Manon Heine, Maxime Jason, Unal Duran, Frédéric Kridelka
{"title":"[Tubo-ovarian abscess fistulized to the abdominal wall, due to a Klebsiella pneumoniae infection].","authors":"Manon Heine, Maxime Jason, Unal Duran, Frédéric Kridelka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tubo-ovarian abscess (TOA) is a serious complication of pelvic inflammatory disease, most often of polymicrobial origin. It may rarely progress to complicated forms, particularly in cases of delayed diagnosis or in patients with underlying comorbidities. We report a rare complication of TOA characterized by subcutaneous abdominal wall fistulization, associated with an unusual Klebsiella pneumoniae infection. This pathogen, classically involved in urinary and gastrointestinal infections, is rarely described in TOA. Management combining drainage of the collection and prolonged targeted antibiotic therapy resulted in a favorable outcome.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"559-561"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean Perriot, François Marchandise, Gérard Peiffer
{"title":"[The role of therapeutic education in the care of tuberculosis patients].","authors":"Jean Perriot, François Marchandise, Gérard Peiffer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tuberculosis is a major cause of death worldwide. It affects mainly low- and middle-income countries, but also persists in vulnerable populations in high-income countries. How well tuberculosis treatments work depends on strict adherence, which is compromised by the length of the protocols, the adverse effects of the drugs, and unfavourable psychosocial factors. Therapeutic education aims to strengthen the self-management skills, autonomy, and quality of life of patients with tuberculosis. It applies to both latent tuberculosis infection and active tuberculosis and improves understanding of the disease, treatment adherence, management of comorbidities, and the fight against stigma. This structured, continuous, multidisciplinary, patient-centered strategy is an essential lever for optimizing treatment outcomes and strengthening the fight against tuberculosis.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"578-582"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Parinaud syndrome : a diplopia unlike any other].","authors":"Lydia Belhabib, Anne-Catherine Chapelle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sudden-onset diplopia warrants an emergency management in ophthalmology. A binocular, vertical and persistent diplopia, should raise suspicion of a central lesion, particularly within the brainstem. We reporte the case of a 53-year-old man, who presented with acute vertical binocular diplopia. Ophthalmological examination revealed a bilateral elevation limitation, characteristic of Parinaud's syndrome. Brain magnetic resonance imaging identified a right-sided ischemic midbrain infarction, and further cardiovascular work-up demonstrated a patent foramen ovale causing a right-to-left shunt.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"569-573"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pulmonary hypertension associated with interstitial lung diseases: current state of the art].","authors":"Adrien Lozina, Quentin Maloir, Gilles Parzibut, Fanny Gester, Raluca Elena Dulgheru, Hélène Petitjean, Cédric Davidsen, Patrizio Lancellotti, Céline Defourny, Colin Desir, Perrine Canivet, Renaud Louis, Julien Guiot","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pulmonary hypertension associated with interstitial lung diseases (PH-ILD) is a common and severe complication of interstitial lung diseases. Diagnosis is challenging and relies on a combination of clinical, functional, biological, radiological and echocardiographic findings. Definitive diagnosis is established by right heart catheterisation, which confirms the presence of pre-capillary pulmonary hypertension associated with increased pulmonary vascular resistance. Until 2021, and the INCREASE study, all randomised controlled trials evaluating therapies approved for pulmonary arterial hypertension in patients with PH-ILD yielded disappointing results. However, recent advances exploring the potential of novel therapeutic strategies have renewed interest in PH-ILD, with a progressive paradigm shift opening new perspectives for a condition that was until recently associated with a poor prognosis.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"589-596"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Leadless pacemakers : current evidence and future perspectives].","authors":"Hugo Dassy, Riad Tajildin, Sébastien Piron, Caroline Piette, Vincenzo Miraglia, Patrizio Lancellotti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Leadless pacemakers represent a major advance in cardiac pacing. Unlike conventional systems, they are entirely implanted within the heart, without transvenous leads or a subcutaneous generator, thereby substantially reducing the risks of infection, lead fracture, and device displacement. First introduced in 2012 with the Nanostim™ (St. Jude Medical®), this technology subsequently evolved with the market introduction of the Micra™ (Medtronic®), which is easy to implant and has a safety profile comparable to that of conventional pacemakers. More recently, the AVEIR™ system (Abbott's®) has marked a further milestone by enabling leadless dual-chamber pacing with direct «implant-to-implant» communication between the atrial and ventricular modules. This evolution paves the way for more complex leadless pacing strategies comparable to conventional systems. In addition, this latest model allows device retrieval and repositioning, overcoming some of the limitations of earlier generations.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"574-577"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149172237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marine Sluys, Alexandre Haumann, Aurélie Ladang, Patrick Pétrossians
{"title":"[Calcitonin measurement in fine needle aspiration washout fluid : when biology arbitrates between two cytological diagnoses].","authors":"Marine Sluys, Alexandre Haumann, Aurélie Ladang, Patrick Pétrossians","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Medullary thyroid carcinoma is a lesion whose preoperative diagnosis mainly relies on serum calcitonin measurement and cytology obtained by fine-needle aspiration. A marked elevation of calcitonin during the evaluation of a thyroid nodule constitutes a warning signal. The sensitivity of cytology is limited because of the tumor's morphological heterogeneity. Measurement of calcitonin in the washout fluid from the aspiration needle and syringe significantly improves diagnostic performance, both for thyroid nodules and for suspicious lymph nodes. This clinical vignette illustrates the importance of integrating biological and cytological data to optimize the initial management. It raises several questions: What is the role of serum calcitonin measurement in the evaluation of thyroid nodules? Why can cytology miss the diagnosis of medullary carcinoma? What benefits does measuring calcitonin in fine-needle aspiration washout fluid provide? Finally, how can the accuracy of the preoperative diagnosis influence the surgical strategy ?</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"609-612"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisca Isia Nanci, Ghislain Bisimwa Balakula, Gaylord Ngaboyeka Amani, Faila Juliana Luciana, François Boemer, Vincent Bours, Oreste Battisti, Richard Mbusa Kambale
{"title":"[Neonatal screening for sickle cell disease in South Kivu, eastern Democratic Republic of Congo : a hospital-based cross-sectional study].","authors":"Francisca Isia Nanci, Ghislain Bisimwa Balakula, Gaylord Ngaboyeka Amani, Faila Juliana Luciana, François Boemer, Vincent Bours, Oreste Battisti, Richard Mbusa Kambale","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Newborn screening for sickle cell disease (SCD) is a key public health intervention. Data from eastern Democratic Republic of the Congo (DRC) are limited. This study assessed the prevalence of SCD and the feasibility of screening in maternity units in South Kivu. Cord blood was analyzed by mass spectrometry. Among 1.300 newborns, 128 had sickle cell trait (9.8 %; 95 % CI: 8.2-11.5 %), and no homozygous cases. Screening is feasible at birth and findings support its integration into routine maternal and child health services.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"604-608"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amaury Masson, Orianne de la Brassinne Bonardeaux, Nils de Marneffe, Vincenzo Miraglia, Caroline Piette, Patrizio Lancellotti
{"title":"[Sudden cardiac death and hypertrophic cardiomyopathy : risk assessment and indications for implantable cardioverter-defibrillator].","authors":"Amaury Masson, Orianne de la Brassinne Bonardeaux, Nils de Marneffe, Vincenzo Miraglia, Caroline Piette, Patrizio Lancellotti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypertrophic cardiomyopathy (HCM) is a myocardial disease characterized by left ventricular hypertrophy without abnormal loading conditions. Despite significant advances in management, HCM remains a major cause of sudden cardiac death, particularly in young individuals. Prevention relies on accurate arrhythmic risk stratification and the selective implantation of implantable cardioverter-defibrillators (ICDs). This article reviews current indications for primary prevention ICD implantation in sarcomeric HCM based on the European Society of Cardiology (ESC) guidelines and compares them with the more integrative approach proposed by the American College of Cardiology/American Heart Association (ACC/AHA).</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"583-588"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Integration of clinical, biological and imaging data in medical decision-making].","authors":"Patrizio Lancellotti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This issue of the Revue Médicale de Liège brings together clinical observations, therapeutic reviews and public health studies. They share a common message: medical decision-making relies on the integration of clinical, biological and imaging data, weighed against scientific evidence and each patient's context.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"557-558"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Evolocumab (Repatha®) : new evidence across the continuum of atherosclerotic cardiovascular disease].","authors":"Patrizio Lancellotti, André Scheen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Evolocumab is a monoclonal antibody targeting PCSK9 that provides rapid and sustained LDL-cholesterol reduction. Following FOURIER, which demon-strated a reduction in cardiovascular events in patients with established atherosclerotic cardiovascular disease, VESALIUS-CV extends this benefit to high- or very-high-risk patients without previous myocardial infarction or stroke. These findings support earlier, intensive and sustained LDL-cholesterol lowering. This review summarizes the main evidence supporting evolocumab across the cardiovascular risk continuum.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 10","pages":"597-603"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}