Ginekologia polskaPub Date : 2025-01-01Epub Date: 2025-01-15DOI: 10.5603/gpl.103103
Joanna Szczudlo-Chrascina, Pawel Bojar, Michal Holecki, Agnieszka Niewiadomska, Katarzyna Steinhof-Radwanska
{"title":"The inflammatory breast cancer mimicker - the SMOLD syndrome - rare complication of smoking.","authors":"Joanna Szczudlo-Chrascina, Pawel Bojar, Michal Holecki, Agnieszka Niewiadomska, Katarzyna Steinhof-Radwanska","doi":"10.5603/gpl.103103","DOIUrl":"10.5603/gpl.103103","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"321-323"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2025-01-01Epub Date: 2024-11-29DOI: 10.5603/gpl.102062
Aleksandra Juras, Tomasz Wloch, Wojciech Cnota, Agata Wloch
{"title":"Cardiovascular profile score (CVPS) and selected cardiac parameters in fetuses with Vein of Galen malformation.","authors":"Aleksandra Juras, Tomasz Wloch, Wojciech Cnota, Agata Wloch","doi":"10.5603/gpl.102062","DOIUrl":"10.5603/gpl.102062","url":null,"abstract":"<p><strong>Objectives: </strong>Vein of Galen Malformation (VGAM) is a rare congenital cerebrovascular anomaly. Early detection and monitoring of concurrent fetal heart failure in VGAM are crucial for improving outcomes. The study aims to evaluate heart anatomy, systolic and diastolic heart function, and indicators of heart failure in fetuses referred to a tertiary center due to VGAM detected in the second or third trimester.</p><p><strong>Material and methods: </strong>This single-center retrospective study of echocardiographic data from five fetuses with VGAM examined between 2008 and 2023. Parameters analyzed included gestational age, reason for referral, cardiovascular profile score (CVPS), systolic and diastolic heart function and selected cardiac parameters RESULTS: Cardiomegaly as a sign of congestive heart failure was the main reason for referral most of the fetuses (4/5 - 80%) diagnosed later as VGAM in our center. Abnormal cerebral vessel flow was visualized in all cases, with normal umbilical arterial flow. Three fetuses were treated prenatally with digoxin due to congestive heart failure. Monophasic tricuspid valve inflow and decreased shortening fraction (SF) were observed in three fetuses (60%) at the time of diagnosis. CVPS scores ranged from 2 to 10, correlating with the severity of cardiac compromise. All five patients demised, three died in utero, and two shortly after birth.</p><p><strong>Conclusions: </strong>This study emphasizes the severe cardiac implications of VGAM detected in utero and the need for early and comprehensive fetal assessment. Despite early diagnosis, outcomes remain poor, necessitating further research into effective prenatal treatments and management protocols to enhance survival for affected fetuses.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"355-361"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2025-01-01Epub Date: 2025-03-12DOI: 10.5603/gpl.102733
Tian Zheng, Jia Li, Jing Chao, Hong Lian Wang, Ying Hui, Lan Shen
{"title":"Nonpharmacological mental health interventions for adolescent patients with polycystic ovary syndrome: a scoping review.","authors":"Tian Zheng, Jia Li, Jing Chao, Hong Lian Wang, Ying Hui, Lan Shen","doi":"10.5603/gpl.102733","DOIUrl":"10.5603/gpl.102733","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to summarize nonpharmacological mental health interventions that are beneficial for adolescent patients with polycystic ovary syndrome (PCOS) and to identify the limitations of existing studies.</p><p><strong>Material and methods: </strong>Following the recommendations of the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-SCR), we conducted a scoping review of nonpharmacological interventions aimed at improving mental health in adolescents with PCOS.</p><p><strong>Results: </strong>Six randomized controlled trials (RCTs), two quasiexperimental studies, two case reports, one prospective study, one predictive correlation study, and one field trial study were included, resulting in 13 articles. Nonpharmacological interventions encompass a range of psychotherapies, dietary modifications, physical exercise, and traditional Chinese medicine therapies. Except for one study that has not yet reported findings, all included studies reported significant improvements in patients' mental health through nonpharmacological interventions.</p><p><strong>Conclusions: </strong>The evidence summarized in this study suggests that nonpharmacological interventions may be efficacious in improving the mental well-being of adolescent patients with PCOS. However, existing studies have limitations, including small sample sizes, the limited use of outcome indicators, and a lack of postintervention follow-up evaluations. Therefore, further RCTs should be conducted to validate the effectiveness and safety of current or alternative nonpharmacological interventions.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"405-413"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2025-01-01Epub Date: 2024-10-29DOI: 10.5603/gpl.99247
Yaoxiang Zhong, Haikun Yang
{"title":"mTOR inhibitor in the treatment of TFE-positive advanced maligmnant PEComa of the uterus: a case report and literature review.","authors":"Yaoxiang Zhong, Haikun Yang","doi":"10.5603/gpl.99247","DOIUrl":"10.5603/gpl.99247","url":null,"abstract":"<p><strong>Background: </strong>The pre- and intra-operative diagnoses of malignant uterine vascular perivascular epithelioid cell tumors (PEComas) can be challenging, for which the literature is limited. Some cases have been shown to have TSC gene mutations or rearrangements of the MiT factor family, resulting in variable responses to mTOR inhibitors. We report a case of a TFE-positive malignant PEComa of the uterus with pulmonary metastases that responded favorably to the mTOR inhibitor, everolimus.</p><p><strong>Case presentation: </strong>A 52-year-old female underwent a total hysterectomy 5 years ago for suspected sub-serosal or broad ligament fibroids. The intraoperative pathologic diagnosis was leiomyosarcoma of the uterus and the postoperative diagnosis was malignant PEComa of the uterus. The patient declined genetic testing and further treatment. In December 2020 the patient presented with a pelvic mass and underwent open abdominal mass resection and pelvic adhesiolysis. The pathologic findings confirmed recurrent malignant PEComa of the uterus. The pulmonary lesions gradually progressed during the follow-up period, so treatment with everolimus was initiated. Close follow-up evaluation for nearly 3 years showed disease remission without recurrence or progression.</p><p><strong>Conclusion: </strong>The patient described herein had a TFE-positive uterine malignant PEComa with lung metastasis and responded well to the mTOR inhibitor, everolimus. Close follow-up in the last 3 years showed remission without recurrence or progression.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"206-213"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modified laparoscopic sacrocolpopexy for advanced posterior vaginal wall prolapse: a 3-year prospective study.","authors":"Yifan Yin, Yufang Xia, Shujun Ji, Enhui Guo, Chen Chen, Yanhui Lou","doi":"10.5603/gpl.100017","DOIUrl":"10.5603/gpl.100017","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate and validate the safety and efficacy of modified laparoscopic sacrocolpopexy for advanced posterior vaginal wall prolapse at up to 3 years of follow-up.</p><p><strong>Material and methods: </strong>As a prospective observational study, we collected 56 cases with advanced posterior vaginal wall prolapse and performed modified laparoscopic sacrocolpopexy (MLSC) with self-cut mesh. The main improvement is the cutting and fixing of the mesh. Patients were followed up at 6, 12, 24 and 36 months. The main indicators of follow-up were postoperative anatomic success rate and Pelvic organ prolapse quantitation (POP-Q) score, and secondary indicators were related to quality-of-life scales and postoperative complication rates.</p><p><strong>Results: </strong>All patients completed the operation through minimally invasive surgery, and there were no vital organs and blood vessel damage during the operation. The mean age was (58.32 ± 7.63) years. There was no recurrence of stage I or lower during the follow-up maximum of 36 months (median 24 months), and the anatomic success rate was 100%. The quality-of-life scores improved significantly (p < 0.001) and the quality of sexual life was not affected (p = 0.5). There was 1 case of continuous vaginal mesh exposure at 12 months (2.86%) and 1 case of severe infection with poor healing of vaginal stump within 6 months (1.79%). No one had urinary incontinence (UI) requiring reoperation.</p><p><strong>Conclusions: </strong>In patients with advanced posterior vaginal wall prolapse, MLSC can provide good and durable pelvic floor anatomical recovery and functional outcomes with no specific complications.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"87-95"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2025-01-01Epub Date: 2025-01-15DOI: 10.5603/gpl.103029
Monika Bekiesinska-Figatowska, Marta Dziuba, Krystyna Ignaciuk, Malgorzata Gajewska, Tomasz Sarosiek, Jaroslaw B Cwikla
{"title":"Pelvic splenosis infiltrating the uterus and ovary.","authors":"Monika Bekiesinska-Figatowska, Marta Dziuba, Krystyna Ignaciuk, Malgorzata Gajewska, Tomasz Sarosiek, Jaroslaw B Cwikla","doi":"10.5603/gpl.103029","DOIUrl":"10.5603/gpl.103029","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"516-517"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Major opinion about motherhood among women with Turner syndrome.","authors":"Malgorzata Wiecek, Wiktoria Kempinska, Aneta Gawlik-Starzyk","doi":"10.5603/gpl.102148","DOIUrl":"10.5603/gpl.102148","url":null,"abstract":"<p><strong>Objectives: </strong>Turner syndrome (TS) is associated with ovarian dysgenesis leading to infertility in most of the cases. There are some options for fertility preservation (FP) in patients with sufficient follicle numbers. The most recently studied are oocyte and ovarian tissue preservation. Due to premature ovarian failure among TS girls, the procedure should be performed as early as possible. The aim of this study is to gain the opinions of women with TS about motherhood based on the web-survey.</p><p><strong>Material and methods: </strong>The survey, hosted on SurveyMonkey.com, targeted women over 18 years with TS. It comprised 16 single-choice questions, ensuring anonymity and consent for data usage.</p><p><strong>Results: </strong>The answers of a total of 152 women were analyzed. When asked if they had discussed motherhood options with their physicians, 72/152 of the participants responded negatively. Asked about the desire of maternity, 85/152 expressed a desire to have children. 5/152 had biological children from spontaneous pregnancies, 5/152 had biological children through oocyte donation, 1/152 through embryo donation, and 12/152 had adopted children. 75/150 respondents answered yes to the question of whether they desired to use ovarian tissues if they had been preserved during adolescence.</p><p><strong>Conclusions: </strong>The findings suggest that a significant number of women with TS who aspire to become mothers would be inclined to use preserved cells if this option were available. This underscores the necessity for further exploration of FP techniques for individuals with TS.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"476-481"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2025-01-01Epub Date: 2024-11-29DOI: 10.5603/gpl.102668
Katarzyna Zych-Krekora, Oskar Sylwestrzak, Milena Skibinska, Maciej Ziebakowski, Michal Krekora
{"title":"ADAM 12 as a prognostic factor of pregnancy induced hypertension - preliminary study.","authors":"Katarzyna Zych-Krekora, Oskar Sylwestrzak, Milena Skibinska, Maciej Ziebakowski, Michal Krekora","doi":"10.5603/gpl.102668","DOIUrl":"10.5603/gpl.102668","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"230-232"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2025-01-01Epub Date: 2025-01-15DOI: 10.5603/gpl.96519
Izabela Uzar, Anna Bogacz, Elzbieta Sowinska-Przepiera, Anhelli Syrenicz, Adam Kaminski, Marlena Wolek, Boguslaw Czerny
{"title":"Assessment of the impact of VDR polymorphisms on selected hormonal, metabolic and mineral balance markers in young women with hyperandrogenism.","authors":"Izabela Uzar, Anna Bogacz, Elzbieta Sowinska-Przepiera, Anhelli Syrenicz, Adam Kaminski, Marlena Wolek, Boguslaw Czerny","doi":"10.5603/gpl.96519","DOIUrl":"10.5603/gpl.96519","url":null,"abstract":"<p><strong>Objectives: </strong>Hyperandrogenism is a frequently recognized endocrine imbalance in which there is excessive production of androgens. The purpose of the study was to investigate the impact of vitamin D receptor (VDR) gene polymorphisms on chosen bone metabolism and biochemical parameters in women with hyperandrogenism.</p><p><strong>Material and methods: </strong>Eighty young females with hyperandrogenism were enrolled in the study, in whom selected parameters of bone turnover, endocrine and metabolic parameters were determined. Two polymorphisms of the VDR gene were analyzed: rs731236 (TaqI) and rs1544410 (BsmI), using real-time polymerase chain reaction (PCR). Statistical tests were performed in this research with the program SPSS Statistics 17.0 for Windows.</p><p><strong>Results: </strong>The rs731236 and rs1544410 polymorphisms of the VDR gene turned out to be statistically significantly related to the concentration of insulin determined in the 60 'glucose tolerance test. There was no relationship between the studied polymorphisms of the VDR gene and the determined parameters of bone metabolism and other biochemical parameters.</p><p><strong>Conclusions: </strong>The research presented that VDR gene variants may influence disturbances in carbohydrate metabolism in young women with hyperandrogenism.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"109-118"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ginekologia polskaPub Date : 2025-01-01Epub Date: 2024-11-29DOI: 10.5603/gpl.102620
Marcin Misiek, Agnieszka Picheta, Kaja Michalczyk, Tomasz Kluz, Andrzej Wrobel, Rafal Stojko, Anita Chudecka-Glaz
{"title":"FIGO 2023 - too soon or just in time? Evolution or a revolution? Review of the newest endometrial cancer staging classification.","authors":"Marcin Misiek, Agnieszka Picheta, Kaja Michalczyk, Tomasz Kluz, Andrzej Wrobel, Rafal Stojko, Anita Chudecka-Glaz","doi":"10.5603/gpl.102620","DOIUrl":"10.5603/gpl.102620","url":null,"abstract":"<p><p>The FIGO staging system is an integral part of the therapeutic and treatment process in female genital tumors. It cements the knowledge gained to date to plan patient treatment prognosis and the course of the disease and compare treatment outcomes between centers in the most individualized yet systematic way. In response to these assumptions, the FIGO Committee on Gynaecological Oncology updated the endometrial cancer staging classification in June 2023. The new endometrial cancer staging classification includes multiple clinicopathological prognostic factors and molecular findings for the first time. In this review, we summarize the differences between the new and the old FIGO classification and comment on its everyday real-world application.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"314-320"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}