Case Reports in Obstetrics and Gynecology最新文献

{"title":"Ovarian Yolk Sac Tumor in a 10-Year-Old Girl Following Metachronous Bilateral Mature Ovarian Teratomas.","authors":"Shiho Yoshida, Sakika Shimizu, Keisuke Kato, Geoffrey J Lane, Go Miyano, Toshihiro Yanai","doi":"10.1155/crog/9281498","DOIUrl":"https://doi.org/10.1155/crog/9281498","url":null,"abstract":"<p><strong>Background: </strong>Ovarian germ cell tumors are the most common ovarian malignancies in children. Because these patients have a notable risk of developing metachronous bilateral tumors or recurrences, maximizing the preservation of ovarian tissue during initial surgery is critical to protecting future fertility and endocrine function.</p><p><strong>Objective: </strong>A previously healthy 8-year-old girl underwent emergency laparotomy for ovarian torsion, resulting the right oophorectomy, with histopathology confirming a mature teratoma. Sixteen months later, a contralateral ovarian mass was detected and treated with ovarian-sparing excision, also diagnosed as a mature teratoma. At age 10 (10 months after the second excision), she was found to have an 8 cm pelvic tumor and elevated <i>α</i>-fetoprotein. Magnetic resonance imaging (MRI) showed complex solid and cystic components suggestive of a malignant germ cell tumor, with no metastases on computed tomography/MRI. The mass was removed intact at exploratory laparotomy, yielding a diagnosis of Fédération Internationale de Gynécologie et d'Obstétrique (FIGO) Stage 1A ovarian yolk sac tumor. She was discharged after completing combination chemotherapy. Currently, she is 16 years old and being managed with hormone replacement therapy.</p><p><strong>Conclusions: </strong>The presented case highlights a disadvantage of overzealous oophorectomy. Detorsion of the seemingly necrotic ovary followed by second-look surgery could have preserved some ovarian function.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"9281498"},"PeriodicalIF":0.8,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal Detection of <i>HSPG2</i>-Related Dyssegmental Dysplasia, Silverman-Handmaker Type: A Rare Case Report.","authors":"Omayyah Dar-Odeh, Raghad Abdeljawad, Rahaf Abdeljawad, Najla Dar-Odeh","doi":"10.1155/crog/5094018","DOIUrl":"10.1155/crog/5094018","url":null,"abstract":"<p><strong>Introduction: </strong><i>HSPG2</i>-related dyssegmental dysplasia (heparan sulfate proteoglycan 2) is an extremely rare and severe autosomal recessive skeletal dysplasia. The low incidence and the overlapping features with other types of lethal skeletal dysplasia represent the main challenges in diagnosis. Early diagnosis is essential and can be achieved by ultrasound examination and genetic analysis. This report describes a case of <i>HSPG2</i>-related dyssegmental dysplasia, Silverman-Handmaker type (DDSH) diagnosed prenatally through a combination of detailed ultrasound imaging and subsequent genetic analysis.</p><p><strong>Case presentation: </strong>A 21-year-old pregnant lady (G2P1) was referred to our center at 17-week gestation upon the detection of severe shortening of fetal limbs. Detailed ultrasound examination revealed small for gestational age, and specific craniofacial features such as severe micrognathia, short neck, microcephaly, prominent eyes, and occipital encephalocele. Other abnormalities were detected in extremities in the form of bowing of lower limbs, severe tetramicromelia, and upper limbs in a fixed flexion. Amniocentesis for whole exome sequencing was performed. It showed a homozygous pathogenic variant in the <i>HSPG2</i> gene (c.11565+1G>A), a result consistent with the genetic diagnosis of autosomal recessive <i>HSPG2</i>-related DDSH. Medical termination was performed based on the decision of parents. Parents signed a written consent for the publication of this case report.</p><p><strong>Discussion: </strong>Findings of this report support the growing evidence of the phenotypic spectrum and genetic underpinnings of the lethal disorder of <i>HSPG2</i>-related DDSH, emphasizing the importance of early and accurate diagnosis for optimal patient care. DDSH can be diagnosed prenatally using fetal ultrasound as early as 13 weeks. Radiographic assessment and molecular analysis of the <i>HSPG2</i> gene are essential for confirming the prenatal diagnosis. Accurate diagnosis enables appropriate healthcare delivery and facilitates informed reproductive decision-making, including prenatal diagnosis and preimplantation genetic testing in future pregnancies.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"5094018"},"PeriodicalIF":0.8,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI Imaging of Uterine Incarceration: From Diagnosis to Posttreatment Follow-Up.","authors":"Natália Henz Concatto, Ariane Giovanaz, Meiri Andreia Maria da Silva, Rubia Vanceta, Camila Braga Visconti, Adriana Prato Schmidt, Carolina Paz Mohamad Isa, Marcela Godoy Dias, Caroline Lorenzoni Almeida Ghezzi, Janete Vettorazzi, Cristiano Caetano Salazar","doi":"10.1155/crog/4993782","DOIUrl":"10.1155/crog/4993782","url":null,"abstract":"<p><strong>Introduction: </strong>Uterine incarceration is a rare and frequently underrecognized obstetric complication caused by persistent retroversion of the gravid uterus. Because clinical manifestations are often nonspecific, diagnosis may be delayed, increasing the risk of maternal and fetal complications. Imaging, particularly magnetic resonance imaging (MRI), may be essential when ultrasound findings are inconclusive.</p><p><strong>Case presentation: </strong>A 37-year-old multigravida with a history of recurrent pregnancy loss presented at 16 weeks' gestation with acute urinary retention. Clinical examination raised suspicion for uterine incarceration. MRI confirmed the diagnosis by demonstrating a retroverted gravid uterus impacted within the posterior pelvis, associated with elongation and anterior displacement of the cervix and compression of the lower urinary tract. Prompt bladder decompression and successful uterine repositioning were performed, with subsequent resolution of symptoms and favorable maternal-fetal evolution.</p><p><strong>Discussion: </strong>This case highlights the importance of correlating clinical and imaging findings in pregnant patients presenting with acute urinary symptoms. MRI was decisive in clarifying pelvic anatomy and establishing the diagnosis when sonographic evaluation was limited. Early recognition of uterine incarceration enables timely intervention and may reduce the risk of obstetric and urological complications, contributing to improved maternal-fetal monitoring and management.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"4993782"},"PeriodicalIF":0.8,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neural Tube Defects in Resource-Limited Settings: A Lebanese Case Series Highlighting Prevention Gaps and Challenges in Prenatal Diagnosis.","authors":"Georges Yared, Charlotte El Hajjar, Nidal Hammoud, Christopher Massaad, Kariman Ghazal","doi":"10.1155/crog/2044243","DOIUrl":"https://doi.org/10.1155/crog/2044243","url":null,"abstract":"<p><strong>Background: </strong>Neural tube defects (NTDs) are congenital developmental anomalies resulting from incomplete neural tube closure during early embryonic development. They present a wide range of clinical manifestations along the craniospinal axis.</p><p><strong>Objective: </strong>With only 6.2% of Lebanese women of childbearing age taking folic acid tablets during the adequate period, it is primordial to shed light on cases of NTDs in Lebanon. This case series presents four cases of NTDs that deviate from the conventional \"zipper closure\" model of neural tube development, aligning more with the modern multisite closure approach. This case series showcases the consequences of inadequate intake of folic acid prior to conception in addition to delayed prenatal diagnosis. The four cases are presented in accordance with CARE reporting guidelines.</p><p><strong>Methods: </strong>The study presents four case reports of NTDs, including iniencephaly, anencephaly, encephalocele, and spina bifida. Each case details the clinical presentation, diagnostic findings, and outcomes.</p><p><strong>Results: </strong>The cases demonstrate various manifestations of NTDs: (1) a case of iniencephaly with hydrocephalus and spina bifida in a 32-week fetus, (2) a case of anencephaly in a 34-week fetus, (3) a case of encephalocele in one fetus of diamniotic dichorionic twins at 37 weeks, and (4) a case of closed spina bifida diagnosed at 36 weeks.</p><p><strong>Discussion: </strong>The article explores the embryology, classification, and epidemiology of NTDs. It discusses factors that can contribute to NTDs. We also note the limited prenatal follow-up and care in vulnerable populations in Lebanon. Genetic and environmental factors are also discussed, with a particular focus on the role of folic acid and its metabolism.</p><p><strong>Conclusion: </strong>This case series highlights the diverse presentations of NTDs. It further showcases the importance of early diagnosis and management. It also emphasizes the need for folic acid supplementation and the consideration of multiple etiologies in the prevention and understanding of NTDs.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"2044243"},"PeriodicalIF":0.8,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hidden Hollows of the Fetal Cranium-Lacunar Skull in Isolation.","authors":"Grace Noonan, Lucy Sheahan, Mary Sterrett","doi":"10.1155/crog/8926011","DOIUrl":"https://doi.org/10.1155/crog/8926011","url":null,"abstract":"<p><strong>Introduction: </strong>Lacunar skull, also known as Lückenschädel or craniolacunae, is a rare congenital calvarial ossification abnormality characterized by multiple lucent defects of the skull. It is most associated with neural tube defects, Chiari II malformation, craniosynostosis, and other congenital anomalies. Isolated lacunar skull, without associated structural abnormalities, has been infrequently reported, and its natural history, prognosis, and optimal clinical management are poorly defined.</p><p><strong>Case presentation: </strong>We report the case of a female infant born at 38 weeks and 5 days' gestation to a 37-year-old gravida 6 para 3033 mother following an uncomplicated pregnancy. Prenatal genetic screening and serial fetal ultrasonography demonstrated no fetal anomalies, although a bilobed heterogeneous placenta was noted. Following an uncomplicated spontaneous vaginal delivery with Apgar scores of 8 and 9, a boggy right parietal scalp abnormality was identified on routine neonatal examination. Initial skull radiographs were inconclusive. Computed tomography (CT) with 3D reconstruction demonstrated multiple asymmetric lucent calvarial defects, more pronounced within the right parietal and occipital bones, consistent with lacunar skull. Brain parenchyma, ventricles, cranial sutures, and spine were normal. Additional evaluations revealed no associated abnormalities. Diagnostic genetic testing was deferred as no syndromic features or additional congenital anomalies were identified on evaluation. Conservative management with close clinical observation was recommended. At 6 weeks of age, the infant demonstrated normal neurological examination and age-appropriate developmental progress.</p><p><strong>Discussion: </strong>This case describes an uncommon presentation of isolated lacunar skull diagnosed postnatally in an otherwise healthy term infant with normal prenatal imaging. Unlike most reported cases, no associated central nervous system, skeletal, or syndromic abnormalities were identified following comprehensive evaluation. This report highlights the importance of distinguishing isolated lacunar skull from more common associated conditions, outlines an appropriate diagnostic evaluation, and supports conservative management with ongoing developmental surveillance in the absence of additional abnormalities.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8926011"},"PeriodicalIF":0.8,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13624703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149104758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Cases of Right-Sided Pleural Effusion as the Initial Manifestation of Severe Ovarian Hyperstimulation Syndrome.","authors":"Lonneke H C Gremmen, Hein Bogers, Catharina C M Beerendonk","doi":"10.1155/crog/6641371","DOIUrl":"10.1155/crog/6641371","url":null,"abstract":"<p><strong>Introduction: </strong>Severe ovarian hyperstimulation syndrome (OHSS) occurs less frequently due to increased knowledge of potential risk factors and implementation of preventive strategies. Right-sided pleural effusion as a presentation of severe OHSS is rare, and the symptoms can be nonspecific, which may delay diagnosis. However, early recognition is essential, as the condition can deteriorate rapidly and patients often need hospitalisation and supportive treatment.</p><p><strong>Case presentation: </strong>We describe two patients with right-sided pleural effusion as the initial manifestation of severe OHSS following controlled ovarian stimulation for in vitro fertilisation. Both patients reported sharp chest pain and progressive dyspnoea when the pleural effusion was diagnosed. They developed symptoms 5 and 13 days after oocyte pick-up (OPU) and were admitted to hospital 4 and 3 days after the onset of symptoms, respectively. The first patient required two paracenteses and one thoracentesis, and the second one thoracentesis. Supportive treatment during hospitalisation consisted of intravenous fluids, supplemental oxygen, electrolyte correction and thromboprophylaxis. The durations of hospitalisation were 12 and 2 days, respectively, and both patients recovered within 3 weeks after discharge.</p><p><strong>Conclusion: </strong>Right-sided pleural effusion may be the initial manifestation of severe OHSS. Although the exact pathogenesis remains unclear, several hypotheses have been proposed. We review the available evidence regarding its pathogenesis and therapeutic options, and highlight the importance of early recognition.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"6641371"},"PeriodicalIF":0.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Occurrence of Breast Cancer Metastases and Cervical Cancer Metastases in the Same Lymph Node.","authors":"Leonie-Sophia Pösch, Theodora Todorovic, Daniela Hagen, Gesine Meili","doi":"10.1155/crog/8810943","DOIUrl":"10.1155/crog/8810943","url":null,"abstract":"<p><strong>Background and aims: </strong>The simultaneous occurrence of different cancer types in the same individual is an uncommon event. We present a case of synchronous metastases of breast cancer and cervical cancer in the same lymph node in a patient with a history of cervical cancer with newly diagnosed breast cancer.</p><p><strong>Method: </strong>This article is a descriptive case report of a single patient treated at our institution. No statistical analysis was performed.</p><p><strong>Results: </strong>Following the recommendation of our interdisciplinary tumor conference, we began treatment with neoadjuvant chemotherapy in reverse order, with four cycles of carboplatin/Taxol (corresponding to first-line chemotherapy for cervical cancer), followed by four cycles of EC (epirubicin and cyclophosphamide) (corresponding to first-line chemotherapy for breast cancer), mammoplasty, and adjuvant radiotherapy, including internal mammary and supraclavicular node irradiation. By adjusting therapy regimens, it was possible to achieve complete remission of both the primary and secondary tumors.</p><p><strong>Conclusion: </strong>The occurrence of synchronous cervical and breast cancer is extremely rare, with only a few cases reported in the literature. A definitive correlation between the two cancers cannot currently be established due to limited cases. Because of this rarity, treatment planning is particularly complex and requires an individualized, multidisciplinary approach. A combination of systemic therapy, radiotherapy, and surgery may achieve complete remission in selected patients, as we saw in our case. Mortality rates remain unclear due to the limited number of reported cases.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"8810943"},"PeriodicalIF":0.8,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13594382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of an Advanced Low-Lying Implantation Disorder With Cervico-Isthmic Features at 29 Weeks of Gestation Presenting With PPROM: A Case Report and Literature Review.","authors":"Nafiseh Saedi, Azita Zare, Sara Ashtari, Nooshin Faraji, Fatemeh Golshahi, Behrokh Sahebdel, Elham Shirali, Sara Parviz, Mohammad M Mehrabi","doi":"10.1155/crog/9537307","DOIUrl":"10.1155/crog/9537307","url":null,"abstract":"<p><strong>Introduction: </strong>Cervico-isthmic pregnancy (CIP) is a rare form of low-lying implantation in which the gestational sac implants between the anatomical and histological internal os. It is associated with significant maternal morbidity due to abnormal placentation and a high risk of placenta accreta spectrum (PAS). Advanced cases beyond 20 weeks are exceedingly rare and pose major diagnostic and surgical challenges.</p><p><strong>Case presentation: </strong>A 30-year-old woman, gravida 2, para 1, with a history of prior cesarean section and Asherman syndrome, presented at 28 weeks and 4 days of gestation with preterm premature rupture of membranes. An ultrasound revealed a viable breech fetus located in the lower uterine segment and cervico-isthmic region. The presence of placental lacunae and bridging vessels suggested PAS. An MRI confirmed significant thinning of the lower uterine segment, nearly complete loss of myometrial tissue, and a preserved endocervical canal, consistent with CIP and PAS. Because of the high risk of hemorrhage, a cesarean section was performed using a posterior uterine incision, followed by immediate hysterectomy due to massive bleeding. Histopathological analysis confirmed the diagnosis of placenta increta in the cervico-isthmic area. Both maternal recovery and neonatal outcomes were favorable.</p><p><strong>Discussion: </strong>This case highlights the diagnostic difficulty of advanced low-lying implantation disorders with features favoring CIP. In late gestation, the anatomic boundaries among CIP, cervical pregnancy, and endogenic/Type I CSP may become difficult to define because the implantation site can expand beyond its original location. Careful evaluation of placental topography using ultrasound and MRI, supported by intraoperative anatomic findings and histopathologic correlation, can help characterize the implantation site and guide diagnostic interpretation. Nevertheless, even with multimodal assessment, overlap between CIP and endogenic/Type I CSP may persist, and definitive classification may remain challenging.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"9537307"},"PeriodicalIF":0.8,"publicationDate":"2026-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13591125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149015615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three Concurrent Nonpalpable Nexplanon Implants in the Upper Arms Following Presumed Failed Insertions: A Case Report.","authors":"Alexia Barrios, Kyara M Marquez, Austin Zanelotti, Ian J Bishop","doi":"10.1155/crog/2797689","DOIUrl":"10.1155/crog/2797689","url":null,"abstract":"<p><strong>Introduction: </strong>Subdermal etonogestrel implants (Nexplanon) are a widely used form of long-acting reversible contraception, providing up to 5 years of pregnancy prevention. Their ease of outpatient insertion and high efficacy have contributed to their widespread use. However, correct subdermal placement and immediate postinsertion confirmation of palpability are essential to ensure proper positioning and facilitate future localization and removal.</p><p><strong>Case presentation: </strong>We report the case of a 42-year-old G1P1001 patient who was ultimately found to have three nonpalpable concurrent Nexplanon implants in both upper arms following multiple presumed failed insertion attempts over several years. On several occasions, newly placed implants were not palpable after insertion and were assumed to represent failed deployment, leading to repeat insertions without imaging confirmation. At presentation to our institution, high-frequency ultrasound identified a total of three nonpalpable, but superfascial, implants: two in the left upper arm and one in the right upper arm. All devices were successfully localized and removed in an outpatient setting using ultrasound-guided techniques without complication.</p><p><strong>Discussion: </strong>Nonpalpable contraceptive implants most commonly result from deep insertion into subcutaneous, fascial, or intramuscular tissue. Most published reports describe single retained implants managed with high-frequency ultrasound as the first-line modality for localization and removal. This case is unique in demonstrating the cumulative consequence of repeated misinterpretation of nonpalpability as failed insertion, resulting in multiple retained devices across both upper arms. It highlights a critical gap in procedural verification and reinforces the importance of standardized postinsertion confirmation protocols.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"2797689"},"PeriodicalIF":0.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13584329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148988247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Metastatic Involvement of the Sigmoid Mesocolon by Low-Grade Endometrial Stromal Sarcoma.","authors":"Niloufar Ahmadloo, Susan Andalibi, Ahmad Mosalaei, Shapour Omidvari, Mansour Ansari, Heshmatollah Salahi, Nazanin Karamifar, Ehsan Mohammad Hosseini","doi":"10.1155/crog/4460648","DOIUrl":"10.1155/crog/4460648","url":null,"abstract":"<p><strong>Introduction: </strong>Endometrial stromal sarcoma (ESS) is an uncommon uterine malignancy with an indolent course and potential for late recurrence or metastasis. Extrauterine ESS is exceedingly rare, especially in the absence of a primary uterine lesion.</p><p><strong>Case presentation: </strong>We present a case of a 50-year-old woman with low-grade ESS metastasizing to the sigmoid mesocolon. The patient underwent surgical resection followed by radical hysterectomy, bilateral salpingo-oophorectomy, and hormonal therapy with letrozole. After 5 years of follow-up, she remains disease-free.</p><p><strong>Discussion: </strong>This case underscores the importance of considering ESS in the differential diagnosis of mesocolon masses and highlights the role of combined surgical and hormonal therapy in achieving long-term remission.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2026 ","pages":"4460648"},"PeriodicalIF":0.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}