Journal of neurosurgery. Case lessons最新文献

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Late recurrence of cervical spine chordoma: illustrative case. 颈椎脊索瘤晚期复发:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-22 DOI: 10.3171/CASE25337
Connor Dolan, Suzanne Powell, Bin S Teh, Sean Barber
{"title":"Late recurrence of cervical spine chordoma: illustrative case.","authors":"Connor Dolan, Suzanne Powell, Bin S Teh, Sean Barber","doi":"10.3171/CASE25337","DOIUrl":"10.3171/CASE25337","url":null,"abstract":"<p><strong>Background: </strong>The authors report the case of a 65-year-old male with a 22-year delayed recurrence of a spinal chordoma. The patient originally underwent resection of a C4-5 chordoma in 2001 in Boston followed by proton beam radiotherapy.</p><p><strong>Observations: </strong>In August 2023, the patient presented with neck pain, shoulder pain, urinary frequency, and increased mechanical falls and was found to have a recurrence of chordoma. He underwent an anterior cervical corpectomy from C3 to C6, followed by C2-T2 posterior fusion and stereotactic body radiotherapy (SBRT). As of October 2024, there are no suspicious lesions or suspicious uptake on PET CT.</p><p><strong>Lessons: </strong>The case is notable due to the extreme length of time between the initial resection and the recurrence. The frequency of follow-up imaging is determined by how complete the resection was, but in general, chordomas should be imaged every 6 months for the first 5 years. After 5 years, annual MRI for at least 15 years is recommended by the Chordoma Foundation. However, this case shows that recurrence can occur later than 15 years, suggesting that annual MRI with and without contrast for the duration of life may be more prudent to detect late recurrence. https://thejns.org/doi/10.3171/CASE25337.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic carotid artery dissection and occlusion caused by repetitive mechanical stress to the neck while carrying a mikoshi (portable shrine): illustrative case. 外伤性颈动脉剥离和闭塞引起的颈部重复机械应力时,携带mikoshi(便携式神龛):说明案例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-22 DOI: 10.3171/CASE25488
Arisa Sato, Hiroyuki Ikeda, Natsuki Akaike, Shohei Yoshida, Takuya Osuki, Masanori Kinosada, Minami Uezato, Yoshitaka Kurosaki, Masaki Chin
{"title":"Traumatic carotid artery dissection and occlusion caused by repetitive mechanical stress to the neck while carrying a mikoshi (portable shrine): illustrative case.","authors":"Arisa Sato, Hiroyuki Ikeda, Natsuki Akaike, Shohei Yoshida, Takuya Osuki, Masanori Kinosada, Minami Uezato, Yoshitaka Kurosaki, Masaki Chin","doi":"10.3171/CASE25488","DOIUrl":"10.3171/CASE25488","url":null,"abstract":"<p><strong>Background: </strong>Traumatic carotid artery dissection can be caused by mechanical stress to the neck. The authors present a case of carotid artery dissection and occlusion caused by repetitive mechanical stress to the neck while carrying a portable shrine (mikoshi) during a traditional Japanese festival.</p><p><strong>Observations: </strong>A 41-year-old man with no significant medical history developed right hemiparesis and global aphasia while carrying a mikoshi during a festival. Imaging revealed left internal carotid artery occlusion, for which he underwent endovascular treatment. Because the occlusion was caused by dissection, carotid artery stenting was performed. The patient supported the mikoshi's carrying pole by tilting his neck to the left and clamping it between his neck and shoulder. He repeatedly bounced the mikoshi up and down on his left shoulder while carrying it, which likely caused repetitive mechanical stress to the carotid artery, ultimately resulting in dissection and occlusion.</p><p><strong>Lessons: </strong>Carrying something on the shoulder can cause carotid artery dissection and occlusion. Therefore, care should be taken to avoid placing continuous mechanical stress on the neck while carrying objects. https://thejns.org/doi/10.3171/CASE25488.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of intentional compressed placement of flow diverter stent for improvement of operative results against internal carotid artery and posterior communicating artery bifurcation aneurysms: patient series. 有意压缩置放分流支架改善颈内动脉及后交通动脉分叉动脉瘤手术效果的疗效:患者系列。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-22 DOI: 10.3171/CASE25430
Ryuzaburo Kanazawa, Noboru Kuniyoshi
{"title":"The efficacy of intentional compressed placement of flow diverter stent for improvement of operative results against internal carotid artery and posterior communicating artery bifurcation aneurysms: patient series.","authors":"Ryuzaburo Kanazawa, Noboru Kuniyoshi","doi":"10.3171/CASE25430","DOIUrl":"10.3171/CASE25430","url":null,"abstract":"<p><strong>Background: </strong>Internal carotid artery and posterior communicating artery bifurcation aneurysms (ICPC ANs) have a relatively high recurrence rate. The authors report 8 cases in which good results without coil compaction were confirmed during the follow-up period by using a small number of coils followed by flow diverter (FD) stent placement.</p><p><strong>Observations: </strong>The mean maximum aneurysm diameter in the 8 cases was 8.7 ± 4.1 mm, the mean number of coils used was 1.5 ± 0.9, and the average volume embolization rate was 14.7% ± 9%. In 6 of the 8 cases, no coil compaction was observed 1 year after treatment compared with the end of procedure, and in 2 cases, the coil shape changed in a way that preserved the origin of the fetal-type posterior communicating artery, and no compaction was observed within the aneurysm. Complete embolization was achieved in 7 of 8 cases; 1 case, in which direct oral anticoagulant was used, had a neck remnant, but no aneurysm enlargement or significant compaction was observed.</p><p><strong>Lessons: </strong>FD placement with intentional stent compression may be effective in the treatment of ICPC AN. When using a small number of coils are used in combination, it is possible to confirm the absence of coil compaction, which may lead to visualization of good results. https://thejns.org/doi/10.3171/CASE25430.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extraskeletal para-articular osteochondroma adjacent to the cervical spine: illustrative case. 毗邻颈椎的骨外关节旁骨软骨瘤:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-15 DOI: 10.3171/CASE25468
Hughes W Benjamin, Lauren E Corliss, Taylor N Murray, Gregory Chamberlin, Deveney Franklin, Mark A Attiah
{"title":"Extraskeletal para-articular osteochondroma adjacent to the cervical spine: illustrative case.","authors":"Hughes W Benjamin, Lauren E Corliss, Taylor N Murray, Gregory Chamberlin, Deveney Franklin, Mark A Attiah","doi":"10.3171/CASE25468","DOIUrl":"10.3171/CASE25468","url":null,"abstract":"<p><strong>Background: </strong>Extraskeletal osteochondromas are well-circumscribed osteocartilaginous lesions arising from soft tissues without bone continuity. Extraskeletal osteochondromas may present in a para-articular location, although few reported cases have occurred near the spine. Clinical diagnosis remains challenging as these tumors can be difficult to distinguish from other ossified soft tissue lesions. Treatment includes management by observation or resection. Here the authors present a rare case of an extraskeletal osteochondroma near the cervical spine.</p><p><strong>Observations: </strong>A 56-year-old male presented with a palpable left paraspinal suboccipital mass that had slowly progressed over 5 years. The patient was asymptomatic and the neurological examination was nonfocal. MRI revealed an approximately 6-cm well-circumscribed heterogeneous mass in the left suboccipital area that lacked direct contact with the spine or calvarium. A hypointense capsule on T2-weighted MRI and multiple hypointense septations on T1- and T2-weighted MRI were identified. The slow rate of tumor growth suggested a benign tumor. CT imaging of the chest, abdomen, and pelvis was obtained to rule out malignancy. Surgical intervention was offered and accepted by the patient. At 2 months postoperatively, imaging demonstrated no recurrence, and the patient was asymptomatic and had improved range of motion.</p><p><strong>Lessons: </strong>Extraskeletal osteochondroma should be considered when diagnosing osteocartilaginous paraspinal masses. https://thejns.org/doi/10.3171/CASE25468.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subdural and epi-arachnoid hemorrhage following spinal epidural block requiring hematoma removal: illustrative case. 脊髓硬膜外阻滞后硬膜下和蛛网膜外出血,需要血肿清除:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-15 DOI: 10.3171/CASE25448
Sang Youp Han, So Un Se, Jae-Won Jang, Yong Eun Cho, Choon-Keun Park
{"title":"Subdural and epi-arachnoid hemorrhage following spinal epidural block requiring hematoma removal: illustrative case.","authors":"Sang Youp Han, So Un Se, Jae-Won Jang, Yong Eun Cho, Choon-Keun Park","doi":"10.3171/CASE25448","DOIUrl":"10.3171/CASE25448","url":null,"abstract":"<p><strong>Background: </strong>Spinal epidural block is widely used for pain control. While complications such as CSF leakage or epidural hematoma are occasionally reported, subdural hematoma (SDH) following an epidural block is rare. To the authors' knowledge, a hematoma involving both the subdural and epi-arachnoid spaces has not been previously reported.</p><p><strong>Observations: </strong>A 49-year-old man with a history of chronic back pain developed severe bilateral leg paresthesia 8 days after a routine lumbar epidural block. MRI revealed an SDH extending from T8 to S3, compressing the dorsal spinal canal. Surgical decompression was performed via hemilaminectomy at L2-3 and L5-S1, followed by durotomy and irrigation with a Nelaton catheter. The patient had full symptomatic relief postoperatively and showed complete hematoma resolution within 3 months.</p><p><strong>Lessons: </strong>Although spinal epidural block is generally considered a safe procedure, rare complications such as SDH can occur. Physicians should maintain a high index of suspicion for such complications in patients presenting without new neurological symptoms after epidural block. When diagnosed with SDH, surgical treatment including laminectomy and irrigation via Nelaton catheter may be necessary to optimize patient outcomes. https://thejns.org/doi/10.3171/CASE25448.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GNAQ mutation in primary spinal melanoma: illustrative case. 原发性脊髓黑色素瘤的GNAQ突变:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-15 DOI: 10.3171/CASE25183
Cristina Hayes Meizoso, Janelle P Renterghem, Constance J Mietus, Brittany Owusu-Adjei, Thomas W Smith, David Cachia, Ali Tasneem, Arno S Sungarian
{"title":"GNAQ mutation in primary spinal melanoma: illustrative case.","authors":"Cristina Hayes Meizoso, Janelle P Renterghem, Constance J Mietus, Brittany Owusu-Adjei, Thomas W Smith, David Cachia, Ali Tasneem, Arno S Sungarian","doi":"10.3171/CASE25183","DOIUrl":"10.3171/CASE25183","url":null,"abstract":"<p><strong>Background: </strong>Primary melanoma in the spine is a rare tumor characterized by lack of primary dermal or uveal lesions. The infrequency of this tumor significantly obfuscates both its diagnosis and treatment.</p><p><strong>Observations: </strong>The authors describe the case of a 74-year-old male who presented with back pain, lower extremity weakness, and numbness. MRI revealed a contrast-enhancing intradural, extramedullary lesion at T11-12 with a hypointense signal on T2-weighted imaging. The patient underwent resection of the lesion. The diagnosis of primary spinal melanoma was confirmed by histopathology, immunohistochemical studies, and lack of primary lesions on dermatological and ophthalmological examination. Next-generation sequencing also revealed a guanine-nucleotide binding protein (GNAQ) mutation.</p><p><strong>Lessons: </strong>The authors present a potential mechanism of primary spinal melanoma tumorigenesis associated with GNAQ. GNAQ mutations lead to abnormal β-catenin activation in neural crest cells, resulting in differentiation into melanoblasts and migration to the spinal cord. Over time, GNAQ mutations can lead to aberrant proliferation of ectopic melanocytes due to downstream activation of the RAS/RAF signaling pathway. Understanding this pathomechanism and its role in primary CNS melanoma may provide a route for potential targeted therapy. https://thejns.org/doi/10.3171/CASE25183.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary malignant melanoma of the pineal region: illustrative case. 松果体区原发性恶性黑色素瘤:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-15 DOI: 10.3171/CASE25242
Jiahong Xu, Jibo Hu, Zhenwei Chen
{"title":"Primary malignant melanoma of the pineal region: illustrative case.","authors":"Jiahong Xu, Jibo Hu, Zhenwei Chen","doi":"10.3171/CASE25242","DOIUrl":"10.3171/CASE25242","url":null,"abstract":"<p><strong>Background: </strong>Primary pineal melanoma is a rare tumor characterized by a high propensity for progression and recurrence. The imaging complexity of the melanoma will pose significant challenges for preoperative diagnosis. Definitive diagnosis necessitates histopathological examination.</p><p><strong>Observations: </strong>The authors present the case of a 49-year-old woman presenting with headache accompanied by nausea and vomiting. Imaging revealed a pineal tumor with subarachnoid hemorrhage. She underwent her first craniotomy at another hospital. Four months after surgery, she was sent to the authors' hospital for a second craniotomy due to recurrent cerebral hemorrhage. The postoperative pathological diagnosis was malignant melanoma in the pineal region.</p><p><strong>Lessons: </strong>In this case, malignant melanoma in the pineal region recurred rapidly and involved the ventricles only 4 months after surgery, suggesting the necessity of close follow-up for rare tumors. In addition, diagnosing this type of tumor on preoperative imaging is challenging, and although pathological diagnosis is the gold standard, the patient in this case required repeat pathological analysis for a definitive diagnosis to be made. https://thejns.org/doi/10.3171/CASE25242.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The gradual expansion of multiple intramedullary metastatic renal cell carcinoma in a patient with von Hippel-Lindau disease with multiple intramedullary hemangioblastomas: illustrative case. 希佩尔-林道病合并多发性髓内血管母细胞瘤患者多发性髓内转移性肾细胞癌逐渐扩大:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-15 DOI: 10.3171/CASE25459
Takao Tsurubuchi, Shunichiro Miki, Hiroyoshi Kino, Hiroyoshi Akutsu, Hitoshi Aiyama, Masahide Matsuda, Noriaki Sakamoto, Eiichi Ishikawa
{"title":"The gradual expansion of multiple intramedullary metastatic renal cell carcinoma in a patient with von Hippel-Lindau disease with multiple intramedullary hemangioblastomas: illustrative case.","authors":"Takao Tsurubuchi, Shunichiro Miki, Hiroyoshi Kino, Hiroyoshi Akutsu, Hitoshi Aiyama, Masahide Matsuda, Noriaki Sakamoto, Eiichi Ishikawa","doi":"10.3171/CASE25459","DOIUrl":"10.3171/CASE25459","url":null,"abstract":"<p><strong>Background: </strong>Patients with von Hippel-Lindau disease (VHLD) often have multiple intramedullary tumors, including hemangioblastoma and rarely intramedullary metastatic renal cell carcinoma (RCC). However, the incidence of intramedullary metastatic clear-cell RCC (CCRCC) comorbid with hemangioblastoma is not clear.</p><p><strong>Observations: </strong>The authors report a rare case of intramedullary metastatic CCRCC comorbid with multiple hemangioblastomas in a patient with VHLD. The preoperative differential diagnosis by MRI was difficult. She underwent three surgical removals. After removal of hemangioblastoma at the first surgery, the juxtaposed tumor grew fast during 3 years. Moreover, 4 years after the second surgery, one of the two adjacent increasing tumors grew faster than another. The pathological diagnoses of both fast-growing tumors were intramedullary metastatic CCRCC, not hemangioblastoma. This patient has no neurological deficits and is now being followed up as an outpatient without any further treatment.</p><p><strong>Lessons: </strong>Although a rare metastatic intramedullary CCRCC is difficult to differentiate from comorbid hemangioblastomas in patients with VHLD, it is important to note that the tumor growth rate differs between hemangioblastoma and metastatic CCRCC, which can be followed using sequential MRI. Care must be taken not to dismiss the timing of the removal of metastatic intramedullary tumors. https://thejns.org/doi/10.3171/CASE25459.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A unique management strategy to bilateral vertebral artery occlusion following cervical trauma: illustrative case. 颈椎外伤后双侧椎动脉闭塞的独特治疗策略:说导性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-15 DOI: 10.3171/CASE25155
Carlos E Calderón-Valero, Esteban Rivera-Rivera, Emil Pastrana-Ramírez, Juan C Vicenty-Padilla
{"title":"A unique management strategy to bilateral vertebral artery occlusion following cervical trauma: illustrative case.","authors":"Carlos E Calderón-Valero, Esteban Rivera-Rivera, Emil Pastrana-Ramírez, Juan C Vicenty-Padilla","doi":"10.3171/CASE25155","DOIUrl":"10.3171/CASE25155","url":null,"abstract":"<p><strong>Background: </strong>Traumatic vertebral artery injury (TVAI) is a serious yet underdiagnosed complication of cervical spine trauma, with an incidence ranging from 0.1% to 3.2%. While its neurological sequelae vary, the risk of vertebrobasilar ischemia can be as high as 33.3%. The authors present a rare case of bilateral vertebral artery occlusion with concomitant basilar artery occlusion following C4-5 anterolisthesis.</p><p><strong>Observations: </strong>The patient initially exhibited no clinical signs of vertebrobasilar ischemia. Diagnosis was achieved through vascular imaging, and successful endovascular thrombectomy with thrombus removal was performed. Unique to this case, manual cervical reduction was carried out in the endovascular suite while maintaining catheter placement in an effort to prevent recurrent dissection or emboli migration.</p><p><strong>Lessons: </strong>Given the transient nature of vertebrobasilar ischemia, repeated imaging and neurological monitoring are crucial for timely intervention. This case highlights the importance of establishing standardized screening and treatment protocols to optimize outcomes and prevent further complications in patients with TVAI. https://thejns.org/doi/10.3171/CASE25155.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nocardia facet sepsis, an indicator of immunocompromise: illustrative case. 诺卡菌关节面败血症,免疫功能低下的指标:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-09-15 DOI: 10.3171/CASE25220
Meera Dhodapkar, Christian Rosenow, Charles-Antoine Mechas, Brett Freedman
{"title":"Nocardia facet sepsis, an indicator of immunocompromise: illustrative case.","authors":"Meera Dhodapkar, Christian Rosenow, Charles-Antoine Mechas, Brett Freedman","doi":"10.3171/CASE25220","DOIUrl":"10.3171/CASE25220","url":null,"abstract":"<p><strong>Background: </strong>Septic facet cysts are a rare phenomenon reported in the literature among immunocompromised hosts and may require operative intervention for appropriate source and symptomatic control.</p><p><strong>Observations: </strong>A 70-year-old male with a past medical history of immunoglobulin A lambda smoldering myeloma degenerative lumbar disease who presented with low back and radicular lower extremity pain was found to have a left L4-5 septic facet cyst with extension to the epidural space. Intraoperative cultures were positive for Nocardia species. Staging workup revealed progression to high-risk-profile multiple myeloma.</p><p><strong>Lessons: </strong>Patients with septic facet cysts may require operative intervention for appropriate source control. Nocardia spine infections and septic facet cysts are rare and require investigation of preexisting risk factors and any potential underlying immunocompromise. https://thejns.org/doi/10.3171/CASE25220.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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