Ginekologia polska最新文献

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Nonpharmacological mental health interventions for adolescent patients with polycystic ovary syndrome: a scoping review.
Ginekologia polska Pub Date : 2025-03-12 DOI: 10.5603/gpl.102733
Tian Zheng, Jia Li, Jing Chao, Hong Lian Wang, Ying Hui, Lan Shen
{"title":"Nonpharmacological mental health interventions for adolescent patients with polycystic ovary syndrome: a scoping review.","authors":"Tian Zheng, Jia Li, Jing Chao, Hong Lian Wang, Ying Hui, Lan Shen","doi":"10.5603/gpl.102733","DOIUrl":"https://doi.org/10.5603/gpl.102733","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to summarize nonpharmacological mental health interventions that are beneficial for adolescent patients with polycystic ovary syndrome (PCOS) and to identify the limitations of existing studies.</p><p><strong>Material and methods: </strong>Following the recommendations of the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-SCR), we conducted a scoping review of nonpharmacological interventions aimed at improving mental health in adolescents with PCOS.</p><p><strong>Results: </strong>Six randomized controlled trials (RCTs), two quasiexperimental studies, two case reports, one prospective study, one predictive correlation study, and one field trial study were included, resulting in 13 articles. Nonpharmacological interventions encompass a range of psychotherapies, dietary modifications, physical exercise, and traditional Chinese medicine therapies. Except for one study that has not yet reported findings, all included studies reported significant improvements in patients' mental health through nonpharmacological interventions.</p><p><strong>Conclusions: </strong>The evidence summarized in this study suggests that nonpharmacological interventions may be efficacious in improving the mental well-being of adolescent patients with PCOS. However, existing studies have limitations, including small sample sizes, the limited use of outcome indicators, and a lack of postintervention follow-up evaluations. Therefore, further RCTs should be conducted to validate the effectiveness and safety of current or alternative nonpharmacological interventions.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The value of miRNAs as a biomarker for the diagnosis of gestational diabetes mellitus: a meta-analysis. miRNA 作为诊断妊娠糖尿病生物标志物的价值:一项荟萃分析。
Ginekologia polska Pub Date : 2025-03-12 DOI: 10.5603/gpl.100165
Feng Zhao, Guolei Wang
{"title":"The value of miRNAs as a biomarker for the diagnosis of gestational diabetes mellitus: a meta-analysis.","authors":"Feng Zhao, Guolei Wang","doi":"10.5603/gpl.100165","DOIUrl":"https://doi.org/10.5603/gpl.100165","url":null,"abstract":"<p><strong>Objectives: </strong>The present meta-analysis evaluated the value of miRNAs in the diagnosis of gestational diabetes mellitus (GDM).</p><p><strong>Material and methods: </strong>Eligible studies were gathered from MEDLINE, EMBASE, PubMed, Chinese National Knowledge Infrastructure (CNKI), WanFang, and CQVIP information databases. Combined sensitivity, specificity, and summary receiver operating characteristic (SROC) curves of enrolled studies were analyzed using STATA 12.0. Diagnostic accuracy was examined by diagnostic likelihood ratio (DLR), diagnostic score, and diagnostic odds ratio (DOR). Publication bias was calculated using Deeks' funnel plot.</p><p><strong>Results: </strong>18 articles (29 studies) were included in this meta-analysis. The pooled sensitivity of overall miRNAs was 0.83 (95% CI = 0.77-0.88), and the specificity was 0.79 (95% CI = 0.72-0.84). The area under SROC curve (AUC) was 0.88 (95% CI = 0.85-0.90). The positive DLR was 3.94 (95% CI = 2.98-5.21), and the negative DLR was 0.22 (95% CI = 0.16-0.30). The diagnostic score was 2.91 (95% CI = 2.44-3.37), and the DOR was 18.27 (95% CI = 11.44-29.17). These results suggest that miRNAs have high diagnostic accuracy for GDM. High heterogeneity may be caused by study design, gestational age, and cutoff value. Subgroup analysis indicates that sensitivity and specificity are higher in case-control studies than in cohort studies. Specificity differs significantly in the cutoff value subgroup.</p><p><strong>Conclusions: </strong>Overall, miRNAs showed high accuracy in diagnosing of metabolic changes in GDM patients. High heterogeneity may be caused by study design, sampling gestational age, and cutoff value.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Classification of hemostatic methods and their efficacy in placenta increta.
Ginekologia polska Pub Date : 2025-03-12 DOI: 10.5603/gpl.93988
Caihong Hu, Weishe Zhang, Lijuan Liu, Xiaowen Zhang, Hongtao Zeng, Qi Li, Jingrui Huang
{"title":"Classification of hemostatic methods and their efficacy in placenta increta.","authors":"Caihong Hu, Weishe Zhang, Lijuan Liu, Xiaowen Zhang, Hongtao Zeng, Qi Li, Jingrui Huang","doi":"10.5603/gpl.93988","DOIUrl":"https://doi.org/10.5603/gpl.93988","url":null,"abstract":"<p><strong>Introduction: </strong>Placenta increta is a serious complication of pregnancy that needs a variety of intraoperative hemostatic methods to stop bleeding. However, the efficacy of different hemostatic methods is still not known. This study aimed to evaluate the efficacy of different hemostatic methods in placenta increta.</p><p><strong>Material and methods: </strong>A total of 187 placenta increta patients that underwent treatment at Xiangya Hospital Central South University from March 1, 2017 to January 31, 2021 were included in this retrospective study. Perioperative data of patients with placenta increta were retrospectively analyzed. The patients were distributed into two groups according to the hemostasis methods, namely permanent group (n = 29), permanent plus temporary group (n = 158). Permanent hemostasis included the subgroups of uterine hemostasis (e.g., uterine tamponade, B-Lynch suture, and uterine local suture) and vascular hemostasis (e.g., uterine artery ligation and internal iliac artery ligation). The clinical information and maternal-fetal outcomes of the groups and subgroups were analyzed.</p><p><strong>Results: </strong>A significant difference in blood loss was detected between the permanent hemostasis group and the permanent plus temporary hemostasis group. Compared with the uterine hemostatic, the vascular, and combined hemostatic methods had a significant reduction in postpartum blood loss (p < 0.05). No differences were found within these subgroups in the permanent plus temporary group. Pregnancy outcomes did not differ significantly among the subgroups.</p><p><strong>Conclusions: </strong>Vascular hemostasis and combined hemostasis may be better than uterine hemostasis alone for placenta increta without temporary hemostasis. Prospective and large-scale studies are needed to investigate long-term outcomes and confirm the efficacy of these hemostatic techniques.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-sample Mendelian randomization analysis of the causal relationship between lipid metabolism/fatty acid metabolism and pre-eclampsia. 对脂质代谢/脂肪酸代谢与先兆子痫之间因果关系的双样本孟德尔随机分析。
Ginekologia polska Pub Date : 2025-03-12 DOI: 10.5603/gpl.101256
Dan Yang, Jin Chen, Xiaoyin Wang, Lin Zhuang, Hongjun Feng, Xue Liao, Ting Mo
{"title":"Two-sample Mendelian randomization analysis of the causal relationship between lipid metabolism/fatty acid metabolism and pre-eclampsia.","authors":"Dan Yang, Jin Chen, Xiaoyin Wang, Lin Zhuang, Hongjun Feng, Xue Liao, Ting Mo","doi":"10.5603/gpl.101256","DOIUrl":"https://doi.org/10.5603/gpl.101256","url":null,"abstract":"<p><strong>Objectives: </strong>A causal relationship has been found between the abundance of some flora in the gut microbiota and the development of pre-eclampsia (PE). Short-chain fatty acids in gut microbes are an important source of lipids. The causal effect of lipid metabolism/fatty acid metabolism pathways on PE exposure is unknown.</p><p><strong>Material and methods: </strong>This study was based on single nucleotide polymorphism (SNP) data related to lipid metabolism/fatty acid metabolism and PE from the genome-wide association study (GWAS) in the GWAS Catalog database and finngen database, and a two-sample mendelian randomization (MD) analysis was performed to explore the causal relationship between lipid/fatty acid metabolism and PE exposure. Five MD analysis methods were used in this study, inverse-variance weighted (IVW), MR-Egger regression, weighted median (WM), weighted median estimator (WME), MR-PRESSO. The intercept term of MR-Egger regression was tested for the presence of genetic pleiotropy between SNPs and PEs. Cochran's Q test was performed to investigate the heterogeneity between variables. The leave-one-out method was used for sensitivity analysis to determine the robustness of the results.</p><p><strong>Results: </strong>Inverse-variance weighted results showed that gamma-glutamyl glutamine levels [odds ratio (OR) = 0.40, 95% confidence interval (CI): 0.21-0.78; p = 0.01], 1-arachidonoylglycerophosphocholine [1-arachidonoyl-sn-glycero-3-phosphocholine levels (OR = 0.57; 95% CI: 0.38-0.87; p = 0.01), X-14304--leucylalanine levels (OR = 0.72; 95% CI :0.56-0.93; p = 0.01), citrulline levels (OR = 0.48; 95% CI: 0.26-0.89; p = 0.02), inosine levels (OR = 0.88; 95% CI: 0.78-0.98; p = 0.02), and HWESASXX levels (OR = 0.64; 95% CI: 0.42-1.00; p = 0.05) were negatively correlated with PE. There was a positive trend for X-14205--alpha-glutamyltyrosine levels (OR = 1.55; 95% CI: 1.12-2.14; p = 0.01), X-11787 levels (OR = 3.29; 95% CI: 1.23-8.78; p = 0.02) to be associated with PE. No significant heterogeneity or pleiotropy was found for instrumental variables or levels pleiotropy.</p><p><strong>Conclusions: </strong>This study demonstrated a causal relationship between eight fatty acid metabolisms and PE. Follow-up in-depth randomized controlled trials are needed to reveal the promotional or protective effects of fatty acid metabolism on PE.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retained intrauterine device as cause of thrombotic thrombocytopenic purpura. 宫内节育器残留是血栓性血小板减少性紫癜的病因。
Ginekologia polska Pub Date : 2025-02-18 DOI: 10.5603/gpl.101684
Mateusz Klimek, Aleksandra Machnik, Monika Białowas, Krzysztof Nowosielski, Andrzej Witek
{"title":"Retained intrauterine device as cause of thrombotic thrombocytopenic purpura.","authors":"Mateusz Klimek, Aleksandra Machnik, Monika Białowas, Krzysztof Nowosielski, Andrzej Witek","doi":"10.5603/gpl.101684","DOIUrl":"https://doi.org/10.5603/gpl.101684","url":null,"abstract":"","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of mismatch repair (MMR), p53, and LCAM-1 immunohistochemical expression on prognosis in low-risk endometrial cancer. 错配修复(MMR)、p53 和 LCAM-1 免疫组化表达对低危子宫内膜癌预后的影响。
Ginekologia polska Pub Date : 2025-02-18 DOI: 10.5603/gpl.101983
Şener Gezer, Büşra Yaprak Bayrak, Müzeyyen Dilşad Eser, Esra Betül Tunce
{"title":"The impact of mismatch repair (MMR), p53, and LCAM-1 immunohistochemical expression on prognosis in low-risk endometrial cancer.","authors":"Şener Gezer, Büşra Yaprak Bayrak, Müzeyyen Dilşad Eser, Esra Betül Tunce","doi":"10.5603/gpl.101983","DOIUrl":"https://doi.org/10.5603/gpl.101983","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the relationship between mismatch repair (MMR) deficiency, TP53, and L1 cell adhesion molecule (L1CAM) immunohistochemical staining and their impact on progression-free survival (PFS) and overall survival (OS) in low-risk endometrial cancer.</p><p><strong>Material and methods: </strong>A total of 253 low-risk endometrial cancer patients were retrospectively screened. Immunohistochemical stains were applied to tumor tissue samples to assess MMR deficiency, TP53, and L1CAM expression, and survival analysis were performed.</p><p><strong>Results: </strong>The expected PFS time was 78.6 months for the MMR-proficient group and 70.3 months for the MMR-deficient group (p = 0.011). OS was 71.6 months for the MMR-proficient group and 68.2 months for the MMR-deficient group (p = 0.755). L1CAM overexpression was associated with a poorer PFS, 62.7 months compared to 77.7 months (p = 0.039). However, there was no statistically significant difference in OS, 58.5 months versus 72.1 months, respectively (p = 0.242). p53 abnormal (p53-abn) staining was associated with a worse prognosis in terms of PFS, 62.8 months versus 77.7 months (p = 0.035), and OS, 43.4 months versus 73 months, respectively (p < 0.001), compared to patients with wild-type staining. No significant statistical relationship was observed in survival times concerning tumor diameter, grade, and lymphadenectomy status. In a multivariate analysis, MMR deficiency emerged as an independent poor prognostic factor for PFS, while p53-abn was identified as an independent poor prognostic factor for OS.</p><p><strong>Conclusions: </strong>p53-abn staining was associated with a poor prognosis for both PFS and OS in low-risk endometrial cancer patients. Meanwhile, MMR deficiency and L1CAM positivity were found to be associated solely with a poorer prognosis for PFS.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neoadjuvant chemotherapy in patients with vulvar carcinoma: a systematic review. 外阴癌患者的新辅助化疗:系统综述。
Ginekologia polska Pub Date : 2025-02-18 DOI: 10.5603/gpl.97789
Magda Piechowicz, Wojciech Staskiewicz, Joanna Spaczyska, Milosz Pietrus, Kazimierz Pitynski
{"title":"Neoadjuvant chemotherapy in patients with vulvar carcinoma: a systematic review.","authors":"Magda Piechowicz, Wojciech Staskiewicz, Joanna Spaczyska, Milosz Pietrus, Kazimierz Pitynski","doi":"10.5603/gpl.97789","DOIUrl":"https://doi.org/10.5603/gpl.97789","url":null,"abstract":"<p><p>Neoadjuvant chemotherapy is one of the options of treating patients with vulvar carcinoma. In this systematic review we searched three databases (Medline, EMBASE, Cochrane Library) for literature regarding this method of therapy. Additional sources were also searched. We included primary studies of any design with no language or date restrictions. Fourteen full-text studies were found; due to heterogeneity of data no quantitative synthesis was performed. Quality of evidence was very low, mainly due to population sizes and no available comparative data with other types of treatment. The results were mixed, however some of the studies reported promising results regarding survival and possibility of more conservative surgery. In general chemotherapy was well-tolerated, but in some studies regimens containing bleomycin and methotrexate presented particularly severe toxicity.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic evaluation of systemic immune inflammatory index and hematological parameters in postpartum hemorrhage: a retrospective analysis.
Ginekologia polska Pub Date : 2025-02-18 DOI: 10.5603/gpl.100739
Emrullah Akay, Gizem Şirin Donbalıoğlu, Ali Selçuk Yeniocak, Emrah Dağdeviren, Can Tercan, İbrahim Polat
{"title":"Prognostic evaluation of systemic immune inflammatory index and hematological parameters in postpartum hemorrhage: a retrospective analysis.","authors":"Emrullah Akay, Gizem Şirin Donbalıoğlu, Ali Selçuk Yeniocak, Emrah Dağdeviren, Can Tercan, İbrahim Polat","doi":"10.5603/gpl.100739","DOIUrl":"https://doi.org/10.5603/gpl.100739","url":null,"abstract":"<p><strong>Objectives: </strong>Postpartum hemorrhage (PPH) is a significant global health risk for mothers. This study investigated the predictive capacity of the systemic immune inflammatory index (SII) to assess the risk of PPH. The SII, which is predicated on cell types of integral to inflammatory processes, correlates with high values of increased inflammatory activity and potentially adverse prognoses.</p><p><strong>Material and methods: </strong>This retrospective cohort study included female patients aged 15-49 diagnosed with PPH who continued to bleed post-treatment, received transfusions of four or more units of erythrocyte suspension, or underwent laparotomy/re-laparotomy.</p><p><strong>Results: </strong>The study found that Hemoglobin, hematocrit, platelet, and SII values were significantly lower, and lymphocyte counts were elevated in the PPH group. Both univariate and multivariate analyses identified hemoglobin and SII levels as significant determinants of PPH. An SII cutoff value of 915 proved to be an effective predictor of PPH. In subjects with an SII ≥ 915, leukocyte, platelet, and neutrophil values were higher, and lymphocyte counts were lower. Furthermore, the rates of PPH and Intensive Care Unit admissions increased in this cohort.</p><p><strong>Conclusions: </strong>The findings suggest that the SII is a potentially significant marker for PPH risk prediction. Elevated SII levels beyond the threshold of 915 were associated with heightened PPH risk of PPH.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The feasibility of gasless single-port access laparoscopy in overweight patients undergoing adnexal surgery.
Ginekologia polska Pub Date : 2025-02-11 DOI: 10.5603/gpl.101987
Jong Ha Hwang, Bo Wook Kim
{"title":"The feasibility of gasless single-port access laparoscopy in overweight patients undergoing adnexal surgery.","authors":"Jong Ha Hwang, Bo Wook Kim","doi":"10.5603/gpl.101987","DOIUrl":"https://doi.org/10.5603/gpl.101987","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the feasibility and outcomes of gasless single-port access (SPA) laparoscopy in overweight patients undergoing adnexal surgery.</p><p><strong>Material and methods: </strong>A retrospective review was conducted on the medical records of 118 patients who underwent gasless SPA laparoscopic adnexal surgery using J-shaped or triangular-shaped retractors between May 2017 and June 2022. Patients were categorized into overweight (BMI ≥ 23) and standard-weight (BMI < 23) groups. Surgical characteristics and outcomes were compared between the two groups.</p><p><strong>Results: </strong>Out of 118 patients, 41 were in the overweight group, and 77 were in the standard-weight group. Significant differences were observed in age (p = 0.001), the number of previous abdominal surgeries (p = 0.001), and the number of subjects who had given birth (p = 0.004), all higher in the overweight group. There were no significant differences between the groups in setup time from umbilical skin incision to abdominal wall retraction, use of additional TROCARS: operation time, estimated blood loss, or length of postoperative hospital stay. No serious intraoperative complications, such as urologic, bowel, and vessel injuries were noted in either group. Tumor diameter (p < 0.001), bilaterality (p < 0.001), presence of adhesion (p = 0.026), and setup diameter of the retractor (p = 0.001) significantly correlated with operation time in multivariate analysis (Adjusted R² = 0.645).</p><p><strong>Conclusions: </strong>Gasless SPA laparoscopic adnexal surgery in overweight patients is a feasible and effective alternative to conventional SPA laparoscopy, mitigating the potential negative effects of carbon dioxide gas.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal obesity, more than diabetes mellitus, predisposes to soft tissue injuries of the birth canal during vaginal delivery.
Ginekologia polska Pub Date : 2025-02-11 DOI: 10.5603/gpl.100252
Aneta Malinowska-Polubiec, Malgorzata Kujko-Wisniewska, Ewa Romejko-Wolniewicz, Julia Zareba-Szczudlik, Agnieszka Dobrowolska-Redo, Joanna Kacperczyk-Bartnik, Krzysztof Czajkowski
{"title":"Maternal obesity, more than diabetes mellitus, predisposes to soft tissue injuries of the birth canal during vaginal delivery.","authors":"Aneta Malinowska-Polubiec, Malgorzata Kujko-Wisniewska, Ewa Romejko-Wolniewicz, Julia Zareba-Szczudlik, Agnieszka Dobrowolska-Redo, Joanna Kacperczyk-Bartnik, Krzysztof Czajkowski","doi":"10.5603/gpl.100252","DOIUrl":"https://doi.org/10.5603/gpl.100252","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to evaluate the relationship between the incidence of birth canal soft tissue injuries, perineal incision procedure and maternal and neonatal characteristics.</p><p><strong>Material and methods: </strong>It was a retrospective cohort study conducted in a tertiary hospital analyzing deliveries between July 2018 and January 2019. Study group included 726 spontaneous vaginal singleton births in the longitudinal cephalic fetal position after completed 36th gestational week. Characteristics of patients who suffered from cervical ruptures and/or vaginal injuries were compared to those who gave birth without any soft tissue traumas.</p><p><strong>Results: </strong>The perineal incision procedure was performed in 561 (77.3%) women. Soft tissue injuries of the birth canal were found in 220 patients (30.3%). Cervical rupture was more frequent when perineal incision was performed (94.5% vs 74.2%, p = 0.0001), but only in primiparous women (70.6% vs 43.2%, p = 0.01). Vaginal injury happened less frequently when perineal incision was performed (56.5% vs 81.8%, p = 0.001), but only in multiparous women (12.9% vs 34.3%, p = 0.001). Vaginal injury was more common in women with higher pre-pregnancy body weight (69.4 vs 65.4 kg, p = 0.0015), higher prepregnancy BMI (24.5 vs 23.5 kg/m², p = 0.0085), higher body weight and BMI before delivery (82.2 vs 78.1 kg, p = 0.001 and 29.1 vs 28.1 kg/m², p = 0.008, respectively). In multivariate logistic regression analysis neither parity nor perineal incision increased the risk of vaginal injury. Only the obese women, but not diabetic, were at higher risk of vaginal injury, when perineal incision was performed (OR 2.25, CI 1.25-4.05, p = 0.007).</p><p><strong>Conclusions: </strong>The obese women are at higher risk of vaginal injury during delivery, when perineal incision is performed. The necessity of maintaining normal body weight while planning pregnancy, monitoring gestational weight gain, and avoiding perineal incision remain important issues.</p>","PeriodicalId":94021,"journal":{"name":"Ginekologia polska","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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