One health outlook最新文献

{"title":"New area of occurrence of human brucellosis in Brazil: serological and molecular prevalence and risk factors associated with Brucella abortus infection.","authors":"Thaís de Souza de Matos, Ana Leticia Pereira Fernandes, Ividy Bison, Andréa Silva de Medeiros Bandeira, Wigínio Gabriel de Lira Bandeira, Jordan de Castro Nunes, Eduardo Sérgio Soares Souza, Vinícius Pietta Perez, Vinicius Longo Ribeiro Vilela, Roberta Nunes Parentoni, Arthur Willian de Lima Brasil","doi":"10.1186/s42522-024-00131-7","DOIUrl":"10.1186/s42522-024-00131-7","url":null,"abstract":"<p><strong>Background: </strong>Brucellosis is a re-emerging underdiagnosed zoonosis that has significant relevance, especially in developing countries. This study aimed to report the first cases of human brucellosis in the state of Paraíba, Brazil, and to determine the prevalence and risk factors associated with Brucella abortus infection in slaughterhouse workers.</p><p><strong>Methods: </strong>A cross-sectional study was carried out from December 2021 to February 2022 in public and private slaughterhouses in the state of Paraíba. Blood samples were collected from 188 people and tested using the Rose Bengal Test (RBT), a screening test, and the 2-mercaptoethanol (2-ME) and standard tube agglutination test (STAT), which are confirmatory tests. Samples that tested positive were subjected to molecular analysis using qPCR. Risk factors were determined through multivariate analysis based on epidemiological questionnaires administered to the workers. After the diagnoses, results were provided to the participants, and health education campaigns were conducted for all workers in the evaluated slaughterhouses.</p><p><strong>Results: </strong>The study found a serological prevalence (RBT + 2-ME + STAT) of 4.2% (16/188) (95% CI = [1.28; 6.96], sensibility 90% specificity 95%)among workers. Five samples were positive in qPCR with Ct (Cycle threshold ) values ranging from 31.58 to 38.11. The ingestion of undercooked meat was identified as a risk factor, with a 2.95 times higher chance of contamination. Among the 16 individuals who tested positive in the serological tests, 15 (p<0.0001) reported in the epidemiological questionnaire that they did not know what brucellosis is.</p><p><strong>Conclusion: </strong>These are the first published cases of human brucellosis in the state of Paraíba, reinforcing the hypothesis that the bacterium is circulating among slaughterhouse workers. This underscores the need to develop public policies that provide adequate medical support to the population.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"8"},"PeriodicalIF":3.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of climatic changes in the emergence and re-emergence of infectious diseases: bibliometric analysis and literature-supported studies on zoonoses.","authors":"Walter Leal Filho, Gustavo J Nagy, Gouvidé Jean Gbaguidi, Shlomit Paz, Maria Alzira Pimenta Dinis, Johannes M Luetz, Ayyoob Sharifi","doi":"10.1186/s42522-024-00127-3","DOIUrl":"10.1186/s42522-024-00127-3","url":null,"abstract":"<p><p>Climate change (CC) is increasingly recognised as a critical driver in the emergence and re-emergence of infectious diseases. The relationship between CC and infectious diseases is complex and multifaceted, encompassing changes in temperature, precipitation patterns, and extreme weather events. This study describes the role of CC in the emergence and re-emergence of infectious diseases, emphasising zoonoses. It used a mixed methodology, including an initial literature contextualisation and a bibliometric analysis, to identify key thematic research areas related to CC and zoonotic diseases and show their connections. The research relied on the Scopus database for the identification of relevant source literature and focused the search query on publications in English. VOSviewer was used to discover clear thematic clusters that illustrate what research areas have been addressed in the literature and how they are interlinked. In addition, the research selected and analysed twelve literature-supported studies to investigate the relevance of the zoonoses involved in infectious disease emergence and re-emergence linked to CC impacts. Many pathogens and their vectors, such as mosquitoes, ticks, and rodents, are sensitive to temperature and moisture. CC can expand or shift the geographical distribution of these vectors, bringing diseases to new areas. Warmer temperatures may allow mosquitoes that transmit diseases like malaria and dengue fever to survive and reproduce in regions that were previously too cold. Also, extreme events such as floods, droughts, and hurricanes can lead to immediate increases in waterborne and vector-borne diseases (VBD) by facilitating the spread of pathogens. There is a need to better understand the connections between CC and zoonoses. To address the challenges posed by zoonoses linked to CC, international organizations like the WHO should coordinate a global response to provide clear guidance. Governments must integrate CC and zoonoses into national health policies, ensuring that health frameworks address these interconnected risks. Funding should be allocated for research on the root causes of CC and for strengthening defenses, particularly in developing countries with fragile health systems. Additionally, enhanced communication, education, and training for healthcare professionals about the links between CC and zoonoses are essential for raising awareness and promoting proactive measures.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"12"},"PeriodicalIF":3.8,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing a one health data integration framework focused on real-time pathogen surveillance and applied genomic epidemiology.","authors":"Hanna N Oltean, Beth Lipton, Allison Black, Kevin Snekvik, Katie Haman, Minden Buswell, Anna E Baines, Peter M Rabinowitz, Shannon L Russell, Sean Shadomy, Ria R Ghai, Steven Rekant, Scott Lindquist, Janet G Baseman","doi":"10.1186/s42522-024-00133-5","DOIUrl":"10.1186/s42522-024-00133-5","url":null,"abstract":"<p><strong>Background: </strong>The One Health approach aims to balance and optimize the health of humans, animals, and ecosystems, recognizing that shared health outcomes are interdependent. A One Health approach to disease surveillance, control, and prevention requires infrastructure for coordinating, collecting, integrating, and analyzing data across sectors, incorporating human, animal, and environmental surveillance data, as well as pathogen genomic data. However, unlike data interoperability problems faced within a single organization or sector, data coordination and integration across One Health sectors requires engagement among partners to develop shared goals and capacity at the response level. Successful examples are rare; as such, we sought to develop a framework for local One Health practitioners to utilize in support of such efforts.</p><p><strong>Methods: </strong>We conducted a systematic scientific and gray literature review to inform development of a One Health data integration framework. We discussed a draft framework with 17 One Health and informatics experts during semi-structured interviews. Approaches to genomic data integration were identified.</p><p><strong>Results: </strong>In total, 57 records were included in the final study, representing 13 pre-defined frameworks for health systems, One Health, or data integration. These frameworks, included articles, and expert feedback were incorporated into a novel framework for One Health data integration. Two scenarios for genomic data integration were identified in the literature and outlined.</p><p><strong>Conclusions: </strong>Frameworks currently exist for One Health data integration and separately for general informatics processes; however, their integration and application to real-time disease surveillance raises unique considerations. The framework developed herein considers common challenges of limited resource settings, including lack of informatics support during planning, and the need to move beyond scoping and planning to system development, production, and joint analyses. Several important considerations separate this One Health framework from more generalized informatics frameworks; these include complex partner identification, requirements for engagement and co-development of system scope, complex data governance, and a requirement for joint data analysis, reporting, and interpretation across sectors for success. This framework will support operationalization of data integration at the response level, providing early warning for impending One Health events, promoting identification of novel hypotheses and insights, and allowing for integrated One Health solutions.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"9"},"PeriodicalIF":3.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human-bat contacts in the Netherlands, and potential risks for virus exchange.","authors":"L Begeman, M J M Geschiere, W F de Boer, J M A van den Brand, P L Eblé, J H T C van der Kerkhof, I Keur, P H C Lina, C B E M Reusken, M de Rosa, M J Schillemans, I Schreuder, C M Swaan, K van Zoonen, T Kuiken","doi":"10.1186/s42522-024-00132-6","DOIUrl":"10.1186/s42522-024-00132-6","url":null,"abstract":"<p><strong>Background: </strong>Contacts between people and free-ranging animals have a potential to cause viral disease epidemics when novel viruses are exchanged. The Netherlands has approximately 18 native bat species, of which some generally use buildings for roosting, and has a dense human population. Frequent indirect and direct contacts between bats and humans could thus be expected, however, this has hardly been studied.</p><p><strong>Methods: </strong>To study human-bat contacts, people living in the Netherlands were questioned about the type and frequency of their bat contacts, their bat knowledge and perception of bats. For analyses respondents were grouped into (1) general population, (2) bat contact risk group, and (3) people that live in a house with a roost site for a Common Pipistrelle Bat maternity group. Associations between human-bat contacts and other variables were tested by an ordinal logistic regression model.</p><p><strong>Results: </strong>We show that 85% (226/265) of group 1 reported no contacts, while 11% (28/265) reported indirect, and 4% (11/265) direct contacts with live bats, dead bats or bat products as their closest type of contacts. These contacts occurred mostly less than yearly. Somewhat similarly, the majority, 69% (9/13) of group 3 reported no contacts, and 15% (2/13) reported indirect contacts and 15% (2/13) reported direct contacts. These occurred monthly to less than yearly. In contrast, a minority, 5% (11/227) in group 2 reported no contacts, while 37% (85/227) reported direct bat contacts, mostly yearly, and 38% (86/227) reported bat-related injury, mostly less than yearly, as their closest type of contact. Overall, an increase in knowledge on bats and bat-related diseases was correlated with closer bat contacts.</p><p><strong>Conclusions: </strong>We conclude that even though bats live close to people in the Netherlands, direct contacts between bats, or bat products, and humans are rare in people from the general population, while being common in people involved in bat-related work. Mitigation of human-bat contacts will be most efficient when targeted to specific groups that are likely to have contacts with bats.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"7"},"PeriodicalIF":3.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11829522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Documenting challenges in achieving rabies elimination by 2030 in low-middle income countries; a Kenyan case study from Lamu County, 2020-2022: mixed methods approach.","authors":"Nassoro Mwanyalu, Athman Mwatondo, Veronicah Chuchu, Kimani Maina, Mathew Muturi, Mathew Mutiiria, Daniel Chepkwony, Maurice Owiny, Peninah Munyua","doi":"10.1186/s42522-024-00129-1","DOIUrl":"10.1186/s42522-024-00129-1","url":null,"abstract":"<p><strong>Background: </strong>Kenya launched a Rabies Elimination Strategy in 2014, aiming to end human rabies deaths by 2030. In March 2022, Lamu County reported increased cases of human dog bites and suspected rabies deaths to the Ministry of Health (MoH). We aimed to establish the extent of the rabies outbreak in humans and animals and determine the challenges to achieving rabies elimination by 2030.</p><p><strong>Methods: </strong>We extracted dog bite reports from the Kenya Health Information System (KHIS), national surveillance database system, and reviewed medical records at health facilities in Lamu County for suspected human rabies deaths from 2020 to 2022. We obtained information about animal bites and illnesses in deceased persons, checked the availability of anti-rabies vaccines in health facilities, and administered rabies knowledge and practice questionnaires to health workers. For categorical data, frequencies and proportions were determined.</p><p><strong>Results: </strong>There were 787 dog bite cases and six human rabies cases. Only a third (2/6) of the rabies cases were uploaded to the KHIS. The county used targeted dog vaccination, and samples were not collected from the biting dogs. Regarding the availability of human rabies vaccines, half (8/16) of the facilities had the human rabies vaccine, and 19% (3/16) had both the human rabies vaccine and rabies immunoglobulin (RIG). Rabies vaccine stock-outs were common at 73% (11/16). Only 25% (18/73) of the health workers reported their first action would be to clean the bite wound with running water and soap for 15 min. Additionally, 86% (54/63) did not know the recommended human rabies vaccine and RIG dosage and schedule, while 25% (18/73) of healthcare workers were satisfied with the existing information-sharing mechanisms between veterinary and human health departments for rabies prevention and control.</p><p><strong>Conclusions: </strong>There was underreporting of rabies cases, a lack of awareness of bite wound management at health facilities, and persistent stockouts of human rabies vaccines. We suggest training healthcare workers on animal bite case management and improving One Health information exchange.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"6"},"PeriodicalIF":3.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11809077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detections of antimicrobial resistance phenotypes and extended-spectrum beta-lactamase (ESBL)- producing Salmonella spps and Escherichia coli O157:H7 in raw vegetables and fruits from open markets in Jimma town, Ethiopia and evaluation of hygiene and handling practices of vendors.","authors":"Ahmed Zeynudin, Teshome Degefa, Tariku Belay, Jiru Batu Mumicha, Abdusemed Husen, Jafer Yasin, Abdulhakim Abamecha, Andreas Wieser, Mengistu Abayneh","doi":"10.1186/s42522-024-00125-5","DOIUrl":"10.1186/s42522-024-00125-5","url":null,"abstract":"<p><strong>Objectives: </strong>Despite of the health benefits of consumption of fresh vegetables and fruits, this product could be associated with food-borne bacterial pathogens, including infections with antibiotic-resistant strains especially in developing countries due to limited in knowledge, and hygienic practices. This study was conducted to provide evidence data on the rates of Salmonella spp. and E. coli O157:H7 contamination, the antimicrobial resistance profile, and extended-spectrum β-lactamase (ESBL)-producing strains in fresh vegetables and fruits sold in open-air markets at Jimma town, southwest Ethiopia. In addition, this study provided data on the hygiene and handling practices of vendors, which can help as impute to improve food safety and safeguard public health. A total of 242 salad samples were collected from three different kebeles and examined for the presence of Salmonella spp. and E. coli O157:H7 in the microbiology laboratory of Jimma University by using conventional microbiological techniques.</p><p><strong>Results: </strong>Out of 242 samples tested, 12.8% (31/242) were contaminated with Salmonella spp. and E. coli O157. Of these, Salmonella spp. was detected in 10.7% (26/242) of the tested samples, whereas Escherichia coli O157:H7 was found in 2.1% (5/242) of samples. Fifty-three-point-8% of Salmonella spp. were resistant to ampicillin, 42.3% to co-trimoxazole, 46.2% to tetracycline, and 26.9% resistance was observed against each of ceftriaxone and cefotaxime. 40% of E. coli O157:H7 isolates were resistant against ampicillin, amoxicillin-clavulanic acid, and co-trimoxazole. Only one isolate was resistant to ceftriaxone and cefotaxime, and no resistance was observed against ceftazidime, gentamicin, ciprofloxacin, chloramphenicol, and meropenem. Four Salmonella spp. and one E. coli O157:H7 isolate with a total of 5/31 (16.1%) isolates were confirmed as the ESBL producers. Multidrug resistance (MDR) was detected in 23.1% of Salmonella and 20.0% of E. coli O157:H7. Hygienic and handling practices of vendors were poor, which could contribute to contamination of vegetables and fruits in the area.</p><p><strong>Conclusions: </strong>Contamination of fresh salad vegetables with pathogenic bacteria could be a food safety concern in the study area. Hence, this finding suggests the need for attention by the concerned bodies to prevent the emergence and transmission of food-borne pathogens and antimicrobial-resistant strains through these food items in the study area.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"2"},"PeriodicalIF":3.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing surveillance for dengue fever in Oyo State, Nigeria - a one health approach.","authors":"Olawale Sunday Animasaun, Joseph Ojonugwa Shaibu, Busayo Kayode Akomolafe, Olamide Priscilla Animasaun, Piring'ar Mercy Niyang, Olukemi Titilope Olugbade, Akinfemi Oyewumi Akinyode, Ibukun Akinsola Omisakin, Adedapo Olufemi Adeogun, Rosemary Ajuma Audu","doi":"10.1186/s42522-024-00121-9","DOIUrl":"10.1186/s42522-024-00121-9","url":null,"abstract":"<p><strong>Background: </strong>Dengue fever (DF) poses a growing global threat, necessitating a comprehensive one-health approach to address its complex interplay between human, animal, and environmental factors. In Oyo State, Nigeria, the true burden of DF remains unknown due to underdiagnosis and misdiagnosis as malaria, exacerbated by poor health-seeking behavior, weak surveillance systems, and inadequate health infrastructure. Adopting a one-health approach is crucial to understanding the dynamics of DF transmission.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from January 2022 to April 2023 in 10 high-risk LGAs of Oyo State. It involved screening DENV in 289 febrile human blood samples and 1,015 Aedes species mosquitoes. Viral RNA from human and mosquito specimens was extracted and analyzed using RT-qPCR. A one-step lateral flow immunoassay cassette test kit detected DENV-specific IgM and IgG in humans. DENV IgM-positive participants were screened for Lassa Virus (LASV) to rule out coinfection due to an outbreak of Lassa fever. Mosquitoes recovered were morphologically identified and classified using appropriate taxonomical keys. Meteorological data was obtained from the Nigeria Meteorological Agency. Data was abridged as proportions and correlation analysis was performed.</p><p><strong>Result: </strong>The overall seroprevalence of DENV was 128/289 (44.2%) with 19/289 (6.6%) and 109/289 (37.7%) being IgM and IgG positive respectively. DENV was detected all year round with more cases in the rainy season. LASV and DENV coinfection were detected in a participant. DENV RT-qPCR analysis in febrile patients and mosquitoes was negative. There was a high abundance of Aedes aegypti (79.5%) in all the locations surveyed with Aedes albopictus (12.3%) detected in Ido LGA and Ibadan South-East LGA and Aedes simpsoni (9.1%) in Iwajowa LGA. DF shows moderate to strong positive correlations with Aedes mosquito population, humidity, and rainfall (r = 0.419-0.61, p < 0.05), and a negative correlation with temperature (r =-0.465, p < 0.05).</p><p><strong>Conclusion: </strong>The study reveals a significant burden of DENV in Oyo State. The presence of both IgM and IgG antibodies suggests past exposure and possible recent circulation of the virus. The co-detection of LASV and DENV in one participant highlights the likely potential for co-infection. Although DENV was not detected in febrile patients and mosquitoes through RT-qPCR, the high abundance of Aedes species underscores the risk of transmission. These findings emphasize the need for enhanced surveillance systems, strengthened laboratory services, targeted vector control, and increased awareness.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"5"},"PeriodicalIF":3.8,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective community engagement in one health research in Sub-Saharan Africa: a systematic review.","authors":"Sidney Sangong, Farrukh Ishaque Saah, Luchuo Engelbert Bain","doi":"10.1186/s42522-024-00126-4","DOIUrl":"10.1186/s42522-024-00126-4","url":null,"abstract":"<p><strong>Background: </strong>The one health (OH) approach, linking human, animal, and environmental health, relies on effective community engagement (CE), education, stewardship, and effective regional and global partnerships. For real impact, communities should be at the centre of research agenda setting and program implementation. This review aimed at synthesizing empirical evidence on how communities are involved in one health research. Specifically, the review aimed at documenting the extent of community involvement in one health research, as well as to identify the barriers and facilitators to effective community engagement in one health research in sub Saharan Africa.</p><p><strong>Methods: </strong>The study was a systematic review conducted using the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Empirical peer-reviewed research articles on community engagement in one health research published from January 2000 to September 2023 in English or French were retrieved from seven databases: MEDLINE, EMBASE, CINAHL, Cochrane Library, WHO Afro Library, the National Institute for Health Research, and African Journals Online databases. The extracted data from the included studies were analysed using a thematic synthesis approach.</p><p><strong>Results: </strong>The final review and synthesis included eight studies. The extent of CE in the one health research approach is quite limited. Two main best practices of CE in OH research were: 1) Awareness raising on OH research through social mobilization, rural outreach sensitization, and wide community assembly and 2) Building local capacity through community-based OH Training and Leadership workshops. The barriers to effective CE included: inadequate community research literacy levels, contextual disparities in CE, inadequate dissemination of research findings, language barriers and ineffective and uncoordinated stakeholder involvement.</p><p><strong>Conclusion: </strong>The review underscores the importance of effective CE in one health research. The best practices for CE in one health research are raising awareness and co-creation which should guide future initiatives. There are cultural, geographical, linguistic, and educational constraints that pose barriers to CE, requiring a more integrated and community-centric approach to one health research in SSA. An effective CE in one health research through this approach will ultimately lead to more effective responses and control of zoonotic disease outbreaks.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"4"},"PeriodicalIF":3.8,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zoonosis: social and environmental connections in the Mexico-United States border region.","authors":"Andrea Chaves, Hugo Mendoza, Angel Herrera, Mitsuri Pacheco-Zapata, Andrés M López-Pérez, Adriana Fernández, Milena Arguello-Sáenz, Audrey Arnal, Gerardo Suzán","doi":"10.1186/s42522-024-00120-w","DOIUrl":"10.1186/s42522-024-00120-w","url":null,"abstract":"<p><p>The emerging risks facing humanity have highlighted the need to address and prevent challenges through multilateral preventive strategies. The Mexico-United States (US) border is a region with great biological biodiversity and both countries shared a similar history and intense socioeconomic, and cultural interrelationships. Also, it has an extraordinary ecological contrast, resulting in an enormous biological diversity in a broad Nearctic-Neotropical transition zone. This dynamic region has important disparities due to the lack of bilateral strategies to face emerging issues (e.g., infectious diseases) in an integrated and holistic approach. In this context, we describe the various socio-ecosystemic contexts of the shared border and present different diseases transmitted, and different zoonoses that affect ecosystemic public health that must be addressed under collaborative schemes that can develop preventive policies under the One Health approach with emphasis on the Mexican zone. We describe the social determinants of health issues for the border, but we add ecological contexts infrequently studied in classical epidemiological approaches. Strategies towards One Health require international and multidisciplinary approaches that strengthen diagnostic capabilities, recognizing social, and environmental challenges. Recognizing these aspects will allow the establishment of joint monitoring, prevention, and mitigation strategies with benefits for both countries.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"3"},"PeriodicalIF":3.8,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11715514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142961069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phylogenetic inferences reveal multiple intra- and interhost genetic diversity among bat rabies viruses circulating in northeastern Brazil.","authors":"Larissa Leão F de Sousa, Mariana Dias Guilardi, Junior Olimpio Martins, Bruna Stefanie S Alves, Luiz Henrique S Tibo, Patrícia da Silva-Antunes, Gustavo Cabral-Miranda, Débora Bellini Caldeira, Paulo Eduardo Brandão, Fabrício Souza Campos, Luiz Mário R Janini, Ricardo Durães-Carvalho","doi":"10.1186/s42522-024-00124-6","DOIUrl":"https://doi.org/10.1186/s42522-024-00124-6","url":null,"abstract":"<p><strong>Background: </strong>Rabies, a lethal viral zoonotic disease, remains a significant global public health concern. In northeastern Brazil, in particular, its epidemiology is complex and dynamic, characterized by the presence of several reservoirs associated with human rabies infection.</p><p><strong>Methods: </strong>This study, conducted from June 2022 to July 2023, was part of a passive epidemiological surveillance initiative under Brazil's National Rabies Surveillance Program. It investigated the presence of Rhabdovirus (RhabV) in 356 postmortem chiropteran brain samples using three diagnostic techniques for rabies and conducted an evolutionary study on both pan-RhabV- and pan-LYSSAV-positive PCR samples. The samples were collected from 20 bat species and different locations in the State of Ceará, an endemic region for the rabies virus (RABV). Rabies-positive samples were further explored through Bayesian, genetic distance mapping and recombination analyses.</p><p><strong>Results: </strong>From a total of 356 samples collected, 43 (12.07%) were positive for direct immunofluorescence (DIF) and 40 (11.23%) for mouse intracerebral inoculation (MIT) tests. Among the positive results, 40 samples were confirmed by both DIF and MIT, while 13 (3.65%) had inconclusive results for one or both techniques. Molecular assays identified 38 rabies-positive samples (10.67%). Members of the Molossidae and Phyllostomidae families had the highest prevalence, highlighting the role of insectivorous and frugivorous bats in the cycle and dynamics of rabies transmission. Phylogenetic reconstructions revealed three distinct and well-supported clusters and clades, indicating the cocirculation of different RABV lineages in the region and shedding light on both intra- and interhost diversity. We also demonstrated genetic distance among the RABV clusters and inferred that their common ancestor originated in Europe, later diversifying across continents. No recombination breakpoints were identified.</p><p><strong>Conclusions: </strong>This study highlights the dynamic nature of RABV evolution within individual bat hosts, contributing to the understanding of the genetic diversity of RABV variants found in several bat species in northeastern Brazil. This study provides crucial insights into viral transmission dynamics within and between different host species and is essential for designing effective rabies control and prevention strategies tailored to endemic regions.</p>","PeriodicalId":94348,"journal":{"name":"One health outlook","volume":"7 1","pages":"1"},"PeriodicalIF":3.8,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}