Ginekologia polska最新文献_第5页

The role of the Systemic Inflammatory Response Index (SIRI) and other maternal biochemical markers in determining the severity of intrahepatic cholestasis of pregnancy. 系统性炎症反应指数（SIRI）及其他母体生化指标在确定妊娠肝内胆汁淤积严重程度中的作用。

Ginekologia polska Pub Date : 2025-01-15 DOI: 10.5603/gpl.102459

Derya Kanza Gul, Nihal Callioglu

{"title":"The role of the Systemic Inflammatory Response Index (SIRI) and other maternal biochemical markers in determining the severity of intrahepatic cholestasis of pregnancy.","authors":"Derya Kanza Gul, Nihal Callioglu","doi":"10.5603/gpl.102459","DOIUrl":"https://doi.org/10.5603/gpl.102459","url":null,"abstract":"Objectives: To investigate the roles of the systemic inflammatory response index (SIRI) and other biochemical markers obtained from maternal blood in determining the diagnosis and severity of pregnancy cholestasis.Material and methods: In this retrospective case-control study, a total of 815 pregnant women including 546 healthy pregnant women [serum total bile acid (TBA) level < 10 μmol/L, control group], 185 patients with mild cholestasis [serum TBA level < 40 μmol/L, mild intrahepatic cholestasis of pregnancy (ICP) group] and 84 patients with severe cholestasis (serum TBA level ≥ 40 μmol/L, severe ICP group) were evaluated. The groups were compared regarding demographic data, clinical characteristics, SIRI (neutrophilcount*monocytecount/lymphocyte count), and other laboratory data. Cut-off values that could predict ICP were calculated.Results: The average neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), and systemic inflammatory response index (SIRI) were found to be statistically significantly higher in the severe ICP group compared with the control group and mild ICP group (p < 0.01 and p < 0.05). The best SIRI cut-off value was 2.3302 (60.3% sensitivity and 52.2% specificity) [area under the curve: 0.590 ± 0.023, 95% confidence interval (CI): 0.546-0.634; p < 0.001].Conclusions: SIRI may be a useful marker in determining the diagnosis and severity of ICP. However, were commend that studies be conducted in larger groups and indifferent trimesters.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pelvic splenosis infiltrating the uterus and ovary. 盆腔脾肿大浸润子宫和卵巢。

Ginekologia polska Pub Date : 2025-01-15 DOI: 10.5603/gpl.103029

Monika Bekiesinska-Figatowska, Marta Dziuba, Krystyna Ignaciuk, Malgorzata Gajewska, Tomasz Sarosiek, Jaroslaw B Cwikla

引用次数: 0

The inflammatory breast cancer mimicker - the SMOLD syndrome - rare complication of smoking. 炎性乳腺癌模仿者- SMOLD综合征-吸烟的罕见并发症。

Ginekologia polska Pub Date : 2025-01-15 DOI: 10.5603/gpl.103103

Joanna Szczudlo-Chrascina, Pawel Bojar, Michal Holecki, Agnieszka Niewiadomska, Katarzyna Steinhof-Radwanska

引用次数: 0

Dysmenorrhea in OHVIRA syndrome. OHVIRA 综合征的痛经。

Ginekologia polska Pub Date : 2025-01-15 DOI: 10.5603/gpl.102953

Kinga Ksiezakowska-Lakoma, Malgorzata Soroka, Marek Brzezinski

引用次数: 0

Off-label letrozole for tubal pregnancy monotherapy is not an alternative to methotrexate: a prospective cohort study. 用于输卵管妊娠单药治疗的标签外来曲唑不能替代甲氨蝶呤：一项前瞻性队列研究。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.5603/gpl.100131

Iwona M Gawron, Dorota Babczyk, Robert Jach

{"title":"Off-label letrozole for tubal pregnancy monotherapy is not an alternative to methotrexate: a prospective cohort study.","authors":"Iwona M Gawron, Dorota Babczyk, Robert Jach","doi":"10.5603/gpl.100131","DOIUrl":"10.5603/gpl.100131","url":null,"abstract":"Objectives: Inhibition of estradiol production by letrozole may interfere with physiological effects of progesterone necessary to maintain the pregnancy. Treatment of tubal pregnancy (TP) with letrozole would allow to avoid the disadvantages of methotrexate (MTX). The aim was to compare the effectiveness of letrozole with MTX in the management of TP.Material and methods: A prospective open-label cohort study was conducted among women with TP and increasing B-human chorionic gonadotropin (B-hCG) concentrations. MTX was administered in a single dose of 100 mg intravenously, while letrozole in a dose of 5 mg orally for 10 days. Blood parameters (B-hCG, hemoglobin, creatinine, urea, transaminases, bilirubin) were tested on days 0, 4 and 7.Results: Out of 22 eligible women, 14 received MTX and received 8 letrozole. Mean age, lesion diameter, gestation age in the MTX vs letrozole arm were: 31 vs 32 years (p = 0.3), 13.2 vs 16.3 mm (p = 0.1), 7 + 1 vs 7 + 0 weeks (p = 0.6), respectively. In case of 4 women treated with letrozole and in 2 treated with MTX (4/8, 50% vs 2/14, 14.3%, p = 0.07) the treatment was unsuccessful. There were no significant differences in blood parameters on days 0, 4 and 7 between both arms, except for the increasing urea concentration in the letrozole arm (p = 0.01).Conclusions: Even though the results did not reach statistical significance, it is likely that a larger study sample would confirm the trend of letrozole being less effective. The results did not support the use of letrozole in the studied regimen as an alternative to MTX.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"51-57"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between MMP-9-C1562Tpolymorphism and susceptibility to preeclampsia: a systematic review and meta-analysis. MMP-9-C1562T多态性与先兆子痫易感性之间的关系：系统回顾和荟萃分析。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-10-16 DOI: 10.5603/gpl.100274

Ruihong Lan, Yang Yang, Jie Song, Hong Yang, Ling Wang, Humin Gong

{"title":"Association between MMP-9-C1562Tpolymorphism and susceptibility to preeclampsia: a systematic review and meta-analysis.","authors":"Ruihong Lan, Yang Yang, Jie Song, Hong Yang, Ling Wang, Humin Gong","doi":"10.5603/gpl.100274","DOIUrl":"10.5603/gpl.100274","url":null,"abstract":"Objectives: This meta-analysis aims to explore the association between MMP-9-C1562T polymorphism and susceptibility to preeclampsia (PE).Material and methods: Four English databases were searched to collect relevant records up to April 2024. The pooled odds ratio (OR) was calculated using Stata 15.0.Results: A total of 10 studies were enrolled in our systematic review. The results showed that genotype CT at MMP-9-C1562T locus increased the risk of PE versus genotype TT (Genotype CT vs TT: OR = 2.32, 95% CI: 1.27-4.24, P = 0.006), but no significant differences were found in other gene models (C vs T: OR = 0.88, 95% CI: 0.71-1.08, P = 0.225; Genotype CC vs TT: OR = 1.51, 95% CI: 0.87-2.61, P = 0.139; Genotype CC + CT vs TT: OR = 1.63, 95% CI: 0.95-2.81, P = 0.079; Genotype CC vs CT + TT: OR = 0.80, 95% CI: 0.63-1.03, P = 0.086). Subgroup analysis by ethnicity showed a statistically significant difference in the heterozygous model in China (Genotype CT vs TT: OR = 2.38, 95% CI: 1.15 -4.91, P = 0.019).Conclusions: Association of MMP-9-C1562T polymorphism with susceptibility to PE exists. Specifically, genotype CT increases the risk of PE versus genotype TT, particularly in Caucasian populations.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fetal cardiac function is altered by circumvallate placenta. 胎儿心功能被环瓣胎盘改变。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-11-29 DOI: 10.5603/gpl.101714

Oskar Sylwestrzak, Katarzyna Zych-Krekora, Lukasz Sokolowski, Maciej Ziebakowski, Michal Krekora

引用次数: 0

Initial paraneoplastic presentation of advanced choriocarcinoma. 晚期绒毛膜癌的初期副肿瘤性表现。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-08-14 DOI: 10.5603/gpl.100439

Julia Rudnicka, Aleksandra Urban, Julia Gorny, Anna Danska-Bidzinska, Ewa Romejko-Wolniewicz

引用次数: 0

Using the National Nosocomial Infections Surveillance risk index to determine risk factors associated with surgical site infections following gynecologic surgeries. 使用国家医院感染监测风险指数来确定妇科手术后与手术部位感染相关的风险因素。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2023-10-20 DOI: 10.5603/gpl.95073

Dong Wang, Jinlin Wu, Jianjun Deng, Ming Luo, Jie Ruan, Zhan Yang

{"title":"Using the National Nosocomial Infections Surveillance risk index to determine risk factors associated with surgical site infections following gynecologic surgeries.","authors":"Dong Wang, Jinlin Wu, Jianjun Deng, Ming Luo, Jie Ruan, Zhan Yang","doi":"10.5603/gpl.95073","DOIUrl":"10.5603/gpl.95073","url":null,"abstract":"Objectives: We used the National Nosocomial Infections Surveillance (NNIS) risk index to determine risk factors associated with surgical site infections (SSIs) following gynecologic surgeries.Material and methods: A retrospective study was conducted based on the medical records of 185 patients with SSIs, following gynecologic surgeries at a Grade A tertiary gynecologic and obstetric hospital in southwest China during September 2013-June 2021.Results: Suspected risk factors associated with SSIs were: length of hospital stay, age, whether the patient had cancer, whether the patient had chemotherapy or high-dose antibiotic therapy before surgery, duration of surgery, amount of blood loss, and whether a blood transfusion was done. It was found that SSIs were more likely to occur in cancer patients with an NNIS risk index score of 1 and in patients with preoperative chemotherapy and an NNIS risk index score of 2. Among the patients with an NNIS risk index score of 2, the older the patient, the higher incidence of SSIs.Conclusions: Gynecologic surgery teams should pay more attention to the independent risk factors associated with SSIs determined by the NNIS risk index score to prevent SSIs following gynecologic surgeries, thus ensuring patient safety.","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transvaginal single posterior incision extraperitoneal bilateral sacrospinous ligament suspension combined with reconstruction of pericervical ring through cervical cerclage. 经阴道单后切口腹膜外双侧骶棘韧带悬吊术，通过宫颈环扎重建宫颈环。

Ginekologia polska Pub Date : 2025-01-01 Epub Date: 2024-10-16 DOI: 10.5603/gpl.102089

Luo Puying, Yi Sijie, Luo Wenqun, Xiong Yuanhuan

引用次数: 0