Ginekologia polska最新文献_第9页

Strategies to reduce cesarean deliveries: surveying Polish obstetricians on external cephalic version practices. 减少剖宫产的策略：调查波兰产科医生的头外版本做法。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-11-29 DOI: 10.5603/gpl.102550

Maisa Manasar-Dyrbus, Agnieszka Drosdzol-Cop, Szymon Stojko, Rafal Stojko, Jakub Staniczek

{"title":"Strategies to reduce cesarean deliveries: surveying Polish obstetricians on external cephalic version practices.","authors":"Maisa Manasar-Dyrbus, Agnieszka Drosdzol-Cop, Szymon Stojko, Rafal Stojko, Jakub Staniczek","doi":"10.5603/gpl.102550","DOIUrl":"10.5603/gpl.102550","url":null,"abstract":"Objectives: The cross-sectional survey was conducted aiming to evaluate the knowledge and experiences of the Polish obstetricians and gynecologists regarding the External Cephalic Version (ECV) and investigate their practices concerning this procedure.Material and methods: An online survey constituting author-created questionnaire with 22 questions, was distributed among gynecologists and obstetricians. The questionnaire evaluated participants' knowledge about ECV, work experiences, and workplace practices.Results: Out of 461 respondents, 56.20% were specialists in gynecology and obstetrics. Elective cesarean section (CS) was preferred by 78.70% for primiparas and 73.50% for multiparas with non-cephalic presentation, while ECV would be chosen by 21.3% and 23.6%, respectively. While 73.80% knew centers performing ECV, only 16.70% had actively participated in the procedure. Major differences in the experiences and knowledge regarding ECV were observed based on work experience, and workplace reference level. Experienced physicians showed higher concerns about ECV complications and emergency CS risks. The most common concerns regarding the procedure referred to periprocedural pain, perceived low efficacy, and complications, and were more prevalent among respondents with longer experience and from lower-reference centers.Conclusions: The study demonstrated that among Polish obstetricians for term pregnancies with non-cephalic presentation, elective cesarean section is preferred over ECV, especially among experienced practitioners. Knowledge about ECV was relatively low, indicating a need for improved educational efforts. Addressing concerns about ECV's safety and efficacy, particularly through enhanced training and anesthesia options, could promote its adoption and reduce CS rates.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"271-281"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of the Systemic Inflammatory Response Index (SIRI) and other maternal biochemical markers in determining the severity of intrahepatic cholestasis of pregnancy. 系统性炎症反应指数（SIRI）及其他母体生化指标在确定妊娠肝内胆汁淤积严重程度中的作用。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.5603/gpl.102459

Derya Kanza Gul, Nihal Callioglu

{"title":"The role of the Systemic Inflammatory Response Index (SIRI) and other maternal biochemical markers in determining the severity of intrahepatic cholestasis of pregnancy.","authors":"Derya Kanza Gul, Nihal Callioglu","doi":"10.5603/gpl.102459","DOIUrl":"10.5603/gpl.102459","url":null,"abstract":"Objectives: To investigate the roles of the systemic inflammatory response index (SIRI) and other biochemical markers obtained from maternal blood in determining the diagnosis and severity of pregnancy cholestasis.Material and methods: In this retrospective case-control study, a total of 815 pregnant women including 546 healthy pregnant women [serum total bile acid (TBA) level < 10 μmol/L, control group], 185 patients with mild cholestasis [serum TBA level < 40 μmol/L, mild intrahepatic cholestasis of pregnancy (ICP) group] and 84 patients with severe cholestasis (serum TBA level ≥ 40 μmol/L, severe ICP group) were evaluated. The groups were compared regarding demographic data, clinical characteristics, SIRI (neutrophilcount*monocytecount/lymphocyte count), and other laboratory data. Cut-off values that could predict ICP were calculated.Results: The average neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), and systemic inflammatory response index (SIRI) were found to be statistically significantly higher in the severe ICP group compared with the control group and mild ICP group (p < 0.01 and p < 0.05). The best SIRI cut-off value was 2.3302 (60.3% sensitivity and 52.2% specificity) [area under the curve: 0.590 ± 0.023, 95% confidence interval (CI): 0.546-0.634; p < 0.001].Conclusions: SIRI may be a useful marker in determining the diagnosis and severity of ICP. However, were commend that studies be conducted in larger groups and indifferent trimesters.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"379-384"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of mismatch repair (MMR), p53, and LCAM-1 immunohistochemical expression on prognosis in low-risk endometrial cancer. 错配修复（MMR）、p53 和 LCAM-1 免疫组化表达对低危子宫内膜癌预后的影响。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-02-18 DOI: 10.5603/gpl.101983

Şener Gezer, Büşra Yaprak Bayrak, Müzeyyen Dilşad Eser, Esra Betül Tunce

{"title":"The impact of mismatch repair (MMR), p53, and LCAM-1 immunohistochemical expression on prognosis in low-risk endometrial cancer.","authors":"Şener Gezer, Büşra Yaprak Bayrak, Müzeyyen Dilşad Eser, Esra Betül Tunce","doi":"10.5603/gpl.101983","DOIUrl":"10.5603/gpl.101983","url":null,"abstract":"Objectives: To investigate the relationship between mismatch repair (MMR) deficiency, TP53, and L1 cell adhesion molecule (L1CAM) immunohistochemical staining and their impact on progression-free survival (PFS) and overall survival (OS) in low-risk endometrial cancer.Material and methods: A total of 253 low-risk endometrial cancer patients were retrospectively screened. Immunohistochemical stains were applied to tumor tissue samples to assess MMR deficiency, TP53, and L1CAM expression, and survival analysis were performed.Results: The expected PFS time was 78.6 months for the MMR-proficient group and 70.3 months for the MMR-deficient group (p = 0.011). OS was 71.6 months for the MMR-proficient group and 68.2 months for the MMR-deficient group (p = 0.755). L1CAM overexpression was associated with a poorer PFS, 62.7 months compared to 77.7 months (p = 0.039). However, there was no statistically significant difference in OS, 58.5 months versus 72.1 months, respectively (p = 0.242). p53 abnormal (p53-abn) staining was associated with a worse prognosis in terms of PFS, 62.8 months versus 77.7 months (p = 0.035), and OS, 43.4 months versus 73 months, respectively (p < 0.001), compared to patients with wild-type staining. No significant statistical relationship was observed in survival times concerning tumor diameter, grade, and lymphadenectomy status. In a multivariate analysis, MMR deficiency emerged as an independent poor prognostic factor for PFS, while p53-abn was identified as an independent poor prognostic factor for OS.Conclusions: p53-abn staining was associated with a poor prognosis for both PFS and OS in low-risk endometrial cancer patients. Meanwhile, MMR deficiency and L1CAM positivity were found to be associated solely with a poorer prognosis for PFS.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"446-453"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hysteroscopic isthmocele resection: evaluating quality of life and symptom improvements based on isthmocele volume. 宫腔镜峡部切除：评估生活质量和基于峡部体积的症状改善。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-05-12 DOI: 10.5603/gpl.102045

Mehmet Faruk Olcenoglu, Merve Olcenoglu, Mesut Onal, Ayse Zehra Ozdemir

{"title":"Hysteroscopic isthmocele resection: evaluating quality of life and symptom improvements based on isthmocele volume.","authors":"Mehmet Faruk Olcenoglu, Merve Olcenoglu, Mesut Onal, Ayse Zehra Ozdemir","doi":"10.5603/gpl.102045","DOIUrl":"10.5603/gpl.102045","url":null,"abstract":"Objectives: To investigate grade 3 isthmocele resection performed via hysteroscopy and the impact of isthmocele size on symptoms caused by isthmocele and quality of life.Material and methods: This retrospective study included patients with grade 3 isthmocele who underwent hysteroscopy between January 2014 and June 2022. Age, body mass index, obstetric & gynecologic characteristics, operation duration, complications, and pre- and postoperative hemoglobin levels were recorded. Quality of life was assessed using the 36-Item Short Form Survey (SF-36). Patients were divided into two groups based on isthmocele volume: < 36 mm² and ≥ 36 mm².Results: A total of 47 women with a mean age of 36.6 ± 4.7 were included in the study. Twenty-two (46.81%) had an isthmocele size of < 36 mm² while 25 (53.19%) were in the ≥ 36 mm² group. There were no significant differences between the groups in terms of demographic and surgical characteristics, and there were no complications. Both groups demonstrated significant improvements in menstrual bleeding length, severity of postmenstrual spotting, frequency of postcoital bleeding, dyspareunia and dysmenorrhea, analgesic use, and quality of life. Compared to the < 36 mm² group, the ≥ 36 mm² group had significantly higher frequency of preoperative analgesic use (p = 0.041), better postoperative quality of life (p = 0.031), and greater improvement in quality of life (p = 0.028).Conclusions: Hysteroscopic isthmocele resection is an effective and safe method for treating isthmocele and achieves considerable improvements in symptoms and quality of life. Patients with larger isthmoceles experience greater improvements in several parameters, suggesting the inclusion of isthmocele volume in treatment decisions.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"454-461"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abdominal pain turned out to be OHVIRA syndrome. 腹痛原来是OHVIRA综合征。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-04-14 DOI: 10.5603/gpl.96363

Marta Zalewska-Zacharek, Wojciech Pawlak, Agnieszka Kolossa, Agnieszka Szykanowska, Michalina Gruszczynska

引用次数: 0

Effects of gestational diabetes mellitus with different birth weight on genetic metabolism of newborns. A retrospective cohort study. 不同出生体重的妊娠糖尿病对新生儿遗传代谢的影响。回顾性队列研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-03-12 DOI: 10.5603/gpl.102641

Dandan Xia, Huiyan Wang, Yuqi Yang, Wenli Wang

{"title":"Effects of gestational diabetes mellitus with different birth weight on genetic metabolism of newborns. A retrospective cohort study.","authors":"Dandan Xia, Huiyan Wang, Yuqi Yang, Wenli Wang","doi":"10.5603/gpl.102641","DOIUrl":"10.5603/gpl.102641","url":null,"abstract":"Objectives: To investigate the effects of gestational diabetes mellitus (GDM) with different birth weights on neonatal genetic metabolism.Material and methods: 1252 patients with GDM diagnosed at Changzhou Maternal and Child Health Care Hospital from 2017 to 2021 were categorized into three groups: fetal growth restriction (G1), normal birth weight (G2), and macrosomia (G3). The levels of amino acids, free carnitine (CO) and acylcarnitine in neonates were detected using tandem mass spectrometry.Results: There were no differences in age, height, predelivery weight or gravida across groups. G3 had the highest parity and fasting blood glucose levels (p < 0.0001). G1 exhibited the highest rates of cesarean section, neonatal asphyxia, and insulin utilization (p < 0.0001). Neonatal genetic metabolism analysis revealed that in G1 citrulline levels were the highest, with significantly elevated levels of leucineornithine and valine (p < 0.001). CO was also the highest (p < 0.001). The levels of isovalerylcarnitine, octanoylcarnitine and 18-carbodienoylcarnitine increased, while malonylcarnitine/3-hydroxy-butyrylcarnitine, hexadecanoylcarnitine, hexadecenoylcarnitine, 3-hydroxy-hexadecenoylcarnitine and 3-hydroxy-hexadecanoylcarnitine decreased (p < 0.05). In G2, methionine levels decreased (p < 0.001), whereas decenoylcarnitine, dodecanoylcarnitine, dodecenoylcarnitine and myristoylcarnitine levels increased (p < 0.001). In G3, proline decreased significantly (p < 0.001), and CO was the lowest (p < 0.001). Propionylcarnitine and octenoylcarnitine levels increased, whereas butyrylcarnitine decreased (p < 0.05).Conclusions: Gestational diabetes mellitus with different birth weights influences neonatal genetic metabolism in distinct ways. Therefore, neonatal screening for inherited metabolic disorders provides insights into the metabolic levels of offspring of patients with GDM in early life.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"469-475"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of body mass index and gestational weight gain on cesarean delivery rates: a comparative study of dinoprostone-induced vs spontaneous labor. 体重指数和妊娠体重增加对剖宫产率的影响：地诺前列酮诱导分娩与自然分娩的比较研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.5603/gpl.100230

Andrzej Jaworowski, Agnieszka Micek, Magdalena Kolak, Katarzyna Skibinska-Frankowska, Julia Jurga, Kuba Ptaszkiewicz, Hubert Huras

{"title":"Impact of body mass index and gestational weight gain on cesarean delivery rates: a comparative study of dinoprostone-induced vs spontaneous labor.","authors":"Andrzej Jaworowski, Agnieszka Micek, Magdalena Kolak, Katarzyna Skibinska-Frankowska, Julia Jurga, Kuba Ptaszkiewicz, Hubert Huras","doi":"10.5603/gpl.100230","DOIUrl":"10.5603/gpl.100230","url":null,"abstract":"Objectives: This study investigates the relationship between pre-pregnancy body mass index (BMI), BMI before labor, and weight gain during pregnancy with the incidence of cesarean delivery (CD) in dinoprostone-induced labor versus spontaneous labor.Material and methods: This retrospective analysis was carried out at the Jagiellonian University Hospital's Obstetrics and Perinatology Department, encompassing term singleton pregnancies from May 2019 to February 2021. BMI was categorized following WHO guidelines. Gestational weight gain was assessed against the Institute of Medicine's 2009 recommendations.Results: Of the 366 cases reviewed, 183 were in the dinoprostone-induced labor group, and 183 were in the spontaneous labor group. The study identified a significant association between higher pre-pregnancy BMI and increased weight gain during pregnancy with elevated CD rates, especially in dinoprostone-induced labor compared to spontaneous labor. Specifically, the dinoprostone-induced labor group showed a 33.9% CD rate compared to 16.9% in the spontaneous labor group. Logistic regression analysis further established that for each 1 kg/m² increase in pre-pregnancy BMI, the odds of undergoing a CD increased by 10%.Conclusions: Elevated pre-pregnancy BMI and excessive gestational weight gain significantly heighten the risk of cesarean delivery, particularly in induced labor. The findings underline the need for individualized labor management strategies for women with higher BMI to optimize maternal and neonatal outcomes.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of VCare and SecuFix uterine manipulator in total laparoscopic hysterectomy: a prospective randomized trial. VCare和SecuFix子宫操纵器在腹腔镜全子宫切除术中的比较：一项前瞻性随机试验。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-02-11 DOI: 10.5603/gpl.101589

Emre Mat, Esra Keles, Pınar Yıldız, Murat Levent Dereli, Fatih Şanlıkan, Gazi Yıldız

{"title":"Comparison of VCare and SecuFix uterine manipulator in total laparoscopic hysterectomy: a prospective randomized trial.","authors":"Emre Mat, Esra Keles, Pınar Yıldız, Murat Levent Dereli, Fatih Şanlıkan, Gazi Yıldız","doi":"10.5603/gpl.101589","DOIUrl":"10.5603/gpl.101589","url":null,"abstract":"Objectives: To compare the Vcare and SecuFix uterine manipulators (UM) used in total laparoscopic hysterectomy (TLH) with regard to operating time, duration of hospital stay, the time for insertion of the manipulator, time for completion of colpotomy, and maintenance of pneumoperitoneum, estimated blood loss, and perioperative complications.Material and methods: This prospective, single-center, randomized controlled trial was conducted on patients who underwent TLH for benign indications between June 2023 and January 2024. Patients were randomized to either the Vcare UM or SecuFix UM group. Both groups were compared for operative time, colpotomy time, intrauterine manipulator insertion time, pneumoperitoneum maintenance, blood loss, complications, and length of hospital stay.Results: A total of 100 patients were enrolled, 50 with VcareUM and 50 with SecuFix UM. SecuFix UM demonstrated shorter colpotomy time (p < 0.001) and better pneumoperitoneum maintenance (p = 0.008) compared to VCare. VCare had shorter insertion time (p = 0.001) but a higher uterine rupture rate (p = 0.001). No significant differences were found in operative time, blood loss, complications, or length of hospital stay (p > 0.05).Conclusions: SecuFix may offer advantages in colpotomy and pneumoperitoneum maintenance during TLH compared to VCare. The Vcare UM demonstrated a shorter insertion time than the SecuFix UMs, yet a higher rate of uterine rupture was observed with its placement.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"168-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cystocele and rectocele repair with native tissue layers: definition of the technique. 用天然组织层修复囊突和直肠突：技术的定义。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.5603/gpl.100446

Ozan Dogan, Cagri Gulumser, Gokce Gokkaya, Murat Yassa

{"title":"Cystocele and rectocele repair with native tissue layers: definition of the technique.","authors":"Ozan Dogan, Cagri Gulumser, Gokce Gokkaya, Murat Yassa","doi":"10.5603/gpl.100446","DOIUrl":"10.5603/gpl.100446","url":null,"abstract":"Objectives: To investigate the outcomes of central cystocele and rectocele repair using natural tissue layers. To describe a novel technique (Dogan technique).Material and methods: This is a retrospective cohort study. Between January 2021 and January 2023, patients who had central cystocele and rectocele higher than stage1 were included in the study. The Pelvic Organ Prolapse Quantification (POP-Q) score was used to determine the degree of the prolapsus. All cystocele and rectocele repair surgeries were performed by the same physician. The patients' voiding habits were assessed using ICIQ-SF and OAB-V8. Sexual function results were assessed with FSFI questionnaire before and after the operation. Transperineal ultrasonography was performed to examine mobility of the anterior and posterior compartments.Results: Total of 36 patients were diagnosed with grade 2 and above central cystocele (19, 52%) and rectocele (n = 17, 48%). After the operation the anatomical cure of anterior and posterior compartments was achieved for all patients in the two-years follow-up. According to voiding habits before the surgery, there were symptoms of stress urinary incontinence (SUI),urge urinary incontinence (URGE), both SUI and URGE, and no incontinence at the patients; 7 (36.8%), 14 (73.7%), 5 (26.3%), 3 (15.7%) respectively. Of those URGE patients (n = 5/14, 35.7%) incontinence symptoms were mixed-type. After the cystocele operation, significant improvement was seen in their voiding problems according to the ICIQ-SF and OAB-V8 questionnaires (p < 0.05). As well as significant improvement was found in sexual function according to the FSFI questionnaire (p < 0.05).Conclusions: We showed that strengthening the anterior and/or posterior compartments with native tissue improves urge and voiding dysfunctions via a novel technique (Dogan technique) without removing the vagina tissue.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"13-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traditional vs novel out-of-office method for collecting cytology and HPV DNA - a comparative study. 传统与新型诊室外细胞学和人乳头瘤病毒 DNA 采集方法的比较研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.5603/gpl.100294

Marcin Januszewski, Laura M Ziuzia-Januszewska, Andrzej Durczynski, Jacek Holubka, Bogdan Siwek, Zofia Siwek, Zbigniew Derdziuk, Waldemar Wierzba, Artur J Jakimiuk

{"title":"Traditional vs novel out-of-office method for collecting cytology and HPV DNA - a comparative study.","authors":"Marcin Januszewski, Laura M Ziuzia-Januszewska, Andrzej Durczynski, Jacek Holubka, Bogdan Siwek, Zofia Siwek, Zbigniew Derdziuk, Waldemar Wierzba, Artur J Jakimiuk","doi":"10.5603/gpl.100294","DOIUrl":"10.5603/gpl.100294","url":null,"abstract":"Objectives: The integration of high-risk human papillomavirus (HPV) detection into cervical cancer screening in Poland aims to improve early detection, yet challenges in coverage and adherence persist. Innovative approaches, like sampling for HPV testing and cytology outside medical settings, have been proposed. This study assesses the feasibility and agreement of results between traditional and novel sampling methods.Material and methods: A cohort of 50 women aged 25-74 underwent HPV DNA and liquid-based cytology sampling both in-office using standard method and outside the medical setting by trained personnel. Samples were analyzed for HPV DNA using Real-Time PCR and cytology according to the Bethesda System.Results: Cytology and HPV DNA positivity rates showed substantial agreement between methods, with almost perfect agreement for high-risk HPV types. Visual assessment of the cervix was successfully conducted in all cases. Preliminary results suggest remote sampling for HPV DNA and cytology is a viable alternative to traditional methods, with the effectiveness in detecting HPV and cytological abnormalities comparable to this reported in literature, offering potential benefits for individuals with mobility limitations or logistical barriers to attending medical appointments.Conclusions: The study highlights the potential role of remote sampling for HPV DNA and cytology in enhancing cervical cancer screening accessibility and adherence. Implementation of such methods could improve coverage, particularly among underserved populations. Further research is needed to validate and optimize these approaches for broader clinical use.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"81-86"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0