Circulation reports最新文献_第10页

Holding Health Seminars at Acute Care Hospitals and Fitness Clubs to Prevent Heart Failure. 在急症医院和健身俱乐部举办健康讲座，预防心力衰竭。

Circulation reports Pub Date : 2024-09-28 eCollection Date: 2024-11-08 DOI: 10.1253/circrep.CR-24-0097

Yuta Nakaya, Yugo Horii, Kazuma Tanimoto

{"title":"Holding Health Seminars at Acute Care Hospitals and Fitness Clubs to Prevent Heart Failure.","authors":"Yuta Nakaya, Yugo Horii, Kazuma Tanimoto","doi":"10.1253/circrep.CR-24-0097","DOIUrl":"https://doi.org/10.1253/circrep.CR-24-0097","url":null,"abstract":"Ehime Prefecture has the highest heart failure mortality rate among men and women in Japan. Healthy life expectancy is low nationwide, which may be related to sarcopenia and frailty. Uwajima City contains a progresses aging of the population in the Ehime Prefecture. Therefore, preventing heart failure requires treatment and patient education not only for the underlying disease, but also for the complications associated with aging, such as sarcopenia and frailty. In 2020, we began working with the fitness club LocomoK.O to focus on prevention after the onset of disease and prevention before onset. We have commenced surveys of healthy older adults living in the community in Uwajima City, including the Short Physical Performance Battery, physical functions such as handgrip strength, and body composition assessment using in-body tests. The data showed that the rate of sarcopenia was extremely high, at 70% in patients with acute heart failure and 39% in the healthy older group, and that 24% of patients with acute heart failure had severe sarcopenia. Based on the collected data, we started health seminars in 2023 to educate citizens about the disease to prevent the onset and recurrence of heart disease, which is in line with the current situation in Uwajima City. We hope that our activities will help those struggling with local medical care.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 11","pages":"477-480"},"PeriodicalIF":0.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Usefulness of Native T1 in Cardiac Magnetic Resonance Imaging and Echocardiographic Strain Parameters for Detecting Early Cardiac Involvement in Fabry Cardiomyopathy. 心脏磁共振成像中的原位 T1 和超声心动图应变参数对检测法布里心肌病早期心脏受累的有用性

Circulation reports Pub Date : 2024-09-26 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0068

Shoko Nakagawa, Masashi Amano, Yurie Tamai, Ayaka Mizumoto, Shinichi Kurashima, Yuki Irie, Kenji Moriuchi, Takahiro Sakamoto, Makoto Amaki, Hideaki Kanzaki, Yoshiaki Morita, Takeshi Kitai, Chisato Izumi

{"title":"Usefulness of Native T1 in Cardiac Magnetic Resonance Imaging and Echocardiographic Strain Parameters for Detecting Early Cardiac Involvement in Fabry Cardiomyopathy.","authors":"Shoko Nakagawa, Masashi Amano, Yurie Tamai, Ayaka Mizumoto, Shinichi Kurashima, Yuki Irie, Kenji Moriuchi, Takahiro Sakamoto, Makoto Amaki, Hideaki Kanzaki, Yoshiaki Morita, Takeshi Kitai, Chisato Izumi","doi":"10.1253/circrep.CR-24-0068","DOIUrl":"10.1253/circrep.CR-24-0068","url":null,"abstract":"Background: Non-invasive diagnosis of disease stage in Fabry cardiomyopathy with multimodality imaging is pivotal when deciding on the appropriate time to initiate enzyme replacement therapy. However, this approach has not been well established.Methods and results: We enrolled 14 patients with Fabry disease. All patients were evaluated using echocardiography and contrast cardiac magnetic resonance (CMR), and were divided into either an early-stage group without left ventricular hypertrophy (LVH; wall thickness >12 mm) or late gadolinium enhancement (LGE; n=7; median age 37 years; 4 female), or an advanced-stage group with LVH and/or LGE (n=7; median age 66 years; 7 female). Strain data from echocardiography and T1 mapping on CMR were compared between the groups. In the advanced-stage group, all strain data were impaired. In the early-stage group, localized longitudinal strain in the basal posterolateral segment was already reduced but both localized and global circumferential strain remained preserved. On CMR analysis, global and localized native T1 shortening were observed in the early-stage group, but were pseudo-normalized in the advanced-stage group. In logistic regression analysis, localized circumferential strain had significant diagnostic value for differentiating between early- and advanced stage (P=0.037) and significantly improved the predictive power of the model containing localized native T1 in CMR.Conclusions: A combination of localized native T1 in CMR and echocardiographic strain parameters could be useful for staging Fabry cardiomyopathy.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"456-464"},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Inspiratory Muscle Training in Patients With Acute Decompensated Heart Failure. 吸气肌训练对急性失代偿性心力衰竭患者的疗效。

Circulation reports Pub Date : 2024-09-21 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0085

Junichi Yokota, Ren Takahashi, Keisuke Matsushima, Takeru Suzuki, Yuuko Matsukawa

{"title":"Efficacy of Inspiratory Muscle Training in Patients With Acute Decompensated Heart Failure.","authors":"Junichi Yokota, Ren Takahashi, Keisuke Matsushima, Takeru Suzuki, Yuuko Matsukawa","doi":"10.1253/circrep.CR-24-0085","DOIUrl":"10.1253/circrep.CR-24-0085","url":null,"abstract":"Background: Inspiratory muscle training (IMT) is supported for outpatients with stable chronic heart failure, but its efficacy in hospitalized patients with acute decompensated heart failure (ADHF) remains unclear. The aim of the present study was to clarify IMT efficacy and safety in hospitalized ADHF patients.Methods and results: Patients with inspiratory muscle weakness who underwent cardiac rehabilitation (CR) were analyzed. The control group was historical control data of patients admitted to the same facility. IMT was performed at 30% maximal inspiratory mouth pressure (15 reps/set, 2 sets/day, 5 times/week) with usual CR. Associations between IMT and changes in the 2-min walking distance (2MWD) were assessed using a linear mixed model. In total, 31 and 29 patients in the IMT and control groups (median age 83 [71-88] vs. 86 [77-88] years), respectively, were analyzed. After adjustment for covariates and propensity scores, calculated on the basis of heart-failure severity, frailty, physical function, nutritional status, and inspiratory muscle strength, the 2MWD was significantly higher in the IMT group than in the control group (F=4.697; P=0.035; ∆2MWD; +31.9 vs. +16.3 m). Among 348 IMT sessions, no adverse cardiovascular events or absolute termination criteria were identified. Eleven (3.2%) IMT sessions met relative termination criteria.Conclusions: Adding IMT to usual CR improves the 2MWD, can be safely performed in hospitalized patients with ADHF, and may represent a novel CR approach in patients with ADHF.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"430-440"},"PeriodicalIF":0.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Vericiguat on Left Ventricular Reverse Remodeling in Patients Who Have Heart Failure With Reduced Ejection Fraction　- Special Focus on Patients Without Quadruple Medical Therapy. 韦立克对射血分数降低型心力衰竭患者左心室逆重塑的影响--特别关注未接受四联疗法的患者。

Circulation reports Pub Date : 2024-09-21 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0076

Chihiro Fujii, Mana Hiraishi, Kentaro Yamashita, Hiroshi Tsunamoto, Wataru Fujimoto, Susumu Odajima, Ken-Ichi Hirata, Hidekazu Tanaka

{"title":"Effect of Vericiguat on Left Ventricular Reverse Remodeling in Patients Who Have Heart Failure With Reduced Ejection Fraction　- Special Focus on Patients Without Quadruple Medical Therapy.","authors":"Chihiro Fujii, Mana Hiraishi, Kentaro Yamashita, Hiroshi Tsunamoto, Wataru Fujimoto, Susumu Odajima, Ken-Ichi Hirata, Hidekazu Tanaka","doi":"10.1253/circrep.CR-24-0076","DOIUrl":"10.1253/circrep.CR-24-0076","url":null,"abstract":"Background: A novel cardioprotective drug, vericiguat, reduces the risk of cardiovascular mortality for patients already on guideline-directed medical therapy. However, the effect of vericiguat on left ventricular (LV) reverse remodeling in patients with reduced LV ejection fraction (LVEF) with or without guideline-directed medical therapy, known as quadruple medical therapy, remains undetermined.Methods and results: This study comprised 73 heart failure (HF) patients with reduced LVEF (<45%) from 5 institutions in Japan. Echocardiography was performed before and 6.1±3.9 months after administration of vericiguat. LV reverse remodeling was observed in all patients (LV end-diastolic volume 156.1±52.6 vs. 139.3±60.0 mL; P<0.001; LV end-systolic volume 108.1±41.2 vs. 91.8±51.2 mL; P<0.001; LVEF 31.8±7.4 vs. 37.6±12.3 %; P<0.001). LV reverse remodeling was also observed in 54 patients who could not undergo quadruple medical therapy for several reasons. Moreover, the incidence of cardiovascular events was also similar for patients who received or did not receive quadruple medical therapy (log-rank P=0.555).Conclusions: Significant LV reverse remodeling was observed in HF patients with reduced LVEF following administration of vericiguat. LV reverse remodeling was also observed in patients who could not receive quadruple medical therapy, thus making administration of vericiguat a potential new approach for treatment of these patients.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"448-455"},"PeriodicalIF":0.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-World Evidence of Feasible Assessment and Intervention in Cardiovascular Physical Therapy for Older Patients With Heart Failure　- Insight From the J-Proof HF of the Japanese Society of Cardiovascular Physical Therapy. 针对老年心力衰竭患者的心血管物理治疗可行评估和干预的现实世界证据--日本心血管物理治疗学会 J-Proof HF 的启示。

Circulation reports Pub Date : 2024-09-21 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0058

Yuji Kono, Koji Sakurada, Yuki Iida, Kentato Iwata, Michitaka Kato, Kentaro Kamiya, Masakazu Saitoh, Masanobu Taya, Yoshinari Funami, Tomoyuki Morisawa, Tetsuya Takahashi

{"title":"Real-World Evidence of Feasible Assessment and Intervention in Cardiovascular Physical Therapy for Older Patients With Heart Failure　- Insight From the J-Proof HF of the Japanese Society of Cardiovascular Physical Therapy.","authors":"Yuji Kono, Koji Sakurada, Yuki Iida, Kentato Iwata, Michitaka Kato, Kentaro Kamiya, Masakazu Saitoh, Masanobu Taya, Yoshinari Funami, Tomoyuki Morisawa, Tetsuya Takahashi","doi":"10.1253/circrep.CR-24-0058","DOIUrl":"10.1253/circrep.CR-24-0058","url":null,"abstract":"Background: This study aimed to clarify the feasibility of cardiovascular physical therapy assessment and intervention in older patients with heart failure (HF) in Japan.Methods and results: We performed a secondary analysis of data from a nationwide multicenter registry (the J-Proof HF), and enrolled consecutive HF patients aged ≥65 years who were prescribed cardiovascular physical therapy during hospitalization from December 2020 to March 2022. Of the 9,650 enrolled patients (median age 83.0 years; 49.8% male), the availability rate of comorbidities and assessments was >95%. In the activities of daily living (ADL) assessment, the Barthel Index (BI) and Functional Independence Measure were 97.6% and 60.4%, respectively. The results of the physical therapy assessment indicated completion rates of ≥80%, with lower rates of <60% for gait speed and short-performance physical battery in the group with a BI of <85 points. In physiotherapy intervention, gait training and muscle strength training were performed by >80% of patients, whereas aerobic exercise and resistance training were performed by 35.4% and 2.6% patients, respectively.Conclusions: Our results in this study indicated that medical findings, such as comorbidities, echocardiography, and laboratory findings, were considered a feasible assessment that could be confirmed at all hospitals. Gait training, ADL training, and muscle strength training are much more common than exercise training in older patients with HF.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"441-447"},"PeriodicalIF":0.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated B-Type Natriuretic Peptide Level as a Residual Risk Factor for Ventricular Arrhythmias Among Patients Undergoing Cardiac Resynchronization Therapy With Improved Left Ventricular Ejection Fraction. 在接受心脏再同步化疗法并改善左室射血分数的患者中，B 型钠利尿肽水平升高是室性心律失常的残留风险因素。

Circulation reports Pub Date : 2024-09-14 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0065

Junichi Kamoshida, Nobuhiko Ueda, Kohei Ishibashi, Takashi Noda, Takanori Kawabata, Satoshi Oka, Yuichiro Miyazaki, Akinori Wakamiya, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Yuko Inoue, Koji Miyamoto, Satoshi Nagase, Takeshi Aiba, Hideaki Kanzaki, Chisato Izumi, Teruo Noguchi, Kengo Kusano

{"title":"Elevated B-Type Natriuretic Peptide Level as a Residual Risk Factor for Ventricular Arrhythmias Among Patients Undergoing Cardiac Resynchronization Therapy With Improved Left Ventricular Ejection Fraction.","authors":"Junichi Kamoshida, Nobuhiko Ueda, Kohei Ishibashi, Takashi Noda, Takanori Kawabata, Satoshi Oka, Yuichiro Miyazaki, Akinori Wakamiya, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Yuko Inoue, Koji Miyamoto, Satoshi Nagase, Takeshi Aiba, Hideaki Kanzaki, Chisato Izumi, Teruo Noguchi, Kengo Kusano","doi":"10.1253/circrep.CR-24-0065","DOIUrl":"10.1253/circrep.CR-24-0065","url":null,"abstract":"Background: Patients who achieve improved left ventricular ejection fraction (LVEF >35%) with cardiac resynchronization therapy (CRT) are at a lower risk of ventricular arrhythmia (VA). Little is known about the significance of the B-type natriuretic peptide (BNP) level for the risk of VA. This study investigated the risk factors for VA in CRT and the risk stratification of VA with BNP in CRT with improved LVEF.Methods and results: This study evaluated 352 CRT patients from 2012 to 2020. Patients were categorized into 2 groups: improved LVEF (impEF; LVEF >35%), and low LVEF (lowEF; LVEF ≤35%). The serum BNP levels 6 months after CRT device implantation were measured. The primary endpoint was defined as VA requiring treatment with anti-tachycardia pacing or shock or persisting for ≥30 s. Overall, 102 patients had improved LVEF. The impEF group had a significantly lower VA risk than the lowEF group. Patients with low BNP had a lower VA risk than those with high BNP; however, no significant difference was observed between patients with high BNP and those in the lowEF group. Univariate analysis revealed that high BNP was a predictor of VA in the impEF group.Conclusions: The VA risk is reduced with improved LVEF after CRT but not with high BNP levels. The post-BNP level after CRT implantation is a useful marker for predicting VA in patients with improved LVEF.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"407-414"},"PeriodicalIF":0.0,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Intravascular Lithotripsy on an Underexpanded Stent Due to Severe Calcification. 血管内碎石术对因严重钙化而扩张不足的支架的效果。

Circulation reports Pub Date : 2024-09-13 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0096

Kensho Baba, Kensaku Nishihira, Yoshisato Shibata

引用次数: 0

Study Protocol and Mission for the Tohoku Registry of Acute Aortic Dissection (TRAD). 东北急性主动脉夹层登记处（TRAD）的研究计划和任务。

Circulation reports Pub Date : 2024-09-13 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0079

Kota Itagaki, Shintaro Katahira, Konosuke Sasaki, Midori Miyatake, Koki Ito, Kiichiro Kumagai, Norihiro Kondo, Shinya Masuda, Daichi Takagi, Azuma Tabayashi, Keisuke Kanda, Ai Ishizawa, Atsushi Yamashita, Cholsu Kim, Shunsuke Kawamoto, Masaaki Naganuma, Keiichi Ishida, Kyohei Ueno, Yoshikatsu Saiki

{"title":"Study Protocol and Mission for the Tohoku Registry of Acute Aortic Dissection (TRAD).","authors":"Kota Itagaki, Shintaro Katahira, Konosuke Sasaki, Midori Miyatake, Koki Ito, Kiichiro Kumagai, Norihiro Kondo, Shinya Masuda, Daichi Takagi, Azuma Tabayashi, Keisuke Kanda, Ai Ishizawa, Atsushi Yamashita, Cholsu Kim, Shunsuke Kawamoto, Masaaki Naganuma, Keiichi Ishida, Kyohei Ueno, Yoshikatsu Saiki","doi":"10.1253/circrep.CR-24-0079","DOIUrl":"10.1253/circrep.CR-24-0079","url":null,"abstract":"Background: Acute aortic dissection (AAD) is a life-threatening condition that imposes a significant socioeconomic burden on society. The Tohoku Registry of Acute Aortic Dissection (TRAD) is a collaboration of 13 tertiary referral hospitals in the Tohoku region of Japan designed to investigate all aspects of AAD treatment in this district, and to address significant clinical questions to help understand its dynamic pathology and develop optimal strategies for treating AAD.Methods and results: Comprehensive cases developing type A and type B AAD, including those with prehospital cardiopulmonary arrest transported to TRAD centers, over 5 years from 2017 to 2022 are registered. The TRAD dataset encompasses prehospital information, diagnostic imaging findings, treatment modalities, and outcomes for each case. After discharge, patients will be followed up for 10 years for survival, aortic events and inspection data.Conclusions: We believe that this multicenter registry of AAD analyses will clarify the current short-term outcomes of recent surgical, endovascular, and medical treatments in the Tohoku region, and provide insights into the long-term outcomes of different treatment modalities to achieve extended life expectancy in reasonably good health.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"465-468"},"PeriodicalIF":0.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case of Infective Endocarditis With Aneurysmal Perforation of Both Aortic and Mitral Valve Leaflets. 感染性心内膜炎伴主动脉瓣和二尖瓣瓣叶动脉瘤样穿孔病例

Circulation reports Pub Date : 2024-09-12 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0063

Katsuya Suzuki, Haruka Sasaki, Hiroyuki Takaoka, Kazuki Yoshida, Moe Matsumoto, Yusei Nishikawa, Shuhei Aoki, Yoshitada Noguchi, Satomi Yashima, Noriko Suzuki-Eguchi, Makiko Kinoshita, Rei Hashimoto, Jun-Ichiro Ikeda, Yoshio Kobayashi

引用次数: 0

Novel Method for Risk Stratification of Major Adverse Clinical Events Using Pre- and Post-Ablation Left Atrial Volume Index in Patients With Persistent Atrial Fibrillation. 利用持续性心房颤动患者消融前和消融后左心房容积指数对主要不良临床事件进行风险分层的新方法

Circulation reports Pub Date : 2024-09-07 eCollection Date: 2024-10-10 DOI: 10.1253/circrep.CR-24-0062

Hironori Ishiguchi, Yasuhiro Yoshiga, Akihiko Shimizu, Masakazu Fukuda, Ayumi Omuro, Masahiro Hisaoka, Yusuke Nakashima, Miho Fujita, Shintaro Hashimoto, Takuya Omuro, Toru Ariyoshi, Shigeki Kobayashi, Takayuki Okamura, Motoaki Sano

{"title":"Novel Method for Risk Stratification of Major Adverse Clinical Events Using Pre- and Post-Ablation Left Atrial Volume Index in Patients With Persistent Atrial Fibrillation.","authors":"Hironori Ishiguchi, Yasuhiro Yoshiga, Akihiko Shimizu, Masakazu Fukuda, Ayumi Omuro, Masahiro Hisaoka, Yusuke Nakashima, Miho Fujita, Shintaro Hashimoto, Takuya Omuro, Toru Ariyoshi, Shigeki Kobayashi, Takayuki Okamura, Motoaki Sano","doi":"10.1253/circrep.CR-24-0062","DOIUrl":"10.1253/circrep.CR-24-0062","url":null,"abstract":"Background: The relationship between changes in the left atrial volume index (LAVI) post-catheter ablation (CA) and long-term prognostic events in patients with persistent atrial fibrillation (AF) remains unclear. We evaluated the incidence of major adverse clinical events (MACE), including all-cause death, unplanned heart failure hospitalization, and unplanned cardiovascular hospitalization using pre- and post-CA LAVI.Methods and results: We collected data retrospectively from 150 patients with persistent AF who underwent their first CA. LAVI was calculated during preprocedural echocardiography under AF rhythm (pre-CA LAVI) and 3 months post-CA under sinus rhythm (post-CA LAVI). The cumulative incidence of MACE was compared among 3 subgroups based on the cutoff values of pre-CA (45.5 mL/m2) and post-CA (46.5 mL/m2; both determined using the c-statistic) LAVI. The subgroup of a pre-CA LAVI >45.5 mL/m2 with a post-CA LAVI >46.5 mL/m2 (n=45) had a significantly higher MACE incidence compared with other subgroups (P=0.002). Multivariate analysis identified this subgroup as independently at higher risk for MACE. The subgroup of a pre-CA LAVI >45.5 mL/m2 with a post-CA LAVI ≤46.5 mL/m2 (n=49) had an incidence comparable with those with pre-CA LAVI ≤45.5 mL/m2 (n=56) and exhibited a significantly greater reduction in LAVI than other subgroups did (P<0.001).Conclusions: Combining pre-CA and post-CA LAVIs is valuable in stratifying long-term MACE development risk following CA.","PeriodicalId":94305,"journal":{"name":"Circulation reports","volume":"6 10","pages":"415-423"},"PeriodicalIF":0.0,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11464015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0