Anay D. Ravelo, Ellan I. Dufour, Makaila Klejeski, Bruce Ziegler, Angie Golombeski, I. Salfer
{"title":"Impacts of feeding milk replacer supplemented with increasing concentrations of choline on feed intake, growth, and scouring incidence for 7 weeks preweaning and 1-week postweaning.","authors":"Anay D. Ravelo, Ellan I. Dufour, Makaila Klejeski, Bruce Ziegler, Angie Golombeski, I. Salfer","doi":"10.3168/jdsc.2024-0557","DOIUrl":"https://doi.org/10.3168/jdsc.2024-0557","url":null,"abstract":": The objective of this study was to evaluate the effect of increasing choline supplementation on the intake of milk replacer (MR) and calf starter (CS), growth performance, and fecal scores of calves over 8 weeks. One hundred calves from commercial herds were transported to the University of Minnesota Southern Research and Outreach Center (SROC) calf facility randomized to one of 4 treatments differing in choline supplementation within MR including: 0 ( C0 ; n = 24), 700 ( C700 ; n = 26), 1400 ( C1400 ; n = 25), and 2100 mg/kg choline ( C2100 ; n = 25). MR contained a basal concentration of 1650 mg/kg MR resulting in total choline concentrations in the MR of 1650 mg/kg for C0 was, 2350 mg/kg for C700 was, 3050 mg/kg for C1400 , and 3750 mg/kg for C2100 . Calves were weaned at 49 d, and the trial ended at 56 d. Body weight (BW) was measured at d 0, 14, 28, 42, 49 and 56. Fecal scores were measured weekly. Feed intake was measured daily and calculated bi-weekly. All feeding, body weight measurements, and fecal scoring were conducted by the research staff at the University of Minnesota SROC. Growth, feed intake, and gain to feed ratio were analyzed using a linear mixed effects model with choline concentration as a fixed effect and source herd and room as random effects. Initial body weight was included as a covariate for average daily gain. Fecal scores were analyzed as a chi-squared test of significance. Feeding 700 mg/kg supplemental choline increased MR intake throughout the preweaning period and increased ADG in both the preweaning and postweaning periods compared with the other treatments. No differences were observed for fecal scores across treatments. Results suggest that calf performance can be improved with MR containing 2350 mg/kg choline, contrasting with current NASEM (2021) requirements of 1000 mg/kg.","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141045966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Q. K. Kolar, S.M. Godden, R.J. Erskine, P. L. Ruegg
{"title":"Confirmed bacteriological diagnosis and cure of non-severe Gram-positive clinical mastitis cases enrolled in a randomized clinical trial based on results of on-farm culture","authors":"Q. K. Kolar, S.M. Godden, R.J. Erskine, P. L. Ruegg","doi":"10.3168/jdsc.2024-0560","DOIUrl":"https://doi.org/10.3168/jdsc.2024-0560","url":null,"abstract":": Our objectives were to describe the confirmed bacteriological diagnosis of mastitis pathogens cultured from cases of non-severe clinical mastitis (CM) identified as Gram-positive (GP) using on-farm culture and to compare differences in bacteriological cure (BC) based on antimicrobial (AM) therapy. Cows that developed non-severe CM in a single quarter were enrolled in a randomized clinical trial based on microbial growth on GP selective agars. Cows were randomly assigned to receive a once-daily intramammary treatment: 3d hetacillin (n = 69), 3d ceftiofur (n = 69), 8d ceftiofur (n = 70) or to a non-treated group (n = 32). Etiologies were confirmed with MALDI-TOF using frozen duplicate milk samples. The crude proportion of BC was determined using milk samples collected at 14, 21 and 28 d after enrollment for cases caused by Streptococci , non-aureus staphylococci (NAS), Strep-like organisms (consisting of Enterococcus and Lactococcus. ; SLO) and Staph. aureus. Multivariable models were used to determine the effect of AM treatment on BC cure at d 21 for a subset of cases that had complete data for all covariates (n = 88). Growth on GP agar resulted in enrollment of 240 cases with confirmed etiologies distributed as Strep. spp (21.7%; n = 52), Lact. spp (19.2%; n = 46), NAS (16.3%; n = 39), Staph aureus (6.3%; n = 16), Entero spp (5.0%; n = 12) and others (10%; n = 24). Thirty-five (14.5%) duplicate milk samples collected from enrolled cows had no significant growth in the lab while 16 (6.7%) were contaminated. Among sampling dates, combined crude BC for cases caused by target pathogens ranged from 68 to 71%. Crude BC ranged from 58 to 73% for the small group of non-treated cases (n = 12) and 69–71% for the combined group of cases that received IMM AM (n = 113). Among all groups and all follow-up dates, crude BC was least for cases caused by Staph. aureus (ranging from 33 to 43%), followed by cases caused by SLO (58–67%), NAS (79–80%) and Strep. spp. (81–91%). The proportion of BC at 21d (LSM ± SE) did not vary between all cases that received AM (0.77 ± 0.06) and cases in the non-treated group (0.73 ± 0.16). The odds of BC at 21d was about 5x greater for cases that occurred in primiparous as compared with multiparous cows and decreased 1.3-fold for each 1 log unit increase in SCC before the case. While this study does not have sufficient power to detect small differences in BC among pathogen groups or treatments, our results demonstrate that CM is caused by a wide diversity of GP bacteria with varying ranges of BC. These results provide justification for inclusion of negative control groups in future studies and confirm that important characteristics such as","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141042439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pamela L. Ruegg, J. L. D. Campos, A. Kates, A. Steinberger, A. Sethi, G. Suen, John Shutske, N. Safdar, Tony Goldberg, P. L. Ruegg8
{"title":"Variation in partial direct costs of dry cow therapy on 37 large dairy herds","authors":"Pamela L. Ruegg, J. L. D. Campos, A. Kates, A. Steinberger, A. Sethi, G. Suen, John Shutske, N. Safdar, Tony Goldberg, P. L. Ruegg8","doi":"10.3168/jdsc.2024-0568","DOIUrl":"https://doi.org/10.3168/jdsc.2024-0568","url":null,"abstract":": The objective of this observational study was to estimate partial direct costs of dry cow antibiotic therapy (DCT) protocols used on 37 large dairy herds in Wisconsin and to estimate the potential monetary savings and reduction in antimicrobial usage (AMU) if selective DCT was used. Partial direct costs of DCT were calculated using costs of intramammary (IMM) antimicrobials and teat seal-ants. Data were retrospectively collected on 37 large dairy farms for a period of one year and included the total number of cows dried-off, types of IMM antimicrobial used, and product","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141029201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. Arshad, M. Cid de la Paz, H.M. White, L.R. Cangiano
{"title":"Characterization of an in vitro model to study CD4+ T cells metabolism in dairy cows","authors":"U. Arshad, M. Cid de la Paz, H.M. White, L.R. Cangiano","doi":"10.3168/jdsc.2024-0565","DOIUrl":"https://doi.org/10.3168/jdsc.2024-0565","url":null,"abstract":",","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141041182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Fukumori, M. Hirose, I. Norimura, T. Nakayama, K. Shimada, H. Mineo, M. Steele, S. Gondaira, H. Higuchi, K. Chisato, S. Oikawa, K. Izumi
{"title":"Effects of lactose content in milk replacer on apparent digestibility, growth, liver mRNA expression, and blood parameters related to metabolism of dairy calves","authors":"R. Fukumori, M. Hirose, I. Norimura, T. Nakayama, K. Shimada, H. Mineo, M. Steele, S. Gondaira, H. Higuchi, K. Chisato, S. Oikawa, K. Izumi","doi":"10.3168/jdsc.2023-0528","DOIUrl":"https://doi.org/10.3168/jdsc.2023-0528","url":null,"abstract":": Even with the same energy supply, differences in energy sources may affect calf growth and metabolism. In this study, we evaluated the effects of feeding 3 different milk replacers (MRs) with different lactose supplies under isoenergetic conditions on calf digestibility, growth, and metabolism-related markers. Fifteen Holstein bull calves were randomly assigned to one of 3 MR-feeding treatments: low-lactose (L:38%), medium-lactose (M:41%), or high-lactose (H:46%). After birth, calves were provided colostrum and treatment MRs were fed from 1 d of age and gradually increased to a maximum feeding rate at 20 d of age (L:1.16 kg/d, M:1.21 kg/d, H:1.26 kg/d DM) without feeding solid feeds during the experimental period. Blood samples were temporarily collected weekly to assess blood concentrations of metabolites and hormones. From 30 to 36 d of age, the calves were euthanized and liver samples were collected to determine growth-related mRNA expression. L calves showed a greater body length than H calves and the highest GHR mRNA expression. Plasma concentrations of total cholesterol, urea nitrogen, total protein, albumin, insulin, and insulin-growth factor-1 were not different, but plasma concentrations of triglycerides were higher in order H, M, and L. These results showed that the difference in lactose content in the MR affected calf metabolism, and the L-MR was suggested to be more likely to enhance growth into the peripheral tissues.","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141027119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabine Mann, T. Westhoff, R. A. Molano, M. E. V. Amburgh, S. Mann1
{"title":"Hemoconcentration differs in neonatal dairy calves: considerations for assessment of transfer of passive immunity","authors":"Sabine Mann, T. Westhoff, R. A. Molano, M. E. V. Amburgh, S. Mann1","doi":"10.3168/jdsc.2024-0570","DOIUrl":"https://doi.org/10.3168/jdsc.2024-0570","url":null,"abstract":": Assessing transfer of passive immunity (TPI) is a critical management strategy to evaluate colostrum management and feeding; however, variability in hemoconcentration or serum or plasma volume in calves might influence TPI assessment. The objectives of this study were to 1) describe the variability in hemoconcentration as well as TPI in Holstein calves in New York State and 2) describe the effect of adjusting total protein (TP) for the degree of hemoconcentration by applying a sample average proportion of plasma in blood (PP) on TPI assessment. Records of TP and PP from 703 1 to 9 d of age Holstein calves from 19 commercial dairy farms were analyzed. The PP was determined by centrifugation of microhematocrit tubes and serum, and plasma TP was determined by digital refractometry. Transfer of passive immunity was categorized using unadjusted TP (uTP) as excellent = ≥ 6","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141038391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A note from the Editor in Chief of JDS Communications: Connecting via coffee and ice cream","authors":"JessicaA.A. McArt Editor in Chief","doi":"10.3168/jdsc.2024-0578","DOIUrl":"https://doi.org/10.3168/jdsc.2024-0578","url":null,"abstract":"","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266691022400053X/pdfft?md5=9b85d213d581ec34112cf8749b37e4ab&pid=1-s2.0-S266691022400053X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140543410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Spaans, J. R. Roche, C. Burke, C. Phyn, S. McDougall, C. Reed, B. Kuhn-Sherlock, A. Hickey, A. Heiser, M. Crookenden
{"title":"Specificity of two peripartum blood markers for early lactation acute uterine inflammation in pasture-fed, seasonal-calving dairy cows.","authors":"O. Spaans, J. R. Roche, C. Burke, C. Phyn, S. McDougall, C. Reed, B. Kuhn-Sherlock, A. Hickey, A. Heiser, M. Crookenden","doi":"10.3168/jdsc.2023-0509","DOIUrl":"https://doi.org/10.3168/jdsc.2023-0509","url":null,"abstract":"","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140765025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Murayama, N. Kobayashi, N. Nishizawa, M. Oba, T. Sugino
{"title":"Evaluation of serum concentrations of total protein and gamma-globulin as an indicator of serum immunoglobulin G concentration in dairy calves","authors":"K. Murayama, N. Kobayashi, N. Nishizawa, M. Oba, T. Sugino","doi":"10.3168/jdsc.2023-0469","DOIUrl":"https://doi.org/10.3168/jdsc.2023-0469","url":null,"abstract":"","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140793112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}