Correlation of Fasting plasma glucose and Serum total cholesterol in Female with Type 2 Diabetes Mellitus.

Abstract

One of the most catastrophic non-communicable diseases in the world is type 2 diabetes mellitus (DM). It results in financial loss, incapacity, and death. Fasting blood sugar is one of the diagnostic criteria for type 2 diabetes. Cholesterol is necessary for overall health but high cholesterol can be harmful leading to atherosclerotic disease. This study intended to determine the relationship between fasting plasma glucose and serum total cholesterol in patients with type 2 diabetes in the Mymensingh locality. This cross-sectional analytical study was carried out in the department of Physiology, Mymensingh Medical College, Bangladesh, from July 2023 to June 2024. A total 200 subjects age ranged from 30-65 years were selected and from them 100 were grouped as Control group, Group I (female without diabetes) and 100 were grouped as Study group, Group II (female with diabetes). The data were calculated and analyzed by using SPSS version 26. Laboratory analysis of fasting plasma glucose was done by GOD-POD method and serum total cholesterol by CHOD-POD method. Data were expressed in mean±SD and statistical significance of difference among the groups were calculated by unpaired Students 't' test. Correlation of serum total cholesterol with fasting plasma glucose was done by Pearson's correlation coefficient test. The mean value of fasting plasma glucose of control group and study group were 4.94±0.24 and 8.40±0.91 mmol/L respectively. The mean value of serum total cholesterol in control group and study group were 164.28±15.88 and 225.89±16.69 mg/dl respectively. In study group both values were significantly increased than control group. Fasting plasma glucose was positively correlated with serum total cholesterol. By this study we founded significant correlation of fasting serum glucose and serum total cholesterol in female with type 2 diabetes mellitus.