Circulation reports最新文献_第2页

Incidental Cardiac Uptake Leading to Early Diagnosis of Hereditary Transthyretin Amyloidosis. 偶然心脏摄取导致遗传性甲状腺转蛋白淀粉样变的早期诊断。

Circulation reports Pub Date : 2025-05-25 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0055

Masahiro Biyajima, Jun Tsuyuzaki, Takayuki Eizawa, Yoshiki Sekijima

引用次数: 0

Assessment of Cognitive Function via Biomarkers in Japanese Patients With Chronic Heart Failure Treated With Angiotensin-Receptor-Neprilysin Inhibitor. 通过生物标志物评估日本慢性心力衰竭患者接受血管紧张素受体-奈普利素抑制剂治疗的认知功能

Circulation reports Pub Date : 2025-05-24 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-24-0175

Masaya Kogure, Fukiko Kitani-Morii, Tomoya Kitani, Masatsugu Oishi, Hirokazu Shiraishi, Harutsugu Tatebe, Satoaki Matoba, Takahiko Tokuda, Takashi Kasai

{"title":"Assessment of Cognitive Function via Biomarkers in Japanese Patients With Chronic Heart Failure Treated With Angiotensin-Receptor-Neprilysin Inhibitor.","authors":"Masaya Kogure, Fukiko Kitani-Morii, Tomoya Kitani, Masatsugu Oishi, Hirokazu Shiraishi, Harutsugu Tatebe, Satoaki Matoba, Takahiko Tokuda, Takashi Kasai","doi":"10.1253/circrep.CR-24-0175","DOIUrl":"10.1253/circrep.CR-24-0175","url":null,"abstract":"Background: Angiotensin-receptor-neprilysin inhibitors (ARNIs) improve outcomes in patients with chronic heart failure (CHF). However, neprilysin is a major amyloid beta (Aβ)-degrading enzyme in the brain and although previous studies suggest that ARNI use does not induce neurocognitive dysfunction in CHF patients, data in Japanese patients are limited.Methods and results: This single-center, prospective, observational study enrolled 15 CHF patients: 6 who were being treated with ARNI (ARNI) and 9 who were not (non-ARNI). Cognitive assessments and blood biomarkers were evaluated at baseline and 1-year follow-up. Participants from the Parkinson's and Alzheimer's Disease Dimensional Neuroimaging Initiative cohort, comprising 7 patients with cerebral Aβ deposition (Aβ-positive) and 7 patients without deposition (Aβ-negative), were used for comparison. Despite the small sample size, significant differences in the Japanese version of Montreal Cognitive Assessment score and tau phosphorylated at threonine 181 level were observed between the Aβ-negative and Aβ-positive groups. In contrast, no significant difference in cognitive function or blood biomarkers were found between the non-ARNI and ARNI groups at baseline or after 1 year of follow-up.Conclusions: In this pilot-scale study, ARNI use was not associated with cognitive impairment or elevated blood biomarkers related to cognitive dysfunction in Japanese patients with CHF. Due to the limited sample size and follow-up, further validation in larger, long-term trials is warranted.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"535-541"},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12242193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occupational Therapy for Patients With Cardiovascular Disease　- A Systematic Review. 心血管疾病患者的职业治疗-系统综述。

Circulation reports Pub Date : 2025-05-21 eCollection Date: 2025-06-10 DOI: 10.1253/circrep.CR-24-0162

Tomonori Takeda, Daichi Tsukakoshi, Atsuhiro Tsubaki, Shuhei Yamamoto

{"title":"Occupational Therapy for Patients With Cardiovascular Disease　- A Systematic Review.","authors":"Tomonori Takeda, Daichi Tsukakoshi, Atsuhiro Tsubaki, Shuhei Yamamoto","doi":"10.1253/circrep.CR-24-0162","DOIUrl":"10.1253/circrep.CR-24-0162","url":null,"abstract":"Background: The prevalence of cardiovascular diseases (CVD) is high worldwide. Occupational therapy (OT) allows individuals to participate in activities of daily living (ADLs) and improves their quality of life. However, whether OT improves health-related quality of life (HRQOL), ADLs, fatigue, occupational performance, rehospitalization, and mortality in patients with CVD remains unclear. This study aimed to determine whether OT improves HRQOL, ADLs, fatigue, occupational performance, rehospitalization, and mortality in patients with CVD using a systematic review and meta-analysis.Methods and results: A literature search of 3 databases in October 2024 yielded 4 RCTs on OT in CVD patients. Two trials (n=208) assessed HRQOL, while 2 others (n=220) examined ADLs. One trial (n=23) evaluated fatigue and occupational performance, and another (n=93) assessed rehospitalization and mortality. Due to insufficient data on HRQOL and ADL improvement in 1 trial, a meta-analysis was not feasible. Similarly, a meta-analysis of fatigue, occupational performance, rehospitalization, and mortality could not be performed due to the limited number of studies.Conclusions: The results showed no clear evidence that OT improves HRQOL or ADLs in patients with CVD.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 6","pages":"395-402"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regional Disparities in Atrial Fibrillation Catheter Ablation Based on the Japanese National Survey. 基于日本全国调查的房颤导管消融的地区差异。

Circulation reports Pub Date : 2025-05-17 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0025

Takahiro Kamihara, Shinji Kaneko, Takuya Omura, Akihiro Hirashiki, Manabu Kokubo, Atsuya Shimizu

{"title":"Regional Disparities in Atrial Fibrillation Catheter Ablation Based on the Japanese National Survey.","authors":"Takahiro Kamihara, Shinji Kaneko, Takuya Omura, Akihiro Hirashiki, Manabu Kokubo, Atsuya Shimizu","doi":"10.1253/circrep.CR-25-0025","DOIUrl":"10.1253/circrep.CR-25-0025","url":null,"abstract":"Background: The prevalence of atrial fibrillation (AF) has increased with aging populations, making catheter ablation essential. However, access to this treatment across regions, even with universal healthcare, is not well understood. This study aims to explore potential regional disparities in AF catheter ablation rates and identify associated factors.Methods and results: This cross-sectional study analyzed data from the Vital Statistics survey of Japanese events in 2022 (124,947,000 people), the Japanese government Survey of Household Economy, the Survey on the Impact of the Diagnosis Procedure Combination System, and publicly available data from the Japan Heart Rhythm Society. Principal component regression analysis revealed that the number of AF hospitalizations exhibited a positive correlation with the prevalence of hypertension and the percentage of unemployed men. The number of ablations positively correlated with overtime hours, university graduate salaries, part-time employment rates, and the number of arrhythmia specialists. AF hospitalization rates exhibited a negative correlation with AF ablation rates. The number of arrhythmia specialists correlated positively with ablation rates but negatively with AF hospitalization rates.Conclusions: Socioeconomic factors appear to influence AF hospitalizations and treatment decisions. An increase in arrhythmia specialists may optimize ablation rates and reduce AF hospitalization rates.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"512-520"},"PeriodicalIF":0.0,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between the Change in Post-Cardiovascular Surgery Patients' 6-min Walking Distance and Physical Activity During Hospitalization. 心血管术后患者住院期间6分钟步行距离变化与身体活动的关系

Circulation reports Pub Date : 2025-05-17 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-24-0133

Masashi Wakana, Kiyokazu Koga, Satoshi Ohtsubo, Masaru Yoshikai, Cen Chen, Takafumi Saito, Hiro Kishimoto

{"title":"Relationship Between the Change in Post-Cardiovascular Surgery Patients' 6-min Walking Distance and Physical Activity During Hospitalization.","authors":"Masashi Wakana, Kiyokazu Koga, Satoshi Ohtsubo, Masaru Yoshikai, Cen Chen, Takafumi Saito, Hiro Kishimoto","doi":"10.1253/circrep.CR-24-0133","DOIUrl":"10.1253/circrep.CR-24-0133","url":null,"abstract":"Background: The 6-min walking distance (6MWD) is an indicator of exercise tolerance in post-cardiovascular surgery patients and is associated with life expectancy. The association between the physical activity levels of these patients during hospitalization and changes in their 6MWD and the association by activity types are unknown. We investigated the association between 6MWD changes and physical activity by activity types in post-cardiovascular surgery patients.Methods and results: Patients who had undergone cardiovascular surgery (n=70) were divided into 6MWD≥0 and 6MWD<0 groups based on the difference between their pre-surgery and pre-discharge 6MWD values. The physical activity of each patient after transfer from the intensive care unit (ICU) to the general ward was objectively measured with a triaxial accelerometer. Activity types were classified as locomotive and non-locomotive, with intensity divided into light-intensity physical activity (LPA) and moderate-to-vigorous physical activity (MVPA). The 6MWD≥0 group was significantly younger and had earlier days of ADL independence than 6MWD<0 group. In the first post-ICU discharge week, the 6MWD≥0 group engaged in significantly higher locomotive MVPA, and significantly higher non-locomotive LPA and MVPA in the following week, compared with the 6MWD<0 group.Conclusions: Among post-cardiovascular surgery patients, physical activity was higher in those with an increase in 6MWD at discharge compared with pre-surgery levels. Notably, locomotive activity was higher in the first week after ICU discharge, while non-locomotive activity increased from the second week.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"521-527"},"PeriodicalIF":0.0,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Profile and Prognosis of Patients With Acute Decompensated Heart Failure Who Met the Obesity-Related Eligibility for Subcutaneous Semaglutide　- Findings From the CURE-HF Registry. 符合肥胖相关条件的急性失代偿性心力衰竭患者的临床概况和预后——来自CURE-HF登记的发现

Circulation reports Pub Date : 2025-05-16 eCollection Date: 2025-06-10 DOI: 10.1253/circrep.CR-25-0041

Ken Nishikawa, Masatoshi Minamisawa, Koji Yoshie, Sho Suzuki, Kiu Tanaka, Yukari Okuma, Kazuhiro Kimura, Yasushi Ueki, Yasutaka Oguchi, Tamon Kato, Tatsuya Saigusa, Soichiro Ebisawa, Ayako Okada, Hirohiko Motoki, Koichiro Kuwahara

{"title":"Clinical Profile and Prognosis of Patients With Acute Decompensated Heart Failure Who Met the Obesity-Related Eligibility for Subcutaneous Semaglutide　- Findings From the CURE-HF Registry.","authors":"Ken Nishikawa, Masatoshi Minamisawa, Koji Yoshie, Sho Suzuki, Kiu Tanaka, Yukari Okuma, Kazuhiro Kimura, Yasushi Ueki, Yasutaka Oguchi, Tamon Kato, Tatsuya Saigusa, Soichiro Ebisawa, Ayako Okada, Hirohiko Motoki, Koichiro Kuwahara","doi":"10.1253/circrep.CR-25-0041","DOIUrl":"10.1253/circrep.CR-25-0041","url":null,"abstract":"Background: Obesity is well-established risk factor of heart failure (HF); however, \"obesity paradox\" has been described in symptomatic HF patients. The STEP-HFpEF study suggested that once-weekly subcutaneous semaglutide might improve outcomes in patients with obesity-related HF. We explored the prevalence of obesity-related eligibility for semaglutide treatment among patients with acute decompensated heart failure (ADHF) and evaluated their prognoses.Methods and results: We analyzed data from 1,017 ADHF patients (median, 81 years; 44.2% female) enrolled in the CURE-HF registry. We assessed prevalence of obesity-related eligibility for semaglutide administration and examined the association between this eligibility and all-cause death over a median follow-up of 2.7 years. There were 73 patients (7.2%) who were semaglutide-eligible and they had a higher proportion of diabetes mellitus than patients who were semaglutide non-eligible (64.4% vs. 26.4%, P<0.001). Kaplan-Meier analysis indicated that semaglutide-eligible patients had a significantly lower all-cause mortality rate than non-eligible patients (log-rank P=0.005). After adjustment for demographic characteristics, there was no significant difference in mortality rate between the 2 groups (adjusted hazard ratio 0.63, 95% confidence interval (CI) 0.34-1.17, P=0.14). In the propensity score-matched cohort, we did not observe a significant difference in mortality rate (log-rank, P=0.79).Conclusions: Almost 7.2% of the ADHF patients were semaglutide-eligible. Our findings did not affirm the \"obesity paradox\" in semaglutide-eligible HF patients after adjusting for demographic factors.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 6","pages":"463-472"},"PeriodicalIF":0.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of the Presence of Other People on Performing Rescue Actions in Emergency Situations　- A Questionnaire Survey. 他人在场对紧急情况下救援行动的影响-问卷调查。

Circulation reports Pub Date : 2025-05-14 eCollection Date: 2025-06-10 DOI: 10.1253/circrep.CR-24-0166

Haruka Shida, Chika Nishiyama, Satoe Okabayashi, Yosuke Yamamoto, Tomonari Shimamoto, Takashi Kawamura, Tetsuya Sakamoto, Taku Iwami

{"title":"Influence of the Presence of Other People on Performing Rescue Actions in Emergency Situations　- A Questionnaire Survey.","authors":"Haruka Shida, Chika Nishiyama, Satoe Okabayashi, Yosuke Yamamoto, Tomonari Shimamoto, Takashi Kawamura, Tetsuya Sakamoto, Taku Iwami","doi":"10.1253/circrep.CR-24-0166","DOIUrl":"10.1253/circrep.CR-24-0166","url":null,"abstract":"Background: Because bystander performance of cardiopulmonary resuscitation in out-of-hospital cardiac arrest cases is influenced by the number of rescuers/bystanders, we assessed the relationship between the presence of other people and performance of rescue actions in an actual emergency situation.Methods and results: A cross-sectional study was performed using data from an anonymous self-administered questionnaire-based survey that included laypersons who had encountered emergency situations during the past 5 years. Based on their responses related to the presence of other people, laypersons were divided into 2 groups: \"single-bystander\" (absence of others) and \"multiple-bystanders\" (presence of others). The primary outcome was any rescue action(s) performed by laypersons during an emergency. A total of 1,219 laypersons were eligible for our analysis; 69 (5.7%) encountered emergencies in which others were absent (single-bystander group) and 1,150 (94.3%) encountered emergencies in which others were present (multiple-bystanders group). The proportion of laypersons who performed any rescue actions was 95.7% in the single-bystander group and 73.8% in the multiple-bystanders group.Conclusions: The proportion of laypersons who performed any rescue actions was lower when other people were present compared with when they were absent.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 6","pages":"419-425"},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rationale and Protocol of the Registry for Contemporary Medical Management of Chronic Heart Failure With Mildly Reduced and Preserved Ejection Fraction　- The PARACLETE Study. 慢性心力衰竭伴射血分数轻度降低和保留的当代医学管理登记的基本原理和方案- PARACLETE研究

Circulation reports Pub Date : 2025-05-14 eCollection Date: 2025-06-10 DOI: 10.1253/circrep.CR-24-0138

Tomoya Ueda, Koichiro Kuwahara, Shinya Hiramitsu, Katsuya Onishi, Dai Yumino, Ayako Seno, Kenji Shiino, Maki Nogi, Masahiro Isogawa, Atsuhiko Kawamoto, Masato Kasahara, Shungo Hikoso, Yoshihiko Saito

{"title":"Rationale and Protocol of the Registry for Contemporary Medical Management of Chronic Heart Failure With Mildly Reduced and Preserved Ejection Fraction　- The PARACLETE Study.","authors":"Tomoya Ueda, Koichiro Kuwahara, Shinya Hiramitsu, Katsuya Onishi, Dai Yumino, Ayako Seno, Kenji Shiino, Maki Nogi, Masahiro Isogawa, Atsuhiko Kawamoto, Masato Kasahara, Shungo Hikoso, Yoshihiko Saito","doi":"10.1253/circrep.CR-24-0138","DOIUrl":"10.1253/circrep.CR-24-0138","url":null,"abstract":"Background: There is recent evidence for the medical treatment of heart failure (HF) with mildly reduced ejection fraction (EF) and preserved EF (HFmrEF/HFpEF). However, in real-world settings, information on how cardiologists treat patients with HFmrEF/HFpEF, especially those with chronic, mild, and stable HF or newly diagnosed HF, is lacking. In other words, we do not know when cardiologists should start and intensify medical treatment, which drugs they should choose, or why. To answer these questions, we will conduct an observational study of HFmrEF/HFpEF. Here, we describe the rationale and protocol of this observational study.Methods and results: This study will explore the therapeutic status of approximately 4,200 patients who were diagnosed or newly diagnosed with chronic HFmrEF/HFpEF (LVEF >40%) at approximately 70 cardiology clinics and hospitals. After enrolment, physicians will check whether the current medical therapy is appropriate for each patient and initiate or intensify HF medical therapy appropriately. The primary endpoints will be: (1) the proportion of patients within the categories of reasons for changing prescriptions at visit 1 of HF medical therapy and (2) a composite of unexpected HF hospitalization and all-cause death in a 2-year follow-up.Conclusions: This registry will uniquely confirm the current treatment status of patients with HFmrEF/HFpEF in real-world settings.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 6","pages":"491-496"},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Health-Related Quality of Life and Frailty in Older Patients Participating in Early Phase II Cardiac Rehabilitation. 参与早期二期心脏康复的老年患者健康相关生活质量与衰弱的关系

Circulation reports Pub Date : 2025-05-13 eCollection Date: 2025-06-10 DOI: 10.1253/circrep.CR-24-0180

Jianying Xu, Miho Nishitani-Yokoyama, Hiroki Kasuya, Mayumi Yamashita, Yusei Sato, Junya Nishimura, Mai Iida, Kei Fujiwara, Mitsuhiro Kunimoto, Yurina Sugita-Yamaguchi, Taisuke Nakade, Minoru Tabata, Kazunori Shimada, Hiroyuki Daida, Tohru Minamino

{"title":"The Relationship Between Health-Related Quality of Life and Frailty in Older Patients Participating in Early Phase II Cardiac Rehabilitation.","authors":"Jianying Xu, Miho Nishitani-Yokoyama, Hiroki Kasuya, Mayumi Yamashita, Yusei Sato, Junya Nishimura, Mai Iida, Kei Fujiwara, Mitsuhiro Kunimoto, Yurina Sugita-Yamaguchi, Taisuke Nakade, Minoru Tabata, Kazunori Shimada, Hiroyuki Daida, Tohru Minamino","doi":"10.1253/circrep.CR-24-0180","DOIUrl":"10.1253/circrep.CR-24-0180","url":null,"abstract":"Background: Frailty is a significant prognostic risk factor for cardiovascular disease and it can lead to poor quality of life due to malnutrition, fatigue, and reduced physical activity. However, few studies have investigated how frailty affects older patients participating in cardiac rehabilitation (CR) on health-related quality of life (HRQoL).Methods and results: Between November 2015 and December 2016 at Juntendo University Hospital, 217 patients (mean age 74.6±5.8 years; males 67%) participated in CR. Patients completed self-evaluations using the 36-item Short Form Survey (SF-36) and the Kihon Checklist (KCL) at the baseline of CR. The patients were divided into 3 groups: frailty group (n=81; 37%); pre-frailty group (n=71; 33%); and non-frailty group (n=65; 30%). Based on the KCL findings, we compared demographics, clinical measures, and SF-36 scores among the 3 groups. Sex, body mass index, 6-min walking distance, hemoglobin level, and low-density lipoprotein cholesterol differed significantly among the 3 groups. All SF-36 items also showed significant group differences; the frailty group scored lower than the other 2 groups on the physical component summary and mental component summary (MCS). Furthermore, the frailty group had a lower MCS score than the average Japanese age level.Conclusions: Frail older patients undergoing CR experience significant deterioration in both physical and mental dimensions of HRQoL.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 6","pages":"411-418"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low Arterial Stiffness by Pulse Wave Analysis and Aortic Diseases. 脉搏波分析与主动脉疾病的低动脉硬度分析。

Circulation reports Pub Date : 2025-04-29 eCollection Date: 2025-06-10 DOI: 10.1253/circrep.CR-25-0043

Akira Sakamoto, Yutaka Nakamura, Nobuyuki Kagiyama, Eiichiro Sato, Wataru Fujita, Tomohiro Kaneko, Tohru Minamino

{"title":"Low Arterial Stiffness by Pulse Wave Analysis and Aortic Diseases.","authors":"Akira Sakamoto, Yutaka Nakamura, Nobuyuki Kagiyama, Eiichiro Sato, Wataru Fujita, Tomohiro Kaneko, Tohru Minamino","doi":"10.1253/circrep.CR-25-0043","DOIUrl":"10.1253/circrep.CR-25-0043","url":null,"abstract":"Background: The cardio-ankle vascular index (CAVI) is an important marker of arterial stiffness, providing a blood pressure-independent assessment of vascular function. However, the clinical significance of low CAVI values remains unclear. Some connective tissue diseases are associated with aortic diseases due to intrinsic arterial wall abnormalities and may exhibit low CAVI values. This study aimed to investigate whether low CAVI is associated with these connective tissue diseases and succeeding aortic diseases.Methods and results: This was a single-center, retrospective observational study conducted at Juntendo University Hospital. A total of 17,364 patients aged 20-80 years who underwent arterial stiffness analysis using CAVI were included. Low CAVI was defined as the lowest 2.5 percentile within each sex- and age-specific distribution. The prevalences of aortic diseases (dissection and/or aneurysm) and Marfan syndrome were similar between the between the low CAVI and normal CAVI groups (aortic disease, 3.99% vs. 3.99%, P>0.99; Marfan syndrome, 0.04% vs. 0.07%, P>0.99, for the low and normal CAVI group, respectively).Conclusions: This study found no evidence that patients with low CAVI had an increased prevalence of aortic dissection, aortic aneurysm, or Marfan syndrome. Further studies are needed to clarify the clinical implications of low CAVI in vascular diseases.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 6","pages":"481-485"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0