{"title":"Lumbar-Type Hybrid Assistive Limb Improves Short Physical Performance Battery for Aged Patients With Decompensated Heart Failure in Cardiac Rehabilitation.","authors":"Kazuya Yamamoto, Hiroyuki Miura, Yoshiyuki Sankai, Chiaki Yokota, Makoto Murata","doi":"10.1253/circrep.CR-25-0107","DOIUrl":"10.1253/circrep.CR-25-0107","url":null,"abstract":"<p><strong>Background: </strong>Unlike the outpatient cardiac rehabilitation (CR) program for chronic heart failure (HF), the acute-phase inpatient CR program is not well established. We aimed to examine whether CR using lumbar-type hybrid assistive limb (HAL; lumbar HAL-CR) therapy improves physical functions in hospitalized aged HF patients.</p><p><strong>Methods and results: </strong>Decompensated and hospitalized HF patients were recruited from 2018 to 2019. As soon as possible after the decompensated HF phase, during the same hospitalization, participants underwent 40-min daily sessions of sit-to-stand and squat exercises with the lumbar-type HAL (lumbar HAL-CR program). The outcome measure was the score on the Short Physical Performance Battery (SPPB) before and after lumbar HAL-CR therapy. Twenty-eight HF patients (median age 84.5 years; 18 males) were enrolled. The median number of lumbar HAL-CR therapy sessions was 5.0. The SPPB score (7.0 [5.3-8.8] to 9.0 [7.0-11.0] points; P<0.001) and quadriceps isometric strength (0.25 [0.22-0.38] to 0.30 [0.26-0.37] kgf/kg; P=0.040) were significantly improved. Patients with lower nutrition status had more improvement in SPPB score.</p><p><strong>Conclusions: </strong>For the inpatient CR program, lumbar-type HAL therapy improved physical functions in elderly HF patients. Lumbar-type HAL therapy may improve physical functions in aged HF patients within the current short-term period of hospitalization for acute-phase HF.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"774-781"},"PeriodicalIF":1.1,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic Significance of Peripheral Monocyte Counts in Patients With Chronic Heart Failure.","authors":"Atsushi Nozuhara, Eiichiro Yamamoto, Takashi Komorita, Daisuke Sueta, Koichiro Fujisue, Fumi Oike, Masanobu Ishii, Hiroki Usuku, Shinsuke Hanatani, Satoshi Araki, Hirofumi Soejima, Yasushi Matsuzawa, Yasuhiro Izumiya, Kenichi Tsujita","doi":"10.1253/circrep.CR-25-0102","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0102","url":null,"abstract":"<p><strong>Background: </strong>The pathophysiological condition between heart failure (HF) with preserved left ventricular ejection fraction (LVEF; HFpEF) and non-HFpEF is different. To elucidate the prognostic value of monocytes, as representatives of the innate immune system, we examined the association between peripheral monocyte counts and future HF-related events in patients with HF.</p><p><strong>Methods and results: </strong>A total of 678 patients with HF referred for hospitalization was enrolled. These patients were categorized into 2 groups according to LVEF: HFpEF, and non-HFpEF. Based on the median monocyte values, we then defined the high monocyte group as having peripheral monocyte counts ≥363/mm<sup>3</sup> in patients with non-HFpEF, and as peripheral monocyte counts ≥322/mm<sup>3</sup> in patients with HFpEF. There were 200 patients with non-HFpEF and 478 with HFpEF. Based on receiver operating characteristic analysis, patients with non-HFpEF who were in the high peripheral monocyte group had a significantly higher risk of HF-related events compared with those in the low peripheral monocyte group. In contrast, the high and low peripheral monocyte groups for patients with HFpEF had no significant difference in HF-related events. Multivariate Cox hazard analysis identified high peripheral monocyte counts as an independent and significant predictor of future HF-related events only in patients with non-HFpEF.</p><p><strong>Conclusions: </strong>High peripheral monocyte count was an independent and incremental predictor of HF-related events in non-HFpEF, rather than in patients with HFpEF.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"913-921"},"PeriodicalIF":1.1,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Invasive Strategy in Non-ST-Elevation Acute Coronary Syndrome With Congestive Heart Failure - A Systematic Review and Meta-Analysis.","authors":"Kiyotaka Hao, Takuya Taniguchi, Sunao Kojima, Marina Arai, Rie Aoyama, Kazuya Tateishi, Yuichiro Minami, Masashi Yokose, Akihito Tanaka, Kunihiro Matsuo, Junichi Yamaguchi, Toshiaki Mano, Takeshi Yamamoto, Naoki Nakayama, Hiroyuki Hanada, Katsutaka Hashiba, Takahiro Nakashima, Toru Kondo, Teruo Noguchi, Yasushi Tsujimoto, Tetsuya Matoba, Toshikazu Funazaki, Yoshio Tahara, Hiroshi Nonogi, Migaku Kikuchi","doi":"10.1253/circrep.CR-25-0104","DOIUrl":"10.1253/circrep.CR-25-0104","url":null,"abstract":"<p><strong>Background: </strong>Congestive heart failure (CHF) is associated with worse clinical outcomes in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS); however, the optimal timing of invasive intervention in NSTE-ACS with CHF remains unclear. In this study, we assessed the impact of early vs. delayed invasive strategies on mortality and cardiac events by synthesizing a systematic review of randomized controlled trials of patients with NSTE-ACS.</p><p><strong>Methods and results: </strong>We searched MEDLINE, CENTRAL, and the Web of Science for randomized controlled trials comparing early and delayed invasive strategies in patients with NSTE-ACS and CHF, published before February 2023. Observational studies were excluded. The primary endpoint was a composite of all-cause mortality and myocardial infarction at 2 years. Two eligible studies, including 310 participants, were identified. The primary endpoint occurred in 40 (24.5%) of 163 patients in the early invasive strategy group, compared with 39 (26.5%) of 147 patients in the delayed invasive strategy group, and the effect of an early invasive strategy on the primary outcome was uncertain (risk ratio 0.95 [95% confidence interval 0.66-1.37]). The certainty of the evidence was rated very low.</p><p><strong>Conclusions: </strong>The effects of an early invasive strategy in patients with NSTE-ACS and CHF remains uncertain, with no clear reduction in composite outcome of mortality and myocardial infarction at 2 years compared with delayed intervention.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"697-704"},"PeriodicalIF":1.1,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Benefits of Coronary Computed Tomography Angiography for Evaluating Low-Risk Patients With Non-ST-Elevation Acute Coronary Syndrome in the Emergency Department - Systematic Review and Meta-Analysis.","authors":"Kazuya Tateishi, Toshiaki Mano, Rie Aoyama, Kiyotaka Hao, Takuya Taniguchi, Sunao Kojima, Marina Arai, Yuichiro Minami, Masashi Yokose, Toru Kondo, Akihito Tanaka, Kunihiro Matsuo, Junichi Yamaguchi, Takeshi Yamamoto, Naoki Nakayama, Hiroyuki Hanada, Katsutaka Hashiba, Takahiro Nakashima, Tetsuya Matoba, Yoshio Tahara, Hiroshi Nonogi, Teruo Noguchi, Yasushi Tsujimoto, Migaku Kikuchi","doi":"10.1253/circrep.CR-25-0114","DOIUrl":"10.1253/circrep.CR-25-0114","url":null,"abstract":"<p><strong>Background: </strong>The utility of coronary computed tomography angiography (CCTA) in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS), particularly among low-risk individuals presenting to the emergency department (ED), remains unclear. We conducted a systematic review to assess the clinical benefits of CCTA in low-risk patients presenting to the ED with chest pain.</p><p><strong>Methods and results: </strong>A systematic search of MEDLINE, CENTRAL, and Web of Science was performed for randomized controlled trials (RCTs) published up to March 23, 2023, comparing CCTA performed in the ED with standard care in low-risk patients with NSTE-ACS. Low-risk status was defined as resolved symptoms at ED presentation and no troponin elevation or ischemic ECG changes. Seven RCTs were extracted from the databases. No significant differences were observed between the CCTA and standard care groups in all-cause mortality, non-fatal myocardial infarction, ED revisits, or radiation exposure. However, hospital length of stay was significantly shorter and healthcare costs were slightly lower in the CCTA group. Conversely, revascularization and invasive coronary angiography were significantly more frequent in this group.</p><p><strong>Conclusions: </strong>In low-risk patients with NSTE-ACS, CCTA performed in the ED did not reduce adverse clinical events but was associated with shorter hospital stays and marginally reduced healthcare costs. These findings suggest that CCTA may be a useful tool that supports the safe and early discharge of selected patients.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"705-714"},"PeriodicalIF":1.1,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Grip Strength Is an Independent Predictor of Early Ambulation in Patients After Elective Cardiac Surgery With Extracorporeal Circulation.","authors":"Shun Yoshihara, Yasunori Suematsu, Reiko Teshima, Ippo Otoyama, Masaomi Fujita, Shigenori Nishimura, Ayaka Aramaki, Yuka Nakashima, Yutaro Inoue, Kanta Fujimi, Hideichi Wada, Shin-Ichiro Miura","doi":"10.1253/circrep.CR-25-0058","DOIUrl":"10.1253/circrep.CR-25-0058","url":null,"abstract":"<p><strong>Background: </strong>Grip strength is a simple predictor of cardiovascular events and their prognosis. Early ambulation is related to an increase in functional independence, shortening of hospital stay, and a decrease in the need for readmission in patients with cardiovascular disease. However, little is known about the relationship between grip strength and early ambulation after cardiac surgery.</p><p><strong>Methods and results: </strong>In this observational study, 92 patients who underwent scheduled cardiac surgery with extracorporeal circulation without unexpected complications and in whom grip strength was measured before surgery were included. We divided them into 48 low and 44 preserved grip strength groups according to the criterion for frailty and sarcopenia. Age, the percentage of females, and the New York Heart Association classification in the low grip strength group were significantly higher than in the preserved grip strength group. All of the measures of functional status were significantly low in the low grip strength group. There were no significant differences in perioperative procedures between the groups. In-hospital outcomes were poorer, step-ups of rehabilitation were significantly later and the hospitalization stays were significantly longer in the low grip strength group. In the multiple regression analysis, grip strength was an independent predictor of early ambulation.</p><p><strong>Conclusions: </strong>The results suggest that grip strength is an independent predictor of early ambulation in patients after cardiac surgery with extracorporeal circulation.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"784-790"},"PeriodicalIF":1.1,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Priorities for Early Revascularization or Introduction of Mechanical Circulatory Support in Patients With Acute Coronary Syndrome Complicated by Cardiogenic Shock - A Systematic Review and Meta-Analysis.","authors":"Aya Katasako-Yabumoto, Kazuo Sakamoto, Katsutaka Hashiba, Takeshi Yamamoto, Naoki Nakayama, Hiroyuki Hanada, Takahiro Nakashima, Jin Kirigaya, Tomoko Ishizu, Yumiko Hosoya, Toru Kondo, Yusuke Okazaki, Masahiro Yamamoto, Takumi Osawa, Marina Arai, Yoshio Tahara, Hiroshi Nonogi, Teruo Noguchi, Yasushi Tsujimoto, Migaku Kikuchi, Tetsuya Matoba","doi":"10.1253/circrep.CR-25-0098","DOIUrl":"10.1253/circrep.CR-25-0098","url":null,"abstract":"<p><strong>Background: </strong>The optimal timing for mechanical circulatory support (MCS) initiation in patients with acute myocardial infarction complicated by cardiogenic shock (CS) is unknown, so in this study we analyzed whether MCS implementation before percutaneous coronary intervention (PCI) is associated with better outcomes compared to after PCI.</p><p><strong>Methods and results: </strong>We conducted a systematic review and meta-analysis using a random-effects model to account for potential heterogeneity. Risk ratios and 95% confidence intervals were used for dichotomous outcomes. PubMed, Web of Science, and CENTRAL were searched up to April 30, 2023. Certainty of evidence was evaluated according to the Risk of Bias in Non-Randomized Studies of Interventions-I tool. A total of 14 observational studies met the inclusion criteria. We found that venoarterial-extracorporeal membrane oxygenation (VA-ECMO) may have little to no positive effect on short-term survival, but the evidence was very uncertain. Impella use probably increases short-term survival (moderate certainty of evidence), whereas the timing of intra-aortic balloon pump (IABP) insertion improves outcomes (very low certainty of evidence). Pre- and post-PCI MCS implementation may result in little to no difference in bleeding complications or stroke incidence across all device types (low to very low certainty of evidence).</p><p><strong>Conclusions: </strong>Early Impella implementation before PCI may increase short-term survival, whereas the timing of ECMO or IABP implementation may have little to no effect on outcomes; however, the evidence is very uncertain.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"715-726"},"PeriodicalIF":1.1,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Circulation reportsPub Date : 2025-07-19eCollection Date: 2025-09-10DOI: 10.1253/circrep.CR-24-0184
Ayami Ogishi, Chieko Tan, Nao Saito, Koji Fukuzawa, Ikuko Miyawaki
{"title":"Self-Reported Sleep Quality and Circadian Rest-Activity Patterns in Patients With Cardiac Implantable Electronic Devices.","authors":"Ayami Ogishi, Chieko Tan, Nao Saito, Koji Fukuzawa, Ikuko Miyawaki","doi":"10.1253/circrep.CR-24-0184","DOIUrl":"10.1253/circrep.CR-24-0184","url":null,"abstract":"<p><strong>Background: </strong>Poor sleep quality is a critical concern for patients with cardiac implantable electronic devices (CIEDs). The aim of this study was to investigate the relationship between sleep quality and circadian rest-activity patterns in patients with CIEDs in Japan.</p><p><strong>Methods and results: </strong>Fifty-four patients with CIEDs were recruited. Sleep quality was assessed using the Japanese version of the Pittsburgh Sleep Quality Index, with scores ≤5 (n=19 participants) and ≥6 (n=35 participants) indicating good and poor sleep quality, respectively. Participants were instructed to wear 'Life Microscope' wristbands for 3 days at home to track their activity levels. Hourly mean values were calculated for the metabolic equivalents from the obtained activity levels, and subsequently evaluated using cosine periodic regression analysis. Parameters of circadian rest-activity patterns analyzed included mesor (mean activity), amplitude (range of activity), and acrophase time (time of peak activity). Sleep metrics, including total sleep time, sleep efficiency, and number of awakenings, were also evaluated. The Mann-Whitney U test showed that the poor sleep quality group exhibited significantly lower mesor, smaller amplitude, and later acrophase time. No other significant between-group differences were found. Furthermore, logistic regression analysis showed that acrophase time remained independently associated with self-reported sleep quality.</p><p><strong>Conclusions: </strong>Focusing on improving daily activity levels and adjusting acrophase time may be essential to improve sleep quality in patients with CIEDs.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"791-799"},"PeriodicalIF":1.1,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer Therapy-Related Cardiac Dysfunction in Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Treated With Trastuzumab and Pertuzumab.","authors":"Reina Ozaki, Ryota Morimoto, Shingo Kazama, Hiroaki Hiraiwa, Toru Kondo, Yuko Takano, Toyone Kikumori, Tomoya Shimokata, Yachiyo Kuwatsuka, Yasuko K Bando, Masahiko Ando, Yuichi Ando, Toyoaki Murohara","doi":"10.1253/circrep.CR-25-0036","DOIUrl":"10.1253/circrep.CR-25-0036","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer is the most common cancer in women. Although anti-human epidermal growth factor receptor 2 (HER2) therapy is effective in patients with HER2-positive breast cancer, it occasionally induces cancer therapy-related cardiac dysfunction (CTRCD). This study aimed to determine the factors associated with CTRCD in patients with HER2-positive breast cancer treated with trastuzumab.</p><p><strong>Methods and results: </strong>We retrospectively analyzed the data of 286 patients with breast cancer who received trastuzumab. Accordingly, patients were categorized into CTRCD (+) and CTRCD (-) groups to elucidate the factors associated with cardiotoxicity. The median age of patients was 54 years. CTRCD was observed in 13 (4.5%) patients, and 2 (0.7%) patients had severe symptomatic heart failure, with a New York Heart Association class ≥III. All patients with CTRCD had a history of epirubicin use, and patients receiving both trastuzumab and pertuzumab had significantly higher rates of CTRCD (P=0.003); the history of pertuzumab administration was an independent predictor of CTRCD development. The median duration from trastuzumab initiation to CTRCD onset and from CTRCD onset to recovery was 244 (interquartile range [IQR] 164-333) and 122 ([IQR] 38-186) days, respectively.</p><p><strong>Conclusions: </strong>In HER2-positive breast cancer, CTRCD occurred more frequently in patients using anthracycline followed by trastuzumab and pertuzumab simultaneously. Systolic dysfunction was reversible in all patients, and normalization of cardiac function took approximately 4 months from CTRCD onset.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"800-808"},"PeriodicalIF":1.1,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic Impact of Hospitalization-Associated Disability and Care Level in Older Heart Failure Patients - Findings From the J-Proof HF Registry.","authors":"Kenta Kamisaka, Masakazu Saitoh, Michitaka Kato, Kentaro Kamiya, Masanobu Taya, Tomoyuki Morisawa, Tetsuya Takahashi","doi":"10.1253/circrep.CR-25-0103","DOIUrl":"10.1253/circrep.CR-25-0103","url":null,"abstract":"<p><strong>Background: </strong>Hospitalization-associated disability (HAD) is associated with poor prognosis in patients with heart failure (HF); however, the impact of HAD in older HF patients who require long-term care remains unclear. Therefore, the aim of this study was to determine the prognostic impact of the care level and HAD onset in older HF patients.</p><p><strong>Methods and results: </strong>This study included 9,973 patients (mean age 82.6±7.7 years; 50.8% male) out of 10,062 older HF patients enrolled in a nationwide multicenter registry (Japanese Physical Therapy Multicenter Registry of Older Frail Patients With Heart Failure) for analysis. Patients were classified into 4 groups according to the level of care required under long-term care insurance (LTCI) during hospitalization. The level of care required was a risk factor for all-cause mortality and composite outcomes. In the HAD group, the adjusted hazard ratio for all-cause mortality increased with care level severity There was no interaction between the level of care required and HAD in relation to the outcomes.</p><p><strong>Conclusions: </strong>In older HF patients, both the level of care required and HAD are poor prognostic factors. In the HAD group, the level of care required is an important indicator for planning interventions to prevent poor outcomes under the LTCI system.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"809-816"},"PeriodicalIF":1.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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