Circulation reports最新文献

Long-Term Outcomes Following Percutaneous Coronary Intervention With Rotational Atherectomy for Severely Calcified Lesions. 经皮冠状动脉介入治疗合并动脉粥样硬化旋转切除术治疗严重钙化病变的远期疗效。

Circulation reports Pub Date : 2025-06-17 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0061

Mikako Kise, Takayuki Ishihara, Naoko Higashino, Takuya Tsujimura, Yosuke Hata, Sho Nakao, Masaya Kusuda, Toshiaki Mano

{"title":"Long-Term Outcomes Following Percutaneous Coronary Intervention With Rotational Atherectomy for Severely Calcified Lesions.","authors":"Mikako Kise, Takayuki Ishihara, Naoko Higashino, Takuya Tsujimura, Yosuke Hata, Sho Nakao, Masaya Kusuda, Toshiaki Mano","doi":"10.1253/circrep.CR-25-0061","DOIUrl":"10.1253/circrep.CR-25-0061","url":null,"abstract":"Background: While severe calcification is associated with unfavorable clinical outcomes, rotational atherectomy (RA) has been used for lesion modification of severely calcified lesions. However, long-term outcomes after percutaneous coronary intervention (PCI) with RA have not yet been fully investigated.Methods and results: We enrolled 301 patients with 334 lesions, which were treated using PCI with RA. The primary outcome was target vessel failure (TVF) defined as a composite of cardiac death (CD), target vessel myocardial infarction (MI), and target vessel revascularization (TVR). The secondary outcome was a major adverse cardiac event (MACE), defined as a composite of CD, MI, TVR, and definite stent thrombosis (ST). In addition, the predictors of TVF were evaluated using Cox proportional hazards regression analysis. The mean follow-up duration was 36.6±27.0 months. The cumulative incidence rates of TVF were 20.6%, 29.1%, and 32.5% at 2, 4, and 6 years, respectively. The 6-year cumulative incidence of MACE was 32.9%. The independent predictors of TVF were hemodialysis (hazard ratio 3.22 [95% confidential interval 1.91-5.43]) and diabetes (2.10 [1.24-3.57]).Conclusions: The 6-year TVF rate after RA reached over 30%. Hemodialysis and diabetes significantly impacted the long-term outcome. The strategy of PCI with RA should be carefully selected for severely calcified lesions in patients with hemodialysis and diabetes.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"528-534"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing Effects of Tafamidis in Controlling Left Ventricular and Left Atrial Strains in Patients With Wild-Type Transthyretin Amyloid Cardiomyopathy. 他法非地对野生型转甲状腺蛋白淀粉样心肌病患者左室和左房负荷的控制效果比较。

Circulation reports Pub Date : 2025-06-14 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0066

Chisa Eguchi, Hiroaki Kawano, Rosy Haruna Nishizawa, Tsuyoshi Yoshimuta, Chikara Ohno, Sanae Kojima, Takako Minami, Daisuke Sato, Masamichi Eguchi, Shinji Okano, Satoshi Ikeda, Mitsuharu Ueda, Koji Maemura

{"title":"Comparing Effects of Tafamidis in Controlling Left Ventricular and Left Atrial Strains in Patients With Wild-Type Transthyretin Amyloid Cardiomyopathy.","authors":"Chisa Eguchi, Hiroaki Kawano, Rosy Haruna Nishizawa, Tsuyoshi Yoshimuta, Chikara Ohno, Sanae Kojima, Takako Minami, Daisuke Sato, Masamichi Eguchi, Shinji Okano, Satoshi Ikeda, Mitsuharu Ueda, Koji Maemura","doi":"10.1253/circrep.CR-25-0066","DOIUrl":"10.1253/circrep.CR-25-0066","url":null,"abstract":"Background: Although tafamidis is used to treat patients with transthyretin amyloid cardiomyopathy (ATTR-CM), its specific effects on cardiac function remain unclear. Thus, this study aimed to investigate the effect of tafamidis on left atrial (LA) and left ventricular (LV) functions using speckle-tracking echocardiography after 1.5 years of treatment in patients with wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM).Methods and results: We included 27 patients (mean age, 76 years) with ATTRwt-CM confirmed by biopsy. We analyzed LV and LA strains using 2-dimensional speckle-tracking echocardiography and compared these parameters before and after a 1.5-year follow up between 20 patients with and 7 patients without tafamidis treatment. Echocardiography speckle tracking examination showed no significant changes in global longitudinal strain (GLS) or LA reservoir strain (LASr) in patients with ATTRwt-CM after 1.5 years of tafamidis treatment. However, significant deterioration of GLS (-9.3 [-11, -7.4] to -8.0 [-9, -6.7]; P=0.0381) and LASr (11 [6, 16] to 6 [5, 11]; P=0.0074) were observed in patients with ATTRwt-CM without tafamidis.Conclusions: The LA and LV functions of patients with ATTRwt-CM treated with tafamidis were more favorable than those of untreated patients.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"562-567"},"PeriodicalIF":0.0,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Extracorporeal Cardiopulmonary Resuscitation and Prognosis in the Short and Long Term in Patients With Acute Myocardial Infarction Complicated by Refractory Cardiac Arrest. 急性心肌梗死合并难治性心脏骤停患者体外心肺复苏与短期和长期预后的关系。

Circulation reports Pub Date : 2025-06-11 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0071

Shumpei Kosugi, Yasunori Ueda, Kuniyasu Ikeoka, Haruya Yamane, Takuya Ohashi, Takashi Iehara, Kazuho Ukai, Taro Takeuchi, Masayuki Nakamura, Tatsuhisa Ozaki, Tsuyoshi Mishima, Haruhiko Abe, Koichi Inoue, Yasushi Matsumura

{"title":"Association Between Extracorporeal Cardiopulmonary Resuscitation and Prognosis in the Short and Long Term in Patients With Acute Myocardial Infarction Complicated by Refractory Cardiac Arrest.","authors":"Shumpei Kosugi, Yasunori Ueda, Kuniyasu Ikeoka, Haruya Yamane, Takuya Ohashi, Takashi Iehara, Kazuho Ukai, Taro Takeuchi, Masayuki Nakamura, Tatsuhisa Ozaki, Tsuyoshi Mishima, Haruhiko Abe, Koichi Inoue, Yasushi Matsumura","doi":"10.1253/circrep.CR-25-0071","DOIUrl":"10.1253/circrep.CR-25-0071","url":null,"abstract":"Background: Although extracorporeal cardiopulmonary resuscitation (ECPR) is expected to improve outcomes in patients with cardiac arrest (CA), its impact on prognosis in acute myocardial infarction (MI) patients complicated by CA remains unclear. This study aimed to investigate the short- and long-term effects of ECPR on prognosis in these patients.Methods and results: This single-center, retrospective study analyzed consecutive MI patients. Patients were classified into 3 groups: CA requiring ECPR (ECPR group); CA achieving return of spontaneous circulation without ECPR (CCPR group); and without CA (non-CA group). The primary endpoint was 30-day mortality, while long-term all-cause mortality, cardiovascular death, and major adverse cardiovascular events were evaluated among discharged patients. Of the 625 patients analyzed, 57 were in the ECPR group, 104 in the CCPR group, and 464 in the non-CA group. Multivariable analysis revealed that the ECPR group had a significantly higher prevalence of 30-day mortality than the CCPR group (adjusted hazard ratio [HR] 3.99; 95% confidence interval [CI] 2.23-7.13) and the non-CA group (HR 43.48; 95% CI 19.70-95.92). However, there were no significant differences in long-term outcomes among the 3 groups.Conclusions: The 30-day mortality was worse in the ECPR group than in the CCPR or non-CA groups. In contrast, the long-term prognosis was comparable among discharged patients, regardless of the presence of CA or the need for ECPR.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"554-561"},"PeriodicalIF":0.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Further Development of Cardiovascular Intensive Care Rehabilitation　- The Required Role of Nurses in Cardiovascular Intensive Care Rehabilitation. 心血管重症康复的进一步发展——护士在心血管重症康复中的作用。

Circulation reports Pub Date : 2025-06-06 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0068

Yuya Tamaki, Kazuki Gushiken, Terumi Hirata, Yoshito Arasaki, Morikuni Wakugawa, Shuichiro Ikemiya, Haruno Nagata

引用次数: 0

Advancing Scientific Cardiac Rehabilitation　- Retrospect and Prospect. 推进心脏康复科学——回顾与展望。

Circulation reports Pub Date : 2025-06-04 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0065

Yoichi Goto

{"title":"Advancing Scientific Cardiac Rehabilitation　- Retrospect and Prospect.","authors":"Yoichi Goto","doi":"10.1253/circrep.CR-25-0065","DOIUrl":"10.1253/circrep.CR-25-0065","url":null,"abstract":"On the 30th anniversary of the founding of the Japanese Association of Cardiac Rehabilitation in 1995, this article provides an overview of the past and future of cardiac rehabilitation (CR) as science. The development of CR thus far has undoubtedly been supported not only by clinical needs but also by numerous pieces of scientific evidence regarding its effectiveness. In the first part of this article, I aim to scrutinize past evidence on CR scientifically, because all evidence must be critically examined. In the latter part, I will look ahead to the future of CR. Recently, there has been a rapid increase in very elderly frail patients with multiple comorbidities. In the near future, treatment for these patients will not be completed with acute-phase interventions targeting a single organ, and hence, patient outcome goals are expected to shift from improving survival prognosis to improving physical activity capacity and quality of life, indicating a growing need for CR like never before. Given the current rise in patients in the area where evidence is lacking, a new evidence-based CR that is not simply an extension of traditional practices is required. Taking into account the changes in the times, we must steadfastly pursue scientific CR by creating new evidence.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"500-507"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of Cardiovascular Prognostic Value of Endothelial Function Tests by Repeated Measurements. 通过重复测量内皮功能试验提高心血管预后价值。

Circulation reports Pub Date : 2025-06-03 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0042

Nobuyuki Masaki, Yuko Higashimura, Bonpei Takase

{"title":"Improvement of Cardiovascular Prognostic Value of Endothelial Function Tests by Repeated Measurements.","authors":"Nobuyuki Masaki, Yuko Higashimura, Bonpei Takase","doi":"10.1253/circrep.CR-25-0042","DOIUrl":"10.1253/circrep.CR-25-0042","url":null,"abstract":"Background: The clinical significance of monitoring endothelial function in predicting cardiovascular events has not yet been fully explored.Methods and results: Patients with diabetes or hypertension were enrolled in this study. Three flow-mediated dilation (FMD) and 2 EndoPAT reactive hyperemia index (RHI) were measured periodically in 3 years at 1.5-year intervals. Patients were followed up for 10 years after the examination period. In the FMD study, 136 patients were classified as those with consistently good endothelial function, as defined by FMD >7% on 3 occasions (n=33), and those without (n=103). In multivariate Cox analysis, patients who maintained high FMD had less thromboembolic major cardiovascular events or angina pectoris (n=24; hazard ratio [HR] 0.216; 95% confidence interval [CI] 0.047-0.985; P=0.048). In the EndoPAT study, 120 patients were classified as those with consistently abnormal endothelial function, as defined by RHI <1.67 on 2 occasions (n=34), and those without (n=86). There were 9 all-cause deaths and 10 hospitalizations for heart failure. Patients with consistent RHI <1.67 had a higher mortality (HR 10.794; 95% CI 1.520-76.629; P=0.017) and incidence of heart failure (HR 5.356; 95% CI 1.301-22.052; P=0.020).Conclusions: Repeated measurements improved the predictive performance and revealed differences between FMD and EndoPAT RHI, which were better at predicting coronary events and heart failure, respectively.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"568-577"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation for the Diagnostic Use of the HEART Score in Patients With Acute Chest Pain in Japan. 日本急性胸痛患者心脏评分诊断应用的验证

Circulation reports Pub Date : 2025-06-03 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0060

Shinnosuke Nomura, Mamoru Toyofuku, Junichi Tazaki, Shojiro Tatsushima, Takanari Fujita, Shuhei Tsuji, Takahiro Iseda, Tomoya Kimura, Yuichiro Shibamori, Yuta Matsui, Kohei Ueda, Tomohiro Ichiyanagi, Akinori Yoshida, Ryo Sakamoto, Ryotaro Kai, Takeshi Morimoto, Takeshi Kimura

{"title":"Validation for the Diagnostic Use of the HEART Score in Patients With Acute Chest Pain in Japan.","authors":"Shinnosuke Nomura, Mamoru Toyofuku, Junichi Tazaki, Shojiro Tatsushima, Takanari Fujita, Shuhei Tsuji, Takahiro Iseda, Tomoya Kimura, Yuichiro Shibamori, Yuta Matsui, Kohei Ueda, Tomohiro Ichiyanagi, Akinori Yoshida, Ryo Sakamoto, Ryotaro Kai, Takeshi Morimoto, Takeshi Kimura","doi":"10.1253/circrep.CR-25-0060","DOIUrl":"10.1253/circrep.CR-25-0060","url":null,"abstract":"Background: Current clinical guidelines recommend that patients with acute chest pain and suspected acute coronary syndrome (ACS) should be assessed using a risk scoring system. The History, Electrocardiogram, Age, Risk factors and Troponin (HEART) score is one such scoring system; however, large-scale validation studies remain limited in Japan.Methods and results: This study analyzed 487 patients presenting with chest pain in our emergency department (ED) between April and December 2022. We enrolled patients with suspected ACS without ST-segment elevation and shock state. The primary outcome was major adverse cardiovascular events (MACE) within 30 days following the ED visit. The endpoint occurred in 108 patients, including 90 patients with myocardial infarction. The HEART score identified 140 (28%) low-risk patients with a HEART score ≤3 who did not have any endpoint occurrence within 30 days. The area under the curve (AUC) values of the HEART score for MACE was 0.87. The results were more favorable when the highest troponin level was considered in calculating the conventional HEART score.Conclusions: The HEART score was reliable for predicting MACE within 30 days in patients presenting to the ED with chest pain in this single center study in Japan. Low-risk patients with HEART scores ≤3 can be safely ruled out for ACS. Considering the highest troponin level for scoring improved its diagnostic utility.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"547-553"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rolling Thrombus Within an Incompletely Closed Left Atrial Appendage. 不完全闭合左心耳内滚动血栓。

Circulation reports Pub Date : 2025-05-28 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0059

Hirokazu Tanaka, Masato Okada, Toshinari Onishi, Katsuomi Iwakura, Masaharu Ishihara

引用次数: 0

Influence of Kinesiophobia on Rehabilitation Outcomes in Patients With Cardiovascular Disease　- Protocol for Systematic Review. 运动恐惧症对心血管疾病患者康复结果的影响——系统评价方案

Circulation reports Pub Date : 2025-05-28 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0038

Yuki Nonaka, Ren Fujii, Yusuke Kawamura, Takaki Tateishi, Kazuyuki Tabira

{"title":"Influence of Kinesiophobia on Rehabilitation Outcomes in Patients With Cardiovascular Disease　- Protocol for Systematic Review.","authors":"Yuki Nonaka, Ren Fujii, Yusuke Kawamura, Takaki Tateishi, Kazuyuki Tabira","doi":"10.1253/circrep.CR-25-0038","DOIUrl":"10.1253/circrep.CR-25-0038","url":null,"abstract":"Background: Recent studies indicate a high prevalence of kinesiophobia among patients with cardiovascular disease (CVD). However, there remains a lack of consensus regarding the impact of kinesiophobia on rehabilitation outcomes. The objective of this study is to provide a comprehensive summary and synthesis of the extant evidence regarding the impact of kinesiophobia on rehabilitation outcomes in patients with CVD.Methods and results: This systematic review will adhere to the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. This systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 8 February, 2025 (Registration no. CRD42025623535). Electronic searches will be performed in the following databases: MEDLINE, PubMed, Web of Science, PsycINFO, and CINAHL electronic databases, with a date range from the start date to January 2025. The study designs were observational, encompassing cohort, case-control, or cross-sectional studies. Narrative reviews, editorials, clinical guidelines and conference abstracts will be excluded. We will consider articles that are published in English. In addition, only officially published papers are included and grey literature is excluded from the review. The specific outcomes of interest include physical function, activities of daily living, physical activity, and quality of life.Conclusions: This systematic review will provide comprehensive evidence on the relationship between kinesiophobia and rehabilitation outcomes in patients with CVD.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"7 7","pages":"578-581"},"PeriodicalIF":0.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12242194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Recurrent Heart Failure Hospitalization on Decline in Activities of Daily Living for Patients With Heart Failure and Preserved or Mildly Reduced Ejection Fraction. 反复心力衰竭住院治疗对心力衰竭患者日常生活活动能力下降的影响，并保留或轻度降低射血分数。

Circulation reports Pub Date : 2025-05-27 eCollection Date: 2025-07-10 DOI: 10.1253/circrep.CR-25-0056

Yuta Ozaki, Yusuke Uemura, Shogo Yamaguchi, Takashi Okajima, Takayuki Mitsuda, Shinji Ishikawa, Kenji Takemoto, Toyoaki Murohara, Masato Watarai

引用次数: 0