Andrzej Jaworowski, Kuba Ptaszkiewicz, Bartosz Wrobel, Magdalena Kolak, Katarzyna Skibinska, Hubert Huras, Julia Jagiela
{"title":"Evaluating the impact of red blood cell parameters on outcomes of dinoprostone-induced labor: a retrospective study.","authors":"Andrzej Jaworowski, Kuba Ptaszkiewicz, Bartosz Wrobel, Magdalena Kolak, Katarzyna Skibinska, Hubert Huras, Julia Jagiela","doi":"10.5603/gpl.100356","DOIUrl":"https://doi.org/10.5603/gpl.100356","url":null,"abstract":"<p><strong>Objectives: </strong>This study explores the relationship between red blood cell parameters and perinatal outcomes in dinoprostone insert-induced labor at the Department of Obstetrics and Perinatology of the Jagiellonian University Medical College Cracow, Poland.</p><p><strong>Material and methods: </strong>Conducted between May 2019 and February 2021, this retrospective analysis included data on maternal age, pre-pregnancy BMI, hemoglobin level, red blood cell count, mean cell volume, and red cell distribution width, alongside newborn birthweight and Apgar scores. The study evaluated the impact of anemia, a hemoglobin level lower than 12 g/dL, on the likelihood of cesarean section, labor duration, delivery time, and neonatal outcomes.</p><p><strong>Results: </strong>With 183 participants, findings indicate no significant difference in perinatal outcomes between anemic and non-anemic groups, suggesting mild anemia may not significantly influence dinoprostone insert-induced labor outcomes.</p><p><strong>Conclusions: </strong>The study highlights the importance of a nuanced approach to managing anemia in pregnancy, emphasizing the necessity for individualized treatment strategies. Our findings contribute to the ongoing discourse on anemia management during pregnancy, underscoring the need for more targeted research to develop evidence-based guidelines.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min Li, Yanqing Wu, Guichun Tan, Lu Liu, Liming Wang, Ziming Huang, Xiaoling Tao, Xin Du
{"title":"Comparison of the efficacy of transumbilical single-port laparoscopy and traditional laparoscopy for type II/III cesarean scar pregnancy.","authors":"Min Li, Yanqing Wu, Guichun Tan, Lu Liu, Liming Wang, Ziming Huang, Xiaoling Tao, Xin Du","doi":"10.5603/gpl.99855","DOIUrl":"https://doi.org/10.5603/gpl.99855","url":null,"abstract":"<p><strong>Objective: </strong>To explore the differences in clinical and cosmetic efficacy between transumbilical single-port laparoscopy (TSPLS) and traditional laparoscopy for type II and III cesarean scar pregnancy (CSP).</p><p><strong>Methods: </strong>We retrospectively included 39 patients with type II and III CSP who were admitted to Hubei Maternal and Child Health Hospital for surgical treatment between June 2018 and June 2021 and classified them into Groups A and B according to patients' wishes. Patients in Group A (n = 15) were treated with TSPLS, and those in Group B (n = 24) were treated with traditional laparoscopy. Both groups underwent CSP resection and lower uterine segment repair via plastic surgery. Based on their condition and intraoperative bleeding, the patients were treated with uterine artery preligation. The operative time, preoperative pretreatment, intraoperative blood loss, decrease in beta-human chorionic gonadotropin (β-hCG) level, postoperative vaginal bleeding time, postoperative intestinal ventilation time, length of hospital stays, complications, and scar cosmesis assessment were compared.</p><p><strong>Results: </strong>The scar cosmesis score was significantly lower in Group A than in Group B (p < 0.01). No significant differences in intraoperative blood loss, absolute decrease in β-hCG level, absolute decrease in blood hemoglobin level, absolute increase in blood C-reactive protein level, postoperative vaginal bleeding time, postoperative intestinal ventilation time, length of hospital stay, and complications were observed between the two groups (p > 0.05). The operative time in the experimental group was slightly longer than that in the control group (p < 0.05).</p><p><strong>Conclusion: </strong>TSPLS had better cosmetic effects than traditional multi-port laparoscopy, without surgical results and postoperative recovery difference, making it valuable for clinical application.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The outcomes of the 5 mm versus 11 mm primary trocar in gynecologic surgery - randomised study.","authors":"Emin Erhan Dönmez, Zafer Bütün, Eyüpcan Kardas, Fisun Vural","doi":"10.5603/gpl.100621","DOIUrl":"https://doi.org/10.5603/gpl.100621","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the effects of using 11 mm trocar and 5 mm trocar as primary ports on postoperative pain in benign gynecological laparoscopic surgeries.</p><p><strong>Material and methods: </strong>The patients were divided into two groups as the primary port, group I (5 mm trocar) and group II (11 mm trocar) by block randomization.</p><p><strong>Results: </strong>In the 5 mm trocar group, postoperative pain score and need for analgesia were less in level I and level II operations. Patient satisfaction was significantly higher in the 5 mm trocar group. The postoperative pain score was higher in patients who had trocar insertion attempts 3 times with the direct trocar method compared to patients with 1 or 2 trocar entry attempts.</p><p><strong>Conclusions: </strong>The use of a 5 mm laparoscope in benign gynecological operations is an advantageous method due to low postoperative pain score, analgesic requirement, and high patient satisfaction.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective analysis of the effect of electronic cardiotocography on selected birth and neonatal variables among 4172 women from a Single Centre in Warsaw, Poland.","authors":"Sylwia Lidia Rychlewicz, Grazyna Baczek, Patryk Rzonca, Piotr Wegrzyn, Agnieszka Uryga, Justyna Teliga-Czajkowska","doi":"10.5603/gpl.103375","DOIUrl":"https://doi.org/10.5603/gpl.103375","url":null,"abstract":"<p><strong>Objectives: </strong>Cardiotocography (KTG) is widely used for continuous or intermittent assessment of fetal heart function. This study aimed to compare the effects of continuous and intermittent KTG during labour on selected variables.</p><p><strong>Material and methods: </strong>In a retrospective study, 4172 medical records of Warsaw Hospital (Poland) patients were analysed. The study group consisted of 2111 women with continuous KTG during labour and the control group of 2061 women with periodic KTG. The median age of the women was 30 years, and the median gestation period was 40 Hbd. Most of the women lived in urban areas (87.15%), were in a relationship (82.05%) and had a higher education (86.60%).</p><p><strong>Results: </strong>In the group with intermittent OCT, delivery by caesarean section was indistinguishably more frequent (OR = 1.06; 95% CI = 0.87-1.30), there were significantly fewer grade II perineal ruptures (OR = 1.65, 95% CI = 1.07-2.55), grade III- and IV perineal ruptures (OR = 5.13, 95% CI = 1.12-23.53) and oxygen therapy (OR = 1.76, p = 0.004). More infants with Apgar scores ≤ 7 points at the fifth minute (OR = 0.34, 95% CI = 0.12-0.094), requiring nCPAP (Nasal Continuous Positive Airway Pressure) (OR = 0.56, 95% CI = 0.39-0.86) and resuscitation [OR = 0.37, 95% CI = 0.17-0.79]) were born in the group with periodic ECG. The analysis showed that the group of women with continuous OCT during labour had a lower risk of acid-base disorders (OR = 0.45, 95% CI = 0.21-0.98) CONCLUSIONS: Continuous KTG during labour in high-risk women increases the likelihood of instrumental delivery (using vacuum) and perineal incision compared with periodic KTG. The use of intermittent ECG during labour reduces the number of newborns with Apgar scores ≤ 7 points and decreases the number of neonatal interventions such as nCPAP and resuscitation.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jakub Krawczyk, Aneta Czerwonogrodzka-Senczyna, Iwona Boniecka, Anna Jeznach-Steinhagen
{"title":"The role of Anti-Müllerian hormone in women health.","authors":"Jakub Krawczyk, Aneta Czerwonogrodzka-Senczyna, Iwona Boniecka, Anna Jeznach-Steinhagen","doi":"10.5603/gpl.96393","DOIUrl":"https://doi.org/10.5603/gpl.96393","url":null,"abstract":"<p><p>Anti-Müllerian hormone (AMH), also known as Müller duct inhibitory factor and primarily known for its role in sexual differentiation. In female fetuses, AMH production by granulosa cells begins around the 36th week of gestation and continues in women until menopause. It is becoming more significant in the endocrine and gynecological diagnosis of adult women. The suppressive effect of AMH on follicle-stimulating hormone (FSH)-induced aromatase production likely plays a role in hyperandrogenism in polycystic ovary syndrome (PCOS) and may increase insulin resistance. Female adolescent with type 1 diabetes (T1D) have an increased likelihood of developing PCOS, but it is not known whether they also show elevated AMH levels. The elevated AMH levels observed in prepubertal girls with T1D suggest that there are more small follicles in their ovaries, probably in response to insulin treatment. Elevated levels of androgens and anti-Müllerian hormone have been previously reported in non-pregnant women with diabetes. The increased AMH concentrations can be associated with reduced systemic inflammation [lower c-reactive protein (CRP) values], irrespective of the type of diet and greater insulin sensitivity in old obese males. AMH can also serve as a valuable marker for granulosa cell tumors (folliculomas) and their recurrence. In these clinical scenarios, AMH levels can be significantly elevated and correspond with the size of the tumor.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on the regulation of trophoblast activity by abnormally expressed hsa_circ_0002768 in patients with gestational diabetes mellitus.","authors":"Qian Liu, Lianzhi Wu","doi":"10.5603/gpl.99058","DOIUrl":"https://doi.org/10.5603/gpl.99058","url":null,"abstract":"<p><p>O: BJECTIVES: Circular RNAs (circRNAs) are known to be associated with the progression of gestational diabetes mellitus (GDM). Thus, the objective of this study was to unveil the influnce and potential mechanism of hsa_circ_0002768 in GDM. M: ATERIAL AND: METHODS: Levels of hsa_circ_0002768 were quantified by RT-qPCR. Placental hsa_circ_0002768 levels were analyzed after pregnancies. Trophoblast cell (HTR-8/SVneo) functions, including oxidative stress, mitochondrial dysfunction, cell viability, autophagy, and invasion, were evaluated upon hsa_circ_0002768 knockdown. Finally, the downstream miRNA for hsa_circ_0002768 was investigated. RESULTS: Hsa_circ_0002768 levels increased as high glucose-induced, and in GDM placenta. In vitro experiments showed that hsa_circ_0002768 knockdown positively regulated trophoblast oxidative stress and mitochondrial functions, thus inducing cell viability and invasion, but inhibiting autophagy. miR-339-5p was a downstream molecular for hsa_circ_0002768, which targeted to TLE3. CONCLUSIONS: This study reveals a physiological role for hsa_circ_0002768 during GDM.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrianna Perzanowska, Anna Korczak, Karol Taradaj, Tomasz Ginda, Grazyna Kmita, Yevonnie Chauraya, Wedu Ndebele, Elopy Sibanda, Bozena Kociszewska-Najman
{"title":"Comparative analysis of the risk of postpartum depression in Poland and Zimbabwe and identification of risk factors.","authors":"Adrianna Perzanowska, Anna Korczak, Karol Taradaj, Tomasz Ginda, Grazyna Kmita, Yevonnie Chauraya, Wedu Ndebele, Elopy Sibanda, Bozena Kociszewska-Najman","doi":"10.5603/gpl.102244","DOIUrl":"https://doi.org/10.5603/gpl.102244","url":null,"abstract":"<p><strong>Objectives: </strong>Postpartum depression is a common and serious mental health problem which is associated with maternal distress and negative consequences for the offspring. Research confirms the presence of differences in the prevalence of postpartum depression in different social groups. The aim of this study was to compare the severity of maternal symptoms in Poland and Zimbabwe and to identify risk factors occurring in both groups.</p><p><strong>Material and methods: </strong>The survey was conducted in 2022 among mothers who gave birth at the Department of Neonatology and Rare Diseases and at the Mpilo Central Hospital Maternity Clinic. The Edinburgh Postnatal Depression Scale was used to assess the risk of postnatal depression. A total of 945 patients were included.</p><p><strong>Results: </strong>The study indicated statistically significant differences in the percentage of women with an increased risk of postpartum depression, with the percentage for the Polish group being 13.54 % and the Zimbabwean group 35.74 %. For the Zimbabwean group, the risk of depression was associated with a problem in obtaining breastmilk and these were women in informal partnerships or those without a stable partner. In the group of Polish patients there was evidence of a correlation between increased risk and having a stable, non-formalised relationship.</p><p><strong>Conclusions: </strong>According to the analysis, women in Zimbabwe are more likely to be at risk of postpartum depression than Polish women. PPD remains an important issue in obstetric practice, and it is necessary to sensitize health care personnel to the risk of PPD to make timely and appropriate clinical interventions.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monika Kopec, Paula Szlendak, Jan Kotarski, Marek Gogacz
{"title":"The influence of ethanol consumption on a course of endometriosis.","authors":"Monika Kopec, Paula Szlendak, Jan Kotarski, Marek Gogacz","doi":"10.5603/gpl.103148","DOIUrl":"https://doi.org/10.5603/gpl.103148","url":null,"abstract":"<p><strong>Objectives: </strong>Due to the increasingly faster pace of life and responsibilities, stress has become an integral part of daily life. Every year, numerous social campaigns in the media raise the issue of increasing alcohol consumption. Endometriosis is a chronic, causally incurable, estrogen-dependent and inflammatory gynecological disorder, described as presence of ectopic endometrial tissue outside the uterine cavity. Some studies suggest that alcohol may aggravate the symptoms of the disease. The aim of the study is to present a comprehensive review reffering to the role of ethanol in the course of endometriosis.</p><p><strong>Material and methods: </strong>A review of the literature available in the PubMed database between 2000 and 2024 was conducted, using the following keywords: \"endometriosis\", \"alcohol\", \"ethanol\". The search included articles published in English. Publications without full text access and duplicates were rejected. 247 records were screened of which 15 met the eligilibity criteria, and 12 were included in this article.</p><p><strong>Results: </strong>Alcohol may affect estrogen production (by increasing the activity of aromatase and interacting with luteinizing hormone), promotes pro-inflammatory pathways and oxidative stress. It is also perceived as a form of self-management therapy resulting from pain, anxiety, and low self-esteem. Patients who are alcohol-dependent more often experience infertility, miscarriages, anovulation and ovarian pathologies.</p><p><strong>Conclusions: </strong>Although there is no clear evidence suggesting the adverse effect of ethanol on the course of endometriosis, the substance may be life-destroying in alcohol-dependent women. It may cause more severe course of endometriosis affecting many ascpectcts of life.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Botor, Karolina Bator, Szymon Stojko, Rafal Stojko, Agnieszka Drosdzol-Cop
{"title":"Sexual education around the world: in Australia and Oceania and Europe.","authors":"Anna Botor, Karolina Bator, Szymon Stojko, Rafal Stojko, Agnieszka Drosdzol-Cop","doi":"10.5603/gpl.103664","DOIUrl":"https://doi.org/10.5603/gpl.103664","url":null,"abstract":"<p><p>Sexual education is a vital process of teaching and learning about various aspects of human sexuality, including physical, emotional, social, and cultural dimensions. Its primary goal is to equip individuals, especially adolescents, with the necessary knowledge, skills, and values to make informed, responsible, and safe decisions regarding their sexual and reproductive lives. This article examines sexual education programs in Australia, Oceania, and Europe, addressing the current state, the unique challenges, and recommendations for enhancing these programs to meet the needs of modern society.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gynecological complications and treatment strategies in patients after hematopoietic stem cell transplantation.","authors":"Kinga Wdowiarz, Malgorzata Reinholz-Jaskolska, Malgorzata Radowicka, Miroslaw Wielgos, Bronislawa Pietrzak","doi":"10.5603/gpl.102573","DOIUrl":"https://doi.org/10.5603/gpl.102573","url":null,"abstract":"<p><p>In women after hematopoietic stem cell transplantation (HSCT), complications associated with the original disease and therapies used both before and after transplantation often occur, which significantly affects their quality of life. The most common gynaecological complications include secondary cancers, premature ovarian insufficiency (POI), infertility and chronic graft-versus-host disease (cGVHD). Cervical cancer is the most common secondary genital cancer in patients after HSCT. Regular screening and vaccination against HPV (Human Papillomavirus) can significantly reduce the risk for its occurrence. The specific complication after allogeneic hematopoietic stem cell transplantation is graft-versus-host disease (GVHD), the genital form of which can lead to labial and vaginal adhesions, significantly reducing the women's quality of life. The basis of treatment is local steroid therapy and immunosuppression. A consequence of chemotherapy and radiation therapy may be damage to the gonads leading to premature ovarian insufficiency and the onset of menopause symptoms. The basis of treatment is systemic hormone therapy used until middle age when natural menopause is reached. Women after HSCT who are of reproductive age also suffer from infertility. An important role of the doctor is to educate patients about the risk for infertility and to suggest appropriate methods of preserving fertility before starting treatment. The recommended procedure for fertility preservation is cryopreservation of embryos or oocytes. The freezing and retransplantation of ovarian tissue is becoming an increasingly popular method of fertility protection. Preventive examinations and early detection and treatment of gynaecological complications significantly improve the comfort of life and health of women after HSCT.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}