Mymensingh medical journal : MMJ最新文献

{"title":"Relation of Iron Deficiency with Simple Febrile Seizures.","authors":"B K Banik, T B Belayet, M A Ali, B Chowdhury, N Kar, F Fahmin, S Jahan, M Amin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Febrile seizure (FS) is the most common seizure disorder in early childhood, affecting approximately 2.0-5.0% of children aged 6-60 months. The peak incidence of FS occurs between 14 and 18 months of age, which coincides with the highest prevalence of iron deficiency anaemia (IDA) in children aged 1-2 years. This study aimed to evaluate the association between iron deficiency and simple febrile seizures. A cross-sectional comparative study was conducted in the Department of Paediatrics, Mymensingh Medical College Hospital, from September 2018 to February 2020. The study included 150 children aged 6-60 months: 75 children with simple febrile seizures (case group) and 75 febrile children without seizures (control group). Detailed clinical history, risk factors and physical examinations were recorded. Haematological investigations- including haemoglobin level, serum iron, serum ferritin, total iron-binding capacity (TIBC) and red cell distribution width (RDW)- were performed to assess iron status. Data were analyzed using appropriate statistical methods, with p-values <0.05 considered statistically significant. The mean age of cases and controls was 15.59±6.63 months and 18.28±12.16 months, respectively. Male predominance was observed in both groups. Mean haemoglobin, serum iron and serum ferritin levels were significantly lower in the case group compared with controls, while TIBC was significantly higher among cases (p=0.001). RDW showed no significant difference between groups. Iron deficiency (48.0% vs. 21.3%) and iron deficiency anaemia (41.3% vs. 13.3%) were significantly more common in children with simple febrile seizures (p=0.001). The study demonstrates a significant association between iron deficiency and simple febrile seizures, suggesting that iron deficiency and IDA may be important risk factors for febrile seizures in young children.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1014-1020"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hereditary Spastic Paraplegia Type 11: A Comprehensive Case Report.","authors":"S H Siddik, T S Sumaiya, M Foysal, M H Mridul, Z Tasnim, R Das, S S Hasan, M A Islam, M M Rahman, M Monsur, M Rahman, P Debnath, M Imran, D Debnath","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hereditary spastic paraplegia (HSP) is a heterogeneous group of genetically determined diseases, characterized by progressive spastic paraparesis of the lower limbs, associated with degeneration of the corticospinal tract and the posterior column of the spinal cord. Currently known to be about 70 genes are involved in HSP, though new potentially pathogenic variants are being reported regularly. Almost all patterns of inheritance like autosomal dominant, autosomal recessive, X-linked, and mitochondrial have been found in families of HSP patients. However, autosomal recessive form, hereditary spastic paraplegia type 11 is the most common one. We presented a case of an 18-year-old woman, with no significant medical history and without known consanguinity, presented with a 2-year history of sub-acute onset and slowly progressing weakness and stiffness in both lower limbs and difficulty in walking and finally diagnosed as a Hereditary Spastic Paraplegia 11. Genetic analysis by whole-exome sequencing on the Illumina Novaseq 6000 NGS Platform was done and indicated homozygous variations in exon 4 of gene SPG11(chr15:g.44657230_44657231delAT): the c733_734del p (Met245ValfsTer2) variant on the allele. Here, we describe the clinical, radiological, and genetic presentation of Spastic paraplegia 11 (SPG11) through a report of a case and compare it with previously reported SPG11 cases in the literature.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1317-1321"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Serum Folate Status and Cervical Intraepithelial Neoplasia.","authors":"R R Sarker, J Ferdous, S Yeasmin, S Rahman, C Saha, B K Tarafder, T Nazneen, M M Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cervical intraepithelial neoplasia (CIN) is a premalignant lesion of cervix and if left untreated can progress to invasive cervical cancer after several years. Approximately 1.0-2.0% women have CIN II⁺ each year. Folate and vit B12 play important roles as inhibitors of human carcinogenesis in several organs. This study was done to evaluate the association of serum folate level with cervical intraepithelial neoplasia. This was a case control study conducted at colposcopy clinic of Bangladesh Medical University, Bangladesh. One hundred and twenty-two women were included in the study by purposive sampling from October 2019 to September 2020 after getting institutional review board approval. Study population were VIA positive women who were referred for colposcopy at colposcopy clinic of Bangladesh Medical University (BMU), Dhaka, Bangladesh. After getting informed consent, colposcopy and histopathological examination was done in all subjects irrespective of colposcopy result. Cases (n=61) were assigned to those who had histopathologicaly confirmed CIN. Control groups (n=61) were those who had both colposcopicaly and histopathologicaly normal cervix. Both groups were matched in relation to age, age at marriage, age at first delivery, parity and duration of OCP use. Serum folate level was measured in both cases and controls. Data were analyzed using SPSS software version 22. Continuous variables were expressed by mean±SD. Qualitative variables by percentage. Association of folate status and cervical intraepithelial neoplasia were assessed by unpaired 't' test, ANOVA test, Chi-Square test and in odds ratio with 95% CI. Cut off value for low serum folate level was obtained from ROC curve and it was <7.65 ng/ml. Among 61 cases of CIN, 55.0% were CIN I (n=34), 13.0% were CIN II (n=8) and 31.0% (n=19) were CIN III and carcinoma in situ. Statistically significant difference was found (p<0.05) in mean serum folate level between two groups. Among cases it was 9.74±3.51ng/ml and among controls 12.09±5.05 ng/ml, p=0.003s. Using multivariate logistic regression model serum folate <7.65ng/ml was found independently associated with CIN (OR 1.671 95% CI 1.16-2.40, p=0.039s). Low serum folate level was significantly associated with cervical intraepithelial neoplasia. So oral supplementation of folic acid to young adolescent girls and women of reproductive age may be considered to reduce the risk of developing CIN and subsequently cervical cancer.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1225-1233"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Robustness Index and Product Index of Dry, Adult Human Clavicle in Bangladeshi population.","authors":"R Ara, M A R Bhuiyan, R Ara, S Tanzeem, S Bhuiyan, A Alim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The clavicle is morphologically a modified long bone of upper limb and is also an important bone for transmission of body weight from upper limb to the axial skeleton, for muscle attachment and is a significant source of bone grafting. The basic framework of human body is reflected in bones and may provide valuable information about the biological identity of the deceased which can be used for forensic anthropological perspectives. Biological sex determination is one of the most important determinations to be made from human remains and is an essential first step in the development of the biological profile in forensics, anthropology and bioarcheology. The study which was descriptive cross-sectional in nature was done among 150 (65 right and 85 left) fully ossified and dried human clavicle in Mymensingh Medical College, Bangladesh from January 2020 to December 2020. Non-random purposive sampling technique was applied for sample collection from Department of Anatomy of Mymensingh Medical College and Community Based Medical College, Bangladesh, Mymensingh. The parameters were robustness index and product index; a ratio in which the baseline data were collected by the help of flexible measuring tape and rigid osteometry board. The robustness index is the percentage ratio between the mid clavicular circumference and straight length of clavicle whereas the product index is the inverse percentage ratio of robustness index. The mean ±SD robustness index of 65 right sided clavicles were 24.94±2.66 and 85 clavicles of left side were 25.02±2.41 whereas in case of product index it became 404.86±47.28 for 65 right sided clavicles and 403.29±38.77 for 85 left sided clavicles.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1211-1215"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of Rhinoentomophthoromycosis in a 55 Years Old Male: A Case Report.","authors":"S A Shawrave, S J M Zoheb, G I Galib, R Z Tanni, M M R Shawon, M J T Bhuiyan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Entomophthoromycosis is a chronic fungal infection characterized by a diverse range of manifestations, including subcutaneous, mucocutaneous and visceral infections. The majority of subcutaneous infections caused by entomophthoralean fungi are attributed to Basidiobolus spp, C. coronatus or C. incongruous. In this report, we present a case of rhinoentomophthoromycosis in a middle-aged, immunocompetent male, primarily affecting the nasopharynx. Initially, the diagnosis posed a dilemma, but it was ultimately confirmed through meticulous examination of microscopy and histopathology of the aspirate. The patient's response to antifungal therapy was favorable. We hereby provide a comprehensive account of this case and discuss the efficacy of Posaconazole in the treatment of rhinoentomophthoromycosis in a 55-year-old male patient with diabetes.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1312-1316"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near-Hanging Incidents and Suspected Spinal Cord Injuries: A 5-Year Analysis in a Developing Nation.","authors":"T Uddin, M T Islam, A Tasnim, M A Rahman, M A Haque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Survivors of hanging who reach hospital alive, commonly referred to as \"near-hanging\". The characteristics and outcomes of patients with suspected spinal cord injury (sSCI) following near-hanging remain poorly described in developing-country settings. The study aims to describe the demographic and clinical characteristics, temporal patterns, and outcomes of patients presenting after near-hanging with documented sSCI, while distinguishing neurological manifestations from associated neck soft-tissue and airway injuries. This retrospective multicenter observational study reviewed medical records of patients admitted following sSCI to six tertiary-care hospitals between 2018 and 2022. Demographic characteristics, reported intent, clinical manifestations, associated neck/airway symptoms, and outcomes were extracted from medical records. Where feasible, patients or their families were subsequently contacted by telephone to verify and supplement the available information. A total of 597 patients with sSCI were included. Females constituted 64.7% and 62.0% were aged 18-30 years; the mean age was 23.5±9.2 years. Most cases (94.8%) were reported as suicidal attempts, while 4.2% were reported as accidental hanging; the remainder had other or undocumented intent. Neck and upper-airway symptoms were common, with approximately 65% reporting throat pain and/or voice changes. In contrast, limb weakness, suggestive of neurological involvement, was reported in 7.24% of patients. Overall, 82.0% were documented as having recovered without reported sequelae. The highest number of cases occurred in 2020, with variation in monthly presentations during the study period. Neck soft-tissue and upper-airway symptoms were considerably more common than reported limb weakness, suggesting that clinically apparent neurological impairment affected a relatively small proportion of the cohort. The observed temporal variation may not be interpreted as evidence of a causal relationship with the COVID-19 pandemic. Standardized neurological, cervical spine, and airway assessment, together with timely rehabilitation evaluation, may help identify patients requiring ongoing care.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1141-1148"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Observational Study of Risk Factors and Fetomaternal Outcomes in Placenta Previa.","authors":"M Siddika, M N Islam, M S Khatun, S Sen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Placenta previa, a major cause of antepartum hemorrhage, results from abnormal placental implantation over or near the cervical os. It is associated with risk factors such as prior cesarean section, multiparity and advanced maternal age, contributing to significant maternal morbidity and adverse perinatal outcomes. To evaluate the risk factors associated with placenta previa and to assess its maternal and fetal outcomes among affected pregnancies. This cross-sectional study was conducted at Community Based Medical College, Mymensingh, Bangladesh from January 2025 to December 2025, including 35 ultrasound-confirmed placenta previa cases with gestational age >28 weeks. Data on risk factors and fetomaternal outcomes were analyzed using SPSS v27.0, with p<0.05 considered statistically significant. Among 35 cases, multiparity (n=26) (74.29%) and previous cesarean section (n=16) (45.71%) were the leading risk factors. Most cases occurred at 34-37 weeks (n=17) (48.57%). Type 3 placenta previa was most common (n=12) (34.29%). Cesarean delivery predominated (n=32) (91.43%), with 30 live births, 2 intrauterine deaths and 9 NICU admissions. Antepartum hemorrhage was the most frequent complication (n=18) (51.43%), followed by transfusion (n=13) (37.14%). Uterine artery ligation was the most commonly performed procedure (n=26) (74.29%), with hysterectomy in (n=4) (11.43%) cases. Placenta previa causes significant fetomaternal morbidity, mainly linked to multiparity and prior cesarean section. It commonly occurs in the late preterm period with partial and marginal types. Cesarean delivery is preferred, while hemorrhage remains the main complication requiring timely multidisciplinary management.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1075-1081"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intermittent Pneumatic Compression in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial.","authors":"F Newaz, S M Ahmed, M I Hasan, M S Rahman, A N M Nur","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphedema as a result of curative surgery for breast cancer can lead to long term morbidity. Lymphedema following post-radical mastectomy causes family and social problem of young individual. Manual-lymphatic-drainage (MLD), IPC (Intermittent pneumatic Compression), MLB (Multi-layered-bandage) and compression sleeves are main treatment stream along with medication and modification of Activities of Daily Living (ADL). The aim of this study was to evaluate the effects of intermittent pneumatic compression (IPC) alone or in combination with exercises on upper limbs circumference and hand function. Subjects were required to have mild to moderate unilateral upper limb lymphedema acquired as a result of curative cancer surgery. The study population consisted of 21 patients with breast cancer-related lymphedema. One group received IPC for 45 minutes per session at 50-60mmHg, 5 sessions per week for 3 weeks (15 sessions in total), combined with physical exercise, and the other group received physical exercise only. Before and after arm circumference measurement done at six sites on affected limb. Hand function was assessed at six months with the DASH (Disabilities of Arm Shoulder and Hand) clinical questionnaire. Both groups exhibited a reduction in upper limb circumferences after the therapy in comparison to the initial values. The reduction reached statistical significance at most measurement levels in the group that received combined IPC and exercise. Intermittent pneumatic compression is an effective method of reducing post-mastectomy lymphedema. The exercises did not have a significant effect on function of hand.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1216-1224"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical versus Ultrasonographic Axial Length Measurement before Cataract Surgery: A Comparison across Short, Normal and Long Eyeballs.","authors":"R J Munjifa, M A H Akhanda, M R Islam, F Q S Chowdhury, A Y M Hasan, M H Rahman, S M Hasanuzzaman, N K Basak, T Akhter, F Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Inaccurate biometry results can cause the worst postoperative visual outcome. An error of 1mm in the axial length measurement causes a refractive error of 2.5 D in an average eye of 23.5 mm, 1.75 D in 30 mm and 3.75 D in a 20 mm eye. The difference is much more in very short eyes. Now the result of this study will guide our clinicians to get a better biometry result in the case of short, normal and long eyeballs. The study was conducted to compare the difference in axial length measurement done by A-scan ultrasonogram and IOLMaster 700 before cataract surgery among short, normal and long eyeballs. This was a cross-sectional type of observational study. The study was conducted purposively among the age-related cataract patients admitted into the department of Ophthalmology, Mymensingh Medical College and Hospital, Bangladesh from April 2019 to March 2022. Eyeballs were categorized according to axial length as short, normal and long. Among the subgroups, axial length in short eyeballs was <22mm, normal eyeballs were 22-24mm and long eyeballs were >24mm. A total of 254 eyes of 254 age-related cataract patients were included in this study. The mean age of the total study patients was 62.32±8.48 years. A maximum of 51.6% of patients belonged to age 60-69 years and a minimum of 80-89 years. Among the study population, 50.4% of the patients were female and 49.6% of the patients were male. Eyeballs were categorized according to AL as short in 33(13.0%), normal in 196(77.2%) and long in 25(9.8%) patients. For short eyes, the mean±SD of AL measured with A-scan and IOLMaster were 21.27±0.48 mm and 21.68±0.41 mm respectively with a mean difference of 0.42±0.26 mm. For normal eyes, mean±SD AL measured with A-scan and IOLMaster was 22.66±0.45 mm and 23.04±0.48 mm respectively with a mean difference of 0.38±0.22 mm. For long eyes, mean±SD AL measured with A-scan and IOLMaster was 24.20±0.28 mm and 24.43±0.37 mm respectively with a mean difference of 0.23±0.42 mm. Among 254 patients, the mean±SD AL with A scan and IOLMaster was 22.63±0.82 mm and 23.00±0.80 mm respectively with a mean difference of 0.37±0.26 mm. The AL measured by IOLMaster was significantly more accurate (p= <0.001) than that measured by A-scan among all the subgroups as well as total eyeballs. The analysis showed good agreement between IOLMaster and A-scan. Axial length measurement by IOLMaster was more than A scan with a statistically significant difference (p= <0.001). The difference was more in short eyeballs and less in long eyeballs than normal. A correction factor of 0.37 mm can be added to A-scan ultrasonogram to get near-accurate axial length like optical biometry.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1188-1195"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Antibody Response to Hepatitis B Vaccination in Hemodialysis Patients.","authors":"R D Gupta, P K Dutta, M A Islam, R K Saha, S Dutta, S R Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>End-stage renal disease (ESRD) patients receiving maintenance hemodialysis are at high risk of hepatitis B virus (HBV) infection and demonstrate inadequate immune response to vaccination. The objective of the study was to assess the antibody response (anti-HBs levels) of hepatitis B vaccinated maintenance hemodialysis patients. This cross-sectional observational analytical study was conducted at Marine City Medical College Hospital, Chittagong, Bangladesh for 34 months of period among 50 patients receiving maintenance hemodialysis for more than 4 months. Demographic and clinical data were collected and post-vaccination anti-HBs titers were measured. Patients were classified as high responders (anti-HBs ≥100 mIU/ml), poor responders (anti-HBs ≥10 to <100 mIU/ml) and non-responders (anti-HBs <10 mIU/ml). The mean age of participants was 52±10 years; 60.0% were male. The mean duration of dialysis was 19.7±7.7 months. The common causes of ESRD were diabetic nephropathy (58.0%), glomerulonephritis (24.0%), hypertension (12.0%) and others (6.0%). Overall, 38.0% were high responders, 26.0% poor responders and 36.0% non-responders, seroconversion rate was 64.0%. Mean anti-HBs titers were 663±463 mIU/ml in high responders, 31.55±23.24 mIU/ml in poor responders and 3.23±1.98 mIU/ml in non-responders. Age >50 years, presence of diabetes mellitus and lower serum albumin were significantly associated with poor or non response (p<0.05). Development of protective antibody levels after hepatitis B vaccination in maintenance hemodialysis patients was inadequate. Older age, diabetes and low serum albumin were important predictors of poor response. Strategies such as booster dosing and revaccination may improve seroconversion rates in this population.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1060-1066"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}