Ear, nose, & throat journal最新文献

{"title":"A Case of Mature Cystic Teratoma of the Floor of Mouth With Cleft Palate in Newborn.","authors":"Cuimei Zhang, Yuelin Qin, Fang Wang, Xuecai Yang, Junwei Wang","doi":"10.1177/01455613251341154","DOIUrl":"https://doi.org/10.1177/01455613251341154","url":null,"abstract":"<p><p>Dermoid cysts, also known as mature cystic teratomas (MCTs), are congenital tumors that originate from all 3 germ layers. While commonly found in the ovary or testis, they are rare occurrences in the floor of the mouth. This case report describes a rare case of neonatal cleft palate with MCT of the floor of the mouth. The report provides a comprehensive analysis of the clinical manifestations, imaging characteristics, pathological findings, and surgical management strategies employed in this rare case to enhance clinicians' knowledge regarding uncommon tumors in the head and neck of newborns. Through the discussion of this case, the importance of preoperative evaluation, rapid intraoperative diagnosis, and long-term postoperative follow-up is further emphasized.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251341154"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Cervical Subcutaneous Emphysema Following Swimming.","authors":"Jonathan Abou Chaar, Ibana Carapiperis, Rita Maria Jalkh, Randa Al Barazi","doi":"10.1177/01455613251325116","DOIUrl":"https://doi.org/10.1177/01455613251325116","url":null,"abstract":"<p><p>Subcutaneous cervical emphysema refers to the presence of air or gas trapped beneath the skin in the neck or cervical region. It typically occurs when air is introduced into the tissues due to trauma, infection, or medical procedures that disrupt the respiratory tract. Diagnosis is based on clinical presentation in addition to chest and neck radiographic examinations. Subcutaneous cervical emphysema resulting from swimming is extremely rare, and patients may be asymptomatic or present with crepitus, neck swelling, and dysphonia. In severe cases, life-threatening complications can occur, such as airway compromise or tension pneumothorax. The authors of this manuscript report a rare case of a 9-year-old female, previously healthy, who presented with subcutaneous cervical emphysema following a swimming training session. This patient was followed up for 1 month with conservative management and experienced self-resolution of her symptoms. Early diagnosis, monitoring, and initiation of treatment are highly recommended to prevent any long-term or life-threatening complications.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251325116"},"PeriodicalIF":0.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Where There is Smoke: An Updated Review of Environmental Contributions to Chronic Rhinosinusitis.","authors":"Christopher J Hill","doi":"10.1177/01455613251337885","DOIUrl":"https://doi.org/10.1177/01455613251337885","url":null,"abstract":"<p><strong>Purpose: </strong>The pathogenesis of chronic rhinosinusitis (CRS) is thought to include a complex interaction between environmental exposures and host immune responses that generates a self-perpetuating inflammatory process. As molecular pathways continue to be explored, the impact of environmental exposures on CRS pathogenesis and exacerbation must not be overlooked. This review will explore the association between environmental exposures and CRS, specifically focusing on tobacco smoke, occupational inhalational exposures, air pollution, particulate matter, and wildfire smoke.</p><p><strong>Major findings: </strong>Tobacco smoke is associated with increased prevalence of CRS symptoms and formal diagnosis with worse surgical outcomes observed in both adults and children exposed to tobacco smoke. Numerous occupational exposures have been associated with increased sinonasal symptoms, though exposures and disease definitions are often poorly characterized. Pollution and microparticle exposure has been associated with an increased likelihood of CRS diagnosis, as well as increased need for surgery. Last, while wildfire smoke has been attributed to increased hospital and emergency room visits for respiratory-related complaints, no primary research has yet been performed regarding CRS and wildfire smoke, though in-vitro studies support an association.</p><p><strong>Conclusions: </strong>Population-based studies bolstered by in-vitro mechanistic data support an association between numerous environmental exposures and the onset and severity of CRS.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251337885"},"PeriodicalIF":0.0,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomogram to Predict the Risk of External Auditory Canal Stenosis After Endoscopic Surgery: A Retrospective Study.","authors":"Zhongxuan Yao, Shao Yudi, Peng Yaxin, He Jiadi, Wei Li","doi":"10.1177/01455613251339757","DOIUrl":"https://doi.org/10.1177/01455613251339757","url":null,"abstract":"<p><strong>Objective: </strong>To identify risk factors and develop a predictive model for the onset of external auditory canal stenosis (EACS) after endoscopic surgery.</p><p><strong>Patients and methods: </strong>A retrospective analysis was conducted in 362 patients who underwent endoscopic surgery from January 2021 to September 2023. The patients were categorized into a training set (n = 217) and a test set (n = 145). A single-factor regression analysis was used to identify significant differences between the EACS and non-EACS groups within the training set. Least absolute shrinkage and selection operator (LASSO) regression analysis and multivariate logistic regression were employed to screen and develop predictive models, visualized in a nomogram. The predictive accuracy of the nomogram was assessed using receiver operating characteristic (ROC) curves, calibration plots, decision curve analysis (DCA), and clinical impact curves (CIC).</p><p><strong>Results: </strong>Univariate regression analysis of the training set revealed that the history of EACS, the history of ear surgery, the operative time, the levels of triglycerides (TG), the systemic immune-inflammation ratio (SIRI), and the albumin-to-creatinine score (AISI) were significant factors between the 2 groups (<i>P</i> < .05). Subsequently, these variables were included in the LASSO regression analysis, which identified 4 high-risk factors: history of ear surgery, operative time, TG levels, and SIRI. The model exhibited strong predictive capacity, with an area under the ROC curve of 0.89 (95% CI 0.82-0.95) in the training set and 0.88 (95% CI 0.72-1.00) in the validation set. Calibration curves, DCA, and CIC analyses further demonstrated the model's excellent predictive value and clinical utility.</p><p><strong>Conclusions: </strong>The developed nomogram is a significant tool for predicting postoperative EACS in patients undergoing endoscopic surgery. It offers a valuable reference for the early identification of high-risk patients, facilitating timely clinical intervention and promoting personalized and precise treatment strategies.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251339757"},"PeriodicalIF":0.0,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastatic Breast Cancer Presenting as Clival Mass Extending into Sphenoid Sinus.","authors":"Ahmed Nadeem-Tariq, Taimur Khalid, Emily S Sagalow, Caroline Liu, Joel S Bentz, Sisi Tian, Jo-Lawrence Bigcas","doi":"10.1177/01455613251338919","DOIUrl":"https://doi.org/10.1177/01455613251338919","url":null,"abstract":"<p><p>Metastasis to the clivus and sphenoid sinus from breast cancer is exceedingly rare, with few cases documented in the literature. This case report presents a 68-year-old female with a history of breast cancer who developed metastasis to the clivus extending into the sphenoid sinus. The clinical presentation, diagnostic challenges, and therapeutic interventions are discussed, with a review of similar cases in the literature to highlight the importance of early recognition and multidisciplinary management.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251338919"},"PeriodicalIF":0.0,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data-Driven Analysis of Short- and Long-Term Outcomes of Simulation, Nasal Hump Reduction, and Rasping in Open Rhinoplasty for Nasal Dorsum Correction.","authors":"Fuat Bulut, Faruk Bulut","doi":"10.1177/01455613251334450","DOIUrl":"https://doi.org/10.1177/01455613251334450","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to highlight the significance of performing simulations, nasal hump reduction, and rasping in open-technique rhinoplasty for the nasal dorsum. The research utilizes data science methodologies for a thorough examination of the collected survey data.</p><p><strong>Methods: </strong>A comprehensive survey comprising 29 questions was presented to surgeons participating in the Eastern Trakya ENT Association Training Meetings-I. This survey, specifically designed to investigate the nuances of open and closed rhinoplasty approaches to nasal dorsum intervention, collected responses from 132 physicians. The collected dataset was thoroughly reviewed and analyzed. The responses were not only graphically represented but also transformed into a dataset primed for data science analysis. Significant results were derived using both association rule-mining algorithms from machine learning and basic statistical analysis.</p><p><strong>Results: </strong>The raw data underwent thorough analysis using fundamental statistical methods and association rules within the field of data science. The discerned data patterns revealed significant insights into the behavioral tendencies and approaches adopted by physicians in rhinoplasty. The survey analysis emphasized the widespread acceptance of the open technique for nasal dorsum procedures, even though it may not be the preferred choice for all rhinoplasty cases. A notable 74.6% of rhinoplasty surgeons employing the open technique indicated that the primary long-term challenge during nasal dorsum interventions was irregularity. In addition, among the 132 participating surgeons, 25.8% were found to frequently engage in facial plastic surgery, while 55.4% reported abstaining from simulations. Notably, rhinoplasty surgeons who opted out of simulations, despite exclusively applying the open technique, reported encountering irregularities and requiring more adjustments.</p><p><strong>Conclusion: </strong>Rhinoplasty surgeons who do not use simulations in open nasal dorsum approaches reported facing irregularities and performing more revisions. Furthermore, they noted encountering irregularities in both the short and long term following nasal hump reduction and rasping procedures.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251334450"},"PeriodicalIF":0.0,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Post-Intubation Cricoid Cartilage Abscess: Diagnosis and Therapeutic Approach.","authors":"Majd Werda, Rania Laajailia, Ayoub Smaoui, Malek Mnejja, Ilheme Charfeddine","doi":"10.1177/01455613251341147","DOIUrl":"https://doi.org/10.1177/01455613251341147","url":null,"abstract":"<p><p>We report a life-threatening post-intubation cricoid abscess in a 29-year-old diabetic male, highlighting the challenges of airway compromise management. Following 7 days of mechanical ventilation for severe pneumonia, the patient developed acute dysphonia, inspiratory stridor, and progressive dyspnea culminating in resting respiratory distress (ambulation <10 m). Bedside laryngoscopy revealed a 70% obstructing subglottic mass with inflammatory changes. Contrast computed tomography identified a 23 mm rim-enhancing cricoid abscess causing critical airway stenosis. Immediate tracheostomy secured the airway, with subsequent operative drainage yielding <i>Streptococcus</i> species resistant to first-line antibiotics. Targeted IV ceftazidime and oral ciprofloxacin achieved resolution, permitting decannulation at 21 days. This case underscores 3 critical lessons: (1) the heightened infection risk in diabetics post-intubation, (2) the value of rapid endoscopic airway assessment in post-extubation dyspnea, and (3) the necessity of culture-directed therapy in deep neck space infections. Unlike typical laryngotracheal complications (eg, granulomas or stenosis), abscess formation at the cricoid represents a rare but potentially fatal etiology of post-intubation airway obstruction requiring multidisciplinary intervention. Early imaging and surgical drainage proved pivotal in preventing catastrophic outcomes in this immunocompromised host.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251341147"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-Specific Factors to Differentiate Between Branchial Cleft Cysts and CUP Syndrome: A 10 Year Unicenter Study.","authors":"Christina Sauter, Matthias Sand, Peter K Plinkert, Karim Plath, Carlo Cavaliere, Michaela Plath","doi":"10.1177/01455613251337985","DOIUrl":"https://doi.org/10.1177/01455613251337985","url":null,"abstract":"<p><strong>Objectives: </strong>Due to its generally-poor prognosis and varied clinical presentation, cervical cancer of unknown primary (CUP) poses particular challenges for clinical and imaging diagnosis. Differential diagnoses of CUP syndrome may also include lateral cervical cysts. When a benign neck cyst is initially suspected, squamous cell carcinoma is often diagnosed after receiving histopathology. Our study investigates the risk factors to differentiate between CUP syndrome and lateral neck cysts (LNC) to possibly improve the prognosis.</p><p><strong>Methods: </strong>Between 2013 and 2023, 244 patients with an initial diagnosis of LNC (n = 121) or CUP (n = 123) were recruited from the Department of Otorhinolaryngology of Heidelberg University Hospital and underwent panendoscopy with lymph node removal. In general, disease- and progression-free survival, prognostic relevant risk factors, and treatment data were recorded and analyzed.</p><p><strong>Results: </strong>The mean age of patients with CUP was significantly higher at 65 ± 13.2 years than that of patients with LNC (41 ± 15.8 years; <i>P</i> = .000). The calculated cutoff value was 50 to 59 years for a 50% chance of CUP syndrome or other malignant neck mass. Alcohol and tobacco consumption were not found to be risk factors. Previous tumor diseases were diagnosed more frequently in patients with CUP than in patients with LNC (<i>P</i> = .045). The 5 year overall survival for patients with CUP was 77.0% and did not differ significantly between the other various tumor entities (<i>P</i> = .423).</p><p><strong>Conclusions: </strong>The consideration of patient-specific factors such as age or synchronous/asynchronous malignancies is crucial in the diagnostic decision-making process. In the age group of 50 to 59 years, there is ~50% probability of diagnosing CUP syndrome with unilateral painless neck swelling. A thorough clinical examination using panendoscopy with at least 1 unilateral tonsillectomy and biopsies from the base of the tongue is essential to detect a possible primarius early and improve the prognosis.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251337985"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Septic Thrombophlebitis of Multiple Dural Sinuses Extending to Bilateral Internal Jugular Veins due to Acute Sphenoid Sinusitis: A Case of Lemierre's Syndrome.","authors":"Asimakis D Asimakopoulos, Vincent Dunet, Antoine Reinhard","doi":"10.1177/01455613251341148","DOIUrl":"https://doi.org/10.1177/01455613251341148","url":null,"abstract":"<p><p>Lemierre's syndrome (LS) is a rare and potentially life-threatening condition characterized by septic thrombophlebitis within the head and neck region. The lack of a standardized definition in the literature contributes to its limited evidence base. LS presents with various clinical manifestations, often showing atypical features across different age groups. Early diagnosis of LS is challenging due to its nonspecific nature. Recent evidence highlights significant short- and long-term morbidity risks. Successful management requires a multidisciplinary approach and appropriate antibiotic therapy. While LS is commonly associated with oropharyngeal infections, it can also arise from non-oropharyngeal sources, complicating diagnosis and management. We present a case of LS secondary to acute isolated sphenoid sinusitis in an 86-year-old woman. Imaging revealed multiple metastatic septic thrombophlebitis, including bilateral cavernous, inferior petrosal, right transverse and sigmoid sinuses, and internal jugular veins. Blood cultures grew <i>Streptococcus intermedius</i>, and endoscopic sphenoidotomy identified a fungus ball, with cultures confirming <i>Streptococcus anginosus</i> and <i>Aspergillus fumigatus</i>. The patient demonstrated significant recovery with no complications at follow-up. This case illustrates a complex, multifocal pattern of septic thrombophlebitis, extending to multiple venous structures, highlighting the need for comprehensive imaging and a multidisciplinary approach in diagnosing and managing this rare complication. Early recognition of LS, even in the context of non-oropharyngeal infections, is crucial for optimal treatment and improved outcomes.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251341148"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Preoperative Systemic Inflammation Response Index in Surgically Treated Young Head and Neck Cancer Patients Under 40.","authors":"Pei-Yin Wu, Yao-Te Tsai, Yu-Tsai Lin, Hui-Ching Chuang, Chao-Hui Yang, Chih-Yen Chien, Fu-Min Fang, Tai-Lin Huang, Hui Lu, Ming-Hsien Tsai","doi":"10.1177/01455613251338940","DOIUrl":"https://doi.org/10.1177/01455613251338940","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the prognosis of young patients (≤40 years old) with head and neck squamous cell carcinoma (HNSCC), focusing on the preoperative Systemic Inflammation Response Index (SIRI).</p><p><strong>Methods: </strong>Between January 2007 and February 2017, 175 young patients with HNSCC (≤40 years old) who underwent radical surgery were retrospectively enrolled in this study. The patients were randomly divided into a training cohort (N = 131) and a validation cohort (N = 44). The SIRI is defined as the absolute neutrophil count (×10⁹/L) multiplied by the absolute monocyte count (×10⁹/L), divided by the absolute lymphocyte count (×10⁹/L) in peripheral blood, all measured within one week prior to radical surgery. Univariate and multivariate Cox regression analyses were conducted to identify variables associated with survival outcomes, which were then used to construct and evaluate a predictive nomogram.</p><p><strong>Results: </strong>In both the training and validation cohorts, patients were classified into low- and high-SIRI groups based on a cutoff value of 0.87, which was determined by receiver operating characteristic analysis. This SIRI cutoff effectively stratified patients into two distinct prognostic groups with significant survival differences. Multivariable Cox analysis identified the presence of lymphovascular invasion and the high preoperative SIRI as significant independent prognostic factors associated with poorer cancer-specific survival (CSS) in young patients with HNSCC. Using these variables, a predictive model for 5 year CSS was constructed and visualized as a nomogram. The model demonstrated strong predictive performance, with a <i>C</i>-index of 0.744 [95% CI (0.643-0.845)] in the training cohort and 0.839 [95% CI (0.740-0.938)] in the validation cohort.</p><p><strong>Conclusion: </strong>Data from preoperative SIRI assessment, coupled with the presence of pathological adverse features, serve as valuable references for risk stratification in young patients with HNSCC.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251338940"},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}