Oral Oncology Reports最新文献_第4页

Corrigendum to “End of life and palliative care decisions in advanced head neck cancer” [Oral Oncol Rep 11 (2024) 100569] “晚期头颈癌的生命终结和姑息治疗决策”的勘误表[Oral Oncol Rep 11 (2024) 100569]

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-04-29 DOI: 10.1016/j.oor.2025.100744

Shrikant Balasaheb Mali

引用次数: 0

Corrigendum to “Nanotechnology in photodynamic therapy” [Oral Oncology Reports 10 (2024) 100307] “光动力治疗中的纳米技术”的勘误表[口腔肿瘤学报告10 (2024)100307]

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-05-10 DOI: 10.1016/j.oor.2025.100750

Shrikant B. Mali, Sachinkumar Dattatray Dahivelkar

引用次数: 0

Comprehensive nutritional index: A novel prognostic and quality of life tool in nasopharyngeal carcinoma care 综合营养指数：鼻咽癌护理中一种新的预后和生活质量工具

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-08-07 DOI: 10.1016/j.oor.2025.100763

Sharfunnisa S.H.

引用次数: 0

Prognostic significance of systemic inflammatory markers in oropharyngeal squamous cell carcinoma 口咽鳞状细胞癌全身炎症标志物的预后意义

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-06-18 DOI: 10.1016/j.oor.2025.100755

Jan Horackiewicz , Matthew Donachie , Nichola Philp , Marta Chmielecka , Mohd Afiq Mohd Slim , Rhona Hurley , Catriona M. Douglas

{"title":"Prognostic significance of systemic inflammatory markers in oropharyngeal squamous cell carcinoma","authors":"Jan Horackiewicz , Matthew Donachie , Nichola Philp , Marta Chmielecka , Mohd Afiq Mohd Slim , Rhona Hurley , Catriona M. Douglas","doi":"10.1016/j.oor.2025.100755","DOIUrl":"10.1016/j.oor.2025.100755","url":null,"abstract":"<div><h3>Introduction</h3><div>Incidence of oropharyngeal squamous cell carcinoma (OPSCC) is rising and is increasingly associated with human papillomavirus (HPV) infection, which makes up approximately 50 % of OPSCC cases in the UK. Patients presenting with HPV-positive OPSCC have better overall survival (OS) and prognosis. A significant proportion of these still have poor survival outcomes and identification of these patients remains a challenge. This study aims to investigate the predictive value of albumin, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), systemic immune inflammation index (SIII) for overall survival in OPSCC.</div></div><div><h3>Methods</h3><div>Seven hundred and twenty-eight patients were extracted from the West of Scotland Cancer Network database and met inclusion criteria with available blood markers at diagnosis. ROC curve analysis was constructed with respect to age, albumin and systemic inflammatory markers to determine diagnostic cut-offs, which were used to stratify subsequent Kaplan-Meier analyses. Univariate and multivariate analysis was carried out with respect to all baseline characteristics.</div></div><div><h3>Results</h3><div>Patients with lowered albumin, LMR and raised NLR, PLR and SIII presented with poorer OS over time as well as median survival times. HPV-negative patients presented with significantly poorer survival outcomes as compared to HPV-positive. Only albumin ≥35.5 g/L (HR = 0.683, 95 %CI 0.538–0.868) and NLR≥4.0 (HR = 1.416, 95 %CI 1.031–1.946) were found to be independent prognostic factors in patients with OPSCC.</div></div><div><h3>Conclusion</h3><div>Serum albumin and NLR represent valuable predictors of survival in OPSCC regardless of HPV status. A universal, diagnostic NLR cut-off remains unknown. Systemic inflammatory markers may be a helpful adjunct when assessing patients during MDT.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"15 ","pages":"Article 100755"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Narrow Band Imaging (NBI) as a non-invasive adjunct for margin assessment in oral squamous cell carcinoma (OSCC) 窄带成像（NBI）作为口腔鳞状细胞癌（OSCC）边缘评估的非侵入性辅助手段

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-08-14 DOI: 10.1016/j.oor.2025.100760

Krishnasamy Nitya , Yash Merchant , Somdipto Das , Sameep S. Shetty

{"title":"Use of Narrow Band Imaging (NBI) as a non-invasive adjunct for margin assessment in oral squamous cell carcinoma (OSCC)","authors":"Krishnasamy Nitya , Yash Merchant , Somdipto Das , Sameep S. Shetty","doi":"10.1016/j.oor.2025.100760","DOIUrl":"10.1016/j.oor.2025.100760","url":null,"abstract":"<div><div>The status of margins in OSCC is a critical prognostic factor that is known to influence local recurrence and overall survival outcomes. Positive or close surgical margins substantially increase the risk of locoregional failure, necessitating revision and adjuvant therapy that may adversely impact patients’ quality of life. Conventional intraoperative techniques of assessment of margins such as visual inspection, palpation, and selective frozen section analysis, have inherent limitations. These include subjectivity, sampling errors, and procedural delays. Narrow Band Imaging (NBI) is an innovative, non-contact, non-invasive optical imaging modality that enhances visualisation of the mucosal and submucosal microvasculature by employing filtered light at specific wavelengths. NBI enables more accurate delineation of tumour margins by accentuating vascular patterns associated with neoplastic transformation. This short correspondence discusses the fundamental principles, intraoperative applications, clinical advantages, and prospects of NBI as a valuable adjunct to conventional methods for margin assessment.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"15 ","pages":"Article 100760"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on prognostic significance of systemic inflammatory markers in oropharyngeal squamous cell carcinoma 口咽鳞状细胞癌全身炎症标志物预后意义的探讨

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-07-09 DOI: 10.1016/j.oor.2025.100756

Parth Aphale, Shashank Dokania, Himanshu Shekhar

引用次数: 0

Corrigendum to “Panoptosis – new frontier in research in head neck cancer” [Oral Oncol Rep 10 (2024) 100310] “Panoptosis -头颈癌研究的新前沿”的勘误表[Oral Oncol Rep 10 (2024) 100310]

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-05-10 DOI: 10.1016/j.oor.2025.100752

Shrikant Balasaheb Mali

引用次数: 0

Transforming malignant salivary gland tumor (MSGTs) treatment with AlphaFold: A promising approach AlphaFold转化恶性唾液腺肿瘤（MSGTs）治疗：一个有前途的方法

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-07-09 DOI: 10.1016/j.oor.2025.100757

Lucas Alves da Mota Santana , Rajiv Gandhi Gopalsamy , Juliana Batista Melo da Fonte , Bernardo Ferreira Brasileiro , Cleverson Luciano Trento , Matheus Leonel Paggi , Marina dos Santos Barreto , Charles dos Santos Estevam , Lysandro Pinto Borges

引用次数: 0

Corrigendum to “RNA-binding protein HuR reprograms immune T cells and promotes oral squamous cell carcinoma” [Oral Oncol Rep 10 (2024) 100296] “rna结合蛋白HuR重编程免疫T细胞并促进口腔鳞状细胞癌”的勘误表[oral Oncol Rep 10 (2024) 100296]

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-04-19 DOI: 10.1016/j.oor.2025.100740

Mrinmoyee Majumder , Harinarayanan Janakiraman , Paramita Chakraborty , Anitha Vijayakumar , Sari Mayhue , Hong Yu , Toros Dincman , Romeo Martin , Elizabeth O'Quinn , Shikhar Mehrotra , Viswanathan Palanisamy

引用次数: 0

Corrigendum to “Mini review of spatially fractionated radiation therapy for cancer management” [Oral Oncol Rep 9 (2024) 100175] “空间分割放射治疗用于癌症管理的综述”的勘误表[Oral Oncol Rep 9 (2024) 100175]

Oral Oncology Reports Pub Date : 2025-09-01 Epub Date: 2025-04-25 DOI: 10.1016/j.oor.2025.100741

Shrikant Balasaheb Mali

引用次数: 0