Ginekologia polska最新文献_第10页

Collagen and elastin differences in vulvar tissue of women with lichen planus, lichen sclerosus and healthy women. 扁平地衣、硬化地衣与健康女性外阴组织中胶原蛋白和弹性蛋白的差异。

Ginekologia polska Pub Date : 2023-11-23 DOI: 10.5603/gpl.95974

Adrianna Marzec, Aleksandra Augusciak-Duma, Dominika Lubik-Lejawka, Anita Olejek, Iwona Gabriel

{"title":"Collagen and elastin differences in vulvar tissue of women with lichen planus, lichen sclerosus and healthy women.","authors":"Adrianna Marzec, Aleksandra Augusciak-Duma, Dominika Lubik-Lejawka, Anita Olejek, Iwona Gabriel","doi":"10.5603/gpl.95974","DOIUrl":"https://doi.org/10.5603/gpl.95974","url":null,"abstract":"Objectives: Lichen sclerosus and lichen planus are two debilitating dermatoses. Their etiology remains unknown. Skin changes resulting from these disorders are important to understand, so we can provide targeted treatment to patients. We examined the differences in collagen (COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, COL5A3) and elastin (ELN) expression between vulvar tissue of women with lichen planus, lichen sclerosus and healthy women.Material and methods: Vulvar tissue was taken from areas affected by lichen planus or lichen sclerosus. In healthy controls, we biopsied vulva at five and eight o'clock in a standardized manner. The tissue was simultaneously sent for pathological and genetic analysis. When either lichen planus or sclerosus or healthy tissue was confirmed by pathologist, we processed the genetic sample. RNA was isolated, transcribed and gene expression was analyzed using Real Time Custom Panel 96-16 and LightCycler 480 Probe Master. Kolmogorov-Smirnov test was employed to determine if the data on the population show normal distribution. For genes with normal distribution, t-Test was employed and for those lacking normality, we used Mann-Whitney 1-tail test. The threshold for p-value was set less than 0.05.Results: Thirty-nine vulvar samples were examined. The mean expression of COL1A1 was 11.13, COL1A2 was 6.72, COL3A1 was 8.43, COL5A1 was 11.91, COL5A2 was 10.62 and COL5A3 was 12.79. The mean expression of elastin (ELN) was 13,13. We found statistically significant difference in expression of collagen (COL1A2) and elastin (ELN) between healthy controls and patients with lichen planus (p = 0.4). We did not find differences for other genes (p < 0.05).Conclusions: Collagen and elastin are differentially expressed between patients with lichen planus and healthy controls.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138296853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Basic hope, level of stress and strategies used to cope with stress after miscarriage during hospitalization and 3 months after its completion. 基本希望、压力水平和应对流产住院期间和流产结束后3个月的压力的策略。

Ginekologia polska Pub Date : 2023-11-23 DOI: 10.5603/gpl.96215

Katarzyna Bialek, Marcin Sadowski, Olga Adamczyk-Gruszka, Jakub Mlodawski, Grzegorz Swiercz

{"title":"Basic hope, level of stress and strategies used to cope with stress after miscarriage during hospitalization and 3 months after its completion.","authors":"Katarzyna Bialek, Marcin Sadowski, Olga Adamczyk-Gruszka, Jakub Mlodawski, Grzegorz Swiercz","doi":"10.5603/gpl.96215","DOIUrl":"https://doi.org/10.5603/gpl.96215","url":null,"abstract":"Objectives: Basic hope is important for successfully coping with, and adapting to, difficult situations. The aim of the study was to determine the level of stress and basic hope and identify the associated coping processes in women after miscarriage during hospitalization and threemonths after discharge.Material and methods: Atotal of 161women hospitalized due to miscarriage were included. To evaluate the level of stress, basic hope and coping strategies, the following standardized questionnaires were used: the Perceived Stress Scale (PSS-10), the Inventory to Measure Coping Strategies with Stress (Mini-COPE) and the Basic Hope Inventory (BHI-12).Results: 110 patients declared high levels of stress during hospitalization and 80 claimed the same three months after discharge. The level of stress decreased after three months (p < 0.001). Adaptive stress-coping strategies were employed more frequently than maladaptive stress-coping strategies. During hospitalization, the most frequently used strategies were acceptance and seeking emotional support; with planning, acceptance, seeking emotional and instrumental support being used three months after discharge. The sense of basic hope increased after three months (p < 0.001). The level of the sense of basic hope correlates significantly (p < 0.001) and negatively (r ˂ 0) with the severity of stress symptoms during and after the hospital stay.Conclusions: The sense of basic hope increased significantly after three months in relation to the level experienced during the hospitalization period, and the intensity of stress decreased. Preventive women-oriented interventions are needed to minimize the risk of post-traumatic stress disorder.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138296852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic imaging of ovarian masses and not only - beyond ultrasound. 卵巢肿块的诊断成像不仅限于超声。

Ginekologia polska Pub Date : 2023-11-23 DOI: 10.5603/gpl.96921

Monika Bekiesinska-Figatowska

引用次数: 0

Transvaginal natural orifice endoscopic surgery (vNOTES) for elderly patients. 老年患者经阴道自然口内镜手术（vNOTES）。

Ginekologia polska Pub Date : 2023-10-24 DOI: 10.5603/gpl.95911

Emre Mat, Pınar Yıldız, Rezzan Berna Temoçin, Özgür Kartal, Esra Keles

{"title":"Transvaginal natural orifice endoscopic surgery (vNOTES) for elderly patients.","authors":"Emre Mat, Pınar Yıldız, Rezzan Berna Temoçin, Özgür Kartal, Esra Keles","doi":"10.5603/gpl.95911","DOIUrl":"https://doi.org/10.5603/gpl.95911","url":null,"abstract":"Objectives: To evaluate the feasibility and safety of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) in patients 70 years and over.Material and methods: The study consisted of eleven patients aged 70 and over who underwent vNOTES for a variety of gynaecological indications at a tertiary referral hospital. The medical and surgical data were noted: age, parity, history of comorbidity, number and type of previous surgeries, body mass index (BMI), operating time, the requirement of intraoperative conversion, the presence of intra- or postoperative complication, estimated blood loss, pre-and postoperative hemoglobin levels, visual analog scale (VAS) pain scores at 6th, 12th and 24th hours, length of hospital stay, and the final pathology results.Results: vNOTES surgery was performed safely and successfully in eleven patients. There were no intra- and postoperative complications or instances of conversions to conventional laparoscopy or laparotomy. The mean age of patients was 75.91 ± 6.47 (range 70-93), and the mean BMI was 42.49 ± 8.77 kg/m2 (range 30.2-56). Seven cases of endometrioid adenocarcinoma, two cases of uterine leiomyoma, one case of complex atypical hyperplasia, and one case of postmenopausal uterine bleeding due to atrophic endometrium were diagnosed. All endometrial carcinomas were early stage; no adjuvant therapy was needed.Conclusions: vNOTES seems to be a safe and feasible approach for the treatment of gynecologic pathologies in elderly patients. This study suggests that vNOTES become a viable treatment option for existing minimally invasive procedures since it offers better surgical outcomes in various gynecologic surgeries.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49695364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of mRNA COVID-19 vaccine on ovarian reserve of women of reproductive age. mRNA新冠肺炎疫苗对育龄妇女卵巢储备的影响。

Ginekologia polska Pub Date : 2023-10-20 DOI: 10.5603/gpl.94997

Serkan Kumbasar, Suleyman Salman, Gizem Nur Çakmak, Fatma Ketenci Gencer, Leal Selin Sicakyüz, Ayşe Nur Kumbasar

{"title":"Effect of mRNA COVID-19 vaccine on ovarian reserve of women of reproductive age.","authors":"Serkan Kumbasar, Suleyman Salman, Gizem Nur Çakmak, Fatma Ketenci Gencer, Leal Selin Sicakyüz, Ayşe Nur Kumbasar","doi":"10.5603/gpl.94997","DOIUrl":"https://doi.org/10.5603/gpl.94997","url":null,"abstract":"Objectives: To evaluate the effect of messenger ribonucleic acid (mRNA) vaccines developed for severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) on the ovarian reserve of women of reproductive age.Material and methods: This prospective study was conducted between July and December 2022 in a tertiary care hospital affiliated with a university. A total of 117 patients were included in the study. The patients were divided into two groups. The first group (n = 62) consisted of women of reproductive age who received two doses of Pfizer-BioNTech COVID-19 vaccine administered 21 days apart. The control group (n = 55) included women with the same demographic characteristics who did not plan to be vaccinated. Hormonal values and basal antral follicle count were compared between two groups.Results: The mean age of the study group was 26.3 ± 3.6 years, and the mean age of the control group was 25.4 ± 6.2 years (p = 0.332). In the vaccinated group, mean follicular stimulating hormone (FSH) on day 2 was 5.29 ± 2.28; luteinizing hormone (LH): 5.18 ± 1.3; E2: 46.43 ± 24.51; anti-Mullerian hormone (AMH): 4.17 ± 2.1; antral follicle count: 16.23 ± 8.04; right ovarian volume: 6.4 ± 1.7; left ovarian volume: 6.2 ± 2.1. FSH measured at D2 in the control group was 5.68 ± 1.89; LH: 5.22 ± 2.2; E2: 48.41 ± 27.12; AMH: 4.30 ± 1.74; number of antral follicles: 15.64 ± 9.04; right ovarian volume: 6.1 ± 1.8; left ovarian volume: 6.3 ± 1.4. There were no statistically significant differences for FSH, LH, E2, AMH, ovarian volume, and number of antral follicles on the second day of menstruation between the groups.Conclusions: According to the results of the present study, the mRNA SARS-CoV-2 vaccine does not affect the ovarian reserve of patients.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using the National Nosocomial Infections Surveillance risk index to determine risk factors associated with surgical site infections following gynecologic surgeries. 使用国家医院感染监测风险指数来确定妇科手术后与手术部位感染相关的风险因素。

Ginekologia polska Pub Date : 2023-10-20 DOI: 10.5603/gpl.95073

Dong Wang, Jinlin Wu, Jianjun Deng, Ming Luo, Jie Ruan, Zhan Yang

{"title":"Using the National Nosocomial Infections Surveillance risk index to determine risk factors associated with surgical site infections following gynecologic surgeries.","authors":"Dong Wang, Jinlin Wu, Jianjun Deng, Ming Luo, Jie Ruan, Zhan Yang","doi":"10.5603/gpl.95073","DOIUrl":"https://doi.org/10.5603/gpl.95073","url":null,"abstract":"Objectives: We used the National Nosocomial Infections Surveillance (NNIS) risk index to determine risk factors associated with surgical site infections (SSIs) following gynecologic surgeries.Material and methods: A retrospective study was conducted based on the medical records of 185 patients with SSIs, following gynecologic surgeries at a Grade A tertiary gynecologic and obstetric hospital in southwest China during September 2013-June 2021.Results: Suspected risk factors associated with SSIs were: length of hospital stay, age, whether the patient had cancer, whether the patient had chemotherapy or high-dose antibiotic therapy before surgery, duration of surgery, amount of blood loss, and whether a blood transfusion was done. It was found that SSIs were more likely to occur in cancer patients with an NNIS risk index score of 1 and in patients with preoperative chemotherapy and an NNIS risk index score of 2. Among the patients with an NNIS risk index score of 2, the older the patient, the higher incidence of SSIs.Conclusions: Gynecologic surgery teams should pay more attention to the independent risk factors associated with SSIs determined by the NNIS risk index score to prevent SSIs following gynecologic surgeries, thus ensuring patient safety.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social marketing in gynecological cancers prevention after the COVID-19 pandemic. 新冠肺炎大流行后妇科癌症预防的社会营销。

Ginekologia polska Pub Date : 2023-10-16 DOI: 10.5603/gpl.94264

Izabela Norek, Artur Prusaczyk, Szymon Piątek, Mariusz Bidziński, Aneta Nitsch-Osuch, Magdalena Bogdan

{"title":"Social marketing in gynecological cancers prevention after the COVID-19 pandemic.","authors":"Izabela Norek, Artur Prusaczyk, Szymon Piątek, Mariusz Bidziński, Aneta Nitsch-Osuch, Magdalena Bogdan","doi":"10.5603/gpl.94264","DOIUrl":"https://doi.org/10.5603/gpl.94264","url":null,"abstract":"Objectives: Assessment of the development and description of the characteristics of social marketing in Poland and the United States with regard to the prevention of gynecological cancers and achievements of these countries.Material and methods: Collective case study based on an analysis of five social campaigns in Poland and five social campaigns in the United States that were focused the gynecological cancers prevention.Results: In the United States, there are more materials available on social campaigns dedicated to the prevention of gynecological cancers, and there are more public organizations that are involved in health promotion activities than in Poland. As opposed to American campaigns, Polish social campaigns did not cover all types of gynecological cancer. The study revealed that Facebook is the most commonly used social media platform by the social campaign organizers.Conclusions: Social marketing tools still have not been fully implemented in the prevention of gynecological cancers either in Poland or in the United States. However, social marketing in the US seems to be more effective in gynecological cancers prevention than Poland.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Female sexual functioning during pregnancy. 女性在怀孕期间的性功能。

Ginekologia polska Pub Date : 2023-10-16 DOI: 10.5603/gpl.93464

Edyta Szymanska, Rafal Kisielewski

引用次数: 0

Incisional hernia after ovarian debulking surgery. 卵巢切除术后切口疝。

Ginekologia polska Pub Date : 2023-10-16 DOI: 10.5603/gpl.95485

Harika Yumru Celiksoy, Hamdullah Sozen, Muhterem Melis Canturk, Hatice Merve Baktiroglu, Yavuz Salihoglu, Samet Topuz

{"title":"Incisional hernia after ovarian debulking surgery.","authors":"Harika Yumru Celiksoy, Hamdullah Sozen, Muhterem Melis Canturk, Hatice Merve Baktiroglu, Yavuz Salihoglu, Samet Topuz","doi":"10.5603/gpl.95485","DOIUrl":"https://doi.org/10.5603/gpl.95485","url":null,"abstract":"Objectives: The purpose of our study was to explore the incidence and contributing variables of an incisional hernia after debulking surgery for advanced ovarian cancer.Material and methods: The imaging of patients who underwent debulking surgery with an extended vertical incision was re-evaluated for incisional hernias at one-year follow-up, and their medical records were reviewed. We performed univariate and multivariate analysis to find out the risk factors for an incisional hernia.Results: The overall annual incidence of incisional hernia was 26.7 percent (46 of 172). Univariate analysis revealed a statistically significant relationship between age, body mass index (BMI), and the length of the incision and the incidence of an incisional hernia. The only factor identified by multivariate analysis as being independently related with the development of an incisional hernia within a year of the operation was BMI (OR 1.12, 95% CI 1.01-1.25, p = 0.04).Conclusions: Incisional hernia rates were high after ovarian cancer surgeries, and BMI was the independent factor significantly linked to hernia formation. To reduce the high ratio of incisional hernia among these group of patients, preventative strategies should be researched and applied.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasonographic diagnosis of ovarian tumors through the deep convolutional neural network. 卵巢肿瘤的深层卷积神经网络超声诊断。

Ginekologia polska Pub Date : 2023-10-16 DOI: 10.5603/gpl.94956

Min Xi, Runan Zheng, Mingyue Wang, Xiu Shi, Chaomei Chen, Jun Qian, Xinxian Gu, Jinhua Zhou

{"title":"Ultrasonographic diagnosis of ovarian tumors through the deep convolutional neural network.","authors":"Min Xi, Runan Zheng, Mingyue Wang, Xiu Shi, Chaomei Chen, Jun Qian, Xinxian Gu, Jinhua Zhou","doi":"10.5603/gpl.94956","DOIUrl":"https://doi.org/10.5603/gpl.94956","url":null,"abstract":"Objectives: The objective of this study was to develop and validate an ovarian tumor ultrasonographic diagnostic model based on deep convolutional neural networks (DCNN) and compare its diagnostic performance with that of human experts.Material and methods: We collected 486 ultrasound images of 192 women with malignant ovarian tumors and 617 ultrasound images of 213 women with benign ovarian tumors, all confirmed by pathological examination. The image dataset was split into a training set and a validation set according to a 7:3 ratio. We selected 5 DCNNs to develop our model: MobileNet, Xception, Inception, ResNet and DenseNet. We compared the performance of the five models through the area under the curve (AUC), sensitivity, specificity, and accuracy. We then randomly selected 200 images from the validation set as the test set. We asked three expert radiologists to diagnose the images to compare the performance of radiologists and the DCNN model.Results: In the validation set, AUC of DenseNet was 0.997 while AUC was 0.988 of ResNet, 0.987 of Inception, 0.968 of Xception and 0.836 of MobileNet. In the test set, the accuracy was 0.975 with the DenseNet model versus 0.825 (p < 0.0001) with the radiologists, and sensitivity was 0.975 versus 0.700 (p < 0.0001), and specificity was 0.975 versus 0.908 (p < 0.001).Conclusions: DensNet performed better than other DCNNs and expert radiologists in identifying malignant ovarian tumors from benign ovarian tumors based on ultrasound images, a finding that needs to be further explored in clinical trials.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0