Muhammad Dwi Priangga, Adhitya Yudha Maulana, Yasmine Syifa Nabila Budi, Syauqi Maulana Idhar, Herbert Situmorang
{"title":"Silent Threat: Bilateral Giant Asymptomatic Endometriotic Cysts With Unilateral Sudden Rupture-A Case Report.","authors":"Muhammad Dwi Priangga, Adhitya Yudha Maulana, Yasmine Syifa Nabila Budi, Syauqi Maulana Idhar, Herbert Situmorang","doi":"10.1155/crog/1739044","DOIUrl":"10.1155/crog/1739044","url":null,"abstract":"<p><p>Endometriotic cysts are common, but bilateral giant endometriosis cyst with asymptomatic cases are extremely rare. Rupture is also uncommon, yet when it occurs, it can mimic appendicitis or ectopic pregnancy due to peritoneal irritation, often requiring emergency intervention. A 25-year-old woman presented with nausea, vomiting, and an enlarging abdominal lump. Ultrasonography revealed bilateral ovarian cystic masses with ground glass appearances and free subhepatic fluid. Due to worsening symptoms despite initial resuscitation, emergency exploratory laparotomy was performed. Intraoperatively, a ruptured right ovarian cyst (20 × 15 × 15 cm) with extensive adhesions to the posterior uterus, rectum, and right ovarian fossa was identified, along with a left ovarian endometriotic cyst (12 × 10 × 10 cm). The patient underwent right salpingo-oophorectomy, left cystectomy, and ureterolysis. Histopathology confirmed endometriotic cysts. Rapid surgical intervention is crucial in ruptured cysts to minimize adhesion formation and preserve fertility. Postoperatively, continuous hormonal therapy, such as oral progesterone or an intrauterine device, is recommended to decrease recurrence.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"1739044"},"PeriodicalIF":0.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12221541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha Kegel, Meena Dhir, Karina Hew, Chanda Reese, Gregory Lewis
{"title":"A Rare Case of a Hypervascular Placental Polyp Leading to Massive Postpartum Hemorrhage Requiring Hysterectomy.","authors":"Samantha Kegel, Meena Dhir, Karina Hew, Chanda Reese, Gregory Lewis","doi":"10.1155/crog/4120029","DOIUrl":"10.1155/crog/4120029","url":null,"abstract":"<p><p>A placental polyp is a retained fragment of placental tissue that can lead to postpartum hemorrhage or become a nidus for infection. Hypervascular placental polyps can pose an increased risk of life-threatening postpartum hemorrhage requiring immediate intervention. Thus, prompt recognition and appropriate management are crucial in preventing maternal morbidity and mortality. Here, we present the case of a 29-year-old patient who had a spontaneous vaginal delivery at 36-week gestation after induction of labor due to pre-eclampsia with severe features. Quantitative blood loss at delivery was 1300 mL, and the patient received uterotonic medications. Due to continued bleeding, she underwent a suction curettage with clots and retained tissue removed from the uterine fundus. The total blood loss was estimated to be 4 L, and the massive transfusion protocol was activated. On postpartum Day 1, she underwent a bilateral uterine artery embolization; however, she developed further heavy vaginal bleeding. A second suction curettage was performed after ultrasound showed hypervascular material in the uterine cavity. The patient was subsequently discharged, but represented on postpartum Day 15 with increased bleeding. Imaging again demonstrated a hypervascular intrauterine polypoid mass. The patient desired definitive management and underwent a minimally invasive total hysterectomy.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"4120029"},"PeriodicalIF":0.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12221538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lubos Karasek, Pavla Svobodova, Imrich Kiss, Jan Smetana
{"title":"Recurrent Pelvic Inflammatory Disease After Serial Intrauterine Inseminations.","authors":"Lubos Karasek, Pavla Svobodova, Imrich Kiss, Jan Smetana","doi":"10.1155/crog/1426202","DOIUrl":"10.1155/crog/1426202","url":null,"abstract":"<p><p><b>Introduction:</b> Intrauterine insemination is a basic method of assisted reproduction. It enables direct deposition of sperm inside the uterine cavity. The complications are rare. Multiple pregnancy or ovarian hyperstimulation can occur when concomitant ovulation induction is performed. The risk of pelvic inflammatory disease due to the artificial cervical barrier breach is very low, but the possible consequences are serious. <b>Case presentation:</b> We present a case of recurrent pelvic inflammatory disease following consecutive intrauterine inseminations. Pelvic inflammatory disease pathophysiology and treatment approaches are discussed. <b>Conclusion:</b> Inflammatory complications of the IUI are rare, but the possible impact on fertility can be devastating. Prevention of the PID together with prompt diagnosis and individualized therapy should be assured to preserve fertility.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"1426202"},"PeriodicalIF":0.6,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12206568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Judy Hayek, Mariem Del Rio, Yongmei Yin, Margaux J Kanis
{"title":"Primary Squamous Cell Carcinoma of the Uterus and Not the Cervix-A Case Report and Literature Review.","authors":"Judy Hayek, Mariem Del Rio, Yongmei Yin, Margaux J Kanis","doi":"10.1155/crog/7140494","DOIUrl":"10.1155/crog/7140494","url":null,"abstract":"<p><p>Primary endometrial squamous cell carcinoma (PESCC) is a rare pathology. Data regarding diagnosis and treatment is limited and is solely based on case reports and series. We report a unique case of a postmenopausal woman with a history of HIV and anal cancer s/p radiation therapy 8 years prior. The patient's presenting diagnosis was malodorous vaginal discharge refractory to antibiotics. The patient had a significant delay in diagnosis since the onset of symptoms despite extensive workup but eventually underwent surgical staging by gynecologic oncology with a diagnosis of Stage IB PESCC. Despite her reported history of anal cancer for which she received an incomplete course of pelvic radiation, the case was discussed at tumor board and the patient was deemed a candidate for external beam radiation therapy. In our report, we discuss, in detail, the patient's presentation, course, and treatment and review the literature.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"7140494"},"PeriodicalIF":0.6,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transvesical Laparoscopic Mesh Excision After Tension-Free Vaginal Tape.","authors":"Camille Farache, Peter Fehr","doi":"10.1155/crog/8824103","DOIUrl":"10.1155/crog/8824103","url":null,"abstract":"<p><p>Tension-free vaginal tape has been the gold standard for the treatment of stress urinary incontinence for over 20 years. However, rare complications like intravesical tape erosion can significantly reduce quality of life, requiring surgical removal. This procedure must preserve continence and can be challenging. We report the case of a 53-year-old woman who presented with recurrent urinary tract infections and dysuria 7 years after a TVT procedure. Imaging revealed a bladder stone attached to the eroded sling at the bladder neck, inaccessible via standard cystoscopy. A transvesical laparoscopic approach was used to successfully remove the intravesical portion of the tape. The patient recovered well and remained symptom-free and continent. Various techniques are used to perform intravesical tape resection. Transvesical laparoscopy offers excellent visualization and precise excision and minimizes recurrence risks for stress urinary incontinence. It is a safe, effective, and minimally invasive option for removing eroded tension-free vaginal tape, especially in difficult-to-access areas like the bladder neck.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"8824103"},"PeriodicalIF":0.6,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144474003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha Metzger, Keely Ulmer, Erik Arneson, Christine Gill, Michael J Goodheart
{"title":"Anti-NMDA Receptor Encephalitis in the Setting of an Immature Ovarian Teratoma: A Case Report and Literature Review.","authors":"Samantha Metzger, Keely Ulmer, Erik Arneson, Christine Gill, Michael J Goodheart","doi":"10.1155/crog/9923415","DOIUrl":"10.1155/crog/9923415","url":null,"abstract":"<p><p>We report a case of a 19-year-old diagnosed with anti-NMDAR encephalitis in relation to an immature ovarian teratoma. Ultimately, chemotherapy resulted in her improvement despite poor performance status. We provide a literature review of the published cases of anti-NMDAR encephalitis caused by immature teratomas and summarize their treatment.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"9923415"},"PeriodicalIF":0.6,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Two-Step Parametrial Endometriosis Nodule Excision Using Virtual Reality Technology and 3D Modelling for Surgical Planning.","authors":"Rooma Sinha, Sukhbir Singh, Teresa Flaxman","doi":"10.1155/crog/5513823","DOIUrl":"10.1155/crog/5513823","url":null,"abstract":"<p><p>Extensive and infiltrative fibrous adhesions of the uterus and ovaries to the surrounding organs make surgical interventions in endometriosis challenging. A preoperative identification of these involvements can help the surgeon better prepare for the surgery. Traditionally, ultrasonography and magnetic resonance imaging (MRI) have been used. However, clinical use of modern VR technology for creating and visualising a three-dimensional (3D) digital model for a complex surgical case has been proposed. We describe a case of a 29-year-old who presented with dyspareunia and dysmenorrhea (VAS score of 10/10) with left parametrial endometriosis and created a 3D model from their two-dimensional (2D) DICOM images. A left parametrial endometriosis nodule was identified involving the left ureter, rectum, and vaginal fornix along with mucosa. A virtual preoperative surgery was done for precise and complete excision of the disease and to prevent injury to the left ureter and rectum. The surgery was performed as a two-step excision using a da Vinci Xi robot and included left ureterolysis, shaving of the bowel endometriosis nodule and full-thickness vaginal wall excision along with the infiltrating nodule. The infiltrating endometriosis nodule was split into two halves and was excised individually. Her postoperative VAS score for dysmenorrhea was 2/10, and she is 28 weeks pregnant at the time of submission. Advanced VR imaging can help in the evaluation and management of deep endometriosis. It can improve the surgeon's understanding of the specific anatomy, visualise the disease, and improve clinical outcomes.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"5513823"},"PeriodicalIF":0.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luísa Cerqueira, José Manuel Pereira, Marina Moucho
{"title":"Healthy Baby Delivery After 100 Days of Somatic Support in a Brain-Dead Pregnant Woman.","authors":"Luísa Cerqueira, José Manuel Pereira, Marina Moucho","doi":"10.1155/crog/2746188","DOIUrl":"10.1155/crog/2746188","url":null,"abstract":"<p><p>After diagnosing brain death, with few exceptions, it is unethical to maintain organ support. This decision may be considered in case of pregnancy to guarantee foetal viability and improve the perinatal outcome. We describe a case of prolonged organ support after brain death in a pregnant woman, following cardiac arrest secondary to an acute asthma attack. A 26-year-old primigravida, 18 weeks pregnant, with a history of stable asthma, was admitted to an ICU after cardiac arrest secondary to an acute asthma attack. It was possible to maintain organ support for 100 days with the collaboration of a multidisciplinary medical team. A healthy child was born, and favourable outcomes were observed at the 3-year follow-up. Brain death during pregnancy is a rare event and is a unique ethical, financial, and technical challenge. No guidelines are available for the management of these patients. This case demonstrates that it is possible to prolong organ support in this situation and successfully deliver a healthy child.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"2746188"},"PeriodicalIF":0.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12119159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emiko Hamada, Naomi Shiga, Mika Watanabe, Satoko Sato, Zen Watanabe, Masahito Tachibana, Masatoshi Saito
{"title":"A Rare Case of Uterine-Origin Vulvar Leiomyoma Occurring in a Juvenile Girl: Case Report and Literature Review.","authors":"Emiko Hamada, Naomi Shiga, Mika Watanabe, Satoko Sato, Zen Watanabe, Masahito Tachibana, Masatoshi Saito","doi":"10.1155/crog/8874924","DOIUrl":"https://doi.org/10.1155/crog/8874924","url":null,"abstract":"<p><p>Leiomyoma arising from the vulva is very rare, and it is difficult to differentiate it from a Bartholin gland cyst and aggressive angiomyxomas. We report a case of vulvar leiomyoma in a juvenile girl. The patient, a 16-year-old female, had noted a tender subcutaneous nodule on the right vulva for 2 years. At first, a Bartholin gland cyst was suspected, and she was prescribed antibiotics. However, because of persistent symptoms, the patient was referred to our clinic for further examination. An MRI scan suspected a mesenchymal tumor, and surgical resection was performed. Tumor cells were diffusely positive for anti-smooth muscle antibodies, HHF35, and Desmin, and leiomyoma was suspected. Immunostaining tests were negative for estrogen receptor and positive for progesterone receptor. The patient exhibited an excellent postoperative course with no evidence of recurrence at the latest follow-up. Surgical resection is the only curative treatment, and long-term follow-up is recommended because of rare reports of recurrence.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"8874924"},"PeriodicalIF":0.6,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minh Tam Le, Trung Van Nguyen, Hong Nhan Thi Dang, Quoc Huy Vu Nguyen
{"title":"Formation of Blastocysts From Zona Pellucida-Free Oocytes: A Case Report on a Modified Technique in In Vitro Fertilization.","authors":"Minh Tam Le, Trung Van Nguyen, Hong Nhan Thi Dang, Quoc Huy Vu Nguyen","doi":"10.1155/crog/5247242","DOIUrl":"https://doi.org/10.1155/crog/5247242","url":null,"abstract":"<p><p><b>Objective:</b> Zona-free oocytes (ZFOs) were rarely present when performing the intracytoplasmic sperm injection (ICSI) technique. There have been some reports showing that embryos from these oocytes still result in pregnancy after treatment. These oocytes are often discarded due to quality concerns and difficulties in manipulating and cultivating. This case report shows how ZFOs are handled in in vitro fertilization (IVF). <b>Methods:</b> This case report concerns IVF with ICSI and blastocyst culture in an infertile woman with polycystic ovary syndrome. A modified ICSI procedure was proposed to fertilize the ZFO without any damage. The primary outcome measurements involve fertilization assessment and blastocyst development. <b>Results:</b> Among 23 retrieved oocytes, 5 of them were zone ZFOs. Three of the five were fertilized and then developed into good-quality blastocysts. <b>Conclusions:</b> By employing appropriate techniques for fertilization and embryo culture, ZFOs are capable of the development and production of good-quality blastocysts.</p>","PeriodicalId":9610,"journal":{"name":"Case Reports in Obstetrics and Gynecology","volume":"2025 ","pages":"5247242"},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}