Mymensingh medical journal : MMJ最新文献

{"title":"Role of Extracorporeal Shock Wave Therapy in Treatment of Plantar Fasciitis.","authors":"S Sarker, S M M Islam, S K Barua, T Uddin, M M Rahman, M A Islam, M M Rahman, A M A Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Plantar fasciitis (PF) is a common source of heel pains that affects 10.0% of the general population. This study assessed the effects of Extracorporeal Shock Wave therapy (ESWT) in terms of pain and functional outcome of foot in plantar fasciitis. The study was an experimental study conducted in Department of Physical Medicine and Rehabilitation, Dhaka Medical College and Hospital, Bangladesh from July 2019 to June 2020. Total 74 patients with unilateral PF were purposively selected and randomly allocated in Group A (ESWT group) and Group B (conventional treatment group). Heel pain intensity and the impact of foot pathology on function were measured using the Visual Analogue Scale (VAS) and Foot Function Index (FFI) respectively. The VAS scores significantly decreased from 7.36±1.18 to 1.79±1.03 in patients after treatment with ESWT (p<0.001). The reduction of VAS score was significantly more in ESWT group compared to conventional treatment group at 4th week, 12th week and 24th week (p<0.05). The total FFI scores significantly decreased from 49.33±5.64 to 17.89±5.12 in patients after treatment with ESWT (p<0.001). The FFI scores significantly decreased from 48.07±4.02 to 20.99 ±5.65 in patients after conventional treatment (p<0.001). The reduction of FFI score was significantly more in ESWT group compared to conventional treatment group at 4th week, 12th week and 24th week (p<0.05). Extracorporeal shock wave therapy (ESWT) is effective in patients with plantar fasciitis to reduce pain and improvement of functional outcome. Though conservative treatment also improves pain and function in the foot, ESWT is more effective than conservative treatment.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"738-744"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Risk Factors in Patients with Chronic Non-Specific Low Back Pain.","authors":"M A Hoque, M Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic low back pain is one of the most common causes of inactivity and chronic disability. Many risk factors have been identified as contributing to the development of chronic non specific low back pain. Several risk factors have been postulated including age, sex, posture (bending or twisting, prolonged standing), manual handling, tobacco smoking, occupation and socioeconomic factors. To determine the association between low back pain and posture, exercise, family history, level of education, level of income, smoking and others. This case control study was conducted at Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh one of the largest government referral hospital with well-established Physical medicine department along with other departments from 1st February 2015 to 31st July 201. Sixty four (64) cases (patients with low back pain) and 64 controls (patients without low back pain) were enlisted to perform this case control study. The sample size was 128. With a pre-tested structured interviewer administered questionnaire Data was depicted, investigating about demographic data and related risk factors. To calculate BMI (Body mass index), heights and weights was tailored accordingly. Age range was 30 to 60 years. The point prevalence of low backache was 63.0%. Mean age ±SD (Standard deviation) for cases was 45.48±8.5 years. Mean age ±SD for controls was mean age of controls were 47.81 years with standard deviation of 7.68 years. Back pain was significantly associated with the risk factor 'bending and twisting movements of the body' (Odds Ratio= 4.6 with 95% Confidence Intervals= 1.47 to 2.89, p= 0.043), sleeping hours <6 hours (Odds ratio=5.212 with Confidence intervals=1.212-2.966). Participants having ≤5 years of education were more common in cases (14.1%) than controls (7.8%). Illiterate participants were higher in controls (28.1%) than in cases (17.2%) and the difference was found statistically significant (p<0.05). Mean BMI was 23.05±2.68 for cases and 21.95±2.87 for controls. Overweight persons suffered more from low back pain (38.3%) than that of controls (23.4%). Persons with normal weight were higher (61.7%) in controls than in cases (48.4%). Underweight were almost equal. The differences were found statistically significant when chi-square test was performed (p<0.05). Low back pain had a high prevalence in Bangladesh. Bending and twisting movements of spine, level of education, body mass index had significant risk factors of low back pain.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"846-853"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex Determination of Human Remains Using Fingerprint Ridge Density.","authors":"S Gupta, S Kumar, J Singh, S P Mandal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fingerprint ridge density (FPRD) refers to the number of ridges within a defined area of a fingerprint. It is known to exhibit sexual dimorphism, with females generally showing finer (more densely packed) ridges than males. This cross-sectional observational study was conducted to evaluate the sexual dimorphism of FPRD and its applicability in mass casualty scenarios, where only hand or finger remains may be available for identification. Fingerprints were collected from 429 male and 50 female cadavers subjected to postmortem examination at our tertiary care institute located in the Northwest part of India from July 2016 to December 2017, by ink-impression on paper. Epidermal ridge counts were obtained within a 5 × 5 mm square area on the radial side of each fingerprint (adjacent to the core), following the method of Acree. Ridges crossing a diagonal line within the square were counted under magnification to calculate ridge density (ridges/25 mm²). Statistical analysis (including Student's t-test) was performed to compare male and female ridge density distributions. Female fingerprints showed significantly higher ridge densities than male fingerprints (mean FPRD ≈ 14.86 in females vs. 12.18 in males, p<0.001). No male fingerprint had a ridge density above 14 ridges/25 mm² and no female had below 12, yielding a practical threshold for sex differentiation. Combining all ten fingers improved accuracy: ridge counts among 10-13 indicated male origin, whereas 14-16 indicated female origin in ~99.0% of cases. The FPRD method provides a quick, cost-effective means of sex determination from fragmented remains. In disaster victim identification, a simple ridge count in a defined fingerprint area can reliably distinguish sex on the spot, aiding forensic and humanitarian efforts when DNA or other analyses are impractical.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"914-920"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Status of the Microbiological Isolates and Antibiotics Susceptibilities in Patients with Auricular Perichondritis.","authors":"M G Mostafa, M Nuruzzaman, L Khan, K Dey, B Ahmed, M K Shofi, S Gupta, M R Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Auricular perichondritis is a dangerous infection involving the external ear cartilage and its perichondrium. This condition can lead to significant morbidity including cartilage necrosis, deformity and the characteristic \"cauliflower ear\" if not properly diagnosed and treated in a timely manner. The infection typically develops following trauma, burns, insect bites, ear surgery, or ear piercings through the cartilaginous portion of the ear. Objective of the study was to analyze the microbiological profile and antibiotic susceptibility patterns in auricular perichondritis and to evaluate treatment outcomes in relation to causative organisms and therapeutic approaches. This prospective observational study of 50 consecutive cases of auricular perichondritis was conducted at Mymensingh Medical College Hospital from July 2022 to June 2023. Specimens were collected for culture and antimicrobial susceptibility testing. Patient demographics, predisposing factors, clinical presentations, treatment modalities, and outcomes were analyzed. Patients were followed up for 30 days post-treatment. The mean age was 28.3±9.7 years, with male predominance (60.0%). Ear piercing was the most common predisposing factor (56.0%). Culture positivity rate was 86.0%, with Pseudomonas aeruginosa (41.9%) and Staphylococcus aureus (27.9%) being the predominant isolates. Methicillin-resistant Staphylococcus aureus (MRSA) accounted for 11.6% of isolates. Pseudomonas (P.) aeruginosa showed high susceptibility to fluoroquinolones (88.9%) and aminoglycosides (83.3-94.4%). Complete clinical resolution was achieved in 94% of cases, with mean treatment duration of 14.2 ± 3.8 days. Delayed presentation (>3 days) significantly correlated with complications (p=0.023). The study reveals evolving patterns of causative organisms in auricular perichondritis, with a notable presence of resistant organisms. High culture positivity rates support the importance of culture-guided therapy. Treatment outcomes are favorable with appropriate antibiotic selection and timely intervention. These findings provide evidence-based parameters for empiric therapy while emphasizing the importance of microbiological confirmation.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"643-649"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Presentation of Hepatocellular Carcinoma in a Tertiary Care Hospital in Bangladesh.","authors":"M A Siddiqui, C R Debnath, G M I Hossain, C Debnath, D Debnath, S M A Haque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hepatocellular carcinoma is the most common primary liver cancer. Chronic viral hepatitis, alcohol abuse, and NAFLD are the common causes of hepatocellular carcinoma. Usually patients present at advanced stages where curative treatment is no longer possible. This study aimed to find the clinical presentation, etiology& stage at presentation among patients with hepatocellular carcinoma in a tertiary care center. This retrospective observational study was conducted in a single tertiary care center from July 2023 to June 2024. The study was done among inpatients of the Department of Hepatology. About 30 Cases were recorded with confirmed hepatocellular carcinoma over this period. Among 30 patients, 53.33% of patients were above 60 years of age and 76.66% were HBsAg positive. 90.0% of patients were symptomatic among which abdominal pain was the most common. Features of cirrhosis with hepatomegaly were the main physical findings. Normal alpha-fetoprotein levels were in 13.33% of patients; 96.66% of patients were in advanced age where curative treatment was not feasible. Hepatocellular carcinoma is a significant concern. It is crucial to identify high-risk patients, which should lead to screening using both serum alpha-fetoprotein level and ultrasonography of the liver. There is an urgent need to discover more effective treatments or other methods for managing this condition, particularly in its advanced stages.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"897-903"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial Sensitivity in Sputum among Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients.","authors":"M S Sorwer, M D J Khan, M A Rahman, U R Jahan, M A Islam, M Asaduzzaman, M A Rouf, M S A Mozahid, M R Haider, T B B Disha, M Islam, M A Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is the third common cause of death worldwide and low- and middle- income countries (LMICs) suffers 90.0% of these deaths. Natural history of COPD is characterized by many exacerbations, 50.0% of these are caused by bacteria from lower respiratory tract. Bacterial flora of acute exacerbation of COPD keeps changing from time to time and choice of antibiotic depends upon the local bacterial prevalence and resistance. Very limited data about bacteriological profile in AECOPD patients are available in Bangladesh. This cross-sectional descriptive study was conducted at Department of Respiratory medicine and Department of Medicine, Mymensingh Medical College Hospital, Bangladesh from August 2023 to January 2024 with the approval of Institutional Review Board. Sample size was 68. Bacteria were identified from sputum of 56 patients (82.4%), 44 of them are culture positive (64.7%). Gram Negative bacteria are more common (86.4%), Klebsiella is most prevalent (59.1%). Irrespective of Gram staining, most patients are sensitive to Carbapenems, Colistin, Erythromycin, Azithromycin, Linezolid and ampicillin (100.0%). Most bacteria are fully sensitive (100.0%) to carbapenems except Proteus and Acinetobacter. Klebsiella is also sensitive to Gentamycin (92.3%), Amikacin (86.4%), Ceftriaxone (76.9%) and Ciprofloxacin (61.5%)%). In case Pseudomonas Ciprofloxacin (100%), Amikacin, Gentamycin, Levofloxacin & Pip-Taz (66.7%) shows significant sensitivity. While Streptococcus shows 100% sensitivity to Amikacin, Gentamycin & Ciprofloxacin.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"691-699"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Duration of Visual Symptoms and Early Postoperative Visual Outcome Following Pituitary Macroadenoma Surgery.","authors":"M K Hossen, S Sarkar, R S Wazed, M S Hossain, S Saha, A Dasgupta, M Yesmin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pituitary tumors represent approximately 10.0-17.0% of intracranial tumors. However, they may grow large and extend into surrounding structures, resulting in neurological and hormonal complications, including visual impairment. The duration of visual involvement will help predict visual outcomes after pituitary surgery and will be helpful for patient counseling. This prospective observational study was conducted in the neurosurgery department of Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh. The patient who fulfilled the selection criteria which included (specific criteria) was enrolled in this study and was divided into two groups according to the Duration of visual symptoms. A total of 24 patients were selected; 12 presented with visual symptoms with less than six months duration; they were included in the first group and 12 patients with more than 6 months duration were included in the second group. Patient data were recorded in a predetermined data sheet. An ophthalmologist examined visual status. Data was processed and analyzed using SPSS version 22.0. An appropriate statistical test for data analysis (Chi-square test and student t-test) was performed. Statistical significance was at p-value <0.05 at a 95% confidence interval level. The age distribution of 24 patients ranged from 17-64 years, with a mean ±SD of age of 36.21±13.7. Males had slightly more preponderance than females in this series, with a male-to-female ratio 1.2:1. All patients presented with visual problems (100.0%). The majority (93.3%) patients presented with headache, 6 patients (25.0%) presented with acromegaly, 1 patient (4.2%) presented with hypothyroid and 3 patients (12.5%) presented with amenorrhea and galactorrhea. Regarding visual acuity symptoms less than 6 months, 58.3% were improved, and 41.7% were not improved. Visual symptoms of more than 6 months duration 25.0% out of 24 eyes improved and 18(75.0%) did not improve post-operatively; we found that visual symptoms of less than 6 months improved better postoperatively (p-value 0.001). This study reveals a significant association between the duration of preoperative visual symptoms and early postoperative visual outcomes in patients with pituitary macroadenoma surgery. Specifically, patients presenting with less than 6 months of visual symptoms showed a marked improvement compared to those with more than six months duration. These findings provide valuable insights for patient counseling and early intervention strategies.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"683-690"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency and Pattern of Premalignant and Malignant Lesions among Fecal Immunochemical Test Positive Patients.","authors":"C S Hyder, M A Uddin, M T Jalal, S S Karim, M A Taher, K Nahar, M S Hossain, M S H Sheikh, M S Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Colorectal cancer is a challenging clinical entity worldwide. Adenomatous polyps are considered precursors to cancer. Detection and confirmation of mucosal healing of ulcerative colitis require a colonoscopy. For early detection of polyps or ulcers, different screening investigations like colonoscopy, Fecal Immunochemistry Test, gFOBT, CT colonography, etc. are used. Though gold standard colonoscopy has both diagnostic and therapeutic roles, Fecal Immunochemistry Test can detect advanced adenoma or established cancer or mucosal status of Ulcerative colitis. The Fecal Immunochemistry Test is a less expensive technique for the early detection of colonic pathology and is suitable for our demographic. The aim of the study was to observe the frequency and pattern of premalignant and malignant lesions among Fecal Immunochemical Test (FIT) positive patients. This observational cross-sectional study was conducted from July 2019 to June 2020 among 105 Fecal Immunochemical Test (FIT) positive patients. The observational cross-sectional study was carried out in the Department of Colorectal Surgery, Bangabandhu Sheikh Mujib Medical University and some private hospitals, Bangladesh. FIT tests were done in ICDDR`B. Among 105 Fecal immunochemical test positive study patients, colonoscopy evaluations were done. Among these, 58 cases (55.2%) revealed different types of polyps. Pedunculated polyps 42(40.0%) were predominant, present in 42(40.0%) of patients. Other than polyps, there were ulcers 14(13.3%), malignant looking growth 3(2.9%), hemorrhoid 13(12.4%) and normal findings in 15(14.3%) cases. The age range was 40-70 years. The mean age was 51.73±7.97 years. Adenomatous polyps and malignancies were 47(44.7%) and 5(4.8%). Advanced adenomas were 11(10.4%) cases. Thirty six (62.1%) polyps were in the left colon. Patients with normal findings, diverticulosis and hemorrhoids had not undergone biopsy. Fecal immunochemical test (FIT) can predominantly detect adenomas, especially advanced adenoma and precursor lesions. The study finding showed that both non-neoplastic, neoplastic polyps and ulcers had occult bleeding. So, they became FIT positive. Though colonoscopy is the gold standard in the detection of polyps, ulcers, or malignant lesions, FIT can be a good supportive tool for screening.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"745-751"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Hypoparathyroidism Following Total Thyroidectomy in a Tertiary Care Hospital of Bangladesh.","authors":"M Ahmed, M A Siddique, M M Islam, M Nuruzzaman, M M Alam, M J A Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Total thyroidectomy is a common surgical procedure for MNG and thyroid malignancies with or without lymph node metastasis. Post total thyroidectomy hypoparathyroidism is not so uncommon. Understanding the prevalence of temporary and permanent hypoparathyroidism in post-total thyroidectomy is very important for improving patient outcomes. This prospective observational study was conducted in Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2023 to December 2023 where 92 cases were selected purposively who underwent total thyroidectomy for MNG and thyroid malignancy without extra thyroidal extension. The incidence of transient and permanent hypoparathyroidism after total thyroidectomy, demographic variables, and postoperative day of onset of hypocalcemia were analyzed. Data collection was done through patient records and postoperative follow-ups. This study revealed that 23.0% of patients experienced hypoparathyroidism post-operatively. Hypoparathyroidism was most prevalent among patients underwent total thyroidectomy for thyroid malignancy (47.83%) compared to those undergoing total thyroidectomy for benign thyroid disease (17.39%). The majority of hypocalcemia cases (60.87%) occurred on the second postoperative day. Among the 23 cases of postoperative hypoparathyroidism temporary hypoparathyroidism was 69.57% and permanent hypoparathyroidism was 30.43%. After total thyroidectomy Hypoparathyroidism remains a significant complication. Early identification and management of at-risk patients is necessary to reduce the severity of this complication.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"656-659"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Belief about Antibiotic Use among Rural People of Bangladesh.","authors":"M S Khan, F Karim, M R A Ovi, S Nasrin, M A Ashraf, M K Hasan, M M Rahman, S M F Hasan, M D Islam, A J Faisel, M J Hasan, M A S Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Knowledge and belief about antibiotic use are important modifiers of antibiotic-associated health practices and, thereby, its resistance. Rural people's knowledge and belief about antibiotic use and their determinants largely remained unexplored in Bangladesh. Hence, this study was aimed. This descriptive cross-sectional study was conducted between July 2016 to March 2017 in Upazila Health Complex, Matlab South, Chandpur, Bangladesh. Adult (≥18 years) residents of the study area coming for health service were approached and a total of 184 participants were selected using a systematic random sampling method. Data were collected by face-to-face interview using a pre-tested structured questionnaire including questions on knowledge and belief regarding antibiotic use. Informed verbal consent was taken before inclusion. The principles laid out by World Medical Association Declaration of Helsinki were following during all the procedures of this study. Data analysis was done in STATA© Version 16.0. The average age of the participants was 37.45±13.32 years (SD) with a female predominance (61.4%). Of all, 63.0% knew about antibiotics, and out of them 59.5% self-prescribed the drug. Among participants who knew about antibiotics 63.9% (n=73) had good knowledge and 47.8% had appropriate belief. On multivariable logistic regression, higher education (SSC and above) (OR 4.67, 95% CI 1.02 - 21.38) and use of the internet and social media (OR 8.27, 95% CI 1.51-45.33) were found to be significant predictors of good knowledge regarding antibiotic use. Moreover, belief regarding antibiotic use showed a significant positive linear association with knowledge (Spearman's rho=0.4797, p<0.001). The study found that nearly one-third of rural people had poor knowledge and more than half had inappropriate belief about antibiotic use among rural people in Bangladesh. Authorities and policymakers should urgently address the situation to resist the threat of widespread antibiotic resistance.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 3","pages":"791-800"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}