Assessment of the Change of Blood pressure, Serum Total Cholesterol in Post Menopausal Women.

Abstract

Menopause is a natural process which is characterized by the permanent stoppage of menstrual period. It happens in women due to decrease of estrogen level at the ages of 45-55 years. The efficiency of life is disturbed because of imbalance of estrogen hormone such as irritability, night sweats, vaginal dryness, hot flushes, depression, sleep disturbance, headache etc. This cross-sectional analytical type study was done to evaluate the changes of blood pressure and serum total cholesterol levels in postmenopausal women in comparison to reproductive women and it was carried out in the Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh from January 2023 to December 2023. Among 200 healthy women, one hundred (100) female subjects were taken as control group (Group I) age ranges from 25-45 years and one hundred (100) female subjects were taken as study group (Group II) age ranges from 45-65 years. By indirect auscultatory method with an aneroid sphygmomanometer blood pressure was calculated and by enzymatic colorimetric method the serum total cholesterol level of the individual was measured. Output were expressed as mean±SD and by using unpaired students' 't' test, statistical significance of difference among the group was calculated. The mean ±SD of systolic blood pressure of Group I and Group II were 117.30±7.26 mm of Hg and 130.95±10.89 mm of Hg respectively and diastolic blood pressure of Group I and Group II were 76.65±5.03 mm of Hg and 85.20±6.43 mm of Hg respectively. In the study group the mean±SD of Blood Pressure is notably increased in comparison with control group. The mean±SD of serum total cholesterol level of Group I and Group II were 182.30±38.25 mg/dl and 217.63±55.53 mg/dl respectively. In the study group the mean±SD of serum total cholesterol level was markedly increased in comparison with control group. Postmenopausal women with higher Blood Pressure and serum total cholesterol level caused by lower level of female sex hormone specially estrogen hormone increased the change of cardiovascular disease, stroke, chronic renal failure, type-2 diabetes mellitus, insulin resistance and metabolic syndrome. So assessment of this parameter is important for early detection and prevention of complication related to higher Blood Pressure and serum total cholesterol level for leading a healthy life.