Mymensingh medical journal : MMJ最新文献

{"title":"Deliberate Practice to Achieve Mastery of Basic Life Support Skills: Exploring the Potential of Objective Structured Clinical Examination (OSCE) As a Learning Tool.","authors":"A Motghare, P B Barde, R Kathrotia, M Naithani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ineffective performance of cardiopulmonary resuscitation (CPR) when needed will cause poor clinical outcomes. Hence more focus should be on the improvisation of CPR training. Various methods of teaching have been used in basic life support (BLS) training. This prospective, single-blinded, quasi-experimental study that evaluated an educational intervention at a tertiary teaching hospital from September 2022 to June 2023. In this study, we aimed to highlight the application of objective structured clinical examination (OSCE) to identify amateur BLS skills and the use of deliberate practice to master that skill. Structured BLS training was provided to 225 participants including nursing staff (n=158), paramedical staff (n=23) and medical students (n=44). A pre-validated OSCE checklist based on the American Heart Association (AHA) 2020 guidelines for cardiopulmonary resuscitation was included for skill-based assessment. The pre and post training OSCE scores of participants were compared. The OSCE was used to identify the skills that needed more practice and the aim was to practice until the score was 100.0% as per the OSCE checklist. A pre and post-test questionnaire with questions covering the theoretical aspects of BLS was administered to all participants. Out of 225 enrolled participants, 177 completed all stages of training. Post training OSCE scores statistically improved in all the participant with (n=79) or without prior (n=98) experience of CPR training. Most forgotten step while demonstrating the BLS was calling for help (33.0%). Immediately after training only 65.0% were able to demonstrate the BLS sequence as recommended by AHA (American Heart Association). Median number of OSCE practice sessions to achieve a 100.0% score was 2 (two) for those with prior training and 4 (four) for first-time trainees. Willingness to give CPR in future emergencies increased from 85.0% to 96.0% among participants after training. The OSCE scores pre and post training improved in both novices and previously trained participants. OSCE can be used as a training tool to check and improve knowledge of BLS.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1270-1277"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Effectiveness of Conventional Chemotherapy in Patients with Acute Myeloid Leukaemia.","authors":"S Haque, Z Z Chowdhury, N Akhter, S T Reshma, A K M Islam, M Ali, J Ferdous, M M Rahman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acute myeloid leukemia is the second most common type of leukemia in adults. The treatment of acute myeloid leukemia is very challenging. This observational study was conducted with total of 54 patients with de novo acute myeloid leukemia were identified at the department of Hematology in National Institute of Cancer Research and Hospital, Dhaka, Bangladesh from July 2016 to June 2022 who were treated with induction chemotherapy (3+7) consisting of daunorubicin and cytarabine and 3 cycles High dose intermittent ARA-Cas consolidation regimen. Patients who were refractory to induction therapy received re-induction therapy, if they achieved remission after re-induction then received consolidation therapy. Morphological complete remission was achieved in 70.4% of the patients and resistant disease was seen in 22.2% after induction therapy. Early mortality after induction therapy occurred in 7.4% cases. Thirty three percent (33.0%) of patients with complete remission after conventional therapy developed relapse with median follow up of 36 months. The median overall survival was 18 months. The overall survival of acute myeloid leukemia patients was 42.6% at 6 years. The event-free survival at a median of 36 months was 33.3%. With the view of scarcity of the indexed data in Bangladesh we have designed this study. In addition, this study result will help all hematologists.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1192-1198"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid Profile of Patients with Ischemic Stroke Involving Anterior Circulation Admitted in a Tertiary Care Hospital.","authors":"M Fakruzzaman, S M J Bhuya, M K Podder, U Sarker, M A Hosen, M R Amin, M A Kabir, M F H Hera, P D Adhikary, H B Gias, F R Momo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Stroke is a global health problem. It is the leading cause of disability and the second leading cause of mortality worldwide. This observational study was carried out in the Department of Medicine and Department of Neurology, Mymensingh Medical College Hospital, Bangladesh a tertiary-level academic and treatment-based hospital in Bangladesh from 1st July 2013 to 31st December 2013, to find out the abnormalities of lipid profile of patients of ischemic stroke involving anterior circulation. Patients having a history of stroke were enrolled in the study after getting informed written consent from the patient or attendant. One hundred hospitalized adult patients with stroke were selected for the study based on inclusion and exclusion criteria. Fifty-one percent (51.0%) of patients were accustomed to leading a sedentary lifestyle. The majority of the patients hailed from urban areas of Bangladesh and seventy-eight percent had a habit of experiencing active lifestyle patterns. Among the risk factors, it was observed that hypertension was a major (72.0% cases) risk factor for stroke. Diabetes mellitus was detected in 15.0% of cases. The majority were Type-2 Diabetes mellitus. Forty percent (40.0%) of the patients were smokers in various forms. The majority of patients (52.0%) have normal serum cholesterol within normal limits (<200 mg/dl), but in more cases 48.0% above the normal limit (>200 mg/dl), 12.0% cases have raised Low Density Lipoprotein (LDL) Cholesterol (>190 mg/dl), only 6.0% cases have low (<100 mg/dl) High Density Lipoprotein (HDL) Cholesterol and 20.0% cases have raised serum triglyceride (TG) level (>200 mg/dl). So, we should think about known dietary habits, lifestyle and risk factors of stroke, proper control of which plays an important role in the primary prevention of the disease.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"981-986"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial effect of Nigella sativa (Kalojira) against Staphylococcus aureus and Escherichia coli.","authors":"S Nasrin, S M Tusher, S Sultana, S K Paul, F Farhana, Z Adneen, M U Salma, T A Khanom","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bacterial infection is one of the biggest causes of morbidity and mortality worldwide. Pathogens have also gradually developed resistance to the miracle drug, antibiotics. That's why interest in searching for effective alternatives for the current antibiotics with different mode of action on microbes is increasing. In this regard, one of the reputed medicinal plants, Nigella sativa (Kalojira) was investigated for potential antibacterial effect against commonly encountered pathogens (Staphylococcus aureus and Escherichia coli). Both aqueous and ethanolic extract of Kalojira was found active against Staphylococcus aureus and Escherichia coli in disc diffusion method. Zone of inhibitions of aqueous extract at 100.0% (1000μg/ml) concentrations were 25mm against Staphylococcus aureus, 24mm against Escherichia coli. Zone of inhibitions of ethanolic extract were 32mm against Staphylococcus aureus and 32mm against Escherichia coli at 100.0% concentration. The broth dilution technique was performed to determine the MICs of Aqueous kalojira extract (AKE), EKE and Amikacin. The MICs of AKE were 500μg/ml and 600μg/ml against Staphylococcus aureus and Escherichia coli respectively. The MICs of EKE were 400μg/ml and 400μg/ml against aforesaid organism respectively. The MIC of Amikacin was 1.5μg/ml against Staphylococcus aureus and 1μg/ml against Escherichia coli. The MIC of Amikacin was lowest in comparison to MICs of AKE and EKE for the test organisms. The subculture study showed the same results with that of previous experiments.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1151-1156"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibody Level against Hepatitis B Virus in Term and Preterm Infants Following Three Doses of Pentavalent Vaccine as per EPI Schedule.","authors":"N Kar, M A Hossain, M N Islam, P D Adhikary, B K Saha, B Chowdhury, M Mazumder, F Fahmin, B K Banik, H Akhter, D D Adhikary, T Tazmin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Childhood acquisition of Hepatitis B infection significantly increases the risk of chronic liver disease. To prevent this, the World Health Organization (WHO) recommends immunizing infants with three doses of the pentavalent vaccine (DPT + Hib + Hepatitis B) at 6, 10 and 14 weeks of age as part of the Expanded Program on Immunization (EPI). Vaccination schedules may vary based on birth weight and maternal Hepatitis B infection status. Preterm infants, due to their potentially weaker immune status, may require revaccination or booster doses in cases of non-response or poor response. This cross-sectional comparative study was conducted in the Department of Pediatrics, Mymensingh Medical College Hospital, Bangladesh, from October 2017 to September 2019. A total of 118 infants (59 terms and 59 preterm) who had completed the three-dose pentavalent vaccine schedule were included, selected from two EPI centers in Mymensingh city. Anti-HBs antibody levels were assessed six weeks after the third vaccine dose using an ELISA immunoassay kit. The mean anti-HBs levels in preterm and term infants were 143.41±37.81 mIU/mL and 140.96±42.81 mIU/mL, respectively, with no statistically significant difference (p>0.05). A good response (anti-HBs >100 mIU/mL) was observed in 89.8% (53/59) of preterm and 86.4% (52/59) of term infants. Poor responses (anti-HBs 10-100 mIU/mL) were seen in 6.8% (4/59) of preterm and 11.9% (7/59) of term infants. Among infants with a birth weight ≥2500 gm, 87.7% (50/57) showed a good response. Infants weighing 1500-2499 g demonstrated a good response in 88.3% (53/60) of cases. Of the 53 preterm good responders, 86.8% (46) had a gestational age of ≥34 weeks at delivery. In conclusion, the current pentavalent vaccine schedule under EPI produces a good immune response in most infants, with no significant difference between term and preterm infants. Among preterm infants, a better immune response was associated with a gestational age of ≥34 weeks.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1030-1035"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Metabolic Profile and Anthropometric Measurements among Obese Children and Adolescents with Different Grades of Fatty Liver Disease: An Experience in a Tertiary Care Centre in Bangladesh.","authors":"S Mahbuba, F Mohsin, N Islam, S Jasim, S A Begum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A cross sectional study was conducted among 79 children and adolescents in Paediatric Endocrine Outpatient Department (OPD) of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, a tertiary care centre in Dhaka, Bangladesh. Children and adolescents of 8 to 18 years of age with simple obesity who visited during the period of 1st January 2018 to 30th June 2018 were included in this study. The study was done to determine the percentage of different grades of fatty liver disease and to compare metabolic profiles and anthropometric measurements among obese children and adolescents with different grades of fatty liver disease. Fatty liver disease was identified and it's grading was done by Real-time ultrasonography of hepatobiliary system. Total 24 obese children (30.4%) had fatty liver disease among 79 patients. Majority of them (54.2%) had mild fatty liver disease followed by moderate fatty liver disease (41.6%). Severe fatty liver disease was found in only one child. Fasting blood sugar (p=0.031) and SGPT level (p=0.001) were significantly higher among children and adolescents with fatty liver disease in comparison to children without it. When comparison was done in different grades of fatty liver disease, triglyceride level (p=0.033) and diastolic hypertension (p=0.016) was significantly higher in children having moderate fatty liver disease. There was no significant difference in anthropometric measurements among children having different grades of fatty liver disease.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1162-1169"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Clinical Profile and Biochemical Parameters in Diverse Phenotypes of Polycystic Ovarian Syndrome.","authors":"F Sharmin, T T Mirza, T Latif, S Shamsi, K Nigar, T Sharmin, S Akter, N S Komola, P Das, S Ferdoushi, F A Islam, H Akhter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Polycystic ovary syndrome (PCOS) is a polygenic and multifactorial condition, considered as the most common endocrine problem of women in reproductive age. Insulin resistance, hyper-androgenism and obesity significantly influence the pathophysiological process of PCOS. This study was designed to estimate clinical and biochemical parameters in different phenotypes of PCOS. The cross sectional descriptive type of observational study was carried out at Mymensingh Medical College Hospital, Bangladesh from January 2018 to June 2019 among purposively selected 107 patients with PCOS. Data were analyzed by computer software, SPSS, version 22.0. Quantitative variables of this study were summarized using mean and standard deviation and qualitative variables were summarized by percentage. Biochemical parameters in different phenotypes were compared with t-test. Phenotype A was found in highest number (59.8%) followed by phenotype B (14.9%), phenotype D (14.0%) and phenotype C (11.2%). Biochemical hyper-androgenism was observed highest in phenotype A (57.8%) followed by phenotype B (36.4%) and phenotype C (6.1%). Biochemical or clinical hyper-androgenism was not observed among patients of phenotype D. Mean age of phenotype A, B, C and D were 22.92±6.36, 20.81±3.69, 24.82±5.96 and 21.94±4.12 years respectively. All the phenotypic subgroups were found higher in the high and middle class urban family. Body mass index (BMI), waist circumference and waist hip ratio were increased in all phenotypes but more in phenotype A and B. Blood pressure had no significant change. Phenotype A presented with oligo-menorrhea (50.47%), amenorrhea (7.48%) and menorrhagia (1.87%). Majority of phenotype B (13.08%) and D (12.15%) presented with oligo-menorrhea. All the phenotype C (11.2%) had normal menstrual cycle. Hirsutism was more in phenotype A and B. Phenotype A presented with more severe acne (19.6%), acanthosis nigricans (38.3%), weight gain (34.6%) and subfertility (18.7%) than others. Phenotype A and B had high serum total cholesterol and triglyceride but low serum HDL. Phenotypic division helps in better understanding the pathophysiology of PCOS, severity of the disease and also helps in predicting the adverse effects. Moreover, identifying various phenotypes have diagnostic implications and also assist in providing appropriate treatment and prognosticating the patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1010-1019"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Acute Stroke and Glycemic Abnormalities with Stroke Outcome: A Hospital Based Study.","authors":"H K Roy, M A Rouf, M R Karim, H Pandit, M R Haidar, M A Hoque, T Akter, M S Hussain, M Islam, M S A Mozahid, P D Adhikary, M S Ahsan, M S Nahyan, M A Mural","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Stroke is a major health burden and a leading cause of morbidity and mortality. Acute stroke is stressful event and patients suffering from an acute stress such as stroke or myocardial infarction may develop hyperglycemia, even in the absence of a preexisting diabetes mellitus. This cross sectional observational study was conducted in the Department of Medicine and Neuromedicine, Mymensingh Medical College Hospital, Bangladesh from 16th August 2020 to 15th February 2021 to evaluate the glycaemic status in first ever ischaemic stroke patient admitted within 24 hours in a tertiary care hospital. Data were collected from the patients or informant and recorded in structured case record form. Thorough clinical examination and relevant investigation were done. SPSS and Microsoft excel were used for data analysis and processing. On assessment of glycaemic status, 71.0% of patients were found to have blood sugar level ≤7.7 mmol/L where 29.0% patients were blood sugar level ≥7.8mmol/L. This study demonstrated that, prevalence of acute stress hyperglycemia in stroke patient is detected 29.0% in tertiary centre hospital of Bangladesh. Evaluation was done on the basis of patient's symptoms, degree of disability or dependence in the daily activities and clinical outcome and it was measured by modified Rankin Scale (MRS). Study shows that 81.0% of the patients recovered (MRS score 0 to 2), among them maximum were normo-glycemics patients (90.1% vs. 51.7%). Fourteen patients developed poor outcome, they were disabled and discharged on request or risk bond (MRS score 3 to 5). In this study 7.0% expired during hospital stay (MRS score 6). In expired case maximum were stress hyper-glycemics patients (2.8% vs. 17.2%). So, in-hospital outcome is very poor in stress hyper-glycemics patients. We investigated association between acute stroke and glycaemic abnormalities, and found that stroke or other vascular event is harbor, or risk factor for prediabetes and diabetes. Proper evaluation, prevention of risk factor, and strict glycemic control is suggested for prevention of complication and reduction of occurrence of such event.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"963-973"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude and Practice about Covid-19 among the Adult Population of a Sub-urban Community in Bangladesh.","authors":"M M Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Covid-19 is a major public health concern globally and also in Bangladesh. The highly transmissible Covid-19 has plagued the worldwide population with a continuous upward thrust of the death toll, which might be related to insufficient knowledge, attitude and practice (KAP) score, and public awareness. The study was carried out with the objective to assess the level of knowledge, attitude and practice regarding Covid-19 among the adult people of a selected sub-urban community. It was a descriptive type of observational study that was carried out at Keraniganj Upazilla, Dhaka, Bangladesh from August 2022 to October 2022. Data were collected by face to face interview with a semi-structured questionnaire. Total 618 adult persons were included in the study. Total 15 questions were asked to assess the knowledge, attitude and practice of Covid-19. It is found that, majority 423(68.4%) of the respondents have the correct knowledge about the causative agent, 479(77.5%) of the respondents have the correct knowledge about the mode of transmission, 466(75.4%) of the respondents have the correct knowledge about the source, 528(85.4%) of the respondents have the correct knowledge about the symptoms of the disease 564(91.3%) of the respondents have the correct knowledge about preventive measures. Regarding attitude, majority 297(48.1%) of the respondents feel that Covid-19 is a very dangerous disease, 341(55.2%) respondents believe that vaccines are very useful, 351(56.8%) respondents believe that mask is very useful, 336(54.4%) respondents believe that distancing and isolation is very useful and 553(89.5%) respondents have the positive attitude about treatment seeking. Regarding practice, it is revealed that, only 25(4.0%) of the respondents are not vaccinated against Covid-19; 268(43.4%) respondents have taken 3 doses, 286(46.3%) respondents have taken 2 doses and 39(6.3%) respondents have taken 1 dose of vaccine. It is also found that, 321(51.9%) respondents use face mask irregularly, 364(58.9%) respondents wash hands regularly and 328(53.1%) respondents maintain distance sometimes. The findings of the study indicate that knowledge regarding Covid-19 is very poor among the community people. Considering the findings of the study it is recommended that more emphasis should be given on awareness building programs to attain positive attitude and proper practice related to Covid-19.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1177-1184"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Vitamin D Deficiency among Obese and Normal Children of Bangladesh.","authors":"A Z Tanni, T Haq, M Mustari, S Selim, R Sarkar, M Shahed-Morshed, M A Hasanat, M Fariduddin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Obesity is a risk factor for vitamin D deficiency (VDD) with limited data on their association with Bangladeshi children. The aim of this study was to compare vitamin D levels and the status among obese, overweight and normal-weight children. This cross-sectional study was performed in the Obesity Clinic, Department of Endocrinology, Bangladesh Medical University hospital, Bangladesh from May 2020 to August 2021 and included 100 children of 10-17 years [age-matched 50 children with normal BMI, 22 with overweight and 28 with obesity: 14.0 (12.0-17.0) vs. 12.50 (10.0-16.25) vs. 12.50 (11.0-14.0), years, median (IQR), p=0.114] of both sexes (boys/girls: 49/51). Height and weight were measured to calculate body mass index (BMI) and plotted in the Centre for Disease Control chart to classify normal, overweight and obese with cut-offs of 85th and 95th BMI-percentile. Serum 25-hydroxy vitamin D[25(OH)D] was measured by chemiluminescent microparticle immunoassay. VDD (<20 ng/mL) and insufficiency (20-29.9ng/mL) were found in 92 and eight patients respectively with none having sufficiency (≥30 ng/ml). Among 92 patients with VDD, 61 (66.30%) had mild VDD (10-19.9 ng/mL) and 31 (33.70%) had moderate to severe VDD (<10 ng/mL). Vitamin D level and status were statistically similar across BMI-spectrum (NS for all). Vitamin D level did not significantly correlate with BMI (r=-0.026, p=0.798). Children with moderate to severe VDD had significantly higher percent of girls (67.7% vs. 44.3%, p=0.047), living in urban area (100.0% vs. 85.2%, p=0.026) with higher socio-economic status (61.3% vs. 32.8%, p=0.023) than those with mild VDD. In conclusion, despite high percentages of VDD, vitamin D had no association with BMI in children.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1095-1102"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}