Ginekologia polska最新文献_第9页

Abdominal pain turned out to be OHVIRA syndrome. 腹痛原来是OHVIRA综合征。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-04-14 DOI: 10.5603/gpl.96363

Marta Zalewska-Zacharek, Wojciech Pawlak, Agnieszka Kolossa, Agnieszka Szykanowska, Michalina Gruszczynska

引用次数: 0

The role of the Systemic Inflammatory Response Index (SIRI) and other maternal biochemical markers in determining the severity of intrahepatic cholestasis of pregnancy. 系统性炎症反应指数（SIRI）及其他母体生化指标在确定妊娠肝内胆汁淤积严重程度中的作用。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.5603/gpl.102459

Derya Kanza Gul, Nihal Callioglu

{"title":"The role of the Systemic Inflammatory Response Index (SIRI) and other maternal biochemical markers in determining the severity of intrahepatic cholestasis of pregnancy.","authors":"Derya Kanza Gul, Nihal Callioglu","doi":"10.5603/gpl.102459","DOIUrl":"10.5603/gpl.102459","url":null,"abstract":"Objectives: To investigate the roles of the systemic inflammatory response index (SIRI) and other biochemical markers obtained from maternal blood in determining the diagnosis and severity of pregnancy cholestasis.Material and methods: In this retrospective case-control study, a total of 815 pregnant women including 546 healthy pregnant women [serum total bile acid (TBA) level < 10 μmol/L, control group], 185 patients with mild cholestasis [serum TBA level < 40 μmol/L, mild intrahepatic cholestasis of pregnancy (ICP) group] and 84 patients with severe cholestasis (serum TBA level ≥ 40 μmol/L, severe ICP group) were evaluated. The groups were compared regarding demographic data, clinical characteristics, SIRI (neutrophilcount*monocytecount/lymphocyte count), and other laboratory data. Cut-off values that could predict ICP were calculated.Results: The average neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), and systemic inflammatory response index (SIRI) were found to be statistically significantly higher in the severe ICP group compared with the control group and mild ICP group (p < 0.01 and p < 0.05). The best SIRI cut-off value was 2.3302 (60.3% sensitivity and 52.2% specificity) [area under the curve: 0.590 ± 0.023, 95% confidence interval (CI): 0.546-0.634; p < 0.001].Conclusions: SIRI may be a useful marker in determining the diagnosis and severity of ICP. However, were commend that studies be conducted in larger groups and indifferent trimesters.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"379-384"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is there a relationship between genital hiatus distance and the presence of pelvic organ prolapse? 生殖器裂孔距离与盆腔器官脱垂是否有关系？

IF 1

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-05-26 DOI: 10.5603/gpl.104178

Erdinç Dinçer, Fatih Tarhan

{"title":"Is there a relationship between genital hiatus distance and the presence of pelvic organ prolapse?","authors":"Erdinç Dinçer, Fatih Tarhan","doi":"10.5603/gpl.104178","DOIUrl":"10.5603/gpl.104178","url":null,"abstract":"Objectives: Pelvic organ prolapse (POP) is an important disease affecting the quality of life of women. We aimed to investigate the relationship of genital hiatus (GH) and anogenital distance (AGD) measurements with POP in patients with lower urinary tract symptoms.Material and methods: 1696 Patients who underwent urodynamic investigations in our clinics were evaluated retrospectively. Demographic data, physical examination data and urodynamic investigation results of all patients were evaluated. Those beyond POPQ stage 2 and above were considered to have pelvic organ prolapse.Results: The mean age was 49.44 ± 0.27 years, and the mean body-mass index was 30.08 ± 0.16 kg/m². While 682 patients (40.2%) were considered as having no POP, 1014 patients (59.8%) were considered as having POP. A statistically significant difference was found between the groups in terms of POP status respect of the parity, mean GH and AGD, and hysterectomy rate (p < 0.05). Mean GH, PB and AGD were significantly different among POP stage groups. (p < 0.05). In the correlation analysis, there was a positive correlation between POP stage parity (p = 0.0003, r = 0.059), GH (p < 0.0001, r = 0.353) and AGD (p < 0.0001, r = 0.299). The logistic regression revealed that genital hiatus distance and hysterectomy were statistically significant factors associated with POP. In ROC analysis, when the GH distance measurement is > 2.5 cm, the probability of POP status was found with sensitivity of 77.4% and specificity of 53.2% (p < 0.001).Conclusions: GH measurement can be marker for POP in a population of women being evaluated for urinary incontinence. GH measurement > 2.5 cm may associated with POP status.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"723-727"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of gestational diabetes mellitus with different birth weight on genetic metabolism of newborns. A retrospective cohort study. 不同出生体重的妊娠糖尿病对新生儿遗传代谢的影响。回顾性队列研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-03-12 DOI: 10.5603/gpl.102641

Dandan Xia, Huiyan Wang, Yuqi Yang, Wenli Wang

{"title":"Effects of gestational diabetes mellitus with different birth weight on genetic metabolism of newborns. A retrospective cohort study.","authors":"Dandan Xia, Huiyan Wang, Yuqi Yang, Wenli Wang","doi":"10.5603/gpl.102641","DOIUrl":"10.5603/gpl.102641","url":null,"abstract":"Objectives: To investigate the effects of gestational diabetes mellitus (GDM) with different birth weights on neonatal genetic metabolism.Material and methods: 1252 patients with GDM diagnosed at Changzhou Maternal and Child Health Care Hospital from 2017 to 2021 were categorized into three groups: fetal growth restriction (G1), normal birth weight (G2), and macrosomia (G3). The levels of amino acids, free carnitine (CO) and acylcarnitine in neonates were detected using tandem mass spectrometry.Results: There were no differences in age, height, predelivery weight or gravida across groups. G3 had the highest parity and fasting blood glucose levels (p < 0.0001). G1 exhibited the highest rates of cesarean section, neonatal asphyxia, and insulin utilization (p < 0.0001). Neonatal genetic metabolism analysis revealed that in G1 citrulline levels were the highest, with significantly elevated levels of leucineornithine and valine (p < 0.001). CO was also the highest (p < 0.001). The levels of isovalerylcarnitine, octanoylcarnitine and 18-carbodienoylcarnitine increased, while malonylcarnitine/3-hydroxy-butyrylcarnitine, hexadecanoylcarnitine, hexadecenoylcarnitine, 3-hydroxy-hexadecenoylcarnitine and 3-hydroxy-hexadecanoylcarnitine decreased (p < 0.05). In G2, methionine levels decreased (p < 0.001), whereas decenoylcarnitine, dodecanoylcarnitine, dodecenoylcarnitine and myristoylcarnitine levels increased (p < 0.001). In G3, proline decreased significantly (p < 0.001), and CO was the lowest (p < 0.001). Propionylcarnitine and octenoylcarnitine levels increased, whereas butyrylcarnitine decreased (p < 0.05).Conclusions: Gestational diabetes mellitus with different birth weights influences neonatal genetic metabolism in distinct ways. Therefore, neonatal screening for inherited metabolic disorders provides insights into the metabolic levels of offspring of patients with GDM in early life.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"469-475"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neoadjuvant chemotherapy in patients with vulvar carcinoma: a systematic review. 外阴癌患者的新辅助化疗：系统综述。

IF 1

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-02-18 DOI: 10.5603/gpl.97789

Magda Piechowicz, Wojciech Staskiewicz, Joanna Spaczyska, Milosz Pietrus, Kazimierz Pitynski

引用次数: 0

The role of Anti-Müllerian hormone in women health. 抗<s:1>勒氏杆菌激素在女性健康中的作用。

IF 1

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-01-29 DOI: 10.5603/gpl.96393

Aneta Czerwonogrodzka-Senczyna, Iwona Boniecka, Jakub Krawczyk, Anna Jeznach-Steinhagen

{"title":"The role of Anti-Müllerian hormone in women health.","authors":"Aneta Czerwonogrodzka-Senczyna, Iwona Boniecka, Jakub Krawczyk, Anna Jeznach-Steinhagen","doi":"10.5603/gpl.96393","DOIUrl":"10.5603/gpl.96393","url":null,"abstract":"Anti-Müllerian hormone (AMH), also known as Müller duct inhibitory factor and primarily known for its role in sexual differentiation. In female fetuses, AMH production by granulosa cells begins around the 36th week of gestation and continues in women until menopause. It is becoming more significant in the endocrine and gynecological diagnosis of adult women. The suppressive effect of AMH on follicle-stimulating hormone (FSH)-induced aromatase production likely plays a role in hyperandrogenism in polycystic ovary syndrome (PCOS) and may increase insulin resistance. Female adolescent with type 1 diabetes (T1D) have an increased likelihood of developing PCOS, but it is not known whether they also show elevated AMH levels. The elevated AMH levels observed in prepubertal girls with T1D suggest that there are more small follicles in their ovaries, probably in response to insulin treatment. Elevated levels of androgens and anti-Müllerian hormone have been previously reported in non-pregnant women with diabetes. The increased AMH concentrations can be associated with reduced systemic inflammation [lower c-reactive protein (CRP) values], irrespective of the type of diet and greater insulin sensitivity in old obese males. AMH can also serve as a valuable marker for granulosa cell tumors (folliculomas) and their recurrence. In these clinical scenarios, AMH levels can be significantly elevated and correspond with the size of the tumor.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"781-786"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of body mass index and gestational weight gain on cesarean delivery rates: a comparative study of dinoprostone-induced vs spontaneous labor. 体重指数和妊娠体重增加对剖宫产率的影响：地诺前列酮诱导分娩与自然分娩的比较研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.5603/gpl.100230

Andrzej Jaworowski, Agnieszka Micek, Magdalena Kolak, Katarzyna Skibinska-Frankowska, Julia Jurga, Kuba Ptaszkiewicz, Hubert Huras

{"title":"Impact of body mass index and gestational weight gain on cesarean delivery rates: a comparative study of dinoprostone-induced vs spontaneous labor.","authors":"Andrzej Jaworowski, Agnieszka Micek, Magdalena Kolak, Katarzyna Skibinska-Frankowska, Julia Jurga, Kuba Ptaszkiewicz, Hubert Huras","doi":"10.5603/gpl.100230","DOIUrl":"10.5603/gpl.100230","url":null,"abstract":"Objectives: This study investigates the relationship between pre-pregnancy body mass index (BMI), BMI before labor, and weight gain during pregnancy with the incidence of cesarean delivery (CD) in dinoprostone-induced labor versus spontaneous labor.Material and methods: This retrospective analysis was carried out at the Jagiellonian University Hospital's Obstetrics and Perinatology Department, encompassing term singleton pregnancies from May 2019 to February 2021. BMI was categorized following WHO guidelines. Gestational weight gain was assessed against the Institute of Medicine's 2009 recommendations.Results: Of the 366 cases reviewed, 183 were in the dinoprostone-induced labor group, and 183 were in the spontaneous labor group. The study identified a significant association between higher pre-pregnancy BMI and increased weight gain during pregnancy with elevated CD rates, especially in dinoprostone-induced labor compared to spontaneous labor. Specifically, the dinoprostone-induced labor group showed a 33.9% CD rate compared to 16.9% in the spontaneous labor group. Logistic regression analysis further established that for each 1 kg/m² increase in pre-pregnancy BMI, the odds of undergoing a CD increased by 10%.Conclusions: Elevated pre-pregnancy BMI and excessive gestational weight gain significantly heighten the risk of cesarean delivery, particularly in induced labor. The findings underline the need for individualized labor management strategies for women with higher BMI to optimize maternal and neonatal outcomes.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of VCare and SecuFix uterine manipulator in total laparoscopic hysterectomy: a prospective randomized trial. VCare和SecuFix子宫操纵器在腹腔镜全子宫切除术中的比较：一项前瞻性随机试验。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-02-11 DOI: 10.5603/gpl.101589

Emre Mat, Esra Keles, Pınar Yıldız, Murat Levent Dereli, Fatih Şanlıkan, Gazi Yıldız

{"title":"Comparison of VCare and SecuFix uterine manipulator in total laparoscopic hysterectomy: a prospective randomized trial.","authors":"Emre Mat, Esra Keles, Pınar Yıldız, Murat Levent Dereli, Fatih Şanlıkan, Gazi Yıldız","doi":"10.5603/gpl.101589","DOIUrl":"10.5603/gpl.101589","url":null,"abstract":"Objectives: To compare the Vcare and SecuFix uterine manipulators (UM) used in total laparoscopic hysterectomy (TLH) with regard to operating time, duration of hospital stay, the time for insertion of the manipulator, time for completion of colpotomy, and maintenance of pneumoperitoneum, estimated blood loss, and perioperative complications.Material and methods: This prospective, single-center, randomized controlled trial was conducted on patients who underwent TLH for benign indications between June 2023 and January 2024. Patients were randomized to either the Vcare UM or SecuFix UM group. Both groups were compared for operative time, colpotomy time, intrauterine manipulator insertion time, pneumoperitoneum maintenance, blood loss, complications, and length of hospital stay.Results: A total of 100 patients were enrolled, 50 with VcareUM and 50 with SecuFix UM. SecuFix UM demonstrated shorter colpotomy time (p < 0.001) and better pneumoperitoneum maintenance (p = 0.008) compared to VCare. VCare had shorter insertion time (p = 0.001) but a higher uterine rupture rate (p = 0.001). No significant differences were found in operative time, blood loss, complications, or length of hospital stay (p > 0.05).Conclusions: SecuFix may offer advantages in colpotomy and pneumoperitoneum maintenance during TLH compared to VCare. The Vcare UM demonstrated a shorter insertion time than the SecuFix UMs, yet a higher rate of uterine rupture was observed with its placement.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"168-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cystocele and rectocele repair with native tissue layers: definition of the technique. 用天然组织层修复囊突和直肠突：技术的定义。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.5603/gpl.100446

Ozan Dogan, Cagri Gulumser, Gokce Gokkaya, Murat Yassa

{"title":"Cystocele and rectocele repair with native tissue layers: definition of the technique.","authors":"Ozan Dogan, Cagri Gulumser, Gokce Gokkaya, Murat Yassa","doi":"10.5603/gpl.100446","DOIUrl":"10.5603/gpl.100446","url":null,"abstract":"Objectives: To investigate the outcomes of central cystocele and rectocele repair using natural tissue layers. To describe a novel technique (Dogan technique).Material and methods: This is a retrospective cohort study. Between January 2021 and January 2023, patients who had central cystocele and rectocele higher than stage1 were included in the study. The Pelvic Organ Prolapse Quantification (POP-Q) score was used to determine the degree of the prolapsus. All cystocele and rectocele repair surgeries were performed by the same physician. The patients' voiding habits were assessed using ICIQ-SF and OAB-V8. Sexual function results were assessed with FSFI questionnaire before and after the operation. Transperineal ultrasonography was performed to examine mobility of the anterior and posterior compartments.Results: Total of 36 patients were diagnosed with grade 2 and above central cystocele (19, 52%) and rectocele (n = 17, 48%). After the operation the anatomical cure of anterior and posterior compartments was achieved for all patients in the two-years follow-up. According to voiding habits before the surgery, there were symptoms of stress urinary incontinence (SUI),urge urinary incontinence (URGE), both SUI and URGE, and no incontinence at the patients; 7 (36.8%), 14 (73.7%), 5 (26.3%), 3 (15.7%) respectively. Of those URGE patients (n = 5/14, 35.7%) incontinence symptoms were mixed-type. After the cystocele operation, significant improvement was seen in their voiding problems according to the ICIQ-SF and OAB-V8 questionnaires (p < 0.05). As well as significant improvement was found in sexual function according to the FSFI questionnaire (p < 0.05).Conclusions: We showed that strengthening the anterior and/or posterior compartments with native tissue improves urge and voiding dysfunctions via a novel technique (Dogan technique) without removing the vagina tissue.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"13-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traditional vs novel out-of-office method for collecting cytology and HPV DNA - a comparative study. 传统与新型诊室外细胞学和人乳头瘤病毒 DNA 采集方法的比较研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.5603/gpl.100294

Marcin Januszewski, Laura M Ziuzia-Januszewska, Andrzej Durczynski, Jacek Holubka, Bogdan Siwek, Zofia Siwek, Zbigniew Derdziuk, Waldemar Wierzba, Artur J Jakimiuk

{"title":"Traditional vs novel out-of-office method for collecting cytology and HPV DNA - a comparative study.","authors":"Marcin Januszewski, Laura M Ziuzia-Januszewska, Andrzej Durczynski, Jacek Holubka, Bogdan Siwek, Zofia Siwek, Zbigniew Derdziuk, Waldemar Wierzba, Artur J Jakimiuk","doi":"10.5603/gpl.100294","DOIUrl":"10.5603/gpl.100294","url":null,"abstract":"Objectives: The integration of high-risk human papillomavirus (HPV) detection into cervical cancer screening in Poland aims to improve early detection, yet challenges in coverage and adherence persist. Innovative approaches, like sampling for HPV testing and cytology outside medical settings, have been proposed. This study assesses the feasibility and agreement of results between traditional and novel sampling methods.Material and methods: A cohort of 50 women aged 25-74 underwent HPV DNA and liquid-based cytology sampling both in-office using standard method and outside the medical setting by trained personnel. Samples were analyzed for HPV DNA using Real-Time PCR and cytology according to the Bethesda System.Results: Cytology and HPV DNA positivity rates showed substantial agreement between methods, with almost perfect agreement for high-risk HPV types. Visual assessment of the cervix was successfully conducted in all cases. Preliminary results suggest remote sampling for HPV DNA and cytology is a viable alternative to traditional methods, with the effectiveness in detecting HPV and cytological abnormalities comparable to this reported in literature, offering potential benefits for individuals with mobility limitations or logistical barriers to attending medical appointments.Conclusions: The study highlights the potential role of remote sampling for HPV DNA and cytology in enhancing cervical cancer screening accessibility and adherence. Implementation of such methods could improve coverage, particularly among underserved populations. Further research is needed to validate and optimize these approaches for broader clinical use.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"81-86"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0