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Task Shifting in Cardiac Catheterization to Sustain Physicians and Acute Coronary Syndrome Response Centers - Findings From the 2024 Japanese Circulation Society Chugoku-Shikoku Regional Survey. 心导管插入术的任务转移,以维持医生和急性冠状动脉综合征反应中心——来自2024年日本循环学会Chugoku-Shikoku地区调查的结果
Circulation reports Pub Date : 2024-10-26 eCollection Date: 2024-12-10 DOI: 10.1253/circrep.CR-24-0100
Takeshi Suetomi, Noriko Fukue, Mari Ishida, Makiko Taniyama, Natsuko Mukai-Yatagai, Takahiro Sakamoto, Tomoko Tamada, Tomomi Matsuura, Kazuaki Tanabe, Yukiko Nakano
{"title":"Task Shifting in Cardiac Catheterization to Sustain Physicians and Acute Coronary Syndrome Response Centers - Findings From the 2024 Japanese Circulation Society Chugoku-Shikoku Regional Survey.","authors":"Takeshi Suetomi, Noriko Fukue, Mari Ishida, Makiko Taniyama, Natsuko Mukai-Yatagai, Takahiro Sakamoto, Tomoko Tamada, Tomomi Matsuura, Kazuaki Tanabe, Yukiko Nakano","doi":"10.1253/circrep.CR-24-0100","DOIUrl":"10.1253/circrep.CR-24-0100","url":null,"abstract":"<p><strong>Background: </strong>Sustainability of the 24/7 acute coronary syndrome response system is at risk due to the Work Style Reform for physicians.</p><p><strong>Methods and results: </strong>A survey of 93 facilities in Chugoku-Shikoku region found that 30% of facilities expected acute coronary syndrome services to be restricted due to the Work Style Reform. Approximately 35% had implemented task shifting, which reduced physicians' workload by 30% and improved team care.</p><p><strong>Conclusions: </strong>Task shifting improved the working environment. However, various barriers to implementation were also identified. Further investigation is needed to achieve a balance between the Work Style Reform and sustainability of the acute coronary syndrome response system.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 12","pages":"592-597"},"PeriodicalIF":0.0,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioprosthetic Valve Positions in Patients With Atrial Fibrillation - Insights From the BPV-AF Registry. 心房颤动患者的生物人工瓣膜位置--来自 BPV-AF 登记的启示。
Circulation reports Pub Date : 2024-10-19 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0110
Yuki Obayashi, Makoto Miyake, Misa Takegami, Masashi Amano, Takeshi Kitai, Tomoyuki Fujita, Tadaaki Koyama, Hidekazu Tanaka, Kenji Ando, Tatsuhiko Komiya, Masaki Izumo, Hiroya Kawai, Kiyoyuki Eishi, Kiyoshi Yoshida, Takeshi Kimura, Ryuzo Nawada, Tomohiro Sakamoto, Yoshisato Shibata, Toshihiro Fukui, Kenji Minatoya, Kenichi Tsujita, Yasushi Sakata, Masayuki Fukuzawa, Kyokun Uehara, Toshihiro Tamura, Kunihiro Nishimura, Yutaka Furukawa, Chisato Izumi
{"title":"Bioprosthetic Valve Positions in Patients With Atrial Fibrillation - Insights From the BPV-AF Registry.","authors":"Yuki Obayashi, Makoto Miyake, Misa Takegami, Masashi Amano, Takeshi Kitai, Tomoyuki Fujita, Tadaaki Koyama, Hidekazu Tanaka, Kenji Ando, Tatsuhiko Komiya, Masaki Izumo, Hiroya Kawai, Kiyoyuki Eishi, Kiyoshi Yoshida, Takeshi Kimura, Ryuzo Nawada, Tomohiro Sakamoto, Yoshisato Shibata, Toshihiro Fukui, Kenji Minatoya, Kenichi Tsujita, Yasushi Sakata, Masayuki Fukuzawa, Kyokun Uehara, Toshihiro Tamura, Kunihiro Nishimura, Yutaka Furukawa, Chisato Izumi","doi":"10.1253/circrep.CR-24-0110","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0110","url":null,"abstract":"<p><strong>Background: </strong>Data on the impact of valve position on clinical outcomes in patients with atrial fibrillation (AF) and bioprosthetic valves (BPVs) are limited.</p><p><strong>Methods and results: </strong>The BPV-AF Registry was a multicenter, prospective, observational study involving 894 patients with BPVs and AF. In this post-hoc substudy, patients were classified according to BPV position: aortic (n=588; 65.8%), mitral (n=195; 21.8%), or both (n=111; 12.4%). The primary outcome was a composite of stroke/systemic embolism, major bleeding, heart failure requiring hospitalization, all-cause death, or BPV reoperation. During a mean follow up of 15.3±4.0 months, the primary outcome occurred in 90 (15.3%) patients (12.7/100 patient-years) in the aortic group, 25 (12.8%; 10.2/100 patient-years) in the mitral group, and 16 (14.4%; 11.8/100 patient-years) in the both-valves group (log-rank P=0.621). The unadjusted and adjusted risks were not significant for the mitral and both-valves groups relative to the aortic group (unadjusted hazard ratio [95% confidence interval] 0.80 [0.52-1.25] and 0.92 [0.54-1.57]; adjusted hazard ratio 0.89 [0.51-1.54] and 1.10 [0.58-2.09], respectively). There was no significant difference in the incidence of stroke/systemic embolism or major bleeding among the 3 groups (log-rank P=0.651 and 0.156, respectively).</p><p><strong>Conclusions: </strong>In patients with BPVs and AF, the risk for the composite outcome was comparable regardless of the BPV position.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"521-528"},"PeriodicalIF":0.0,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of Angiographic Deterioration Following Inframalleolar Angioplasty and Its Impact on Outcomes in Patients With Chronic Limb-Threatening Ischemia Requiring Repeat Intervention. 需要再次介入治疗的慢性肢体缺血患者接受无瓣膜血管成形术后血管造影恶化的发生率及其对疗效的影响
Circulation reports Pub Date : 2024-10-18 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0103
Yosuke Hata, Osamu Iida, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takuya Tsujimura, Yasuhiro Matsuda, Hiroyuki Uematsu, Sho Nakao, Masaya Kusuda, Wataru Ariyasu, Toshiaki Mano
{"title":"Incidence of Angiographic Deterioration Following Inframalleolar Angioplasty and Its Impact on Outcomes in Patients With Chronic Limb-Threatening Ischemia Requiring Repeat Intervention.","authors":"Yosuke Hata, Osamu Iida, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takuya Tsujimura, Yasuhiro Matsuda, Hiroyuki Uematsu, Sho Nakao, Masaya Kusuda, Wataru Ariyasu, Toshiaki Mano","doi":"10.1253/circrep.CR-24-0103","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0103","url":null,"abstract":"<p><strong>Background: </strong>Clinical impact of inframalleolar (IM) angioplasty in patients with chronic limb-threatening ischemia (CLTI) is still controversial.</p><p><strong>Methods and results: </strong>This single-center, retrospective study included 168 patients with CLTI and tissue loss who underwent angioplasty for IM lesions. Angiographic follow up was performed at reintervention between April 2010 and December 2020. The outcome measure was the incidence of angiographic deterioration characterized by severe restenosis or occlusion of mildly stenotic lesions, occlusion of severely stenotic lesions, or extension of the occlusion length at reintervention. Angiographic deterioration was observed in 47.7% of patients, with the majority attributed to occlusion in severely stenotic lesions. Multivariate analysis revealed that a distal reference vessel diameter ≤1.0 mm in the initial angioplasty (hazard ratio 1.91 [95% confidence interval 1.20-3.04]; P=0.006) was significantly associated with angiographic deterioration of IM lesions at reintervention.</p><p><strong>Conclusions: </strong>Angiographic deterioration occurred in approximately half of the patients with CLTI who underwent IM angioplasty and reintervention.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"514-520"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phase III Cardiac Rehabilitation: Ambulatory Heart Groups - A Model From Germany. 第三阶段心脏康复:非住院心脏小组--德国模式。
Circulation reports Pub Date : 2024-10-11 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0106
Roland Nebel
{"title":"Phase III Cardiac Rehabilitation: Ambulatory Heart Groups - A Model From Germany.","authors":"Roland Nebel","doi":"10.1253/circrep.CR-24-0106","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0106","url":null,"abstract":"<p><p>Approximately 7,000 ambulatory (outpatient) heart groups (AHG) with 125,000 patients who are physically active on a regular basis have been established in Germany since the mid-1960s. Following phase II cardiac rehabilitation (CR), patients in an AHG aim to meet their set CR goals in groups of up to 20 participants under the instruction of a competent exercise therapist, and with regular attendance by a physician. Physical activity is the dominant aspect; psychosocial and educative elements are integrated to stabilize secondary cardiovascular prevention. Patients are legally entitled by German rehabilitation law to participate in AHGs. According to current studies, only 13-40% of all patients attend an AHG after phase II CR. In 2019, special AHGs for patients with high cardiovascular risk (chronic heart failure) were established. In the future, special emphasis needs to be placed on the recruitment of more patients into AHGs, particularly for the known under-represented groups (i.e., women, older patients, patients with low socioeconomic status). Furthermore, AHGs have to be established for patients with special needs (e.g., adults with congenital heart diseases). To date, the efficiency of AHG participation has still not been sufficiently investigated. A case-control study analyzing the long-term results of AHG participation reported an improvement in physical performance, as well as a reduction in cardiovascular morbidity (54%) and medical costs (approximately 47%). More superior investigations in this field are needed.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"489-494"},"PeriodicalIF":0.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypoxic Spell in Pediatric Patient With Repaired Tetralogy of Fallot. 法洛氏四联症修补术小儿患者的缺氧症状
Circulation reports Pub Date : 2024-10-09 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0104
Seigo Okada, Yuji Ohnishi, Takahiro Motonaga, Jun Muneuchi, Yoshie Ochiai
{"title":"Hypoxic Spell in Pediatric Patient With Repaired Tetralogy of Fallot.","authors":"Seigo Okada, Yuji Ohnishi, Takahiro Motonaga, Jun Muneuchi, Yoshie Ochiai","doi":"10.1253/circrep.CR-24-0104","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0104","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"536-537"},"PeriodicalIF":0.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Message From the Editor-in-Chief - Special Issue on the 30th Annual Scientific Meeting of the Japanese Association of Cardiac Rehabilitation. 主编寄语--日本心脏康复协会第 30 届科学年会特刊。
Circulation reports Pub Date : 2024-10-07 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-66-0018
Masataka Sata
{"title":"Message From the Editor-in-Chief - Special Issue on the 30th Annual Scientific Meeting of the Japanese Association of Cardiac Rehabilitation.","authors":"Masataka Sata","doi":"10.1253/circrep.CR-66-0018","DOIUrl":"https://doi.org/10.1253/circrep.CR-66-0018","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"473-476"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Focusing on Sedentary Behavior in Comprehensive Cardiac Rehabilitation. 在综合心脏康复治疗中关注久坐行为。
Circulation reports Pub Date : 2024-10-05 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0098
Kazuhiro P Izawa, Koichiro Oka
{"title":"Focusing on Sedentary Behavior in Comprehensive Cardiac Rehabilitation.","authors":"Kazuhiro P Izawa, Koichiro Oka","doi":"10.1253/circrep.CR-24-0098","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0098","url":null,"abstract":"<p><p>In recent years, the adverse effects of prolonged sedentary behavior in daily life, so-called 'sitting too much', on health have been pointed out. Sedentary behavior is defined as 'all waking behavior in which the energy expenditure in a sitting, semi-recumbent, or recumbent position is 1.5 metabolic equivalents or less'. Even if a person engages in the level of physical activity recommended in the guidelines, sitting for too long at other times may increase the risk of developing various diseases and death. For patients with cardiovascular disease, a comprehensive cardiac rehabilitation program that systematically includes not only medical treatment but also exercise therapy, patient education, and disease management is extremely important. Also, differences in sedentary behavior during the acute and recovery phases are known to affect physical function and activities of daily living at the time of hospital discharge. Here, we discuss cardiac rehabilitation that addresses sedentary behavior and review the previous related research.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"481-488"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Coexisting Constipation and Heart Failure Readmission in Patients With Heart Failure - A Nationwide Database Study. 心力衰竭患者并存便秘与心力衰竭再入院之间的关系--一项全国性数据库研究。
Circulation reports Pub Date : 2024-10-04 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0060
Toshiaki Isogai, Kojiro Morita, Akira Okada, Nobuaki Michihata, Hiroki Matsui, Atsushi Miyawaki, Hideo Yasunaga
{"title":"Association Between Coexisting Constipation and Heart Failure Readmission in Patients With Heart Failure - A Nationwide Database Study.","authors":"Toshiaki Isogai, Kojiro Morita, Akira Okada, Nobuaki Michihata, Hiroki Matsui, Atsushi Miyawaki, Hideo Yasunaga","doi":"10.1253/circrep.CR-24-0060","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0060","url":null,"abstract":"<p><strong>Background: </strong>Constipation often coexists with heart failure (HF) and can cause increased blood pressure variability, which may increase the risk of repeated HF admissions. However, large-scale contemporary data regarding the prognostic effect of constipation in patients with HF are lacking.</p><p><strong>Methods and results: </strong>We retrospectively identified 556,792 patients admitted for HF for the first time and discharged alive in the fiscal years 2016-2021 using the Japanese Diagnosis Procedure Combination database. Constipation was defined as continued use of laxatives after discharge. We examined the association between constipation and 1-year HF readmission. The prevalence of constipation was 22.0% (n=122,670), which remained stable over the 6 years. Patients with constipation were older (82.7±10.1 vs. 79.3±12.8 years), more often female (53.5% vs. 48.0%), and received medications for HF more frequently at discharge compared with those without constipation. In the multivariable Cox proportional hazards model, constipation was significantly associated with a higher incidence of 1-year HF readmission (24.0% vs. 18.6%; adjusted hazard ratio [HR] 1.08; 95% confidence interval [CI] 1.06-1.10). This result was consistent with the result from the Fine-Gray model accounting for competing risk of death (subdistribution HR 1.08; 95% CI 1.06-1.09).</p><p><strong>Conclusions: </strong>Constipation was associated with a higher risk of HF readmission after the first episode of HF hospitalization. Given the detrimental effect of constipation, further efforts are warranted to decrease constipation-related risk in patients with HF.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"529-535"},"PeriodicalIF":0.0,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Holding Health Seminars at Acute Care Hospitals and Fitness Clubs to Prevent Heart Failure. 在急症医院和健身俱乐部举办健康讲座,预防心力衰竭。
Circulation reports Pub Date : 2024-09-28 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0097
Yuta Nakaya, Yugo Horii, Kazuma Tanimoto
{"title":"Holding Health Seminars at Acute Care Hospitals and Fitness Clubs to Prevent Heart Failure.","authors":"Yuta Nakaya, Yugo Horii, Kazuma Tanimoto","doi":"10.1253/circrep.CR-24-0097","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0097","url":null,"abstract":"<p><p>Ehime Prefecture has the highest heart failure mortality rate among men and women in Japan. Healthy life expectancy is low nationwide, which may be related to sarcopenia and frailty. Uwajima City contains a progresses aging of the population in the Ehime Prefecture. Therefore, preventing heart failure requires treatment and patient education not only for the underlying disease, but also for the complications associated with aging, such as sarcopenia and frailty. In 2020, we began working with the fitness club LocomoK.O to focus on prevention after the onset of disease and prevention before onset. We have commenced surveys of healthy older adults living in the community in Uwajima City, including the Short Physical Performance Battery, physical functions such as handgrip strength, and body composition assessment using in-body tests. The data showed that the rate of sarcopenia was extremely high, at 70% in patients with acute heart failure and 39% in the healthy older group, and that 24% of patients with acute heart failure had severe sarcopenia. Based on the collected data, we started health seminars in 2023 to educate citizens about the disease to prevent the onset and recurrence of heart disease, which is in line with the current situation in Uwajima City. We hope that our activities will help those struggling with local medical care.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"477-480"},"PeriodicalIF":0.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of Native T1 in Cardiac Magnetic Resonance Imaging and Echocardiographic Strain Parameters for Detecting Early Cardiac Involvement in Fabry Cardiomyopathy. 心脏磁共振成像中的原位 T1 和超声心动图应变参数对检测法布里心肌病早期心脏受累的有用性
Circulation reports Pub Date : 2024-09-26 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0068
Shoko Nakagawa, Masashi Amano, Yurie Tamai, Ayaka Mizumoto, Shinichi Kurashima, Yuki Irie, Kenji Moriuchi, Takahiro Sakamoto, Makoto Amaki, Hideaki Kanzaki, Yoshiaki Morita, Takeshi Kitai, Chisato Izumi
{"title":"Usefulness of Native T1 in Cardiac Magnetic Resonance Imaging and Echocardiographic Strain Parameters for Detecting Early Cardiac Involvement in Fabry Cardiomyopathy.","authors":"Shoko Nakagawa, Masashi Amano, Yurie Tamai, Ayaka Mizumoto, Shinichi Kurashima, Yuki Irie, Kenji Moriuchi, Takahiro Sakamoto, Makoto Amaki, Hideaki Kanzaki, Yoshiaki Morita, Takeshi Kitai, Chisato Izumi","doi":"10.1253/circrep.CR-24-0068","DOIUrl":"10.1253/circrep.CR-24-0068","url":null,"abstract":"<p><strong>Background: </strong>Non-invasive diagnosis of disease stage in Fabry cardiomyopathy with multimodality imaging is pivotal when deciding on the appropriate time to initiate enzyme replacement therapy. However, this approach has not been well established.</p><p><strong>Methods and results: </strong>We enrolled 14 patients with Fabry disease. All patients were evaluated using echocardiography and contrast cardiac magnetic resonance (CMR), and were divided into either an early-stage group without left ventricular hypertrophy (LVH; wall thickness >12 mm) or late gadolinium enhancement (LGE; n=7; median age 37 years; 4 female), or an advanced-stage group with LVH and/or LGE (n=7; median age 66 years; 7 female). Strain data from echocardiography and T1 mapping on CMR were compared between the groups. In the advanced-stage group, all strain data were impaired. In the early-stage group, localized longitudinal strain in the basal posterolateral segment was already reduced but both localized and global circumferential strain remained preserved. On CMR analysis, global and localized native T1 shortening were observed in the early-stage group, but were pseudo-normalized in the advanced-stage group. In logistic regression analysis, localized circumferential strain had significant diagnostic value for differentiating between early- and advanced stage (P=0.037) and significantly improved the predictive power of the model containing localized native T1 in CMR.</p><p><strong>Conclusions: </strong>A combination of localized native T1 in CMR and echocardiographic strain parameters could be useful for staging Fabry cardiomyopathy.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"456-464"},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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