Ginekologia polska最新文献

{"title":"Association between MMP-9-C1562Tpolymorphism and susceptibility to preeclampsia: a systematic review and meta-analysis.","authors":"Ruihong Lan, Yang Yang, Jie Song, Hong Yang, Ling Wang, Humin Gong","doi":"10.5603/gpl.100274","DOIUrl":"10.5603/gpl.100274","url":null,"abstract":"<p><strong>Objectives: </strong>This meta-analysis aims to explore the association between MMP-9-C1562T polymorphism and susceptibility to preeclampsia (PE).</p><p><strong>Material and methods: </strong>Four English databases were searched to collect relevant records up to April 2024. The pooled odds ratio (OR) was calculated using Stata 15.0.</p><p><strong>Results: </strong>A total of 10 studies were enrolled in our systematic review. The results showed that genotype CT at MMP-9-C1562T locus increased the risk of PE versus genotype TT (Genotype CT vs TT: OR = 2.32, 95% CI: 1.27-4.24, P = 0.006), but no significant differences were found in other gene models (C vs T: OR = 0.88, 95% CI: 0.71-1.08, P = 0.225; Genotype CC vs TT: OR = 1.51, 95% CI: 0.87-2.61, P = 0.139; Genotype CC + CT vs TT: OR = 1.63, 95% CI: 0.95-2.81, P = 0.079; Genotype CC vs CT + TT: OR = 0.80, 95% CI: 0.63-1.03, P = 0.086). Subgroup analysis by ethnicity showed a statistically significant difference in the heterozygous model in China (Genotype CT vs TT: OR = 2.38, 95% CI: 1.15 -4.91, P = 0.019).</p><p><strong>Conclusions: </strong>Association of MMP-9-C1562T polymorphism with susceptibility to PE exists. Specifically, genotype CT increases the risk of PE versus genotype TT, particularly in Caucasian populations.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D and calcium levels related to bone mineral density during pregnancy and postpartum.","authors":"Wiktor Wojczakowski, Konrad Futyma","doi":"10.5603/gpl.102995","DOIUrl":"10.5603/gpl.102995","url":null,"abstract":"<p><p>Bone mineral density (BMD) is crucial for bone strength, with even a modest decrease significantly elevating fracture risk. Calcium imbalance during pregnancy contributes to BMD loss, as maternal stores are mobilized to support fetal skeletal development. Vitamin D deficiency exacerbates this issue, with prevalence rates alarming in various populations. Supplementation with vitamin D and calcium aims to mitigate BMD decline; however, optimal dosing and efficacy remain debated. Studies utilizing innovative diagnostic tools like radiofrequency echographic multi spectrometry (REMS) and quantitative ultrasonometry (QUS) shed light on BMD changes during pregnancy, offering safer alternatives to traditional methods such as dual-energy X-ray absorptiometry (DEXA), prohibited during pregnancy due to fetal radiation risks. Despite methodological challenges, research reveals significant BMD reductions during pregnancy, particularly in weight-bearing bones. In conclusion, maintaining maternal bone health during pregnancy and postpartum is critical, requiring comprehensive monitoring and support. Further research is needed to elucidate optimal strategies for preserving BMD throughout the reproductive lifespan, reducing fracture risk and enhancing maternal well-being.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"613-617"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The outcomes of the 5 mm versus 11 mm primary trocar in gynecologic surgery - randomised study.","authors":"Emin Erhan Dönmez, Zafer Bütün, Eyüpcan Kardas, Fisun Vural","doi":"10.5603/gpl.100621","DOIUrl":"10.5603/gpl.100621","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the effects of using 11 mm trocar and 5 mm trocar as primary ports on postoperative pain in benign gynecological laparoscopic surgeries.</p><p><strong>Material and methods: </strong>The patients were divided into two groups as the primary port, group I (5 mm trocar) and group II (11 mm trocar) by block randomization.</p><p><strong>Results: </strong>In the 5 mm trocar group, postoperative pain score and need for analgesia were less in level I and level II operations. Patient satisfaction was significantly higher in the 5 mm trocar group. The postoperative pain score was higher in patients who had trocar insertion attempts 3 times with the direct trocar method compared to patients with 1 or 2 trocar entry attempts.</p><p><strong>Conclusions: </strong>The use of a 5 mm laparoscope in benign gynecological operations is an advantageous method due to low postoperative pain score, analgesic requirement, and high patient satisfaction.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"496-502"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective analysis of the effect of electronic cardiotocography on selected birth and neonatal variables among 4172 women from a Single Centre in Warsaw, Poland.","authors":"Sylwia Lidia Rychlewicz, Grazyna Baczek, Patryk Rzonca, Piotr Wegrzyn, Agnieszka Uryga, Justyna Teliga-Czajkowska","doi":"10.5603/gpl.103375","DOIUrl":"10.5603/gpl.103375","url":null,"abstract":"<p><strong>Objectives: </strong>Cardiotocography (CTG) is widely used for continuous or intermittent assessment of fetal heart function. This study aimed to compare the effects of continuous and intermittent CTG during labour on selected variables.</p><p><strong>Material and methods: </strong>In a retrospective study, 4172 medical records of Warsaw Hospital (Poland) patients were analysed. The study group consisted of 2111 women with continuous CTG during labour and the control group of 2061 women with intermittent CTG.</p><p><strong>Results: </strong>In the group with intermittent CTG, a higher odds ratio of caesarean section (OR = 1.06, 95% CI = 0.87-1.30), second-degree perineal tear (OR = 1.65, 95% CI = 1.07-2.55),third- and fourth-degree perineal tears (OR = 5.13, 95% CI = 1.12-23.53) and oxygen therapy (OR = 1.76, 95% CI = 1.19-2.59) were noted. In the group with intermittent CTG, a lower odds ratio of a newborn with an Apgar score of ≤ 7 points in the fifth minute of life (OR = 0.34, 95% CI = 0.12-0.94), nCPAP (Nasal Continuous Positive Airway Pressure) (OR = 0.56, 95% CI = 0.36-0.86) and resuscitation (OR = 0.37, 95% CI = 0.17-0.79)) were observed. The analysis shows that in the group of women with intermittent CTG during labour, the odds ratio of abnormal BE result was lower (OR=0.45, 95% CI = 0.21-0.98).</p><p><strong>Conclusions: </strong>Continuous CTG during labour in high-risk women increases the likelihood of instrumental delivery (using vacuum) and perineal incision compared with intermittent CTG. The use of intermittent CTG during labour reduces the number of newborns with Apgar scores ≤ 7 points and decreases the number of neonatal interventions such as nCPAP and resuscitation.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"641-648"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retained intrauterine device as cause of thrombotic thrombocytopenic purpura.","authors":"Mateusz Klimek, Aleksandra Machnik, Monika Bialowas, Krzysztof Nowosielski, Andrzej Witek","doi":"10.5603/gpl.101684","DOIUrl":"10.5603/gpl.101684","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"618-620"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The one-center experience comparing glucose monitoring in patients with gestational diabetes mellitus utilizing flash glucose monitoring (FGM) versus traditional self-blood glucose monitoring (SBGM).","authors":"Magdalena K Kwiatkowska, Marianna Kopka, Nina Cyganek, Bartlomiej Matejko, Magdalena Krawczyk, Przemyslaw Witek, Katarzyna Cyganek","doi":"10.5603/gpl.104033","DOIUrl":"10.5603/gpl.104033","url":null,"abstract":"<p><strong>Introduction: </strong>The most prevalent condition affecting the metabolism of carbohydrates during pregnancy is gestational diabetes mellitus (GDM). Continuous glycemia monitoring systems that use sensors are currently replacing the conventional self-monitoring of glycemia with a glucometer. Poland's insurance coverage has made new technologies possible for continuous glycemia monitoring. Our retrospective study compared the effects of two glycemic measurement techniques on patient preferences and maternal and pediatric clinical outcomes: traditional methods using a glucometer and utilizing a sensor for scanning continuous glycemic monitoring (flash glucose monitoring, or FGM).</p><p><strong>Material and methods: </strong>In a retrospective analysis of 277 women with GDM treated in the Department of Metabolic Diseases, University Hospital in Cracow, Poland, in January 2023 we compared the effectiveness of using of sensor FreeStyle Libra (FGM) vs self-blood glucose monitoring (SBGM) by glucometer in improving clinical maternal outcomes measured by daily insulin dose, body weight gain, mean blood glucose and newborns outcomes assessed by body weight, APGAR score, caesarean sections.</p><p><strong>Results: </strong>We examined 224 women from the SBGM group, 53 from the FGM group, and 277 from the GDM ladies. The SBGM group was diagnosed with GDM later in pregnancy [24 (10-25) vs 11 (8-23.5) weeks; p < 0.001], was admitted at the first pregnancy visit [26 (14-29) vs 20 (12-27) weeks; p = 0.001], and was slightly older [33 (30-36) vs 32 (29-34) years; p = 0,027]. The pre-pregnancy body weight [70 (60-83) vs 67 (59-79) kg; p = 0.358] and the number of pregnancies [2 (1-3) vs 2 (1-3); p = 0.118] did not differ between the two groups. Women who used SMGB gained less weight throughout pregnancy [10 (5.5-13.0) vs 12 (8-14.8) kg; p = 0.0333] and had fewer prenatal checkups [5 (4-7) vs 8 (5-9) weeks; p < 0.001], including fewer teleconsultations [1 (0-3)]. Women in the FGM group received insulin treatment earlier [15 (11.5-27) vs 27 (16-30) week of pregnancy; p < 0,001] and used it more often [52 (98.1%) vs 183 (81.3%); p = 0.005]. There was no significant difference in daily insulin dose per kg of weight [26.5 (11.5-39.2) vs 21 (9-39) U/d; p = 0.325]. The groups did not differ in birth weight [SBGM 3243 ± 485 vs FGM 3331 ± 359 g; p = 0.206] and a gestational week at delivery [38 (38-39) vs 39 (38-39) week; p = 0.092], There was no difference in obstetric outcomes: caesarean sections, preterm births, week of delivery, mean birth weight or prevalence of perinatal complications.</p><p><strong>Conclusions: </strong>When comparing traditional SBGM to flash continuous glucose monitoring in this real-world observation, we have found no changes in the outcomes for mothers and newborns between the groups. There were more teleconsultations for women who used FCGM.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"584-592"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal and neonatal outcomes in dichorionic diamniotic twin pregnancies: a comparison between assisted reproductive technology and spontaneous conception.","authors":"Gizem Berfin Uluutku Bulutlar, Eralp Bulutlar, Büşra Parlak Somuncu, Çetin Kılıççı, Pınar Kumru","doi":"10.5603/gpl.103514","DOIUrl":"10.5603/gpl.103514","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate and compare maternal and neonatal outcomes in dichorionic diamniotic (DCDA) twin pregnancies conceived via assisted reproductive technology (ART) versus those conceived spontaneously (SC).</p><p><strong>Material and methods: </strong>This single-center, retrospective cohort study included 852 DCDA twin pregnancies, with 591 conceived spontaneously (SC group) and 261 conceived via ART (ART group). Maternal and neonatal outcomes were extracted from the hospital's automation system and analyzed using statistical methods, including chi-square and Mantel-Haenszel chi-square tests, to account for potential confounding factors.</p><p><strong>Results: </strong>Our findings indicate that ART twin pregnancies have significantly poorer outcomes compared to SC twin pregnancies. The risk of cerclage application is 12.6 times higher in the ART group. Furthermore, ART pregnancies exhibit a 19.2-fold increased risk of intrahepatic cholestasis of pregnancy (ICP). The rates of preterm birth, including late preterm, moderate preterm, very preterm, and extremely preterm, are significantly higher in the ART group. Moreover, ART pregnancies are associated with higher incidences of very low birth weight (VLBW), NICU admissions, and neonatal death. The ART group also experiences significantly higher rates of gestational diabetes mellitus (GDM), pregnancy-induced hypertension (PIH), postpartum hemorrhage, and cesarean section, with postpartum atony occurring 4 times more frequently.</p><p><strong>Conclusions: </strong>Maternal and neonatal outcomes in ART-conceived DCDA twin pregnancies are markedly worse compared to those conceived spontaneously. The observed disparities underscore the necessity for intensive monitoring and tailored management strategies in ART twin pregnancies. Further research is essential to uncover the mechanisms driving these adverse outcomes.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"553-560"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum emotional disorders - a narrative review.","authors":"Roza Motyka, Urszula Sioma-Markowska","doi":"10.5603/gpl.104124","DOIUrl":"10.5603/gpl.104124","url":null,"abstract":"<p><p>Emotional disorders during pregnancy and the postpartum period affect many women worldwide and present a significant challenge in perinatal care. The first year after childbirth is particularly demanding for a woman's emotional well-being, asitismarked by profound physical, emotional, and social changes. The aim of this article is to review and compare the latest data on the prevalence, risk factors, and treatment options for baby blues and postpartum depression. For this purpose, the electronic databases - including PubMed, NLM, MDPI, Europe PMC, and Google Scholar - were searched for recent English-language articles with full-text availability. The search terms included: postpartum depression, baby blues, maternity blues, postpartum depression prevalence, postpartum depression risk factors, postpartum depression treatment, online psychotherapy, and postpartum depression covid. The review was compiled and evaluated using SANRA (Scale for the Assessment of Narrative Review Articles).</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"607-612"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of USG-MRI and post-natal results of cases with anomalies detected in fetal CNS examination.","authors":"Zafer Bütün, Masum Kayapınar, Gökalp Şenol","doi":"10.5603/gpl.101730","DOIUrl":"10.5603/gpl.101730","url":null,"abstract":"<p><strong>Objectives: </strong>Magnetic resonance imaging (MRI) imaging can be useful when fetal central nervous system (CNS) anomalies are detected by ultrasound (USG). This study aims to compare the findings from USG and MRI with post-natal results in cases of fetal CNS anomalies.</p><p><strong>Material and: </strong>METHODS: This is a retrospective/prospective study that analyzed the records of 55 pregnant women who underwent both fetal MRI and USG and whose birth results were obtained due to suspected CNS abnormalities between 2020 and 2023.</p><p><strong>Results: </strong>Pearson correlation analysis and Blant-Altman analysis showed that USG and MRI results of right lateral ventricle measurement were more similar compared to left lateral ventricle measurement. When the cut-off value for lateral ventricle measurement was 10 mm, there was a difference in the USG and MRI results of only 1 pregnant woman in the right lateral ventricle USG-MRI comparison, whereas no difference was observed in 9 pregnant women in the left lateral ventricle analysis. One pregnant woman with healthy USG results was found to have corpus callosum hypoplasia by MRI and one pregnant woman with posterior fossa anomaly by USG had healthy MRI results. All other measurements showed similar results between USG and MRI.</p><p><strong>Conclusions: </strong>Fetal MRI, when performed with appropriate indications in selected cases evaluated by USG, is useful for measuring the lateral ventricles and detecting various CNS anomalies. The advancing technology of USG and MRI devices, along with the experience of the physicians interpreting these examinations, will always be important.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"570-576"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of uterine anteversion and flexion angles in predicting pain severity during diagnostic hysteroscopy: a prospective cohort study.","authors":"Can Tercan, Emrah Dagdeviren, Ali Selcuk Yeniocak, Sultan Can","doi":"10.5603/gpl.102956","DOIUrl":"10.5603/gpl.102956","url":null,"abstract":"<p><strong>Objectives: </strong>Diagnostic hysteroscopy (DH) is a gold standard diagnostic imaging tool in gynecology. There is insufficient data in the literature regarding the reduction of pain felt during the DH and there is no study in the literature that examines the relationship between the measurement of uterine version or flexion angles and the pain felt during DH procedure. The aim of this study was to investigate the effects of uterine version or flexion angles on pain severity during DH and to identify predictive factors for severe pain experienced during the procedure.</p><p><strong>Material and methods: </strong>This prospective single-center cohort study included patients who were eligible for DH within medical indications. Exclusion criteria comprised menopausal status, congenital uterine anomalies, uterine fibroids larger than 2 cm detected on ultrasonography, suspected malignancy, or retroverted uterus. Before hysteroscopy, all patients underwent transperineal ultrasonography to measure uterine version and flexion angles. Patients were asked to rate their pain levels using a 0-10 numerical visual analog scale (VAS). Patients with VAS scores ≥ 6 were categorized into the severe pain group, while those with scores < 6 were classified into the moderate pain group.</p><p><strong>Results: </strong>The study comprised 98 women undergoing DH. Multivariate binary logistic regression analysis identified anteversion angle and nulliparity as significant predictors of severe pain during DH. The optimal cut-off value for predicting severe pain during DH was identified as 74.5°, providing a sensitivity of 66.7% and specificity of 69.0% [area under curve (AUC) = 0.722, p = 0.001].</p><p><strong>Conclusions: </strong>This study demonstrates that a uterine anteversion angle narrower than 74.5° is associated with severe pain during DH.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"524-531"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}