Cancer Causes & Control最新文献

{"title":"Empowering cancer prevention with AI: unlocking new frontiers in prediction, diagnosis, and intervention.","authors":"Marianna-Foteini Dafni, Mohamed Shih, Agnes Zanotto Manoel, Mohamed Yousif Elamin Yousif, Stavroula Spathi, Chorya Harshal, Gaurang Bhatt, Swarali Yatin Chodnekar, Nicholas Stam Chune, Warda Rasool, Tungki Pratama Umar, Dimitrios C Moustakas, Robert Achkar, Harendra Kumar, Suhaila Naz, Luis M Acuña-Chavez, Konstantinos Evgenikos, Shaina Gulraiz, Eslam Salih Musa Ali, Amna Elaagib, Innocent H Peter Uggh","doi":"10.1007/s10552-024-01942-9","DOIUrl":"10.1007/s10552-024-01942-9","url":null,"abstract":"<p><p>Artificial intelligence is rapidly changing our world at an exponential rate and its transformative power has extensively reached important sectors like healthcare. In the fight against cancer, AI proved to be a novel and powerful tool, offering new hope for prevention and early detection. In this review, we will comprehensively explore the medical applications of AI, including early cancer detection through pathological and imaging analysis, risk stratification, patient triage, and the development of personalized prevention approaches. However, despite the successful impact AI has contributed to, we will also discuss the myriad of challenges that we have faced so far toward optimal AI implementation. There are problems when it comes to the best way in which we can use AI systemically. Having the correct data that can be understood easily must remain one of the most significant concerns in all its uses including sharing information. Another challenge that exists is how to interpret AI models because they are too complicated for people to follow through examples used in their developments which may affect trust, especially among medical professionals. Other considerations like data privacy, algorithm bias, and equitable access to AI tools have also arisen. Finally, we will evaluate possible future directions for this promising field that highlight AI's capacity to transform preventative cancer care.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":"353-367"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast cancer screening needs assessment in 19 Northern California counties: geography, poverty, and racial/ethnic identity composition.","authors":"Brittany L Morgan Bustamante, Diana Miglioretti, Theresa Keegan, Eric Stewart, Anshu Shrestha, Nuen Tsang Yang, Rosemary D Cress, Luis Carvajal-Carmona, Julie Dang, Laura Fejerman","doi":"10.1007/s10552-024-01943-8","DOIUrl":"10.1007/s10552-024-01943-8","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the area-level rate of breast cancers, the percentage of early-stage diagnoses (stage I-IIa), and associations between area-level measures of poverty, racial/ethnic composition, primary care shortage, and urban/rural/frontier status for the UC Davis Comprehensive Cancer Center (UCDCCC) catchment area.</p><p><strong>Methods: </strong>Using data from the SEER Cancer Registry of Greater California (2014-2018) and the California Department of Health Care Access and Information Medical Service Study Area, we conducted an ecological study in the UCDCCC catchment area to identify geographies that need screening interventions and their demographic characteristics.</p><p><strong>Results: </strong>The higher the percentage of the population identifying as Hispanic/Latino/Latinx, and the higher the percentage of the population below the 100% poverty level, the lower the odds of being diagnosed at an early-stage (OR = 0.98, 95% CI 0.96-0.99 and OR = 0.96, 95% CI 0.93-0.99, respectively). The association with poverty level was attenuated in the multivariable model when the Hispanic/Latino/Latinx population percentage was added. Several California counties had high poverty levels and differences in cancer stage distribution between racial/ethnic category groups. For all individuals combined, 65% was the lowest proportion of early-stage diagnoses for any geography. However, when stratified by racial/ethnic category, 11 geographies were below 65% for Hispanic/Latino/Latinx individuals, six for non-Hispanic Asian and Pacific Islander individuals, and seven for non-Hispanic African American/Black individuals, in contrast to one for non-Hispanic White individuals.</p><p><strong>Conclusions: </strong>Areas with lower percentages of breast cancers diagnosed at an early-stage were characterized by high levels of poverty. Variation in the proportion of early-stage diagnosis was also observed by race/ethnicity where the proportion of Hispanic/Latino/Latinx individuals was associated with fewer early-stage diagnoses.</p><p><strong>Impact: </strong>Results will inform the implementation of the UCDCCC mobile cancer prevention and early detection program, providing specific locations and populations to prioritize for tailored outreach, education, and screening.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":"369-377"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization and outcomes of serial cervical cancer screening in a National Breast and Cervical Cancer Early Detection Program (NBCCEDP) in a non-Medicaid expansion state.","authors":"Rubina Ratnaparkhi, Ahmed Ismail, Hope Krebill, Ian Cook, Melissa Javellana, Andrea Jewell, Lori Spoozak, Amanda Emerson, Megha Ramaswamy, Elizabeth Calhoun, Dinesh Pal Mudaranthakam","doi":"10.1007/s10552-024-01948-3","DOIUrl":"10.1007/s10552-024-01948-3","url":null,"abstract":"<p><strong>Purpose: </strong>Since 1990, the Centers for Disease Control and Prevention's National Breast and Cervical Cancer Early Detection Program (NBCCEDP) has offered free cervical cancer screening to low-income, uninsured patients, increasing single time point screening and early detection rates. Little is known about NBCCEDP's longitudinal effectiveness. The objective of this study was to assess utilization of Kansas's NBCCEDP, early detection works (EDW) for one-time versus serial screening and compare rates of cervical dysplasia between groups.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted among patients who received cervical cancer screening through EDW from 2001 to 2021. Demographic factors, Papanicolaou (Pap) test, and human papillomavirus (HPV) results were compared between patients with one screening versus multiple. Descriptive statistics were performed.</p><p><strong>Results: </strong>From 2014 to 2021, 3.71-7.06% of eligible patients completed screening through EDW annually. 17.4% of 58,582 eligible patients were up-to-date with screening in 2020. Rural patients and those under age forty were less likely to have EDW screening. Of 43,916 ever-screened patients, 14,638 (33.3%) received multiple screenings. 77% of patients did not have HPV testing; rates were lower in serially screened patients. Cervical dysplasia rates differed minimally between groups.</p><p><strong>Conclusion: </strong>Despite screening 24,017 patients over 7 years, EDW maintains up-to-date screening for under one-fourth of eligible Kansans. Young and rural patients less frequently access EDW. HPV testing is underutilized, which limits the negative predictive value of screening. Serial screening is largely used by low-risk patients currently. Identification and prioritization of serial screening in high risk could increase program impact.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":"409-420"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of outcomes by race among a population-based matched sample of multiple myeloma patients.","authors":"Breanna B Greteman, Michael H Tomasson, Amanda R Kahl, Madison M Wahlen, Melissa L Bates, Christopher Strouse, Mary E Charlton","doi":"10.1007/s10552-024-01938-5","DOIUrl":"10.1007/s10552-024-01938-5","url":null,"abstract":"<p><strong>Purpose: </strong>It is important to understand racial inequities in multiple myeloma treatment and survival, particularly in the Midwest where clear differences exist in cancer incidence and mortality. Since age and geographic location can greatly impact treatment and prognosis, matching patients on these characteristics can help identify reasons for outcome differences.</p><p><strong>Methods: </strong>Retrospective data from the Iowa Cancer Registry's Surveillance, Epidemiology, and End Results database were analyzed for adult patients diagnosed with first primary MM between 1/1/2010-12/31/2019. Matching procedures matched up to 4 White patients with each Black patient on age and city of residence. Demographic characteristics were compared, and Cox proportional hazards models were built to compare survival.</p><p><strong>Results: </strong>There were 1,845 patients in our overall sample, of which 85 were Black and 1,760 were White. There were 321 patients (74 Black, 247 White) that were matched. Black patients in the overall sample had decreased hazard for MM-specific death compared to White (HR = 0.50, 95% CI (0.43, 0.78)) when controlling for covariates. The decrease in MM-specific death in black patients was not statistically significant compared to matched controls (HR = 0.72, 95% CI (0.41, 1.27)). Treatment differences were not observed for either sample.</p><p><strong>Conclusion: </strong>We found that, despite large racial differences in MM incidence and mortality in Iowa, there are no survival differences when matched on age and city of residence. These data fail to detect large barriers to myeloma treatment in Iowa, and are useful for formulating potential screening and prevention strategies. Future research should also assess results in different geographic areas, investigate survival among older White patients in rural areas, and investigate other potential reasons for mortality differences between Black and White MM patients such as specific treatments received.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":"433-442"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic disparities: a more important risk factor for advanced-stage oral cancer in Florida than smoking?","authors":"Garrett Forman, Uche C Ezeh, Isabella Buitron, Sophia Peifer, Liana Shtern, Tonya Aaron, Abdurrahman Al-Awady, Isildinha M Reis, Erin R Kaye, Elizabeth Nicolli, David Arnold, Francisco Civantos, Ming Lee, Elizabeth Franzmann","doi":"10.1007/s10552-025-01992-7","DOIUrl":"https://doi.org/10.1007/s10552-025-01992-7","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the associations between sociodemographic factors with advanced-stage oral cavity cancer (OCC) presentation among Floridians.</p><p><strong>Methods: </strong>Demographic and cancer data on OCC patients (n = 7,826) diagnosed between 2010 and 2017 were retrieved from the Florida Cancer Data System (FCDS). Census tract median income and percentage of population with a bachelor's degree or higher were used to infer income and education. Pearson's chi-square tests of independence were used to compare sociodemographic factors between racial/ethnic groups and staging groups. Multinomial logistic regression analyzed predictors of advanced disease. Incidence and percent late-stage diagnosis versus income were mapped using ArcGIS Pro.</p><p><strong>Results: </strong>Among 5,252 cases analyzed: 5.7% were Black, 82.4% White Non-Hispanic, 61.5% male, 63.3% publicly insured, 6.5% uninsured, 58.7% current or former smokers, and 73.0% urban residents. Black patients were more likely to present with advanced disease, be single/unmarried, uninsured, and less likely to be former smokers. Male sex, Black race, non-married status, no insurance, Medicaid, VA/military insurance, and lower educational status were associated with increased risk of regional vs. early disease in multivariable analysis (MVA) (p < 0.05). These factors, in addition to Medicare, were associated with distant disease in MVA. Geospatial mapping revealed higher rates of regional and distant disease presentation in the Tampa Bay and Orlando areas.</p><p><strong>Conclusion: </strong>Black race, male sex, non-married status, lower education, Medicaid, VA/Military insurance and no insurance were associated with advanced OCC in Florida. Smoking status was not associated with advanced disease presentation after adjusting for sociodemographic variables.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproductive determinants of mammographic density in black women.","authors":"Zahna Bigham, Etienne X Holder, Angie Mae Rodday, Janis L Breeze, Kerrie P Nelson, Julie R Palmer, Karen M Freund, Kimberly A Bertrand","doi":"10.1007/s10552-025-01991-8","DOIUrl":"https://doi.org/10.1007/s10552-025-01991-8","url":null,"abstract":"<p><strong>Purpose: </strong>While high mammographic density has been established as one of the strongest, independent breast cancer risk factors, few studies have reported determinants of mammographic density in Black women. We aimed to identify reproductive-related characteristics associated with mammographic density in Black women.</p><p><strong>Methods: </strong>In data from a large mammography repository established in the Black Women's Health Study, we used Cumulus software to assess mammographic density from digital screening mammograms in 5,905 women ages 40-74. We used linear regression models to quantify the associations of parity, age at first birth, age at last birth, history of breastfeeding, and duration of breastfeeding with percent mammographic density. Models were adjusted for age, body mass index, and other breast cancer risk factors.</p><p><strong>Results: </strong>Among parous women age < 55 years, mean percent mammographic density was 2.0 percentage points (95% CI 0.3, 3.7) higher in women with a history of ≥ 3 births than in women with a history of only 1 birth. The magnitude of associations of number of births with mammographic density varied somewhat by age at first birth and age at mammography. We found no significant associations between other reproductive factors and mammographic density.</p><p><strong>Conclusion: </strong>In this large population of Black women, a higher number of births was modestly associated with higher percent mammographic density. This association may in part be influenced by age at first birth and age at mammography.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Mass Index and subjective cognitive decline among cancer survivors in the US: a cross-sectional analysis of a nationally representative survey.","authors":"Godfred O Antwi","doi":"10.1007/s10552-025-01990-9","DOIUrl":"https://doi.org/10.1007/s10552-025-01990-9","url":null,"abstract":"<p><strong>Objective: </strong>Despite the strong evidence suggesting significant relationships between Body Mass Index (BMI) and cognitive functioning in the general population, there is a dearth of research on this potential association in the cancer survivor sub-population. Therefore, utilizing a nationally representative sample, the current study seeks to examine the cross-sectional association between BMI and subjective cognitive decline (SCD) in adult cancer survivors in the US.</p><p><strong>Methods: </strong>The 2020, 2021, and 2022 Behavioral Risk Factor Surveillance System (BRFSS) surveys were used for the analysis. Logistic regression was performed to examine the odds of SCD in a sample of 20,739 cancer survivors, controlling for age, sex, race/ethnicity, marital status, level of education, employment status, general health status, and cigarette smoking status. All analyses were weighted to account for the complex study design and to produce nationally representative population estimates.</p><p><strong>Results: </strong>The prevalence of SCD among cancer survivors in this study was approximately 15%. Significant associations between BMI and SCD were found; compared to cancer survivors with normal weight, the odds of experiencing SCD were significantly greater for those with overweight (adjusted odds ratio [AOR] 1.22, 95% confidence interval [CI] 1.01-1.49) and obesity (AOR  1.24, 95%CI 1.02-1.51).</p><p><strong>Conclusion: </strong>Among cancer survivors in this study, unhealthy weight is associated with a higher risk of subjective cognitive decline. Underscoring the need for evidence-based interventions that support the cognitive health of adult cancer survivors, with a focus on those with unhealthy weight.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging technology and standardized institutional practices to mitigate disparities in breast cancer radiation therapy.","authors":"Jacob F Oyeniyi, Bailey A Loving, Muayad F Almahariq, Maha Saada Jawad, Joshua T Dilworth","doi":"10.1007/s10552-025-01978-5","DOIUrl":"https://doi.org/10.1007/s10552-025-01978-5","url":null,"abstract":"<p><strong>Objectives: </strong>Disparities in various dimensions, including racial, in breast cancer treatment and outcomes are well established. A recent multi-institutional study reported a higher mean heart dose (MHD) in Black and minority women compared to White women who underwent left-sided breast/chest wall irradiation which translated into excess cardiac events and mortality. We evaluated the MHD of women treated in our institution and investigated whether institution-wide measures including the use of readily available but inconsistently adopted technologies can mitigate this disparity.</p><p><strong>Methods: </strong>We identified 509 female patients treated with left-sided breast/chest wall irradiation with/without regional nodal irradiation (RNI). Details regarding cardiac dosimetry, deep-inspiratory breath-hold (DIBH) such as active breathing coordinator (ABC) use, breast size, internal mammary nodal (IMN) irradiation, and whether the treatment plan met boarding pass requirements and was peer reviewed were noted. MHD differences across racial groups were analyzed using Kruskal-Wallis test, while UVA and MVA linear regression analyses assessed influence of various factors on MHD.</p><p><strong>Results: </strong>MHD(Gy) was similar across racial groups; 1.38, 1.35, and 1.39 (p = 0.6) in Black, White, and other racial groups, respectively. Utilization of hypofractionation, cavity boosts, RNI, IMN irradiation, meeting boarding pass requirements, and peer review were similar. ABC usage (%) was 83/75/62 (p = 0.005), while median breast size(cc) was 1504/1904/1331 (p = 0.001) in White/Black/other women, respectively. On UVA and MVA, MHD differed with IMN treatment, boost and ABC use but not racial groups and varying breast sizes.</p><p><strong>Conclusion: </strong>Despite anatomical differences such as breast size, achieving similar cardiac dose is feasible across racial groups by uniformly utilizing appropriate technology such as ABC, with standardized boarding pass constraints, and peer review of all cases. Further studies to identify factors that may cause varied cardiac morbidity rates despite similar cardiac dosimetry among racial groups are warranted.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung cancer screening completion among patients using decision aids: a systematic review and meta-analysis.","authors":"Alexander Antigua-Made, Sabrina Nguyen, Ali Rashidi, Wen-Pin Chen, Argyrios Ziogas, Gelareh Sadigh","doi":"10.1007/s10552-025-01987-4","DOIUrl":"10.1007/s10552-025-01987-4","url":null,"abstract":"<p><strong>Purpose: </strong>Utilization of lung cancer screening (LCS) among eligible patients remains low at 16% in 2022. In this systematic review and meta-analysis we assessed the (a) LCS completion rate, and (b) intention to complete LCS, among patients who receive patient decision aids (PDAs).</p><p><strong>Methods: </strong>PubMed, Cochrane, Scopus, CINAHL, and Web of Science were searched for articles published in English between 1 January 2011, and 28 February 2023. Two independent reviewers selected randomized controlled trials and prospective cohort studies that reported PDA interventions targeting either LCS completion rate or intention to complete LCS. Quality appraisal and data extraction were performed independently by 2 reviewers using the National Heart, Lung, and Blood Institute quality assessment tool. A random-effects model meta-analysis was performed. Reporting followed the Preferred Reporting Items for Systematic Review and Meta-analyses guidelines.</p><p><strong>Results: </strong>Thirteen studies with 2,277 total participants (51.5% male) were included. The pooled LCS completion rate across all follow-up periods (range, 1-6 months) was 40% (95% confidence interval [CI], 15-65%) with an I² of 97% for heterogeneity. Pooled intention to complete LCS among patients who received PDA across all follow-up periods (same day to 3 months) was 57% (95% CI, 34% to 80%) with significant heterogeneity (I²) of 96% (p < 0.0001). No publication bias was identified.</p><p><strong>Conclusions: </strong>LCS completion and intention to complete LCS among patients who use PDAs is high. Our findings support the need to implement PDAs in clinical practice which could further facilitate shared decision-making and improve LCS uptake among eligible patients.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social media use and the relationship with colorectal cancer screening among foreign-born populations in the United States.","authors":"Joseph Atarere, Eugene Annor, Mariah Malak Bilalaga, Olachi Egbo, Greeshma N Gaddipati, Ramya Vasireddy, Boniface Mensah, Lewis Roberts","doi":"10.1007/s10552-025-01985-6","DOIUrl":"https://doi.org/10.1007/s10552-025-01985-6","url":null,"abstract":"<p><strong>Background: </strong>Social media (SM) has emerged as a tool for health-related usage among US adults, including cancer screening promotion. Here, we aimed to assess the differences in health-related SM use between US and foreign-born adults and the relationship between health-related SM use and colorectal (CRC) screening practices.</p><p><strong>Methods: </strong>Using data from the fifth edition of the National Cancer Institute's Health Information National Trends Survey (HINTS 5), cycle 2, we compared the differences in health-related SM use between US and foreign-born adults and the effects of SM use on CRC screening by country of birth. We included adults aged 50-75 and excluded participants with a history of CRC. The primary endpoint was CRC screening, which was determined by self-reported CRC screening using colonoscopy, sigmoidoscopy, or stool occult blood testing.</p><p><strong>Results: </strong>Our study included 1,812 adults, of whom 236 (13.0%) were foreign-born. Most participants (72.1%) reported undergoing CRC screening. Interestingly, we found no discernible difference in health-related SM use [odds ratio [OR] 0.91; 95% CI (0.49, 1.69)] between US and foreign-born adults. Furthermore, our analysis revealed that SM use did not influence CRC screening practices among either group (US-born: 0.88 [95% CI: 0.50, 1.52], foreign-born 0.52 [0.10, 2.51]).</p><p><strong>Conclusion: </strong>Contrary to previous studies, which showed a positive relationship between SM use and satisfactory health-related practices, we found that although foreign-born adults use SM as much as US-born adults, there was no significant relationship between SM use and CRC screening.</p>","PeriodicalId":9432,"journal":{"name":"Cancer Causes & Control","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}