Mymensingh medical journal : MMJ最新文献

{"title":"Association of Depressive Symptoms with Glycemic Control and Diabetic Complications in Patients with Type 2 Diabetes Mellitus: A Facility-Based Cross-Sectional Study in Bangladesh.","authors":"M S Hossain, K Hassan, R Laboni, S M Ashrafuzzaman, M Tabassum, M A Rafi, M J Hasan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Comorbid depressive symptoms in diabetic patients may be associated with metabolic deterioration. The objective of this facility-based cross-sectional study was to determine the prevalence of depressive symptoms and their association with glycemic control and diabetic complications among patients with type 2 diabetes mellitus (T2DM) in Bangladesh. This study was conducted among 350 patients with type 2 diabetes mellitus attending the outpatient department of the Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka Bangladesh, from July 1, 2021 to July 31, 2021. The prevalence of depressive symptoms was 31.0% (mild 10.0%, moderate 12.0%, moderately severe 5.1% and severe 4.0%). In the logistic regression model, age (aOR 1.11, 95% CI 1.01-1.22), female sex (aOR 2.47, 95% CI 1.22-5.00), rural residence (aOR 3.42, 95% CI 1.82-6.45), single living (aOR 7.34, 95% CI 5.51-9.63), poor glycemic control (aOR 2.59, 95% CI 1.31-5.12) and cardiovascular complications (aOR 4.17, 95% CI 1.36-12.78) were independent predictors of depressive symptoms among T2DM patients. The findings observed from this study support an association between depressive symptoms and poor glycemic control as well as cardiovascular complications of diabetes.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1125-1132"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etiology and Antibiotic Sensitivity Pattern of Bloodstream Infection in Patients with Hematological Malignancy Having Febrile Neutropenia.","authors":"M N Karim, M A Khan, M H Rahman, T Ara, M Akther, H Nazneen, M K Pramanik, M M Ahmed, T Tabassum, A Rafi, M J Hasan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Febrile neutropenia (FN) is a common clinical consequence of chemotherapy in patients with hematological malignancies which make them vulnerable to bloodstream infection (BSI) due to profound immunosuppression. The objective of the present study was to explore the etiology and antibiotic sensitivity pattern of causative organisms of BSI in these patients. This cross-sectional study was conducted in Hematology department of Dhaka Medical College Hospital, Dhaka, Bangladesh from July 2020 to June 2021; including 99 adult patients with hematological malignancies who developed febrile neutropenia after receiving chemotherapy. Blood culture and antibiogram were done for isolation and investigation of antibiotic sensitivity pattern of the causative organisms. Total of 33.0% blood sample yielded a positive culture. Escherichia coli was the most common Gram negative bacteria (22.0%) followed by Klebsilella (15.6%) and Enterococci and Staphylococcus was the most common Gram-positive bacteria. Almost 33.0% of the isolated bacteria were multi-drug resistant (Gram-positive 38.0% and Gram-negative 22.0%). Among the antibiotics, carbapenem group of antibiotics like meropenem and imipenem, along with gentamycin and ticoplanin, linezolid and nitrofurantoin were found as sensitive in a substantial number of gran-positive and gram-negative bacteria. Bloodstream infection is common in patients with chemotherapy induced FN for hematological malignancies and widespread resistance to common antibiotics has made its treatment challenging. Appropriate antibiotic therapy based on local evidence and culture and sensitivity test is crucial for optimum management of these patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1170-1176"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude and Practice about Hepatitis C Virus Infection among the Health Care Workers in a Tertiary Care Hospital of Bangladesh.","authors":"M A Hossain, M K Alam, M M Rahman, S M Ashrafozzaman, F Ahamed, S Bhuiyan, M A Islam, P R Das, D Bhat, M R Karim, M Shahidullah, M Junaid, M M Moshwan, M A Hoque, M R Haidar, M A Rouf, M A Mural","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hepatitis C Virus (HCV) is emerging as one of the major health problems in Bangladesh. Worldwide, there are roughly 71 million people who are chronically infected. Prevalence of HCV infection in Bangladesh is 0.88%. Chronic HCV carriers have the potential of transmitting HCV parenterally in the hospital setting; thus, health care workers (HCWs) are at risk of contracting HCV, with the most likely exposure being via a needle stick injury (NSI). As there is no effective vaccine till today, personal protection, safe transfusion of blood and blood products, safe disposal of Hospital bio-waste and use of disposable or auto-disabled syringes would be the best preventive option for a country like Bangladesh. This study aimed to investigate the knowledge, attitudes and practices regarding hepatitis C virus among health care workers in Mymensingh Medical College Hospital (MMCH). This cross-sectional observational study was conducted among 239 health care workers (79 Doctors, 100 Nurses, 50 Lab technicians and 10 Porters) from July 2019 to December 2019. Data were collected by structured questionnaire. The overall response rate was 85.0%. For knowledge about hepatitis C virus physicians were the most knowledgeable while porters are least knowledgeable group. Males who were over 40 years old and had working history of more than 10 years were most likely to show positive attitude towards hepatitis C. Physicians have more positive attitude than other groups. Those who received training had more positive attitude than others. In this study about half of participant took training about standard precaution. Though about fifty percent participant knows about protective measures but not all of them used it. Measures taken against blood borne viruses specially against hepatitis C virus are not satisfactory among the health care staffs of MMCH, Bangladesh. Therefore, a guideline should be put in place and implemented by the government and private health care authorities.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"974-980"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Morbidity and Mortality of Neonatal Intestinal Obstruction.","authors":"A H M Sufian, S Bari, N A Sheuli, A K M Islam, M M Hossain, M M H Rahman, F F Kollol, M Mashruh, S M A Haque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neonatal intestinal obstruction (NIO) is a critical surgical emergency with high morbidity and mortality, particularly in resource-limited settings. This study aims to evaluate the predictors, treatment modalities, and outcomes of NIO in neonates admitted to a tertiary care hospital in Bangladesh. This cross-sectional observational study was conducted at the Department of Pediatric Surgery, Mymensingh Medical College Hospital, Bangladesh, from July 2017 to October 2018. Data were collected from 60 neonates diagnosed with NIO through detailed clinical evaluations, laboratory investigations and imaging studies. Treatment modalities included surgical interventions and conservative management, with outcomes analyzed using descriptive and inferential statistics. The majority of neonates (71.67%) were aged between 2-5 days, with a male predominance (66.67%). Anorectal malformation (45%) and Hirschsprung's disease (26.67%) were the most common causes of NIO. Surgical interventions were predominant, with pelvic colostomy (26.67%) and anoplasty (18.33%) being the most frequently performed procedures. Morbidity was observed in 71.67% of cases, while mortality occurred in 23.33%. Low birth weight (p<0.05), delayed presentation (p<0.05), elevated C-reactive protein (CRP) levels (p<0.05), and sepsis (p<0.05) were significantly associated with mortality. Early treatment (within 72 hours) showed a trend toward better survival, though not statistically significant (p>0.05). The study highlights low birth weight, delayed presentation, sepsis and elevated CRP levels as key predictors of adverse outcomes in neonates with NIO. Timely diagnosis, early intervention, and improved perioperative care are essential to reduce morbidity and mortality. Regional healthcare improvements are crucial for optimizing neonatal outcomes in resource-limited settings.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"991-999"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Disseminated Intravascular Coagulation in Children with Acute Lymphoblastic Leukemia during Induction Chemotherapy in A Tertiary Care Hospital.","authors":"S Akhter, M A Karim, U N Ara, P Mahtab, A Nahar, T Chowdhury, F M Monika, M A T Rahman, F A Mou, S Nahar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The overall cure rate for childhood acute lymphoblastic leukemia (ALL) has improved from virtually zero to the current event-free survival rate (EFS) of more than 90.0%. Disseminated intravascular coagulation is the commonest hemostatic abnormality in patients with ALL. It might cause serious hemorrhagic complications and warrants proper medical attention in due time. To detect the frequency, identify the risk factors and outcome of disseminated intravascular coagulation in children with acute lymphoblastic leukemia during induction chemotherapy. This prospective observational study was carried out in 55 diagnosed cases of ALL children in the department of pediatric hematology and oncology, BSMMU from November 2020 to October 2021. Patients were on regular follow-up with special attention to bleeding manifestation, fever, diarrhea, respiratory distress. DIC was detected by using the International Society of Thrombosis and Haemostasis scoring system by using Prothrombin time, Platelet count, Serum fibrinogen and D-dimer. Investigation for diagnostic DIC evaluation was done on every patient at baseline, on day 7, day 14 and day 21. Statistical analysis of the results was obtained by using windows computer software with Statistical Packages for Social Sciences (SPSS-version 22.0). Out of 55 patients, DIC was encountered in 12(21.8%) patients. At diagnosis, DIC was found in 8 patients (14.54%), on day 7, DIC was found in 4 patients (8.0%). A total of 8(14.54%) patients have developed DIC at diagnosis, among them 4(50.0%) had persisted DIC after starting chemotherapy, 4 patients resolved. But 4 patients (8.5%) newly developed DIC during hospitalization (p=0.001). The use of Daunorubicin had 6.252 times significantly (p<0.05) increased risk to developed DIC with 95.0% CI (0.107 to 36.048%). Patients with DIC had more bleeding 10(83.3%) than the non-DIC group 20(46.6%). The mortality rate was higher, 3(25.0%) in the DIC group and 6(14.0%) in the non-DIC group. The frequency of DIC was 21.8% during the induction period, use of daunorubicin was identified as the risk factor for the development of DIC. Mortality was higher in patients with DIC.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1133-1143"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Online Teaching and Academic Performance among Medical Students during Covid-19 Pandemic.","authors":"M N Akhi, F F Ahmed, M K Amin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nearly every sector in the world was impacted by Covid-19, including the higher education and medical education systems. Distance learning is a recent development in Bangladeshi medical education. It is still unknown how online learning affects academic performance. This study aimed at assessing the association between online teaching and academic performance of medical students during Covid-19 pandemic. This cross-sectional descriptive type of observational study was carried out at Dhaka National Medical College and Shaheed Suhrawardy Medical College in the city of Dhaka and involved 202 4th-year medical students of both sexes. Purposive sampling was used to take samples. With the aid of a semi-structured questionnaire and a checklist, data were gathered via in-person interviews and record reviews, respectively. The study's results were displayed in tables and graphs as percentages, frequencies, and frequency distributions for categorical variables, along with means and standard deviations for continuous variables. Fisher's Exact test and the Chi square test were both used to evaluate associations between categorical variables. Among 202 students, with mean ±SD age of 23.04±0.969 years, 54.00% were female. Majority (78.70%) of students resided in urban areas that had monthly family income between TK.15000-TK.50000. For online classes, 76.20% students used smart phones for Zoom platform (85.60%) with 4G service (74.3%). Students had difficulty in interacting with teachers (55.4%), had illness (42.60%), among which vast majority (59.30%) complained of headaches. A major portion of the students (56.9%) felt that studies were hampered by the pandemic and thus suffered from mental pressure (63.9%) resulting in 75.0-79.0% class attendance (54.50%). Item score was 6.0-6.9 out of 10 in 60.9% students and 94.10% passed the second professional examination. Mass online learning is a fresh idea made possible by the pandemic. Given that medical education is heavily practice-based, it is important to investigate how online teaching affects students' academic performance.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1199-1206"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Animal Sacrifice during Eid-ul-Adha: How Far are we from a Standard Practice?","authors":"M J Hasan, M Ahmed, M Sanaullah, S Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>No Abstract.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"952-953"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Presence and Position of Lingual Foramina in Dry Adult Human Mandible.","authors":"M Ahmed, M Akter, S M A Haque, M S Latif, S Islam, A A Jewel, M A A Mamun, M S Nahyan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lingual foramina are present on the inner surface of the anterior portion of body of mandible. These foramina provide passages of neurovascular structures to the mandible. The aim of the study was to identify these foramina if present, as well as their different positions in the anterior mandibular regions. This cross-sectional descriptive study was done on 150 fully ossified dry human mandibles in the department of Anatomy, Mymensingh Medical College, Bangladesh from July 2019 to June 2020. A non-random purposive sampling technique was adopted. Study was carried out by observations only. Lingual foramina were classified into midline position behind the symphysis menti and lateral position to symphysis. Again, in midline, they were grouped into three groups in relation with the position of genial tubercle (mental spine) as supraspinous, interspinous and infraspinous positions. Lingual foramina were present in all samples. In 96.0% samples, foramina were located in midline and rest 4.0% having lateral foramina. In midline position, they were grouped in relation with the mental spine. Among 144 samples, 79.86% foramens were found above the spine (supraspinous), 4.86% foramens found in between the spine (interspinous) and 15.27% foramens found below the spine (infraspinous). Study of these mandibular foramina helps to lower the per and post operative complications such as hemorrhage and hematoma formation in operations like implant placement, autogenous bone graft etc.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1231-1233"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial Effect of Trimetazidine on Streptozotocin Induced Diabetic Nephropathy in Rats by Enhancing Glutathione Status.","authors":"M N Sathi, S Rahman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Trimetazidine increase glutathione peroxidase and limits membrane damage caused by reactive oxygen species (ROS). It also has cytoprotective effect and limits the production of trimethylamine N-Oxide (TMAO) and provides the renoprotective effect. This study was designed to evaluate the renoprotective effect of trimetazidine (TMZ) in an experimental model of streptozotocin (STZ induced diabetic nephropathy in rats. For this experimental study sixty-six rats (66) were divided into eight groups. Group I (C1) and group II (C2) were normal healthy rat groups and sacrificed on 22nd day. Three groups of rats were induced diabetic nephropathy by streptozotocin (STZ) single intraperitonial administration at a dose of 50mg/kg body weight. Biochemical indices like serum blood sugar and the status of oxidative stress was assessed by renal cortical glutathione (GSH) levels. In streptozotocin treated groups, renal glutathione was significantly (p<0.01) lower when compared to control. In TMZ treated group, whereas renal glutathione was significantly (p<0.01) higher when compared with STZ induced nephropathy groups of rats. It may be assumed from this study that trimetazidine has nephroprotective effects because of its special antioxidant effects, which can delay the onset, severity and progression of nephropathy induced by streptozotocin in rats. Therefore, trimetazidine may be extensively studied in human with diabetic nephropathy for confirmation of its nephro-protective effects.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1157-1161"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Transverse Fracture of Shaft of Femur by Intramedullary Interlocking Nail with Dynamic Locking.","authors":"K M R Hasan, Z Haq, A K M Haque, M M Hasan, B K Das, M R Hasan, M S Rahaman, M J Hasan, S Saha, M H Samarat","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fractures of the shaft of the femur are among the most common fractures encountered in orthopaedic practice. The goal in treating a femoral shaft fracture is to promote union, mobilize the patient and restore the function of the limb. The aim of the study was to evaluate the effectiveness of primary dynamization with intramedullary interlocking nail for the treatment of femoral shaft fracture (AO type 32-A3). This prospective study was conducted in National Institute of Traumatology and Orthopaedic Rehabilitation (NITOR), Dhaka, Bangladesh from July 2017 to June 2019. Fifty (50) patients with closed transverse fracture shaft femur (AO type 32-A3) were selected purposively as study participants. Patients with open fracture, pathological fracture, bilateral fracture and fracture at the lower third or neck of the femur were excluded from the study. All patients were treated with primary dynamization with intramedullary interlocking nail and followed up for one year. Final outcome was assessed using Thoresen criteria. The mean ±SD age of the patients was 32.5±11.8 years where most of the patients (92.0%, n=46) were male. The mean ±SD duration of injury of the patients was 13.9±4.7 days and 6 patients (12.0%) had associated injuries. Forty four (44) patients completed the one year follow up. According to the Thoresen criteria, majority of the patients (59.1%, n=26) had excellent outcome and near about one fifth of the patients (22.7%, n=10) had good outcome. Others had moderate (15.9%, n=7) and poor outcome (2.3%, n=1). Excellent outcome was significantly more among patients without associated injury (p=0.036). Primary dynamization with intramedullary interlocking nail is effective for the management of transverse fracture shaft of femur (AO type 32-A3).</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 4","pages":"1103-1109"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}