Mymensingh medical journal : MMJ最新文献

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Comparison between Combination of Neem, Propylene Glycol and Salicylic Acid with Salicylic Acid Alone Topically in Arsenical Palmar Keratosis. 印楝、丙二醇、水杨酸联合与单用水杨酸治疗砷性掌角化病的比较。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
K Sabiha, M Misbahuddin, A S M Chowdhury
{"title":"Comparison between Combination of Neem, Propylene Glycol and Salicylic Acid with Salicylic Acid Alone Topically in Arsenical Palmar Keratosis.","authors":"K Sabiha, M Misbahuddin, A S M Chowdhury","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Arsenicosis, a problem with chronic ingestion of arsenic in drinking water was first detected in 1993 in Bangladesh. Currently, 61 districts have been identified as having an arsenic concentration exceeding the maximum permissible limit of 0.05 mg/L. More than 40,000 people developed signs and symptoms of arsenicosis, manifested as skin hyperpigmentation often with hypopigmentation and later painful Keratosis on the palm and sole with fissures, cracks and warty lesions that reduce the working ability of patients. Keratosis is difficult to cure for its longer duration treatment and standard treatment is still lacking. Neem (Azadirachta Indica), a valuable source of unique natural products, has been used in various conditions, including skin care. Topical use of ethanol extract of neem has also been found to be effective. A cost-effective topical drug, in lower concentration with shorter duration and less adverse effect, is necessary. The purpose of this study was to observe the effect of the combination of neem, propylene glycol and salicylic acid for the treatment of palmar arsenical keratosis. Thirty patients of moderate palmar arsenical keratosis from an arsenic-affected area at Cumilla in Bangladesh were recruited randomly based on inclusion and exclusion criteria. One group of patients was given salicylic acid (10.0%) lotion in ethanol and another group of patients was given a combination of ethanol extract of neem (10.0%), propylene glycol (40.0%) and salicylic acid (10.0%). Clinical improvement was assessed by measurement of the palmar arsenical nodular size of both hands by slide calipers before and after the completion of treatment and perceptions of the patients about their improvement was scaled. The score (mean±SD) of the nodule of patients using neem (10.0%) plus propylene glycol (40.0%) plus salicylic acid (10.0%) before the study was 19.6±10.2 which was decreased to 8.1±6.6 after treatment. After 12 weeks of treatment, the mean perception score of improvement in neem (10%) plus propylene glycol (40.0%) plus salicylic acid (10.0%) was 4.8±0.6, improved from 2.2±1.1 in salicylic acid (10.0%) alone group. None of the patients reported any side effects rather topical use of a combination of ethanol extract of neem plus propylene glycol plus salicylic acid showed a significant effect in improving the keratotic lesion.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"728-737"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated Intravascular Coagulation in Children: An Update. 儿童弥散性血管内凝血:最新进展。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
N Kamal, M M Hossain
{"title":"Disseminated Intravascular Coagulation in Children: An Update.","authors":"N Kamal, M M Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Disseminated Intravascular Coagulation (DIC) is a complex syndrome causing generalized micro thrombi formation, which causes consumption of coagulation factors resulting in secondary fibrinolysis. It is not uncommon in children. Due to its highly complex and variable pathophysiology and interrelationship with hemostatic system, DIC does not show any uniformity in presentation. Although, there are many forms of DIC, clinical picture of DIC is dominant with bleeding. Besides, there is no gold standard investigation to diagnose DIC. Many therapeutic approaches are not validated and controversial. Prompt diagnosis and correct treatment depends on understanding of underlying pathology. Treatment should be individualized depending on the nature of DIC to correct the underlying pathology, as complexity and variation of presentation suggests.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"942-949"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Post-Operative Outcomes in Closure and Non-Closure of Peritoneum in Open Appendicectomy for Uncomplicated Appendicitis. 无并发症阑尾炎开放性阑尾切除术中闭合与不闭合腹膜的早期术后疗效。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
F F Kollol, M A Uddin, M M Hossain, K R Hoque, M A Shakil, A H M Sufiyan, N Biswas, N Islam, S M S Hasan, I Jahan, M Mashruh, M A Anon, M W Islam, T R Shanta, M A A Mamun, M A Baten, M A K Azad
{"title":"Early Post-Operative Outcomes in Closure and Non-Closure of Peritoneum in Open Appendicectomy for Uncomplicated Appendicitis.","authors":"F F Kollol, M A Uddin, M M Hossain, K R Hoque, M A Shakil, A H M Sufiyan, N Biswas, N Islam, S M S Hasan, I Jahan, M Mashruh, M A Anon, M W Islam, T R Shanta, M A A Mamun, M A Baten, M A K Azad","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Open appendicectomy remains a common surgical procedure for managing uncomplicated acute appendicitis. Traditionally, peritoneal closure has been performed to restore anatomical layers, but this practice has been questioned due to its potential impact on surgical duration, postoperative pain and recovery outcomes. This study aims to compare early postoperative outcomes between peritoneal closure and non-closure techniques in patients undergoing open appendicectomy. This prospective comparative study was conducted at Mymensingh Medical College Hospital, Bangladesh, from July 2021 to June 2022, including 80 patients undergoing open appendicectomy for uncomplicated acute appendicitis. Patients were divided into Group I (peritoneal closure) and Group II (peritoneal non-closure).Data were processed and analyzed using the computer software SPSS (Statistical Package for Social Sciences, version 26.0 for Windows). The probability value, p<0.05 was considered statistically significant. There was no significant difference in age, sex, BMI, or comorbidities between the groups. Most procedures used a Grid Iron incision (67.5%). Wound infection (22.5%, 17.5% respectively) and wound dehiscence (7.5%, 2.5% respectively) rates were almost similar, with no significant differences (p=0.576 and p=0.305, respectively). However, Group II had significantly lower postoperative wound pain (p<0.001), reduced analgesic requirements (p<0.001) and shorter surgery duration (p<0.001) compared to Group I, demonstrating the potential benefits of omitting peritoneal closure in appendicectomy. It is concluded that non-closure of the peritoneum at open appendicectomy for uncomplicated appendicitis appears to have no adverse effect on post-operative recovery and outcome. Leaving the peritoneum open seems to reduce the operating time and shorter hospital stays. It also decreases post-operative pain with less analgesic requirement. Hence, the practice of non-closure of peritoneum in open appendicectomy for uncomplicated appendicitis can be done safely.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"707-713"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Leiomyoma of Ovary: A Case Report. 卵巢原发性平滑肌瘤1例报告。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
S Jahan, K N Maya, M Akanda, I Jahan, J Morshed
{"title":"Primary Leiomyoma of Ovary: A Case Report.","authors":"S Jahan, K N Maya, M Akanda, I Jahan, J Morshed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Leiomyoma is the most common benign mesenchymal tumor of the uterus and it can develop in any location containing smooth muscle cells. While the broad ligament is the most frequent extrauterine site, the ovary is among the rarest, representing only 0.5-1.0% of all benign ovarian tumors. Primary ovarian leiomyoma is a benign ovarian tumor that typically occurs in women aged 20 to 65. It is often discovered incidentally during pelvic examinations, ultrasound imaging, or through pathological analysis following surgery. We are reporting a case of a 38-years-old woman who presented with a history of lower abdominal pain in left side. Ultrasonography of whole abdomen revealed a left adnexal mass. Unilateral salpingo-oophorectomy was performed. Ovarian leiomyoma was diagnosed after surgery followed by histopathologic examination and confirmed by immunohistochemistry.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"932-935"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical and Functional Outcome Following Surgery of Idiopathic Macular Hole. 特发性黄斑裂孔手术后的解剖和功能结果。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
S M F Hasan, P K Roy, F Aminul, M Abdullah, M A Islam, M A H Akhanda
{"title":"Anatomical and Functional Outcome Following Surgery of Idiopathic Macular Hole.","authors":"S M F Hasan, P K Roy, F Aminul, M Abdullah, M A Islam, M A H Akhanda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Macular hole is a full thickness defect at the centre of macula. Pars plana vitrectomy with internal limiting membrane (ILM) peeling and gas tamponade helps to close the hole and improves visual function. Aim of this study was to assess the anatomical and functional outcome following surgery of idiopathic macular hole. This interventional study was conducted in the Department of Vitreo retina, National institute of ophthalmology and hospital, Dhaka from December 2020 to August 2022. A total, 50 patients having idiopathic macular hole were included during the study period according to selection criteria. Preoperative logarithm of minimal angle of resolution (logMAR) visual acuity was measured and Optical Coherence Tomography (OCT) was done for further staging of hole. Pars plana vitrectomy, ILM peeling assisted with Brilliant blue G dye and perfluoropropane gas tamponade was done under local anesthesia. Patients were instructed to maintain a facedown position for two weeks. Postoperatively, patients were examined on day one, day seven, after one and three months. At each follow up visual acuity, ocular examination and measurement of intraocular pressure was done. OCT was done to assess anatomical closure of hole and final visual outcome was measured as best corrected visual acuity (BCVA) at three months after surgery. After data collection data were coded, entered and analyzed in a computer. Statistical test was done by windows software using statistical package for social science (SPSS) statistics for Windows, Version 26.0. Male female ratio was 1:2.3. Among 50 patients, majority (29; 58.0%) were in stage II macular hole. Duration of symptoms was more than five months before surgery in 35(70.0%) patients. Majority of study patients (82.0%) were phakic. Preoperative BCVA was found as 1.48-1.00 logMAR in 33(66.0%) patients. BCVA (0.94±0.13 vs. 0.62±0.26 in logMAR) was significantly (p<0.001) improved after macular hole surgery. Macular hole was closed in majority (45; 90%) of the study patients. Preoperative BCVA and stage of macular hole were significant factors for visual improvement. This study revealed that the overall closure rate of macular hole was satisfactory and BCVA was significantly improved during the last follow up.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"881-886"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Risk Factors for Infants Born with Congenital Renal and Urinary Tract (CAKUT) Anomalies: A Cross-Sectional Assessment. 出生时患有先天性肾和尿路(CAKUT)异常的婴儿的母亲危险因素:横断面评估。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
N Akand, P K Sarkar, M J Alam, M Rahman, T Tabassum, B Chowdhury, M Hanif
{"title":"Maternal Risk Factors for Infants Born with Congenital Renal and Urinary Tract (CAKUT) Anomalies: A Cross-Sectional Assessment.","authors":"N Akand, P K Sarkar, M J Alam, M Rahman, T Tabassum, B Chowdhury, M Hanif","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) often results in renal failure. Alhough the pathophysiology of CAKUT is still not completely understood, several maternal risk factors have been identified associated with children with CAKUT so far. Therefore, the aim of this study was to assess the proportion of risk factors of mothers gave birth to the infants with CAKUT. This cross-sectional study was conducted over a six-month period in the Departments of Pediatrics, Pediatric Nephrology, Neonatology and Pediatric Urology in Dhaka Shishu Hospital, Bangladesh from May 2018 to November 2018. A total of 200 infants aged ≤60 days and with a confirmed diagnosis of CAKUT were included in this study. Informed ascend was taken from the parents of the child. A semi-structured questionnaire was used for data collection, and statistical analysis was performed using SPSS version 21.0. This research was undertaken in conjunction with the ethical principles of Declaration of Helsinki. The mean age of the infants with CAKUT was 22.25±15.08 (SD) days with a male to female ratio of 1:1. The presenting anomalies were primary vesico-ureteral reflux (38.0%), pelvi-ureteric junction obstruction (20.0%), agenesis of the kidney (16.0%), posterior urethral valve (12.0%), dysplasia of the kidney (10.0%) and multicystic dysplastic kidney (3.5%). The most common pregestational risk factors were overweight (76.0%), diabetes mellitus (32.5%) and hypertension (29.5%) among the mothers. On the other hand, oligohydramnios (87.5%), gestational diabetes mellitus (67.0%) and gestational hypertension (45.5%) were the most frequently identified gestational risk factors. Pregestational overweight in women, maternal diabetes and oligohydramnios were most commonly identified risk factors among the mothers of CAKUT infant.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"874-880"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mononeuritis Multiplex as an Initial Presentation of Rheumatoid Arthritis: A Rare Case Report from Bangladesh. 多发性单神经炎作为类风湿关节炎的初始表现:来自孟加拉国的一例罕见病例报告。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
M A K Azad, S S Sunny, M M Haque, R Alam, M M Rahman
{"title":"Mononeuritis Multiplex as an Initial Presentation of Rheumatoid Arthritis: A Rare Case Report from Bangladesh.","authors":"M A K Azad, S S Sunny, M M Haque, R Alam, M M Rahman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rheumatoid vasculitis (RV) is an uncommon extra-articular manifestation of Rheumatoid Arthritis (RA) that typically affects patients with a more aggressive form of the disease. The diagnosis of rheumatoid vasculitis is suggested based on clinical presentation, laboratory findings, and confirmed through biopsy. We describe the case of a 28-year-old man who initially presented with myalgia and weakness in all four limbs. Subsequently, he developed hypertension and testicular tenderness. Neurological examination revealed painful sensory-motor neuropathy involving the bilateral median and ulnar nerves, as well as the right tibial and left common peroneal nerves- findings consistent with mononeuritis multiplex. Laboratory investigations showed a high titer of rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies. He was treated with intravenous methylprednisolone (1 gm daily for 3 days), followed by oral prednisolone (1 mg/kg body weight) and six pulses of intravenous cyclophosphamide. This was later transitioned to maintenance therapy with azathioprine. The patient showed dramatic clinical improvement, and at one-and-a-half-year follow-up, he remained reasonably well. This case highlights that mononeuritis multiplex due to rheumatoid vasculitis can be the initial presentation of Rheumatoid Arthritis. Clinicians should consider this diagnosis in similar clinical scenarios, and prompt immunosuppressive treatment should be initiated to prevent further complications.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"936-941"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Study of Appendicitis in Preschool and School-Age Children: Clinical Features and Outcomes. 学龄前和学龄儿童阑尾炎的临床特征和预后比较研究。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
M S Ali, M A A Mahmud, S Islam, M S Bari, M A Baten, M A Al Mamun, R N Karmaker, M B Hossain, M Mokarabin
{"title":"Comparative Study of Appendicitis in Preschool and School-Age Children: Clinical Features and Outcomes.","authors":"M S Ali, M A A Mahmud, S Islam, M S Bari, M A Baten, M A Al Mamun, R N Karmaker, M B Hossain, M Mokarabin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Appendicitis is one of the most common causes of abdominal pain requiring surgical intervention in children. This study aims to compare the clinical features, diagnostic accuracy, and outcomes of appendicitis in preschool-aged and school-aged children using the Pediatric Appendicitis Score (PAS) and Alvarado Score. This prospective comparative study was conducted in the Department of Pediatric Surgery, Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2023 to July 2024, including 386 children diagnosed with appendicitis. The cohort consisted of 86 preschool-aged children (<6 years) and 300 school-aged children (6-14 years). Clinical presentation, diagnostic scores (PAS and Alvarado), and outcomes were analyzed. Preschool-aged children presented with delayed diagnosis and more severe clinical features, including higher rates of perforation (58.0%) compared to school-aged children (32.0%). The mean PAS and Alvarado scores were lower in preschool children, leading to challenges in early recognition. In contrast, school-aged children demonstrated more consistent symptomatology, allowing for earlier diagnosis and intervention. Despite similar management protocols, preschool children experienced higher complication rates and longer hospital stays (mean: 7.2 days) compared to school-aged children (mean: 4.5 days). Preschool-aged children are more vulnerable to severe appendicitis due to delayed diagnosis and atypical presentations. This study highlights the need for heightened clinical suspicion and the potential refinement of diagnostic scoring systems to improve early detection and outcomes in younger children.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"660-665"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Vitamin B12 Level in Patients with Type 2 Diabetes Mellitus on Metformin Therapy and its Impact on Peripheral Nerve Conduction: A Prospective Study. 二甲双胍治疗2型糖尿病患者血清维生素B12水平及其对周围神经传导的影响:一项前瞻性研究
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
S L Wakode, A Singhai, R Gour, A E Thakare, S M Hulke, R Bharshankar, N S Wakode
{"title":"Serum Vitamin B12 Level in Patients with Type 2 Diabetes Mellitus on Metformin Therapy and its Impact on Peripheral Nerve Conduction: A Prospective Study.","authors":"S L Wakode, A Singhai, R Gour, A E Thakare, S M Hulke, R Bharshankar, N S Wakode","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Metformin is the primary treatment for newly diagnosed T2DM patients. However, Metformin may cause Vitamin B12 deficiency, which may either cause neuropathy or indirectly worsen hyperglycemia-induced neuropathy. Aims of the study was to record the effect of six months of regular metformin therapy on vitamin B12 level and to study the impact of Vitamin 12 on peripheral nerve conduction in response to 6 months of metformin therapy. This was a longitudinal study done in the Department of Physiology in collaboration with the Medicine Department of AIIMS, Bhopal, on 52 newly diagnosed cases of diabetes mellitus. A nerve conduction study was done at the start and at the end of six months using the Nihon Kohden Neuropack X1 Machine. Serum B12, homocysteine (HC), Methyl Malonic acid (MMA), RBS and HbA1c were estimated at the start and at the end of six months. The study involved 52 participants in the range of 38.8-49.0 years (Median- 45 years). Six months of metformin therapy significantly affected Vitamin B12 (decrease), serum HC (increase) and serum MMA levels (increase) (p<0.001). A significant decrease in amplitude and nerve conduction velocity was observed in the motor and sensory nerve conduction study. Significant correlations were seen between Vitamin B12 levels and a number of nerves affected, Serum MMA and Serum HC levels. Six months of metformin therapy had a significant effect on decreasing the level of vitamin B12. No new patient developed neuropathy; however significant decrease in amplitude in motor as well as sensory nerve conduction study was observed which may be due to significant decrement in B12 level. However, further studies are recommended in diabetic patients with large sample sizes and varied durations.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"904-913"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Profile and Outcome of Intercostal Tube Drainage in Patients with Secondary Spontaneous Pneumothorax. 肋间管引流治疗继发性自发性气胸的临床特点及疗效。
Mymensingh medical journal : MMJ Pub Date : 2025-07-01
M D J Khan, M A Islam, K R Hoque, M A Rahman, M S Sorwer, M A Islam, T B B Disha, M A H Miah, N Islam, K R Hoque, M A Rouf, A B Kamrul-Hasan
{"title":"Clinical Profile and Outcome of Intercostal Tube Drainage in Patients with Secondary Spontaneous Pneumothorax.","authors":"M D J Khan, M A Islam, K R Hoque, M A Rahman, M S Sorwer, M A Islam, T B B Disha, M A H Miah, N Islam, K R Hoque, M A Rouf, A B Kamrul-Hasan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pneumothorax is a prevalent pleural condition encountered by physicians in clinical practice, classified into two types: primary spontaneous pneumothorax (PSP) and secondary spontaneous pneumothorax (SSP), with SSP being more common, which necessitates prompt intervention due to its poorer prognosis and reduced likelihood of successful conservative management. The primary objective of this study is to assess the outcome of intercostal tube drainage in individuals with secondary spontaneous pneumothorax. The study took place in Mymensingh Medical College Hospital, a leading tertiary care hospital in Bangladesh. The research involved 175 patients selected through a purposive non-probability sampling technique. Among 175 patients, remarkably, 161 patients (92.0%) reported experiencing relief from dyspnea, while 147(84.0%) exhibited an expansion of lung fields. This suggests that patients who find relief from dyspnea are likely to experience lung field expansion. This data highlights the substantial correlation between these two clinical outcomes in this patient population. Postoperative pain (49.0%) was the most prevalent consequence, and tube dislodgement (2.0%) was the least common complication after Intercostal tube insertion. Regarding the duration of hospital stays, 84 patients (48.0%) were discharged within 7 days, 56 patients (32.0%) were hospitalized for 8-14 days and 35 patients (20.0%) remained in the hospital for more than 14 days. In comparison, the durations for intercostal tube insertions were 0-7 days for 105 patients (60.0%), 8-14 days for 35 patients (20.0%) and over 14 days for another 35 patients (20.0%).</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"650-655"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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