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Impact of Nutritional Status and Cardiopulmonary Exercise Testing-Based Exercise Education on Long-Term Outcomes in Acute Coronary Syndrome - Insights From the Mie ACS Registry. 营养状况和基于心肺运动试验的运动教育对急性冠脉综合征长期预后的影响——来自Mie ACS登记处的见解
Circulation reports Pub Date : 2024-11-09 eCollection Date: 2024-12-10 DOI: 10.1253/circrep.CR-24-0128
Hiroaki Murakami, Naoki Fujimoto, Keishi Moriwaki, Hiromasa Ito, Akihiro Takasaki, Kiyotaka Watanabe, Atsushi Kambara, Naoto Kumagai, Takashi Omura, Tairo Kurita, Ryo Momosaki, Kaoru Dohi
{"title":"Impact of Nutritional Status and Cardiopulmonary Exercise Testing-Based Exercise Education on Long-Term Outcomes in Acute Coronary Syndrome - Insights From the Mie ACS Registry.","authors":"Hiroaki Murakami, Naoki Fujimoto, Keishi Moriwaki, Hiromasa Ito, Akihiro Takasaki, Kiyotaka Watanabe, Atsushi Kambara, Naoto Kumagai, Takashi Omura, Tairo Kurita, Ryo Momosaki, Kaoru Dohi","doi":"10.1253/circrep.CR-24-0128","DOIUrl":"10.1253/circrep.CR-24-0128","url":null,"abstract":"<p><strong>Background: </strong>Exercise training based on cardiopulmonary exercise testing (CPET) improves outcomes in patients with acute coronary syndrome (ACS), while nutritional status is also crucial. This study evaluated CPET implementation and the impacts of clinical parameters, including CPET and nutritional status, on 2-year outcomes in ACS patients.</p><p><strong>Methods and results: </strong>Data from 2,621 ACS patients enrolled in the Mie ACS registry were analyzed. Of these, 938 were hospitalized in CPET-equipped facilities, while 1,683 were not. Nutritional status was assessed using controlling nutritional status (CONUT) score. Cox regression analysis evaluated the associations between nutritional status, CPET-based exercise education, and 2-year prognosis. Among the 938 patients in CPET facilities, 359 underwent CPET and received exercise education. During the 2-year follow up, 60 all-cause deaths occurred. Univariate Cox regression revealed that CPET implementation was associated with lower all-cause mortality. Other predictors included hemoglobin levels, age, hospitalization length, Killip class ≥2, mechanical support, and malnutrition. In multivariate Cox regression, CPET implementation remained an independent predictor of mortality (hazard ratio 0.47; P=0.04). However, when nutritional status was included, moderate to severe malnutrition emerged as an independent predictor of all-cause mortality (hazard ratio 2.47; P=0.02), diminishing the significance of CPET (P=0.058).</p><p><strong>Conclusions: </strong>Moderate to severe malnutrition is a powerful independent prognostic factor for mortality in the Mie ACS registry. CPET implementation may enhance survival in ACS patients.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 12","pages":"583-591"},"PeriodicalIF":0.0,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Controlling Serum Low-Density Lipoprotein Cholesterol and Triglycerides on Long-Term Clinical Outcomes in Diabetic Patients Who Have Undergone Percutaneous Coronary Intervention. 控制血清低密度脂蛋白胆固醇和甘油三酯对经皮冠状动脉介入治疗的糖尿病患者长期临床结果的影响
Circulation reports Pub Date : 2024-11-07 eCollection Date: 2024-12-10 DOI: 10.1253/circrep.CR-24-0081
Takashi Maruo, Amane Ike, Yosuke Takamiya, Yuta Matsuoka, Eiji Shigemoto, Yuta Kato, Takashi Kuwano, Makoto Sugihara, Akira Kawamura, Shin-Ichiro Miura
{"title":"Impact of Controlling Serum Low-Density Lipoprotein Cholesterol and Triglycerides on Long-Term Clinical Outcomes in Diabetic Patients Who Have Undergone Percutaneous Coronary Intervention.","authors":"Takashi Maruo, Amane Ike, Yosuke Takamiya, Yuta Matsuoka, Eiji Shigemoto, Yuta Kato, Takashi Kuwano, Makoto Sugihara, Akira Kawamura, Shin-Ichiro Miura","doi":"10.1253/circrep.CR-24-0081","DOIUrl":"10.1253/circrep.CR-24-0081","url":null,"abstract":"<p><strong>Background: </strong>We investigated whether patients with diabetes who had good control of both low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) would be associated with better long-term clinical outcomes after percutaneous coronary intervention (PCI).</p><p><strong>Methods and results: </strong>Using our PCI registry (Fu-Registry), the 1,006 cases with diabetes were divided into 4 groups: Group 1, LDL-C ≥100 mg/dL and TG ≥175 mg/dL; Group 2, LDL-C <100 mg/dL and TG ≥175 mg/dL; Group 3, LDL-C ≥100 mg/dL and TG <175 mg/dL; and Group 4, LDL-C <100 mg/dL and TG <175 mg/dL. The primary endpoint during the follow-up period (median follow up of 1,984 days) was defined as major adverse cardiac events (MACEs). Additionally, all coronary events were defined as a secondary endpoint. The incidence rates of MACEs were as follows: Group 1, 38%; Group 2, 26%; Group 3, 31%; and Group 4, 27% (P=0.074), and the rates tended to be higher in Group 1. All coronary events were as follows: Group 1, 66%; Group 2, 56%; Group 3, 58%; and Group 4, 51% (P=0.032).</p><p><strong>Conclusions: </strong>In patients with diabetes who underwent PCI, the LDL-C and TG levels in Group 4 met secondary prevention targets for coronary artery disease and these patients showed better long-term clinical outcomes compared with those in other groups.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 12","pages":"573-582"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of Neovascularization in Achilles Tendon Xanthoma With Familial Hypercholesterolemia. 家族性高胆固醇血症并发跟腱黄色瘤新生血管的检测。
Circulation reports Pub Date : 2024-11-07 eCollection Date: 2024-12-10 DOI: 10.1253/circrep.CR-24-0120
Junji Mochizuki, Yoko Koike, Hiroaki Matsumi, Kentaro Kawada, Yoshiki Hata
{"title":"Detection of Neovascularization in Achilles Tendon Xanthoma With Familial Hypercholesterolemia.","authors":"Junji Mochizuki, Yoko Koike, Hiroaki Matsumi, Kentaro Kawada, Yoshiki Hata","doi":"10.1253/circrep.CR-24-0120","DOIUrl":"10.1253/circrep.CR-24-0120","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 12","pages":"602-603"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial Lesion and Diastolic Dysfunction May Be Associated With Atrial Fibrillation in Patients With Cardiac Amyloidosis. 心房病变和舒张功能障碍可能与心脏淀粉样变性患者的心房颤动有关。
Circulation reports Pub Date : 2024-11-06 eCollection Date: 2024-12-10 DOI: 10.1253/circrep.CR-24-0116
Kaishi Otsuka, Hiroaki Kawano, Hirofumi Koike, Eijun Sueyoshi, Shuji Arakawa, Satoki Fukae, Asumi Takei, Tsuyoshi Yoshimuta, Satoshi Ikeda, Koji Maemura
{"title":"Atrial Lesion and Diastolic Dysfunction May Be Associated With Atrial Fibrillation in Patients With Cardiac Amyloidosis.","authors":"Kaishi Otsuka, Hiroaki Kawano, Hirofumi Koike, Eijun Sueyoshi, Shuji Arakawa, Satoki Fukae, Asumi Takei, Tsuyoshi Yoshimuta, Satoshi Ikeda, Koji Maemura","doi":"10.1253/circrep.CR-24-0116","DOIUrl":"10.1253/circrep.CR-24-0116","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) is a common arrhythmia associated with cardiac amyloidosis (CA). Diastolic dysfunction and atrial lesions have been reported in patients with AF fibrillation. We aimed to evaluate the diastolic function and atrial lesions in patients with CA and AF.</p><p><strong>Methods and results: </strong>We included 27 patients (mean age 72 years) with biopsy-confirmed CA. We analyzed the average E/e' as diastolic function using echocardiography and atrial late gadolinium enhancement (LGE) as an atrial lesion using cardiac magnetic resonance imaging (CMRI). We compared these parameters among 20 patients with sinus rhythm (SR) and 7 with AF. Echocardiography examination showed that average E/e' were larger in the AF group than in the SR group (average E/e': AF, 21.3 [14.5-30.3]; SR, 14.2 [10.3-16.9]; P=0.0053). CMRI demonstrated that atrial LGE was more severe in the AF group than in the SR group (AF, 7/7 [100%]; SR, 11/21 [52.4%]; P=0.00228). Univariate logistic regression analysis showed that average E/e' demonstrated significant association with AF in all patients (odds ratio 1.24; [95% confidence interval 1.03-1.51]; P=0.0251).</p><p><strong>Conclusions: </strong>AF may be associated with atrial lesions and diastolic dysfunction in patients with CA.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 12","pages":"539-546"},"PeriodicalIF":0.0,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Limb Ischemia Due to Paradoxical Thrombus Through Patent Foramen Ovale. 经卵圆孔未闭的异位血栓引起的急性肢体缺血。
Circulation reports Pub Date : 2024-10-29 eCollection Date: 2024-12-10 DOI: 10.1253/circrep.CR-24-0117
Tomohiro Honda, Hiroaki Kawano, Ryosuke Iwasaki, Yuki Ueno, Ryohei Akashi, Tsuyoshi Yonekura, Tsuyoshi Yoshimuta, Koji Maemura
{"title":"Acute Limb Ischemia Due to Paradoxical Thrombus Through Patent Foramen Ovale.","authors":"Tomohiro Honda, Hiroaki Kawano, Ryosuke Iwasaki, Yuki Ueno, Ryohei Akashi, Tsuyoshi Yonekura, Tsuyoshi Yoshimuta, Koji Maemura","doi":"10.1253/circrep.CR-24-0117","DOIUrl":"10.1253/circrep.CR-24-0117","url":null,"abstract":"","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 12","pages":"598-599"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142809035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence (AI)-Driven Frailty Prediction Using Electronic Health Records in Hospitalized Patients With Cardiovascular Disease. 使用电子健康记录对心血管疾病住院患者进行人工智能(AI)驱动的虚弱预测。
Circulation reports Pub Date : 2024-10-29 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0112
Masashi Yamashita, Kentaro Kamiya, Kazuki Hotta, Anna Kubota, Kenji Sato, Emi Maekawa, Hiroaki Miyata, Junya Ako
{"title":"Artificial Intelligence (AI)-Driven Frailty Prediction Using Electronic Health Records in Hospitalized Patients With Cardiovascular Disease.","authors":"Masashi Yamashita, Kentaro Kamiya, Kazuki Hotta, Anna Kubota, Kenji Sato, Emi Maekawa, Hiroaki Miyata, Junya Ako","doi":"10.1253/circrep.CR-24-0112","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0112","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to create a deep learning model for predicting phenotypic physical frailty from electronic medical record information in patients with cardiovascular disease.</p><p><strong>Methods and results: </strong>This single-center retrospective study enrolled patients who could be assessed for physical frailty according to cardiovascular health study criteria (25.5% [691/2,705] of the patients were frail). Patients were randomly separated for training (Train set: 80%) and validation (Test set: 20%) of the deep learning model. Multiple models were created using LightGBM, random forest, and logistic regression for deep learning, and their predictive abilities were compared. The LightGBM model had the highest accuracy (in a Test set: F1 score 0.561; accuracy 0.726; area under the curve of the receiver operating characteristics [AUC] 0.804). These results using only commonly used blood biochemistry test indices (in a Test set: F1 score 0.551; accuracy 0.721; AUC 0.793) were similar. The created models were consistently and strongly associated with physical functions at hospital discharge, all-cause death, and heart failure-related readmission.</p><p><strong>Conclusions: </strong>Deep learning models derived from large sample sizes of phenotypic physical frailty have shown good accuracy and consistent associations with prognosis and physical functions.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"495-504"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Older Patients With Cardiogenic Shock Using the Impella Device - Insights From the Japanese Registry for Percutaneous Ventricular Assist Device (J-PVAD). 使用 Impella 装置的老年心源性休克患者的预后--日本经皮心室辅助装置注册中心 (J-PVAD) 的启示。
Circulation reports Pub Date : 2024-10-29 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0111
Ryosuke Higuchi, Mamoru Nanasato, Yumiko Hosoya, Mitsuaki Isobe
{"title":"Outcomes of Older Patients With Cardiogenic Shock Using the Impella Device - Insights From the Japanese Registry for Percutaneous Ventricular Assist Device (J-PVAD).","authors":"Ryosuke Higuchi, Mamoru Nanasato, Yumiko Hosoya, Mitsuaki Isobe","doi":"10.1253/circrep.CR-24-0111","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0111","url":null,"abstract":"<p><strong>Background: </strong>Aging has progressed in several regions of the world with more older patients experiencing acute cardiovascular disease. Impella is a percutaneous potent circulatory support device associated with substantial cost and potential device-related complications.</p><p><strong>Methods and results: </strong>We analyzed the Japanese nationwide registry, encompassing consecutive patients with cardiogenic shock using Impella. Among 5,718 patients treated between 2020 and 2022, we compared older patients (≥75 years) with younger patients. The primary outcome was the Kaplan-Meier estimated 30-day mortality, and the secondary outcome was Impella-related complications. The median age of the 5,718 patients was 69 (58-77) years, and 1,807 (31.6%) were older, with smaller body mass index, frequent acute coronary syndrome, and infrequent myocarditis. Comorbidities were frequently observed in older patients with a higher ejection fraction and less frequency of extracorporeal membrane oxygenation. Older patients had a higher 30-day mortality than younger patients (38.9% vs. 32.5%; P<0.0001). The 30-day mortality was statistically equivalent among older subsets (75-79 vs. 80-84 vs. ≥85 years). Device-related complications similarly occurred similarly among the older subsets, except for a modest increase in cardiac tamponade and limb ischemia. Older age, body mass index, myocarditis, prior arrhythmia, shock severity, renal and hepatic impairment, and limb ischemia were associated with 30-day mortality.</p><p><strong>Conclusions: </strong>The selected older patients using Impella exhibited modestly higher 30-day mortality with similar safety profiles. A longer follow up and optimal patient selection are important.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"505-513"},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Task Shifting in Cardiac Catheterization to Sustain Physicians and Acute Coronary Syndrome Response Centers - Findings From the 2024 Japanese Circulation Society Chugoku-Shikoku Regional Survey. 心导管插入术的任务转移,以维持医生和急性冠状动脉综合征反应中心——来自2024年日本循环学会Chugoku-Shikoku地区调查的结果
Circulation reports Pub Date : 2024-10-26 eCollection Date: 2024-12-10 DOI: 10.1253/circrep.CR-24-0100
Takeshi Suetomi, Noriko Fukue, Mari Ishida, Makiko Taniyama, Natsuko Mukai-Yatagai, Takahiro Sakamoto, Tomoko Tamada, Tomomi Matsuura, Kazuaki Tanabe, Yukiko Nakano
{"title":"Task Shifting in Cardiac Catheterization to Sustain Physicians and Acute Coronary Syndrome Response Centers - Findings From the 2024 Japanese Circulation Society Chugoku-Shikoku Regional Survey.","authors":"Takeshi Suetomi, Noriko Fukue, Mari Ishida, Makiko Taniyama, Natsuko Mukai-Yatagai, Takahiro Sakamoto, Tomoko Tamada, Tomomi Matsuura, Kazuaki Tanabe, Yukiko Nakano","doi":"10.1253/circrep.CR-24-0100","DOIUrl":"10.1253/circrep.CR-24-0100","url":null,"abstract":"<p><strong>Background: </strong>Sustainability of the 24/7 acute coronary syndrome response system is at risk due to the Work Style Reform for physicians.</p><p><strong>Methods and results: </strong>A survey of 93 facilities in Chugoku-Shikoku region found that 30% of facilities expected acute coronary syndrome services to be restricted due to the Work Style Reform. Approximately 35% had implemented task shifting, which reduced physicians' workload by 30% and improved team care.</p><p><strong>Conclusions: </strong>Task shifting improved the working environment. However, various barriers to implementation were also identified. Further investigation is needed to achieve a balance between the Work Style Reform and sustainability of the acute coronary syndrome response system.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 12","pages":"592-597"},"PeriodicalIF":0.0,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioprosthetic Valve Positions in Patients With Atrial Fibrillation - Insights From the BPV-AF Registry. 心房颤动患者的生物人工瓣膜位置--来自 BPV-AF 登记的启示。
Circulation reports Pub Date : 2024-10-19 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0110
Yuki Obayashi, Makoto Miyake, Misa Takegami, Masashi Amano, Takeshi Kitai, Tomoyuki Fujita, Tadaaki Koyama, Hidekazu Tanaka, Kenji Ando, Tatsuhiko Komiya, Masaki Izumo, Hiroya Kawai, Kiyoyuki Eishi, Kiyoshi Yoshida, Takeshi Kimura, Ryuzo Nawada, Tomohiro Sakamoto, Yoshisato Shibata, Toshihiro Fukui, Kenji Minatoya, Kenichi Tsujita, Yasushi Sakata, Masayuki Fukuzawa, Kyokun Uehara, Toshihiro Tamura, Kunihiro Nishimura, Yutaka Furukawa, Chisato Izumi
{"title":"Bioprosthetic Valve Positions in Patients With Atrial Fibrillation - Insights From the BPV-AF Registry.","authors":"Yuki Obayashi, Makoto Miyake, Misa Takegami, Masashi Amano, Takeshi Kitai, Tomoyuki Fujita, Tadaaki Koyama, Hidekazu Tanaka, Kenji Ando, Tatsuhiko Komiya, Masaki Izumo, Hiroya Kawai, Kiyoyuki Eishi, Kiyoshi Yoshida, Takeshi Kimura, Ryuzo Nawada, Tomohiro Sakamoto, Yoshisato Shibata, Toshihiro Fukui, Kenji Minatoya, Kenichi Tsujita, Yasushi Sakata, Masayuki Fukuzawa, Kyokun Uehara, Toshihiro Tamura, Kunihiro Nishimura, Yutaka Furukawa, Chisato Izumi","doi":"10.1253/circrep.CR-24-0110","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0110","url":null,"abstract":"<p><strong>Background: </strong>Data on the impact of valve position on clinical outcomes in patients with atrial fibrillation (AF) and bioprosthetic valves (BPVs) are limited.</p><p><strong>Methods and results: </strong>The BPV-AF Registry was a multicenter, prospective, observational study involving 894 patients with BPVs and AF. In this post-hoc substudy, patients were classified according to BPV position: aortic (n=588; 65.8%), mitral (n=195; 21.8%), or both (n=111; 12.4%). The primary outcome was a composite of stroke/systemic embolism, major bleeding, heart failure requiring hospitalization, all-cause death, or BPV reoperation. During a mean follow up of 15.3±4.0 months, the primary outcome occurred in 90 (15.3%) patients (12.7/100 patient-years) in the aortic group, 25 (12.8%; 10.2/100 patient-years) in the mitral group, and 16 (14.4%; 11.8/100 patient-years) in the both-valves group (log-rank P=0.621). The unadjusted and adjusted risks were not significant for the mitral and both-valves groups relative to the aortic group (unadjusted hazard ratio [95% confidence interval] 0.80 [0.52-1.25] and 0.92 [0.54-1.57]; adjusted hazard ratio 0.89 [0.51-1.54] and 1.10 [0.58-2.09], respectively). There was no significant difference in the incidence of stroke/systemic embolism or major bleeding among the 3 groups (log-rank P=0.651 and 0.156, respectively).</p><p><strong>Conclusions: </strong>In patients with BPVs and AF, the risk for the composite outcome was comparable regardless of the BPV position.</p>","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"521-528"},"PeriodicalIF":0.0,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of Angiographic Deterioration Following Inframalleolar Angioplasty and Its Impact on Outcomes in Patients With Chronic Limb-Threatening Ischemia Requiring Repeat Intervention. 需要再次介入治疗的慢性肢体缺血患者接受无瓣膜血管成形术后血管造影恶化的发生率及其对疗效的影响
Circulation reports Pub Date : 2024-10-18 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0103
Yosuke Hata, Osamu Iida, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takuya Tsujimura, Yasuhiro Matsuda, Hiroyuki Uematsu, Sho Nakao, Masaya Kusuda, Wataru Ariyasu, Toshiaki Mano
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