Case Reports in Obstetrics and Gynecology最新文献

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A Case of Undifferentiated Carcinoma in a 2-Month Postpartum Reproductive Tract with a Rapid and Fulminant Course. 产后2月生殖道未分化癌1例,病程急发。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-10-19 eCollection Date: 2021-01-01 DOI: 10.1155/2021/3516646
Yasuhiro Yokoyama, Mariko Suzuki, Yasumasa Sato, Shegenori Iwagaki, Yuichiro Takahashi, Hitoshi Iwata
{"title":"A Case of Undifferentiated Carcinoma in a 2-Month Postpartum Reproductive Tract with a Rapid and Fulminant Course.","authors":"Yasuhiro Yokoyama,&nbsp;Mariko Suzuki,&nbsp;Yasumasa Sato,&nbsp;Shegenori Iwagaki,&nbsp;Yuichiro Takahashi,&nbsp;Hitoshi Iwata","doi":"10.1155/2021/3516646","DOIUrl":"https://doi.org/10.1155/2021/3516646","url":null,"abstract":"<p><p>Advanced carcinoma of the lower female reproductive tract is rare during pregnancy and the postpartum period. We here present a case of a 32-year-old Japanese woman, whose entire lower reproductive tract had been invaded by carcinomas as of 2 months after childbirth. She had been infertile, and pregnancy had been established by repeated embryo transfer. The gynecological cancer screening, which included Pap smear tests, was negative during the periods she underwent infertility treatment or during the first trimester. At 26 gestational weeks, the patient noticed uterine contractions concomitant with genital bleeding. Labor progressed slowly and steadily; thus, the pregnancy was ended by cesarean section at 29 weeks. At 2 months after childbirth, the patient experienced increased left abdominal pain and underwent a pelvic examination, revealing multiple pelvic masses and diffuse vaginal tumors causing stenosis. Vaginal tumors were biopsied, and histochemical analysis showed undifferentiated carcinoma with possible adenocarcinoma. Imaging modalities including CT, MRI, and PET-CT suggest that the carcinoma had invaded the entire reproductive tract, especially the uterine body, metastasized into the lungs and the ischial bones, and disseminated onto the peritoneum. She received multiple rounds of chemotherapy but died 6 months after childbirth. Taking into consideration the clinical feature and immunohistochemical profiles of the cancer cells, the endometrium is the most likely origin.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"3516646"},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39660570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Primary Fallopian Tube Cancer in an 89-Year-Old Patient. 89岁原发性输卵管癌一例。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-10-08 eCollection Date: 2021-01-01 DOI: 10.1155/2021/2870057
Emmanuel N Kontomanolis, Antonios Koutras, Thomas Ntounis, Michail Diakosavvas, Kyveli Angelou, Athina A Samara, Themistoklis Grigoriadis, Pelagia Kadari, Ioannis Tsirkas, Marianna Theodora, Zacharias Fasoulakis
{"title":"Primary Fallopian Tube Cancer in an 89-Year-Old Patient.","authors":"Emmanuel N Kontomanolis,&nbsp;Antonios Koutras,&nbsp;Thomas Ntounis,&nbsp;Michail Diakosavvas,&nbsp;Kyveli Angelou,&nbsp;Athina A Samara,&nbsp;Themistoklis Grigoriadis,&nbsp;Pelagia Kadari,&nbsp;Ioannis Tsirkas,&nbsp;Marianna Theodora,&nbsp;Zacharias Fasoulakis","doi":"10.1155/2021/2870057","DOIUrl":"https://doi.org/10.1155/2021/2870057","url":null,"abstract":"<p><p>Fallopian tube cancer is an extremely rare gynecological condition, accounting for just 1 to 2% of all female tract malignancies. The mean age of diagnosis is similar to that of ovarian cancer, between 60 and 75 years, but it can affect a wide spectrum of ages. Advanced age and family history of ovarian and breast cancer are the main risk factors, since they are associated with increased incidence of this uncommon entity. In this study, we report a rare case of an elderly, 89-year-old patient that presented to our clinic due to vaginal bleeding.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"2870057"},"PeriodicalIF":0.0,"publicationDate":"2021-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39526285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Rare Disease Presenting Postpartum: Acute Fatty Liver of Pregnancy. 产后出现的罕见疾病:妊娠急性脂肪肝。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-30 eCollection Date: 2021-01-01 DOI: 10.1155/2021/1143470
Sofía Córdoba-Vives, Patricia Pérez-Rodríguez, Astrid Marín-Delgado, Miguel Matus-Vargas, Adriana Arias-González
{"title":"A Rare Disease Presenting Postpartum: Acute Fatty Liver of Pregnancy.","authors":"Sofía Córdoba-Vives, Patricia Pérez-Rodríguez, Astrid Marín-Delgado, Miguel Matus-Vargas, Adriana Arias-González","doi":"10.1155/2021/1143470","DOIUrl":"10.1155/2021/1143470","url":null,"abstract":"<p><p>Acute fatty liver of pregnancy is a rare but highly fatal disease affecting women most frequently during the third trimester of pregnancy or in the postpartum period. It is considered a diagnosis of exclusion and requires a timely diagnosis to avoid maternal mortality. We present the case of a 33-year-old primigravida who required an emergency cesarean section due to fetal bradycardia. On postoperative day one, the patient was noted jaundiced, oliguric, and hypoglycemic. Laboratory tests revealed important hepatic dysfunction, coagulopathy, and renal failure. She was admitted to the Intensive Care Unit with the suspicion of acute fatty liver of pregnancy. Plasma exchange was started on postoperative day 5 with major clinical and laboratory improvement. A transjugular hepatic biopsy confirmed the diagnosis. The patient had satisfactory evolution and was discharged 15 days after delivery. Acute fatty liver of pregnancy is a highly morbid disease that needs a high index of suspicion to be diagnosed. Admission to an Intensive Care Unit to ensure maximum supportive care is mandatory in this disease.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"1143470"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39505845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Ovarian Choriocarcinoma: Rare Entity. 原发性卵巢绒毛膜癌:罕见病例。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-24 eCollection Date: 2021-01-01 DOI: 10.1155/2021/4545375
Mequanent Tariku Adow, Shimelis Fantu Gebresilasie, Natnael Alemayehu Abebe
{"title":"Primary Ovarian Choriocarcinoma: Rare Entity.","authors":"Mequanent Tariku Adow,&nbsp;Shimelis Fantu Gebresilasie,&nbsp;Natnael Alemayehu Abebe","doi":"10.1155/2021/4545375","DOIUrl":"https://doi.org/10.1155/2021/4545375","url":null,"abstract":"<p><strong>Background: </strong>Primary pure ovarian choriocarcinoma is a rare aggressive tumor which can be nongestational arising from germ cells or gestational origin. Preoperative diagnosis of extrauterine choriocarcinoma is challenging due to nonspecific clinical presentation. <i>Case Presentation</i>. This article reports primary ovarian choriocarcinoma, likely gestational in a 25-year-old para 2 woman presenting with lower abdominal pain and swelling of two-week duration. Diagnosis was suspected by serum beta-human chorionic gonadotropin and confirmed histologically after surgery. Postoperatively, she was managed with multiple courses of chemotherapy using a bleomycin, etoposide, and cisplatin regimen, and the treatment was effective.</p><p><strong>Conclusion: </strong>In patients with adnexal mass presenting with nonspecific symptoms especially with high Doppler blood flow of the mass on ultrasound evaluation, serum beta-human chorionic gonadotropin determination is recommended before laparotomy. In setups where the genomic test is not available, histological and clinical effort to differentiate gestational versus nongestational choriocarcinoma is useful for specific management decision.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"4545375"},"PeriodicalIF":0.0,"publicationDate":"2021-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39485207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A Novel Use of Laryngoscope for Difficult Papanicolaou Smear Collection. 喉镜在困难的巴氏涂片采集中的新应用。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-23 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6986768
Sarah Boudova, Caitlin Thomas, John Wolfe, Jeanne M Schilder
{"title":"A Novel Use of Laryngoscope for Difficult Papanicolaou Smear Collection.","authors":"Sarah Boudova,&nbsp;Caitlin Thomas,&nbsp;John Wolfe,&nbsp;Jeanne M Schilder","doi":"10.1155/2021/6986768","DOIUrl":"https://doi.org/10.1155/2021/6986768","url":null,"abstract":"<p><p>The prevalence of cervical cancer has dropped significantly since introduction of the Papanicolaou (Pap) screen. The greatest risk factor for cervical cancer is inadequate screening. Altered pelvic anatomy can limit the ability to collect a Pap smear. In the presented case, a woman with a history of fibroids and bleeding presented for an exam under anesthesia. Traditional approaches for collecting a Pap smear failed. A GlideScope video laryngoscope was used to visualize the cervix, and a Pap smear was collected. The specimen was satisfactory, negative for intraepithelial lesion or malignancy, and HPV negative. A laryngoscope can be repurposed to visualize collection of a challenging Pap smear. Novel approaches for Pap smear collection and cervical cancer screening are needed and have the potential to save lives.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"6986768"},"PeriodicalIF":0.0,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8486505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39482684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Omphalocele Secondary to Spontaneous Rupture of Allantoic Cyst in the Third Trimester of Pregnancy. 妊娠晚期尿囊囊肿自发性破裂继发于脐膨出。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-18 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6940685
Giuliana Orlandi, Paolo Toscano, Lavinia Di Meglio, Letizia Di Meglio, Aniello Di Meglio
{"title":"Omphalocele Secondary to Spontaneous Rupture of Allantoic Cyst in the Third Trimester of Pregnancy.","authors":"Giuliana Orlandi,&nbsp;Paolo Toscano,&nbsp;Lavinia Di Meglio,&nbsp;Letizia Di Meglio,&nbsp;Aniello Di Meglio","doi":"10.1155/2021/6940685","DOIUrl":"10.1155/2021/6940685","url":null,"abstract":"<p><strong>Objective: </strong>We report the first case in which the onset of omphalocele was after the spontaneous rupture of an allantoic cyst. We hypothesize a causal link between the spontaneous rupture of the cyst and the herniation of the viscera. <i>Case Presentation</i>. A 36-year-old woman was diagnosed with an allantoic cyst during the first trimester. The allantoic cyst underwent spontaneous rupture during the 32nd week of gestation, and an omphalocele developed secondary to the cyst's rupture. Two days after birth, the peritoneum covering intestinal loops broke spontaneously and the newborn underwent successful urgent surgery.</p><p><strong>Conclusions: </strong>This case may suggest that the relative benignity of the allantoid cysts may recommend a close ultrasound follow-up in order to identify the onset of any complications, as a late third trimester onset of omphalocele. Prenatal diagnosis of such complications may allow multidisciplinary management of the pregnancy with planned cesarean section, prenatal pediatric surgery consultation, and neonatal surgery.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"6940685"},"PeriodicalIF":0.0,"publicationDate":"2021-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39470442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report of a Rare Nonpuerperal Uterine Inversion Managed with Uterosacral Ligament Hysteropexy. 子宫骶韧带子宫切除术治疗一例罕见的非产褥期子宫内翻。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-16 eCollection Date: 2021-01-01 DOI: 10.1155/2021/4054924
Ali Azadi, Alexandra Wolfe, Greg J Marchand
{"title":"Case Report of a Rare Nonpuerperal Uterine Inversion Managed with Uterosacral Ligament Hysteropexy.","authors":"Ali Azadi,&nbsp;Alexandra Wolfe,&nbsp;Greg J Marchand","doi":"10.1155/2021/4054924","DOIUrl":"https://doi.org/10.1155/2021/4054924","url":null,"abstract":"<p><p>Nonpuerperal uterine inversions are rare. Typically occurring in older women, they are most commonly due to transcervical mass expulsion. Diagnosis is often difficult because of vague symptomatology, presentation, and unknown course of the pathology. Surgical correction is often necessary in the presence of active bleeding or prolapse severity causing urinary retention. This case of nonpuerperal inversion presented to the emergency department with vaginal bleeding and mass protrusion. The examination was consistent with POPQ stage IV prolapse and uterine inversion secondary to cervical expulsion of multiple uterine fibroids. Because of full cervical dilation and concerns of ureteral injury with an extirpative procedure, vaginal myomectomy was performed with concomitant robotic uterosacral ligament hysteropexy. The operative procedure and postoperative course were uncomplicated, and discharge occurred on post-op day 1. She remained asymptomatic at the 6-month follow-up encounter. Though uterine preservation has been performed in cases of uterine inversion to maintain fertility, there are no reported cases of concomitant hysteropexy being completed for correction of POPQ stage IV prolapse simultaneously encountered. Additionally, the novel robotic approach has not been documented. This case illustrates the short-term success of robotic uterosacral hysteropexy as an additional option of care with potentially less morbidity when compared to hysterectomy for advanced stage uterine prolapse with nonpuerperal uterine inversion.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"4054924"},"PeriodicalIF":0.0,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39475407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Placenta Accreta Spectrum Disorder in a Patient with Six Previous Caesarean Deliveries: Step by Step Management. 6次剖宫产患者胎盘增生谱系障碍:分步处理。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-12 eCollection Date: 2021-01-01 DOI: 10.1155/2021/2105248
Calagna Gloria, Polito Salvatore, Labate Francesco, Guiglia Rosa Anna, De Maria Francesca, Bisso Chiara, Cucinella Gaspare, Calì Giuseppe
{"title":"Placenta Accreta Spectrum Disorder in a Patient with Six Previous Caesarean Deliveries: Step by Step Management.","authors":"Calagna Gloria,&nbsp;Polito Salvatore,&nbsp;Labate Francesco,&nbsp;Guiglia Rosa Anna,&nbsp;De Maria Francesca,&nbsp;Bisso Chiara,&nbsp;Cucinella Gaspare,&nbsp;Calì Giuseppe","doi":"10.1155/2021/2105248","DOIUrl":"https://doi.org/10.1155/2021/2105248","url":null,"abstract":"<p><p>The definition <i>placenta accreta spectrum disorders</i> (PAS) introduced by FIGO (International Federation of Gynaecology and Obstetrics) indicates an abnormal, pathological adherence or invasion of the placenta. The growing worldwide incidence of this pathological entity, and the possible serious correlated surgical risks, has caused a significant increase in attention among the scientific community. Previous caesarean delivery and presence of placenta previa are the main risk factors for the onset of PAS. Here, we present the intriguing case of a 39-year-old woman, at the 33rd week of gestation, with six previous caesarean sections and with a diagnosis of placenta previa accreta. At our referral center for PAS disorders, we successfully managed this difficult case with the help of a multidisciplinary skilled team.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"2105248"},"PeriodicalIF":0.0,"publicationDate":"2021-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39439691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Uterocutaneous Fistula after a C-Section in a Patient with Second Trimester Fetal Demise and Chorioamnionitis. 妊娠中期胎儿死亡和绒毛膜羊膜炎患者剖腹产后子宫皮瘘。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-10 eCollection Date: 2021-01-01 DOI: 10.1155/2021/3255188
Déborah Wernly, Valérie Besse, Daniela Huber
{"title":"Uterocutaneous Fistula after a C-Section in a Patient with Second Trimester Fetal Demise and Chorioamnionitis.","authors":"Déborah Wernly,&nbsp;Valérie Besse,&nbsp;Daniela Huber","doi":"10.1155/2021/3255188","DOIUrl":"https://doi.org/10.1155/2021/3255188","url":null,"abstract":"<p><p>Uterocutaneous fistulae are very rare entities with only about 120 cases reported in the literature. They are mostly described after a C-section or other pelvic surgery. We hereby describe a uterocutaneous fistula in a 41-year-old patient 5 months after a C-section because of a chorioamnionitis and a 22-week fetal demise. One month after the C-section, she underwent a diagnostic hysteroscopy to exclude postoperative intrauterine adhesions. Afterwards, she complained of pelvic pain, persistent metrorrhagia, and significant weight loss during 2 months. She consulted the emergency unit several times, and lastly endometritis was diagnosed. She was treated with antibiotic therapy for 7 days, without significant clinical improvement. She presented at our institution 48 hours after a carbuncle had appeared in her right iliac fossa. A uterocutaneous fistula was diagnosed on the CT scan. The patient received IV antibiotic therapy and underwent a total hysterectomy with bilateral salpingectomy by laparotomy, as she did not want a conservative surgery. The clinical postoperative evolution was favorable. Symptoms of UCF can be very unspecific. To avoid medical wandering and improve the patient's care, UCF should be in the differential diagnostic of abdominal pain after a pelvic surgery. Moreover, in patients with previous C-section and infectious perioperative status, the risk of PID or pelvic abscess must be careful evaluated before intrauterine diagnostic or therapeutic procedures.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"3255188"},"PeriodicalIF":0.0,"publicationDate":"2021-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39434601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Hyperbaric Oxygen Therapy for Suburethral Vaginal Mucosal Necrosis after Interstitial Irradiation for Recurrent Cervical Cancer. 高压氧治疗复发性子宫颈癌间质照射后阴道黏膜坏死。
Case Reports in Obstetrics and Gynecology Pub Date : 2021-09-09 eCollection Date: 2021-01-01 DOI: 10.1155/2021/1737975
Yoshihisa Arakaki, Yuko Shimoji, Tadaharu Nakasone, Yusuke Taira, Tomoko Nakamoto, Wataru Kudaka, Keiko Mekaru, Yoichi Aoki
{"title":"Hyperbaric Oxygen Therapy for Suburethral Vaginal Mucosal Necrosis after Interstitial Irradiation for Recurrent Cervical Cancer.","authors":"Yoshihisa Arakaki,&nbsp;Yuko Shimoji,&nbsp;Tadaharu Nakasone,&nbsp;Yusuke Taira,&nbsp;Tomoko Nakamoto,&nbsp;Wataru Kudaka,&nbsp;Keiko Mekaru,&nbsp;Yoichi Aoki","doi":"10.1155/2021/1737975","DOIUrl":"https://doi.org/10.1155/2021/1737975","url":null,"abstract":"<p><p>Patients with gynecological malignancies can develop radiation injuries, such as cystitis, proctitis, and soft tissue necrosis which have approved indications for hyperbaric oxygen therapy (HBOT). A 76-year-old Japanese woman with vaginal recurrence of cervical cancer was treated with the high-dose rate interstitial brachytherapy. Twenty-one months after the irradiation, she developed radiation necrosis on the external urethral opening. Two cycles of HBOT were performed. HBOT consisted of delivering 100% oxygen for 60 minutes at 2.4 atmospheres absolute. Pressure exposure was performed once daily, 5 days a week for 6 weeks. Eventually, the necrotic mucosa was completely replaced by the normal mucosa. No adverse effects were observed. We successfully treated a case of late adverse events of radiation therapy with HBOT. It was noninvasive and appears to be a useful treatment option which should be considered standard treatment practice.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2021 ","pages":"1737975"},"PeriodicalIF":0.0,"publicationDate":"2021-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39432936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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