Ginekologia polska最新文献_第6页

Clinical application of synthetic osmotic cervical dilator in labor pre-induction: departmental protocol and literature review. 人工合成渗透性宫颈扩张器在引产前的临床应用：部门规程和文献综述。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-11-08 DOI: 10.5603/gpl.100984

Maisa Manasar-Dyrbus, Katarzyna Wilk, Maja Zieba-Domalik, Jakub Staniczek, Rafal Stojko

引用次数: 0

Evaluation of the utility of the sFlt-1/PlGF ratio in pregnancy complicated by pre-eclampsia - single-center study. Preliminary analysis.

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-01-29 DOI: 10.5603/gpl.101484

Justyna A Kuciel, Jagoda N Sarad, Natalia M Mroczek, Andrzej Jaworowski, Magdalena L Kolak, Hubert K Huras

{"title":"Evaluation of the utility of the sFlt-1/PlGF ratio in pregnancy complicated by pre-eclampsia - single-center study. Preliminary analysis.","authors":"Justyna A Kuciel, Jagoda N Sarad, Natalia M Mroczek, Andrzej Jaworowski, Magdalena L Kolak, Hubert K Huras","doi":"10.5603/gpl.101484","DOIUrl":"10.5603/gpl.101484","url":null,"abstract":"Objectives: To evaluate relationship between sFlt-1/PlGF ratio, clinical characteristics and outcomes of pre-eclampsia.Material and methods: Retrospective analysis of 29 pregnant women with pre-eclampsia who had measured sFlt-1/PlGF ratio was conducted using electronic medical records from Obstetrics and Perinatology ward of University Hospital in Cracow.Results: Women median age: 33.5 years, number of pregnancies: one 52%, two 15%, three 18%,more than three 15%, number of deliveries: one 59.3%, two 37%, three 3.7%, median body mass index during hospitalization: 29.4 kg/m². Chronic diseases apart from hypertension: 67% of women (diabetes 37%, hypothyroidism 26%, obesity 11%). Median newborns birth weight: 1640 g, median Apgar score at 5 minutes: 8, median umbilical cord blood pH: 7.32. Fetal growth restriction: 28.6% of cases. All deliveries were by c-section. Median gestational age at delivery: 32 weeks. sFlt-1/PlGF ratio was inversely correlated with gestational age at delivery (r = -0.42, p = 0.02). The median sFlt-1/PlGF ratio was higher in women with severe pre-eclampsia (n = 15) than in those with mild pre-eclampsia (n = 14) (211 vs. 57, p < 0.001). sFlt-1/PlGF ratio of > 85 had a sensitivity of 80% and a specificity of 71% for predicting severe pre-eclampsia.Conclusions: sFlt-1/PlGF ratio is useful in assessing the severity and prognosis of pre-eclampsia. sFlt-1/PlGF ratio should not be used as a sole criterion for making clinical decisions, but as an adjunct to other clinical and laboratory parameters.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"148-152"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Folic acid versus folinic acid during methotrexate treatment for low-risk gestational trophoblastic neoplasia. 在甲氨蝶呤治疗低风险妊娠滋养细胞肿瘤期间，叶酸与亚叶酸的比较。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-02-04 DOI: 10.5603/gpl.101142

Mehmet Şükrü Budak, Süleyman Cemil Oğlak, Sedat Akgöl, Behzat Can, Kevser Arkan, Ali Deniz Erkmen, Mesut Ali Halisçelik, Adnan Budak, Şeyhmus Tunç, Gökhan Bolluk, Emine Zeynep Yılmaz, Özgür Akbayır

{"title":"Folic acid versus folinic acid during methotrexate treatment for low-risk gestational trophoblastic neoplasia.","authors":"Mehmet Şükrü Budak, Süleyman Cemil Oğlak, Sedat Akgöl, Behzat Can, Kevser Arkan, Ali Deniz Erkmen, Mesut Ali Halisçelik, Adnan Budak, Şeyhmus Tunç, Gökhan Bolluk, Emine Zeynep Yılmaz, Özgür Akbayır","doi":"10.5603/gpl.101142","DOIUrl":"10.5603/gpl.101142","url":null,"abstract":"Objectives: To evaluate and compare the treatment results of folinic acid (FA) and folic acid (F) added to the chemotherapy protocol to reduce the toxicity due to methotrexate (MTX) in the treatment of low-risk gestational trophoblastic neoplasia (GTN) patients.Material and methods: Patients treated for low-risk GTN at two reference centers between January 2000 and March 2023 were included in this retrospective study. Patients were divided into two groups, MTX/FA and MTX/F. Both groups received 50 mg/day MTX on days 1, 3, 5, 7 of treatment. On days 2, 4, 6, 8 of treatment 0.1 mg/kg folinic acid was administered to the MTX/FA group, and 20 mg/day folic acid was administered to the MTX/F group to reduce MTX toxicity. The groups were compared according to treatment success, resistance, and the development of toxicity.Results: Among 102 low-risk GTN patients included in the study, 64.7% (n = 66) were in the MTX/FA, while the remaining 35.3% (n = 36) were in the MTX/F group. There was no significant difference between MTX/FA and MTX/F groups regarding treatment success, resistance, and toxicity rates (84.8%, 13.6%, 1.6% vs 83.3%, 13.8%, 2.7%), respectively.Conclusions: Replacement of folinic acid with folic acid in low-risk GTN patients to reduce the toxicity that may develop associated with MTX treatment resulted in similar treatment success rates. Still, no significant change was observed regarding toxicity and resistance. There is a need for comprehensive prospective studies to further elucidate this relationship.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"200-205"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of body mass index and gestational weight gain on cesarean delivery rates: a comparative study of dinoprostone-induced vs spontaneous labor. 体重指数和妊娠体重增加对剖宫产率的影响：地诺前列酮诱导分娩与自然分娩的比较研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.5603/gpl.100230

Andrzej Jaworowski, Agnieszka Micek, Magdalena Kolak, Katarzyna Skibinska-Frankowska, Julia Jurga, Kuba Ptaszkiewicz, Hubert Huras

{"title":"Impact of body mass index and gestational weight gain on cesarean delivery rates: a comparative study of dinoprostone-induced vs spontaneous labor.","authors":"Andrzej Jaworowski, Agnieszka Micek, Magdalena Kolak, Katarzyna Skibinska-Frankowska, Julia Jurga, Kuba Ptaszkiewicz, Hubert Huras","doi":"10.5603/gpl.100230","DOIUrl":"10.5603/gpl.100230","url":null,"abstract":"Objectives: This study investigates the relationship between pre-pregnancy body mass index (BMI), BMI before labor, and weight gain during pregnancy with the incidence of cesarean delivery (CD) in dinoprostone-induced labor versus spontaneous labor.Material and methods: This retrospective analysis was carried out at the Jagiellonian University Hospital's Obstetrics and Perinatology Department, encompassing term singleton pregnancies from May 2019 to February 2021. BMI was categorized following WHO guidelines. Gestational weight gain was assessed against the Institute of Medicine's 2009 recommendations.Results: Of the 366 cases reviewed, 183 were in the dinoprostone-induced labor group, and 183 were in the spontaneous labor group. The study identified a significant association between higher pre-pregnancy BMI and increased weight gain during pregnancy with elevated CD rates, especially in dinoprostone-induced labor compared to spontaneous labor. Specifically, the dinoprostone-induced labor group showed a 33.9% CD rate compared to 16.9% in the spontaneous labor group. Logistic regression analysis further established that for each 1 kg/m² increase in pre-pregnancy BMI, the odds of undergoing a CD increased by 10%.Conclusions: Elevated pre-pregnancy BMI and excessive gestational weight gain significantly heighten the risk of cesarean delivery, particularly in induced labor. The findings underline the need for individualized labor management strategies for women with higher BMI to optimize maternal and neonatal outcomes.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cystocele and rectocele repair with native tissue layers: definition of the technique. 用天然组织层修复囊突和直肠突：技术的定义。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.5603/gpl.100446

Ozan Dogan, Cagri Gulumser, Gokce Gokkaya, Murat Yassa

{"title":"Cystocele and rectocele repair with native tissue layers: definition of the technique.","authors":"Ozan Dogan, Cagri Gulumser, Gokce Gokkaya, Murat Yassa","doi":"10.5603/gpl.100446","DOIUrl":"10.5603/gpl.100446","url":null,"abstract":"Objectives: To investigate the outcomes of central cystocele and rectocele repair using natural tissue layers. To describe a novel technique (Dogan technique).Material and methods: This is a retrospective cohort study. Between January 2021 and January 2023, patients who had central cystocele and rectocele higher than stage1 were included in the study. The Pelvic Organ Prolapse Quantification (POP-Q) score was used to determine the degree of the prolapsus. All cystocele and rectocele repair surgeries were performed by the same physician. The patients' voiding habits were assessed using ICIQ-SF and OAB-V8. Sexual function results were assessed with FSFI questionnaire before and after the operation. Transperineal ultrasonography was performed to examine mobility of the anterior and posterior compartments.Results: Total of 36 patients were diagnosed with grade 2 and above central cystocele (19, 52%) and rectocele (n = 17, 48%). After the operation the anatomical cure of anterior and posterior compartments was achieved for all patients in the two-years follow-up. According to voiding habits before the surgery, there were symptoms of stress urinary incontinence (SUI),urge urinary incontinence (URGE), both SUI and URGE, and no incontinence at the patients; 7 (36.8%), 14 (73.7%), 5 (26.3%), 3 (15.7%) respectively. Of those URGE patients (n = 5/14, 35.7%) incontinence symptoms were mixed-type. After the cystocele operation, significant improvement was seen in their voiding problems according to the ICIQ-SF and OAB-V8 questionnaires (p < 0.05). As well as significant improvement was found in sexual function according to the FSFI questionnaire (p < 0.05).Conclusions: We showed that strengthening the anterior and/or posterior compartments with native tissue improves urge and voiding dysfunctions via a novel technique (Dogan technique) without removing the vagina tissue.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"13-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modified laparoscopic sacrocolpopexy for advanced posterior vaginal wall prolapse: a 3-year prospective study. 改良腹腔镜骶骨结扎术治疗晚期阴道后壁脱垂：一项为期三年的前瞻性研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-10-29 DOI: 10.5603/gpl.100017

Yifan Yin, Yufang Xia, Shujun Ji, Enhui Guo, Chen Chen, Yanhui Lou

{"title":"Modified laparoscopic sacrocolpopexy for advanced posterior vaginal wall prolapse: a 3-year prospective study.","authors":"Yifan Yin, Yufang Xia, Shujun Ji, Enhui Guo, Chen Chen, Yanhui Lou","doi":"10.5603/gpl.100017","DOIUrl":"10.5603/gpl.100017","url":null,"abstract":"Objectives: To evaluate and validate the safety and efficacy of modified laparoscopic sacrocolpopexy for advanced posterior vaginal wall prolapse at up to 3 years of follow-up.Material and methods: As a prospective observational study, we collected 56 cases with advanced posterior vaginal wall prolapse and performed modified laparoscopic sacrocolpopexy (MLSC) with self-cut mesh. The main improvement is the cutting and fixing of the mesh. Patients were followed up at 6, 12, 24 and 36 months. The main indicators of follow-up were postoperative anatomic success rate and Pelvic organ prolapse quantitation (POP-Q) score, and secondary indicators were related to quality-of-life scales and postoperative complication rates.Results: All patients completed the operation through minimally invasive surgery, and there were no vital organs and blood vessel damage during the operation. The mean age was (58.32 ± 7.63) years. There was no recurrence of stage I or lower during the follow-up maximum of 36 months (median 24 months), and the anatomic success rate was 100%. The quality-of-life scores improved significantly (p < 0.001) and the quality of sexual life was not affected (p = 0.5). There was 1 case of continuous vaginal mesh exposure at 12 months (2.86%) and 1 case of severe infection with poor healing of vaginal stump within 6 months (1.79%). No one had urinary incontinence (UI) requiring reoperation.Conclusions: In patients with advanced posterior vaginal wall prolapse, MLSC can provide good and durable pelvic floor anatomical recovery and functional outcomes with no specific complications.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"87-95"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traditional vs novel out-of-office method for collecting cytology and HPV DNA - a comparative study. 传统与新型诊室外细胞学和人乳头瘤病毒 DNA 采集方法的比较研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.5603/gpl.100294

Marcin Januszewski, Laura M Ziuzia-Januszewska, Andrzej Durczynski, Jacek Holubka, Bogdan Siwek, Zofia Siwek, Zbigniew Derdziuk, Waldemar Wierzba, Artur J Jakimiuk

{"title":"Traditional vs novel out-of-office method for collecting cytology and HPV DNA - a comparative study.","authors":"Marcin Januszewski, Laura M Ziuzia-Januszewska, Andrzej Durczynski, Jacek Holubka, Bogdan Siwek, Zofia Siwek, Zbigniew Derdziuk, Waldemar Wierzba, Artur J Jakimiuk","doi":"10.5603/gpl.100294","DOIUrl":"10.5603/gpl.100294","url":null,"abstract":"Objectives: The integration of high-risk human papillomavirus (HPV) detection into cervical cancer screening in Poland aims to improve early detection, yet challenges in coverage and adherence persist. Innovative approaches, like sampling for HPV testing and cytology outside medical settings, have been proposed. This study assesses the feasibility and agreement of results between traditional and novel sampling methods.Material and methods: A cohort of 50 women aged 25-74 underwent HPV DNA and liquid-based cytology sampling both in-office using standard method and outside the medical setting by trained personnel. Samples were analyzed for HPV DNA using Real-Time PCR and cytology according to the Bethesda System.Results: Cytology and HPV DNA positivity rates showed substantial agreement between methods, with almost perfect agreement for high-risk HPV types. Visual assessment of the cervix was successfully conducted in all cases. Preliminary results suggest remote sampling for HPV DNA and cytology is a viable alternative to traditional methods, with the effectiveness in detecting HPV and cytological abnormalities comparable to this reported in literature, offering potential benefits for individuals with mobility limitations or logistical barriers to attending medical appointments.Conclusions: The study highlights the potential role of remote sampling for HPV DNA and cytology in enhancing cervical cancer screening accessibility and adherence. Implementation of such methods could improve coverage, particularly among underserved populations. Further research is needed to validate and optimize these approaches for broader clinical use.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"81-86"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

mTOR inhibitor in the treatment of TFE-positive advanced maligmnant PEComa of the uterus: a case report and literature review. mTOR 抑制剂治疗 TFE 阳性晚期子宫恶性肿瘤：病例报告和文献综述。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-10-29 DOI: 10.5603/gpl.99247

Yaoxiang Zhong, Haikun Yang

{"title":"mTOR inhibitor in the treatment of TFE-positive advanced maligmnant PEComa of the uterus: a case report and literature review.","authors":"Yaoxiang Zhong, Haikun Yang","doi":"10.5603/gpl.99247","DOIUrl":"10.5603/gpl.99247","url":null,"abstract":"Background: The pre- and intra-operative diagnoses of malignant uterine vascular perivascular epithelioid cell tumors (PEComas) can be challenging, for which the literature is limited. Some cases have been shown to have TSC gene mutations or rearrangements of the MiT factor family, resulting in variable responses to mTOR inhibitors. We report a case of a TFE-positive malignant PEComa of the uterus with pulmonary metastases that responded favorably to the mTOR inhibitor, everolimus.Case presentation: A 52-year-old female underwent a total hysterectomy 5 years ago for suspected sub-serosal or broad ligament fibroids. The intraoperative pathologic diagnosis was leiomyosarcoma of the uterus and the postoperative diagnosis was malignant PEComa of the uterus. The patient declined genetic testing and further treatment. In December 2020 the patient presented with a pelvic mass and underwent open abdominal mass resection and pelvic adhesiolysis. The pathologic findings confirmed recurrent malignant PEComa of the uterus. The pulmonary lesions gradually progressed during the follow-up period, so treatment with everolimus was initiated. Close follow-up evaluation for nearly 3 years showed disease remission without recurrence or progression.Conclusion: The patient described herein had a TFE-positive uterine malignant PEComa with lung metastasis and responded well to the mTOR inhibitor, everolimus. Close follow-up in the last 3 years showed remission without recurrence or progression.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"206-213"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of VCare and SecuFix uterine manipulator in total laparoscopic hysterectomy: a prospective randomized trial.

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-02-11 DOI: 10.5603/gpl.101589

Emre Mat, Esra Keles, Pınar Yıldız, Murat Levent Dereli, Fatih Şanlıkan, Gazi Yıldız

{"title":"Comparison of VCare and SecuFix uterine manipulator in total laparoscopic hysterectomy: a prospective randomized trial.","authors":"Emre Mat, Esra Keles, Pınar Yıldız, Murat Levent Dereli, Fatih Şanlıkan, Gazi Yıldız","doi":"10.5603/gpl.101589","DOIUrl":"10.5603/gpl.101589","url":null,"abstract":"Objectives: To compare the Vcare and SecuFix uterine manipulators (UM) used in total laparoscopic hysterectomy (TLH) with regard to operating time, duration of hospital stay, the time for insertion of the manipulator, time for completion of colpotomy, and maintenance of pneumoperitoneum, estimated blood loss, and perioperative complications.Material and methods: This prospective, single-center, randomized controlled trial was conducted on patients who underwent TLH for benign indications between June 2023 and January 2024. Patients were randomized to either the Vcare UM or SecuFix UM group. Both groups were compared for operative time, colpotomy time, intrauterine manipulator insertion time, pneumoperitoneum maintenance, blood loss, complications, and length of hospital stay.Results: A total of 100 patients were enrolled, 50 with VcareUM and 50 with SecuFix UM. SecuFix UM demonstrated shorter colpotomy time (p < 0.001) and better pneumoperitoneum maintenance (p = 0.008) compared to VCare. VCare had shorter insertion time (p = 0.001) but a higher uterine rupture rate (p = 0.001). No significant differences were found in operative time, blood loss, complications, or length of hospital stay (p > 0.05).Conclusions: SecuFix may offer advantages in colpotomy and pneumoperitoneum maintenance during TLH compared to VCare. The Vcare UM demonstrated a shorter insertion time than the SecuFix UMs, yet a higher rate of uterine rupture was observed with its placement.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"168-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of prognostic nutritional status and lipid profile in gestational diabetes. 评估妊娠糖尿病患者的预后营养状况和血脂状况。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-10-16 DOI: 10.5603/gpl.99832

Betül Tokgöz Çakır, Gizem Aktemur, Gulsan Karabay, Zeynep Şeyhanlı, Serap Topkara Sucu, Aslihan Coşkun, Seval Yılmaz Ergani, Hande Esra Koca Yildrim, Yildiz Akadaş Reis, Can Tekin İskender

{"title":"Evaluation of prognostic nutritional status and lipid profile in gestational diabetes.","authors":"Betül Tokgöz Çakır, Gizem Aktemur, Gulsan Karabay, Zeynep Şeyhanlı, Serap Topkara Sucu, Aslihan Coşkun, Seval Yılmaz Ergani, Hande Esra Koca Yildrim, Yildiz Akadaş Reis, Can Tekin İskender","doi":"10.5603/gpl.99832","DOIUrl":"10.5603/gpl.99832","url":null,"abstract":"Objectives: This study aimed to investigate the relationship between controlling nutritional status index (CONUT) and prognostic nutrition index (PNI) scores that are used to evaluate nutritional status and GDM. Also, lipid abnormalities and albumin levels in pregnant women with normal glucose tolerance and GDM were researched.Material and methods: This study was conducted as a retrospective study at Ankara Etlik City Hospital, Turkey. The study included 67 pregnant women with singleton pregnancies (32 pregnant diagnosed with GDM and 35 pregnant known to be normoglycemic).Results: There were no statistical differences between the groups in terms of maternal age, gravidity, parity, history of miscarriage and weight gain during pregnancy. Body mass index (BMI) was higher in the GDM group (p = 0.001). There was no difference in the CONUT score between the groups (p = 0.254). The PNI score was lower in the GDM group (p = 0.003). Of the laboratory data, only fasting blood glucose, triglycerides (TG) and total cholesterol (TC) were statistically significantly higher, and albumin was lower in the GDM group (p = 0.026, p = 0.007, p = 0.003 and p = 0.003, respectively).Conclusions: PNI has the potential to be a useful predictor of GDM, whereas CONUT does not. Low albumin levels and increased TG, and TC in the first trimester seem to be significant in the development of GDM.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"58-64"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0