Ginekologia polska最新文献

{"title":"Significance of apparent diffusion coefficient in the diagnosis of endometrial carcinoma and its pathohistological features.","authors":"Milica Zorić, Milica Šarošković, Jelena Vuković, Igor Nosek, Nataša Prvulović Bunović, Miloš Vuković","doi":"10.5603/gpl.103995","DOIUrl":"https://doi.org/10.5603/gpl.103995","url":null,"abstract":"<p><strong>Objectives: </strong>MR differentiation between endometrial cancer, hyperplasia, and the normal endometrium using ADC values and their correlation with the pathohistological characteristics of endometrial cancer.</p><p><strong>Material and methods: </strong>The retrospective study included 131 patients, 55 with endometrial cancer, 21 with hyperplasia, and 55 patients with normal endometrium. Mean ADC values were obtained by measuring the region of interest (ROI) in the corresponding part of the endometrium.</p><p><strong>Results: </strong>The mean ADC values of endometrial cancer (0.646 ± 0.112 × 10⁻³ mm²/s) were significantly lower than those of endometrial hyperplasia (1.660 ± 0.394 × 10⁻³ mm²/s) and normal endometrium (1.503 ± 0.312 × 10⁻³ mm²/s) (p<0.001), while the ADC values of endometrial hyperplasia did not differ from normal endometrium. No difference was found between ADC values in different grades of endometrial cancer (p=0.219; p>0.05), depending on the depth of myometrial invasion (p=0.506; p>0.05), the presence of metastases in lymph nodes (p=0.202; p>0.05), and lymphovascular invasion (p=0.366; p>0.05). Regarding the FIGO stage, the only significant difference in ADC values was obtained for stage 4b (p=0.023; p<0.05). ADC values below 1.120 × 10⁻³ mm²/s with 100% sensitivity and 94.5% specificity indicate the presence of cancer, with a positive predictive value of 94.8% and a negative predictive value of 100%.</p><p><strong>Conclusions: </strong>The ADC is a useful diagnostic tool in the differentiation between endometrial cancer and hyperplasia with high sensitivity and specificity, but its use in differentiating pathohistological characteristics of endometrial cancer is not possible.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Diagnostic Parameters of Cytodiagnostics as a screening tool conducted in 2005-2020 as part of the National Population-Based Cervical Cancer Screening Program in Poland.","authors":"Klaudyna Madziar, Maria Buda, Witold Kedzia","doi":"10.5603/gpl.98522","DOIUrl":"https://doi.org/10.5603/gpl.98522","url":null,"abstract":"<p><strong>Objectives: </strong>We assessed the diagnostic parameters of cytodiagnosis as a screening method used in the National Population-Based Cervical Cancer Screening Program compared to out-program screening.</p><p><strong>Material and methods: </strong>A retrospective analysis of 800 results obtained during routine screening for the National Population-Based Cervical Cancer Screening Program and out-program samples. Abnormal cytologic interpretations, which were an indication for colposcopy as well as HPV DNA HR test and the final histopathology test, both from in- and out-program patients, were statistically analyzed.</p><p><strong>Results: </strong>Out of 800 abnormal cytologic results, we obtained 7 - suspicion of squamous cell carcinoma, 105 - HSIL, 152 - ASC-H, 269 - LSIL, 254 - ASCUS, and 13 - AGC. Cervical pathology was confirmed on histopathology in 422 patients: cervical cancer was detected in 21 patients, with the following findings in the remaining women: 103 - CIN 3, 126 - CIN 2, 173 - CIN 1, koilocytosis without CIN - 143, and lesion-free histopathology - 378. Out of 800 abnormal cytologic results, HPV DNA was detected in 539 women, including 387 - HPV DNA HR, 240 - HPV DNA 16, and only 22 - HPV DNA 18.</p><p><strong>Conclusions: </strong>The prevention program significantly improved the detection parameters of the in-program as compared to out-program cytodiagnostics. The goal of the screening programs should be to identify lesions consistent with ≥ CIN2. Molecular testing, which can identify at least 14 HPV HR genotypes, should be the first-line screening tool. A positive molecular test result should not be an indication for advanced diagnostics. Other than conventional or liquid-based cytology, an ultimate detection test is necessary.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 40:1 myo-inositol/D-chiro-inositol treatment on serum asprosin levels in polycystic ovary syndrome: a prospective randomized pilot study.","authors":"Ozlen Emekci Ozay, Yusuf Ozay, Oguzhan Edebal, Marco Calcagno, Ali Cenk Ozay","doi":"10.5603/gpl.103763","DOIUrl":"https://doi.org/10.5603/gpl.103763","url":null,"abstract":"<p><strong>Objectives: </strong>Asprosin, a novel adipokine primarily secreted by white adipose tissue, has been implicated in the pathogenesis of insulin resistance and metabolic dysfunction. Its elevated levels characterize patients with polycystic ovary syndrome (PCOS) exhibiting metabolic alterations. Aim of this work was to evaluate the effects of insulin sensitizer administration, as inositols, on asprosin levels and then compare these results with the effects of metformin treatment.</p><p><strong>Material and methods: </strong>30 patients with PCOS were enrolled in this study and randomly divided into two groups: (i) group 1 assumed a dietary supplement based on 40:1 myo-inositol (MI)/D-chiro-inositol (DCI), (ii) group 2 assumed metformin (MET), for 12-16 weeks of treatment.</p><p><strong>Results: </strong>The reduction of serum asprosin levels in patients with PCOS after treatment with MET and MI/DCI is the most intriguing result. Its levels decreased more in the inositol group, although they did not reach statistical significance probably due to the lower number of patients.</p><p><strong>Conclusions: </strong>The observed dysregulation of asprosin levels in PCOS highlights a potential link between this novel adipokine and the pathophysiology of the disorder, suggesting a modulatory effect of the combined 40:1 MI/DCI on asprosin levels. Of course, further studies may contribute to disclosing molecular mechanisms underlying asprosin reduction and open toward new perspectives.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colposcopy in pregnancy.","authors":"Edyta Keczkowska, Natalia Zeber-Lubecka, Katarzyna Szlendak-Sauer, Monika Nekanda-Trepka, Maciej Brazert, Michal Ciebiera","doi":"10.5603/gpl.104421","DOIUrl":"https://doi.org/10.5603/gpl.104421","url":null,"abstract":"<p><p>Colposcopy is a method of enhanced diagnostics of cervical dysplasia, aimed at preventing cervical cancer. Its role is the same in and out of pregnancy. It is often performed after obtaining abnormal results of cervical cytology or a test for human papillomavirus (HPV16 and HPV18), or any other abnormal findings such as polyps, or unexplained bleeding from the cervix. However, in pregnancy, the first screening test is still a cytological examination of the cervical smear. Colposcopy allows for the identification of suspicious lesions, which allows for a biopsy to be collected for histopathological evaluation. Biopsy is not recommended during pregnancy except for the detection of lesions suspected of being invasive. Colposcopy is minimally invasive, generally well tolerated and crucial for the early detection of cervical intraepithelial neoplasia (CIN) and other gynecological lesions. In pregnancy, this role is reduced to observing the cervix for the progression of lesions. Pregnancy-related lesions in the cervix sometimes make it difficult to assess the cervix effectively and reliably. Therefore, the experience of the physician performing colposcopy during pregnancy is of great importance. In this review we want to summarize the current data about colposcopy during pregnancy.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of antenatal magnesium sulfate on feeding intolerance and necrotizing enterocolitis in preterm infants.","authors":"Ipek Guney Varal, Gaffari Tunc, Hilal Kucuk, Dilge Sener, Ayse Oren","doi":"10.5603/gpl.104549","DOIUrl":"https://doi.org/10.5603/gpl.104549","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effects of antenatal magnesium sulfate administration on preterm gastrointestinal feeding intolerance and necrotizing enterocolitis in preterm infants.</p><p><strong>Material and methods: </strong>This observational cohort, single-centre study included preterm infants < 30 weeks gestational age or < 1250 g, who were admitted to the neonatal intensive care unit of a university hospital. These infants were divided into two groups on the basis of having received antenatal magnesium sulfate or not.</p><p><strong>Results: </strong>Overall, 118 preterm infants were enrolled. Fifty-four of these infants had received prenatal magnesium sulfate (Group 1), and 64 (42%) had not (Group 2) before their neonatal intensive care unit (NICU) admission. The number of days to full eneteral feeding and the days of total parenteral nutrition were significantly higher in Group 2 than in Group 1 (p < 0.05). When gestational age, birth weight, and small for gestational age (SGA) were included as factors affecting feeding intolerance, the logistic regression analysis results showed that the administration of magnesium sulfate was an independent risk factor (adjusted OR: 3.5; 95% CI: 1.462-8.615; p < 0.05). Antenatal magnesium sulfate administration was not observed to have an effect on spontaneous intestinal perforation and necrotising enterocolitis.</p><p><strong>Conclusions: </strong>The administration of antenatal magnesium sulfate has proven tocolytic and neuroprotective effects on preterm births. However, it must be taken into consideration that it can cause feeding intolerance in preterm infants without causing intestinal injury.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rectocele.","authors":"Krzysztof Lippki, Beata Rutkowska, Katarzyna Szczubelek-Pietrzykowska, Ewa Monika Barcz","doi":"10.5603/gpl.104320","DOIUrl":"https://doi.org/10.5603/gpl.104320","url":null,"abstract":"<p><p>Rectocele is one of the more common pathologies of the pelvic floor. It is a clinical problem that significantly worsens the quality of life by causing obstructed defecation symptoms such as anal digitation, incomplete emptying, and dyschesia. Proper differential diagnosis, distinguishing rectocele from enterocoele or perineal body descent, allows for making proper therapeutic decisions and consists of medical history, ultrasound examination, dynamic magnetic resonance imaging (MRI), and defecography. The most common treatment procedures are vaginal native tissue repair, transanal repair, and laparoscopic ventrorectopexy. Surgical treatment should aim to alleviate the symptoms of obstructed defecation and repair the anatomical issue.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation analysis of ultrasound features with ER, PR, HER-2, P53, nuclear proliferation factor Ki-67, TOPIIa, and cytokeratin CK5/6 immunohistochemistry in non-mass infiltrating ductal carcinoma of the breast.","authors":"Huihui Peng, Yuanyuan Zhu, Yao Li","doi":"10.5603/gpl.98797","DOIUrl":"https://doi.org/10.5603/gpl.98797","url":null,"abstract":"<p><strong>Objectives: </strong>The goal is for investigating the correlation between ultrasound features and molecular pathological markers such as estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2), tumor protein p53, nuclear proliferation factor Ki-67, DNA topoisomerase IIα (Topo II), and cytokeratin CK5/6 in non mass infiltrating ductal carcinoma of the breast.</p><p><strong>Material and methods: </strong>A total of 125 sufferers with non mass infiltrating ductal carcinoma of the breast were included in the ultrasound images and immunohistochemical results. This study analyzed the characteristics of ultrasound images, including maximum cross-sectional diameter, morphology, peripheral hyperechoic halo, hair prick sign, and micro-calcification, as well as the positive expression of molecular pathological markers (ER, PR, HER-2, p53, Ki-67, Topo II, CK5/6); It uses statistical methods for evaluating the correlation between ultrasound features and molecular pathological markers.</p><p><strong>Results: </strong>In 125 patients, the maximum cross-sectional diameter was markedly related to positive expression of CK5/6 (r = 0.176, p < 0.05), Ki-67 (r = 0.328, p < 0.05), and HER-2 (r = 0.468, p < 0.05). There is a marked relation between posterior echo attenuation and ER positivity (r = 0.096, p < 0.05) and Topo II positivity (r =-0.021, p < 0.05). However, there was no marked relation in morphology, peripheral hyperechoic halo, hairline sign, and micro-calcification with prognostic molecular pathological markers (p > 0.05).</p><p><strong>Conclusions: </strong>This study found a marked relation in the maximum cross-sectional diameter of non mass infiltrating ductal carcinoma of the breast and the positive expression of CK5/6, Ki-67, and HER-2. This finding suggests that the maximum cross-sectional diameter may serve as a potential indicator for prognostic evaluation and is closely related to the expression of cytokeratin CK5/6, nuclear proliferation factor Ki-67, and HER-2 in tumors. Posterior echo attenuation is closely related to ER positive and Topo II expression. No significant correlation was observed between morphology, peripheral hyperechoic halo, hairline sign, and micro-calcification with prognostic molecular pathological markers. These results provide new insights for the prognosis evaluation of patients with non mass infiltrating ductal carcinoma of the breast and contribute to the development of individualized treatment strategies, but further research and validation are still needed.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between plasma Afamin and gestational diabetes mellitus during pregnancy.","authors":"Xiang Cheng, Hongyan Cui, Xinran Xu, Nini Jiang","doi":"10.5603/gpl.103660","DOIUrl":"https://doi.org/10.5603/gpl.103660","url":null,"abstract":"<p><strong>Objectives: </strong>We investigated the correlation of plasma Afamin levels with gestational diabetes mellitus (GDM) during pregnancy and assessed its predictive value for the risk and prognosis of GDM.</p><p><strong>Material and methods: </strong>A total of 993 pregnant women were included in this nested case-control study. The fasting blood samples in their first trimester were collected. Ninety-one women were diagnosed with GDM, and they were subdivided into insulin treatment group (Group A1, 30 cases) and non-insulin treatment group (Group A2, 61 cases) according to whether they needed to treat with insulin. Another 91 pregnant women with normal glucose tolerance were as the control group (NC group). The plasma and umbilical cord blood levels of Afamin were measured in the first and second trimesters using enzyme-linked immunosorbent assay (ELISA). The correlation of Afamin levels with GDM during pregnancy and its predictive value were assessed.</p><p><strong>Results: </strong>Plasma Afamin levels in both GDM groups (A1 and A2) were significantly higher than in the control group at all pregnancy stages (p < 0.01). Afamin levels in the second trimester were significantly higher in Group A1 than those in Group A2 (p < 0.05). Multivariate logistic regression identified that plasma Afamin levels in the first trimester (OR = 1.126, 95% CI: 1.032-1.228, p = 0.008) and in the second trimester (OR = 1.173, 95% CI: 1.092-1.259, P = 0.000) were the independent risk factors for GDM, along with insulin resistance index (OR = 1.62, 95% CI: 1.036-2.534, p = 0.034). ROC analysis showed optimal cut-off value of plasma Afamin was 65.90 mg/L in the first trimester (AUC = 0.858, sensitivity = 75.8%, specificity = 85.7%) and 85.09 mg/L in the second trimester (AUC = 0.874, sensitivity = 92.3%, specificity = 76.9%).</p><p><strong>Conclusions: </strong>Elevated plasma Afamin levels during the first and second trimesters are associated with GDM, supporting Afamin level as a potential biomarker for early GDM risk prediction.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of clear cell carcinoma based on iatrogenic endometriosis - case series.","authors":"Michal Stojko, Szymon Stojko, Natalia Leszczynska, Kamil Nikel, Agnieszka Drosdzol-Cop","doi":"10.5603/gpl.105718","DOIUrl":"https://doi.org/10.5603/gpl.105718","url":null,"abstract":"<p><p>Iatrogenic endometriosis, a rare form of endometriosis resulting from surgical interventions, has become increasingly recognized as a complication of cesarean sections. This study examines the development of clear cell carcinoma (CCC) arising from endometrial tissue implanted in cesarean section scars. Based on a review of 41 clinical cases, the study highlights the challenge in diagnosis and management of this uncommon aggressive malignancy. The average delay from cesarean section to diagnosis was 18 years, with common symptoms being painful masses and scar tenderness. Imaging modalities such as magnetic resonance imaging (MRI) and computed tomography (CT) were the first diagnostic tools, while biopsy confirmed malignancy in most cases. The outlook for patients who had CCC in cesarean scars was extremely poor, and scant long-term survival data existed. These observations serve to reemphasize the necessity of increased awareness by gynecologists and obstetricians of the risk potential associated with cesarean delivery. Improved diagnostic scrutiny, especially in the patient who comes to the doctor with unexplained symptoms involving the scar, is recommended in this study. A strong role is also supported in informed choice before surgical modes of delivery are attempted.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women's sexual quality of life after ectopic pregnancy surgery - vNOTES vs conventional laparoscopy - a retrospective cohort study.","authors":"Mustafa Cengiz Dura, Cihan Kaya, Berk Gürsoy, Özgür Aslan, Şükrü Yıldız, Murat Ekin","doi":"10.5603/gpl.104355","DOIUrl":"https://doi.org/10.5603/gpl.104355","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the postoperative sexual function and recovery outcomes between women who underwent vNOTES (vaginal natural orifice transluminal endoscopic surgery) and those who underwent conventional laparoscopy (CL) for ectopic pregnancies.</p><p><strong>Material and methods: </strong>A retrospective cohort study was conducted with data from 98 patients who underwent CL or vNOTES for ectopic pregnancy. Postoperative sexual function and genital self-image were evaluated using the Female Sexual Function Index (FSFI) and Female Genital Self-Image Scale (FGSIS) surveys, respectively. Patients were divided into the vNOTES group (n = 40) and the CL group (n = 58).</p><p><strong>Results: </strong>The postoperative FSFI total scores did not significantly differ between the vNOTES group and the CL group (p = 0.384). However, the lubrication subgroup score of the FSFI was significantly higher in the CL group compared to the vNOTES group (p = 0.001). The FGSIS total score was significantly higher in the vNOTES group compared to the CL group (p = 0.009).</p><p><strong>Conclusions: </strong>While vNOTES surgery may offer some postoperative benefits in terms of genital self-image, it is associated with lower lubrication scores compared to conventional laparoscopy. These findings highlight the potential impact of vNOTES on sexual function, emphasizing the need for further research to optimize surgical approaches that balance sexual function and recovery outcomes.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}