Ginekologia polska最新文献_第10页

IL-6, IL-10 and TNF-α gene polymorphisms in preeclampsia: a case-control study in a Mexican population. 子痫前期患者IL-6、IL-10和TNF-α基因多态性的病例对照研究。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2023-10-16 DOI: 10.5603/gpl.94272

Carlos Ernesto Mora Palazuelos, Elsa Maribel Aguilar Medina, Mariana Melisa Avendaño Felix, Rosalio Ramos Payán, Mercedes Bermudez Cortez, Leticia Lara Avila, Adrian Herrera Salazar, Joel Murillo Llanes, Guzmán Sanchez-Schmitz, Jose Geovanni Romero Quintana

{"title":"IL-6, IL-10 and TNF-α gene polymorphisms in preeclampsia: a case-control study in a Mexican population.","authors":"Carlos Ernesto Mora Palazuelos, Elsa Maribel Aguilar Medina, Mariana Melisa Avendaño Felix, Rosalio Ramos Payán, Mercedes Bermudez Cortez, Leticia Lara Avila, Adrian Herrera Salazar, Joel Murillo Llanes, Guzmán Sanchez-Schmitz, Jose Geovanni Romero Quintana","doi":"10.5603/gpl.94272","DOIUrl":"10.5603/gpl.94272","url":null,"abstract":"Objectives: We focused our study on examining the genotype and allele frequency of IL-6 (rs1800795), TNF-α (rs1800629) and IL-10 (rs1800872) single nucleotide polymorphisms (SNP) on preeclampsia (PE) diagnosed Mexican pregnant women.Material and methods: A case-control study was designed including 86 preeclampsia patients and 100 normotensives pregnancies from Women's Hospital of Culiacan, Mexico. Genotyping of IL-6, TNF-α and IL-10 was performed using TaqMan SNP Genotyping.Results: Not significant association was found between development of PE and genotypic (p > 0.05) and allelic (p > 0.05) frequencies of IL-6, TNF-α and IL-10 SNPs. Genotype distributions of IL-6 (p = 0.599), TNF-α (p = 0.721) and IL-10 (p = 0.761) polymorphisms in the two groups were in agreement with Hardy-Weinberg equilibrium.Conclusions: According to the findings, the IL-6, TNF-α and IL-10 SNPs are not exponents of susceptibility to developing PE.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"108-113"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of intravenous nicardipine followed by oral labetalol in combination with nifedipine controlled-release tablet on severe peripartum hypertension. 静脉注射尼卡地平后口服拉贝洛尔联合硝苯地平控释片对重度围产期高血压的影响。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2024-02-09 DOI: 10.5603/gpl.97752

Lan Lan, Yunsheng Yan, Haifeng Qi, Jiali Qin, Lan Li, Shengwen Gan, Ruoxuan Zhang, Yaozong Zhang

{"title":"Effects of intravenous nicardipine followed by oral labetalol in combination with nifedipine controlled-release tablet on severe peripartum hypertension.","authors":"Lan Lan, Yunsheng Yan, Haifeng Qi, Jiali Qin, Lan Li, Shengwen Gan, Ruoxuan Zhang, Yaozong Zhang","doi":"10.5603/gpl.97752","DOIUrl":"10.5603/gpl.97752","url":null,"abstract":"Objectives: To investigate the effects of intravenous nicardipine as initial therapy and oral labetalol combined with nifedipine controlled-release tablet as subsequent treatment of severe peripartum hypertension.Material and methods: Intravenous nicardipine was delivered as the initial treatment, after the target blood pressure (BP) had been achieved, oral labetalol was used to maintain the target BP. If oral labetalol failed to maintain the target BP, oral labetalol combined with nifedipine controlled-release tablet was used.Results: A total number of 131 patients were enrolled. The target BP (BP < 140/90 mmHg) was achieved in all patients within 60 minutes by intravenous nicardipine. After receiving labetalol orally, the target BP was maintained in nine patients. However, in 104 patients, we had to combine oral labetalol and nifedipine controlled-release tablet due to re-elevation of their systolic BP to 140-159 mmHg. In 18 patients, we restarted intravenous nicardipine because their systolic BP re-elevated above 160 mm Hg. Among the 104 patients who received oral labetalol and nifedipine controlled-release tablet, the target BP was achieved and maintained in 96 patients, and eight patients had to restart nicardipine. Of the total number of 26 patients in whom intravenous nicardipine was resumed, the target BP was successfully maintained in 22 patients with oral labetalol combined with nifedipine controlled-release tablet.Conclusions: Intravenous nicardipine rapidly and safely lowered severe peripartum hypertension. As subsequent therapy, oral labetalol combined with nifedipine controlled-release tablet protocol may be applied to effectively maintain a target BP.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"536-543"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of the cosmetic appearance of skin scar after caesarean section - part II physiotherapy practice. 优化剖腹产后皮肤疤痕的外观--第二部分物理治疗实践。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2024-02-09 DOI: 10.5603/gpl.98523

Agata Michalska, Marta Mierzwa-Molenda, Karol Bielasik, Justyna Pogorzelska, Daniel P Wolder, Grzegorz Swiercz

引用次数: 0

The discrepancy distribution of macrophage subsets in preeclampsia placenta with or without fetal growth restriction from a small cohort. 从一个小型队列中发现，子痫前期胎盘中的巨噬细胞亚群分布存在差异，有的伴有胎儿生长受限，有的不伴有胎儿生长受限。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2024-02-09 DOI: 10.5603/gpl.97942

Wenhui Song, Fengjiao Wang, Xia Li, Fangfang Liu, Tianxiao Yu, Xizhenzi Fan, Mingwei Li, Qing Guo

{"title":"The discrepancy distribution of macrophage subsets in preeclampsia placenta with or without fetal growth restriction from a small cohort.","authors":"Wenhui Song, Fengjiao Wang, Xia Li, Fangfang Liu, Tianxiao Yu, Xizhenzi Fan, Mingwei Li, Qing Guo","doi":"10.5603/gpl.97942","DOIUrl":"10.5603/gpl.97942","url":null,"abstract":"Objectives: To identify the effect of distribution characteristic of macrophages on placental function and angiogenesis in pregnancies with preeclampsia (PE) in presence of fetal growth restriction (FGR) or preeclampsia without FGR.Material and methods: The study tested the hypothesis that there was association between distribution characteristic of macrophage subsets (marked by CD68, CD163, respectively) and placental capillary development, leading to placental dysfunction in PE pregnancies with FGR (n = 36). Changes in placental parameters related with efficiency and angiogenesis and macrophage phenotypes (CD68 and CD163) were evaluated by immunohistochemistry. Pearson correlation analysis was performed to analysis the association between macrophage phenotype and placental function as well the CD34 staining, respectively. Additionally, the localization of CD68 and CD163 was assessed by using immunoflurorescence staining.Results: Pearson correlation analysis had shown the positive association between CD68 expression and microvessel formation and the reverse linear relationship between CD163 staining and placental sufficiency in PE + FGR placenta. The co-localization of CD163 and CD34 may pointed to the compensatory role of CD163 distribution involved in prompting neovascularization.Conclusions: The association between disturbed distribution of macrophages and placental efficiency and angiogenesis were only found in PE with FGR not in PE pregnancies without FGR, underlying the discrepancy role of macrophage subsets depending on the clinical phenotype of PE pregnancies.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"677-686"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative tools to assess pelvic floor muscle function - systematic review. 评估盆底肌肉功能的定量工具--系统综述。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2024-03-20 DOI: 10.5603/gpl.90873

Dominika Michalik, Urszula Herman, Klaudia Stangel-Wojcikiewicz

{"title":"Quantitative tools to assess pelvic floor muscle function - systematic review.","authors":"Dominika Michalik, Urszula Herman, Klaudia Stangel-Wojcikiewicz","doi":"10.5603/gpl.90873","DOIUrl":"10.5603/gpl.90873","url":null,"abstract":"Objectives: Urinary incontinence is pelvic floor muscles dysfunction, most often caused by a weakening of their strength. There are no guidelines on how to evaluate pelvic floor muscle function. Palpation is the most popular method of assessing pelvic floor muscle function, but it is subjective. The aim of the study was to review the objective methods used in the assessment of pelvic floor muscle function in women with urinary incontinence.Material and methods: A systematic literature review of the PubMed database was performed using the following keywords: [\"Pelvic Floor\" (mh)] AND [(\"Pelvic Floor Disorders\" (mh)] OR [\"Urinary Incontinence\" (mh)]. The search was limited to English-language works published from 2011 to 2021. The inclusion criteria were interventional studies in which the pelvic floor muscle function of women with urinary incontinence was assessed using quantitative tools. Methods that cannot be used in the clinic were excluded from the analysis.Results: Fifty-two articles were included in the analysis and five methods assessing the function of pelvic floor muscle were distinguished: manometry, electromyography (EMG), ultrasonography (USG), dynamometry, accelerometry.Conclusions: Manometry, EMG and USG are the most common objective methods of assessing pelvic floor muscle function. When taking measurements, it is important to choose the right position of the patient. The use of objective tools to assess the function of the pelvic floor muscle and obtaining quantitative and/or qualitative data allows us to precisely diagnose and monitor the treatment and rehabilitation progress.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"718-728"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tight versus less tight 1-hour postprandial glycemic target in women with gestational diabetes mellitus - a single-center cohort study. 妊娠糖尿病妇女餐后 1 小时血糖目标过紧与过松--一项单中心队列研究。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2024-05-08 DOI: 10.5603/gpl.98992

Michal Kania, Magdalena Wilk, Iga Grabarczyk, Magdalena Kwiatkowska, Katarzyna Cyganek, Maciej T Malecki, Magdalena Szopa

{"title":"Tight versus less tight 1-hour postprandial glycemic target in women with gestational diabetes mellitus - a single-center cohort study.","authors":"Michal Kania, Magdalena Wilk, Iga Grabarczyk, Magdalena Kwiatkowska, Katarzyna Cyganek, Maciej T Malecki, Magdalena Szopa","doi":"10.5603/gpl.98992","DOIUrl":"10.5603/gpl.98992","url":null,"abstract":"Objectives: We aimed to assess the impact of the change of 1-hour postprandial glycemic target from < 6.7 mmol/L (120 mg/dL) to < 7.8 mmol/L (140 mg/dL) on gestational diabetes mellitus (GDM) treatment and pregnancy outcomes.Material and methods: In a retrospective analysis of 1021 GDM patients from the Department of Metabolic Diseases, University Hospital in Cracow, Poland, we compared insulin therapy regimens and pregnancy outcomes between women admitted in 2014-2016 (before the change) and in 2018-2019 (after it).Results: A total of 377 patients were admitted between 2014 and 2016 (TIGHT group) and 644 between 2018 and 2019 (LESS TIGHT group). Women from the LESS TIGHT group were older (32 vs 30 years, p < 0.001) and gained less weight during pregnancy (7.0 vs 9.0 kg, p < 0.001). There was no change in the frequency of any insulin therapy (51.6% vs 56.1%, p = 0.168). In the LESS TIGHT group, the basal insulin-only model was used more frequently (32.5% vs 10.2%, p < 0.001), while the prandial insulin and basal-bolus model less frequently (23.6% vs 42.6% and 21.4% vs 36.7%, p < 0.001, respectively) than in the TIGHT group. There were no differences in the frequency of cesarean sections, preterm births, Hbd of delivery, mean birth weight or prevalence of perinatal complications.Conclusions: Less tight glycemic targets in women with GDM, compared to tighter targets, were associated with less frequent use of prandial insulin, with insulin therapy often limited to basal administration. The change in glycemic targets did not affect the prevalence of adverse pregnancy outcomes, providing evidence supporting new recommendations.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"607-614"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteopontin as a marker of endometriosis - the current state of knowledge. 骨桥蛋白作为子宫内膜异位症的标志物-目前的知识状况。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2023-09-25 DOI: 10.5603/gpl.86232

Joanna Figula, Rafal M Baran, Robert Jach

引用次数: 0

Eradication of cervical canal colonization associated with prophylactic cervical cerclage: the look further study. 根除与预防性宫颈环扎术相关的宫颈管定植：前瞻性的进一步研究。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2023-10-16 DOI: 10.5603/gpl.96507

Natalia Sroka-Ostrowska, Radoslaw Pietrzak, Dominika Pykalo-Gawinska, Julia Zareba-Szczudlik, Krzysztof Czajkowski, Ewa Romejko-Wolniewicz

{"title":"Eradication of cervical canal colonization associated with prophylactic cervical cerclage: the look further study.","authors":"Natalia Sroka-Ostrowska, Radoslaw Pietrzak, Dominika Pykalo-Gawinska, Julia Zareba-Szczudlik, Krzysztof Czajkowski, Ewa Romejko-Wolniewicz","doi":"10.5603/gpl.96507","DOIUrl":"10.5603/gpl.96507","url":null,"abstract":"Objectives: The perioperative management of the cervical cerclage procedure is not unified. In general population controlling microbiome cervical status does not affect obstetric outcomes, but it might be beneficial in patients with cervical insufficiency. The aim of our study was to present the obstetric, neonatal and pediatric outcomes of patients undergoing the cervical cerclage placement procedure in our obstetric department using a regimen of care that includes control of the microbiological status of the cervix and elimination of the pathogens detected.Material and methods: Thirty-five patients undergoing cervical cerclage in the 2nd Department of Obstetrics and Gynecology, Medical University of Warsaw, were included in the study. The procedure was performed only after receiving a negative culture from the cervical canal.Results: Thirty-one (88.6%) patients delivered after the 34th and twenty-eight (80.0%) after the 37th week of gestation. The colonization of the genital tract was present in 31% of patients prior to the procedure, in 42% of patients - during the subsequent pregnancy course and in 48% of patients - before delivery. A total of 85% of patients who had miscarriage or delivered prematurely had abnormal cervical cultures. In patients with normal cervical cultures, and 91.7% of women delivered at term. No abnormalities in children's development were found.Conclusions: Controlling microbiological status of the cervical canal results in better or similar outcomes to those reported by other authors in terms of obstetric and neonatal outcomes. Active eradication of the reproductive tract colonization potentially increases the effectiveness of the cervical cerclage placement.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"92-98"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal diagnosis of isolated total anomalous pulmonary venous connection (TAPVC) to coronary sinus. 冠状窦孤立性完全异常肺静脉连接（TAPVC）的产前诊断。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2023-10-16 DOI: 10.5603/gpl.96430

Anna Wojtowicz, Beata Zaluska-Pitak, Magdalena Juszczak, Hubert Huras, Sebastian Goreczny

引用次数: 0

Expression of B7-H4 in endometrial cancer and its impact on patients' prognosis. B7-H4在癌症中的表达及其对预后的影响。

Ginekologia polska Pub Date : 2024-01-01 Epub Date: 2023-10-24 DOI: 10.5603/gpl.96605

Katarzyna Gorzelnik, Anna Wasaznik-Jedras, Lukasz Wicherek, Sebastian Szubert

{"title":"Expression of B7-H4 in endometrial cancer and its impact on patients' prognosis.","authors":"Katarzyna Gorzelnik, Anna Wasaznik-Jedras, Lukasz Wicherek, Sebastian Szubert","doi":"10.5603/gpl.96605","DOIUrl":"10.5603/gpl.96605","url":null,"abstract":"Objectives: The aim of the study was to evaluate the B7-H4 expression in endometrial cancer cells and to investigate its relationship with patient prognosis and clinicopathological features of the disease.Material and methods: We performed a single-center, retrospective cohort study that included endometrial cancer patients treated between 2012 and 2019. B7-H4 expression in specimens obtained from 63 patients was examined by immunohistochemical staining. The evaluation of B7H4 immunoreactivity was assessed using Immunoreactivity Scoring (IRS) system.Results: B7-H4 reactivity was observed in all, except one, endometrial cancer patients (98%). Staining intensity: no reaction in one case, weak in 16 (24%) patients, moderate in 25 (37%), and strong in 22 (35%). Twenty-nine (46%) patients showed B7-H4 immunoreactivity in more than 60% of cells, while, in 18 (29%) cases and 16 (25%) patients, the percentages were 30-60% and < 30% respectively. Median IRS was 2 (range 0-6). We found a significantly worse overall survival (OS) rate for patients with high versus low B7-H4 IRS (p = 0.03), however, in multivariate analysis, the difference in patient survival was close to the significance level (p = 0.052). B7-H4 expression was not related to histopathological type of the tumor, tumor grade, lymph node metastases, or the FIGO stage of the disease.Conclusions: Our result suggests that B7-H4 expression might be a useful prognostic factor in endometrial cancer.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"252-258"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49695363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0