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Spontaneous Heterotopic Pregnancy: Diagnosis and Management. 自发性异位妊娠:诊断与处理。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-26 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2994808
Katie P Nguyen, Marlekah Hudspeth, Honey Milestone
{"title":"Spontaneous Heterotopic Pregnancy: Diagnosis and Management.","authors":"Katie P Nguyen,&nbsp;Marlekah Hudspeth,&nbsp;Honey Milestone","doi":"10.1155/2022/2994808","DOIUrl":"https://doi.org/10.1155/2022/2994808","url":null,"abstract":"<p><strong>Background: </strong>Heterotopic pregnancies albeit rare are conceivably life-threatening if missed. With the development of assisted reproductive techniques, the incidence has increased. Confirmation of an intrauterine pregnancy (IUP) should not preclude the existence of a heterotopic pregnancy.</p><p><strong>Case: </strong>A healthy 27-year-old patient (gravida 4, term 1, preterm 0, abortion 2, living 1) at approximately 5 weeks gestation through natural conception presented to the emergency room with acute abdominal pain and vaginal bleeding. Pelvic ultrasound showed evidence of an IUP and a right adnexal mass, raising suspicion for a heterotopic pregnancy. The patient underwent an uncomplicated laparoscopic right salpingectomy. An IUP was confirmed on ultrasound postoperatively. The patient had an early pregnancy loss at 8 weeks of gestation.</p><p><strong>Conclusion: </strong>With a high index of suspicion from clinical presentation and pelvic imaging, heterotopic pregnancy, while rare, should not be ruled out.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"2994808"},"PeriodicalIF":0.0,"publicationDate":"2022-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rhabdomyosarcoma-Induced Uterine Inversion. 横纹肌肉瘤所致子宫内翻。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-23 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1361803
Kin Li, Gavin Davis, Colleen Wittenberg, Alireza Abidi
{"title":"Rhabdomyosarcoma-Induced Uterine Inversion.","authors":"Kin Li,&nbsp;Gavin Davis,&nbsp;Colleen Wittenberg,&nbsp;Alireza Abidi","doi":"10.1155/2022/1361803","DOIUrl":"https://doi.org/10.1155/2022/1361803","url":null,"abstract":"<p><p>Nonpuerperal uterine inversion is a rare clinical condition that involves prolapse of the uterine fundus into the uterine cavity and vaginal vault and possibly passed the introitus. The majority of these cases commonly involve benign tumors such as leiomyoma. However, another common cause of nonpuerperal uterine inversion is due to malignancies such as sarcomas. Rhabdomyosarcoma is a rare and aggressive malignancy of soft tissue cells that are common in children and rare in adults. One subtype called embryonal rhabdomyosarcoma is exceptionally rare. Therefore, report of embryonal rhabdomyosarcoma-induced uterine inversion is an exceedingly scarce and rarely documented clinical condition. In this case report, we present a rare case of a nulliparous 27-year-old female who presented with embryonal rhabdomyosarcoma-induced uterine inversion.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"1361803"},"PeriodicalIF":0.0,"publicationDate":"2022-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40576465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Delayed Interval Delivery in Preterm Premature Rupture of Membranes in Dichorionic Triamniotic Triplets: Ethical Considerations for Maternal Health Case Report. 双绒毛膜三羊膜三胞胎的胎膜早破:对孕产妇健康的伦理考虑
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-21 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4766523
Ali Hosiani, James Brown, Indika T Alahakoon
{"title":"Delayed Interval Delivery in Preterm Premature Rupture of Membranes in Dichorionic Triamniotic Triplets: Ethical Considerations for Maternal Health Case Report.","authors":"Ali Hosiani,&nbsp;James Brown,&nbsp;Indika T Alahakoon","doi":"10.1155/2022/4766523","DOIUrl":"https://doi.org/10.1155/2022/4766523","url":null,"abstract":"<p><strong>Background: </strong>Although there are numerous studies on delayed interval delivery in twins, this study is one of few reporting on preterm premature rupture of membranes in triplets and even fewer on dichorionic triamniotic triplet twins. The case presented here highlights the important interplay between informed consent and patient autonomy. <i>Case Presentation</i>. A 37-year-old woman gravida 1, para 0 with a dichorionic triamniotic triplet pregnancy experienced preterm premature rupture of membranes of the singleton triplet at 15 weeks and six days of gestation. Delayed interval delivery was offered to the parents, who chose to continue the pregnancy while acknowledging the risks for maternal and foetal health. The patient was treated with prophylactic intravenous antibiotics and discharged on oral antibiotics after an eight-day admission. Two days after being discharged, she was readmitted with clinical signs of chorioamnionitis. Within six hours, the preterm premature rupture of membranes singleton was delivered. Three days later, she again presented to the hospital with preterm premature rupture of membranes of one of the dichorionic twins. After discussion with the maternal foetal medicine team, the parents chose to terminate the pregnancy. Delayed interval delivery was not successful in this patient, and it is unclear at which gestational age it is too early to offer expectant management.</p><p><strong>Conclusions: </strong>The case affirmed the very poor foetal survival rate when the first delivery occurs at under 20 weeks' gestation. A standardised management of delayed interval delivery should be established to assist with consistent parental counselling.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"4766523"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40658127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Paraurethral Aggressive (Deep) Angiomyxoma. 尿道旁侵袭性(深部)血管粘液瘤。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-20 eCollection Date: 2022-01-01 DOI: 10.1155/2022/5604460
Daniel York, Smera Saikumar, Pavan Patel, Christian Edwards, Geossette Garcia, Hyder Naqvi
{"title":"A Paraurethral Aggressive (Deep) Angiomyxoma.","authors":"Daniel York,&nbsp;Smera Saikumar,&nbsp;Pavan Patel,&nbsp;Christian Edwards,&nbsp;Geossette Garcia,&nbsp;Hyder Naqvi","doi":"10.1155/2022/5604460","DOIUrl":"https://doi.org/10.1155/2022/5604460","url":null,"abstract":"<p><strong>Background: </strong>Aggressive angiomyxomas (AAs) are rare mesenchymal tumors that are histologically composed of myxoid stroma and vasculature. AAs are typically located in the pelvis and perineum and occur more frequently in females of reproductive age. <i>Case Presentation</i>. In this report, we outline a patient who had a paraurethral tumor with histopathology showing a circumscribed hypocellular lesion with myxoid stroma and abundant vasculature, consistent with the diagnosis of aggressive angiomyxoma. The mass was excised with resolution of symptoms and the patient was advised to continue close follow-up with her gynecologist and endocrinologist to monitor for recurrence.</p><p><strong>Conclusion: </strong>Due to its rarity, aggressive angiomyxomas are often misdiagnosed as cysts, hernias, lipomas, or cancerous lesions. Although benign, close follow-ups are crucial to monitor for recurrences or metastasis.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"5604460"},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40660242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Pregnancy Outcome and Postnatal Chromosome Analysis of the Cord Blood and Chorionic Villi in Two Cases after Intrauterine Transfer of Mosaic Aneuploid Blastocysts. 2例嵌合非整倍体囊胚宫内移植后脐带血和绒毛膜绒毛的妊娠结局及产后染色体分析。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-19 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1763948
Yuki Ito, Taizan Kamide, Kosuke Taniguchi, Taisuke Sato, Michihiro Yamamura, Akiko Konishi, Ken Takahashi, Hiroshi Kishi, Kenichiro Hata, Osamu Samura, Aikou Okamoto
{"title":"Pregnancy Outcome and Postnatal Chromosome Analysis of the Cord Blood and Chorionic Villi in Two Cases after Intrauterine Transfer of Mosaic Aneuploid Blastocysts.","authors":"Yuki Ito,&nbsp;Taizan Kamide,&nbsp;Kosuke Taniguchi,&nbsp;Taisuke Sato,&nbsp;Michihiro Yamamura,&nbsp;Akiko Konishi,&nbsp;Ken Takahashi,&nbsp;Hiroshi Kishi,&nbsp;Kenichiro Hata,&nbsp;Osamu Samura,&nbsp;Aikou Okamoto","doi":"10.1155/2022/1763948","DOIUrl":"https://doi.org/10.1155/2022/1763948","url":null,"abstract":"<p><p>The long-term prognosis and genetic mechanism of pregnancy after intrauterine mosaic aneuploid blastocyst transfer remain unknown. We report the case of two babies after the aforementioned procedure and chromosomal analysis of their cord blood and chorionic villi. <i>Case Report 1</i>. A 41-year-old primipara, with two previous spontaneous abortions, was pregnant after intrauterine transfer of a blastocyst carrying 40% mosaicism of long-arm monosomy of chromosome 5. The amniocentesis results were 46,XX. A cesarean section was performed at 39 weeks. The female infant was 3,315 g at birth. <i>Case Report 2</i>. A 44-year-old primipara, with two spontaneous abortions, was pregnant after intrauterine transfer of a blastocyst carrying 40% mosaicism of long-arm monosomy of chromosome 9 and monosomy of chromosome 14. After genetic counselling, she decided not to undergo amniocentesis. No abnormalities were found by ultrasound. A cesarean section was performed at 38 weeks. The male infant was 3,340 g at birth. Chromosome analyses of postnatal cord blood and chorionic villi were performed using SNP arrays. The cord blood and chorionic villi showed no chromosomal structural abnormalities or mosaicism. For both, no disorders were observed at 10 months of age. We experienced the birth of babies after intrauterine transfer of mosaic aneuploid blastocysts.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"1763948"},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9325602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40660244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uterine Rupture in Pregnancy following Two Abdominal Myomectomies and IVF. 两次腹部子宫肌瘤切除术和体外受精后的妊娠子宫破裂。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-14 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6788992
Marco D'Asta, Ferdinando Antonio Gulino, Carla Ettore, Valentina Dilisi, Elisa Pappalardo, Giuseppe Ettore
{"title":"Uterine Rupture in Pregnancy following Two Abdominal Myomectomies and IVF.","authors":"Marco D'Asta,&nbsp;Ferdinando Antonio Gulino,&nbsp;Carla Ettore,&nbsp;Valentina Dilisi,&nbsp;Elisa Pappalardo,&nbsp;Giuseppe Ettore","doi":"10.1155/2022/6788992","DOIUrl":"https://doi.org/10.1155/2022/6788992","url":null,"abstract":"<p><strong>Objective: </strong>Uterine rupture (UR) during pregnancy is an obstetric emergency that could determine poor maternal and neonatal outcomes. There are many factors that could increase the risk of UR, such as a previous myomectomy. The aim of this study is to evaluate the role of a previous myomectomy in a spontaneous UR in pregnancy.</p><p><strong>Methods: </strong>A 33-year-old primigravida comes to our obstetric emergency room for pelvic pain at 29 weeks of gestation. In her medical history, there were two previous surgical operations of abdominal myomectomy, one in 2015 and one in January 2021 (6 months before conception). After 34 minutes, a pubo-subumbilical longitudinal laparotomy was performed for pathological decelerations in the cardiotocography. In the peritoneal cavity, there was 500 mL of blood serum liquid. The right arm and shoulder of the fetus were extending out of the uterus across a breach of 5 cm near the right tubal corner. A corporal incision was performed, and a healthy baby was born and moved to neonatal intensive unit care.</p><p><strong>Results: </strong>A UR can occur at any stage of pregnancy, mostly during the third trimester of pregnancy. Risk factors that increase the incidence of a uterine rupture after myomectomy include a short period (i.e., <12 months) between the myomectomy and conception, the opening of the endometrial cavity, and large myomas (with a maximum diameter above 4 cm). Uterine rupture during pregnancy after abdominal myomectomy seems to be less frequent than after a laparoscopic one.</p><p><strong>Conclusion: </strong>Uterine rupture is an obstetric emergency; it is mandatory to consider this eventuality in pregnancy, particularly in the third trimester, if there was a previous laparoscopic myomectomy in the anamnesis of the patient.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"6788992"},"PeriodicalIF":0.0,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40551360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Paratubal Cystectomy in a Pregnant Woman Using the Single-Incision Laparoscopic Surgery (SILS) Technique. 使用单切口腹腔镜手术(SILS)技术的孕妇输卵管旁膀胱切除术。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-14 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2802767
Luke William Nelson, Elliot MacKenzie
{"title":"Paratubal Cystectomy in a Pregnant Woman Using the Single-Incision Laparoscopic Surgery (SILS) Technique.","authors":"Luke William Nelson,&nbsp;Elliot MacKenzie","doi":"10.1155/2022/2802767","DOIUrl":"https://doi.org/10.1155/2022/2802767","url":null,"abstract":"<p><strong>Introduction: </strong>The proliferation of prenatal ultrasound has enhanced the detection of adnexal masses during pregnancy. The presentation necessitates a clear approach to investigation and treatment that balances both maternal and fetal risk. Laparoscopy is a safe approach to surgical management in the pregnant patient, and SILS may contribute to minimising perioperative complications. <i>Case Presentation</i>. We present the case of a 21-year-old female in her second trimester of pregnancy presenting with a large 20 cm right adnexal cyst. We proceeded with laparoscopic cystectomy via the SILS technique. There were no intraoperative complications, and she recovered well postoperatively.</p><p><strong>Conclusion: </strong>Laparoscopic resection of adnexal lesions is safe during pregnancy and should be favoured over the open approach. SILS minimises incision sites and has potential for reduction in perioperative morbidity.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"2802767"},"PeriodicalIF":0.0,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40551361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Case of a Large Extraovarian Endometrioma in an Adolescent. 青少年大卵巢外子宫内膜异位瘤1例。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-08 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1675353
Wei-Guo Nicholas Loh, Nira Borok, Lyndal Anderson, Tanushree Rao
{"title":"An Unusual Case of a Large Extraovarian Endometrioma in an Adolescent.","authors":"Wei-Guo Nicholas Loh,&nbsp;Nira Borok,&nbsp;Lyndal Anderson,&nbsp;Tanushree Rao","doi":"10.1155/2022/1675353","DOIUrl":"https://doi.org/10.1155/2022/1675353","url":null,"abstract":"<p><p>Endometriosis in adolescents is often underrecognized and is a contributing factor to significant delays in its diagnosis and management. Extraovarian endometrioma is uncommon, especially in the adolescent age range. We report on a rare case of a large extraovarian endometrioma involving the terminal ileum in an adolescent who presented with abdominal pain and a pelvic mass and its subsequent surgical management. It emphasizes the importance of having a broad differential diagnosis and considers endometriosis in any adolescent with pelvic pain and mass, especially in an atypical context. Increased awareness, education, and research on endometriosis in this young population are essential in order to overcome existing challenges in the early diagnosis and optimal management of this chronic gynaecological condition and avoid morbidity associated with advanced disease.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"1675353"},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40599355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression. HIV免疫抑制患者的疱疹病毒假瘤。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-07 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3109331
Daniel York, Pavan Patel, Smera Saikumar
{"title":"Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression.","authors":"Daniel York,&nbsp;Pavan Patel,&nbsp;Smera Saikumar","doi":"10.1155/2022/3109331","DOIUrl":"https://doi.org/10.1155/2022/3109331","url":null,"abstract":"<p><strong>Background: </strong>In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. <i>Case Presentation</i>. A 48-year-old patient presented with a large fungating mass near her right inferior vulva with a hardness of surrounding tissues. The mass was 4 cm × 3 cm in size and was excised in the operating room. The pathology was negative for malignancy; however, it showed lymphoplasmacytic proliferation with immunostaining positive for HSV virus.</p><p><strong>Conclusion: </strong>Atypical HSV pseudotumors should be considered in the differential diagnosis for an immunosuppressed patient who presents with a genital mass lesion.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"3109331"},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40601789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovarian Clear Cell Carcinoma with Functioning Stroma and Associated Endometrial Intraepithelial Neoplasia. 卵巢透明细胞癌伴功能性间质及相关子宫内膜上皮内瘤变。
Case Reports in Obstetrics and Gynecology Pub Date : 2022-07-06 eCollection Date: 2022-01-01 DOI: 10.1155/2022/5538390
Fabian Desimpel, Jean-Christophe Noël, Laurine Verset, Nicolas Sirtaine, Frédéric Buxant
{"title":"Ovarian Clear Cell Carcinoma with Functioning Stroma and Associated Endometrial Intraepithelial Neoplasia.","authors":"Fabian Desimpel,&nbsp;Jean-Christophe Noël,&nbsp;Laurine Verset,&nbsp;Nicolas Sirtaine,&nbsp;Frédéric Buxant","doi":"10.1155/2022/5538390","DOIUrl":"https://doi.org/10.1155/2022/5538390","url":null,"abstract":"<p><p>We report the case of a 79-year-old woman with a large pelvic mass and postmenopausal bleeding, associated with hyperestrogenism. A pelvic MRI shows the presence of a large mass of 12.6 cm originating from the right ovary without signs of metastasis. A total abdominal hysterectomy with unilateral salpingooophorectomy was performed, knowing the patient underwent a left salpingooophorectomy decades ago. The pathological findings showed an ovarian clear cell carcinoma (pT1A) with associated endometrial intraepithelial neoplasia. There is convincing evidence that the production of estrogen is located in the activated ovarian stroma. This supports the view that functioning stroma of ovarian cancer can lead to hyperestrogenism and eventually endometrial cancer.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":" ","pages":"5538390"},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40599356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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