Jakub Staniczek, Maisa Manasar-Dyrbus, Rafal Stojko, Aleksandra Matonog, Katarzyna Wilk-Sikora, Maja Zieba-Domalik, Jonasz Troszka, Szymon Stojko, Agnieszka Drosdzol-Cop
{"title":"Obstetric and neonatal risks of Streptococcus agalactiae in adolescent pregnancy: a retrospective matched cohort study.","authors":"Jakub Staniczek, Maisa Manasar-Dyrbus, Rafal Stojko, Aleksandra Matonog, Katarzyna Wilk-Sikora, Maja Zieba-Domalik, Jonasz Troszka, Szymon Stojko, Agnieszka Drosdzol-Cop","doi":"10.5603/gpl.105549","DOIUrl":"https://doi.org/10.5603/gpl.105549","url":null,"abstract":"<p><strong>Objectives: </strong>Streptococcus agalactiae (GBS) infection is significant in obstetric and neonatal complications. Maternal age, particularly adolescent pregnancy, may influence the prevalence of GBS colonization and associated clinical outcomes. This study aimed to evaluate the impact of maternal age on obstetric and neonatal outcomes, with a specific focus on the modifying effect of GBS status. The analysis explored whether the associations between maternal age and selected outcomes remained statistically significant after adjusting for GBS interactions.</p><p><strong>Material and methods: </strong>A retrospective matched cohort study was conducted with 582 participants, comprising a study group and a matched control group selected through propensity score matching. The study group included adolescents (≤ 19 years, n = 194) and older individuals (> 19 years, n = 388). Inclusion criteria required GBS screening after the 35th week of gestation, bacterial culture upon hospital admission, and delivery during the same hospitalization. Statistical analyses included logistic and linear regression models adjusted for interactions with GBS.</p><p><strong>Results: </strong>In unadjusted analyses, adolescent mothers showed a higher likelihood of postpartum hemorrhage (OR = 2.715, p = 0.02), uterine atony (OR = 3.594, p = 0.043), transient tachypnea of the newborn (TTN) (OR = 6.16, p = 0.027), and shorter neonatal length (Estimation = -0.791, p = 0.001). However, after adjusting for interactions with GBS, these associations lost statistical significance: postpartum hemorrhage (AOR = 0.67, p = 0.711), uterine atony (AOR = 2.417, p = 0.315), TTN (AOR = 4.87, p = 0.117), and neonatal length (Estimation = -0.207, p = 0.584).</p><p><strong>Conclusions: </strong>These findings indicate that GBS colonization confounds the observed relationships between maternal age and these outcomes. These results underscore the importance of accounting for GBS status in assessing age-related risks during pregnancy and tailoring clinical management accordingly.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The challenge of Mevalonate Kinase Deficiency as one of the causes of nonimmune hydrops fetalis.","authors":"Aleksandra Mikolajczak, Katarzyna Bernat-Sitarz","doi":"10.5603/gpl.104678","DOIUrl":"https://doi.org/10.5603/gpl.104678","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Faruk Olcenoglu, Merve Olcenoglu, Mesut Onal, Ayse Zehra Ozdemir
{"title":"Hysteroscopic isthmocele resection: evaluating quality of life and symptom improvements based on isthmocele volume.","authors":"Mehmet Faruk Olcenoglu, Merve Olcenoglu, Mesut Onal, Ayse Zehra Ozdemir","doi":"10.5603/gpl.102045","DOIUrl":"https://doi.org/10.5603/gpl.102045","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate grade 3 isthmocele resection performed via hysteroscopy and the impact of isthmocele size on symptoms caused by isthmocele and quality of life.</p><p><strong>Material and methods: </strong>This retrospective study included patients with grade 3 isthmocele who underwent hysteroscopy between January 2014 and June 2022. Age, body mass index, obstetric & gynecologic characteristics, operation duration, complications, and pre- and postoperative hemoglobin levels were recorded. Quality of life was assessed using the 36-Item Short Form Survey (SF-36). Patients were divided into two groups based on isthmocele volume: < 36 mm² and ≥ 36 mm².</p><p><strong>Results: </strong>A total of 47 women with a mean age of 36.6 ± 4.7 were included in the study. Twenty-two (46.81%) had an isthmocele size of < 36 mm² while 25 (53.19%) were in the ≥ 36 mm² group. There were no significant differences between the groups in terms of demographic and surgical characteristics, and there were no complications. Both groups demonstrated significant improvements in menstrual bleeding length, severity of postmenstrual spotting, frequency of postcoital bleeding, dyspareunia and dysmenorrhea, analgesic use, and quality of life. Compared to the < 36 mm² group, the ≥ 36 mm² group had significantly higher frequency of preoperative analgesic use (p = 0.041), better postoperative quality of life (p = 0.031), and greater improvement in quality of life (p = 0.028).</p><p><strong>Conclusions: </strong>Hysteroscopic isthmocele resection is an effective and safe method for treating isthmocele and achieves considerable improvements in symptoms and quality of life. Patients with larger isthmoceles experience greater improvements in several parameters, suggesting the inclusion of isthmocele volume in treatment decisions.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michal Ciebiera, Monika Baczkowska, Artur Skowyra, Krystyna Swiderska, Kornelia Zareba
{"title":"Pelvic inflammatory disease accompanied by necrosis and pyomyoma as a complication of intrauterine insemination - a case report.","authors":"Michal Ciebiera, Monika Baczkowska, Artur Skowyra, Krystyna Swiderska, Kornelia Zareba","doi":"10.5603/gpl.93173","DOIUrl":"https://doi.org/10.5603/gpl.93173","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maisa Manasar-Dyrbus, Bohdan Seifert, Agnieszka Drosdzol-Cop, Rafal Stojko, Jakub Staniczek
{"title":"Transforming clinical practice in just one year: lessons from external cephalic version success.","authors":"Maisa Manasar-Dyrbus, Bohdan Seifert, Agnieszka Drosdzol-Cop, Rafal Stojko, Jakub Staniczek","doi":"10.5603/gpl.105728","DOIUrl":"https://doi.org/10.5603/gpl.105728","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the safety and feasibility of implementing an external cephalic version (ECV) with routinely offered regional anesthesia and its impact on the cesarean section (CS) rate at a single large center in Poland.</p><p><strong>Material and methods: </strong>A retrospective analysis was conducted on 110 pregnant women with non-cephalic fetal presentations who were offered an ECV procedure at term between October 2023 and November 2024. Patients were offered regional anesthesia regularly. The endpoints studied were the success rates of ECV, pain levels in the VAS (Visual Analogue Scale) score and subsequent delivery methods. A univariable regression model was employed to identify factors influencing ECV success.</p><p><strong>Results: </strong>Of the 110 pregnant patients fulfilling the criteria for ECV, 56 underwent a total of 61 ECV attempts. Of those, 39 attempts (63.9%) were successful, resulting in 30 vaginal deliveries. Once administered, regional anesthesia significantly reduced procedural pain (VAS 3 [2-4] vs 0 [0-1] points, p < 0.001). A logistic regression model identified maternal BMI as a significant factor influencing ECV success (OR = 1.257, p = 0.018). Of the 61 attempts of ECV, two resulted in urgent cesarean section. ECV implementation resulted in a 2.12% reduction in the overall CS rate at the institution. Further reductions-up to nearly 4% - could be achieved if all eligible patients consented to the procedure.</p><p><strong>Conclusions: </strong>This study demonstrates that ECV, especially with regional anesthesia, is a feasible and effective strategy for reducing cesarean section rates and can be easily implemented into routine clinical practice. Widespread adoption of ECV could significantly decrease CS rates, improving perinatal care in Poland.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mateusz M Klimek, Agnieszka Skorupa, Mateusz Ciszek, Tomasz Cichon, Bartosz Cichon, Lukasz Boguszewicz, Andrzej Witek, Maria Sokol
{"title":"NMR-based serum metabolomics in patients with low-differentiated serous ovarian cancer.","authors":"Mateusz M Klimek, Agnieszka Skorupa, Mateusz Ciszek, Tomasz Cichon, Bartosz Cichon, Lukasz Boguszewicz, Andrzej Witek, Maria Sokol","doi":"10.5603/gpl.101741","DOIUrl":"https://doi.org/10.5603/gpl.101741","url":null,"abstract":"<p><strong>Objectives: </strong>In this pilot study the proton Nuclear Magnetic Resonance (¹H NMR)-based metabolomics was applied to explore the serum metabolomes of the patients with high-grade serous ovarian carcinoma (HGSOC) and the patients with benign gynaecological disease and to identify the characteristic biomarkers.</p><p><strong>Material and methods: </strong>We analyzed serum samples from 17 HGSOC patients and 14 control patients with benign gynecological conditions. Serum metabolites were profiled using 1H NMR spectroscopy, and multivariate data analyses, including Orthogonal Partial Least Squares Discriminant Analysis (OPLS-DA), were performed to identify discriminating metabolites.</p><p><strong>Results: </strong>The multivariate analysis revealed the lower levels of the lipid compounds, choline, branched-chain amino acids, 3-hydroxybutyrate (3HB), acetoacetate, and the higher level of lactate in the sera of the HGSOC patients compared to the control group.</p><p><strong>Conclusions: </strong>NMR-based metabolomic analysis can serve as a supporting method for the detection of ovarian cancer and may be useful as an adjunct to molecular diagnostics.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of USG-MRI and post-natal results of Cases with anomalies detected in fetal CNS examination.","authors":"Zafer Bütün, Masum Kayapınar, Gökalp Şenol","doi":"10.5603/gpl.101730","DOIUrl":"https://doi.org/10.5603/gpl.101730","url":null,"abstract":"<p><strong>Objectives: </strong>Magnetic resonance imaging (MRI) imaging can be useful when fetal central nervous system (CNS) anomalies are detected by ultrasound (USG). This study aims to compare the findings from USG and MRI with post-natal results in cases of fetal CNS anomalies.</p><p><strong>Material and: </strong>METHODS: This is a retrospective/prospective study that analyzed the records of 55 pregnant women who underwent both fetal MRI and USG and whose birth results were obtained due to suspected CNS abnormalities between 2020 and 2023.</p><p><strong>Results: </strong>Pearson correlation analysis and Blant-Altman analysis showed that USG and MRI results of right lateral ventricle measurement were more similar compared to left lateral ventricle measurement. When the cut-off value for lateral ventricle measurement was 10 mm, there was a difference in the USG and MRI results of only 1 pregnant woman in the right lateral ventricle USG-MRI comparison, whereas no difference was observed in 9 pregnant women in the left lateral ventricle analysis. One pregnant woman with healthy USG results was found to have corpus callosum hypoplasia by MRI and one pregnant woman with posterior fossa anomaly by USG had healthy MRI results. All other measurements showed similar results between USG and MRI.</p><p><strong>Conclusions: </strong>Fetal MRI, when performed with appropriate indications in selected cases evaluated by USG, is useful for measuring the lateral ventricles and detecting various CNS anomalies. The advancing technology of USG and MRI devices, along with the experience of the physicians interpreting these examinations, will always be important.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katarzyna A Urbańska, Beata M Naworska, Karolina Bednarz, Szymon Stojko, Agnieszka B Drosdzol-Cop
{"title":"Life satisfaction and self-efficacy of nurses and midwives in caring for newborns with lethal anomalies.","authors":"Katarzyna A Urbańska, Beata M Naworska, Karolina Bednarz, Szymon Stojko, Agnieszka B Drosdzol-Cop","doi":"10.5603/gpl.104634","DOIUrl":"https://doi.org/10.5603/gpl.104634","url":null,"abstract":"<p><strong>Objectives: </strong>The nursing and midwifery professions are potential influences on life satisfaction and self-efficacy, especially in obstetric settings dealing with fetal demise or severe congenital anomalies. This study aimed to assess how sociodemographic factors (e.g., workplace, marital status, financial situation, occupation, and tenure) and specific job exposures (frequency of neonatal death and caregiving for newborns with lethal defects) impact life satisfaction and self-efficacy among nurses and midwives. The study further explored the role of employer-provided psychological support in influencing job satisfaction and self-efficacy.</p><p><strong>Material and methods: </strong>A diagnostic survey with a custom questionnaire, supplemented by the General Self-Efficacy Life satisfaction and self-efficacy (GSES) and Satisfaction with Life Scale (SWLS), was conducted in level II and III referral centers in Poland's Silesian region in 2023. Participants included nurses and midwives in various neonatal and obstetric departments. Statistical analyses encompassed descriptive statistics, chi-square tests, and Spearman correlations, with significance set at p < 0.05.</p><p><strong>Results: </strong>A majority of participants reported moderate to high life satisfaction (41.7%) and self-efficacy (59.0%). Key factors impacting life satisfaction included marital status, financial situation, education, tenure, and caregiving frequency for newborns with lethal defects. High self-efficacy was significantly associated with job satisfaction, tenure, and workplace environment but was unaffected by marital status, financial situation, or psychological support.</p><p><strong>Conclusions: </strong>The findings highlight the emotional burden on nurses and midwives in neonatal care. Enhanced psychological support, stress-coping training, and policy adjustments are recommended to support this workforce. Further studies should broaden regional scope and examine links between life satisfaction, self-efficacy, and job satisfaction.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanna Dancewicz, Anita Kwiatkowska, Joanna Gebarowska, Carlo Bienkowski, Maria Pokorska-Spiewak
{"title":"The attitudes of pregnant or breastfeeding polish women towards COVID-19 vaccinations: a cross-sectional survey study.","authors":"Hanna Dancewicz, Anita Kwiatkowska, Joanna Gebarowska, Carlo Bienkowski, Maria Pokorska-Spiewak","doi":"10.5603/gpl.103797","DOIUrl":"https://doi.org/10.5603/gpl.103797","url":null,"abstract":"<p><strong>Objectives: </strong>Pregnant women are at higher risk of severe course of COVID-19. The vaccination against COVID-19 is recommended in pregnant and breastfeeding women. The aim of the study was to assess the attitude towards vaccination against COVID-19 among Polish pregnant or breastfeeding women.</p><p><strong>Material and methods: </strong>A cross-sectional survey study was performed from April 20th, 2021, to October 23rd, 2021, using an online questionnaire distributed via social media. Women who weren't Polish or didn't live in Poland were excluded from the study.</p><p><strong>Results: </strong>The study group consisted of 662 women. Their median age was 32.5 years (interquartile range IQR: 27.25-33.75 years). Most of the women lived in acity with over 500000 inhabitants (333/662, 50.30%), were in a relationship (658/662, 99.40%), had higher education (559/662, 84.44%), were currently employed (326/662, 49.25%), but not in a medical field (574/662, 86.71%). Willingness to be vaccinated was expressed in 231/662 (34.89%) of the surveyed women. A positive attitude towards vaccinations was more common among women working in the medical field (p = 0.006679), with higher education (p = 0.000054), who trusted their doctors (p = 0.003900), thought that vaccines against COVID-19 were effective (p < 0.00001), and those afraid of COVID-19 (p < 0.00001).</p><p><strong>Conclusions: </strong>The study showed that only one third of the surveyed women wanted to be vaccinated against COVID-19. Women working in the medical field, with higher education, who trusted their doctors, thought that vaccines against COVID-19 were effective, and those afraid of COVID-19 were more prone to be vaccinated against COVID-19 with recommended vaccines. Educational role of healthcare workers might be crucial for increasing the COVID-19 vaccine coverage in pregnant and breastfeeding women.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}