿什曼综合征：处理子宫穿孔手术。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-16 eCollection Date: 2026-01-01 DOI: 10.1155/crog/8897371

Khishotul Hayati, Artha Falentin Putri Susilo, Mulyanusa Amarullah Ritonga, Tono Djuwantono

{"title":"A Challenging Case Report of Severe Asherman's Syndrome: Managing Uterine Perforation During Surgery.","authors":"Khishotul Hayati, Artha Falentin Putri Susilo, Mulyanusa Amarullah Ritonga, Tono Djuwantono","doi":"10.1155/crog/8897371","DOIUrl":"https://doi.org/10.1155/crog/8897371","url":null,"abstract":"Introduction: Asherman's syndrome (AS), characterized by intrauterine adhesions (IUAs), can significantly distort uterine anatomy and complicate hysteroscopic adhesiolysis. Although hysteroscopic adhesiolysis is the standard treatment, severe adhesions increase the risk of complications such as uterine perforation.Case illustration: We report a 31-year-old woman with severe AS who developed uterine perforation during hysteroscopic adhesiolysis. During dissection of dense adhesions, a small fundal perforation (0.5 cm × 0.5 cm) was suspected after sudden loss of resistance and bleeding. The procedure was immediately halted, and diagnostic laparoscopy confirmed a full-thickness fundal defect that was repaired laparoscopically. After stabilization, hysteroscopic management was resumed with placement of an amnion graft to promote endometrial regeneration. However, intraoperative bleeding recurred, and reassessment revealed enlargement of the perforation. Repeat laparoscopy confirmed a larger fundal defect, which was repaired with definitive laparoscopic hysterorrhaphy. The patient recovered uneventfully, received postoperative hormonal therapy, and resumed menstruation 1 month after surgery.Conclusion: This case highlights the risk of uterine perforation during adhesiolysis in severe AS and emphasizes the importance of early recognition and prompt laparoscopic management. Adjunctive guidance techniques and combined hysteroscopic-laparoscopic approaches may improve procedural safety and help preserve uterine integrity.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8897371"},"PeriodicalIF":0.8,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Placental Site Trophoblastic Tumor: Two Rare Case Report and Literature Review Within a Decade. 胎盘部位滋养细胞瘤：两例罕见病例报告及近十年文献复习。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-10 eCollection Date: 2026-01-01 DOI: 10.1155/crog/9928611

Yiqi Guan, Jinsong Han, Kun Zhang, Yiting Wang

引用次数: 0

A Rare Massive Seromucinous Cystadenoma of the Ovary in a 26-Year-Old Female Persisting for 9 Years: A Case Report. 一26岁女性罕见的巨大卵巢浆液粘液囊腺瘤，持续9年1例。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-09 eCollection Date: 2026-01-01 DOI: 10.1155/crog/5887168

Marah Kakeh, Mohammad Alhalabi, Wael Wazan, Rasha Abbassi, Abeer Kanjawi, Haitham Abbassi

{"title":"A Rare Massive Seromucinous Cystadenoma of the Ovary in a 26-Year-Old Female Persisting for 9 Years: A Case Report.","authors":"Marah Kakeh, Mohammad Alhalabi, Wael Wazan, Rasha Abbassi, Abeer Kanjawi, Haitham Abbassi","doi":"10.1155/crog/5887168","DOIUrl":"https://doi.org/10.1155/crog/5887168","url":null,"abstract":"Giant ovarian tumors (GOTs) are uncommon ovary neoplasms with no universally accepted definition. They are typically noncancerous, with a mucinous subtype being the most common characteristic. Epithelial ovarian tumors are classified by cell type into serous, endometrioid, clear cell, mucinous, seromucinous, or transitional. Seromucinous cystadenomas are largely asymptomatic and can present with massive dimensions in late diagnoses, especially in low-to-middle-income regions. In this case, a 26-year-old nulliparous Arab woman presented with a giant ovarian cyst in her reproductive age, undiagnosed for 9 years, which turned out to be a benign histopathology of seromucinous cystadenoma. The clinical presentation was nonspecific, as large ovarian cysts are often asymptomatic until they reach a substantial size to affect the quality of life and fertility. She had progressive abdominal swelling first noticed 6 years ago, but she started developing a feeling of fullness, constipation, nausea, vomiting, and urinary hesitancy with painful micturition 5 months prior to presentation with marked distress. The cystadenoma was excised without complications, through the exploratory laparotomy, and a left salpingo-oophorectomy with right cystectomy was performed. Seromucinous cystadenomas were first classified in 2014 by the World Health Organization (WHO) as a new entity and a rare subtype of ovarian epithelial tumors. Patients with benign seromucinous cystadenomas have an excellent prognosis, especially with complete surgical removal. Raising awareness and increasing access to gynecological care in low- and middle-income countries are essential for the long-term well-being and health of patients with giant ovarian cysts.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"5887168"},"PeriodicalIF":0.8,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13066506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Third Delivery in a Chinese Patient With Anomalous Origin of Left Coronary Artery From Pulmonary Artery (ALCAPA): A Case Report. 中国一例左冠状动脉起源地异常（ALCAPA）患者第三次分娩1例。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-09 eCollection Date: 2026-01-01 DOI: 10.1155/crog/4830284

He Zhao, Dawei Zhang, Yanna Li, Zhen Fang, Nan Zhang, Jun Zhang

{"title":"Third Delivery in a Chinese Patient With Anomalous Origin of Left Coronary Artery From Pulmonary Artery (ALCAPA): A Case Report.","authors":"He Zhao, Dawei Zhang, Yanna Li, Zhen Fang, Nan Zhang, Jun Zhang","doi":"10.1155/crog/4830284","DOIUrl":"https://doi.org/10.1155/crog/4830284","url":null,"abstract":"Background: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital defect that poses a significant risk of myocardial ischemia and sudden death, especially during the hemodynamic stresses of pregnancy. Although surgical correction is standard, the management of asymptomatic adult-type ALCAPA diagnosed during pregnancy remains a high-stakes clinical challenge.Case presentation: We report the case of a 36-year-old multiparous woman with incidentally diagnosed adult-type ALCAPA during her third pregnancy. Serial echocardiography revealed moderate mitral regurgitation. The pregnancy was complicated by superimposed preeclampsia at 33 weeks. A dedicated multidisciplinary team implemented a tailored plan for labor induction at 37 weeks in a hybrid operating room, employing epidural analgesia and continuous hemodynamic monitoring. The patient underwent a successful vaginal delivery of a healthy infant. Intriguingly, mitral regurgitation transiently worsened to severe on postpartum Day 3 but significantly improved to mild by Day 7, correlating with resolution of the pregnancy-induced volume load. Coronary CTA postpartum confirmed the diagnosis.Discussion: Multidisciplinary planning enables safe vaginal delivery in select ALCAPA pregnancies. Dynamic peripartum changes in mitral regurgitation underline the role of volume shifts and the need for serial echocardiography to guide management and time definitive surgery.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"4830284"},"PeriodicalIF":0.8,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ruptured Ovarian Ectopic Pregnancy Managed Laparoscopically With Subsequent Term Delivery After 2 years Follow-Up: A Case Report and Literature Review. 随访2年后腹腔镜治疗卵巢宫外孕破裂并足月分娩：1例报告及文献复习。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-09 eCollection Date: 2026-01-01 DOI: 10.1155/crog/8974058

Elizabeth Bajomo, Asma Aziz, Mona Sharma

{"title":"Ruptured Ovarian Ectopic Pregnancy Managed Laparoscopically With Subsequent Term Delivery After 2 years Follow-Up: A Case Report and Literature Review.","authors":"Elizabeth Bajomo, Asma Aziz, Mona Sharma","doi":"10.1155/crog/8974058","DOIUrl":"https://doi.org/10.1155/crog/8974058","url":null,"abstract":"Background: An ovarian ectopic pregnancy (OEP) is a very rare form of ectopic pregnancy. Ectopic pregnancies are 2% of pregnancies, and OEP are 0.5%-3% of all ectopic pregnancies, with an even rarer risk of recurrence. Diagnosis is aided via ultrasound and surgical assessment, but confirmation is via histopathology.Case: We present a case of a woman in her late 20 s (Gravida 2, Para 1-previous normal vaginal delivery at term) with a planned pregnancy who had presented after a private scan to find a right-sided OEP and free fluid in her abdomen. She had only complained of mild lower abdominal cramping and no pervaginal bleeding. After evaluation, including pelvic ultrasound in our Early Pregnancy Assessment Unit (EPAU) that suspected a right OEP, she had a laparoscopic resection of the right ovarian ectopic tissue, and histopathology confirmed OEP. She recovered well and went home the next day. Serum BHCG returned to normal after repeated testing for 4 weeks, her periods returned to normal after 3 months, and she had a pelvic ultrasound scan 8 months later which showed normal ovaries. Two years later, she conceived naturally and delivered vaginally at term as a low-risk uncomplicated pregnancy.Conclusion: An OEP is very rare but can be effectively managed laparoscopically with very good outcomes and fertility preservation. Full-term delivery outcome observed in this case after 2-year follow-up.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8974058"},"PeriodicalIF":0.8,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful Maternal-Assisted Cesarean Using a Modified Australian Protocol. 使用改进的澳大利亚方案成功的产妇辅助剖宫产。

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-09 eCollection Date: 2026-01-01 DOI: 10.1155/crog/7684108

Caroline Lamoutte, Adaeze Anamege, Lauren Silva, Joanne J Tanner, Natalie Elphinstone, Adam L Wendling, Adetola F Louis-Jacques

{"title":"Successful Maternal-Assisted Cesarean Using a Modified Australian Protocol.","authors":"Caroline Lamoutte, Adaeze Anamege, Lauren Silva, Joanne J Tanner, Natalie Elphinstone, Adam L Wendling, Adetola F Louis-Jacques","doi":"10.1155/crog/7684108","DOIUrl":"https://doi.org/10.1155/crog/7684108","url":null,"abstract":"Background: Several delivery methods such as the natural, gentle, Charité, and family-centered cesareans have been introduced to labor and delivery units to help facilitate immediate skin-to-skin, earlier breastfeeding, and bonding, as well as increase patient satisfaction with the birthing experience. For patients who deliver by cesarean and desire further involvement in the delivery process, maternal-assisted cesarean (MAC) may be an option.Case presentation: This case details a MAC at 39 weeks gestational age (GA) for a 31-year-old female with a history of two unplanned cesareans. The first was due to arrest of dilation and nonreassuring fetal heart tracing, and the second followed a failed trial of labor. In this current case, the patient desired a controlled delivery she could actively participate in. Following multidisciplinary planning and simulation, the cesarean was performed with modifications to maintain sterility while allowing maternal participation. After delivery of the fetal head and shoulders, sterile drapes were lowered, and the patient, guided by the surgical team, assisted in delivering the newborn onto her chest. Both mother and newborn remained stable postoperatively.Conclusion: This emerging patient-centered cesarean enables active participation of the patient during delivery while maintaining surgical safety. Despite its rising popularity, studies are needed to evaluate its risks and benefits before wider adoption.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"7684108"},"PeriodicalIF":0.8,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herpes Simplex Virus 1 Encephalitis in First Trimester of Pregnancy: A Case Report. 妊娠早期单纯疱疹病毒1型脑炎1例报告

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Case Reports in Obstetrics and Gynecology Pub Date : 2026-04-08 eCollection Date: 2026-01-01 DOI: 10.1155/crog/8743269

Matej Furlan, Miha Lučovnik, Nina Grasselli Kmet

{"title":"Herpes Simplex Virus 1 Encephalitis in First Trimester of Pregnancy: A Case Report.","authors":"Matej Furlan, Miha Lučovnik, Nina Grasselli Kmet","doi":"10.1155/crog/8743269","DOIUrl":"https://doi.org/10.1155/crog/8743269","url":null,"abstract":"Encephalitis caused by herpes simplex virus 1 (HSV-1) has been described in pregnancy, but it's rare, with less than 20 cases being described in peer-reviewed literature. Physiologic changes in immune response during pregnancy influence the course of HSV-1 encephalitis (HSVE) and predispose pregnant women to severe complications. We present a case of herpetic encephalitis in a 12-weeks pregnant patient. In our patient neurologic condition deteriorated despite early diagnosis, appropriate antiviral and antiepileptic treatment, and suppurative neurocritical care, respectively. Disease progression stopped and the patient's condition improved after pregnancy termination. Improvement could be a consequence of multiple factors, including delayed therapeutic effect of antiviral treatment, the impact of intensive care management, seizure control, and the possibility of spontaneous recovery as part of the natural disease course, respectively. This case highlights the potential severity of HSV-1 in early pregnancy and underscores the importance of multidisciplinary management and individualized decision-making in complex clinical situations.","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8743269"},"PeriodicalIF":0.8,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13060632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147643925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0