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Revue medicale de Liege最新文献

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[Sophie Vieujean, lauréate du Prix de la Fondation Docteurs Désiré et Maurice Jaumain 2024].
Revue medicale de Liege Pub Date : 2025-03-01
Jacques Boniver
{"title":"[Sophie Vieujean, lauréate du Prix de la Fondation Docteurs Désiré et Maurice Jaumain 2024].","authors":"Jacques Boniver","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>/.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"137-138"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Necrotizing dermo-hypodermitis of the upper limb after a moray eel bit].
Revue medicale de Liege Pub Date : 2025-03-01
Virginie Van Boeckel, Nicolas Francoeur, Nicolas Abboud, Jean-Luc Nizet
{"title":"[Necrotizing dermo-hypodermitis of the upper limb after a moray eel bit].","authors":"Virginie Van Boeckel, Nicolas Francoeur, Nicolas Abboud, Jean-Luc Nizet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A small number of complications from moray eel bites have been described to date. Wounds occurring in water provide a favourable context for infections by lesser-known micro-organisms. We share our experience of a case of necrotising dermo-hypodermatitis of the upper limb, emphasizing the importance of rapid diagnosis and the reconstructive dimension of our treatment.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"139-141"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Suicide seen through neuroscience and cerebral imaging].
Revue medicale de Liege Pub Date : 2025-03-01
Éric Constant
{"title":"[Suicide seen through neuroscience and cerebral imaging].","authors":"Éric Constant","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Suicide remains a major public health problem today. It is most often linked to an underlying psychiatric pathology, with major depression at the top of the list. But while the majority of suicided patients are depressed, the majority of depressed patients do not commit suicide. It is therefore necessary to identify this subgroup of depressed patients at risk for suicide. It presents a particularly risky diathesis for suicidal behaviour. Cognitive neurosciences help us to clarify this diathesis and identify these depressed patients at risk for suicide. This sometimes concerns emotional dysregulation and the misinterpretation of social signals emitted by others, sometimes the presence of aggressive or impulsive traits in decision-making and problem solving. Treating depression aggressively, including resistant depression, is therefore very important. Contrary to what had been advanced a few decades ago, the prescription of antidepressants does not increase the risk of suicide in the month following their introduction, and it is also the case in children and adolescents. New therapeutic options for resistant depression, such as esketamine or repetitive transcranial magnetic stimulation, are welcome.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"191-195"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intestinal fibrosis in Crohn's disease : towards new therapeutic options?]
Revue medicale de Liege Pub Date : 2025-03-01
Sophie Vieujean, Émeline Bequet, Marty Stepniak, Marie-Alice Meuwis, Édouard Louis
{"title":"[Intestinal fibrosis in Crohn's disease : towards new therapeutic options?]","authors":"Sophie Vieujean, Émeline Bequet, Marty Stepniak, Marie-Alice Meuwis, Édouard Louis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Crohn's disease is a chronic inflammatory bowel disease that can lead to fibrostenotic complications. These strictures result from an imbalance between inflammation and excessive healing, leading to an abnormal accumulation of extracellular matrix and a progressive thickening of the intestinal wall. To date, no specific treatment is available to prevent or reverse intestinal fibrosis. The management of strictures primarily focuses on controlling inflammation and addressing obstructive complications through endoscopic balloon dilation, stricturoplasty, or intestinal resection. Current medical therapies, such as anti-TNF agents, can help reduce inflammation but have no direct impact on fibrosis. New therapeutic strategies are emerging, including TL1A inhibitors (duvakitug, tulisokibart), an ALK5 inhibitor (AGMB-129), and targeted AGR2 therapies (TH-009). Additionally, mesenchymal stem cells are being investigated in our hospital center in combination with endoscopic balloon dilation, aiming to assess their therapeutic potential. The development of effective anti-fibrotic therapies remains a critical medical need to improve the management of intestinal strictures and reduce the need for invasive procedures in Crohn's disease.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"154-161"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[«PFAS», pollutants in the spotlight].
Revue medicale de Liege Pub Date : 2025-03-01
Patrice Dufour, Catherine Pirard, Corinne Charlier
{"title":"[«PFAS», pollutants in the spotlight].","authors":"Patrice Dufour, Catherine Pirard, Corinne Charlier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In November 2023, Wallonia was rocked by the discovery of problematic PFAS contamination of drinking water in the Chièvres region. PFAS («per- or polyfluoroalkyl substances») are compounds produced and used in large quantities by human activities for numerous applications, such as the formulation of fire-fighting foams, which appears to be at the origin of the pollution in Chièvres. The two main PFASs (perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS)) have been shown to have toxic effects on immunity, cholesterol metabolism, liver function and newborn birth weight. In addition, PFOA is classified as a definite human carcinogen. The Toxicology Department of Liège University Hospital has carried out numerous studies on these compounds and their impact on human health. In addition, we offer to measure them in patients' serum or breast milk, and provide patients and their doctors with an interpretation and follow-up proposal based on the results obtained. Environmental pollution by PFAS and its consequences demonstrate once again how the degradation of our environment and our health are closely linked.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"162-168"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Overview of therapeutic strategies for motor disturbances in Parkinson's disease].
Revue medicale de Liege Pub Date : 2025-03-01
Hilal Delgoffe, Gaëtan Garraux
{"title":"[Overview of therapeutic strategies for motor disturbances in Parkinson's disease].","authors":"Hilal Delgoffe, Gaëtan Garraux","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parkinson's disease is an adult neurodegenerative disorder whose prevalence continues to rise. There is no proven therapeutic strategy capable of interfering with its unfavourable evolutionary profile. Current treatments remain symptomatic. This article proposes to guide practitioners through the various therapeutic strategies for motor manifestations available in Belgium, from first-line drug treatments to the more complex options offered at the most advanced stages, such as deep brain stimulation or levo-dopa infusions. Regardless disease duration, maintaining quality of life involves essential complementary interventions such as regular physical exercise and physiotherapy. The multidisciplinary approach is strengthened according to individual needs as the disease progresses towards the complex stage.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"142-150"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Smoking and tobacco control : twenty years after the WHO Framework Convention on Tobacco Control].
Revue medicale de Liege Pub Date : 2025-03-01
Jean Perriot, Gérard Peiffer, Philippe Arvers, Valentin Flaudias
{"title":"[Smoking and tobacco control : twenty years after the WHO Framework Convention on Tobacco Control].","authors":"Jean Perriot, Gérard Peiffer, Philippe Arvers, Valentin Flaudias","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Smoking is the world's leading cause of preventable death. It is a risk factor or aggravating cause of many diseases and health problems : cancer, chronic obstructive pulmonary disease, cardiovascular disease, diabetes, HIV infection, tuberculosis and environmental health effects. The socioeconomic costs of smoking, already exorbitant, are likely to become unsustainable for all countries, particularly developing countries, by 2050. Twenty years after the implementation of the WHO Framework Convention on Tobacco Control (FCTC), this article aims to take stock of the situation regarding smoking and tobacco control. Strengthening tobacco control policies, including support for smoking cessation, is more important than ever to curb the tobacco pandemic and its devastating consequences.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"169-174"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Late-onset neutropenia following ocrelizumab treatment in relapsing multiple sclerosis].
Revue medicale de Liege Pub Date : 2025-03-01
Sarvnaz Shalchian Tehran, Aurélie Jaspers
{"title":"[Late-onset neutropenia following ocrelizumab treatment in relapsing multiple sclerosis].","authors":"Sarvnaz Shalchian Tehran, Aurélie Jaspers","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We are reporting two cases of late-onset severe neutropenia following treatment with ocrelizumab in patients with relapsing multiple sclerosis. These cases highlight a rare but clinically significant side effect of a widely used multiple sclerosis treatment. This article aims to raise awareness among clinicians regarding this potential hematological complication, emphasizing the importance of vigilant monitoring and early intervention. Through these cases, we discuss the underlying pathophysiological mechanisms. Additionally, we wish to emphasize the importance of a multidisciplinary approach to manage this complication, involving close collaboration between neurologists, hematologists, and other specialists.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"151-153"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Open necrosectomies after severe acute pancreatitis : is there still a place for it in 2024 ?]
Revue medicale de Liege Pub Date : 2025-03-01
Casimir Fleur Rahantasoa Finaritra, Nirina Nomenjanahary Rasamoelison, Warren Razanajatovo Niarison, Fanjandrainy Rasoaherinome Njanahary, Luc Hervé Samison
{"title":"[Open necrosectomies after severe acute pancreatitis : is there still a place for it in 2024 ?]","authors":"Casimir Fleur Rahantasoa Finaritra, Nirina Nomenjanahary Rasamoelison, Warren Razanajatovo Niarison, Fanjandrainy Rasoaherinome Njanahary, Luc Hervé Samison","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>the indication for pancreatic necrosectomy arises in a context of seriousness. Several factors can influence postoperative outcomes. Our objective is to identify the clinical and paraclinical factors which would influence the occurrence of complications after pancreatic necrosectomy.</p><p><strong>Patients and methods: </strong>it is a retrospective study of the postoperative outcomes of patients treated by pancreatic necrosectomy from January 1th, 2019 to December 31th, 2023.</p><p><strong>Results: </strong>fifty-nine cases were selected with sex ratio = 1.03 and mean age = 45 years [range 28;79]. The morbidity rate was 61 % (n = 36). The most frequent complication was postoperative hemorrhagic shock (n = 14) followed by septic shock (n = 12). Malnutrition, hyperleukocytosis, fasting > 5 days, bleeding > 500 ml, extensive necrosis (30 % - 50 %), a long stay in intensive care (> 5 days) were related to serious complications (p < 0.001). Antibiotic therapy, and the number of drains was not associated to the occurrence of severe morbidity.</p><p><strong>Conclusion: </strong>both the severity of the disease and the patient's condition were related to the prognosis. The right timing for surgery is recommended to avoid serious complications.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"175-181"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[How to optimize intraoperative frozen section examinations in pathology].
Revue medicale de Liege Pub Date : 2025-03-01
Stéphanie Rizzo, Marie-Sophie Kesteman, Gilles Leduc, Roland Greimers, Philippe Delvenne
{"title":"[How to optimize intraoperative frozen section examinations in pathology].","authors":"Stéphanie Rizzo, Marie-Sophie Kesteman, Gilles Leduc, Roland Greimers, Philippe Delvenne","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The intraoperative frozen section examination allows to offer to the surgeon relevant information which could change the patient intraoperative management. The sensitivity of this technique is limited by the size of the analysed sample and by cryogenisation's artefacts. The intraoperative consultations have to be performed for precise indications because some exams could be harmful. It is mandatory to be aware of different problems which could alter the intraoperative diagnosis: inadequate sampling, technical issues or insufficient communication between the surgeon and the pathologist. Nevertheless, the intraoperative frozen section examination remains a reliable procedure useful in many pathological contexts.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 3","pages":"196-200"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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