发布求助
文献互助 智能选刊 最新文献

Revue medicale de Liege最新文献

筛选
英文 中文
[Updated recommendations on metabolic dysfunction-associated steatotic liver disease]. [关于代谢功能障碍相关脂肪变性肝病的最新建议]。
Revue medicale de Liege Pub Date : 2025-05-01
Alice Dongier, Jean Delwaide, Édouard Louis, Jean-Philippe Loly
{"title":"[Updated recommendations on metabolic dysfunction-associated steatotic liver disease].","authors":"Alice Dongier, Jean Delwaide, Édouard Louis, Jean-Philippe Loly","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The updated recommendations on metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) emphasize the importance of early detection and clear terminology. MASLD includes hepatic fat accumulation linked to cardiometabolic factors, while its severe inflammatory form is termed metabolic dysfunction-associated steatohepatitis (MASH). Management follows a structured approach: first, clinicians identify risk factors such as obesity, diabetes, alcohol intake, and abnormal liver enzymes. Risk stratification relies on non-invasive tests (e.g., FIB-4 index or FibroScan®) to distinguish simple steatosis from progressive forms that can advance to cirrhosis and hepatocellular carcinoma. Precise assessment of alcohol consumption is also crucial, as it distinguishes MetALD (a combination of metabolic factors and alcohol use) from ALD (significant alcohol use), ensuring tailored treatment. Therapy priorities include lifestyle modifications (weight reduction, dietary changes, and regular physical activity) along with optimal management of comorbidities (diabetes, dyslipidemia) and targeted surveillance for complications. Pharmacological options, including potential future therapies targeting MASH, may be considered in cases of advanced fibrosis. Ultimately, these recommendations highlight the need for a multidisciplinary approach, combining hepatologists, diabetologists, and other specialists, to effectively identify and manage MASLD/MASH and improve long-term outcomes.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 5-6","pages":"401-409"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Management of soft tissue sarcomas : guidelines for the diagnosis and treatment]. 【软组织肉瘤的处理：诊断和治疗指南】。
Revue medicale de Liege Pub Date : 2025-05-01
Maud Neuberg, Emmanuel Decker, Christine Gennigens, Gilles Colin, Charles Pottier, Fréderic Lifrange, William Kurth, Arnaud De Roover
{"title":"[Management of soft tissue sarcomas : guidelines for the diagnosis and treatment].","authors":"Maud Neuberg, Emmanuel Decker, Christine Gennigens, Gilles Colin, Charles Pottier, Fréderic Lifrange, William Kurth, Arnaud De Roover","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Soft tissue sarcomas determine a rare heterogeneous group of tumours. Most important is the initial diagnostic procedure, comprising adequate imaging and a core needle biopsy. Management should be carried out in sarcoma reference centres. This would mean referring all patients with any suspected soft tissue sarcoma. Prior to surgery, a multidisciplinary conference determines its moment and the eventual need of neoadjuvant treatment. The standard surgical procedure is an \"en bloc\" excision. This implies removing the tumour in a single specimen with a rim of normal tissue around it.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 5-6","pages":"330-333"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Neonatal herpes infection : prevention and therapeutic management in mother and newborn]. 新生儿疱疹感染：母婴预防和治疗管理。
Revue medicale de Liege Pub Date : 2025-04-01
Loriane Horion, Julie Frère, Catherine Pieltain, Marie-Françoise Dresse
{"title":"[Neonatal herpes infection : prevention and therapeutic management in mother and newborn].","authors":"Loriane Horion, Julie Frère, Catherine Pieltain, Marie-Françoise Dresse","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neonatal herpes simplex virus (HSV) infection is an uncommon disease, but one with a high rate of morbidity and mortality. The disease may present with different features and variable symptoms, particularly during the neonatal period, which can lead to misdiagnosis. It is crucial to initiate antiviral treatment rapidly in order to reduce the risk of sequelae, and therefore it is important to identify this infectiont promptly. Furthermore, given that the disease is transmitted most frequently during the perinatal period, this article will discuss the prevention and management of the disease in pregnant women.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"204-207"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Adaptations and constraints : obstetrical complications in the light of phylogenesis]. [适应和限制：从系统发育角度看产科并发症]。
Revue medicale de Liege Pub Date : 2025-04-01
Xavier Capelle, Alix Doupagne, Christine Van Linthout, Sébastien Grandfils, Frédéric Kridelka
{"title":"[Adaptations and constraints : obstetrical complications in the light of phylogenesis].","authors":"Xavier Capelle, Alix Doupagne, Christine Van Linthout, Sébastien Grandfils, Frédéric Kridelka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Among mammals, our species is the one whose females pay the heaviest price during parturition. Maternal morbidity and mortality remain a major global public health issue.Recent advances in paleoanthropology and evolutionary biology have shed new light on the complexity and dangerousness of childbirth in modern humans, compared with the great apes. This evolutionary conception invites us to understand and represent obstetrical pathology differently.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"214-221"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[SURMOUNT-OSA study : tirzepatide improves obstructive sleep apnoea in patients with obesity]. [SURMOUNT-OSA研究：替西肽改善肥胖患者的阻塞性睡眠呼吸暂停]。
Revue medicale de Liege Pub Date : 2025-04-01
André Scheen
{"title":"[SURMOUNT-OSA study : tirzepatide improves obstructive sleep apnoea in patients with obesity].","authors":"André Scheen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tirzepatide is a unimolecular dual agonist of both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, which is developed as once-weekly subcutaneous injection. It has been developed in two huge research clinical programmes, SURPASS in type 2 diabetes and SURMOUNT in obesity. Obesity is often complicated by an obstructive sleep apnoea (OSA), which is associated with an increased morbidity and mortality. The controlled study SURMOUNT-OSA has been carried out in people with obesity and OSA, possibly already treated with a continuous positive airway pressure (CPAP). When compared to placebo, tirzepatide (10 or 15 mg/week) reduces body weight, diminishes the frequency and severity of sleep apnoea episodes, dampens hypoxia burden, lowers arterial blood pressure, reduces systemic inflammation and, in fine, improves the parameters of sleep quality reported by patients. Tirzepatide is indicated in the management of people with obesity or overweight who present at least one weight-related comorbidity factor among which OSA.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"251-257"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Investigation and treatment of metatarsalgia due to avascular osteonecrosis of a sesamoid]. [籽骨缺血性骨坏死所致跖骨痛的调查与治疗]。
Revue medicale de Liege Pub Date : 2025-04-01
Imane Bouyaara, Marie-Antoinette Ferrara, François Grailet, Jean-François Kaux
{"title":"[Investigation and treatment of metatarsalgia due to avascular osteonecrosis of a sesamoid].","authors":"Imane Bouyaara, Marie-Antoinette Ferrara, François Grailet, Jean-François Kaux","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Renander disease or avascular osteonecrosis of one (or two) sesamoid of the first metatarsal is a rare and poorly studied pathological entity. It is part of the differential diagnosis of metatarsalgia, a more common complaint in clinical practice. We report the case of a 14-year-old patient presenting with pain on the plantar area of the left first metatarsal, aggravated while fencing. Clinical examination and MRI suggested avascular osteonecrosis of the medial sesamoid, for which conservative treatment resolved the complaints. The presentation of this clinical case gives the opportunity to present a review of the diagnostic and therapeutic approaches of this pathology.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"234-240"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Diagnostic algorithm of fetal sex discordance in the era of genomic NIPT : clinical illustration and practical recommendation]. 【基因组NIPT时代胎儿性别不一致诊断算法：临床例证与实用推荐】。
Revue medicale de Liege Pub Date : 2025-04-01
Sophie Lorquet, Camille Chatelain, Marie Laterre, Julie Fudvoye, Alix Senterre, Aline Vanwynsberghe, Michelle Deberg, Jean-Stéphane Gatot, Saskia Bulk, Julie Harvengt
{"title":"[Diagnostic algorithm of fetal sex discordance in the era of genomic NIPT : clinical illustration and practical recommendation].","authors":"Sophie Lorquet, Camille Chatelain, Marie Laterre, Julie Fudvoye, Alix Senterre, Aline Vanwynsberghe, Michelle Deberg, Jean-Stéphane Gatot, Saskia Bulk, Julie Harvengt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The systematic reimbursement of non-invasive prenatal testing (NIPT) in Belgium has led to earlier diagnoses of fetal sex discordance. Variations in sex differentiation may be isolated or associated with more complex syndromic etiologies. Some genetic conditions necessitate prenatal diagnosis and early management, while other conditions do not require invasive prenatal testing. Thereby, implementation of diagnostic algorithms has become essential for the management of conditions underlying fetal sex discordance, to optimize obstetric follow-up and immediate neonatal care. Healthcare systems in each country should also be considered in these practical recommendations. This article proposes a decision tree for the management of fetal sex discordance with NIPT in Belgium, as illustrated by a clinical report of a newborn presenting a diagnosis of mixed gonadal dysgenesis.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"208-213"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hospital alcohol withdrawal : who, when, how]. [医院戒酒：何人，何时，如何]
Revue medicale de Liege Pub Date : 2025-04-01
Emeline Dogné, Gabrielle Scantamburlo
{"title":"[Hospital alcohol withdrawal : who, when, how].","authors":"Emeline Dogné, Gabrielle Scantamburlo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Alcohol consumption in Europe (and more specifically in Belgium) raises a major paradox: social alcohol or the scourge of the century? There are diagnostic criteria for recognizing substance use disorder (TUS) (according to the DSM-V). Healthcare professionals are daily confronted with this problem. This article looks at three key questions relating to hospital alcohol withdrawal, based on a specific situation. Only 10-30 % of alcohol withdrawals take place in hospital. There are clearly defined indications for hospitalization. It seems essential to work with patients on their objectives and to help them develop their motivation. It is in this context that pre-admission appointments are important. Pharmacologically, long-acting benzodiazepines are used in withdrawal, as are vitamin supplements and hydration. Hygiene and dietary rules are also reminded to the patient.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"258-264"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Twin Reversed Arterial Perfusion Sequence (TRAP) : a circulatory paradox causing complications in monochorial twin pregnancies]. 双胎动脉灌注逆转序列（TRAP）：导致单胎双胎妊娠并发症的循环悖论。
Revue medicale de Liege Pub Date : 2025-04-01
Emma Cornu, Violaine Emonard
{"title":"[Twin Reversed Arterial Perfusion Sequence (TRAP) : a circulatory paradox causing complications in monochorial twin pregnancies].","authors":"Emma Cornu, Violaine Emonard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The TRAP sequence («Twin Reversed Arterial Perfusion Sequence») is a rare condition found in approximately 1 to 3 % of monochorionic twin pregnancies. It results from the existence of placental vascular anastomoses (arterio-arterial and veno-venous) between a normal twin and an acardiac twin (or with a dysfunctional heart). The normal twin then serves as a «pump» for the abnormal twin who is retrogradely perfused. Throughout pregnancy, the well-being and survival of the pump twin is compromised by different mechanisms (risk of high-output heart failure, premature delivery, premature rupture of membranes, chronic hypoxia and delayed intrauterine growth). The diagnosis can be made from the 11th week of gestation using ultrasound and Doppler examination of the umbilical arteries. Although it is established that the mortality of pump twins is around 50 % in the absence of treatment, there is currently no consensus on the treatment methods nor on the timing to be respected. Some advocate an expectant attitude with close monitoring. Others prefer an intervention to interrupt blood flow to the acardiac twin. Intrafetal therapies by laser or radiofrequency are the most used methods at present. They appear safe and effective.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"222-226"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Predictive factors of non-invasive ventilation failure in patients with severe acute exacerbation of chronic obs-tructive pulmonary disease. Multicenter study]. 慢性阻塞性肺疾病严重急性加重期无创通气衰竭的预测因素。多中心研究。
Revue medicale de Liege Pub Date : 2025-04-01
Hamida Kwas, Houda Rouis, Sabrine Fehri Majdoub, Ines Zendah, Sonia Maalej, Habib Ghédira
{"title":"[Predictive factors of non-invasive ventilation failure in patients with severe acute exacerbation of chronic obs-tructive pulmonary disease. Multicenter study].","authors":"Hamida Kwas, Houda Rouis, Sabrine Fehri Majdoub, Ines Zendah, Sonia Maalej, Habib Ghédira","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Non invasive ventilation (NIV) has become an integral tool to assist patients with severe chronic obstructive pulmonary disease (COPD) exacerbation. However, the success of NIV in these patients remains relatively random and predictors of response are poorly known.</p><p><strong>Aim: </strong>To study the predictors of NIV failure in patients hospitalized for severe COPD exacerbation.</p><p><strong>Methods: </strong>Comparative and retrospective study including patients hospitalized for severe COPD exacerbation and who received NIV. Our work studied the predictive factors of NIV failure. Failure of NIV is defined by transfer to intensive care unit (ICU) with use of invasive ventilation.</p><p><strong>Results: </strong>Among the 268 patients hospitalized in the pulmonology department during the study period for COPD exacerbation, 68 (25.4 %) required the use of NIV. The average age was 60.8 ± 9.6 years. Sex ratio was 8.6. In multivariate analysis, cyanosis [Odds Ratio (OR) : 31.5; 95 % Confidence Interval (CI) : 4.5-221.9], heart rate ≥ 110 beats/min (OR : 10.1, 95 % CI : 1.9-52.9), signs of respiratory encephalopathy (OR : 6.6, 95 % CI : 1.4-32.1) and poor tolerance to NIV (OR : 5.9 % CI : 1.1-25.8) were associated with the ICU transfer.</p><p><strong>Conclusion: </strong>Presence at admission of cyanosis, tachycardia, signs of respiratory encephalopathy and poor tolerance to NIV are predictive factors for NIV failure in patients with severe COPD exacerbation.</p>","PeriodicalId":94201,"journal":{"name":"Revue medicale de Liege","volume":"80 4","pages":"227-233"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信