Association of Depressive Symptoms with Glycemic Control and Diabetic Complications in Patients with Type 2 Diabetes Mellitus: A Facility-Based Cross-Sectional Study in Bangladesh.

Abstract

Comorbid depressive symptoms in diabetic patients may be associated with metabolic deterioration. The objective of this facility-based cross-sectional study was to determine the prevalence of depressive symptoms and their association with glycemic control and diabetic complications among patients with type 2 diabetes mellitus (T2DM) in Bangladesh. This study was conducted among 350 patients with type 2 diabetes mellitus attending the outpatient department of the Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka Bangladesh, from July 1, 2021 to July 31, 2021. The prevalence of depressive symptoms was 31.0% (mild 10.0%, moderate 12.0%, moderately severe 5.1% and severe 4.0%). In the logistic regression model, age (aOR 1.11, 95% CI 1.01-1.22), female sex (aOR 2.47, 95% CI 1.22-5.00), rural residence (aOR 3.42, 95% CI 1.82-6.45), single living (aOR 7.34, 95% CI 5.51-9.63), poor glycemic control (aOR 2.59, 95% CI 1.31-5.12) and cardiovascular complications (aOR 4.17, 95% CI 1.36-12.78) were independent predictors of depressive symptoms among T2DM patients. The findings observed from this study support an association between depressive symptoms and poor glycemic control as well as cardiovascular complications of diabetes.