Randomised Crossover Trial of Home-Based Neuromuscular Electrical Stimulation Therapy as an Adjunct to Cardiac Rehabilitation in Frail Older Adult Patients With Chronic Heart Failure.

Circulation reports Pub Date : 2025-03-07 eCollection Date: 2025-04-10 DOI:10.1253/circrep.CR-24-0091
Shintaro Ono, Michitaka Kato, Hiromasa Seko, Eiji Nakatani, Toshiya Omote, Mayuko Omote, Shingo Omote
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Abstract

Background: Neuromuscular electrical stimulation (NMES) is an alternative therapy for patients unable to perform sufficient voluntary exercises. This randomised crossover study aimed to evaluate the safety and efficacy of home-based NMES as an adjunct to cardiac rehabilitation (CR) for improving physical function in frail older adult patients with chronic heart failure (CHF).

Methods and results: 8 frail older adult patients with CHF underwent 8 weeks of CR supplemented with home-based NMES and 8 weeks of CR alone in random order, separated with a 4-week washout period. NMES at 50-Hz frequency was administered for 50 min/day, 5 times per week, with electrodes placed on the legs. Changes in the short physical performance battery (SPPB) score, leg strength, and the Barthel index were assessed between patients with CR with and without home-based NMES. No NMES-related adverse events were observed. CR with home-based NMES had a higher total SPPB score and 5-repetition sit-to-stand test time of 2.67 points and -10.67 s, respectively, than CR alone (95% confidence interval [CI] 0.3-5.0, P<0.05 and 95% CI -19.5 to -1.3, P<0.05, respectively). No significant leg strength or Barthel index changes were observed between CR with and without home-based NMES.

Conclusions: Home-based NMES safely improved physical function in frail older adult patients with CHF.

以家庭为基础的神经肌肉电刺激疗法辅助老年慢性心力衰竭患者心脏康复的随机交叉试验
背景:神经肌肉电刺激(NMES)是一种替代疗法,用于患者不能进行足够的自愿运动。这项随机交叉研究旨在评估以家庭为基础的NMES作为心脏康复(CR)辅助治疗改善老年慢性心力衰竭(CHF)患者身体功能的安全性和有效性。方法和结果:8例体弱的老年CHF患者随机接受了8周CR加家庭NMES和8周CR单独治疗,并有4周的洗脱期。以50 hz频率给予NMES 50分钟/天,每周5次,电极放置在腿部。评估有和没有家庭NMES的CR患者的短时间物理性能电池(SPPB)评分、腿部力量和Barthel指数的变化。未观察到nmes相关不良事件。家庭NMES联合CR的SPPB总分和5次重复坐立测试时间分别高于单独CR的2.67分和-10.67 s(95%可信区间[CI] 0.3-5.0, p)。结论:家庭NMES安全改善体弱老年CHF患者的身体功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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