Serkan Civlan, Caghan Tonge, Emrah Keskin, Cagri Elbir, Goktug Ulku, Mehmet Selim Gel, Batuhan Bakirarar, Iskender Samet Daltaban, Mert Nazik, Ramazan Fesli, Eylem Teke, Nazar Ciltemek, Mustafa Arici, Nevzat Dogukan Erbek, Mehmet Erdal Coskun, Mehmet Erhan Turkoglu, Fatih Yakar
{"title":"The Initial Experience of Turkish Neurosurgical Stroke Centers: A National Study.","authors":"Serkan Civlan, Caghan Tonge, Emrah Keskin, Cagri Elbir, Goktug Ulku, Mehmet Selim Gel, Batuhan Bakirarar, Iskender Samet Daltaban, Mert Nazik, Ramazan Fesli, Eylem Teke, Nazar Ciltemek, Mustafa Arici, Nevzat Dogukan Erbek, Mehmet Erdal Coskun, Mehmet Erhan Turkoglu, Fatih Yakar","doi":"10.5137/1019-5149.JTN.48420-25.2","DOIUrl":"10.5137/1019-5149.JTN.48420-25.2","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the clinical and radiological outcomes of newly established Turkish neurosurgical stroke centers , and to assess their competency in managing acute ischemic stroke from June 2023 to June 2024.</p><p><strong>Material and methods: </strong>We retrospectively analyzed data from 69 patients (mean age = 69.06 ± 13.48 years) from three stroke centers in Türkiye by reviewing hospital records and patient interviews, focusing on demographic variables, comorbidities, treatment methodologies, outcomes (using the Modified Rankin Scale (mRS)), stroke severity (using the National Institutes of Health Stroke Scale [NIHSS]), Alberta Stroke Program Early CT (ASPECT) scores, reperfusion status (using the modified Thrombolysis in Cerebral Ischemia (mTICI) score), complications, blood glucose levels, and creatinine levels.</p><p><strong>Results: </strong>Of 392 acute ischemic stroke patients, 280 (71.4%) had no identifiable occlusion, 43 (11%) were out of the MT time window, and 69 (17.6%) underwent MT, with 57 (14.5%) having LVO and 12 (3%) MVO. Final reperfusion (mTICI ?2b) was achieved in 78.3% of MT patients, and 29% achieved favorable outcomes (mRS ?2) at three months. Younger age, lower baseline NIHSS, and higher ASPECT scores correlated with better outcomes, while elevated blood glucose ( > 127.50 mg/dL) and creatinine ( > 0.80 mg/dL) were linked to worse mRS scores. Complications occurred in 21.7%, including symptomatic intracranial hemorrhage in six patients.</p><p><strong>Conclusion: </strong>While Turkish neurosurgical stroke centers have made significant strides in managing acute ischemic stroke, challenges remain in optimizing patient outcomes. This initial experience underscores the need for further research, continued training, and educational standardization for neurosurgeons in endovascular techniques to improve patient care.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"537-545"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huseyin Biceroglu, Bilal Bahadir Akbulut, Okan Derin, Ozde Senol Akbulut, Mustafa Serdar Boluk, Nevhis Akinturk, Kadri Emre Caliskan, Cenk Eraslan, Servet Celik, Ahmet Acarer, Taskin Yurtseven
{"title":"Accuracy of Deep Brain Stimulation Lead Placement Using a Cranial Robotic Guidance Platform: A Preliminary Cadaveric Study.","authors":"Huseyin Biceroglu, Bilal Bahadir Akbulut, Okan Derin, Ozde Senol Akbulut, Mustafa Serdar Boluk, Nevhis Akinturk, Kadri Emre Caliskan, Cenk Eraslan, Servet Celik, Ahmet Acarer, Taskin Yurtseven","doi":"10.5137/1019-5149.JTN.47419-24.2","DOIUrl":"10.5137/1019-5149.JTN.47419-24.2","url":null,"abstract":"<p><strong>Aim: </strong>To measure the deviation rate of a custom 3D-printed Deep Brain Stimulation (DBS) lead holder assisted electrode placements from their intended targets, providing a benchmark for the system?s accuracy and paving the way for its use in standard DBS workflows.</p><p><strong>Material and methods: </strong>The study was conducted in an experimental lab using a cadaver obtained according to local regulations. Planned electrode trajectories, designed with Medtronic?s DBS surgery planning system, were transferred to the StealthStation Autoguide. A 3D-printed DBS lead holder with integrated navigation fiducials was used to place six electrodes in the targeted brain regions. Pre-operative CT and MRI scans were used for planning, and post-operative imaging confirmed electrode placement. Deviation from planned trajectories was analyzed using Python to assess accuracy.</p><p><strong>Results: </strong>Following a 30-minute registration and draping process, the median electrode placement time was 22.5 minutes (range: 15-120). The total surgical time for all six electrodes was approximately 5 hours, including imaging, adjustments, and confirmation. The median difference was 1.73 mm (0.03-5.45) on the X-axis, 1.86 mm (0.46-2.74) on the Y-axis, and 1.95 mm (0.73-4.4) on the Z-axis. The median vectorial difference was 2.68 mm (2.3-6.71), while the median trajectory difference was 3.01 mm (1.64-6.63).</p><p><strong>Conclusion: </strong>Despite 50% of leads having a vectorial difference exceeding 4 mm, most had a trajectory difference of less than 3 mm, which could be attributed to the inability to measure the length of the electrode precisely. These results suggest that with minor adjustments, the StealthStation Autoguide could be a cost-effective alternative to similar systems, though further cadaveric studies are necessary to address potential learning curves and random factors.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"580-586"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Ensemble Learning Approach for AI-based Classification of Paraganglioma/ Pheochromocytoma, Low Grade Glioma, and Glioblastoma Tumors.","authors":"Saliha Acar, Giyasettin Ozcan, Eyyup Gulbandilar","doi":"10.5137/1019-5149.JTN.46875-24.2","DOIUrl":"10.5137/1019-5149.JTN.46875-24.2","url":null,"abstract":"<p><strong>Aim: </strong>To propose a weighted vote-based ensemble classification method to classify paraganglioma/pheochromocytoma, low-grade glioma, and glioblastoma tumors-conditions that present with similar symptoms-against other central nervous system tumors using clinical and molecular data.</p><p><strong>Material and methods: </strong>This study utilized clinical and molecular data from The Cancer Genome Atlas database of the United States National Cancer Institute. Initially, categorical variables were transformed into numerical values, and class distribution imbalance was addressed through oversampling. The dataset was split, with 80% used for training across 10 different classical classification algorithms and the remaining 20% reserved for testing. A weighted vote-based ensemble classification algorithm was developed using six classifiers, artificial neural networks, logistic regression, extra trees, random forest, gradient boosting, and extreme gradient boosting, selected for their high classification accuracy. Additionally, feature importance analysis identified the most critical risk factors within the dataset.</p><p><strong>Results: </strong>The proposed algorithm achieved an accuracy of 90.4% and an area under the receiver operating characteristic curve of 0.968, indicating strong classification performance.</p><p><strong>Conclusion: </strong>The findings from this study suggest that the proposed method could be a valuable tool for supporting treatment planning in central nervous system tumor cases.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"627-635"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic or Microscopic Discectomy: Which One Do Neurosurgeons Prefer for Their Own Lumbar Disc Surgery?","authors":"Hakan Kina, Aydin Sinan Apaydin","doi":"10.5137/1019-5149.JTN.48513-25.3","DOIUrl":"10.5137/1019-5149.JTN.48513-25.3","url":null,"abstract":"<p><strong>Aim: </strong>To examine the factors influencing neurosurgeons? preferences between microscopic discectomy (MD) and endoscopic discectomy (ED) for the treatment of lumbar disc herniation (LDH) in Türkiye.</p><p><strong>Material and methods: </strong>A cross-sectional survey was administered to 229 active neurosurgeons in Türkiye. The 23-item questionnaire assessed various factors influencing the preference for ED or MD, including training, surgical experience, demographic characteristics, and institutional factors. Data analysis was performed via ANOVA, multivariate logistic regression, chi-square tests, t tests, and descriptive statistics. A thematic analysis was conducted on the open-ended responses.</p><p><strong>Results: </strong>The results revealed that while traditional MD remained the preferred technique among older and more experienced neurosurgeons, 62.9% of surgeons with endoscopic training favored ED. Surgical preferences are significantly influenced by handson experience and institutional support for endoscopic procedures. Although younger surgeons preferred ED, MD was favored in complex and emergency situations (p < 0.05).</p><p><strong>Conclusion: </strong>Younger surgeons increasingly opt for ED because of their familiarity with minimally invasive techniques, although MD remains the predominant approach among more experienced surgeons. Surgical decisions are heavily influenced by institutional support and practical experience. Continuous education and support for endoscopic methods will be essential for enhancing patient outcomes and integrating new technologies into clinical practice as surgical practices evolve.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"721-726"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral Thinning of the Temporal Bone: A Case Rep.","authors":"Ki Seong Eom","doi":"10.5137/1019-5149.JTN.47227-24.2","DOIUrl":"10.5137/1019-5149.JTN.47227-24.2","url":null,"abstract":"<p><p>Bone mass is maintained by a balance between bone formation by osteoblasts and resorption by osteoclasts. Calvarial thinning can occur because of various factors. However, no previous studies have described bilateral temporal thinning (BTT) of the skull. This report presents a case of a squamous part of the bilateral temporal bone in a patient with alcohol-induced liver cirrhosis. This is the first case of BTT exhibiting an appearance similar to that of bilateral parietal thinning (BPT) in a patient with osteoporosis caused by liver cirrhosis. Although the precise pathogenic mechanism underlying thinning of the squamous part of the temporal bone remains unclear, osteoporosis associated with diploë is presumed to have contributed to its development in this patient, and BTT is considered a variant of BPT.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"805-809"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidence and Factors of Tethering After Sectioning the Filum Terminale.","authors":"Duygu Baykal, Mevlut Ozgur Taskapilioglu","doi":"10.5137/1019-5149.JTN.48880-25.2","DOIUrl":"10.5137/1019-5149.JTN.48880-25.2","url":null,"abstract":"<p><strong>Aim: </strong>To assess the incidence of retethering in patients who underwent surgery for tethered cord in our clinic.</p><p><strong>Material and methods: </strong>We included patients who underwent surgical intervention for tethered cord in our clinic between 2010 and 2020, and were subsequently diagnosed with retethering during follow-up. Only those with available postoperative clinical follow-up data were included. The study analyzed the timing of surgery, gender, presenting symptoms, intraoperative findings, postoperative outcomes?including complications?and follow-up duration.</p><p><strong>Results: </strong>Over a 10-year period, 59 patients underwent surgery for tethered cord. Among them, 11 patients required reoperation for retethering at a median age of 5 years. The median interval between the initial and retethering surgeries was 47.6±43.20 months. Two patients were asymptomatic at the time of their initial surgery. Among the 11 patients with retethering, 3 (27.2%) presented with bladder or bowel dysfunction, 4 (36.3%) with neuro-orthopedic symptoms, and 4 (36.3%) with pain. Two patients experienced a second episode of retethering and required a third surgery, which occurred approximately 2 years after the second procedure.</p><p><strong>Conclusion: </strong>The risk of retethering should be carefully monitored in patients with tethered cord, particularly during growth periods.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"709-714"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serdar Kokar, Savas Sencan, Burak Yildiz, Berat Asim Polat, Rekib Sacaklidir, Osman Hakan Gunduz
{"title":"The Effect of Obesity on the Treatment Outcomes of Lumbar Transforaminal Epidural Steroid Injections.","authors":"Serdar Kokar, Savas Sencan, Burak Yildiz, Berat Asim Polat, Rekib Sacaklidir, Osman Hakan Gunduz","doi":"10.5137/1019-5149.JTN.45956-23.3","DOIUrl":"10.5137/1019-5149.JTN.45956-23.3","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effects of obesity on the treatment outcomes of lumbar transforaminal epidural steroid injections (TFESIs).</p><p><strong>Material and methods: </strong>This retrospective study included patients who underwent single-level TFESI in a pain management center between January 2021 and April 2023. Body mass index (BMI) of the patients was evaluated based on the World Health Organization guidelines. Non-obese individuals had a BMI below 25 kg/m2, those with a BMI between 25 and 30 kg/m2 were classified as overweight, and those with a BMI greater than or equal to 30 kg/m2 were deemed obese. The Numeric Rating Scale (NRS) scores for all patients before the procedure, at the first hour, and at the one-month follow-up were documented. Treatment success was defined as a 50% or more reduction in NRS score at one month of follow-up.</p><p><strong>Results: </strong>This study enrolled a total of 162 participants, with a mean age of 49.5 ± 13.7 years and an average BMI of 27.7 ± 4.36 kg/m2. The mean pre-procedural pain score was 8.3 (range, 4 to 10). Significant reductions were observed in the mean pain scores at the first hour (0.90) and first month (3.3), compared to the pre-procedural NRS scores (p < .001). Upon categorizing patients based on BMI, no significant differences were observed among the groups regarding age, gender, symptom duration, procedure level, magnetic resonance imaging (MRI) grade, pain scores, and treatment success.</p><p><strong>Conclusion: </strong>Since the potential effects of obesity on the short-term results of lumbar TFESI have not been elucidated yet, practitioners should continue to apply lumbar TFESI in patients with high BMI values.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"120-128"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dawud al-Antaki's Account on Macrocephaly and Microcephaly in al-Nuzhat al-Mubhija.","authors":"Ahmet Aciduman, Abdullah Yildiz","doi":"10.5137/1019-5149.JTN.47137-24.1","DOIUrl":"10.5137/1019-5149.JTN.47137-24.1","url":null,"abstract":"<p><strong>Aim: </strong>To present information regarding macrocephaly and microcephaly provided in D?w?d al-An??k??s Arabic book, al-Nuzhat al- Mubhija, which was translated into English and discussed in the context of the period?s literature.</p><p><strong>Material and methods: </strong>The copy of al-Nuzhat al-Mubhija, which was published in Egypt in 1324 AH/[1906/7 AD] (2nd edition) and another copy published in Beirut, Lebanon, in 1420 AH/1999 AD, were analyzed. The section on ?the change in the shape of the head? from the copy printed in Egypt was used as the reference and the copy printed in Lebanon was compared to it.</p><p><strong>Results: </strong>Al-An??k? presents that the change in head shape can be categorized into macrocephaly and microcephaly. Al-An??k? states that the head enlarges due to the separation of the cranial sutures, which occurs because of penetration of a humor between the sutures, accumulation of thick wind under the sutures, or trapping of fluids between the membranes. Al-An??k? recommends the use of solvents for the wind and fluids collected in the head, and surgical treatment (incision and evacuation) for cases in which fluids cannot be dissolved. However, he does not provide a detailed explanation about the surgical intervention. In this chapter, al- An??k? endeavors to provide an explanation of why microcephaly occurs, and organizes the treatment recommendations according to its proposed etiology.</p><p><strong>Conclusion: </strong>Al-An??k? briefly provides information regarding the etiology of macrocephaly and microcephaly and offers treatment suggestions for them. His treatment suggestions are in the context of and in line with the principles of humoral theory, which was the medical paradigm of the period. However, a recommendation for surgical intervention may be worth considering even in the absence of detailed information.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"202-207"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Serdar Oguzoglu, Halil Asci, Muhammet Yusuf Tepebasi, Ilter Ilhan, Nilgun Senol, Alpkaan Duran, Rumeysa Taner, Ozlem Ozmen
{"title":"Increased SIRT1 Signalling and VEGF Expressions by Dexpanthenol Suppress Oxidant, Inflammatory and Apoptotic Processes in a Rat Experimental Model of Subarachnoid Haemorrhage.","authors":"Ali Serdar Oguzoglu, Halil Asci, Muhammet Yusuf Tepebasi, Ilter Ilhan, Nilgun Senol, Alpkaan Duran, Rumeysa Taner, Ozlem Ozmen","doi":"10.5137/1019-5149.JTN.46741-24.3","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.46741-24.3","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effects of dexpanthenol (Dex) on subarachnoid haemorrhage (SAH) induced brain injury via sirtuin 1 (SIRT1) signaling in a rat experimental model.</p><p><strong>Material and methods: </strong>A total of 46 Wistar Albino rats were divided into 5 groups as control, sham, SAH, SAH+Dex, and Dex. First day; 0.3 ml of saline was given to the cisterna magna of the control, sham, and DEX group animals and 0.3 ml of autologous blood was given to SAH and SAH+Dex. On day 4; brain tissues of the rats were removed under anaesthesia. Brain tissues were collected for the biochemical analysis as total antioxidant level (TAS), total oxidant level (TOS), and oxidative stress index (OSI) levels; histopathological and immunohistochemical analysis as caspase-3 (Cas-3), vascular endothelial growth factor (VEGF); and genetical anaylsis as SIRT1/p53/B-cell lymphoma (BCL2)/Bcl-2-associated X protein (Bax).</p><p><strong>Results: </strong>Oxidant TOS, OSI levels, inflammatory TNF-?, apoptotic Cas-3, p53, Bax expressions enhanced and antioxidant TAS, antipoptotic BCL2, angiogenetic marker VEGF and SIRT1, which affects all these biomarkers decreased in the SAH group significantly. Besides significant subarachnoidal and parenchymal hemorrhage areas, edematous cerebral membranes, degenerative and necrotic changes and neuronophagies were observed. With the Dex treatment, a decrease was observed in the elevated oxidative, inflammatory, and apoptotic markers. Additionally, antioxidant, anti-apoptotic, VEGF, and SIRT1 levels, showed an increase.</p><p><strong>Conclusion: </strong>SAH caused inflammation, oxidative stress and apoptosis with decreasing levels of SIRT1 signaling and Dex treatment ameliorated and improved all these pathological conditions.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 3","pages":"454-462"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazenin Durmus, Mehmet Yigit Akgun, Tunc Oktenoglu, Mehdi Sasani, Ozkan Ates, Ali Fahir Ozer
{"title":"Dynamic Stabilization: A Game-Changer in Disc Herniation Surgery.","authors":"Nazenin Durmus, Mehmet Yigit Akgun, Tunc Oktenoglu, Mehdi Sasani, Ozkan Ates, Ali Fahir Ozer","doi":"10.5137/1019-5149.JTN.47287-24.3","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.47287-24.3","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the effectiveness of dynamic stabilization as an alternative to traditional fusion surgery for the treatment of lumbar disc herniation and degenerative disc disease, focusing on its impact on segmental stability and patient outcomes.</p><p><strong>Background: </strong>Back pain is a prevalent global health issue, often caused by abnormal load distribution rather than movement. Key diagnoses such as lumbar disc herniation and degenerative disc disease are linked to spinal instability. While classical surgical methods like discectomy and fusion have been standard, they often result in limited patient satisfaction and complications like adjacent segment degeneration. Lumbar Disc Herniation: Disc herniation involves the nucleus pulposus tearing the annulus fibrosus, causing pain through structural disruption or nerve root compression. Most cases resolve spontaneously, but a subset requires surgical intervention. Success of surgery depends on accurate assessment of segmental stability and patient-specific factors. Segmental Stability: Stability is crucial for preventing pain and neurological deficits. It depends on three subsystems: osteoligamentous, musculotendinous, and neural control. When one subsystem is compromised, instability occurs. Indicators for stabilization include insufficient muscle support, hypermobility, significant annular defects, and the presence of disc herniation with anterolisthesis or Modic changes. Dynamic Stabilization: Unlike rigid fusion, dynamic stabilization uses flexible materials to maintain physiological spinal movement and distribute loads. Initial systems aimed only for minor instability, but advancements now support movement preservation. Clinical outcomes show reduced adjacent segment stress and potential disc regeneration.</p><p><strong>Conclusion: </strong>Dynamic stabilization offers a promising alternative to fusion surgery by providing controlled stabilization and preserving spinal mobility. It addresses the limitations of fusion surgery, such as high complication rates and patient dissatisfaction, making it a significant advancement in the surgical treatment of lumbar disc herniation and degenerative disc disease.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 3","pages":"361-367"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}