{"title":"[Vaccine hesitancy and One Health : towards a more integrated approach to rethinking vaccination in public health].","authors":"Marine Paridans, Benoît Pétré","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a context characterised by the emergence and re-emergence of infectious diseases, as well as the anticipated recurrence of health crises, vaccination remains a cornerstone of preventive public health. However, its effectiveness continues to be undermined by vaccine hesitancy, a multifaceted phenomenon shaped by a wide range of determinants. This situation underscores the need to design and implement more integrated vaccination strategies that extend beyond a strictly biomedical approach. The operational principles of the One Health approach, which emphasise intersectoral and interdisciplinary collaboration, the sharing of knowledge and resources, and effective communication and information exchange, offer a particularly relevant framework for rethinking vaccination policies and addressing vaccine hesitancy. By fostering more context-sensitive, inclusive, and acceptable strategies, this approach can contribute to improving population vaccination coverage.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"288-293"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148202049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica Hendrick, Claudia Cacucci, Marie Delvenne, Bernard Duysinx, Renaud Louis, Anne Sibille
{"title":"[Lung cancer and the environment : state of the art and perspectives].","authors":"Jessica Hendrick, Claudia Cacucci, Marie Delvenne, Bernard Duysinx, Renaud Louis, Anne Sibille","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lung cancer carries a high burden owing to its high incidence and high mortality rate. The dismal prognosis of this frequent disease is mainly due to late-stage diagnosis. Tobacco-induced lung cancer accounts for an approximate 85 % of the cases, although an increasing number light or never-smokers are diagnosed with this disease, stressing the contribution of the environment to its development. Environmental risk factors have been recognized, such as residential radon, outdoor air pollution including fine particles and a range of toxic compounds used in the occupational context, in particular asbestos. The exposome integrates both environmental and individual genetic factors contributing to the risk of developing lung cancer. Its use in prevention and early intervention programs should help personalize these approaches and enhance their efficacy, potentially leading to reducing the mortality associated with this disease.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"315-320"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[One Health, three inseparable pillars : human health, animal health and environnemental health].","authors":"André Scheen, Patrizio Lancellotti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The current special issue of the Revue Médicale de Liège assembles 21 articles, which all are devoted to one of the different aspects of One Health, an emergent polymorphic concept. Taken together, these contributions illustrate the diversity of this concept that requires a coordinated interdisciplinary approach to tackle major challenges to which our modern society is confronted.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"255-256"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Climate change and global pollution : endocrine consequences].","authors":"André Scheen, Albert Beckers","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Modern industrial societies have profoundly transformed our environment. Climate change - particularly global warming - and pollution, whether atmospheric or chemical and present in water and food, exert detrimental effects on both human and animal health. In particular, alterations in endocrine function have been reported. This narrative review summarizes current knowledge on the effects of global warming and environmental pollution on the function of three glands under hypothalamic-pituitary control: the adrenal cortex, the thyroid gland, and the gonads.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"353-358"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Global warming : a cardiovascular risk factor in it's own right].","authors":"Hélène Petitjean, Cédric Davidsen, Patrizio Lancellotti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Global warming and the accompanying environmental changes now represent a major determinant of cardiovascular morbidity and mortality. Data from the Global Burden of Disease rank air pollution among the leading causes of death worldwide, with a predominance of cardiovascular events. Chronic exposure to fine particulate matter promotes the development and progression of atherosclerosis, while pollution spikes and extreme temperature variations act as triggers for acute events such as acute coronary syndrome (ACS), strokes, and arrhythmias. It is important to emphasize that 18-20 % of ACS cases occur in the absence of traditional cardiovascular risk factors, suggesting the involvement of environmental factors.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"334-341"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[«One Health», a major contemporary issue].","authors":"Gilles Darcis, Nicolas Antoine-Moussiaux","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The One Health concept embodies an integrative and systemic vision of health, recognizing the interdependence between human, animal, plant and ecosystem health. In the face of growing global challenges such as pandemics, antimicrobial resistance, and environmental degradation, this collaborative approach, particularly between medical, veterinary, ecological, and social disciplines, is a necessity. This «One Health» special issue offers a selection of articles describing a diverse approach to the ways in which this concept questions the medical field.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"258-260"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justine Laverdeur, Mutien-Marie Garigliany, Laureline Lecoq, Annick Linden, Daniel Desmecht
{"title":"[Expansion of the Asian tiger mosquito and associated arboviral diseases in Europe: effects of climate change and surveillance].","authors":"Justine Laverdeur, Mutien-Marie Garigliany, Laureline Lecoq, Annick Linden, Daniel Desmecht","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The summer of 2025 and its historic chikungunya outbreak marked a turning point in the way we approach mosquito-borne viral diseases in Europe, and in particular those which depends on Aedes albopictus, the Asian tiger mosquito, for their transmission. These arboviral infections show a pronounced dependence on global change, owing to complex interactions between very different organisms. Mosquitoes, in particular, are highly sensitive to the effects of climate change. In this context, Aedes albopictus, an invasive species showing substantial adaptability and robustness, continues to expand across Europe, notably in Northern Europe. This mosquito is a key vector, in particular for dengue and chikungunya, whose clinical presentation is often non-specific, complicating diagnosis and the early detection of clusters. Faced with these complex characteristics, the challenge is to organize integrated surveillance that combines entomological monitoring, human surveillance, and adaptation to a situation that is, by its very nature, evolving. In Belgium, entomological surveillance (MEMO+) and mandatory case notification-structured differently across the country's entities-constitute essential yet still improvable pillars of this surveillance.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"266-272"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Impact of air pollution on the respiratory system from a One Health perspective].","authors":"Jeanne Marechal, Maëlle Bosmans, Renaud Louis, Didier Cataldo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article examines, within the framework of the \"One Health\" approach, the effects of air pollution on the respiratory system. Air pollution is currently the environmental risk factor responsible for the highest rates of morbidity and mortality. Data from the literature indicate that pollution has a major impact on lung cancer, increasing its incidence as well as the risk of developing lung metastases. Pollution also contributes to the development and exacerbation of chronic obstructive pulmonary disease and asthma. Pollution is a widespread problem, and health care providers, including doctors, have an important role to play in limiting its consequences.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"321-326"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Biodiversity and pandemic risk : rethinking emerging zoonoses at the human-animal-ecosystem interface].","authors":"Pauline Van Leuwen, Johan Michaux","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pandemics do not emerge at random. They emerge in landscapes transformed by human activities, where contacts between humans, domestic animals, wildlife, and infectious agents are being reshaped. Deforestation, urbanization, agricultural intensification, land-use change, and climate change increase opportunities for spillover and redraw high-risk interfaces. Biodiversity is neither a systematic shield nor an intrinsic threat : its role depends on the structure of host communities, the species favored by disturbed environments, and the concrete conditions of exposure. Social inequalities and socio-economic vulnerability also weigh on these dynamics by limiting prevention capacities. Preventing emerging zoonoses therefore requires shifting the focus away from the pathogen alone toward the socio-ecological systems that make their emergence possible.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"261-265"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Environmental factors and tubulointerstitial nephropathy : the paradigm of «chronic interstitial nephritis in agricultural communities» (CINAC)].","authors":"François Jouret, Benjamin Vervaet, Marc De Broe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic Interstitial Nephritis in Agricultural Communities (CINAC) represents a major public health challenge, primarily affecting young to middle-aged agricultural workers. Clinically, CINAC is characterized by low-grade proteinuria, a bland urinary sediment, and rapidly progressive renal failure. Kidney biopsies disclose large dysmorphic lysosomes containing electron-dense non-membrane aggregates in proximal tubular cells. Although the disease was long attributed to recurrent episodes of dehydration, its pathophysiology is now recognized as more complex. Indeed, the heat-stress hypothesis alone does not adequately explain the heterogeneous geographic distribution of CINAC. Converging epidemiological, environmental, and toxicological evidence suggests a significant role for chronic exposure to pesticides. Several classes of agrochemicals experimentally demonstrated cumulative nephrotoxicity, involving oxidative stress, tubular apoptosis, and mitochondrial and lysosomal dysfunction. The frequent detection of pesticide residues in drinking water and soils within endemic regions indicates chronic low-dose exposure, sometimes independent of direct occupational handling. Heat stress likely acts as a cofactor, amplifying toxicity through dehydration, reduced renal perfusion, and intratubular concentration of toxins. Overall, CINAC appears to result from a multifactorial etiology dominated by exposure to agrochemical mixtures, underscoring the need for integrated and sustainable prevention strategies including depollution and/or reversed osmosis of drinkable water.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"359-364"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}