One health outlook最新文献

{"title":"One Health, many voices: advances and challenges in toxoplasmosis discussed at the VII Brazilian symposium and IV international symposium on toxoplasmosis.","authors":"Rafael M Mariante, Lilian M G Bahia-Oliveira, Rosalynd V R Moreira, Ana L Q C Aleixo, Juliana Q Reimão, Andressa F da Silva, Ericka V M Carellos, Fernanda F Evangelista, Maria R R Amendoeira, Cristina G Carvalheiro, Renato A DaMatta","doi":"10.1186/s42522-026-00216-5","DOIUrl":"https://doi.org/10.1186/s42522-026-00216-5","url":null,"abstract":"<p><p>The VII Brazilian Symposium on Toxoplasmosis (SIMBRATOX) and the IV International Symposium on Toxoplasmosis (SINTOX) were held remotely from October 6 to 8, 2025, under the theme \"Toxoplasmosis - Strengthening the Connection between Science and Society for Global Health.\" The meeting brought together researchers, health professionals, policymakers, and representatives of civil society from Brazil and abroad, fostering interdisciplinary dialogue grounded in One Health and Global Health perspectives. Scientific sessions and roundtables addressed key dimensions of toxoplasmosis, including human, animal, and environmental transmission pathways; advances in therapeutics and vaccine research; veterinary and epidemiological surveillance; and health education strategies for prevention. Clinical discussions focused on congenital, ocular, and immunocompromised-associated toxoplasmosis, while other sessions examined food- and waterborne transmission, environmental contamination, and emerging challenges linked to parasite diversity. Social and legal panels highlighted patient advocacy, equity, and access to public policies as integral components of disease control. This commentary summarizes the main themes, debates, and perspectives that emerged during the three-day meeting, positioning toxoplasmosis as a model for operationalizing One Health approaches in complex infectious diseases.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"8 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low detection of Trypanosoma cruzi in invasive Rattus spp. across rural and natural habitats in central Chile.","authors":"Daniela Elizondo, Rodrigo Salgado, Cristian Herrera, Gabriela Gaona, Gemma Rojo, Nélida R Villaseñor, Ananda Müller, Francisco Chacón, André V Rubio","doi":"10.1186/s42522-026-00214-7","DOIUrl":"https://doi.org/10.1186/s42522-026-00214-7","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147719128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovating for One Health: federal perspectives and key lessons on building integrative programs for wildlife in Canada.","authors":"Alana A E Wilcox, Craig Stephen, Jennifer F Provencher","doi":"10.1186/s42522-026-00207-6","DOIUrl":"https://doi.org/10.1186/s42522-026-00207-6","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological characteristics of brucellosis in non-occupational population in Zhejiang Province, China, 2018-2024: epidemic trend and infection analysis.","authors":"Xuguang Shi, Yong Yang, Ying Liu, Jiangping Ren, Rong Zhang, Song Guo, Huimin Ma, Jimin Sun","doi":"10.1186/s42522-026-00212-9","DOIUrl":"https://doi.org/10.1186/s42522-026-00212-9","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"8 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence of Q fever among humans and animals in East Africa: a systematic review and meta-analysis.","authors":"Simegnew Adugna Kallu, Ambachew Motbaynor Wubaye, Simachew Getaneh Endalamew, Andnet Yirga Assefa, Alebachew Tilahun Wassie, Migbaru Keffale Bezabih, Yihenew Getahun Ambaw","doi":"10.1186/s42522-026-00209-4","DOIUrl":"https://doi.org/10.1186/s42522-026-00209-4","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147617338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for anthrax in livestock: findings from one health outbreak investigations in Bangladesh.","authors":"Muhammad Belal Hossain, Najmul Haider, Md Saiful Islam, Sukanta Chowdhury, Ahmad Raihan Sharif, M Salim Uzzaman, Mohammad Mostafizur Rahman, Mahbubur Rahman, Mahmudur Rahman, Farhana Haque","doi":"10.1186/s42522-026-00210-x","DOIUrl":"https://doi.org/10.1186/s42522-026-00210-x","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147583545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and antimicrobial resistance patterns of Campylobacter jejuni isolated from beef and bovine milk in Gondar town, Amhara region, Ethiopia.","authors":"Seleshe Nigatu, B Dejene, B Adugna, H Belete, Sadam M Ibrahim, Ahmed G Abdelhamid, Ahmed E Yousef, A B Gashaw, M Araya","doi":"10.1186/s42522-026-00208-5","DOIUrl":"10.1186/s42522-026-00208-5","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chamomile oil and apigenin as novel modulators of mexA, mexB, mexR, and oprM efflux pump genes in multidrug-resistant Pseudomonas aeruginosa.","authors":"Hozan Salahadin Mahdi, Salah Tofik Jalal Balaky","doi":"10.1186/s42522-026-00204-9","DOIUrl":"10.1186/s42522-026-00204-9","url":null,"abstract":"<p><strong>Background: </strong>Recent studies have shown that antimicrobial resistance has become a great threat. This study focuses on and investigates the effect of some natural compounds on the expression of efflux pump genes that play an important role in antimicrobial resistance in Pseudomonas aeruginosa.</p><p><strong>Methods: </strong>Among the 93 Pseudomonas aeruginosa that were isolated from different clinical samples, 20% were multidrug-resistant, 32% were extensively drug-resistant, and 2% were pandrug-resistant. Identification of the isolates was done using 16S rRNA gene amplification and sequencing. GC-MS analysis of chamomile oil revealed (is-.beta.-Farnesene) as the major component. Minimum inhibitory concentration values of each of apigenin, chamomile oil, and ceftazidime were evaluated for five of the isolates. Bacterial growth curve analysis revealed a decline in bacterial growth after treatment with sub-MIC levels of chamomile oil and apigenin. The gene expression of each mexA, mexB, mexR, and oprM efflux pump gene in the bacterial isolates using quantitative PCR was evaluated in untreated and treated isolates with a sub-MIC value of apigenin and chamomile oil.</p><p><strong>Results: </strong>Chamomile oil significantly reduced the expression of all four genes. On the other hand, apigenin downregulated most genes but upregulated mexA in two isolates and mexB in one isolate. Meanwhile, Chamomile oil exhibited stronger downregulation of efflux pump genes compared to apigenin, with fold changes ranging from 2.28 to 14.3.</p><p><strong>Conclusions: </strong>Accordingly, these novel findings suggest that chamomile oil and apigenin can have a significant effect on inhibiting efflux pump gene expression, thus combating multidrug-resistant P. aeruginosa, and offering new avenues for developing effective natural therapeutic adjuvants to overcome antibiotic resistance. This is preliminary evidence for the gene regulatory potential of chamomile oil and apigenin.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13134216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two decades (2005 to 2025) of avian influenza research trends, knowledge gaps and distribution of emerging H5N1 2.3.4.4b clade in South Asia.","authors":"Md Zulfekar Ali, Uwem Okon Edet, Md Salauddin, Clement Meseko","doi":"10.1186/s42522-026-00206-7","DOIUrl":"10.1186/s42522-026-00206-7","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13037272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147489272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental degradation as a recipe for emerging viral diseases: implications for global health.","authors":"Shuaibu Abdullahi Hudu, Abdulgafar Olayiwola Jimoh, Syafinaz Amin-Nordin, Sharifah Syed Hassan","doi":"10.1186/s42522-026-00203-w","DOIUrl":"10.1186/s42522-026-00203-w","url":null,"abstract":"","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13003655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147483033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}