Is there a relationship between genital hiatus distance and the presence of pelvic organ prolapse?

Erdinç Dinçer, Fatih Tarhan
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Abstract

Objectives: Pelvic organ prolapse (POP) is an important disease affecting the quality of life of women. We aimed to investigate the relationship of genital hiatus (GH) and anogenital distance (AGD) measurements with POP in patients with lower urinary tract symptoms.

Material and methods: 1696 Patients who underwent urodynamic investigations in our clinics were evaluated retrospectively. Demographic data, physical examination data and urodynamic investigation results of all patients were evaluated. Those beyond POPQ stage 2 and above were considered to have pelvic organ prolapse.

Results: The mean age was 49.44 ± 0.27 years, and the mean body-mass index was 30.08 ± 0.16 kg/m². While 682 patients (40.2%) were considered as having no POP, 1014 patients (59.8%) were considered as having POP. A statistically significant difference was found between the groups in terms of POP status respect of the parity, mean GH and AGD, and hysterectomy rate (p < 0.05). Mean GH, PB and AGD were significantly different among POP stage groups. (p < 0.05). In the correlation analysis, there was a positive correlation between POP stage parity (p = 0.0003, r = 0.059), GH (p < 0.0001, r = 0.353) and AGD (p < 0.0001, r = 0.299). The logistic regression revealed that genital hiatus distance and hysterectomy were statistically significant factors associated with POP. In ROC analysis, when the GH distance measurement is > 2.5 cm, the probability of POP status was found with sensitivity of 77.4% and specificity of 53.2% (p < 0.001).

Conclusions: GH measurement can be marker for POP in a population of women being evaluated for urinary incontinence. GH measurement > 2.5 cm may associated with POP status.

生殖器裂孔距离与盆腔器官脱垂是否有关系?
目的:盆腔器官脱垂(POP)是影响女性生活质量的重要疾病。我们旨在探讨下尿路症状患者生殖器间隙(GH)和肛门生殖器距离(AGD)测量与POP的关系。材料和方法:回顾性分析我院门诊接受尿动力学检查的1696例患者。对所有患者的人口学资料、体格检查资料和尿动力学调查结果进行评估。超过POPQ 2期及以上的患者被认为有盆腔器官脱垂。结果:患者平均年龄49.44±0.27岁,平均体质指数30.08±0.16 kg/m²。682例(40.2%)为无POP, 1014例(59.8%)为有POP。两组间胎次POP状况、平均GH、AGD、子宫切除率比较,差异均有统计学意义(p < 0.05)。各组间平均GH、PB、AGD差异有统计学意义。(p < 0.05)。在相关分析中,POP分期胎次(p = 0.0003, r = 0.059)、GH (p < 0.0001, r = 0.353)和AGD (p < 0.0001, r = 0.299)呈正相关。logistic回归分析显示,生殖器裂孔距离和子宫切除术是影响POP的有统计学意义的因素。在ROC分析中,当GH距离测量为> 2.5 cm时,发现POP状态的概率敏感性为77.4%,特异性为53.2% (p < 0.001)。结论:生长激素测量可作为评估尿失禁的女性人群中POP的标志物。GH测量> 2.5 cm可能与POP状态有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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