T. Kurita, S. Kuramitsu, M. Ishii, A. Takasaki, T. Domei, H. Matsuo, Kazunori Horie, H. Ando, H. Terai, Y. Kikuta, Takayuki Ishihara, Tatsuya Saigusa, Tomohiro Sakamoto, N. Suematsu, Y. Shiono, Taku Asano, Kenichi Tsujita, K. Masamura, T. Doijiri, F. Toyota, M. Ogita, Jun Shiraishi, K. Harada, H. Isogai, R. Anai, Shinjo Sonoda, Hiroyoshi Yokoi, Nobuhiro Tanaka, Kaoru Dohi
{"title":"Impact of Antiplatelet Therapy on 5-Year Outcomes After Fractional Flow Reserve-Guided Deferral of Revascularization in Nonsignificant Obstructive Coronary Artery Disease","authors":"T. Kurita, S. Kuramitsu, M. Ishii, A. Takasaki, T. Domei, H. Matsuo, Kazunori Horie, H. Ando, H. Terai, Y. Kikuta, Takayuki Ishihara, Tatsuya Saigusa, Tomohiro Sakamoto, N. Suematsu, Y. Shiono, Taku Asano, Kenichi Tsujita, K. Masamura, T. Doijiri, F. Toyota, M. Ogita, Jun Shiraishi, K. Harada, H. Isogai, R. Anai, Shinjo Sonoda, Hiroyoshi Yokoi, Nobuhiro Tanaka, Kaoru Dohi","doi":"10.1253/circrep.cr-24-0069","DOIUrl":"https://doi.org/10.1253/circrep.cr-24-0069","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141820442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuke Hirao, A. Masumoto, Hiroyuki Yamamoto, Tomofumi Takaya
{"title":"Refractory Heart Failure With Reversible Left Ventricular Dysfunction and Mitral Regurgitation in Takayasu Arteritis","authors":"Yusuke Hirao, A. Masumoto, Hiroyuki Yamamoto, Tomofumi Takaya","doi":"10.1253/circrep.cr-24-0039","DOIUrl":"https://doi.org/10.1253/circrep.cr-24-0039","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141825218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Circulation reportsPub Date : 2024-07-01eCollection Date: 2024-07-10DOI: 10.1253/circrep.CR-66-0016
Masataka Sata
{"title":"Message From the Editor-in-Chief - Submission Campaign for Medical Staff.","authors":"Masataka Sata","doi":"10.1253/circrep.CR-66-0016","DOIUrl":"10.1253/circrep.CR-66-0016","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Benefit of Sacubitril/Valsartan for Hypertensive Patients in Daily Practice and Predictors of Its Antihypertensive Effect.","authors":"Takeshi Horio, Yoshio Iwashima, Minoru Yoshiyama, Daiju Fukuda, Takamasa Hasegawa, Kohei Fujimoto","doi":"10.1253/circrep.CR-24-0017","DOIUrl":"10.1253/circrep.CR-24-0017","url":null,"abstract":"<p><p><b><i>Background:</i></b> The blood pressure (BP)-lowering effect of sacubitril/valsartan (Sac/Val) is greater than that of angiotensin II receptor blockers (ARBs) but in in real-world clinical practice, Sac/Val is used in a variety of patterns other than switching from ARBs. In the present study we investigated the effects of Sac/Val on BP and biochemical parameters when switching from or adding it to various antihypertensive drugs and examined what factors could be predictors of the antihypertensive effect of Sac/Val. <b><i>Methods and Results:</i></b> In 108 hypertensive patients treated with antihypertensive agents (including 4 naïve cases), clinic BP and various biochemical parameters were assessed before and after switching to/adding Sac/Val (200 mg/day). Systolic and diastolic BPs significantly decreased after treatment with Sac/Val (P<0.0001, respectively). As for biochemical parameters, alanine aminotransferase, triglycerides, C-reactive protein, and uric acid significantly decreased after administration of Sac/Val, but renal function, B-type natriuretic peptide, and plasma renin activity (PRA) did not change before or after treatment with Sac/Val. Multiple regression analysis revealed that low PRA and high baseline systolic BP were independent determinants of systolic BP reduction after Sac/Val treatment. <b><i>Conclusions:</i></b> Sac/Val is beneficial for poorly controlled hypertension in daily clinical practice and low PRA may be a predictor of the antihypertensive effect of switching to/adding Sac/Val.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc Score for Cardiovascular Event Prediction After Bioprosthetic Valve Replacement - Subanalysis From the BPV-AF Registry.","authors":"Madoka Sano, Misa Takegami, Masashi Amano, Hidekazu Tanaka, Kenji Ando, Takeshi Kitai, Makoto Miyake, Tatsuhiko Komiya, Masaki Izumo, Hiroya Kawai, Kiyoyuki Eishi, Kiyoshi Yoshida, Takeshi Kimura, Ryuzo Nawada, Tomohiro Sakamoto, Yoshisato Shibata, Toshihiro Fukui, Kenji Minatoya, Kenichi Tsujita, Yasushi Sakata, Kumiko Sugio, Tadaaki Koyama, Tomoyuki Fujita, Kunihiro Nishimura, Chisato Izumi, Yutaka Furukawa","doi":"10.1253/circrep.CR-24-0033","DOIUrl":"10.1253/circrep.CR-24-0033","url":null,"abstract":"<p><strong>Background: </strong>There are few studies evaluating the prognostic prediction method in atrial fibrillation (AF) patients after bioprosthetic valve (BPV) replacement. The R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc score is increasingly used for the prediction of cardiovascular (CV) events in patients with AF, device implantation, and acute coronary syndrome. We aimed to evaluate the predictive value of the R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc score for future CV events in AF patients after BPV replacement.</p><p><strong>Methods and results: </strong>The BPV-AF, an observational, multicenter, prospective registry, enrolled AF patients who underwent BPV replacement. The primary outcome measure was a composite of stroke, systemic embolism, CV events including heart failure requiring hospitalization, and cardiac death. A total of 766 patients was included in the analysis. The mean R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc score was 5.7±1.8. Low (scores 0-1), moderate (scores 2-4), and high (scores 5-11) R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc score groups consisted of 12 (1.6%), 178 (23.2%), and 576 (75.2%) patients, respectively. The median follow-up period was 491 (interquartile range 393-561) days. Kaplan-Meier analysis showed a higher incidence of the composite CV events in the high R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc score group (log rank test; P<0.001). Multivariate Cox proportional hazards regression analysis revealed that the R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc score as a continuous variable was an independent predictor of composite CV outcomes (hazard ratio 1.36; 95% confidence interval 1.18-1.55; P<0.001).</p><p><strong>Conclusions: </strong>The R<sub>2</sub>-CHA<sub>2</sub>DS<sub>2</sub>-VASc score is useful for CV risk stratification in AF patients after BPV replacement.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Invasive Strategy for Octogenarians and Nonagenarians With Acute Myocardial Infarction.","authors":"Junya Komatsu, Yu-Ki Nishimura, Hiroki Sugane, Hayato Hosoda, Ryu-Ichiro Imai, Yoko Nakaoka, Koji Nishida, Shinji Mito, Shu-Ichi Seki, Toru Kubo, Hiroaki Kitaoka, Sho-Ichi Kubokawa, Kazuya Kawai, Naohisa Hamashige, Yoshinori L Doi","doi":"10.1253/circrep.CR-24-0049","DOIUrl":"10.1253/circrep.CR-24-0049","url":null,"abstract":"<p><p><b><i>Background:</i></b> Older adults with acute myocardial infarction (AMI) are currently a rapidly growing population. However, their clinical presentation and outcomes remain unresolved. <b><i>Methods and Results:</i></b> A total of 268 consecutive AMI patients were analyzed for clinical characteristics and outcomes with major adverse cardiovascular events (MACE) and all-cause mortality within 1 year. Patients aged ≥80 years (Over-80; n=100) were compared with those aged ≤79 years (Under-79; n=168). (1) Primary percutaneous coronary intervention (PCI) was frequently and similarly performed in both the Over-80 group and the Under-79 group (86% vs. 89%; P=0.52). (2) Killip class III-IV (P<0.01), in-hospital mortality (P<0.01), MACE (P=0.03) and all-cause mortality (P<0.01) were more prevalent in the Over-80 group than in the Under-79 group. (3) In the Over-80 group, frail patients showed a significantly worse clinical outcome compared with non-frail patients. (4) Multivariate analysis revealed Killip class III-IV was associated with MACE (odds ratio [OR]=3.51; P=0.02) and all-cause mortality (OR=9.49; P<0.01) in the Over-80 group. PCI was inversely associated with all-cause mortality (OR=0.13; P=0.02) in the Over-80 group. <b><i>Conclusions:</i></b> The rate of primary PCI did not decline with age. Although octogenarians/nonagenarians showed more severe clinical presentation and worse short-term outcomes compared with younger patients, particularly in those with frailty, the prognosis may be improved by early invasive strategy even in these very old patients.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: \"An Alternative Approach to Determining Metabolic Syndrome Component Cutoffs in Children and Adolescents Using Segmental Regression Analysis\".","authors":"Ayumi Miyazaki, Masao Yoshinaga, Masaki Shinomiya, Hiromitsu Ogata","doi":"10.1253/circrep.CR-24-0056","DOIUrl":"10.1253/circrep.CR-24-0056","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Circulation reportsPub Date : 2024-04-03eCollection Date: 2024-05-10DOI: 10.1253/circrep.CR-24-0022
Masato Okada, Kohei Iwasa, Koji Tanaka, Nobuaki Tanaka
{"title":"Functional Substrate of Macroreentrant Tachycardia - Similarity of the Atypical Atrial Flutter and Ventricular Tachycardia.","authors":"Masato Okada, Kohei Iwasa, Koji Tanaka, Nobuaki Tanaka","doi":"10.1253/circrep.CR-24-0022","DOIUrl":"10.1253/circrep.CR-24-0022","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11081703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CORRIGENDUM: Impact of Different Therapeutic Strategies With Left Ventricular Assist Devices on Health-Related Quality of Life During Prolonged Device-Based Support.","authors":"Mariko Asase, Takuya Watanabe, Misa Takegami, Kunihiro Nishimura, Kazuko Nin, Norihide Fukushima","doi":"10.1253/circrep.CR-66-0014","DOIUrl":"https://doi.org/10.1253/circrep.CR-66-0014","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1253/circrep.CR-22-0126.].</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10920020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140095601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}