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Revue medicale de Liege最新文献

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[Bilateral papillary edema associated to immunotherapy]. [免疫治疗相关的双侧乳头状水肿]。
Revue medicale de Liege Pub Date : 2026-07-01
Cédric Orban, Maxime Dequinze
{"title":"[Bilateral papillary edema associated to immunotherapy].","authors":"Cédric Orban, Maxime Dequinze","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Immunotherapy has become the treatment of choice in a lot of metastatic diseases including melanoma, improving the prognosis. However, there are a lot of specific and multisystemic side effects. We report the case of a 68-year-old woman treated with combined immunotherapy for a metastatic melanoma who presented a severe right eye sight loss due to a papillary edema.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"438-442"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The diagnostic complexity of paraneoplastic thrombotic thrombocytopenic purpura]. [副肿瘤血栓性血小板减少性紫癜的诊断复杂性]。
Revue medicale de Liege Pub Date : 2026-07-01
Axelle Delcour, Laurent Jadot, Nassim Aït Moussa, Lyonel Herman, Quentin Perlot
{"title":"[The diagnostic complexity of paraneoplastic thrombotic thrombocytopenic purpura].","authors":"Axelle Delcour, Laurent Jadot, Nassim Aït Moussa, Lyonel Herman, Quentin Perlot","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thrombotic thrombocytopenic purpura (TTP) is a rare microangiopathy characterized by mechanical hemolytic anemia, thrombocytopenia, and multiorgan dysfunction, resulting from a severe deficiency of ADAMTS13. Among its rare forms, paraneoplastic TTP remains poorly described. We report here the case of a patient in the intensive care unit presenting with paraneoplastic TTP associated with metastatic prostate cancer. This case illustrates the diagnostic challenge posed by the interplay of multiple mechanisms and allows discussion of the different therapeutic options according to the type of TTP, including the role of plasma exchange in paraneoplastic TTP.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"415-419"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pseudotumor on metal debris after total hip arthroplasty]. 全髋关节置换术后金属碎片假瘤。
Revue medicale de Liege Pub Date : 2026-07-01
Erika Smets, William Kurth
{"title":"[Pseudotumor on metal debris after total hip arthroplasty].","authors":"Erika Smets, William Kurth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Total hip arthroplasty (THA) is the standard treatment for osteoarthritis of the hip, aseptic osteonecrosis of the femoral head and specific hip fracture. Adverse tissue reactions to metal debris are feared in total hip replacements using the metal-on-metal bearing surfaces. They can result in local and systemic toxicity or local hypersensitivity to metal. Additional investigations, including blood tests, radiography and nuclear magnetic resonance imaging (RMN), are essential to establish the diagnosis. Surgical revision of the prosthesis or the friction torque could be necessary.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"467-470"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Volontary poisoning with yew ( Taxus baccata) : a fatal case]. [红豆杉（Taxus baccata）自愿中毒：一例致命病例]。
Revue medicale de Liege Pub Date : 2026-07-01
Nassim Ait Moussa, Axelle Delcour, Philippe Morimont, Bernard Lambermont
{"title":"[Volontary poisoning with yew ( Taxus baccata) : a fatal case].","authors":"Nassim Ait Moussa, Axelle Delcour, Philippe Morimont, Bernard Lambermont","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Poisoning with Taxus baccata (common yew) is a life-threatening emergency due to its major cardiotoxicity. The taxines it contains block cardiac sodium channels, rapidly leading to severe arrhythmias, cardiogenic shock, and often cardiac arrest. Management is exclusively symptomatic and relies on intensive hemodynamic support, including advanced resuscitation and, in some cases, the use of extracorporeal circulatory support (ECMO). The administration of antidotes such as DigiFab®, although experimental and not formally validated for this indication, may be considered based on pharmacological analogies with digoxin.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"471-474"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Retinal intoxication with tamoxifen treatment for breast cancer]. 视网膜中毒联合他莫昔芬治疗乳腺癌。
Revue medicale de Liege Pub Date : 2026-07-01
Marine Pegolotti, Bénédicte Locht, Jean-Marie Rakic
{"title":"[Retinal intoxication with tamoxifen treatment for breast cancer].","authors":"Marine Pegolotti, Bénédicte Locht, Jean-Marie Rakic","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Breast cancer is often treated with tamoxifen, a drug that can cause ocular side effects, including toxic retinopathy. Multimodal imaging, particularly optical coherence tomography (OCT), has improved the detection of early lesions such as foveal pseudocysts, thus increasing the prevalence of this complication. We present a case of tamoxifen-induced retinopathy in a patient treated for four years who developed decreased visual acuity with irreversible retinal lesions in the right eye despite discontinuation of the treatment. OCT was essential in characterizing the lesions. The pathophysiology remains poorly understood, but involvement of Müller cells and glutamate accumulation in the retinal pigment epithelium are suspected. Toxicity depends on cumulative dose, duration of treatment, and individual factors. Initial ophthalmologic screening and regular OCT monitoring are recommended to detect retinal damage early. In case of lesions, substitution with an aromatase inhibitor is often considered to limit lesion progression and preserve vision.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"475-481"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Coronary artery anomalies associated with bicuspid aortic valve]. [冠状动脉异常与二尖瓣主动脉瓣相关]。
Revue medicale de Liege Pub Date : 2026-07-01
Samy Damès, Shayan Madani, Rodolphe Durieux, Vincent Tchana-Sato, Marc Radermecker
{"title":"[Coronary artery anomalies associated with bicuspid aortic valve].","authors":"Samy Damès, Shayan Madani, Rodolphe Durieux, Vincent Tchana-Sato, Marc Radermecker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bicuspid aortic valve (BAV) is the most common congenital heart disease. It is often associated with aortic abnormalities and, more rarely, with coronary anomalies that may influence surgical strategy. We describe a 38-year-old patient with a Sievers type I BAV. Coronary CT angiography revealed an abnormally high proximal origin of the right coronary artery, with a 10 mm ectatic dilation at its origin followed by a return to normal caliber. This feature prompted a change in operative strategy: mechanical aortic valve replacement instead of a Ross procedure, more distal aortic clamping, and a «lazy-S» aortotomy. The procedure was completed without complications. Coronary anomalies are more frequent in patients with BAV than in the general population. Their preoperative identification is essential to prevent intraoperative complications. Multimodal imaging plays a key role in optimizing surgical planning in line with current recommendations. Coronary anomalies associated with BAV should be systematically screened for before any valve surgery. This case highlights the importance of thorough preoperative assessment and appropriate technical adaptation to ensure operative safety.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"411-414"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Arthroscopy of the hip : modern times surgery]. 髋关节镜检查：现代外科手术。
Revue medicale de Liege Pub Date : 2026-07-01
Christopher Mettlen, Shayan Moradi
{"title":"[Arthroscopy of the hip : modern times surgery].","authors":"Christopher Mettlen, Shayan Moradi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hip arthroscopy is a minimally invasive surgical technique, introduced in the 1980s, which has profoundly transformed the management of intra-articular pathologies of this anatomical site. It effectively treats conditions such as labral tears or detachments or femoroacetabular impingement, reducing postoperative pain, complications and recovery times. Initially limited to simple diagnostic procedures, it has evolved thanks to technological advances towards more complex interventions, such as labral reinsertion, femoroplasty or the management of cartilage and ligament lesions. This clinical case illustrates its effectiveness: a 25-year-old young athlete suffering from a labral lesion and a CAM effect (due to an osseous asphericity of the femoral head) underwent arthroscopic labral suture, with complete disappearance of pain and a marked functional improvement (Harris score increased from 65 to 91). Scientific data confirm these results, showing high rates of return to sport, lasting improvement in articular function and a low rate of complications, consolidating arthroscopy as the benchmark in modern orthopedic surgery.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"448-453"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rotational physeal fracture of the distal tibia : where a keen clinical eye changes everything]. 【胫骨远端旋转骨骺骨折：敏锐的临床眼光可以改变一切】。
Revue medicale de Liege Pub Date : 2026-07-01
Mohamed Mamou, Nanni Allington
{"title":"[Rotational physeal fracture of the distal tibia : where a keen clinical eye changes everything].","authors":"Mohamed Mamou, Nanni Allington","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ankle fractures are among the most common pediatric fractures, especially during the transitional period. They can lead to growth arrest, which is why careful attention is required when interpreting radiographs. This article discusses the case of an 11-year-old patient who sustained a rotational injury to the left ankle. Initially protocoled as negative, a second review of the radiographs supplemented by a CT scan revealed a Salter-Harris type II fracture of the distal tibia with 90° external rotation, associated with a non-displaced fibula fracture. Treatment consisted of a closed reduction and cast immobilization. Follow-up revealed a growth arrest of the tibial physis at 6 months, leading to a preventive epiphysiodesis of the contralateral ankle. This case highlights the diagnostic challenges of rotational fractures, which are often underestimated in imaging. It also underlines the importance of clinical examination, which remains the clinician's primary tool. Finally, close monitoring of this type of fracture is essential due to its high risk of growth disturbance.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 7-8","pages":"443-447"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Developmental susceptibility to endocrine-disrupting chemicals in female reproductive health]. [女性生殖健康中对内分泌干扰化学物质的发育易感性]。
Revue medicale de Liege Pub Date : 2026-05-01
Marie-Azélie Moralia, Julie Fudvoye, Anne-Simone Parent
{"title":"[Developmental susceptibility to endocrine-disrupting chemicals in female reproductive health].","authors":"Marie-Azélie Moralia, Julie Fudvoye, Anne-Simone Parent","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Endocrine-disrupting chemicals are ubiquitous in ecosystems and in the human body, leading to continuous exposure throughout the lifespan. Their ability to interfere with hormonal signaling raises increasing concern about their effects on female reproductive health. This review synthesizes epidemiological and experimental evidence showing that key developmental periods - fetal life, childhood, and puberty - represent major windows of susceptibility. Endocrine-disrupting chemicals can impair the establishment and maintenance of the ovarian reserve, alter the neuroendocrine programming of puberty, and contribute to disorders such as the micropolycystic ovary syndrome. Overall, these observations highlight the importance of adopting a «One Health» perspective, as widespread environmental contamination simultaneously affects humans, wildlife, and ecosystems. Reducing exposure and implementing coordinated prevention policies are essential to protect reproductive health and global health.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"304-309"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The first 1,000 days of life : a period of vulnerability to environmental pollutants]. [生命最初的1000天：对环境污染物的脆弱期]。
Revue medicale de Liege Pub Date : 2026-05-01
Navin Xhenseval, Patrice Dufour, Catherine Pirard, Corinne Charlier
{"title":"[The first 1,000 days of life : a period of vulnerability to environmental pollutants].","authors":"Navin Xhenseval, Patrice Dufour, Catherine Pirard, Corinne Charlier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Research on the first 1,000 days, from conception to the end of the first two years of life, has highlighted the vulnerability of unborn children and newborns to environmental pollutants. Human exposure to these substances has become ubiquitous and contamination seems inevitable. Some environmental pollutants are endocrine disruptors, and their effects on this developing population are still poorly understood. The interference caused by chemicals with neurodevelopment, metabolism, and cell signaling has shown that early alterations in these processes can trigger chronic diseases later in life. The difficulties inherent in taking biological samples from fetuses and young children, as well as in assessing multiple contamination, make large-scale studies more complex but necessary to evaluate and quantify the impact of pollutants on this particularly vulnerable population. Preventing exposure to environmental pollutants, especially during the first 1,000 days of life, is a major public health issue and a potent lever for reducing the incidence of chronic diseases.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"81 5-6","pages":"299-303"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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