Ginekologia polska最新文献

{"title":"Clear cell carcinoma with lung metastasis arising from endometriosis in the abdominal surgical scar - management with a multidisciplinary mode.","authors":"Chi Yuan Liao, Fuh Jinn Luo, Fang Ling Chiu, Jan Sing Hsieh","doi":"10.5603/gpl.103947","DOIUrl":"https://doi.org/10.5603/gpl.103947","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal hypoplastic left heart syndrome and neonatal follow-up in Polish Mother's Memorial Hospital Research Institute report from January 2023 to January 2024: an improvement of survival rate.","authors":"Maria Respondek-Liberska, Iwona Strzelecka, Maciej Slodki, Michal Krekora, Mariusz Grzesiak, Ewa Gulczynska, Iwona Maroszynska, Tomasz Moszura, Edward Malec, Katarzyna Januszewska","doi":"10.5603/gpl.104906","DOIUrl":"https://doi.org/10.5603/gpl.104906","url":null,"abstract":"<p><strong>Objectives: </strong>In 2023 and 2024, our primary study group consisted of 39 fetuses with HLHS MATERIAL AND METHODS: From the final analysis, we excluded the following: 1 twin pair (twin A with normal heart anatomy and twin B with HLHS), 2 terminations of pregnancy, and 2 newborns without prenatal echocardiography (only ultrasound was performed, and HLHS was not detected prenatally). As a result, our study group comprised 34 fetuses. The mean gestational age at the detection of HLHS was 19 weeks (± 6 weeks). Extracardiac malformations were present in 7 fetuses out of 34. Prenatally diagnosed genetic problems included Turner syndrome, DiGeorge syndrome, and an abnormal Y chromosome.</p><p><strong>Results: </strong>Most pregnancies ended at term, with a mean gestational age at delivery of 38.5 weeks (± 0.9). The mean birth weight was 3142 g, and the mean Apgar score was 8 at 1 minute. After birth, there were 2 neonatal deaths: one newborn with HLHS and a birth weight of 1900 g, and another with HLHS and lymphangiectasies. Norwood surgery was performed in 32 newborns: in survivors, at a mean age of 12 ± 5 days, and in the non-survivor group, at a mean of 17 ± 5 days (t-test p = 0.027). The overall survival rate from 2023 to 2024 was 87% for liveborn fetuses/neonates, significantly higher than the historical data from 2008-2015, which showed a survival rate of 64% (chi-square p = 0.015).</p><p><strong>Conclusions: </strong>Prenatal echocardiographic data do not equate to cardiac surgery data, as they include deaths in utero, terminations of pregnancy, and deaths after delivery (presurgery mortality). In consultations with future parents following the prenatal detection of HLHS, the entire spectrum of possible outcomes should be discussed, including the survival rate after Norwood surgery at our center, which was approximately 90% from January 2023 to January 2025. The day of cardiac surgery may be an additional important risk factor.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstetric and neonatal risks of Streptococcus agalactiae in adolescent pregnancy: a retrospective matched cohort study.","authors":"Jakub Staniczek, Maisa Manasar-Dyrbus, Rafal Stojko, Aleksandra Matonog, Katarzyna Wilk-Sikora, Maja Zieba-Domalik, Jonasz Troszka, Szymon Stojko, Agnieszka Drosdzol-Cop","doi":"10.5603/gpl.105549","DOIUrl":"https://doi.org/10.5603/gpl.105549","url":null,"abstract":"<p><strong>Objectives: </strong>Streptococcus agalactiae (GBS) infection is significant in obstetric and neonatal complications. Maternal age, particularly adolescent pregnancy, may influence the prevalence of GBS colonization and associated clinical outcomes. This study aimed to evaluate the impact of maternal age on obstetric and neonatal outcomes, with a specific focus on the modifying effect of GBS status. The analysis explored whether the associations between maternal age and selected outcomes remained statistically significant after adjusting for GBS interactions.</p><p><strong>Material and methods: </strong>A retrospective matched cohort study was conducted with 582 participants, comprising a study group and a matched control group selected through propensity score matching. The study group included adolescents (≤ 19 years, n = 194) and older individuals (> 19 years, n = 388). Inclusion criteria required GBS screening after the 35th week of gestation, bacterial culture upon hospital admission, and delivery during the same hospitalization. Statistical analyses included logistic and linear regression models adjusted for interactions with GBS.</p><p><strong>Results: </strong>In unadjusted analyses, adolescent mothers showed a higher likelihood of postpartum hemorrhage (OR = 2.715, p = 0.02), uterine atony (OR = 3.594, p = 0.043), transient tachypnea of the newborn (TTN) (OR = 6.16, p = 0.027), and shorter neonatal length (Estimation = -0.791, p = 0.001). However, after adjusting for interactions with GBS, these associations lost statistical significance: postpartum hemorrhage (AOR = 0.67, p = 0.711), uterine atony (AOR = 2.417, p = 0.315), TTN (AOR = 4.87, p = 0.117), and neonatal length (Estimation = -0.207, p = 0.584).</p><p><strong>Conclusions: </strong>These findings indicate that GBS colonization confounds the observed relationships between maternal age and these outcomes. These results underscore the importance of accounting for GBS status in assessing age-related risks during pregnancy and tailoring clinical management accordingly.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life satisfaction and self-efficacy of nurses and midwives in caring for newborns with lethal anomalies.","authors":"Katarzyna A Urbańska, Beata M Naworska, Karolina Bednarz, Szymon Stojko, Agnieszka B Drosdzol-Cop","doi":"10.5603/gpl.104634","DOIUrl":"https://doi.org/10.5603/gpl.104634","url":null,"abstract":"<p><strong>Objectives: </strong>The nursing and midwifery professions are potential influences on life satisfaction and self-efficacy, especially in obstetric settings dealing with fetal demise or severe congenital anomalies. This study aimed to assess how sociodemographic factors (e.g., workplace, marital status, financial situation, occupation, and tenure) and specific job exposures (frequency of neonatal death and caregiving for newborns with lethal defects) impact life satisfaction and self-efficacy among nurses and midwives. The study further explored the role of employer-provided psychological support in influencing job satisfaction and self-efficacy.</p><p><strong>Material and methods: </strong>A diagnostic survey with a custom questionnaire, supplemented by the General Self-Efficacy Life satisfaction and self-efficacy (GSES) and Satisfaction with Life Scale (SWLS), was conducted in level II and III referral centers in Poland's Silesian region in 2023. Participants included nurses and midwives in various neonatal and obstetric departments. Statistical analyses encompassed descriptive statistics, chi-square tests, and Spearman correlations, with significance set at p < 0.05.</p><p><strong>Results: </strong>A majority of participants reported moderate to high life satisfaction (41.7%) and self-efficacy (59.0%). Key factors impacting life satisfaction included marital status, financial situation, education, tenure, and caregiving frequency for newborns with lethal defects. High self-efficacy was significantly associated with job satisfaction, tenure, and workplace environment but was unaffected by marital status, financial situation, or psychological support.</p><p><strong>Conclusions: </strong>The findings highlight the emotional burden on nurses and midwives in neonatal care. Enhanced psychological support, stress-coping training, and policy adjustments are recommended to support this workforce. Further studies should broaden regional scope and examine links between life satisfaction, self-efficacy, and job satisfaction.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ectopic pregnancy - a comparision of treatment methods in terms of effectiveness and impact on fertility.","authors":"Wojciech Zieba, Grzegorz Guzowski, Piotr Sieroszewski","doi":"10.5603/gpl.101849","DOIUrl":"https://doi.org/10.5603/gpl.101849","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to compare the available methods of treating a pregnancy located in the fallopian tube with regard to their efficacy and impact on patient fertility.</p><p><strong>Material and methods: </strong>The retrospective study involved a total of 217 patients treated at the Department of Fetal Medicine and Gynaecology at the Medical University of Lodz between 2018 and 2023. Medical records were analysed and a telephone survey was carried out to assess the follow-up of patients after discharge from the Department.</p><p><strong>Results: </strong>84% of patients were qualified for surgical treatment achieving a combined success rate of both methods (salpingotomy and salpingectomy) close to 100%. No positive effect on fertility of preserving the fallopian tube after pregnancy termination compared to removal of the fallopian tube was observed. The method with the highest risk of recurrent fallopian tube pregnancy was salpingotomy.</p><p><strong>Conclusions: </strong>The results of this study show surgical treatment as the option for the treatment of pregnancy located in the fallopian tube. Appropriate qualification of patients allows to choose optimal therapeutic strategy. A positive effect on further fertility of the salpingotomy strategy compared to salpingectomy has not been demonstrated.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The feasibility of gasless single-port access laparoscopy in overweight patients undergoing adnexal surgery.","authors":"Jong Ha Hwang, Bo Wook Kim","doi":"10.5603/gpl.101987","DOIUrl":"https://doi.org/10.5603/gpl.101987","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the feasibility and outcomes of gasless single-port access (SPA) laparoscopy in overweight patients undergoing adnexal surgery.</p><p><strong>Material and methods: </strong>A retrospective review was conducted on the medical records of 118 patients who underwent gasless SPA laparoscopic adnexal surgery using J-shaped or triangular-shaped retractors between May 2017 and June 2022. Patients were categorized into overweight (BMI ≥ 23) and standard-weight (BMI < 23) groups. Surgical characteristics and outcomes were compared between the two groups.</p><p><strong>Results: </strong>Out of 118 patients, 41 were in the overweight group, and 77 were in the standard-weight group. Significant differences were observed in age (p = 0.001), the number of previous abdominal surgeries (p = 0.001), and the number of subjects who had given birth (p = 0.004), all higher in the overweight group. There were no significant differences between the groups in setup time from umbilical skin incision to abdominal wall retraction, use of additional TROCARS: operation time, estimated blood loss, or length of postoperative hospital stay. No serious intraoperative complications, such as urologic, bowel, and vessel injuries were noted in either group. Tumor diameter (p < 0.001), bilaterality (p < 0.001), presence of adhesion (p = 0.026), and setup diameter of the retractor (p = 0.001) significantly correlated with operation time in multivariate analysis (Adjusted R² = 0.645).</p><p><strong>Conclusions: </strong>Gasless SPA laparoscopic adnexal surgery in overweight patients is a feasible and effective alternative to conventional SPA laparoscopy, mitigating the potential negative effects of carbon dioxide gas.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the regulation of trophoblast activity by abnormally expressed hsa_circ_0002768 in patients with gestational diabetes mellitus.","authors":"Qian Liu, Lianzhi Wu","doi":"10.5603/gpl.99058","DOIUrl":"https://doi.org/10.5603/gpl.99058","url":null,"abstract":"<p><p>O: BJECTIVES: Circular RNAs (circRNAs) are known to be associated with the progression of gestational diabetes mellitus (GDM). Thus, the objective of this study was to unveil the influnce and potential mechanism of hsa_circ_0002768 in GDM. M: ATERIAL AND: METHODS: Levels of hsa_circ_0002768 were quantified by RT-qPCR. Placental hsa_circ_0002768 levels were analyzed after pregnancies. Trophoblast cell (HTR-8/SVneo) functions, including oxidative stress, mitochondrial dysfunction, cell viability, autophagy, and invasion, were evaluated upon hsa_circ_0002768 knockdown. Finally, the downstream miRNA for hsa_circ_0002768 was investigated. RESULTS: Hsa_circ_0002768 levels increased as high glucose-induced, and in GDM placenta. In vitro experiments showed that hsa_circ_0002768 knockdown positively regulated trophoblast oxidative stress and mitochondrial functions, thus inducing cell viability and invasion, but inhibiting autophagy. miR-339-5p was a downstream molecular for hsa_circ_0002768, which targeted to TLE3. CONCLUSIONS: This study reveals a physiological role for hsa_circ_0002768 during GDM.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early intervention prevented intrauterine fetus death due to placental abruption in woman with JAK2V617F mutation-positive essential thrombocythemia.","authors":"Artur Handziuk, Dominika Galli, Aleksandra Pralat, Zuzanna Kandula, Krzysztof Lewandowski, Wieslaw Markwitz","doi":"10.5603/gpl.101184","DOIUrl":"10.5603/gpl.101184","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"324-325"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is it possible to predict severe postpartum hemorrhage and the need for massive transfusion in placenta previa cases?","authors":"Emre Köle, Bertan Akar, Emek Doğer, Merve Çakır Köle, Yonca Anık, Eray Çalışkan","doi":"10.5603/gpl.103049","DOIUrl":"10.5603/gpl.103049","url":null,"abstract":"<p><strong>Objectives: </strong>The aim was to construct a reliable working model for patients with placenta previa (PP) that aids in the prediction of postpartum bleeding potential with data from antenatal imaging studies using both ultrasound (US) and magnetic resonance imaging (MRI).</p><p><strong>Material and methods: </strong>Forty-three patients with PP were evaluated initially with the US and then by 3-Tesla MRI. The Placenta Accreata Index (PAI) was used during the US evaluation in order to define the risks. Uterine bulging, heterogeneous signal, dark placental bands, focal interruption of myometrium and tenting of bladder wall were regarded as predictive criteria in MRI evaluation. The correlation between the findings from US and MRI studies and subsequent haemorrhage, < 1000 mL, > 1000 mL and severe haemorrhage ( > 2000 mL) and massive transfusion [ > 5 units of red blood cells (RBC)] were used to build this predictive model. The findings from the imaging studies were also confirmed histopathologically.</p><p><strong>Results: </strong>In the multivariate analysis of data from patients stratified by bleed size either < 1000 mL or > 1000 mL, none of the MRI and ultrasound findings were found to be predictive. The multivariate analysis was done using the second stratification cut-point of 2000 mL, in patients bleeding > 2000 mL PAI values [OR: 2.3 (1.4-3.8)] and overall MRI reported placenta accreata spectrum [OR: 4.9 (1.8-12.9)] were found to be predictive. While MRI findings were not discriminative between transfusion groups, grade 3 loculation on US examination was found to be predictive for the need of transfusion of > 5 units [OR: 67.5 (8.2-549.4)]. There were no cases needing hysterectomy.</p><p><strong>Conclusions: </strong>Ultrasound and MRI findings in cases of PP can be helpful in predicting postpartum bleeding.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"308-313"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations vulvar lichen sclerosus with autoimmune thyroid diseases.","authors":"Maja J Zieba-Domalik, Dominika Orszulak, Kacper Nizinski, Katarzyna Wilk, Marta Janik, Rafal Stojko, Agnieszka Drosdzol-Cop","doi":"10.5603/gpl.103145","DOIUrl":"10.5603/gpl.103145","url":null,"abstract":"<p><strong>Objectives: </strong>Vulvar lichen sclerosus (VLS) is defined as a chronic inflammatory skin disease that most often involves lesions on the mucous membranes of the vulva with a tendency to progress to the anal skin. The etiopathogenesis of VLS remains unknown and is likely multifactorial. Data emphasize the role of immunological factors - more than 25% of VLS cases coexist with autoimmune diseases. The purpose of the present study was to determine the correlation of the prevalence of anti-thyroid antibodies - IgG class antibodies against thyroid peroxidase and IgG class antibodies against thyroglobulin in women with vulvar lichen sclerosus, and the appropriateness of screening tests for autoimmune thyroid diseases in women with vulvar lichen sclerosus.</p><p><strong>Material and methods: </strong>Fifty women with vulvar lichen sclerosus were enrolled in the study. The control group consisted of 41 healthy women. A detailed medical history was taken with all patients, followed by laboratory determinations - anti-thyroid antibodies - IgG class antibodies against thyroid peroxidase and IgG class antibodies against thyroglobulin.</p><p><strong>Results: </strong>Antibodies to thyroid peroxidase were present in 12% of the study group with vulvar lichen sclerosus and 4.88% of the control group, and this difference was not statistically significant (p = 0.41). Anti-thyroglobulin antibodies were detected in 4% of the patients with vulvar lichen sclerosus and 4.88% of the control group, and this difference was not statistically significant either (p = 0.76).</p><p><strong>Conclusions: </strong>The study did not confirm the association of VLS with autoimmune thyroid diseases. Undoubtedly, based on the data available in the literature, further studies are needed to determine the mechanisms behind the association between vulvar lichen sclerosus and autoimmune thyroid diseases.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":"235-240"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}