Mymensingh medical journal : MMJ最新文献

{"title":"Factors for Quitting Tobacco Consumption among the Male Bangladeshi Garments Workers: A Cross Sectional Study.","authors":"M Imamuzzaman, K F Mukta, M Ansari, S Rahman, C A Chowdhury, M S Basher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite enormous adverse effects, tobacco consumption is increasing with very little success of cessation programs. This is very important to have update knowledge regarding the factors attributed to the failed attempts for quitting tobacco consumption. The study was intended to find out the factors associated with quitting tobacco consumption among the male Bangladeshi garments workers. A descriptive cross-sectional study was carried out among 451 randomly selected workers of four purposively selected garments at Gazipur and Savar, Dhaka. After permission from the garments authorities and informed verbal consent from the selected respondents, data were collected by principal investigator using pre-tested interview schedule through face-to-face interview with privacy. After completion of each interview, questionnaire was cross-checked for completeness, consistency and discrepancy. Participants had freedom to withdraw from the study at any time without explaining any reason and data confidentiality was ensured strictly. The procedure did not have physical, mental and social risks. All other ethical issues and measures for data quality were taken into due consideration. Data were analyzed using computer software SPSS version 25.0 and presented in tables and diagrams. Nearly half 206(45.7%) of the workers were in age group 26 to 33 years with a mean of 28.85±8.03 years. Religion of 387(85.8%) respondents was Islam, while 278(61.6%) had completed secondary education. More than three-fifths 282(62.5%) of the workers were married with a mean family size of 4.24±1.44. As many as 379(84.0%) workers had monthly income less than 15000 Taka with a mean of 13212.86±1573.08 Taka. An overwhelming number 411(91.1%) of respondents started tobacco consumption within the age of 13 to 19 years with mean age of initiation of 16.18±2.67 years. Of 451 workers, 446(98.9%) made an effort to quit tobacco. Of them, for 286(64.1%) workers personal health problem was the influencing factor for quitting attempt. As many as 380(85.2%) workers preferred to quit tobacco consumption through reducing the consumption. Nearly three-fifths 264(59.3%) of workers were failed to quit due to bodily addiction. More than four-fifths 375(83.1%) workers affirmed that they could be able to quit tobacco. Nearly three-fourths 326(72.3%) workers did not consult doctor because they believed that they could do it by themselves. Over two-fifths 181(40.6%) of workers attempted for 4 to 10 times for quitting, while majority 213(47.8%) had maximum duration of abstinence for less than 1 week. It can be concluded that workers initiate smoking as teenagers. Personal health problems influence the workers in quitting tobacco. Moreover, they believed that they themselves are enough to do it without consultation with the physicians. A considerable number of workers had planned for quitting as well as attempted to do so more than once. However, all of them failed to do so due to bodily addiction.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"469-475"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total and Segmental Colonic Transit Time in Patients with Constipation Attending in Dhaka Medical College Hospital: A Case Control Study.","authors":"J M A Islam, M J Alam, M R Karim, F Ahmed, M G Kibria, M M Rahman, H Aftab, A S M Salimullah, V Nesa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Constipation is a regular medical sickness all over the world. Primary constipation may by normal transit constipation, slow transit constipation and fecal evacuation disorder. Categorization into these types is important for subsequent management. Among the methods of measurement of colonic transit time radiopaque marker study is simple and easy to perform. This case control observational study was conducted in the department of Gastroenterology, Dhaka Medical College and Hospital, Bangladesh from March 2018 to March 2019 to measure the colonic transit time of patient of constipation and to compare it with healthy control. Constipation can be sub-classified with colonic transit time. Patient of chronic constipation were divided into functional constipation and constipation predominant irritable bowel syndrome according to symptoms based diagnostic criteria. Patients with constipation underwent routine investigation including colonoscopy to exclude organic disease. Two gelatin capsules (each containing 10 radio-opaque markers) were ingested by patient at 0, 12 and 24 hours. At 36 hours from the time of taking of first dose of markers abdominal radiograph was taken to calculate retained marker and colonic transit time in each segment of colon. Colonic transit time calculated using, Colonic transit time (or segmental transit time) = 12/20 × (n) hours, where n is the sum of the markers on the X-ray film (or in the delineated segment) this formula. Healthy control undergone same procedure. Comparison of results was done using paired and unpaired 't'-test. In this study with this method, mean total Colonic transit time of healthy participant found 9.98 hours (min 1.8, max 18) and patient with constipation is 11.5 hours (min 0.0 hour, max 23.4 hour). The difference is not significant. Total colonic transit time in \"slow transit time\" patients is 22 hours (min 20, max 23.4) and 8.87 hours (min 0, max 16.2) in normal transit time patients. Segmental colonic transit of case group are right segment 4.7 hours (min 0, max 3.6), left segment 3.1 hour (min 0, max 10.2) and rectosigmoid segment 3.8 hour (min 0, max 14). The corresponding value in healthy control are 3.3 hour (0.6 min, max 7.2), 2.2 hour (min 0.6, max 4.8) and 4.3 hour (min 0, max 12) respectively. In real life colonic transit time can not be 0 hour, but with this method it can be 0, if the number retained marker is 0 then calculated colonic transit time can be 0 hour. No significant difference found between male and female, smoker and non-smoker of both groups.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"491-501"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Helicobacter Pylori in Gastroduodenal Biopsy Samples of Dyspeptic Patients by Rapid Urease Test and Polymerase Chain Reaction in a Tertiary Care Hospital of Bangladesh.","authors":"S J Ferdaus, N Haque, M R Karim, M Nadiuzzaman, N Islam, M S Alam, A Islam, M S Malek, M S Ahsan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic infection of H. pylori can cause various gastrointestinal diseases including chronic gastritis, peptic ulcer diseases, MALT lymphoma and gastric carcinoma. The study was aimed to detect H. pylori infection among dyspeptic patients in Mymensingh. Analysis was performed by Rapid urease test (RUT) and Polymerase chain reaction (PCR) and confirmed by Sanger sequencing of DNA fragments. This study cross sectional, descriptive type of observational study was conducted in the Department of Microbiology, Mymensingh Medical College, Bangladesh from March 2022 to February 2023. Endoscopic gastroduodenal biopsy samples were collected from dyspeptic patients attending at Gastroenterology department of Mymensingh Medical College Hospital, Bangladesh who fulfilled the inclusion criteria. RUT test and Polymerase chain reaction (PCR) were used for detection of H. pylori. Out of 221 samples, 80(36.19%) were considered as H. pylori positive cases whereas, 71(32.12%) cases were PCR positive and 72(32.57%) cases were RUT positive. Out of 80(36.19%) H. pylori positive cases, gastritis (65%) was the most common endoscopic finding followed by duodenal ulcer (15%), gastric ulcer (8.8%), reflux oesophagitis (8.8%), suspected gastric cancer (1.3%), normal mucosa (1.3%) respectively by any of two tests (RUT and PCR). DNA sequences of different PCR amplified product and phylogenetics analysis showed strains diversity compared to other reference sequences of H. pylori from different regions of the world. More than one third of the dyspeptic patients in Mymensingh were having H. pylori infection. This study will be helpful for understanding the current trend of H. pylori in Bangladesh.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"365-374"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Induction Chemotherapy with the Berlin-Frankfurt-Munster-95 Regimen in Acute Lymphoblastic Leukemia Patients: A Quasi-Experimental Study.","authors":"N Chowdhury, A Kabir, M M Islam, S Das, M Wasim, M N Karim, M M Alam, M N Islam, J Banik, J Fardous, M K Hassan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Response to induction chemotherapy plays a major role in prognosis of acute lymphoblastic leukemia (ALL). The objective of this study was to explore the outcome of induction chemotherapy with the Berlin-Frankfurt-Munster (BFM) -95 regimen in ALL patients admitted to a tertiary care hospital in Bangladesh. This quasi-experimental study was conducted among 50 ALL patients admitted to Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh from January 2020 to June 2020. All patients received induction therapy with the Berlin-Frankfurt-Munster-95 regimen following pre-induction prednisolone therapy. Outcomes were defined as complete remission (CR) and undetectable minimal residual disease (MRD). There was significant clinical and hematological improvement after induction chemotherapy with the BFM regimen. A total of 68.0% patients achieved complete remission. Negative MRD was achieved in 66.0% patients. In addition, 72.0% of the patients had a good response to pre-induction prednisolone therapy. Positive outcomes were not associated with the clinical presentation or disease characteristics of the ALL patients. Induction chemotherapy with the BFM-95 regimen is effective in the majority of ALL patients irrespective of clinical presentation or disease characteristics.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"412-419"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Status of Lipid Profile among Patients with Chronic Kidney Disease.","authors":"S A Mitu, M R Hoque, M Banu, M Y Mili, A T Jenea, T Z Sharmi, F R Momo, S A Mahi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic kidney disease (CKD) is an increasing threat for health-care systems in the world. Primary causes of CKD are diabetes and vascular diseases. So, optimal management of CKD includes cardiovascular risk reduction, treatment of albuminuria, avoidance of potential nephrotoxins and adjustments to drug dosing. Patients also require monitoring for complications of CKD, such as hypocalcemia, hyper-kalemia, dyslipidemia, metabolic acidosis, hyper-phosphatemia, vitamin D deficiency, secondary hyper-parathyroidism and anaemia. This cross-sectional study was executed in the Department of Biochemistry, Mymensingh Medical College, in collaboration with the Department of Nephrology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh from July 2022 to June 2023. The subjects were selected based on inclusion and exclusion criteria by purposive non-random sampling. A sum of 120 subjects was included in this study. Out of them, 60 were selected as case of CKD patients and another 60 apparently normal healthy persons were selected as control. In this study, serum lipid profile was measured for analytical study. All the values were showed as mean±SD and these were serum TC were 149.85±38.84 in Group I and 178.92±41.85mg/dl in Group II; Serum TG were 122.77±36.88 in Group I and 175.93±63.50mg/dl in Group II; Serum LDL-C were 95.13±24.43 in Group I and 115.60±45.62 mg/dl in Group II and Serum HDL-C were 48.62±8.70 and 41.55±2.79mg/dl in Group I and Group II respectively. Statistical analysis was done by using statistical package for social science (SPSS), windows package version 26.0. The statistical significance of the difference between the case and control was evaluated using Student's unpaired 't' test. After careful evaluation, the present study found that mean serum total cholesterol (TC), Triglyceride (TG) and Low density lipoprotein (LDL-C) level were significantly increased and High density lipoprotein (HDL-C) level were significantly decreased in CKD patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"338-342"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Serum Gamma Glutamyl Transferase with Gestational Diabetes Mellitus.","authors":"H Koly, T R Das, N Haque, N Hosain, M F Islam, S S Tithi, M S Bari, Y D Jannat, N J Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Gestational diabetes mellitus (GDM) is the most common metabolic disorder resulting in adverse consequences on both maternal and fetal outcome. Oxidative stress plays an important role in the pathophysiology of gestational diabetes mellitus by inducing insulin resistance in the peripheral tissue and impairing insulin secretion from pancreatic β-cell. Serum gamma glutamyl transferase (GGT) plays an important role in oxidative stress and recently it has been recognized as a marker of oxidative stress. GGT can be used as an indicator of the GDM. High level of GGT is a new risk factor for GDM, which is cheap, rapid and easily available parameter for monitoring the GDM patients. This case control study was carried out in the Department of Obstetrics and Gynecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh from May 2019 to February 2020. A total of 76 pregnant women were enrolled in this study, out of which 38 women with GDM was considered as Group A and rest 38 women with normal pregnancy was considered as Group B. Gamma glutamyl transferase concentration was measured in all the study subjects. Statistical analysis of the results was obtained by using Microsoft Excel and Statistical Packages for Social Sciences (SPSS-22.0). The mean GGT was 25.0±7.46U/L with ranged from 13-41U/L in Group A and 12.95±3.23U/L with range from 7-19U/L in Group B. The difference was statistically significant between two groups. A positive significant Pearson's correlation was found between FBS and GGT in Group A. There was also positive significant Pearson's correlation found between 2 hours ABF with GGT in Group A. In Group A serum GGT level >16U/L had 4.42 times significantly increased to develop GDM. GGT was higher in GDM group than normal pregnancy. Monitoring GGT levels in pregnancy may help to identify women with increased risk of developing GDM.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"502-508"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Quality Assurance Scheme of Government Medical Colleges of Mymensingh Division.","authors":"U J Ferdaus, M K Khan, J Ferdous, P Das, M N Hossain, M S Ameen, A Rahman, M A Hossain, M Ferdous, R Yeasmin, N Sultana, A A Mamun, I Hossain, S Paul, T B Faruk, M A Panna","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Maintaining quality assurance is among the most critical things the medical education system has to do. Quality control can be controlled by institutional monitoring, which should include course evaluation, peer review and assessment. This study was designed to assess the status of the quality assurance scheme of government medical colleges of Mymensingh division. This cross-sectional descriptive type of observational study was conducted in the Mymensingh Medical College (MMC), Mymensingh; Jamalpur Medical College (JMC), Jamalpur and Netrakona Medical College (NMC), Netorkona, Bangladesh for one year from January 2023 to December 2023. All departments in Mymensingh Medical Colleges were optimal where some vital department was not present in JMC and NMC, such as virology, neurology, physical medicine, gastro-enteroloy, endocrinology, hematology etc. All 3 medical colleges had ongoing Quality Assurance Scheme MMC had no committee meeting in last 12 months, JMC and NMC had committees meetings held three in all phases. A good percentage of students had passed all professional examinations in last year in these 3 medical colleges. All 3 medical colleges had pair Colleges had Pair College with each other. In MMC and JMC had gone through the external review visit and also these two had faculty members fill up personal review form. Medical Education Unit (MEU) was established in MMC and JMC, but no MEU was established in NMC. All 3 medical colleges had annual sports, indoor-outdoor games and annual cultural program. The current status of the quality assurance scheme of MMC is optimal, whereas other medical colleges need to be improved. All three government medical colleges of Mymensingh division had ongoing quality assurance schemes including student performance, external reviews, faculty development, co-curriculum and extra-curriculum activities.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"324-330"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Efficacy of Bivalirudin in Female Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention.","authors":"A B M Mostofa, K K Karmoker, R Afrin, A Hossain, A Alam, B Dutta, T Parvin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Being women is an independent predictor of adverse events during percutaneous coronary intervention (PCI). Whether newer anticoagulant bivalirudin is safe and effective in female acute coronary syndrome (ACS) patients undergoing PCI, as compared with conventional heparin, is less well defined in Bangladeshi population. Our aim was to evaluate safety and efficacy of Bivalirudin in female ACS patients undergoing PCI. One hundred (100) female ACS patients were enrolled in this randomized controlled study, which underwent PCI from May to November, 2019 at BSMMU. Among them 35 patients were randomly assigned to receive bivalirudin and 65 patients were in control group to receive heparin with or without eptifibatide (GPI, glycoprotein IIb/IIIa inhibitor). The outcome measures were incidence of 30-day hemorrhagic complications, stent thrombosis and major adverse cardiac and cerebral events (MACCEs). Bivalirudin treatment was associated with significantly lower incidences of 30-day net adverse clinical events (NACEs) (5.7% vs. 27.6%, p=0.009) and bleeding (2.8% vs. 16.9%, p=0.03) compared with the control regimen. The incidence of MACCEs (2.8% vs. 15.4%, p=0.05) and stent thrombosis (0.0% vs. 3.1%, p=0.295) were comparable between the two groups. Multivariate analysis showed that bivalirudin (OR: 0.264, 95% CI: 0.071-0.977, p=0.04), trans-radial access (OR: 0.056, 95% CI: 0.003-0.967, p=0.04) and statin (OR: 0.009, 95% CI: 0.0005-0.168, p=0.001) were independent protective factors for 30-day NACEs. Bivalirudin is safe and effective in female ACS patients undergoing PCI as it reduces hemorrhagic complications without increase ischemic events (MACCEs) as compared with conventional heparin.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"545-553"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Vitamin D₃ Supplementation Improve Cardiac Autonomic Nerve Function in Vitamin D₃ Deficient Asthma COPD Overlap (ACO) Patients? A Randomized Clinical Trial.","authors":"S M Yesmin, S Sultana, S Ferdousi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cardiac autonomic nerve dysfunction has been found associated with chronic obstructive pulmonary disease (COPD) patients as well as vitamin D₃ deficient patients. Heart rate variability (HRV), one of the markers of cardiac autonomic nerve function which is reduced in Asthma COPD overlap (ACO) patients. Sympathovagal balanced was improved in healthy subjects after administration of vitamin D₃. This randomized clinical trial aimed to observe the therapeutic effect of vitamin D₃ supplementation on non linear measures of HRV in 60 male vitamin D₃ deficient (<30 - 10 ng/ml) ACO patients. Patients were given orally either vitamin D₃ capsule or placebo per week for 6 months and serum vitamin D₃ level and non linear measures of HRV were assessed before and after intervention. HRV was measured by power lab 8/35, AD instruments and vitamin D₃ was assessed by chemiluminescent micro-particle immunoassay (CMA) method by auto analyzer. For statistical analysis paired sample 't' test and independent sample 't' test were done. Before intervention vitamin D₃ level and non linear parameters of HRV were similar in all patients but both these outcome measures significantly increased in vitamin D₃ treated but not in placebo treated patients after 6 months. In conclusion, vitamin D₃ supplementation is effective to improve HRV in vitamin D₃ deficient ACO patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"530-537"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-seeking Behavior and Diagnostic Delay of Systemic Lupus Erythematosus in Patients of Bangladesh: A Hospital-Based Cross-Sectional Study.","authors":"A M Ahammad, M N Islam, S Yesmin, S Islam, J Fardous","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Patients with systemic lupus erythematosus (SLE) often ignore the initial symptoms of the disease and delay in seeking medical care, which ultimately prolongs the diagnostic delay. The objective of the present study was to explore the health-seeking behavior and the factors associated with diagnostic delay in SLE patients. This cross-sectional study was conducted among 85 patients suffering from SLE who attended the Lupus Clinic of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from January 2012 to June 2013. Socio-demographic and disease-related data were collected by face-to-face interviews. Diagnostic delay was defined as the period of time from onset of initial symptoms of SLE and confirmation of diagnosis. Factors associated with diagnostic delay were determined by appropriate statistical test. Almost 75.0% of the patients visited qualified physicians and their average interval of seeking medical care after the onset of SLE symptoms was 1.4±2.6 months. The average interval between the onset of initial symptoms and the diagnosis of SLE was 12.3 (SD 13.9) months. It was longer in female patients (13.2 months versus 7.3 months in male). Early medical contact and visiting qualified physicians also shortened the diagnostic delay of SLE. Patients presenting with joint pain and fever had a longer diagnostic delay than those who presented with oral ulcers, malar rash and lupus nephritis. Patients' health-seeking behavior, such as delayed medical care seeking, as well as presenting with nonspecific symptoms, such as fever and joint pain, which mimic other diseases, increases the diagnostic delay in SLE patients. These symptoms should be considered for the evaluation of immunological evidence of SLE.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 2","pages":"461-468"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}