Mymensingh medical journal : MMJ最新文献

{"title":"Variation of Antero-Posterior Diameter of Corpus Callosum in Different Age and Sex Groups of Bangladeshi People.","authors":"L Jabeen, S A Sumi, N J Khan, N S Nitu, S K Bose","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The corpus callosum (CC), the largest commissure of the brain, connects the two cerebral hemispheres and lies at the bottom of the longitudinal fissure. The antero-posterior diameter of the CC was larger in males than in females, but this difference was not significant. Again, the length of CC increased with age and there was also a positive significant correlation between the antero-posterior diameters of the CC with the antero-posterior diameter of the brain. This cross sectional descriptive study was performed into four categories: Group A (20-29 years), Group B (30-39 years), Group C (40-49 years) and Group D (50 years and above). The specimens were collected from morgue in the department of Forensic Medicine, Mymensingh Medical College, Bangladesh by purposive sampling technique Octy 2016 to Octy 2017. The antero-posterior diameter of CC was measured by using thread. The mean maximum antero-posterior diameter of corpus callosum was 8.25 cm in group D and minimum was 7.92 cm in Group A. When the diameter was compared between sexes in different age groups, it was significant in Group D and moderately significant in Group C. There was a positive correlation between antero-posterior diameter of corpus callosum and age of individual and it was statistically not significant. For statistical analysis, differences between age and sex groups were analyzed by using students unpaired 't' test. The present study will help to increase the information pool on the antero-posterior diameter of CC of Bangladeshi people and thus will minimize the dependency on foreign standards and also have diagnostic importance for the neurosurgeons and radiologists for clinical investigation and surgery.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1070-1074"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Calf Circumference with Body Weight of 5-10 Years Aged Bangladeshi Children.","authors":"M Ismatsara, E Z Epsi, S Tanzeem, S M A Haque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The cross-sectional, analytic and descriptive type study was conducted among 5-10 years aged Bangladeshi children at different areas of Mymensingh district (Muktagacha, Fulbaria, Trishal, Haluaghat and Fulpur thana) on 109 Bangladeshi children (39 female and 70 male). The study was conducted in the Department of Anatomy, Mymensingh Medical College, Bangladesh. Nonrandom purposive sampling technique was taken for sample collection. Any kind of leg and foot deformity resulting either from congenital anomaly or physical injury was excluded to construct standard data. The present anthropometric study was designed to construct data of 5-10 years aged Bangladeshi children regarding calf circumference, to measure correlation calf circumference (right) with body weight and comparison of calf circumference (right) between male and female children. The study has been made out to grow interest among the researchers for future study and also to compare the data with the data of the people of other races of different country. Body weight was recorded by weighing machine and calf circumference was measured by measuring tape. Calf circumference (right) showed non-significant positive correlation with weight in 5 years old male, 6 and 7 years old male and female, 8 years old male, 9 years old female and 10 years old male and female children. In case of 5 years old female and 9 years old male children, it showed significant positive correlation with weight but in case of 8 years old female, it showed non-significant negative correlation with weight. Comparison of calf circumference (right) between male and female children was done by Unpaired Students' 't' test which was statistically non-significant.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1058-1063"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Adrenal Hyperplasia: Experience from Dhaka Shishu (Children) Hospital, Bangladesh.","authors":"R Biswas, A B Kamrul-Hasan, S N Rahman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There is a scarcity of data on congenital adrenal hyperplasia (CAH) in Bangladesh. This study aimed to collect baseline information and identify relevant issues specific to the disease. We analyzed the retrospective analysis of medical records of pediatric patients attending Dhaka Shishu (Children) Hospital, Dhaka, for serum 17-Hydroxyprogesterone (17-OHP) measurement and documented to have CAH from December 2008 to December 2020. The diagnosis was supported by biochemical findings and confirmed by serum 17-OHP assay and karyotyping. The relevant clinical data were descriptively analyzed. A total of sixty (60) patients with the diagnosis of CAH were enrolled. Among them, 40(66.7%), 15(25.0%) and 5(8.3%) patients had salt-wasting (SW), simple virilizing (SV) and non-classical (NC) CAH, respectively. Karyotypically, 45(75.0%) were girls and 15(25.0%) were boys. At presentation, 30(50.0%) were initially assigned as female and 24(40.0%) were male and in 6(10.0%) cases, the sex was not assigned. All six cases of unassigned sex were proven to be female by karyotype, while ninecases assigned as males were proven to be females; overall, 15(25.0%) patients were incorrectly assigned sex at the initial presentation. Patients with SW form of disease presented at an earlier age (median age 1.0 months) than those with SV form (median age 12.0 months). Boys were diagnosed later than girls. CAH should be diagnosed earlier, irrespective of the sex of the child, to prevent death from the salt-losing crisis and proper gender assignment. In a resource-poor country like Bangladesh, we should emphasize building awareness among the general population and caregivers for early clinical identification of the cases and proper referral.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1075-1080"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Alternative Diagnostic Test rather than 24 hours Urinary Protein to Detect Massive Proteinuria in Nephrotic Syndrome in Mymensingh Medical College Hospital, Bangladesh.","authors":"F Akhter, M A Hoque, M N Islam, M Akhtaruzzaman, B Chowdhury, M J Hussain, S E Amin, S S Sultana, K Begum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This cross-sectional study was conducted in Department of Paediatrics, Mymensingh Medical College Hospital (MMCH), Bangladesh from February 2016 to December 2016 to detect massive proteinuria by spot urinary protein creatinine ratio as an alternative diagnostic test to 24 hrs urinary total protein in nephrotic syndrome. Fifty one (51) children aged 2 to 12 years admitted with 1st episode of nephrotic syndrome in the pediatric department of MMCH were included in this by purposive sampling technique. All the patients were asked to give a 24 hours urine sample. After this collection the next spot urine samples were collected for protein and creatinine estimation. Among 51 patients 33 were male and 18 were female. The mean age was 5.5+2.3 years. The entire patient had normal renal function. The mean 24 hours urinary protein level was 3.8±1.7 gm/m²/24 hours, the mean spot urinary protein-creatinine ratio was 5.4±2.5. Mean serum albumin was 1.8±0.6 gm/dl and the mean serum cholesterol was 357.6±74.7 mg/dl. The spot urinary protein creatinine ratio was increased with the increase in the amount of 24 hours urinary total protein and a strong positive Pearson correlation (r=0.805) was found. In all the cases of nephrotic syndrome spot urinary protein creatinine ratio were found more than 2. Based on this study, it can be concluded that the determination of the spot urinary protein-creatinine ratio can replace the 24 hours urine collection in the quantitation of proteinuria in nephrotic syndrome.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1026-1032"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic and Clinical Characteristics of Covid-19 Positive Cases: An Exploratory Retrospective Study in a Covid-19 Referral Hospital.","authors":"M A Islam, A S M Kabir, S M Sadlee, U S Mou, M H Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In late 2019, a novel coronavirus emerged in Wuhan, China, causing an atypical pneumonia- like illness. Scientists subsequently isolated the virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), in January 2020. This highly contagious virus rapidly spread worldwide, triggering a global public health emergency. The ongoing Covid-19 pandemic necessitates continuous evaluation of the characteristics of infected individuals. This study aimed to investigate the demographic and clinical features of patients diagnosed with Covid-19 at a tertiary care hospital in Bangladesh. This retrospective cross-sectional study was conducted between November 2023 and February 2024 at the Department of Respiratory Medicine, Uttara Adhunik Medical College Hospital (UAMCH), Dhaka, Bangladesh. The study involved collaboration with the departments of Virology and the hospital's Covid Unit. Data were collected from the medical records of 200 confirmed Covid-19-positive cases admitted upon arrival at the hospital. Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) version 23.0. Of the 200 participants, the most frequent age group was 46-60 years old, representing 42% (84 patients). Males comprised the majority (73.0%, 145 patients), and most participants resided in urban areas of Bangladesh (86.5%, 173 patients). The socioeconomic analysis revealed that the upper-class category had the highest frequency (85.0%, 170 patients). Diabetes Mellitus (DM) emerged as the most prevalent co-morbidity (58.5%, 117 patients). Regarding clinical presentation, fever was the most frequent symptom (76.0%, 152 patients), followed by cough (47.5%, 95 patients), shortness of breath (SOB) (27.5%, 55 patients), and pneumonia (15.0%, 30 patients). Less frequent symptoms included acute respiratory distress syndrome (ARDS), lower respiratory tract infection (LRTI), and chest pain. The mean systolic and diastolic blood pressure readings were 126.61±14.58 mmHg and 77.24±12.44 mmHg respectively. The mean oxygen saturation (SaO2) was 93.39±5.53%. This study investigated that the most frequent age group was (46-60) years. The male dominant in Covid-19-positive cases. Diabetes Mellitus (DM) was observed as the most frequent co-morbidity. The common symptoms of Covid-19-positive cases were fever, cough, SOB, pneumonia acute respiratory distress syndrome, lower respiratory tract infection, chest pain, high blood pressure and low oxygen saturation.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1250-1257"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Relapsed or Refractory Diffuse Large B-cell Lymphoma with Second-line Chemotherapy Ifosfamide-Carboplatin-Etoposide with or without Rituximab.","authors":"S Haque, Z Z Chowdhury, T Bahar, S T Reshma, A K M Islam, M Ali, M M Rahman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Treatment of relapsed or refractory diffuse large B-cell lymphoma is difficult. The de novo diffuse large B-cell lymphoma has better prognosis than the transformed diffuse large B-cell lymphoma. The response of CHOP or a similar regimen has an important role in determining response to salvage therapy, in relapse or refractory diffuse large B-cell lymphoma patients. Patients who are non-responder to initial treatment have a very poor chance of responding to therapy for relapse. This was a small scale observational study and was conducted from January 2017 to December 2020 in National Institute of Cancer Research and Hospital, Bangladesh. A total of 34 patients with relapsed or refractory diffuse large B-cell lymphoma were identified at hematology department in National Institute of Cancer Research and Hospital, 28 of them were treated with ICE chemotherapy and 6 with R-ICE chemotherapy as second line regimen. Overall response rate to 2nd line chemotherapy was 64.8%, with 32.4% (11 patients) complete remission and 32.4% (11 patients) partial remission. Median overall survival to second line regimen was 10 months, corresponding to a 4 year overall survival of 32.4% and a 4 year progression free survival was 17.6%. Patient with stable disease/progressive disease median overall survival was 7 months compared with 15 months for complete remission and 9 months for partial remission (p<0.001). Median overall survival was significantly better in patients with international prognostic index 0-2 compared in those with international prognostic index >2 (p=0.010). However improvement of salvage efficacy is an urgent need with new drugs. Further studies are necessary to determine whether this regimen will improve outcomes of relapsed or refractory diffuse large B-cell lymphoma patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1176-1183"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Primary and Recurrent Breast Cancer after Giving Adjuvant Therapy in Correlation with the Receptor Status.","authors":"S A Azad, M S Rahman, A K M Bhuiyan, M J Islam, S U Ahmed, A F M Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Breast cancer is the most common type of cancer among women. The molecular subtypes of breast cancer, depending on the Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal Growth Factor Receptor (HER-2) status, usually play a vital role for the adjuvant treatment. Interestingly, there is a good possibility of change of receptor status in the recurrence of same primary tumor. The study is designed April 2018 to March 2019 to see the concordance in triple-receptor expression (ER, PR, and HER-2) between the primary and the locally recurrent breast cancer patient and the results can be able to influence the management and prognosis of the breast cancer patients. This observational study was carried out in the department of surgical oncology, NICRH where total 48 patients were studied who were subjected to core biopsy of recurrent lesion for ER, PR and HER-2 status. A structured case record form was used to interview and collect data. Data analysis was done using SPSS version 26.0 to see concordance and discordance in triple-receptor expression between the primary and the locally recurrent breast cancer patient. Among 48 cases, 12(25.0%), 10(20.83%) and 2(4.16%) patients showed Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal Growth Factor Receptor (Her-2) discordance that are statistically significant in every receptor status. Majority discordance of ER, PR and Her-2 were associated with invasive duct cell carcinoma (IDC); ER & Her-2 discordance was equally associated with histological grade 2 and 3 whereas PR discordance had significant association with grade 3. Staging of disease showed that all ER, PR and Her-2 discordance were associated with stage (p<0.05). Besides, majority discordance was mostly associated with lumpectomy except Her-2 discordance. Besides, among the adjuvant treatment regimen chemotherapy along with radiotherapy was mostly associated with discordance of all receptors (p<0.05). Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal Growth Factor Receptor (HER-2) status of primary breast cancer showed 25.0%, 20.83% and 4.16% discordant in recurrent episodes in this study. Invasive duct cell carcinoma, histological grade 2 and 3, stage II, stage III, MRM and CT along with RT are major attributable factors in this study.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1204-1210"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Short-term Breathing Exercises on Different Cardio-Respiratory Parameters.","authors":"G A Birajdar, N M Bhosale, K H Buge, S M Hulke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cardiorespiratory health is one of the critical parameters for improving endurance. Breathing exercises in the form of various Pranayama have a significant effect on cardiorespiratory health. To assess the effect of breathing exercises in the form of various pranayamas on cardiorespiratory parameters in people living with sedentary lifestyles. This longitudinal study was done on 30 subjects aged 25 to 35 years. Participants performed Bhastrika, Kapalbhati, Anulomvilom and Bhamri Pranayama with prayers and warm-up for 10 to 40 minutes, progressively increasing over one year. The average daily duration in the initial 3 months was 15 minutes; in the next three months, it was 23 minutes. The average daily duration in the last 6 months was 34 minutes. Cardiorespiratory functions were assessed using Spiro Excel machine spirometer and Mercury sphygmomanometer (Diamond) at the time of enrolment and the end of 1 year of the study. A paired t-test, using statistical software, was used to analyze parameters. In males and females, significant change is observed in pulse rate, systolic blood pressure and diastolic blood pressure. In pulmonary function test parameters, non-significant change was observed in forced expiratory volume in 1 sec (FEV₁) and forced vital capacity (FVC); other parameters, i.e., FEV₁ as percentage of FVC in % [FEV₁ (%)], peak expiratory flow rate in L/s (PEFR) and Minute Ventilation Volume (MVV) L/min showed significant change in males and females. Breathing exercises in the form of various Pranayama positively affect cardiorespiratory health, and further studies are recommended in the diseased population.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1273-1279"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Totally Tubeless and Tubeless Percutaneous Nephrolithotomy with Standard Techniques.","authors":"F H Siddique, M I Ali, M A Amin, P P Chowdhury, N Alam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Traditionally, percutaneous nephrolithotomy (PCNL) includes placing a nephrostomy tube and a Double J (DJ) stent to drain the kidney and operative tract following the procedure. However, more recent techniques, such as tubeless or totally tubeless PCNL, eliminate these drainage methods. The objective was to assess the feasibility, safety and effectiveness of performing tubeless or totally tubeless PCNL in comparison to standard PCNL a retrospective analysis was performed on 156 patients who underwent PCNL treatment From September 2022 to September 2023. Of these, 78 patients received traditional nephrostomy PCNL, while 46 patients underwent the tubeless procedure and the remaining 32 received the totally tubeless procedure. The three groups showed no significant differences in preoperative patient characteristics. The operation time, analgesic requirements and hospital stay were lower in the tubeless and totally tubeless PCNL group than in the standard PCNL group (p<0.05). No significant differences were found in the mean stone size, stone-free status or the occurrence of major complications. The overall complications (Grade-1, 2 and 3) rate was 14.2% in the standard PCNL group, 8.7% in the tubeless PCNL and 9.4% in the totally tubeless PCNL group. The tubeless and totally tubeless PCNL techniques have proven to be safe and effective, even for patients with incomplete staghorn stones and a moderate pelvic stone burden. These approaches are associated with reduced pain, lower analgesic needs, shorter operative times, and decreased hospital stays, making them more cost- effective and less likely to result in complications, while also improving patient satisfaction. Further research is essential to validate the safety of these techniques, encouraging urologists to adopt them in clinical practice.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"980-988"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Antibacterial Activities of Aqueous Extract of Black Pepper (Piper nigrum L) Seeds against the Gram Positive Staphylococcus aureus and Gram-Negative Escherichia coli.","authors":"M A Hossain, S M Ahmed, K E Zannat, A Afrin, T A Banu, T S Dema, E F Nishat, J Ferdous, A Nawar, U J Ferdaus, S M Tanzim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Antibiotic resistance (AMR) represents a serious threat to public health and poses challenges in disease prevention and treatment despite various efforts to combat it. Evaluation of the in vitro antibacterial activity of aqueous extracts of black pepper seeds (Piper nigrum L.) against two infectious pathogens: Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The Department of Pharmacology and Therapeutics and the Department of Microbiology of Mymensingh Medical College conducted the study from Octy 2022 to June 2023. The antibacterial activity of Aqueous black pepper seed extract (ABPE) was evaluated at different doses using disk diffusion and broth dilution methods. The extract was prepared using 10.0% dimethyl sulfoxide (DMSO) and water as solvent. The commonly used antibiotic ciprofloxacin was used in the broth dilution method and the results were compared with those for aqueous extracts. To confirm a more precise range of antimicrobial susceptibility of the extracts, ABPE was used at seven different concentrations (100, 80, 60, 40, 20, 10 and 5 mg/mL). Selected concentrations were then used as needed. ABPE showed an inhibitory effect on the above bacteria at doses of 90 mg/ml and higher. The Minimum inhibitory concentration (MIC) values for Escherichia coli and Staphylococcus aureus were 85 and 90 mg/ml ABPE, respectively. The MIC of ciprofloxacin against Staphylococcus aureus and Escherichia coli was currently 1μg/ml. The MIC of ciprofloxacin was lowest for the organisms tested compared to the MIC of ABPE. This work clearly demonstrates the antibacterial sensitivity of Staphylococcus aureus and Escherichia coli to an aqueous extract of black pepper seeds.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"33 4","pages":"1002-1008"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}