Neuro endocrinology letters最新文献

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Exploratory research on genetic polymorphisms associated with positive empathy and trait forgivingness among the Japanese. 关于日本人积极移情和特质宽容相关基因多态性的探索性研究。
Neuro endocrinology letters Pub Date : 2023-12-12
Masahiro Matsunaga, Yohsuke Ohtsubo, Takahiko Masuda, Yasuki Noguchi, Hidenori Yamasue, Keiko Ishii
{"title":"Exploratory research on genetic polymorphisms associated with positive empathy and trait forgivingness among the Japanese.","authors":"Masahiro Matsunaga, Yohsuke Ohtsubo, Takahiko Masuda, Yasuki Noguchi, Hidenori Yamasue, Keiko Ishii","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>Previous studies have indicated that good human relationships contribute significantly to subjective well-being. We recently focused on two important ways of developing good interpersonal relationships: positive empathy, which focuses on the happiness of other people, and trait forgivingness, a tendency to forgive others. We novelly conducted an exploratory genome-wide association study (GWAS) to identify candidate gene polymorphisms associated with positive empathy and trait forgivingness among the Japanese.</p><p><strong>Material and methods: </strong>We for the first time identified several genetic polymorphisms associated with positive empathy and trait forgivingness through the GWAS based on a small sample population and relatively low threshold. We subsequently validated three genetic polymorphisms from these candidate genes using a real-time polymerase chain reaction system.</p><p><strong>Results: </strong>The results demonstrated that polymorphism in the vomeronasal type-1 receptor 1 (VN1R1) (rs61744949), a putative human pheromone receptor, is associated with positive empathy. In addition, genetic polymorphisms in the 5-hydroxytryptamine (serotonin) receptor 7 (HTR7: rs77843021) and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon (YWHAE: rs9908013), which are associated with dopamine and serotonin biosynthesis, are associated with trait forgivingness.</p><p><strong>Conclusion: </strong>This study novelly illustrated the influence of the genetic polymorphism in VN1R1 on positive empathy and that of genetic polymorphisms in HTR7 and YWHAE on trait forgivingness. It identified a relationship between previously unreported genetic polymorphisms and the necessary abilities for developing good human relationships. This will significantly impact future research on positive psychology and social psychology.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 8","pages":"506-516"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinary microalbumin/creatinine ratio is a predictor of the occurrence and severity of leukoaraiosis. 尿微量白蛋白/肌酐比值可预测白癫风的发生和严重程度。
Neuro endocrinology letters Pub Date : 2023-12-12
PingPing Jin, ShanShan Ye, Hua Ye, QiaoWen Tong, QingYuan Zhang
{"title":"Urinary microalbumin/creatinine ratio is a predictor of the occurrence and severity of leukoaraiosis.","authors":"PingPing Jin, ShanShan Ye, Hua Ye, QiaoWen Tong, QingYuan Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the correlation between the urinary microalbumin/creatinine ratio (UACR) and the occurrence and severity of leukoaraiosis.</p><p><strong>Methods: </strong>A total of 323 patients were retrospectively recruited. Demographic, clinical, and laboratory data were collected at the time of admission, and the UACR was calculated based on the levels of urinary microalbumin and creatinine. All patients showed improvement in cranial magnetic resonance imaging (MRI) examination. The subjects were divided into leukoaraiosis and non-leukoaraiosis groups according to the results of the cranial MRI examination. According to the Fazekas standard score, the patients in the leukoaraiosis group were divided into the mild leukoaraiosis group: Fazekas (1-2 points), moderate leukoaraiosis group: Fazekas (3-4points); and severe leukoaraiosis group: Fazekas (5-6 points).</p><p><strong>Results: </strong>A regression analysis was performed to adjust for confounding factors. (1) Compared with the non-leukoaraiosis group, UACR level was higher in the leukoaraiosis group at admission, and the difference between the groups was statistically significant (p < 0.05). (2) In the multivariate logistic regression analysis, UACR was correlated with the occurrence of leukoaraiosis, which may be an independent risk factor. (3) The UACR levels increased gradually in the mild, moderate and severe leukoaraiosis groups, and the difference was statistically significant (p< 0.05). (4) In the ordered multi-category logistic regression analysis, UACR was correlated with the severity of leukoaraiosis, which may be an independent risk factor.</p><p><strong>Conclusion: </strong>UACR is associated with the occurrence and severity of leukoaraiosis, and may be an independent risk factor.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 8","pages":"528-536"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The correlation among Claudin-9, Tyrosine kinase-2, and Signal transducers and activators of transcription-3 expressions in non-functioning pituitary adenoma and invasiveness. 非功能性垂体腺瘤中Claudin-9、酪氨酸激酶-2和转录信号转导和激活因子-3的表达与侵袭性的相关性。
Neuro endocrinology letters Pub Date : 2023-12-12
Abudukadier Yasen, Maimaitiyiming Tuoheti, Ba Tu, Cheng Zhang, Yu Ding, Fey Tang, Yonggang Wu
{"title":"The correlation among Claudin-9, Tyrosine kinase-2, and Signal transducers and activators of transcription-3 expressions in non-functioning pituitary adenoma and invasiveness.","authors":"Abudukadier Yasen, Maimaitiyiming Tuoheti, Ba Tu, Cheng Zhang, Yu Ding, Fey Tang, Yonggang Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Deeper studies on the pathological mechanism associated with invasiveness of non-functioning pituitary adenoma (NFPA) is imperative to find better treatments. This research was preliminarily conducted to investigate the correlation between the expression of Claudin-9 (CLDN9), Tyrosine kinase-2 (TYK2), Signal transducers and activators of transcription-3 (STAT3) and invasiveness in NFPA to illustrate the pathological mechanism.</p><p><strong>Methods: </strong>Clinical data and surgical specimens of 12 patients with NFPA were collected and divided into invasive and non-invasive NFPA groups, comprising six patients for each group. CLDN9, TYK2 and STAT3 transcription and expression levels in the NFPA tissues of the two groups were detected by quantitative real-time polymerase chain reaction (qRT-PCR), Western blotting (WB) and immunohistochemistry (IHC). The lentiviral plasmid transfection technique was used to develop a rat pituitary tumour GT1-1 cell line null control group (NC) and CLDN9-overexpressed experimental group (OE-CLDN9), and TYK2 and STAT3 transcription levels in the NC and OE-CLDN9 cell groups were detected using qRT-PCR.</p><p><strong>Results: </strong>The CLDN9 and STAT3 expressions were significantly higher in invasive than in non-invasive NFPA tissues, whereas the TYK2 expression in invasive NFPA tissues was significantly lower than that in non-invasive NFPA (p < 0.001); The STAT3 upregulated (p < 0.001) and the TYK2 downregulated (p < 0.01) after the CLDN9 overexpression.</p><p><strong>Conclusion: </strong>Upregulated CLDN9 may increase the NFPA invasiveness through STAT3. In addition, low TYK2 expression might enhance the invasiveness in NFPA, which needs further studies to confirm. These results could provide a promising research leads for targeted treatment of NFPA.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 8","pages":"537-546"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combination therapy for patients with a developmental dysphasia: selected approaches based on special education, rehabilitation and psychology in a systematic case study. 发育性失语症患者的综合治疗:系统案例研究中基于特殊教育、康复和心理学的选定方法。
Neuro endocrinology letters Pub Date : 2023-12-12
Michal Vostrý, Ilona Pešatová, Barbora Lanková, Otakar Fleischmann, Jaroslava Jelínková, Ivana Štolová, Radka Beranová, Nikola Mundoková
{"title":"Combination therapy for patients with a developmental dysphasia: selected approaches based on special education, rehabilitation and psychology in a systematic case study.","authors":"Michal Vostrý, Ilona Pešatová, Barbora Lanková, Otakar Fleischmann, Jaroslava Jelínková, Ivana Štolová, Radka Beranová, Nikola Mundoková","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>The paper deals with the possibilities of the development and the support of individuals with developmental dysphasia with regard to the legislative framework of the Czech Republic in the field of education and presents the results of a systematic case study of a child patient diagnosed with developmental dysphasia (according to ICD-10; F80.1 and F80.2).</p><p><strong>Case report: </strong>The study aimed to determine the effect of combined therapy using long-term special educational, rehabilitation and psychological intervention, speech therapy and music therapy on the development of the patient's communication skills. The proband was selected by random, stratified sampling based on pre-determined relevant characteristics (age 6 years i.e., before entering primary school, diagnosed with developmental dysphasia). A 6-year-old child patient participated in the research with the consent of the legal representative. The therapy was focused on special educational care, speech therapy, music therapy and psychological intervention (including psychotherapy). During the hospitalization and post-hospitalization care, there was also the presence of a physiotherapist and an occupational therapist.</p><p><strong>Conclusion: </strong>The results of the research point out the need for regular and close multidisciplinary cooperation of an occupational therapist, a physiotherapist, a special educator, a speech therapist, a music therapist and a psychologist when working with patients diagnosed with developmental dysphasia. These professions focus specifically on specific areas of support with a focus on cognitive, phatic and motor functions with the support of social adaptability.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 8","pages":"517-527"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss of Consciousness and Prolonged Convulsions Due to Amanita Pantherina Intoxication. 天南星中毒导致意识丧失和长时间抽搐。
Neuro endocrinology letters Pub Date : 2023-12-12
Lukáš Handl, Martin Nováček, Robin Šín, Lenka Čechurová
{"title":"Loss of Consciousness and Prolonged Convulsions Due to Amanita Pantherina Intoxication.","authors":"Lukáš Handl, Martin Nováček, Robin Šín, Lenka Čechurová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Loss of consciousness ranks among very common causes for emergency medical service actions and is common occurrence in the emergency department. Its differential diagnosis is very broad and includes many possible causes, not in the least an intoxication. The same applies to convulsive states. Clinical course of mushroom poisoning varies depending on the particular fungal species, with some of the species causing loss of consciousness. One typical representative of such species is panther cap (Amanita pantherina). This case report introduces panther cap poisoning, initially presenting in given patient as coma and protracted generalized convulsions. Complex treatment led to withdrawal of neurologic symptoms, circulatory and metabolic stabilisation and subsequent discharge without signs of permanent organ damage.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 8","pages":"500-505"},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Job Types on Plasma Neurotrophins Levels: A Preliminary Study in Airline Pilots, Construction Workers, and Fitness Instructors. 工作类型对血浆神经营养素水平的影响:航空飞行员、建筑工人和健身教练的初步研究。
Neuro endocrinology letters Pub Date : 2023-10-23
Piercarlo Minoretti, Andrés S Santiago Sáez, Ángel F García Martín, Miryam Riera, Manuel Gómez Serrano, Abdelilah Lahmar, Enzo Emanuele
{"title":"Impact of Job Types on Plasma Neurotrophins Levels: A Preliminary Study in Airline Pilots, Construction Workers, and Fitness Instructors.","authors":"Piercarlo Minoretti, Andrés S Santiago Sáez, Ángel F García Martín, Miryam Riera, Manuel Gómez Serrano, Abdelilah Lahmar, Enzo Emanuele","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Neurotrophins (NTs) encompass a group of closely associated proteins regulating various aspects of neuronal growth and survival. The potential association between work-related factors and the levels of circulating NTs has not been extensively examined. In this preliminary investigation, we evaluated plasma concentrations of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4) in a cohort of healthy individuals from three distinct professional categories, each with unique work environments and lifestyle factors.</p><p><strong>Methods: </strong>The study involved 60 men from three professional fields: airline pilots, construction laborers, and fitness trainers (20 participants per category) recruited during routine occupational health appointments. Plasma levels of NTs were measured using commercially available immunoassays and compared in the three professional groups.</p><p><strong>Results: </strong>Among the professions studied, fitness instructors displayed the highest concentrations of BDNF and NGF, with airline pilots ranking second, and construction workers showing the lowest levels. Significantly decreased NT-3 levels were observed in airline pilots compared to fitness instructors and construction workers, but no differences were found between the latter two occupations. NT-4 levels were similar across all three occupational groups.</p><p><strong>Conclusions: </strong>Our pilot results suggest that plasma concentrations of NTs, which are involved in various aspects of neuronal and cognitive functioning, may display significant differences among healthy individuals depending on their occupation. These observations warrant additional research to explore potential implications for the field of occupational medicine.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 7","pages":"439-443"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49695569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Thyrotoxic Myopathy Combined with Neck Pain: A Case Report. 急性甲状腺毒性肌病合并颈部疼痛1例报告。
Neuro endocrinology letters Pub Date : 2023-10-23
Shi-En Fu, Xing-Huan Liang, Zhi-Ping Tang, Ya-Qi Kuang, Cheng-Cheng Qiu, Xiao-Fan Liu, Hai-Yan Yang, Zhen-Xing Huang, Ying-Fen Qin, Yan Ma, Zuo-Jie Luo
{"title":"Acute Thyrotoxic Myopathy Combined with Neck Pain: A Case Report.","authors":"Shi-En Fu, Xing-Huan Liang, Zhi-Ping Tang, Ya-Qi Kuang, Cheng-Cheng Qiu, Xiao-Fan Liu, Hai-Yan Yang, Zhen-Xing Huang, Ying-Fen Qin, Yan Ma, Zuo-Jie Luo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Acute thyrotoxic myopathy (ATM) is a rare and potentially lethal complication of thyrotoxicosis. The typical clinical symptoms of ATM are characterized by bulbar paralysis. Reports of the successful treatment of ATM are sporadic due to its low incidence. However, no English literature has reported Chinese patients with ATM and neck pain. Here, we report for the first time a Chinese patient with ATM and neck pain who recovered through large doses of systemic glucocorticoids and one intrathyroidal steroid injection.</p><p><strong>Case report: </strong>A 23-year-old woman visited our hospital with a two-year history of progressive weakness of her bulbar muscles, hoarseness, cough when swallowing, dysphagia, and a one-month history of recurrent painful swelling of the thyroid gland. She was diagnosed with ATM, chronic thyrotoxic myopathy (CTM), and Graves' ophthalmopathy (GO) due to Graves' disease (GD). After she was treated with a combination of low-dose glucocorticoids, antithyroid drugs (ATDs), propranolol, and ultrasound-guided percutaneous intrathyroidal injection of glucocorticoids, her bulbar paralysis, proximal myopathy, and neck pain simultaneously improved without recurrence during follow-up. To our knowledge, this is the first case report of a patient with ATM, CTM, GD, GO and neck pain treated by administering a combination of low-dose glucocorticoids, one intrathyroidal steroid injection and antithyroid agents.</p><p><strong>Conclusions: </strong>Clinicians should consider ATM and intervene with aggressive glucocorticoid therapy, and this is the key to reversing the progression of ATM when a patient has bulbar paralysis and thyrotoxic symptoms. Our case report references the clinical diagnosis and treatment of such cases.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 7","pages":"427-431"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49695564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral Performance Category score in patients after out-of-hospital cardiac arrest. 院外心脏骤停患者的脑功能类别评分。
Neuro endocrinology letters Pub Date : 2023-10-23
Robin Šín, Lenka Čechurová, Jiří Růžička, Denisa Štruncová, Lukáš Handl, Miroslav Urban, Ivo Prcín, Jana Kruba Vidunová, Pavel Hrdlička
{"title":"Cerebral Performance Category score in patients after out-of-hospital cardiac arrest.","authors":"Robin Šín, Lenka Čechurová, Jiří Růžička, Denisa Štruncová, Lukáš Handl, Miroslav Urban, Ivo Prcín, Jana Kruba Vidunová, Pavel Hrdlička","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Reporting epidemiological data on prehospital cardiac arrest in the Pilsen Region in 2022. Expression of cardiopulmonary resuscitation success using the Cerebral Performance Category (CPC) score.</p><p><strong>Materials and methods: </strong>The study looked at the survival rate of out-of-hospital sudden cardiac arrest in all patients in whom emergency medical services performed cardiopulmonary resuscitation (CPR). The study covered the period from 1 January 2022 to 31 December 2022. Both electronic and paper medical records were used to obtain data. All cases were evaluated according to Utstein-style guidelines.</p><p><strong>Results: </strong>During the studied period, emergency response teams in the Pilsen Region carried out CPR in 499 cases. The incidence of prehospital CPR was 88.43 cases per 100,000 population. A total of 146 patients (29.26%) were referred to the hospital with spontaneous circulation, and results indicating survival with a good neurological outcome of CPC 1 or 2 were recorded in 48 cases (9.62%). The first monitored rhythm was shockable in 119 cases (23.85%). In this subgroup, ROSC was achieved in 71 cases (59.66%) and 61 of them (51.26%) were referred to hospital. In this study subgroup, a total of 36 patients (30.25%) achieved a good neurological outcome with a CPC score of 1 or 2.</p><p><strong>Conclusion: </strong>The study presented epidemiological data on OHCA and prehospital CPR in the Pilsen region in 2022. The data obtained shows a survival rate with good neurological outcome in 9.62% of cases.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 7","pages":"482-488"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49695565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the timing of surgery affect short-term prognosis in newborn infants with meningomyelocele? 手术时机是否会影响新生儿脊膜膨出的短期预后?
Neuro endocrinology letters Pub Date : 2023-10-23
Mustafa Kurthan Mert, Ali İhsan Ökten
{"title":"Does the timing of surgery affect short-term prognosis in newborn infants with meningomyelocele?","authors":"Mustafa Kurthan Mert, Ali İhsan Ökten","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of postnatal primary repair surgery time on short-term (first 30 days) prognosis in newborns with Meningomyelocele (MMC).</p><p><strong>Methods: </strong>The study was conducted in the neonatal intensive care unit at a tertiary training and research hospital. The records of 41 MMC neonates were retrospectively reviewed. Demographic and clinical characteristics, surgical time, hospitalization and antibiotic duration, complications and associated anomalies were recorded.</p><p><strong>Results: </strong>There were 18 newborns in the early surgery (≤3 days) group and 23 newborns in the late surgery (>3 days up to 30 days) group.. There was no difference between groups in terms of birth weight, gestational week, head circumference, sex and type of delivery (p > 0.05). The length of hospitalization (17.2 ± 8.2 days vs 24.8 ± 16.1 days, p > 0.05) and antibiotic duration (11.8 ± 7.6 days vs 13.8 ± 10.1 days, p > 0.05) did not have significant difference. The number of neonates reoperated in the first 30 days was similar in early surgery group and in late surgery group (5 (27.7%) vs 6 (26.1%), p > 0.05). The number of patients requiring ventriculoperitoneal shunt was 9 (50%) in the early surgery group and 13 (56.5%) in the late surgery group. Surgical complications such as minor-major wound dehiscence, cerebrospinal fluid leakage, local infection, meningitis and ventriculitis were not statistically different between the groups (9 (50%) vs 8 (34.8%), (p > 0.05).</p><p><strong>Conclusion: </strong>Surgical complications were not statistically different between the early and late surgery group, although the presence of surgical complications may be effective in the short-term prognosis of MMC.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 7","pages":"475-481"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49695566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ever and Exclusive Breastfeeding Practice During the First Six Months of Infants' Life in Bahrain: A Cross-Sectional Study. 巴林婴儿出生前六个月的持续纯母乳喂养实践:一项横断面研究。
Neuro endocrinology letters Pub Date : 2023-10-23
Fajer A Nasser, Sohair Mohammed
{"title":"Ever and Exclusive Breastfeeding Practice During the First Six Months of Infants' Life in Bahrain: A Cross-Sectional Study.","authors":"Fajer A Nasser, Sohair Mohammed","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to determine the prevalence of mothers practicing ever and exclusive breastfeeding for the first six months of life in Bahrain, a high-income country, and determine the variables associated with ever and exclusive breastfeeding.</p><p><strong>Methods: </strong>This cross-sectional interview study on breastfeeding patterns was conducted on 345 women attending the Well Baby Clinic during their regular childcare visits at the Bahrain Defense Force Hospital from January 2019 to June 2019. Eligible women had at least one newborn aged six months to two years. The prevalence of ever and exclusive breastfeeding and its associated variables were analyzed using Chi-square and multivariate logistic regression and addressed by the odds ratio (OR) and respective 95% confidence interval (95% CI).</p><p><strong>Results: </strong>During the first six months of the infant's life, 56% (95% CI: 50.8%-61.5%) of mothers breastfed their infants, but only 5.5% (95% CI: 3.3%-8.5%) practiced exclusive breastfeeding. The multivariate logistic regression results showed that women were less likely to practice ever breastfeeding in the age group of 20-24 years (OR = 0.399, 95% CI: 0.167-0.953, p < 0.05) and had low education levels (OR = 0.388, 95% CI: 0.184-0.881, p < 0.05). Besides, mothers on contraceptives were not associated with ever breastfeeding (OR=1.926, 95% CI: 1.100-3.373, p < 0.05). Furthermore, the multivariate analysis revealed that mothers who had infants born with chronic disease were more likely to exclusively breastfed them (OR = 4.183, 95% CI: 1.138-15.378, p < 0.05). On the other hand, a significant association existed between women who did not have antennal care and exclusively breastfeeding (OR = 3.951, 95% CI: 1.460-10.692, p < 0.01). Furthermore, the main reason reported by mothers for not ever or exclusively breastfeeding was insufficient breast milk. Besides, difficulty during breastfeeding was another primary reason for not ever breastfeeding.</p><p><strong>Conclusion: </strong>The prevalence of exclusive breastfeeding is very low in Bahrain. To increase the exclusive breastfeeding prevalence rate, education programs and intervention studies, protocols, and training on overcoming mothers' challenges during breastfeeding must be implemented to increase exclusive breastfeeding rates.</p>","PeriodicalId":94154,"journal":{"name":"Neuro endocrinology letters","volume":"44 7","pages":"465-474"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49695568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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