Confusing cause and effect in public health policy.

Neuro endocrinology letters Pub Date : 2024-04-07
Andrea Bevelaqua, Claus Muss
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Abstract

When studying the literature on current public health policy challenges, a number of rankings can be found, created from data collected and processed by different methods and from different sources, ordering the challenges by their significance. Inevitably, in global studies, there are errors caused by averaging data across populations that differ significantly in population size and the causes of the decline in disability-adjusted life years (DALYs), potentially in combination with years of life lost (YLL) and years of life lived with disability (YLD), that may serve as indicators of the health status of a given population (Lopez 2005). Averaging data from populations that differ significantly in size, the larger population dominates and the main causes of health problems may be the same in both populations, and malnutrition and infectious diseases should be targeted, although in the smaller population cardiovascular disease is the main risk. A study published in 2018 shows that there are significant differences between countries and regions in the causes of the decline in DALYs and the increase in YLL and YLD (Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017 2018). Some similarities in the order of factors influencing the above indicators can be found in populations with comparable economic performance. In the so-called developed countries, demographic development, in other words, low birth rates resulting in aging of the population, and a significant increase in psychological disorders, are considered to be the core problem (Walker et al. 2015). Caution is needed in assessing the latter issue; bias may arise because mental health is given more attention in developed countries than in areas where even basic needs such as sufficient food and drinking water are not fully met, or where stressors such as military conflict or terrorism are present. On the other hand, lifestyles, associated with an abundance or surplus of resources and, thanks to generous social systems, the risk of dissolving the line between work and reward and the consequent absence of meaningful activity can pose a risk to the development of mental disorders (Dogra et al. 2022; Kim et al. 2013). Even with a cautious approach to global data, time is another factor that increases the opacity of the public health landscape. Over the last 30 years, there has been a significant rearrangement in the ranking of the most important factors influencing DALYs, YLL, and YLD. The top spot occupied in 1990 by lower respiratory tract infections has been taken by coronary heart disease in 2020, diarrheal diseases by unipolar depression and perinatal conditions, perhaps somewhat surprisingly, by traffic accidents (Anish and Sreelakshmi 2013).

在公共卫生政策中混淆因果关系。
在研究有关当前公共卫生政策挑战的文献时,可以发现一些排名,这些排名是通过不同方法和不同来源收集和处理的数据创建的,按挑战的重要性排序。在全球研究中,不可避免地会出现一些误差,这些误差是由人口规模和残疾调整寿命年数(DALYs)下降的原因(可能与损失寿命年数(YLLs)和残疾寿命年数(YLDs)结合在一起)造成的,而残疾调整寿命年数可作为特定人口健康状况的指标(Lopez,2005 年)。将规模相差悬殊的人群的数据进行平均,规模较大的人群占主导地位,而造成健康问题的主要原因在这两个人群中可能是相同的,营养不良和传染病应成为目标,尽管在规模较小的人群中,心血管疾病是主要风险。2018 年发表的一项研究显示,在 DALYs 下降以及 YLL 和 YLD 上升的原因方面,不同国家和地区之间存在显著差异(Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017 2018)。在经济表现相当的人群中,可以发现影响上述指标的因素顺序有一些相似之处。在所谓的发达国家,人口发展,换句话说,低出生率导致人口老龄化,以及心理障碍的显著增加,被认为是核心问题(沃克等人,2015 年)。在评估后一个问题时需要谨慎;可能会出现偏差,因为发达国家对心理健康的关注度高于那些连充足的食物和饮用水等基本需求都无法完全满足的地区,或存在军事冲突或恐怖主义等压力因素的地区。另一方面,与资源丰富或过剩有关的生活方式,以及慷慨的社会制度,有可能使工作与报酬之间的界限消失,从而导致缺乏有意义的活动,这些都有可能引发精神障碍(Dogra 等人,2022 年;Kim 等人,2013 年)。即使对全球数据采取谨慎的态度,时间也是增加公共卫生状况不透明性的另一个因素。在过去的 30 年中,影响残疾调整寿命年数(DALYs)、健康寿命年数(YLL)和健康寿命年数(YLD)的最重要因素的排名发生了重大变化。1990 年排名第一的是下呼吸道感染,到 2020 年已被冠心病取代;腹泻疾病被单极抑郁症取代;围产期疾病则被交通事故取代,这或许有些出人意料(Anish 和 Sreelakshmi,2013 年)。
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