Mymensingh medical journal : MMJ最新文献

{"title":"Demographics, Clinical Characteristics and Outcomes of 123 Cases of Coronavirus Disease (Covid-19) with Anosmia.","authors":"F Malik, M Kalimuddin, M Ishraquzzaman, M A A Mamun, N Ahmed, M Badiuzzaman, M N Ahmed, D Banik, T S Huq, S R Choudhury","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Anosmia has been recently recognized as a symptom of coronavirus disease (Covid-19). This study aimed to define demographics, the clinical course of anosmia in relation to other clinical symptoms, outcome of anosmia in Covid-19 positive patients. This cross-sectional study including all consecutive patients with confirmed Covid-19 from March 8th 2020 to March 7th 2021 at the National Heart Foundation Hospital & Research Institute of Bangladesh. There was subjective evaluation of olfactory function. A total of 769 patients were included in this study. Of whom 123(16.0%) patients had anosmia and 646 (84.0%) were without anosmia. Patients with anosmia were younger (37.07±13.23 years vs. 50.27±15.16 years), predominantly female (52.0% vs. 48.0%) and had fewer co-morbidities (p=0.001). Fever (87.8% vs. 61.0%), fatigue (74.8% vs. 18.9%), cough (60.2% vs. 32.7%), body ache (53.7% vs. 11.9%) and headache (52.0% vs. 9.9%) were the most common findings in patients with anosmia. Nasal congestion symptoms were more prevalent in patients with anosmia {32 cases (26.01%)} compared to patients without anosmia {38 cases (5.88%)} (p=0.001). Most of the patients with anosmia were treated either in home isolation or in institutional isolation (74.8% vs. 16.3%) and most of the patients without anosmia were hospitalized (83.7% vs. 25.2%). Patients with anosmia had milder course and good in-hospital outcome [0% case fatality rate (CFR) vs. 4.2% CFR; p=0.02] as compared to patients without anosmia. Patients with anosmia are usually younger and more frequently female, have a less co-morbidity, a milder course, a lower probability of hospitalization, and associated with favorable prognosis as compared with patients without anosmia.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"854-865"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship of Intima-Media Thickness of Common Carotid Artery in Acute Ischemic Stroke.","authors":"S S Rahman, M Bhattacharjee, F Ahmed, E Mia, M Saiduzzaman, S I Bhuiyan, M K Linckon, P A Khan, S Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Stroke is the second leading cause of death and third leading cause of disability which is associated with many risk factors. The progression of Carotid Intima Media Thickness (CIMT) has been established as a strong predictor of future vascular events recently. The purpose of this study was to assess the association between CIMT and acute ischemic stroke. This cross sectional comparative study was conducted in the Department of Neurology and Medicine, at Mymensingh Medical College Hospital, Bangladesh from January 2019 to September 2020. Total 120 patients (60 cases of acute ischemic stroke and 60 age and sex matched apparently healthy controls) were included in the study. Participants were studied for the presence of atherosclerotic risk factors and CIMT by high resolution ultrasonography. Mean age of the patients with acute ischemic stroke was 62.85±9.30 years and 70.0% were male. No significant difference was noted between cases and controls in terms of age, sex, occupation, education and socioeconomic class. The mean right CIMT in the patient group was 0.94±0.24mm and it was 0.66±0.19mm in the control group (p<0.001). The mean left CIMT in the patient group was 0.97±0.30mm and it was 0.63±0.18mm in the control group (p<0.001). The average CIMT in the patient group was 0.96±0.23mm and it was 0.65±0.17mm in the control group (p<0.001). CIMT was found to be higher among acute ischemic stroke patients who were smoker and hypertensive than that of nonsmoker and normotensive stroke patients. On multivariate analysis, CIMT remained associated with ischemic stroke as compared to other variables {OR 4.53, 95% CI 1.57-13.05), p<0.01}. CIMT measurements are independent markers of acute ischemic stroke.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"759-764"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Resistive Index to Differentiate between Prerenal Acute Kidney Injury and Acute Tubular Necrosis.","authors":"S Mahjabin, M N Islam, R Rahman, M Akhter, M E Mobin, F Nobi, N Hasan, B Sarker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acute kidney injury (AKI) a life threatening condition, one of the most dreadful disease with a broad etiological profile, a challenging problem in our community and specially in critically ill patients and also associated with high morbidity and mortality. Accurate and rapid diagnosis of the cause of AKI is particularly important for selecting appropriate therapy. Measurement of renal indices is commonly used to differentiate prerenal AKI from ATN, often cannot be used and also may not be accurate in many conditions. As renal biopsy is gold standard but this invasive procedure may not be feasible in critically ill patients. Therefore, this cross sectional study was conducted among patients with AKI at Department of Nephrology in Dhaka Medical College Hospital, Bangladesh from November 2017 to June 2019, to assess the ability of Resistive index (RI) to differentiate prerenal AKI and ATN. Mean age were 39.45±10.96 years, with male 65.0%. Among all, 19.0% of AKI patients were found to be sepsis followed by acute watery diarrhea (17.5%), when all causes of hypovolemia were combined, hypovolemia constituted the most prevalent cause. According to renal indices 47.0% patients had prerenal AKI and 53.0%, ATN. On the basis of RI, about 45.0% patients were as a case of prerenal AKI with mean RI 0.63±0.07 and 55.0% were ATN with Mean RI 0.77±0.71. But, type of AKI based on clinical diagnosis was considered as standard and were 46.0% prerenal AKI and 54.0% patients ATN. When compared with clinical diagnosis, RI was found to be more correlated with clinical diagnosis with p<0.001 than renal indices. RI had 91.89% sensitivity and 95.35% specificity to differentiate prerenal AKI and ATN. On the other hand, renal indices had low sensitivity (62.16%) and specificity (65.12%). Moreover, a statistically significant difference were noted between type of AKI diagnosed by RI and by renal indices (p<0.05). So, RI derived from Doppler ultrasound is superior to renal indices and can be used as a useful differentiating tool.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"777-785"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usage Pattern and Health Impact of Social Media on School-going Adolescents in Dhaka, Bangladesh.","authors":"N Ray, M K Khan, F N Islam, M A Amin, S T Rahman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Social media has become an essential tool for communication, information and entertainment and the use of the internet is increasing among adolescents. This study aimed to understand the usage pattern of social media among school-going adolescents and explore its health impacts. This cross-sectional study was conducted in secondary and higher secondary schools in old Dhaka city of Bangladesh among 248 adolescent students from February 2022 to July 2022. Data were collected through face-to-face interviews and analyzed using the STATA 16 SE version. Most students were 17-19 years old (71.37%) and 66.94% were male. Facebook (90.73%) was the most used social media, followed by Messenger (90.32%), YouTube (85.48%), WhatsApp (55.47%), Instagram (52.42%) and TikTok (12.30%). Students who go to bed after midnight (p=0.02), daily usage of Facebook >2 hours (p=0.02), daily usage of Messenger >2 hours (p<0.01), daily usage of WhatsApp ≥1 hour (p=0.01) and daily usage of Instagram ≥1 hour (p=0.03) were significantly associated with headache. Similarly, for students who go to bed after midnight (p=0.04), daily usage of Facebook >2 hours (p<0.01), daily usage of Messenger >2 hours (p<0.01), daily usage of YouTube ≥1 hour (p<0.01) and daily usage of TikTok ≥1 hour (p=0.04) were significantly associated with Eye Ache. Besides, students who go to bed after midnight (p=0.03) and daily usage of Facebook >2 hours (p=0.04) were significantly associated with interrupted sleep at night. The study found that many students suffer negative health consequences from social media use. Parents should take necessary steps to combat the health hazards of using excessive social media with their children.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"625-635"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Some Aspects of Hematological Status in Male Patients with Stable Chronic Obstructive Pulmonary Disease.","authors":"M Pervin, K Jahan, S Jahan, H M A Rashid, A A Jelly, K Fatema","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic Obstructive Pulmonary Disease (COPD) is one of the top three causes of death worldwide that induces an economic and social burden which is both substantial and increasing. Hematological status may be altered even in stable COPD and which is inversely related with the forced expiratory volume in first one second of expiration (FEV1). The objective of the study was to assessthe hematological status in stable COPD patients by counting their neutrophil, lymphocyte and platelet and to correlate them with FEV1. This cross-sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh from January 2010 to December 2010. Sixty (60) male smoker (5-10 pack /year) patients of stable COPD (FEV₁/FVC% <0.70; FEV₁ ≤80%; without any exacerbation for last 4 weeks) were randomly selected from the Out Patient Door (OPD) of Medicine Department, BSMMU and a private clinic in Dhaka. On the basis of spirometric findings, 30 mild (Group B1) and 30 moderate stages (Group B2) of COPD patients with age 35-45 years were included in this study. As control (Group A) 30 apparently healthy male persons with matched age, BMI and smoking status were studied. Neutrophil and lymphocyte were counted manually by compound microscope, slide and Leishman's stain. Total count of platelet was counted manually by using hemocytometer and platelet counting fluid through direct method. Data was expressed as mean±SD. The mean±SD of neutrophil were 52.3±4.82, 57.3±5.09 and 71.0±5.5; lymphocyte were 30.7±5.37, 28.4±6.98 and 22.5±4.40% and platelet count were 207.3±19.66, 242.5±40.32 and 281.8±55.46 per mm³ of blood in Group A, B₁ and B₂ respectively. For statistical analysis Independent sample t-test and Pearson's Correlation Coefficient test were performed, as applicable and p<0.05 was accepted as significant. In this study, the mean values of differential count of neutrophil were higher and lymphocytes were lower in both the study groups than control and also in B₂ to that of the B₁. The mean values of platelet were higher in both control and also in B₂ to that of the B₁. These differences of mean values among the groups were statistically significant at (p<0.001) in A vs. B₁ and A vs. B₂ but at (p<0.01) in B₁ vs. B₂. However, this result was non significant for lymphocyte count in B₁. Hematological status altered in stable COPD and this alteration is inversely related to the severity of the disease.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"720-727"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annular Conjunctival Autograft (ACAU): Modified Technique for Ocular Surface Reconstruction in Unilateral Chemical Burn.","authors":"S K Biswas, S R Roy, A S M Alam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chemical burns due to calcium hydroxide are common among all ages in the Indian subcontinent causing corneal blindness and disfigured eyes. Here, we applied a modified surgical procedure to assess the surgical outcome of a unilateral chemical burn complicated by limbal stem cell deficiency and symblepharon, which was managed by an annular conjunctival autograft from the other eye. This prospective, non-randomized, non-controlled quasi-study of 37 patients was conducted in a tertiary care eye hospital in Bangladesh from January 2015 to December 2018. Inclusion criteria were unilateral old chemical burn with total limbal stem cell deficiency and symblepharon with vision up to the perception of light. Exclusion criteria were bilateral cases, glaucoma due to a secondary cause, any pathology in the retina and optic nerve, and aqueous deficiency. All patients followed up for 24 months. The age range and mean age were 02 to 45 years and 17.14±10.92 years respectively. Fifty-four percent were at or below 16 years. Delay in presentation after burn to ophthalmologist varied from 6-156 months. Preoperative visual acuity was perception of light to 6/36 and postoperative was hand movement to 6/12. Preoperative corneal clarity defined by iris detail and pre-operatively it was clear iris detail at 2.7%, hazy iris detail at 24.3%, and no iris detail at 72.97%. Post-operatively it improved to 35.13%, 62.16%, and 2.7% respectively. Eighty-one percent of patients were happy with their post-operative outcome. In 24 months of follow up symblepharon or conjunctivalization of the cornea did not occur. Fellow eyes showed no limbal stem cell deficiency. The surgical technique of ACAU may be an option not only for the treatment of complicated old chemical burns associated with limbal stem cell deficiency and symblepharon but also can preventing it.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"810-815"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Changes of Body Mass Index, Fasting Serum Glucose and Serum Calcium in Postmenopausal Women.","authors":"N Sultana, F Wahed, A Nessa, N Khatun, S S Suchi, M Paul, S Sadia, S Yeasmin, A Begum, F R Momo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Menopause is a silent but significant event in women's life. It causes dramatic change in physical and psychological aspects. It occupies almost one third of a woman's life. This study was done to evaluate the effects of menopause and changes it brings to various physical and biochemical parameters. The aim of this study was to find out the effect of body mass index, fasting serum glucose and serum calcium levels in postmenopausal women in Mymensingh locality. This analytical type of cross-sectional study was carried out in the Department of Physiology, Mymensingh Medical College, Bangladesh from July 2023 to June 2024. A total 200 subjects were selected and from them 100 were grouped as Control group, Group I (reproductive women) and 100 were grouped as Study group, Group II (postmenopausal women). The results were calculated and analyzed by using SPSS. Anthropometric measurements such as height and weight taken in meter and kilogram respectively. Laboratory analysis of fasting serum glucose was measured by GOD-POD method and serum calcium by o-Cresolpthalein direct method. In this study it was found that body mass index, fasting serum glucose and serum calcium were altered significantly in postmenopausal women in comparison to healthy reproductive women. Fasting serum glucose was positively correlated with body mass index. Serum calcium was negatively correlated with body mass index. Therefore, by this study we recommend that routine estimation of these parameters is important for prevention of complications related to menopause.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"615-618"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Outcomes of Postpartum Eclampsia Patients admitted to the Intensive Care Unit of Tertiary Level Hospital.","authors":"U S Dina, S N Hossain, A Bushra, T Minkin, M S Rahaman, T Akter, N Zahan, A Khanom, A Shamsi, S S Shikha, S Nath, M K Jahan, K Nigar, T T Mirza","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypertensive disorders, particularly eclampsia, remain one of the leading causes of maternal mortality in our country. Postpartum eclampsia is one of the deadliest complications which may drag a mother up to Intensive Care Unit (ICU). Limited resource of critical care must be used for those patients who are most likely to get benefit. Timely recognition and treatment of the critically ill patient may improve the outcome and reduce morbidity and mortality. To find out the clinical characteristics and outcome of Postpartum eclampsia patients admitted to the intensive care unit of tertiary level hospital. It is a cross-sectional descriptive type of observational study conducted in the ICU of Mymensingh Medical College Hospital (MMCH), over a period of one year from July 2019 to June 2020. All women admitted to ICU during this period were considered for inclusion and 65 patients with diagnosis of postpartum eclampsia were selected. For each eligible patient, sociodemographic profile, indication of ICU admission, Data of ICU interventions and maternal outcome was then classified, edited, coded and entered into computer for statistical analysis by using SPSS V22.0 and presented in graph, pie chart and tabulated form. Out of 65 patients highest 25(38.46%) belonged to the age group (21-25) years and majority 52(80.0%) of patients from rural area. Most of the patients were primiparous 35(53.84%) among them 19(29.23%) patients were unbooked. Majority 48(73.84%) of patients had seizures in ≥48 hours and commonest prodromal symptom was headache 57(87.69%). Out of 65 patients, 55(84.61%) patients had vaginal delivery and 10(15.38%) patients had cesarean delivery. Commonest maternal complication was pulmonary edema 28(43.07%), 19(29.23%) patients had cerebrovascular accident, 10(15.38%) patients had HELLP syndrome, 8(12.30%) patients had Acute kidney injury, 7(10.76%) patients had MODS, 4(6.15%) had aspiration pneumonia and 2(3.07%) patients had pulmonary embolism. Most of the patients 59(90.0%) needed advance monitoring, 30(46.0%) patients received mechanical ventilation, and 27(41.0%) patients received vasoactive drugs. There were 5 maternal deaths giving rise a case fatality rate of 7.69%. Maternal mortality in present standard obstetric care is well controlled due to intensive care monitoring. Appropriate antenatal care and postnatal care are important in preventing obstetric complications.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"674-682"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross Sectional Study on Clinical Profile and Risk Factors among Ischemic and Hemorrhagic Stroke.","authors":"M A Hoque, M M Emran, M A Hanif, M M Bhuiyan, N Fatema","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The most common cause of disability disorder is stroke worldwide. Prevention is the main focus for stroke. By addressing the risk factors, stroke could be prevented. This cross-sectional observational study was conducted from September 2014 to February 2017 in the department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh. All the patients of ischemic and hemorrhagic stroke were confirmed by neuroimaging (CT scan of brain/ MRI of brain). And screening of inclusion and exclusion criteria, seventy-eight stroke patients were included in the study. Among them 60(76.0%) were ischemic (Group A) and 18(23.0%) were hemorrhagic (Group B) stroke patients. Mean age of the study population was 60.83±13.36 years and 58.58±14.77 years in Group A and Group B respectively. In both groups male was predominant. Mostly females were housewife (33.0%) and higher percentage of males was businessman (30.0%). Most of the study populations were literate in Group A but maximum of Group B were illiterate. Hypertension is the most common risk factor, then smoking, dyslipidemia, diabetes mellitus and ischemic heart disease respectively for both groups of ischemic and hemorrhagic stroke patients. Previous vascular events, family history and alcohol consumption were higher in Group A than Group B.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"771-776"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relation of Hormonal Status with Clinical Features among Patients with Polycystic Ovarian Syndrome Attending in a Tertiary Care Hospital of Bangladesh.","authors":"T Jahan, K S Rahman, N Islam, T T Mirza, S Shamsi, D Roy, N Islam, K R Hoque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Polycystic ovary syndrome (PCOS), a common and heterogeneous disorder, is characterized by oligo or anovulation, menstrual disturbances, and androgen excess. PCOS usually begins at puberty and manifested by hirsutism, obesity, insulin resistance, acanthosis nigricans, acrochordons and menstrual irregularities. Aim of the study was to assess the relation between clinical features of PCOS and different hormonal level pattern. This cross-sectional descriptive type of observational study was conducted in the Department of Obstetrics & Gynaecology and Endocrinology of Mymensingh Medical College Hospital (MMCH), Bangladesh from the period of January 2018 to December 2018. Total 108 patients were included for the study. Sample was selected by purposive non randomized sampling. Data were processed by using the Statistical Package for Social Sciences version 23.0. Ethical clearance was taken from the Institutional Review Board (IRB) of MMC. Majority (44.4%) patients belonged to age group 21-30 years with mean age was 23.8±6.2 years. Majority (57.4%) patients were married. Majority (91.7%) patients had hirsutism followed by 40(37.0%) acne, 40(37.0%) acanthosis nigricans, 16(14.8%) weight gain, sub- fertility. In this study 03(2.8%) patients were found underweight, 40(37.0%) overweight and 11(10.2%) were obese. The mean Hirsutism, Modified Ferriman Galway score was found 10.5±2.9 with range from 4 to 20. More than three fourth (75.9%) had oligo menorrhea, 20(18.5%) amenorrhea and 6(5.6%) patients had menorrhagia. Eighty (74.1%) patients had normal thyroid and 28(25.9%) had hypothyroid. Sixty (55.6%) patients were found normal HDL and 48 (44.4%) were found high HDL level. Mean serum testosterone was found 1.28±0.22 ng/ml. On USG of Pelvic Organs 27(27.0%) patients had unilateral and 73(73.0%) had bilateral PCOS (ovary) and 08(7.4%) patients had no PCOS on USG. Serum testosterone level 68(93.15%) was higher in bilateral group. Based on the findings of the study concluded that early detection of specific clinical features related to PCOS and effective screening of hormones (FSH, LH, TSH, Prolactin and Testosterone) and sonographic findings can detect the PCOS patients at early stage and thus can reduce the PCOS related symptoms and infertility.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"606-614"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}