Circulation reports最新文献

{"title":"Sustained Post-Intervention Effects of Small Community Walking on Physical Activity, Well-Being, and Social Capital Among Older Patients With Cardiovascular Disease in the Chronic Phase　- A Follow-up Multicenter Randomized Controlled Trial.","authors":"Ryo Yamashita, Shinji Sato, Yasutomo Sakai, Kotaro Tamari, Eisaku Harada, Shigeki Tsuzuku, Taishi Nakamura, Shinsuke Hanatani, Yoshinori Yamanouchi, Akira Nozuhara, Tomonori Kanazawa, Kenichi Tsujita","doi":"10.1253/circrep.CR-25-0034","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0034","url":null,"abstract":"<p><strong>Background: </strong>Because the sustained effects of physical activity (PA) and the positive psychological and social aspects during the chronic phase of cardiac rehabilitation (CR) have not been clarified, we examined the sustained post-intervention effects of small community walking (SCW) on PA, well-being, and individual-level social capital in older patients with cardiovascular disease (CVD) in the chronic phase and the influence of increased well-being and social capital on increased PA.</p><p><strong>Methods and results: </strong>The subjects were 48 older patients with CVD who were randomly divided into SCW and walking-alone groups and were available for a 6-month follow-up survey after a 3 months' intervention by healthcare workers. We measured PA, well-being (subjective happiness scale), and social capital before, 3 months after the intervention, and 6 months after the intervention ended. At 6 months post-intervention, only the SCW group maintained significant increases from the pre-intervention values in PA and well-being (P<0.01). Furthermore, increased well-being was a predictor of increased PA in the SCW group (P<0.01).</p><p><strong>Conclusions: </strong>Our results suggest that SCW effectively maintains PA and well-being, even after the intervention ends, in older patients with CVD during the chronic phase. In addition, the effects of SCW are associated with PA and well-being. The relationship between PA and individual-level social capital should be further investigated.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"877-885"},"PeriodicalIF":1.1,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Return-to-Work Outcomes and Barriers Among Patients With Cardiovascular Disease Undergoing Cardiac Rehabilitation　- A Questionnaire-Based Study.","authors":"Kei Imaoka, Junya Tanabe, Akihito Noguchi, Sho Fukuhara, Shuri Nakao, Nahoko Oya, Norimasa Egusa, Yasuo Sakai","doi":"10.1253/circrep.CR-25-0033","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0033","url":null,"abstract":"<p><strong>Background: </strong>Many patients with cardiovascular disease show no obvious physical disability after hospital discharge, making it difficult to recognize functional decline and adapt appropriate accommodations. Therefore, this study examined return-to-work (RTW) outcomes and barriers after hospital discharge.</p><p><strong>Methods and results: </strong>We conducted a questionnaire among patients aged 18-64 years who underwent inpatient cardiac rehabilitation and were discharged between January 2018 and March 2023. Of 133 eligible patients, 54 responded (response rate 41%). Respondents were classified as: (1) returned to their original job; (2) returned to a different job; and (3) did not return to any job. The overall RTW rate was 96%, with 92% returning to their original job within 3 months. However, 81% of the respondents reported anxiety, mainly about physical strain and limited workplace understanding. Physicians were the most frequently consulted professionals, while other healthcare providers were rarely sought for advice.</p><p><strong>Conclusions: </strong>Although most patients successfully returned to work, substantial anxiety persisted regarding workplace reintegration. A structured vocational support system is required, wherein healthcare providers proactively identify at-risk patients and deliver comprehensive guidance to support sustainable RTW outcomes.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"869-876"},"PeriodicalIF":1.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expectations for Robotic Support in Acute Cardiac Rehabilitation of Older Patients　- Towards a New Era.","authors":"Hidenori Kato, Tetsuya Takahashi, Naoto Kawamatsu","doi":"10.1253/circrep.CR-25-0157","DOIUrl":"10.1253/circrep.CR-25-0157","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"782-783"},"PeriodicalIF":1.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Evolocumab in Improving Low-Density Lipoprotein Cholesterol (LDL-C) Levels in a Japanese Population　- Systematic Review and Meta-Analysis.","authors":"Feng Sheng, Kazuma Miyawaki, Nobuhiro Osada, Satoru Tanaka, Zhaoyuan Liu, Toshiro Shinke","doi":"10.1253/circrep.CR-25-0109","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0109","url":null,"abstract":"<p><strong>Background: </strong>Hypercholesterolemia is a major risk factor for cardiovascular disorders. Evolocumab is efficacious and safe for the management of low-density lipoprotein cholesterol (LDL-C); however, evidence supporting the utility of evolocumab in Japanese patients is lacking. To fill this evidence gap, we conducted this systematic review and meta-analysis.</p><p><strong>Methods and results: </strong>PubMed, EMBASE, Web of Science, and the Cochrane Library from inception to October 2023 were searched for relevant publications. The primary outcomes were LDL-C levels and coronary artery plaque regression or stabilization. The secondary outcome was the incidence of adverse events. Nine studies were included: 6 randomized control trials (RCTs) and 3 cohort studies. The meta-analysis showed that evolocumab significantly reduced LDL-C levels in RCTs in the short (≤1 month), medium (≤3 months), and long (1 year) term, with a mean difference (MD) relative to placebo/standard of care (SOC) of -52.06% (95% confidence interval [CI] -59.32%, -44.79%), -69.12% (95% CI -71.45%, -66.79%), and -78.08% (95% CI -82.98%, -73.18%), respectively, and in the mid- to long (≤6 months) term in a cohort study, with an MD of -57.81% (95% CI -74.37%, -41.25%). Evolocumab also increased fibrous cap thickness and reduced macrophage grade. Adverse events were rare across included studies.</p><p><strong>Conclusions: </strong>Evolocumab seems to be effective and safe in reducing the LDL-C levels and leading to plaque regression/stabilization in Japanese patients.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"886-895"},"PeriodicalIF":1.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circadian Variability and Its Influence on Infarct Size and Clinical Outcome Among Japanese Patients With Acute Myocardial Infarction.","authors":"Tetsufumi Motokawa, Satoshi Honda, Satoshi Ikeda, Koji Maemura, Kensaku Nishihira, Misa Takegami, Sunao Kojima, Yasuhide Asaumi, Mike Saji, Jun Yamashita, Kohei Wakabayashi, Kiyoshi Hibi, Jun Takahashi, Yasuhiko Sakata, Morimasa Takayama, Tetsuya Sumiyoshi, Hisao Ogawa, Satoshi Yasuda","doi":"10.1253/circrep.CR-25-0112","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0112","url":null,"abstract":"<p><strong>Background: </strong>There is significant circadian variation in the frequency of myocardial infarction onset, with a notable increase during the early morning. However, it remains unclear whether this circadian rhythm influences post-acute myocardial infarction (AMI) clinical outcomes and infarct size.</p><p><strong>Methods and results: </strong>This study included 2,251 patients enrolled in the Japan AMI Registry (JAMIR) who had ST-elevation myocardial infarction (STEMI) with a documented time of onset, stratified into 4 time periods: 00:00-06:00, 06:00-12:00, 12:00-18:00, and 18:00-00:00 h. The primary outcome measure, used as an indicator of infarct size, was peak creatine kinase (CK) level. The median peak CK level among patients was 1,978 IU/L. No significant differences in peak CK levels were observed among the 4 time period groups (P=0.117). Similarly, the relationship between onset time and peak CK levels was not significant (P=0.215). There were no significant differences among the 4 time period groups in secondary endpoints of in-hospital mortality (P=0.788) and 1-year clinical outcomes, including all-cause mortality (P=0.544), myocardial infarction (P=0.636), stroke (P=0.943), stent thrombosis (P=0.344), and a composite endpoint (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke; P=0.430).</p><p><strong>Conclusions: </strong>Circadian variation had no effect on infarct size or clinical outcomes in patients with STEMI.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"930-938"},"PeriodicalIF":1.1,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Outcomes of Patients With Non-Valvular Atrial Fibrillation on Anticoagulants Ineligible for Phase III Trials of Direct Oral Anticoagulants　- A Retrospective Cohort Study.","authors":"Mayumi Higa, Takeshi Morimoto, Masayuki Ikeda, Shinichiro Ueda","doi":"10.1253/circrep.CR-25-0079","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0079","url":null,"abstract":"<p><strong>Background: </strong>Many patients with non-valvular atrial fibrillation (NVAF) on direct oral anticoagulants (DOACs) in real-world practice were ineligible for DOAC phase III trials. We aimed to determine the proportion of Japanese patients with NVAF eligible for these trials and compare the characteristics and outcomes of ineligible and eligible patients to determine the generalizability of the trial results.</p><p><strong>Methods and results: </strong>This retrospective cohort study included 7,826 Japanese NVAF patients on warfarin from 71 hospitals. We assessed trial eligibility and analyzed outcomes (major bleeding, stroke/systemic embolism, all-cause mortality) using Cox proportional hazards models. Nearly half (48.2%; n=3,772) of the patients were ineligible for DOAC phase III trials. Ineligible patients were older with more comorbidities and exhibited significantly higher risks of death (unadjusted hazard ratio [HR] 2.84; 95% confidence interval [CI] 2.36-3.43; P<0.0001), stroke/systemic embolism (unadjusted HR 1.53; 95% CI 1.17-1.98; P=0.0016), and major bleeding (unadjusted HR 2.00; 95% CI 1.63-2.44; P<0.0001) compared with eligible patients.</p><p><strong>Conclusions: </strong>Half of the NVAF patients receiving anticoagulant therapy in real-world practice were ineligible for phase III DOAC trials, primarily due to safety concerns. This population differs substantially from eligible patients in characteristics and outcomes. The generalizability of phase III results to real-world patients remains uncertain, warranting additional assessment.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"852-860"},"PeriodicalIF":1.1,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Serum N-Terminal Prohormone of Brain Natriuretic Peptide (NT-proBNP) Levels and Frailty in Community-Dwelling Old-Old Older Adults　- SONIC Study.","authors":"Saya Terada, Kayo Godai, Mai Kabayama, Michiko Kido, Yuya Akagi, Marlon Maus, Hiroshi Akasaka, Yoichi Takami, Takeshi Nakagawa, Saori Yasumoto, Yasuyuki Gondo, Kazunori Ikebe, Yasumichi Arai, Yukie Masui, Takumi Hirata, Koichi Yamamoto, Kei Kamide","doi":"10.1253/circrep.CR-25-0110","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0110","url":null,"abstract":"<p><strong>Background: </strong>Heart failure (HF) and frailty are increasing among aging populations, but because data on the association between potential cardiac overload or asymptomatic HF, measured by the serum level of N-terminal prohormone of brain natriuretic peptide (NT-proBNP), and frailty among community-dwelling old-old older adults (≥75 years) are limited, we examined this association.</p><p><strong>Methods and results: </strong>A cross-sectional analysis was conducted using data from a longitudinal cohort study. Frailty was assessed using the Japanese version of the Cardiovascular Health Study (J-CHS) criteria. Association between log-transformed NT-proBNP levels and frailty were examined using multinomial logistic regression. The discriminative ability of NT-proBNP for frailty was assessed using receiver operating characteristic (ROC) curve analysis. A total of 588 participants (46.9% female, median age: 77 (76-86) years) were included. Log-transformed NT-proBNP was significantly associated with frailty compared to robust (OR 1.69; 95% CI 1.23-2.32; P=0.001), even after adjusting for potential confounding factors. NT-proBNP had modest discriminative ability for frailty (AUC 0.64; 95% CI 0.59-0.70; P<0.001), with an optimal cutoff of 94.5 pg/mL.</p><p><strong>Conclusions: </strong>Elevated serum NT-proBNP levels are independently associated with frailty onset in community-dwelling old-old older adults, driven by the interaction between potential cardiac overload or asymptomatic HF and frailty. Serum NT-proBNP may be a useful tool for identifying frailty associated with cardiac overload.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"965-972"},"PeriodicalIF":1.1,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Significance of Malnutrition and Physical Function in Patients With Heart Failure.","authors":"Yoshifumi Abe, Yu Horiuchi, Mitsutoshi Akiho, Masahiko Kimura, Hideki Tanaka, Jun Tanaka, Jiro Aoki, Kengo Tanabe","doi":"10.1253/circrep.CR-24-0149","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0149","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition and impaired physical function are common comorbidities of heart failure (HF). We investigated the relationship between malnutrition and physical function, factors associated with these values, and their prognostic impact on clinical outcomes.</p><p><strong>Methods and results: </strong>We retrospectively analyzed 151 patients with HF to determine the correlation between the nutritional index, assessed using the controlling nutritional status (CONUT) score, and physical function, assessed using the short physical performance battery (SPPB). We analyzed the prognostic role of nutrition and physical function for the composite endpoints of death or HF hospitalization. The median CONUT and SPPB scores were 3 (1, 4) and 11 (8, 12), respectively. These scores showed a significant but weak correlation (r=-0.214; P=0.008). While the CONUT and SPPB scores were a significant predictor of the composite endpoint in univariable Cox analysis, only the CONUT score remained significant after adjustment for confounders. Factors associated with the CONUT score were hemoglobin and B-type natriuretic peptide levels, and those associated with the SPPB score were age, sex, and CONUT score. Using established cutoffs (i.e., CONUT ≥5, SPPB ≤9), malnutrition remained independently associated with the composite endpoint (adjusted hazard ratio 2.56; 95% confidence interval 1.46-4.48; P<0.001).</p><p><strong>Conclusions: </strong>Malnutrition and poor physical function had a weak correlation and factors associated while these values were different. Both predicted a poor prognosis and need to be assessed in patients with HF.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"904-912"},"PeriodicalIF":1.1,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Z-Score to Predict Pulmonary-Systemic Flow Ratio in Children With Atrial Septal Defect.","authors":"Naofumi F Sumitomo, Kazuki Kodo, Jun Maeda, Masaru Miura, Hiroyuki Yamagishi","doi":"10.1253/circrep.CR-25-0119","DOIUrl":"https://doi.org/10.1253/circrep.CR-25-0119","url":null,"abstract":"<p><strong>Background: </strong>The correlation between pulmonary-to-systemic flow ratio (Qp/Qs) and right heart enlargement in children with atrial septal defect (ASD) remains unclear. This study aimed to (1) assess echocardiographic Z-scores of the right heart, and (2) determine whether they predict Qp/Qs.</p><p><strong>Methods and results: </strong>This retrospective study included 175 children (median age 6.8 years; 68 males) with isolated ASD who underwent cardiac catheterization between 2013 and 2020 at 2 centers in Japan. Patients with genetic anomalies or other conditions affecting right heart size were excluded. Echocardiographic parameters were measured, converted to a Z-score, and compared with the catheterization data. In all patients, the Qp/Qs on cardiac catheterization (cQp/Qs) significantly correlated with the Z-scores of the right ventricular end-diastolic diameter of the basal (RVB), mid-cavity (RVM), and longitudinal length (RVL; r=0.54, 0.57, and 0.52, respectively). The average of these 3 parameters (ARV) showed the strongest correlation (r=0.63). Z-scores of the right atrium, tricuspid valve, and pulmonary artery showed weaker correlations. An ARV cut-off of +2.0 best predicted cQp/Qs ≥1.5 (area under the curve 0.85; 95% confidence interval 0.79-0.92; sensitivity 76.8%; specificity 82.4%). Regression-predicted cQp/Qs also significantly correlated with measured cQp/Qs (r=0.63).</p><p><strong>Conclusions: </strong>ARV may be a useful, non-invasive marker for assessing cQp/Qs and determining the indication for closure in children with ASD.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 10","pages":"956-964"},"PeriodicalIF":1.1,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Impact of Point-of-Care Ultrasound in Patients With Suspected Cardiogenic Shock　- A Systematic Review.","authors":"Takumi Osawa, Naoki Nakayama, Tomoko Ishizu, Toru Kondo, Takahiro Nakashima, Takeshi Yamamoto, Hiroyuki Hanada, Katsutaka Hashiba, Jin Kirigaya, Yumiko Hosoya, Aya Katasako-Yabumoto, Yusuke Okazaki, Masahiro Yamamoto, Kazuo Sakamoto, Marina Arai, Akihito Tanaka, Kunihiro Matsuo, Junichi Yamaguchi, Toshiaki Mano, Sunao Kojima, Teruo Noguchi, Yasushi Tsujimoto, Migaku Kikuchi, Toshikazu Funazaki, Yoshio Tahara, Hiroshi Nonogi, Tetsuya Matoba","doi":"10.1253/circrep.CR-25-0108","DOIUrl":"10.1253/circrep.CR-25-0108","url":null,"abstract":"<p><strong>Background: </strong>Cardiogenic shock, a life-threatening condition frequently encountered in emergency departments, requires rapid diagnosis and management. Point-of-care ultrasound (POCUS) is widely used as a bedside tool; however, its impact on prognosis in patients with suspected cardiogenic shock remains unclear. This systematic review aimed to evaluate whether POCUS improves the clinical outcomes in these patients.</p><p><strong>Methods and results: </strong>We searched PubMed, Web of Science, and Cochrane Library up to December 31, 2023, for studies evaluating the prognostic impact of POCUS in adults with undifferentiated shock, including cardiogenic shock. From 3,759 identified records, 2 studies (1 randomized controlled trial [RCT] and 1 observational study) involving 5,711 patients with shock were included. The RCT showed no significant differences in in-hospital mortality between the POCUS and non-POCUS groups (relative risk [RR] 0.99 [95% confidence interval (CI) 0.64-1.51]). The observational study reported higher mortality in patients receiving POCUS before intervention (RR 1.25 [95% CI 1.12-1.39]). Overall, POCUS did not significantly reduce mortality in patients with suspected cardiogenic shock. Given the limited number and quality of available studies, the certainty of evidence was low (RCT) and very low (observational study).</p><p><strong>Conclusions: </strong>Although POCUS plays an essential role in diagnosis and clinical decision-making, our review suggests that it may not significantly improve prognosis in patients with suspected cardiogenic shock. Further studies are required to determine its prognostic value.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 9","pages":"735-741"},"PeriodicalIF":1.1,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}