Ear, nose, & throat journal最新文献

{"title":"Low-Temperature Plasma Radiofrequency Ablation for Congenital Epiglottic Cysts.","authors":"Hao Cai, Jinjian Gao","doi":"10.1177/01455613241259368","DOIUrl":"10.1177/01455613241259368","url":null,"abstract":"<p><p><b>Objectives:</b> Congenital epiglottic cysts are rare disorders of the larynx with symptoms such as laryngeal stridor and inspiratory dyspnea and are life-threatening in severe cases. This study aimed to investigate the usefulness of low-temperature plasma radiofrequency ablation for congenital epiglottic cysts and provide a reference for clinicians to develop treatment options. <b>Methods:</b> The clinical data of children (n = 7, 4 males and 3 females) with congenital epiglottic cysts, who were admitted to the Second Affiliated Hospital of Wenzhou Medical University and Yuying Children's Hospital from March 2018 to March 2023, were analyzed retrospectively. Following preoperative examinations, all patients underwent low-temperature plasma radiofrequency ablation under general anesthesia, and the curative effect was evaluated. Following surgery, regular patient follow-up examinations were conducted to monitor recurrence. <b>Results:</b> The age at the time of operation ranged from 1 day to 99 days, with an average of 37.57 ± 35.01 days. The surgical procedure was successfully completed in all the children; dyspnea disappeared and no surgical complications were observed. In addition, during the postoperative follow-up period of 6 months to 5 years, recurrence was not observed. <b>Conclusions:</b> Low-temperature plasma radiofrequency ablation is a safe and effective procedure for treating congenital epiglottic cysts and deserves clinical application and promotion.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"351-354"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on the Short-Term Recurrence of Low-Grade Fibromyxoid Sarcoma in the Maxillary Sinus.","authors":"Dan Zhao, Jian Dai, Yu Hu, Tao Wang","doi":"10.1177/01455613241276673","DOIUrl":"10.1177/01455613241276673","url":null,"abstract":"<p><p>Low-grade fibromyxoid sarcoma (LGFMS) represents an exceptionally rare soft-tissue tumor, challenging to diagnose, and notorious for relentless recurrence and proliferation postsurgical resection. Primary symptoms of LGFMS include nasal congestion and rhinorrhea, accompanied by cheek numbness and distension. In this article, we report the diagnosis and treatment of a case of low-grade LGFMS originating in the maxillary sinus (MS). A 64-year-old male diagnosed with LGFMS of the left MS, undergoing 3 surgeries over a 1-year period with subsequent local recurrence. Following inconclusive postoperative pathology after the initial surgery, the patient experienced recurrence 2 months postsurgery, necessitating a second operation, which confirmed the LGFMS diagnosis pathologically. Radiation therapy commenced 1 month after the second surgery; however, recurrence transpired 6 months later, leading to a third operation. Subsequently, recurrence occurred again 8 months post third surgery, with the patient currently undergoing targeted therapy. This case underscores the distinct characteristics and therapeutic challenges inherent in LGFMS through the narrative of diagnosis and progression of LGFMS originating in the MS.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"346-350"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Nasal Nitric Oxide to Compare Endoscopic Sinus Surgery Versus Dupilumab: An Exploratory Real-World Comparison.","authors":"Daniel J Lee, Giovanni Paoletti, Gaia Giulietti, Elysia Grose, Roberto Pinto, Enrico Heffler, John M Lee","doi":"10.1177/01455613251343737","DOIUrl":"https://doi.org/10.1177/01455613251343737","url":null,"abstract":"<p><strong>Objective: </strong>To compare the outcomes of endoscopic sinus surgery (ESS) and dupilumab using nasal nitric oxide (nNO) as a biomarker of mucosal health, Lund-Kennedy endoscopy score (LKES), and Sino-Nasal Outcome Test-22 (SNOT-22).</p><p><strong>Methods: </strong>A prospective observational cohort of chronic rhinosinusitis with nasal polyposis (CRSwNP) patients who underwent ESS followed by standard postoperative therapy was compared with another prospective cohort of CRSwNP patients who received dupilumab. In addition to baseline characteristics, nNO production, LKES, and SNOT-22 levels were compared between the 2 cohorts at the 1st month and 6th month posttreatment.</p><p><strong>Results: </strong>A total of 28 and 37 patients were included in the ESS cohort and the dupilumab group, respectively. At the 1stmonth and 6th month posttreatment, nNO levels were comparable between 2 groups. Compared to baseline, the ESS cohort showed increased nNO levels at 1st month posttreatment, while the dupilumab group did not. At the 6th month posttreatment, both groups exhibited a significant increase in nNO levels. Similar trend was observed in LKES. SNOT-22 decreased at the 1st month and 6th month posttreatment compared with that in baseline.</p><p><strong>Conclusion: </strong>ESS and dupilumab confer comparable benefits in terms of nNO changes, symptoms, and endoscopy findings at the 6th month posttreatment. ESS may result in more rapid improvement in the outcomes than in dupilumab as evidenced by the 1 month posttreatment values.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251343737"},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retropharyngeal Abscess Secondary to Rare Posttraumatic Spondylodiscitis: An Unusual Presentation.","authors":"Chiraz Halwani, Sonia Esseghaier, Malek Khaskhoussi, Askri Haythem, Sana Boughariou, Hedi Gharsallah","doi":"10.1177/01455613251345397","DOIUrl":"https://doi.org/10.1177/01455613251345397","url":null,"abstract":"<p><strong>Introduction: </strong>Posttraumatic spondylodiscitis is an uncommon but serious complication of spinal trauma. It may lead to severe neurological impairment and systemic infection. Retropharyngeal abscess (RPA), typically associated with upper respiratory infections, is rarely reported as a complication of nontuberculous spondylodiscitis, especially in the context of cervical trauma. This rare association poses a dual threat: airway obstruction and spinal cord compression. Our work aimed to report a rare case of posttraumatic, nontuberculous cervical spondylodiscitis complicated by an RPA, leading to both respiratory and neurological compromise, and to highlight the importance of early multidisciplinary management.</p><p><strong>Observation: </strong>We present the case of a 45- year-old male with posttraumatic dorsal and cervical spondylitis following a road traffic accident. He developed progressive paraplegia and respiratory distress. Imaging revealed multilevel vertebral involvement with spinal cord compression and an RPA. The first transoral drainage was ineffective, and the recurrence within 48 hours necessitated a second external surgical approach. Cultures identified methicillin-resistant <i>Staphylococcus aureus</i> and <i>Klebsiella pneumoniae</i>. Broad-spectrum antibiotics and intensive care management led to gradual improvement.</p><p><strong>Conclusion: </strong>This case underlines the complexity and severity of posttraumatic spondylodiscitis with RPA. Prompt diagnosis and a multidisciplinary therapeutic strategy are vital to prevent life-threatening complications and improve patient outcomes.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251345397"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicoradiological Evaluation of Cholesteatoma: Integrating Clinical, CT, and MRI Diagnostics.","authors":"Tarek Mohamed M Mansour, Mahmoud Mohamed El Bahrawy, Mohamed Mohamed Elmoursy, Ahmed Elrahman Mohamed Azzam","doi":"10.1177/01455613251343790","DOIUrl":"https://doi.org/10.1177/01455613251343790","url":null,"abstract":"<p><strong>Objectives: </strong>The common chronic disorder, otitis media (COM), can lead to cholesteatoma, a destructive lesion of the middle ear that could potentially have major consequences. Correct diagnosis at an early stage is crucial for effective management. In this study, histopathology is used as the gold standard to compare how well a clinicoradiological method that uses clinical observations, high-resolution computed tomography (HRCT), and echo-planar imaging diffusion-weighted magnetic resonance imaging (EPI-DWI) can diagnose cholesteatoma.</p><p><strong>Methods: </strong>A prospective diagnostic accuracy study was conducted on 230 patients aged 15 to 50 years with COM and clinically-suspected cholesteatoma. All patients underwent clinical evaluation (history, otoscopy, and audiometry) followed by HRCT and EPI-DWI imaging. Imaging findings were interpreted independently by radiologists blinded to clinical and histopathological results. Surgical exploration and histopathological confirmation were performed in all cases.</p><p><strong>Results: </strong>Of the 230 patients, histopathology confirmed cholesteatoma in 110 cases (47.8%). Diffusion-weighted magnetic resonance imaging (DW-MRI) demonstrated superior sensitivity (92.7%) and specificity (89.4%) compared with HRCT (sensitivity: 75.5%; specificity: 70.2%). The clinicoradiological approach combining clinical assessment with EPI-DWI and HRCT improved diagnostic accuracy, achieving a sensitivity of 95.5%, specificity of 90.7%, positive predictive value of 93.2%, and negative predictive value of 94.3%. Receiver operating characteristic analysis revealed an area under the curve of 0.96 for DW-MRI and 0.88 for the clinicoradiological approach. Cohen's kappa showed an excellent agreement between the clinicoradiological assessment and histopathology (κ = .85).</p><p><strong>Conclusions: </strong>The integration of clinical findings with EPI-DWI and HRCT significantly enhances the diagnostic accuracy for cholesteatoma, making the clinicoradiological approach a valuable tool in the evaluation of patients with COM. EPI-DWI remains the preferred imaging modality for cholesteatoma diagnosis, while HRCT provides complementary information on middle ear anatomy and bone erosion.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251343790"},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Postoperative Care Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis.","authors":"W Jared Martin, Lauren M Cook, Yasine Mirmozaffari, Ezer H Benaim, Jackson R Vuncannon, Cristine Klatt-Cromwell, Brent A Senior, Charles S Ebert","doi":"10.1177/01455613251342957","DOIUrl":"https://doi.org/10.1177/01455613251342957","url":null,"abstract":"<p><strong>Objectives: </strong>This study reviews current postoperative care recommendations following endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS), with the goal of optimizing recovery, minimizing complications, and reducing the risk of disease recurrence.</p><p><strong>Methods: </strong>A comprehensive literature review was conducted to identify studies on postoperative care following ESS for CRS. Findings were synthesized to develop evidence-based recommendations for optimal postoperative management.</p><p><strong>Results: </strong>Postoperative care following ESS for CRS requires a multifaceted approach. Pain management should prioritize acetaminophen and nonsteroidal anti-inflammatory drugs, with opioids reserved for severe pain. Nasal irrigation, topical corticosteroids, and debridement are recommended for all patients. Nasal packing and drug-eluting devices may offer additional benefits, but are not universally required. The use of antibiotics and oral corticosteroids should be selective and guided by individual patient factors and risk profiles.</p><p><strong>Discussion: </strong>While general recommendations are made, patient-specific factors such as comorbidities, financial constraints, and adherence to care must be considered. Further evaluation of these factors is essential to establish a more comprehensive and individualized standard of care for postoperative management.</p><p><strong>Conclusions: </strong>Effective postoperative care following ESS for CRS should be individualized, multifaceted, and focused on improving recovery, minimizing complications, and ensuring the best possible patient outcomes.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251342957"},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated Palatal Perforation Secondary to Diffuse Large B-Cell Lymphoma: A Diagnostic Challenge.","authors":"Yasser ALGhabra, Mohammad Hamdi, Mudar Ismael, Abdulrahman Shaker, Adham Bader Aldeen Mohsen","doi":"10.1177/01455613251343739","DOIUrl":"https://doi.org/10.1177/01455613251343739","url":null,"abstract":"<p><p>Palatal perforation, a diagnostically complex condition, arises from diverse etiologies including neoplasms, infections, or inflammatory disorders. Patients often experience dysphagia, dysarthria, and social distress due to nasal regurgitation. We report a 22 year-old cachectic woman with isolated palatal perforation secondary to diffuse large B-cell lymphoma (DLBCL). She presented with a 2-month history of a painless, progressive midline ulcer unresponsive to antibiotics, culminating in a 2 cm perforation. Biopsies revealed necrotic tissue, fungal elements, and atypical lymphocytes; immunohistochemistry confirmed DLBCL (CD20+, CD3-). Imaging and labs excluded systemic involvement, infections (HIV, syphilis), and autoimmune conditions. Despite lacking classic B-symptoms, elevated lactate dehydrogenase (392 U/L) and iron-deficiency anemia suggested malignancy. This case highlights the diagnostic challenge of DLBCL mimicking benign lesions and underscores the need for multidisciplinary evaluation integrating histopathology and immunohistochemistry. Early diagnosis is critical, as R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy can improve outcomes. Clinicians should consider lymphoma in persistent palatal lesions, even without systemic signs. This report emphasizes the role of timely, targeted therapy in otolaryngologic manifestations of systemic malignancies.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251343739"},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cohort Characteristics of Pediatric Candidates for Cochlear Implantation With Inner Ear Malformations: A Multicenter Retrospective Study.","authors":"Hejie Li, Wenting Yu, Wei Tang, Ting Li, Xuan Yu, Shimin Zong, Hongjun Xiao","doi":"10.1177/01455613251342846","DOIUrl":"https://doi.org/10.1177/01455613251342846","url":null,"abstract":"<p><strong>Objective: </strong>To investigate comorbidities and severity correlations among inner ear malformations (IEMs) classifications and analyze subtype characteristics to optimize preoperative evaluation and cochlear implantation (CI) strategies.</p><p><strong>Methods: </strong>Retrospective multicenter data from Hubei Province were analyzed for 336 children with IEMs who received unilateral CI (2012-2020). IEMs were classified and graded using Sennaroğlu and Adibelli criteria, and data visualization tools were used to assess subtypes, comorbidities, and severity correlations.</p><p><strong>Results: </strong>Among pediatric candidates for CI with IEMs, isolated enlarged vestibular aqueduct, isolated incomplete partition type II, and multiple malformations were the 3 most common subtypes, accounting for 80.7% of cases. Vestibular aqueduct malformation (VAM) primarily occurred as an isolated condition, whereas internal auditory canal malformation (IACM), cochlear nerve malformation (CNM), cochlear malformation (CM), and vestibular and semicircular canal malformation (VSCM) tended to coexist, exhibiting significant co-occurrence patterns. Severity analysis revealed a positive correlation between the severity of IACM and CNM (<i>r</i> = .13, <i>P</i> = .015), as well as between CM and VSCM (<i>r</i> = .17, <i>P</i> < .001). Additionally, VAM severity was significantly negatively correlated with the severity of IACM, CNM, CM, and VSCM (<i>r</i> = -.39, -.21, -.38, and -.30, respectively; <i>P</i> < .001).</p><p><strong>Conclusion: </strong>This study elucidated a detailed analysis of the subtype characteristics and comorbid relationships of IEMs in pediatric candidates for CI. Furthermore, it identified significant correlations between the severity levels of different malformation types. These insights contribute to refining preoperative evaluation protocols and tailoring treatment strategies for CI candidates.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251342846"},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papillary Thyroid Microcarcinoma Revealed by Contralateral Cystic Metastasis Mimicking a Branchial Cleft Cyst.","authors":"Chiraz Halwani, Anas Ammar, Salma Elbessi, Karima Tlili, Khemaies Akkari, Sonia Esseghaier","doi":"10.1177/01455613251343725","DOIUrl":"https://doi.org/10.1177/01455613251343725","url":null,"abstract":"<p><strong>Introduction: </strong>Papillary thyroid microcarcinomas (PTMC) can exhibit invasive behavior with lymph node metastasis despite their small size. In some cases, they may present as cystic lymph node metastases, clinically and radiologically mimicking benign lesions such as branchial cleft cysts. These misleading presentations may delay the diagnosis of an underlying thyroid malignancy. We report a rare and atypical presentation of PTMC as a large contralateral cystic lymph node metastasis initially diagnosed as a branchial cleft cyst, highlighting the need to consider metastatic thyroid carcinoma in the differential diagnosis of lateral neck cysts.</p><p><strong>Observation: </strong>A 51-year-old woman presented with a left lateral cervical mass diagnosed as a second branchial cleft cyst. Surgical excision and histology revealed a metastatic lymph node from papillary thyroid carcinoma. Subsequent workup identified a 4 mm PTMC in the right thyroid lobe. The patient underwent total thyroidectomy, lymph node dissection, and radioactive iodine therapy.</p><p><strong>Conclusion: </strong>PTMC may behave aggressively and present with misleading cystic nodal metastases. Clinicians should include metastatic papillary thyroid carcinoma in the differential diagnosis of isolated cystic neck masses, even in the absence of an identifiable thyroid lesion on initial imaging.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251343725"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Anterior Epistaxis in Children With Allergic Rhinitis and Non-Allergic Rhinitis: Clinical Features.","authors":"Linyan Tao, Zhengcai Lou","doi":"10.1177/01455613251342916","DOIUrl":"https://doi.org/10.1177/01455613251342916","url":null,"abstract":"<p><strong>Objective: </strong>This study described the endoscopic characteristics of recurrent anterior epistaxis (RAE) with and without allergic rhinitis (AR), and the outcomes of treatment with mupirocin ointment.</p><p><strong>Material and methods: </strong>Children with RAE were examined using nasal endoscopy, serum specific immunoglobulin E antibodies, and skin-prick test. The children were divided into AR (RAE with AR) and non-AR (RAE without AR) groups. All children received mupirocin ointment topically twice daily for 4 weeks. Recurrent epistaxis and epistaxis severity scores were compared at 2, 4, and 12 weeks of follow-up.</p><p><strong>Results: </strong>A total of 326 patients with 432 nostrils with RAE were included; 76.4% of patients had the bad habit of frequent nose-picking or rubbing. Of the 178 nostrils in the AR group, diffuse telangiectasia was found in 89.3%, scattered telangiectasia in 8.4%, and mucosal ulceration in 2.3%. Of the 254 nostrils in the non-AR group, the endoscopic findings of the anterior septum in the bleeding nostrils included mucosal ulceration in 77.6%, scattered telangiectasia in 17.7%, isolated punctate telangiectasias in 3.1%, and diffuse telangiectasia in 1.6%. In addition, the prevalence of mucosal crusts in the non-AR group was significantly higher than in the AR group (76.8% vs 20.8%), whereas the prevalence of severe hypertrophic inferior turbinates or nasal secretion was significantly higher in the AR group. The prevalence of recurrent epistaxis was significantly higher in the AR group than in the non-AR group at 2 (71.3% vs 57.7%), 4 (65.7% vs 37.8%), and 12 (78.1% vs 43.5%) weeks post-treatment.</p><p><strong>Conclusions: </strong>AR was common in children with RAE, with prominent diffuse telangiectasia evident by endoscopy in most, while most non-AR RAE children had mucosal ulceration or scattered telangiectasia. Compared with outcomes in non-AR RAE children, the efficacy of mupirocin ointment in the treatment of RAE with AR was not satisfactory.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251342916"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}