Mymensingh medical journal : MMJ最新文献

{"title":"Assessment of the Change of Body Mass Index, Serum Uric Acid in Post Menopausal Women.","authors":"S Yesmin, A Nessa, N Khatun, M Paul, S Firoz, A Begum, S S Suchi, I A Tanvir, S T Tithi, N Sultana, S Sadia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Menopause, due to decrease level of estrogen in women between the ages of 45-55 years, is a natural process that is characterized by the complete stoppage of menstrual cycle is called menopause. Because of imbalance of hormone mainly estrogen the efficiency of life is disturbed as a result various postmenopausal syndromes such as irritability, night sweats, vaginal dryness, hot flushes, depression, sleep disturbance and headache can occur in this period. This study was done to evaluate the changes of Body mass index (BMI) and serum uric acid in postmenopausal women in comparison to reproductive women. This analytical type of cross sectional study was carried out in the Department of Physiology, Mymensingh Medical College, Bangladesh from January 2023 to December 2023. A total number of 200 healthy women were enrolled in this study. Among them, one hundred (100) female subjects were taken as control group (Group I) age ranges from 25-45 years and one hundred (100) female subjects were taken as study group (Group II) age ranges from 45-65 years. BMI was calculated by anthropometric measurement such as height and weight was taken in meter and kilogram respectively and serum uric acid is expressed in mg/dl. Output were expressed as mean±SD and by using unpaired students' 't' test, statistical significance of difference among the group was calculated. The mean±SD of BMI of Group I and Group II were 21.91±1.57 kg/m² and 26.92±2.06 kg/m² respectively. In the study group the mean±SD of BMI is notably increased in study group in comparison with control group. The mean±SD of serum uric acid of Group I and Group II were 4.18±1.33 mg/dl and 7.36±0.46 mg/dl respectively. In the study group the mean±SD of serum uric acid was notably increased in study group in comparison with control group. Postmenopausal women with higher BMI and serum uric acid caused by lower level of female sex hormone specially estrogen hormone increased the change of cardiovascular disease, stroke, chronic renal failure, type-2 diabetes mellitus, insulin resistance and metabolic syndrome. So, the assessment of this parameter is important for early detection and prevention of complication related to higher BMI and serum uric acid for leading a healthy life.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"351-354"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Artificial Intelligence in Scientific Writing.","authors":"M K Khan, J Ferdous, G Mourshed, S B Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Artificial Intelligence (AI) is revolutionizing various fields, including scientific writing, which traditionally relies on human intellectual effort. This review article explores the evolving role of AI in scientific writing, highlighting its applications, challenges and ethical implications. The adoption of AI in scientific writing offers several key advantages that make it attractive to researchers. AI-powered tools are employed to scan large volumes of academic literature quickly and efficiently. AI writing assistants have become increasingly sophisticated in generating human-like text. AI-driven language models can help authors who are not native English speakers to produce high-quality, well-written manuscripts. Another significant benefit is the ability to handle large amounts of data efficiently. Moreover, AI tools reduce the risk of plagiarism by detecting unintentional similarities between newly drafted manuscripts and previously published work. AI systems are also being developed to assist with the peer-review process. Automated tools use AI to analyze manuscripts, checking for completeness, adherence to journal guidelines and even suggesting potential reviewers. Furthermore, AI aids in citation management by helping researchers organize and insert references correctly. Despite the benefits of AI in scientific writing, several ethical considerations and challenges accompany its adoption. A significant concern relates to the potential over-reliance on AI for generating text and performing critical analyses. Additionally, the question of authorship becomes increasingly complex with the involvement of AI in writing. Another significant issue concerns the potential for bias in AI-generated content. AI models are trained on vast amounts of data, which often reflect existing biases in published literature. This is particularly concerning in fields such as healthcare, where biased research could have serious consequences for patient care and treatment outcomes. Finally, the use of AI raises concerns about data privacy and security. As AI continues to evolve, it is essential for the scientific community to establish guidelines that ensure the responsible use of these tools, maximizing their benefits while mitigating potential risks.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"592-597"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Young Patient with Amyotrophic Lateral Sclerosis Following Suicidal Organophosphorus Compounds Poisoning: A Case Report.","authors":"M Saiduzzaman, S Roy, M Bhattacharjee","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease involving both upper and lower motor neurons. Its underlying etiology is not well established. But certain risk factors including genetic predilection and exposure to certain environmental toxins like Organophosphorus Compounds (OPC) have been postulated. Here we describe a young male patient presented with progressive weakness of all four limbs immediately following survival from OPC ingestion as a suicidal attempt. He also had slurred, indistinct speech without swallowing difficulty and sensory findings. Neurological examination findings are having mixed upper and lower motor neuron signs. EMG (Electromyography) shows features of denervation and reinnervation suggestive of ALS. ALS following single exposure to OPC is a relatively rare finding. Supportive treatments including physiotherapy and psychotherapy were given. This case may strengthen the etiological link between OPC and ALS.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"272-275"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Hearing Recovery Two Years Following Onset of Bilateral Sudden Sensorineural Hearing Loss: Miracle May Happen any Time.","authors":"H A R Talukder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sudden sensorineural hearing loss is a medical emergency. Incidence is very low. Unilateral SSNHL is common and mostly idiopathic. Spontaneous recovery rate is 30-65% within 2 weeks. Bilateral SSNHL is a rare subset, less than 5% of reported SSNHL and higher association with systemic disease. Prognosis is very poor following treatment. Recovery of hearing after 3 months following SSNHL is a very rare entity. Spontaneous hearing gain after a long time is a miracle that happened in the reported case. A 12-year-old female child suddenly recovered serviceable hearing few days prior to the date of cochlear implant surgery following SSNHL. She developed a very rare bilateral sudden sensorineural hearing loss two years back. Bilateral sudden sensorineural hearing loss is a rare subset though unilateral SSHL is little common. Recovery of hearing occurs mostly within two weeks, very rare beyond sixty days. Our case reported sudden hearing gain about two years after insidious SSNHL. Explanations not clear provably reestablishment of vascularity to cochlear or spontaneous elimination of underlying cause. No available data found, further study is needed.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"285-289"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of High-Sensitivity C-reactive protein in Patient with Early Parkinson's disease.","authors":"M M Emran, S S Malik, M Wahiduzzaman, G K Paul, N Fatema","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parkinson's disease (PD) is a common neurodegenerative disorder. The pathogenesis of PD is unknown till now. The high-sensitivity C-reactive protein (CRP) is a non-specific biochemical marker of inflammation. It is used for the screening of organ diseases and the monitoring of responses to treatment in cases of inflammation and infection. This study aimed to evaluate the relationship of high-sensitivity C-reactive protein in early Parkinson disease. A total of seventy-six early Parkinson's disease patients were enrolled in this Cross-sectional observational study which was carried out in the Department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from September 2014 to March 2016. We assessed high sensitivity CRP of early Parkinson's disease patients as an inflammatory marker. This study was performed with 76 early Parkinson disease patients. Among them, male and female were 69.7% and 30.3% respectively. The mean ±SD age of patients was 53.25±11.53 years with an age range of 24 to 77 years. The mean ±SD value of high-sensitivity C-reactive protein was estimated 2.76±3.57 mg/L with the range of 0.21 to 20.90mg/L. We also calculate the 95% CI in the range of 1.96 to 3.56mg/L. Also, a positive and highly significant correlation were seen in between duration of tremor and High sensitivity CRP (r=0.430, p<0.001) and between duration of bradykinesia and High sensitivity CRP (r=0.426, p<0.001) which indicate increase duration causes increase level of high-sensitivity C-reactive protein value. In conclusion, above findings suggests that neuro-inflammation plays a significant role in the pathogenesis of early Parkinson's disease progression.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"159-165"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV Vaccination in a Case of JORRP, a Variety of RRP in Bangladesh Medical College Hospital: A Case Report.","authors":"S Jebunnaher, T Mohammad, M A Jaigirdar, M A Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recurrent respiratory papillomatosis (RRP) is a rare disease which is caused by human papilloma virus (HPV). It is a warty growth in the upper airway may cause significant airway obstruction or voice change. Though it is rare but one with severe morbidity and occasional mortality. It is caused mostly by HPV 6 and 11. Juvenile-onset recurrent respiratory papillomatosis (JoRRP) which is Juvenile form of RRP affects children, most common between the ages of 1 to 4 years.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"290-294"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Drug Use Pattern in Dermatology Out-Patient Department: A Cross-Sectional Study in a Tertiary Care Teaching Hospital, Dhaka, Bangladesh.","authors":"H Begum, M A Baker, A N Asma, Z Rahman, A N Dina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Now-a-days, all over the world, skin disease are the fourth most common cause of disability. A significant amount of patient attending the dermatology outdoor of any major hospital in a daily basis. Irrational drug prescribing is a common contemplation in clinical practice. The present research work was commenced to study the drug use pattern and rationality of prescriptions of the patients be at Dermatology Out-Patient Department (OPD) of a tertiary care hospital. It was an observational, single center study, conducted among 600 patients attending the Dermatology OPD of Enam Medical College and Hospital (EMCH), Bangladesh for a period of six months by interviewing the patients and detailed were filled in predesigned form. Overall 600 drug instructions were collected and surveyed for demographic as well as dermatological profile. Antihistamine (16.95%), antibacterial (14.69%), antifungal (10.73%) and corticosteroids (8.47%) were the most recurrent class of drugs ordered. Combination form (oral + topical) was mostly instructed (61.80%). Polypharmacy was seen (3.54 drugs per prescription) in our study, very few drugs (1.97%) name were written by generic name. antihistamine were most frequently advised drug groups. Least amount of drugs was prescribed from Essential Drug List (EDL) of Bangladesh. Interim auditing is necessary to promote standard prescription.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"220-226"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Free Tri-iodothyronine Level and In-Hospital Outcome in Patients with Acute ST-Elevation Myocardial Infarction Treated with Streptokinase Therapy.","authors":"S M N Huda, A K Choudhury, P K Karmakar, B Mondal, S Ahmed, S C Datta, A Rahman, D D Debnath, M S Aktar, M Tabassum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Low free Tri-iodothyronine (FT₃) levels are generally associated with poor prognosis in patients with various critical illnesses. Acute ST-segment Elevation Myocardial Infarction (STEMI) represents the most lethal form of Acute Coronary Syndrome (ACS) with substantial short- and long-term mortality. This study was done to assess the association between FT₃ levels and in-hospital outcome of the STEMI patients treated with streptokinase therapy. This was an observational study of 140 patients of STEMI treated with streptokinase therapy in the department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh from October 2018 to September 2019. The patients were divided into the low FT₃ (FT₃ <3.5 pmol/L; n=70) and the normal FT₃ (FT₃ ≥3.5 pmol/L; n=70) groups according to FT₃ levels measured within 24 hours after admission. During the index hospitalization period, 13 patients died (9.0%) and the overall mortality rates were 18.6% in the low FT₃ group and 5.7% in the normal FT₃ group (p=0.01). The rates of Major cardiac events (MACE) were 45.7% in the low FT₃ group and 18.6% in the normal FT3 group (p=0.001). Multivariate logistic regression analysis showed FT₃ level is an important predictor for in-hospital major cardiac events in patients with ST-elevation Myocardial Infarction (p=0.01). Low FT₃ levels were strongly associated with poor in-hospital outcome in patients with STEMI. The FT₃ level screening may be a simple and valuable way in identifying high-risk STEMI patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"153-158"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International Staging System Status and Trend of Relapse in Multiple Myeloma Cases in a Tertiary Level Health Care.","authors":"M M Alam, M A Khan, M Akter, M Wasim, M N Alam, R Nahar, T Islam, M S Basher, M N Islam, M N Karim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Multiple myeloma (MM) is a haematological neoplasm of mature B-cell lineage origin. It is characterized by abnormal clonal proliferation of plasma cells and presence of monoclonal protein in serum and / or urine. This study was conducted to observe the International Staging System (ISS) status and trends of relapse. This descriptive cross-sectional study was performed in the department of Haematology, Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2019 to July 2020 among 81 purposively selected Multiple myeloma patients. Principal investigator collected data using Case Record Form (CRF) after obtaining informed consent. Relevant ethical issues and data quality assurance were taken into consideration. Data were analyzed with Statistical Package for Social Sciences (SPSS), Version 25.0. Chi square test, Fisher's exact test and Chi square test with Yate's correction were carried out as appropriate with five percent level of significance for assessing statistical association. Mean age of patients with Multiple myeloma was 58.9±12.0 years. Male female ratio was nearly 2:1. ISS stage III was in 59.4 percent cases, lytic lesions were present in 75.0% and mean Bone Marrow Plasma Cell (BMPC) percentage was 62.1±24.9 percent. Immuno-Fixation Electrophoresis (IFE) revealed IgG Kappa (47.3%), IgG Lambda (25.5%) IgA Lambda (10.9%), IgA Kappa (7.2%) and Free Light Chain (9.1%). Kappa lambda ratio was 60.7:39.3. Free Light Chain (FLC) ratio ≥100 was in 29.0 percent cases. Four-fifths 65(80.2%) cases were de novo, while nearly one-fifth 16(19.8%) were the relapsed cases. Mean duration to become relapsed or refractory was 37.6±19.4 months. Significant association was observed among advanced ISS staging with refractory or relapse. Erythrocyte sedimentation rate in 1st hour (ESR), FLC ratio, FISH cytogenetics, Immunofixation electrophoresis (IFE) and treatment protocol was not found to have statistical association with relapse or refractoriness (p>0.05). A significant number of cases are de novo; while nearly one in five are relapsed one. Mean duration for refractoriness is 37.6±19.4 months. Patients are treated with established chemotherapeutic protocols. About one-fifth of patients developed refractoriness with progression of time.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"174-180"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Helicobacter Pylori Infection with Functional Dyspepsia.","authors":"M R Karim, M S Alam, A Islam, M S Malek, M S Ahsan, E Mia, S Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Helicobacter pylori (H pylori) infection is known to be associated with dyspepsia for more than three decades. This study was conducted to investigate the frequency of H pylori infection in functional dyspepsia. Helicobacter pylori infection was detected by stool antigen tests were analyzed in 102 patients with functional dyspepsia. The functional dyspepsia was diagnosed according to Rome IV criteria as well as normal upper GI (Gastro-intestinal) endoscopy and abdominal ultrasonography within six months. In this study, H pylori infection rate diagnosed by the stool antigen test was detected to be 26.5% among the people with functional dyspepsia. Sex-based proportion H pylori infection was 21.2% for men and 29.0% for women with functional dyspepsia. The highest prevalent group with Helicobacter pylori infection was 30-39 years. In this study, 25.75% of rural participants and 27.78% of urban participants with functional dyspepsia were positive for H pylori. The stool antigen positive group and the stool antigen negative group were not significantly different in respect to age (p=0.29), sex (p=0.41) and residence (p=0.82). This study showed an increased stool antigen positivity rate for H pylori infection among the patients with functional dyspepsia. Further studies are required to determine the exact prevalence of H pylori among this group of patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"74-78"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}