JDS communicationsPub Date : 2026-03-01Epub Date: 2025-12-01DOI: 10.3168/jdsc.2025-0898
R.B. Stephansen , B.G. Poulsen , J. Lassen , J. Jensen
{"title":"Genetic associations between feed efficiency traits and breeding goal traits in Nordic Holsteins","authors":"R.B. Stephansen , B.G. Poulsen , J. Lassen , J. Jensen","doi":"10.3168/jdsc.2025-0898","DOIUrl":"10.3168/jdsc.2025-0898","url":null,"abstract":"<div><div>Genetic selection is a viable tool for improving feed efficiency due to its cumulative nature. However, it has not been investigated how selection for feed efficiency affects other breeding goal traits. This work investigated associations between the feed efficiency–related traits BW (representing energy requirement for body maintenance), genetic residual feed intake (gRFI; representing deviations from expected feed intake calculated from milk yield, maintenance, and changes in BW), genetic Feed Saved (gFS; representing deviations from expected feed intake calculated from milk yield, and changes in BW), and all breeding goal traits in the Nordic Total Merit (NTM) index. Phenotypic data were collected from 5,104 cows across 8 commercial herds using the Cattle Feed InTake system, and GEBVs for feed efficiency were estimated using the single-step genomic BLUP methodology. Genetic correlations were approximated using Pearson correlation between GEBVs for different traits. The genetic correlations were weakly negative between BW and NTM (−0.15 to −0.18) or longevity (−0.13 to −0.15), and it was not associated with the yield index. The genetic correlations were generally moderate between BW and conformation traits such as stature and chest width but not with dairy form. The genetic correlations for gRFI in different lactation stages were weakly to moderately correlated with the yield index (−0.23 to 0.21) and weakly correlated with functional traits (−0.10 to 0.10; e.g., mastitis, female fertility). Furthermore, gRFI in early lactation of multiparous cows was weakly and unfavorably correlated with longevity (−0.14). The genetic correlations between gFS and yield, functional traits, and longevity were low (−0.13 to 0.16). However, the moderate negative genetic correlation between gFS and frame (−0.37 to −0.28) indicated that more efficient cows have a smaller frame. In conclusion, our results indicated that feed efficiency traits such as gRFI and gFS can be integrated into breeding goals with limited adverse effects on yield, functional traits, and longevity. Selection for lower BW may enhance longevity without compromising yield.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 198-203"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2025-10-18DOI: 10.3168/jdsc.2025-0782
Andreas R. Böker , Roswitha Merle , Phuong Do Duc , Antonia Hentzsch , Annegret Stock , Frederike Reichmann , Alexander Bartel , Svenja Woudstra , Martina Hoedemaker
{"title":"Drying-off practices and cell count–based new infection and cure risk over the dry period on 765 German dairy farms","authors":"Andreas R. Böker , Roswitha Merle , Phuong Do Duc , Antonia Hentzsch , Annegret Stock , Frederike Reichmann , Alexander Bartel , Svenja Woudstra , Martina Hoedemaker","doi":"10.3168/jdsc.2025-0782","DOIUrl":"10.3168/jdsc.2025-0782","url":null,"abstract":"<div><div>This observational study with voluntary participation investigated drying-off practices and dry period-related udder health key performance indicators in 3 important dairy production regions in Germany (the north [NR], east [ER], and south [SR]). Data from DHI testing and information about drying-off practices were collected during a single herd visit between 2016 and 2019 from 253, 252, and 260 farms in NR, ER, and SR, respectively. Abrupt cessation of lactation was most common in NR and ER, but only practiced on about half of the farms in SR (NR: 79%, ER: 75%, SR: 56%). Blanket dry cow therapy (BDCT, the use of antibiotic agents for all cows) dominated in NR and ER (63% and 65%, respectively), whereas in SR, primarily selective dry cow therapy (SDCT, targeted use of antibiotic agents at drying-off for individual cows according to farm-specific criteria; 56%) or even no use of antibiotic dry cow therapy (20%) were adopted. The use of teat sealants (TSL) with or without the use of antibiotics was most common in ER (66%), followed by farms in NR (54%), and least common in SR (30%). The median new infection risk (using a SCC threshold of 100,000 cells/mL of milk) during the dry period (NIRD; cows with SCC ≤100,000 before dry period and SCC >100,000 at first test-day post dry period) in NR, ER, and SR was 24% (interquartile range: 13%–35%), 25% (18%–35%), and 24% (8%–37%), and the cure risk during the dry period (CRD; cows with SCC >100,000 before dry period and SCC ≤100,000 at first test-day post dry period) in NR, ER, and SR was 63% (51%–72%), 57% (47%–65%), and 60% (42%–75%), respectively. The NIRD and CRD varied greatly between farms, indicating improvement potential on many dairy farms.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 227-232"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2026-01-16DOI: 10.3168/jdsc.2025-0902
Usman Arshad, Martin Huser, Mario A. Barrientos-Blanco, Md Zakirul Islam, Xiaoqi Ma, Rong Peng, Kai Wang, Mutian Niu
{"title":"Dietary starch levels modulate production performance and whole-body nutrient metabolism in dairy cows","authors":"Usman Arshad, Martin Huser, Mario A. Barrientos-Blanco, Md Zakirul Islam, Xiaoqi Ma, Rong Peng, Kai Wang, Mutian Niu","doi":"10.3168/jdsc.2025-0902","DOIUrl":"10.3168/jdsc.2025-0902","url":null,"abstract":"<div><div>The objective of this study was to evaluate the effects of increasing dietary starch concentrations on production performance and whole-body nutrient metabolism in lactating dairy cows. Twelve multiparous Holstein cows at mean (±SD) 89 ± 13 DIM were assigned to a replicated 3 × 3 Latin square design comprising three 21-d periods. Each period consisted of 14-d dietary adaptation followed by 7 d of data and sample collection. Treatments consisted of low-starch (LS; 9.66% of DM), medium-starch (MS; 20.6% of DM), and high-starch (HS; 29.1% of DM) diets. Crude protein concentrations were 15.9%, 14.7%, and 14.7%, and NDF concentrations were 47.9%, 38.3%, and 36.6% for the LS, MS, and HS diets, respectively. Dry matter intake and milk yield and composition were measured throughout the sampling week. Gas exchange including CH<sub>4</sub>, O<sub>2</sub>, and CO<sub>2</sub> were measured using a head chamber (GreenFeed system) on the last day of the sampling period for the calculation of respiratory quotient, net carbohydrate oxidation (COX<sub>net</sub>), net fat oxidation (FOX<sub>net</sub>), and metabolic heat production (mHP). Least squares means and SEM are presented in the sequence of LS, MS, and HS. Increasing dietary starch concentration linearly increased net energy intake (38.9 vs. 40.3 vs. 40.7 ± 0.87 Mcal/d) and milk yield (33.5 vs. 36.6 vs. 38.9 ± 1.24 kg/d), and tended to linearly increase ECM yield (39.1 vs. 43.5 vs. 43.1 ± 1.50 kg/d), without a concurrent increase in DMI or BW loss, resulting a tendency for improved feed efficiency (ECM/DMI; 1.62 vs. 1.77 vs. 1.78 ± 0.06 kg/kg) in dairy cows. Yield of milk true protein increased linearly (1.17 vs. 1.37 vs. 1.34 ± 0.06 kg/d), whereas MUN concentrations decreased linearly (18.1 vs. 12.9 vs. 10.4 ± 0.56 mg/dL) with increasing dietary starch. Respiratory quotient tended to respond quadratically, remaining similar in LS and MS but higher in HS-fed cows (0.90 vs. 0.90 vs. 0.94 ± 0.01), indicating a shift in substrate oxidation toward greater carbohydrate utilization. Correspondingly, increasing dietary starch concentration linearly increased COX<sub>net</sub>, both in absolute (5,432 vs. 5,848 vs. 7,276 ± 366 g/d) and metabolic BW (mBW) adjusted terms (39.0 vs. 41.6 vs. 52.0 ± 2.6 g/kg mBW). In contrast, FOX<sub>net</sub> responded quadratically, peaking in MS both in absolute (742 vs. 906 vs. 450 ± 150 g/d) and mBW-adjusted terms (5.28 vs. 6.42 vs. 3.29 ± 1.07 g/kg mBW). Consistently, mHP increased linearly with starch concentration, both in absolute (34.8 vs. 37.4 vs. 38.1 ± 0.73 Mcal/d) and mBW-adjusted terms (0.25 vs. 0.26 vs. 0.27 ± 0.01 Mcal/kg mBW), indicating greater energy expenditure. Overall, these findings indicate that increasing dietary starch shifted whole-body substrate oxidation toward carbohydrates and improved energy utilization and feed efficiency in mid-lactation dairy cows.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 168-173"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2025-12-13DOI: 10.3168/jdsc.2025-0867
Tainara C. Michelotti , Alyssa Imbert , Arash Veshkini , Guillaume Durand , Harald M. Hammon , Muriel Bonnet
{"title":"Expression of free fatty acid receptors in the liver of periparturient dairy cows supplemented with essential fatty acids and conjugated linoleic acid","authors":"Tainara C. Michelotti , Alyssa Imbert , Arash Veshkini , Guillaume Durand , Harald M. Hammon , Muriel Bonnet","doi":"10.3168/jdsc.2025-0867","DOIUrl":"10.3168/jdsc.2025-0867","url":null,"abstract":"<div><div>Free fatty acid receptors (FFAR) are molecular sensors involved in the regulation of energy metabolism. Free fatty acid receptors are expressed in the bovine liver, although their biological functions are not fully understood. Our objectives were to study the expression of hepatic FFAR in periparturient dairy cows supplemented or not with a mixture of essential fatty acids (EFA) and CLA, and to investigate potential associations between FFAR and metabolic adaptation during the transition period. Multiparous Holstein cows received abomasal infusions of either coconut oil (control; n = 8) or a mixture of EFA and CLA (EFACLA; n = 8) from −9 to 9 wk relative to parturition. Liver samples were collected at −3, 0, 4, and 9 wk relative to parturition. We quantified the liver expression of FFAR (<em>FFAR1</em>–<em>4</em> and <em>GPR84</em>) and peroxisome proliferator-activated receptor delta (<em>PPARD</em>) by real-time quantitative PCR. Repeated-measurement correlations and multilevel multiple factor analysis (MFA) were used to investigate the links between FFAR and other metabolic parameters (i.e., energy balance, blood metabolic indicators, liver proteomics, and liver gene expression). All targeted FFAR were expressed in the liver, except for <em>FFAR4</em>. We found no effects of EFACLA or interactions with time for the expressed FFAR. <em>FFAR1</em>, <em>FFAR2</em>, and <em>GPR84</em> expression decreased from −3 to 9 wk relative to parturition, whereas <em>FFAR3</em> remained constant from −3 to 4 wk, then decreased at 9 wk postpartum. We observed strong correlations between FFAR, and moderate correlations between FFAR and <em>PPARD.</em> Multivariate (MFA) and univariate (correlation) analyses revealed weak links between FFAR liver expression and other metabolic parameters (e.g., <em>IGFBP3</em> liver expression and plasma IGFBP-2). Downregulation of FFAR in the liver from pre- to postpartum may prevent receptors hyperactivation during periods of high free fatty acid concentrations. Physiological relevance and individual contributions of FFAR to the hepatic metabolism require further investigation.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 278-283"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2025-12-04DOI: 10.3168/jdsc.2025-0803
Zs. Bohák , H. Kiszlinger Nagyné , F. Hoffmann , L. Kern , L. Kovács
{"title":"Heart rate and heart rate variability of dairy cows with or without local anesthesia","authors":"Zs. Bohák , H. Kiszlinger Nagyné , F. Hoffmann , L. Kern , L. Kovács","doi":"10.3168/jdsc.2025-0803","DOIUrl":"10.3168/jdsc.2025-0803","url":null,"abstract":"<div><div>Heart rate variability analysis provides valuable insights into autonomic nervous system function but remains minimally explored in veterinary anesthesiology, particularly regarding its relationship with low-dose caudal epidural anesthesia in cattle. This study employed a crossover design to determine whether epidural lidocaine administration (4 mL of 2% solution) affects cardiac autonomic regulation compared with physiological saline in 8 healthy Holstein-Friesian dairy cows. Interbeat intervals were measured at baseline and for 240 min following epidural injection and cardiac autonomic activity-related parameters of heart rate variability (heart rate, root mean square of successive differences, high-frequency component, and ratio of low-frequency and high-frequency components) were calculated. Area under the curve for the first 240 min after the treatment and time to return to baseline were used to evaluate overall treatment effects on cardiac autonomic activity. Results revealed no differences in the area under the curve values for any parameters of heart rate variability between lidocaine and saline epidural interventions throughout the observation period, with comparable recovery times to baseline values between treatments. These findings suggest that sacrococcygeal epidural anesthesia did not detectably affect cardiac autonomic regulation in dairy cows under the conditions of this study.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 262-267"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2025-12-04DOI: 10.3168/jdsc.2025-0876
Martin Zinicola , Reinaldo F. Cooke , Francisco Larghi
{"title":"Administering the maternal bovine appeasing substance improves fertility in lactating dairy cows","authors":"Martin Zinicola , Reinaldo F. Cooke , Francisco Larghi","doi":"10.3168/jdsc.2025-0876","DOIUrl":"10.3168/jdsc.2025-0876","url":null,"abstract":"<div><div>This experiment evaluated the effects of administering the maternal bovine appeasing substance (mBAS) at the time of artificial insemination (AI) on pregnancy per AI (P/AI) of Holstein cows under commercial dairy conditions. A total of 375 lactating Holstein dairy cows (178 primiparous and 197 multiparous cows) from 2 commercial dairy farms were enrolled. All cows were assigned to an ovulation synchronization + AI protocol when they reached 65 DIM. The protocol included 2 mg of estradiol benzoate + intravaginal progesterone-releasing device (DIB) on d −10, followed by 25 mg of dinoprost tromethamine on d −3, followed by 25 mg of dinoprost tromethamine + 1 mg of estradiol cypionate + 400 IU of equine chorionic gonadotropin + DIB removal and tail paint on d −2. On d 0 (24 h after tail paint application), cows with paint removed were classified as in estrus and inseminated. Cows with intact tail paint were considered not to be in estrus, administered 100 µg of GnRH, and inseminated 8 h later. At the time of AI, cows within farm and parity were randomly assigned to receive mBAS (Ferappease, FERA Diagnostics and Biologicals, College Station, TX; n = 197) or no treatment (CON, n = 178). The mBAS (10 mL) was applied topically to the nuchal skin area (5 mL) and above the muzzle (5 mL). Pregnancy status to AI was verified by detecting a viable embryo with transrectal ultrasonography 32 d after AI. Cows assigned to mBAS or CON had similar DIM at the time of AI, milk yield, and incidence of estrus during the synchronization protocol. Administering mBAS increased P/AI by 12.5 percentage points compared with CON cows (60.2% vs. 47.7%). Based on treatment differences in P/AI and an economic value of $200/pregnancy, mBAS administration yielded a return-on-investment of 833%. This calculation assumed mBAS cost of $3.00/cow, a herd of 1,000 cows in which mBAS yielded 125 more pregnancies, resulting in an economic benefit of $25,000 ($25,000/$3,000 = 8.33). The results of this experiment are novel and provide evidence that mBAS is effective in enhancing the reproductive performance of lactating dairy cows when applied during critical stress-sensitive periods such as AI.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 268-272"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2025-10-18DOI: 10.3168/jdsc.2025-0887
Kate Sorensen, Niharika Mishra, Taylor S. Oberg
{"title":"Sensitivity of Paucilactobacillus wasatchensis strains to nisin","authors":"Kate Sorensen, Niharika Mishra, Taylor S. Oberg","doi":"10.3168/jdsc.2025-0887","DOIUrl":"10.3168/jdsc.2025-0887","url":null,"abstract":"<div><div><em>Paucilactobacillus wasatchensis</em> is a nonstarter lactic acid bacterium that has been isolated throughout the United States and is associated with late blowing gas defect (LBD), a continuing problem in the cheese industry, which results in downgraded product and economic loss. Although the route of <em>Pa. wasatchensis</em> contamination in milk destined for cheesemaking remains inconclusive, the addition of nisin or the application of nisin-producing starter cultures in Cheddar production may mitigate LBD by inhibiting <em>Pa. wasatchensis.</em> Nisin sensitivity has not yet been evaluated for <em>Pa. wasatchensis</em> strains. The goal of the current study was to evaluate 8 strains of <em>Pa. wasatchensis</em> for nisin sensitivity using the agar well diffusion method. Nisin inhibition was evaluated across a range from 5 to 100 IU/mL. To compare strain sensitivity, the lowest nisin concentration that displayed inhibition for all strains was selected (30 IU/mL), and the corresponding inhibition zones were statistically analyzed by ANOVA with a Tukey–Kramer post hoc test. The MIC for each strain were also estimated. Each <em>Pa. wasatchensis</em> strain showed inhibition within the tested range of nisin concentration. Results from the Tukey–Kramer post hoc test showed some strain differences in nisin sensitivity, but these were not correlated with region of isolation. All strains showed inhibition at 30 IU/mL nisin, which indicates that <em>Pa. wasatchensis</em> is highly sensitive to nisin. This supports addition of nisin, or the application of nisin protective cultures, as a potential effective strategy in mitigating LBD caused by <em>Pa. wasatchensis</em>.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 122-127"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2026-01-16DOI: 10.3168/jdsc.2025-0846
J.L. Bermeo , L.C. Solórzano , A. Rico , N. Silva-del-Río
{"title":"Evaluation of a creatinine-based equation to predict urine volume in nonpregnant, nonlactating Holstein cows","authors":"J.L. Bermeo , L.C. Solórzano , A. Rico , N. Silva-del-Río","doi":"10.3168/jdsc.2025-0846","DOIUrl":"10.3168/jdsc.2025-0846","url":null,"abstract":"<div><div>Accurate estimation of urine output is essential for assessing nutrient utilization, particularly for nutrients predominantly excreted through urine, such as minerals and protein-derived metabolites. An equation utilizing creatinine concentration and BW has been previously developed to estimate urinary volume (EUV) in lactating Holstein dairy cows, defined as EUV = [29 × BW (kg)]/[urinary creatinine (mg/L)]. Our objective was to evaluate whether this equation introduces bias when used for estimating urinary output in nonpregnant, nonlactating Holstein cows and to identify factors influencing its accuracy. For our study, we used 72 paired observations that included observed urinary volume (OUV) and urinary creatinine concentration. These observations were obtained from a prior research study that assessed the relative availability of various magnesium (Mg) sources using a duplicated 6 × 6 Latin square design, with cows (n = 12) grouped into squares based on lower (square 1) or higher (square 2) BW across 6 periods. Enrolled cows were of second parity (n = 8) and third or greater parity (n = 4), with BW ranging from 590 to 831 kg. To determine the agreement between EUV and OUV, we constructed 2 mixed-effects models. The first model evaluated slope bias (testing if the slope was significantly different from 1), whereas the second assessed mean bias (testing if the intercept was significantly different from 0) between EUV and mean-centered OUV. In our dataset, creatinine excretion per kilogram of BW ranged from 15.0 to 35.6 mg/kg BW with an average of 27.6 mg/kg BW. When assessing the agreement between OUV and EUV, we observed both slope and mean biases when applying the creatinine-based equation. Furthermore, there was a bias estimate across BW quartiles. Overall, 76.4% of observations fell within ±10% deviation range between EUV and OUV. These findings suggest that further research is needed to identify factors that can refine the creatinine and BW-based predictive equation specifically for nonpregnant, nonlactating Holstein dairy cows.</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 174-178"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JDS communicationsPub Date : 2026-03-01Epub Date: 2025-12-13DOI: 10.3168/jdsc.2025-0831
José G. Cortes-Hernández , Guillermo Martinez-Boggio , Francisco Peñagaricano , Hugo H. Montaldo , Felipe J. Ruiz-López , Adriana García-Ruiz
{"title":"Predicting productive, health, and reproductive traits in Mexican Holstein cattle using single nucleotide polymorphisms, haplotypes, and runs of homozygosity","authors":"José G. Cortes-Hernández , Guillermo Martinez-Boggio , Francisco Peñagaricano , Hugo H. Montaldo , Felipe J. Ruiz-López , Adriana García-Ruiz","doi":"10.3168/jdsc.2025-0831","DOIUrl":"10.3168/jdsc.2025-0831","url":null,"abstract":"<div><div>The aim of this study was to evaluate the use of 3 different genomic relationship matrices built from SNPs, haplotypes (HAP), and runs of homozygosity (ROH), on phenotype predictive ability and estimated genetic variance of milk yield, SCS, and days open in Mexican Holstein cattle. The analyses included the use of the genomic relationship matrices as kernel-based models fitting either one or multiple sources of information. The SNPs and HAP matrices were built as linear kernels, and the ROH matrix as a Gaussian kernel. Also, we used as a reference the performance of the single-step GBLUP. Predictive ability was evaluated in 10-fold cross-validation. The highest predictive correlation was obtained using SNPs (0.63 for SCS, 0.57 for milk yield, and 0.20 for days open). The use of multigenomic relationships, including HAP and ROH, did not outperform the use of only SNPs in predictive ability, but the highest genetic variance was estimated using ROH (0.39 for milk yield, 0.26 for SCS, and 0.22 for days open).</div></div>","PeriodicalId":94061,"journal":{"name":"JDS communications","volume":"7 2","pages":"Pages 216-221"},"PeriodicalIF":2.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}