One health outlook最新文献

{"title":"Leptospirosis in India: insights on circulating serovars, research lacunae and proposed strategies to control through one health approach.","authors":"Baby Karpagam Krishnan, Ganesh Balasubramanian, Pesingi Pavan Kumar","doi":"10.1186/s42522-024-00098-5","DOIUrl":"10.1186/s42522-024-00098-5","url":null,"abstract":"<p><p>Leptospirosis is one of the most neglected zoonotic infections of public health concern worldwide and a remerging infection in tropical countries such as India. The infection least explored disease and the epidemiological and other critical data are scarce for the disease rate reported and to control the infection. Leptospirosis as sapronosis is as underrated as the infection itself, and this article aims to explore the significance of this aspect of the disease. The research review aimed at the epidemiological understanding of the infection to control the negative impact of the disease. A mixed review and analysis were carried out to understand the knowledge published on the critical and understudied areas like epidemiology, transmission, diagnosis, treatment, and control of infection. A systematic analysis was carried out to extract information about the reported circulating strains, and research lacunae in India with the published data available in PubMed. The article elaborately discusses crucial inference areas of infection transmission and addresses lacunae in critically unacclaimed areas of infection to control the spread of infection using one health approach (OHA), and strategies to control leptospiral infection are proposed. The article also reviewed how and why Leptospirosis can be best studied and controlled by \"One health approach\" in India.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11161969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141289095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A proposed One Health approach to control yellow fever outbreaks in Uganda.","authors":"Emmanuel Angmorteh Mensah, Samuel Ofori Gyasi, Fred Nsubuga, Walid Q Alali","doi":"10.1186/s42522-024-00103-x","DOIUrl":"10.1186/s42522-024-00103-x","url":null,"abstract":"<p><p>Yellow Fever (YF) is an acute viral hemorrhagic disease. Uganda is located within the Africa YF belt. Between 2019 and 2022, the Ugandan Health Authorities reported at least one outbreak of YF annually with an estimated 892 suspected cases, on average per year. The persistent recurrence of this disease raises significant concerns about the efficacy of current response strategies and prevention approaches. YF has been recognized as a One Health issue due to its interrelatedness with the animal and environmental domains. Monkeys have been recognized as the virus primary reservoir. The YF virus is transmitted through bites of infected Aedes or Haemagogus species mosquitoes between monkeys and humans. Human activities, monkey health, and environmental health issues (e.g., climate change and land use) impact YF incidence in Uganda. Additionally, disease control programs for other tropical diseases, such as mosquitoes control programs for malaria, impact YF incidence.This review adopts the One Health approach to highlight the limitations in the existing segmented YF control and prevention strategies in Uganda, including the limited health sector surveillance, the geographically localized outbreak response efforts, the lack of a comprehensive vaccination program, the limited collaboration and communication among relevant national and international agencies, and the inadequate vector control practices. Through a One Health approach, we propose establishing a YF elimination taskforce. This taskforce would oversee coordination of YF elimination initiatives, including implementing a comprehensive surveillance system, conducting mass YF vaccination campaigns, integrating mosquito management strategies, and enhancing risk communication. It is anticipated that adopting the One Health approach will reduce the risk of YF incidence and outbreaks.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"9"},"PeriodicalIF":3.8,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11119388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141088483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection and antibiogram profile of diarrheagenic Escherichia coli isolated from two abattoir settings in northwest Ethiopia: a one health perspective.","authors":"Solomon Lulie Abey, Mersha Teka, Abebe Belete Bitew, Wassie Molla, Mebrat Ejo, Gashaw Getaneh Dagnaw, Takele Adugna, Seleshe Nigatu, Bemrew Admassu Mengistu, Mebrie Zemene Kinde, Adugna Berju, Mequanint Addisu Belete, Wudu Temesgen, Shimelis Dagnachew, Tesfaye Sisay Tesema","doi":"10.1186/s42522-024-00102-y","DOIUrl":"10.1186/s42522-024-00102-y","url":null,"abstract":"<p><strong>Background: </strong>Diarrheagenic Escherichia coli (E. coli) is a zoonotic pathogen that contaminates abattoir workers, slaughter environments, slaughter equipment, and carcasses during abattoir processing. Infection with E. coli is associated with the consumption of contaminated food and water, and it is a potential threat to the health and welfare of both humans and animals. Hence, this study aimed to detect diarrheagenic E. coli and assess its antibiogram profile in two abattoir settings, in one health lens.</p><p><strong>Methods: </strong>A cross-sectional study in one health approach was conducted from December 2020 to June 2021. A total of 384 samples from abattoir workers' hands, carcasses, knives, cattle feces, abattoir water and effluents were collected. Bacterial culture and biochemical tests were conducted to isolate E. coli, while conventional polymerase chain reaction was performed to identify virulence genes. The antibiogram of diarrheagenic E. coli was tested against nine antimicrobials using the Kirby Bauer disk diffusion method.</p><p><strong>Results: </strong>A total of 115 (29.95%) E. coli were isolated from the 384 samples, and from these isolates, about 17 (14.8%) were confirmed to be diarrheagenic E. coli (DEC). Among the DEC pathotypes, nine (52.94%), five (29.4%), and three (17.65%) were Shiga toxin-producing, enterohemorrhagic, and enterotoxigenic E. coli, respectively. While 14 (82.35%) DEC isolates harbored the stx2 gene, five (29.41%) the eae gene, five (29.41%) the hlyA gene and three (17.65%) harbored the st gene. All the DEC isolates were resistant to erythromycin and vancomycin; whereas, they were susceptible to ampicillin, nalidixic acid and norfloxacin. Furthermore, 64.7% of DEC isolates showed resistance to both ceftazidime and kanamycin and 88.24% of the isolates showed multidrug resistance.</p><p><strong>Conclusion: </strong>This study detected DEC isolates having different virulence genes, which showed single and multiple antimicrobial resistance. Given the existing poor hygienic and sanitary practices along the abattoir-to-table food chain, coupled with the habit of raw meat consumption, this result indicates a potential public and animal health risk from the pathogen and antimicrobial resistance.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11071326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific highlights of the 9th ESWI Influenza Conference.","authors":"Leslie Reperant, Colin A Russell, Albert Osterhaus","doi":"10.1186/s42522-024-00099-4","DOIUrl":"10.1186/s42522-024-00099-4","url":null,"abstract":"<p><p>The European Scientific Working Group on Influenza (ESWI) held the 9th ESWI Influenza Conference in Valencia from 17-20 September 2023. Here we provide a summary of twelve key presentations, covering major topics on influenza virus, respiratory syncytial virus (RSV) and SARS coronavirus 2 (SARS-CoV-2) including: infection processes beyond acute respiratory disease, long COVID, vaccines against influenza and RSV, the implications of the potential extinction of influenza B virus Yamagata lineage, and the threats posed by zoonotic highly pathogenic avian influenza viruses.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10986029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140338506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time series of chicken stool metagenomics and egg metabolomics in changing production systems: preliminary insights from a proof-of-concept.","authors":"Michael E G Rosch, Jacqueline Rehner, Georges P Schmartz, Sascha K Manier, Uta Becker, Rolf Müller, Markus R Meyer, Andreas Keller, Sören L Becker, Verena Keller","doi":"10.1186/s42522-024-00100-0","DOIUrl":"10.1186/s42522-024-00100-0","url":null,"abstract":"<p><strong>Background: </strong>Different production systems of livestock animals influence various factors, including the gut microbiota.</p><p><strong>Methods: </strong>We investigated whether changing the conditions from barns to free-range chicken farming impacts the microbiome over the course of three weeks. We compared the stool microbiota of chicken from industrial barns after introducing them either in community or separately to a free-range environment.</p><p><strong>Results: </strong>Over the six time points, 12 taxa-mostly lactobacilli-changed significantly. As expected, the former barn chicken cohort carries more resistances to common antibiotics. These, however, remained positive over the observed period. At the end of the study, we collected eggs and compared metabolomic profiles of the egg white and yolk to profiles of eggs from commercial suppliers. Here, we observed significant differences between commercial and fresh collected eggs as well as differences between the former barn chicken and free-range chicken.</p><p><strong>Conclusion: </strong>Our data indicate that the gut microbiota can undergo alterations over time in response to changes in production systems. These changes subsequently exert an influence on the metabolites found in the eggs. The preliminary results of our proof-of-concept study motivate larger scale observations with more individual chicken and longer observation periods.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10979557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140320316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: The One Health High-Level Expert Panel (OHHLEP).","authors":"Thomas C Mettenleiter, Wanda Markotter, Dominique F Charron, Wiku B Adisasmito, Salama Almuhairi, Casey Barton Behravesh, Pépé Bilivogui, Salome A Bukachi, Natalia Casas, Natalia Cediel Becerra, Abhishek Chaudhary, Janice R Ciacci Zanella, Andrew A Cunningham, Osman Dar, Nitish Debnath, Baptiste Dungu, Elmoubasher Farag, George F Gao, David T S Hayman, Margaret Khaitsa, Marion P G Koopmans, Catherine Machalaba, John S Mackenzie, Serge Morand, Vyacheslav Smolenskiy, Lei Zhou","doi":"10.1186/s42522-024-00096-7","DOIUrl":"10.1186/s42522-024-00096-7","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"6"},"PeriodicalIF":3.8,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing One Health capacities for transboundary zoonotic diseases at the Libya-Tunisia border.","authors":"Lauren N Miller, Walid K Saadawi, Wafa Ben Hamouda, Ahmed S Elgari, Emaduldin A Abdulkarim, Ashur M M Lmrabet, Abir E Elbukhmari, Kaouther Harabech, Ammar Ali Jemai, Milad Farhat, Rasha Al-Azab, Abdulaziz Zorgani, Omar Elamher, Tarek Al Sanouri, Claire J Standley, Erin M Sorrell","doi":"10.1186/s42522-024-00101-z","DOIUrl":"10.1186/s42522-024-00101-z","url":null,"abstract":"<p><strong>Background: </strong>The dynamic nature of zoonotic emergence, spillover and spread necessitates multisectoral coordination beyond national borders to encompass cross-boundary and regional cooperation. Designated points of entry (POEs), specifically ground crossings, serve as critical locales for establishing and maintaining robust prevention, detection, notification, coordination, and response mechanisms to transboundary emerging and re-emerging disease threats. In order to better assess One Health capacities for transboundary zoonotic diseases (TZD) prevention, detection and response we adapted an existing tool, One Health Systems Assessment for Priority Zoonoses (OHSAPZ), for a cross-border, POE setting in North Africa.</p><p><strong>Methods: </strong>The One Health Transboundary Assessment for Priority Zoonoses (OHTAPZ) tool was used to support prioritization of transboundary zoonoses and analyze operational capacities between national and subnational-level human and animal health stakeholders from Libya and Tunisia. Country partners jointly identified and prioritized five TZDs of concern. Case study scenarios for each priority pathogen were used to elicit current disease operations, as well as multisectoral and bilateral engagement networks. Finally, a gap analysis was performed to determine bilateral strengths and weaknesses to TZDs.</p><p><strong>Results: </strong>The five priority TZDs jointly confirmed to undergo One Health assessment were avian influenza (low and high pathogenic strains); brucellosis; Rift Valley fever; Crimean-Congo hemorrhagic fever; and rabies. Using the qualitative information collected, a transboundary systems map schematic was developed outlining the movement of human patients, animals, diagnostic samples, and routes of communication and coordination both within and between countries for zoonotic diseases.</p><p><strong>Conclusions: </strong>Analysis of current operations (prevention, detection, surveillance, laboratory capacity, quarantine/isolation, and response) and the resulting transboundary systems map schematic helped identify existing capacity strengths for certain priority pathogens, as well as challenges to timely information-sharing and coordination. We developed targeted recommendations to address these limitations for joint action planning between Libya and Tunisia.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10953064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Members' experiences and perceptions of participating in an Australian Regional One Health Network.","authors":"Kirrilly Thompson, Joanne Taylor, Peter D Massey, David N Durrheim","doi":"10.1186/s42522-023-00093-2","DOIUrl":"10.1186/s42522-023-00093-2","url":null,"abstract":"<p><strong>Background: </strong>The One Health framework is intended to optimise the interdependent health of humans, animals and ecosystems. It relies on effective collaborations across disciplines, sectors and communities. One Health networks have become increasingly important platforms for encouraging, creating and supporting collaborations. Their success is usually judged by evaluations of their outputs. However, there is also a need to understand member experiences and perceptions of the networks in which they participate. To that end, we undertook the first membership survey of a One Health network that was established in Australia in 2005.</p><p><strong>Methods: </strong>An online membership survey was created, comprising closed and open-ended questions.</p><p><strong>Results: </strong>Around one third of the Regional One Health Partnership ('the Network') participated in the study (33 members). Participants contributed a combined total of 170 years of experience in the Network and 414 years of combined experience working in/on One Health. The Network has provided excellent opportunities for cross sectoral collaboration that would otherwise not have been possible. Findings also highlighted the intangible benefits of membership such as the creation of a collaborative support group for emerging and established One Health practitioners.</p><p><strong>Conclusions: </strong>The Network plays an important role in One Health collaborations in New South Wales and further afield. Commensurate with the literature on One Health collaborations globally, we identified a need for greater diversity amongst members, especially from First Nations people, local communities, non-government organisations and wildlife/environment experts, as well as concerted attempts to identify policy implications. Our membership survey tool could be adapted for future One Health Network membership surveys in Australia and internationally.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10782705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139428228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Rift valley fever outbreak in Sembabule District, Uganda, December 2020.","authors":"Freda Loy Aceng, Joshua Kayiwa, Peter Elyanu, Joseph Ojwang, Luke Nyakarahuka, Stephen Balinandi, Jayne Byakika-Tusiime, Alfred Wejuli, Julie Rebecca Harris, John Opolot","doi":"10.1186/s42522-023-00095-0","DOIUrl":"10.1186/s42522-023-00095-0","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"6 1","pages":"1"},"PeriodicalIF":3.8,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10763349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution and ecology of Jeilongvirus among wild rodents and shrews in Singapore.","authors":"Lena Ch'ng, Dolyce H W Low, Sophie A Borthwick, Rong Zhang, Zoe A Ong, Yvonne C F Su, Alan T Hitch, Gavin J D Smith, Ian H Mendenhall","doi":"10.1186/s42522-023-00094-1","DOIUrl":"https://doi.org/10.1186/s42522-023-00094-1","url":null,"abstract":"<p><strong>Background: </strong>Jeilongvirus was proposed as a new genus within the Paramyxoviridae in 2018. The advancement in metagenomic approaches has encouraged multiple reports of Jeilongvirus detection following the initial species discovery, enriching species diversity and host range within the genus. However, Jeilongvirus remains understudied in Singapore, where interfaces between humans and small mammals are plentiful.</p><p><strong>Methods: </strong>Here, we utilized metagenomic sequencing for the exploration of viral diversity in small mammal tissues. Upon discovery of Jeilongvirus, molecular screening and full genome sequencing was conducted, with the data used to conduct statistical modelling and phylogenetic analysis.</p><p><strong>Results: </strong>We report the presence of Jeilongvirus in four species of Singapore wild small mammals, detected in their spleen and kidney. We show that full genomes of three Singapore Jeilongvirus encode for eight ORFs including the small hydrophobic and transmembrane proteins. All generated genomes cluster phylogenetically within the small mammal subclade, but share low genetic similarity with representative Jeilongvirus species. Statistical modelling showed no spatial or temporal patterns and differences among species, life history traits and habitat types.</p><p><strong>Conclusions: </strong>This study serves as a basis for understanding dynamics between Jeilongvirus and small mammal hosts in Singapore by displaying the virus generalist nature. In addition, the initial detection can help to invoke improved routine surveillance and detection of circulating pathogens in synanthropic hosts.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"5 1","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10726567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138815926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}