Ear, nose, & throat journal最新文献_第2页

Re: Martínez-Herrera et al Titled "Quality of Life and Functionality of Head and Neck Cancer Patients Are Diminished as a Function of Sarcopenia and Obesity". 回复：Martínez-Herrera等人题为“头颈癌患者的生活质量和功能随着肌肉减少和肥胖而下降”。

Ear, nose, & throat journal Pub Date : 2025-07-23 DOI: 10.1177/01455613251360122

Efsun Somay, Erkan Topkan, Ugur Selek

引用次数: 0

Diagnostic and Therapeutic Challenges in Limited GPA With Nasal Synechiae: A Case Report and Literature Review. 局限性GPA伴鼻粘连的诊断和治疗挑战：1例报告和文献综述。

Ear, nose, & throat journal Pub Date : 2025-07-22 DOI: 10.1177/01455613251358076

Abdullah S AlDughaither, Abdulmohsin S Aldossari, Ali M Alsudays, Sultan Mogren Almogairen, Surayie H Al Dousary

{"title":"Diagnostic and Therapeutic Challenges in Limited GPA With Nasal Synechiae: A Case Report and Literature Review.","authors":"Abdullah S AlDughaither, Abdulmohsin S Aldossari, Ali M Alsudays, Sultan Mogren Almogairen, Surayie H Al Dousary","doi":"10.1177/01455613251358076","DOIUrl":"https://doi.org/10.1177/01455613251358076","url":null,"abstract":"Background: Usually linked with anti-neutrophil cytoplasmic antibodies (ANCA), granulomatosis with polyangiitis (GPA) is an uncommon systemic necrotizing vasculitis. Although GPA sometimes shows multiorgan involvement, the confined phenotype-mostly affecting the upper respiratory tract-can provide major diagnostic and therapeutic difficulties. Though nonsystemic, limited GPA might resemble chronic rhinosinusitis and is at risk for progression or consequences.Case: Following COVID-19 immunization and past COVID-19 infection, we describe a case of a 23 year-old girl presenting with persistent nasal obstruction, headache, severe facial pain, crustation, nose bleeding, and anosmia for 1.5 years. Examination revealed bilateral nasal ulceration and crusting; evaluation also indicated mucosal thickening and positive c-ANCA with high proteinase 3 titers. Without granulomatous characteristics, histopathology revealed persistent inflammation and inflammatory nasal polyps. The patient was first managed with methotrexate; therapy was upgraded to rituximab (RTX) due to ongoing symptoms. After RTX induction, the patient achieved clinical remission, with resolution of nasal symptoms and normalization of inflammatory markers. She stayed in remission at the follow-up.Conclusion: This case highlights the diagnostic complexity and therapeutic challenges associated with limited GPA, particularly when ear, nose, and throat symptoms predominate without systemic involvement. Key to reaching remission is early rheumatologic referral, interdisciplinary treatment, and rapid escalation to biologic therapy. RTX is a good and well-tolerated choice in refractory restricted GPA; yet more studies are warranted.","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251358076"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retropharyngeal Ectopic Papillary Thyroid Carcinoma Coexisting with Orthotopic Goiter: A Rare Case Report. 咽后异位甲状腺乳头状癌合并正位甲状腺肿一例罕见报告。

Ear, nose, & throat journal Pub Date : 2025-07-22 DOI: 10.1177/01455613251359427

Xiaxia Li, Guokang Fan, Zhewei Lou

{"title":"Retropharyngeal Ectopic Papillary Thyroid Carcinoma Coexisting with Orthotopic Goiter: A Rare Case Report.","authors":"Xiaxia Li, Guokang Fan, Zhewei Lou","doi":"10.1177/01455613251359427","DOIUrl":"https://doi.org/10.1177/01455613251359427","url":null,"abstract":"Objective: Ectopic thyroid carcinoma is rare. We present an exceptionally rare case of primary retropharyngeal ectopic papillary thyroid carcinoma (PTC) coexisting with an orthotopic thyroid goiter, aiming to enhance clinical awareness of this condition and to emphasize the importance of comprehensive management of both the ectopic lesion and the orthotopic thyroid.Methods: Case report and literature review.Results: A 29-year-old male with a 3-year history of pharyngeal foreign body sensation underwent laryngoscopy and noncontrast CT/MRI, revealing a 2.0 × 3.5 cm left retropharyngeal mass. The mass was confirmed as papillary carcinoma via transoral excision. Postoperative contrast-enhanced CT identified metastatic-level VI lymphadenopathy, prompting total thyroidectomy with central neck dissection. Histopathology verified ectopic PTC with central node metastasis (1/20 nodes). Orthotopic thyroid exhibited nodular goiter without malignancy. No recurrence was observed during 36 months of follow-up.Conclusions: This case highlights retropharyngeal ectopic PTC's diagnostic complexity in a patient with orthotopic thyroid gland. Management of ectopic thyroid carcinoma may be guided by thyroid carcinoma guidelines, given its rarity. Total thyroidectomy is recommended to exclude concurrent thyroid malignancy and enable thyroglobulin-based surveillance.","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251359427"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Unusually Huge Keloid Complicating a Unilateral Otoplasty. 单侧耳成形术并发异常巨大瘢痕疙瘩。

Ear, nose, & throat journal Pub Date : 2025-07-20 DOI: 10.1177/01455613251358656

Adel Azar, Ahmad Alkheder, Diana Mohammad, Ahmad Mustafa

{"title":"An Unusually Huge Keloid Complicating a Unilateral Otoplasty.","authors":"Adel Azar, Ahmad Alkheder, Diana Mohammad, Ahmad Mustafa","doi":"10.1177/01455613251358656","DOIUrl":"https://doi.org/10.1177/01455613251358656","url":null,"abstract":"Giant recurrent auricular keloids, particularly those complicated by donor-site involvement, present significant therapeutic challenges due to aggressive fibroblast biology and high recurrence rates. We report a complex case of a 15-year-old female who developed a massive recurrent auricular keloid with associated abdominal donor-site keloid following otoplasty and subsequent skin grafting. Initial otoplasty at age 10 was complicated by keloid formation, requiring excision and abdominal full-thickness grafting. By age 15, she presented with a recurrent auricular keloid causing auricular deformity, tragus distortion, and external auditory canal obstruction, alongside a donor-site keloid. Management involved the radical excision of both keloids. To minimize tension-induced recurrence, the auricular wound underwent deliberate secondary intention healing, while the abdominal site was closed primarily under minimal tension. Adjuvant therapy comprised 6 weekly intralesional interferon-gamma (IFN-γ) injections (1 million units auricle; 0.5 million units abdomen). This multimodal approach leveraged IFN-γ's antifibrotic properties, including ferroptosis induction in keloid fibroblasts. At 1-year follow-up, both sites exhibited sustained remission with good fibrosis and acceptable cosmesis without recurrence. This case demonstrates that tension-free excision with secondary intention healing, combined with intralesional IFN-γ, offers a promising strategy for managing complex pediatric keloids where conventional therapies carry substantial limitations. The protocol effectively addresses both biological recurrence drivers and psychosocial burdens inherent to disfiguring scars.","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251358656"},"PeriodicalIF":0.0,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19-Associated Phlegmonous Intraparotid Lymphadenitis Presenting With Cervical Cellulitis and Airway Compromise. 以宫颈蜂窝织炎和气道损害为表现的covid -19相关痰性腮腺内淋巴结炎

Ear, nose, & throat journal Pub Date : 2025-07-19 DOI: 10.1177/01455613251359424

Asimakis D Asimakopoulos, Andrea Avagnina, Salim Bouayed

引用次数: 0

Pseudo-Continuous Arterial Spin Labeling Magnetic Resonance Imaging in Diagnosis of Glomus Tympanicum. 伪连续动脉自旋标记磁共振成像诊断鼓室球。

Ear, nose, & throat journal Pub Date : 2025-07-17 DOI: 10.1177/01455613251360589

Hiroshi Sakaida, Ryota Kogue, Maki Umino, Fumine Tanaka, Masayuki Maeda

引用次数: 0

A Report of Two Cases of Planum Sphenoidale Injuries With Cerebrospinal Rhinorrhea Following Office Balloon Dilation of the Sphenoid Ostium: Lessons Learned. 办公室蝶骨口球囊扩张术致蝶平面损伤并发脑脊液鼻漏2例：经验教训。

Ear, nose, & throat journal Pub Date : 2025-07-17 DOI: 10.1177/01455613251353643

Austin R Swisher, Simon Beatty, Amar Miglani, Devyani Lal

{"title":"A Report of Two Cases of Planum Sphenoidale Injuries With Cerebrospinal Rhinorrhea Following Office Balloon Dilation of the Sphenoid Ostium: Lessons Learned.","authors":"Austin R Swisher, Simon Beatty, Amar Miglani, Devyani Lal","doi":"10.1177/01455613251353643","DOIUrl":"https://doi.org/10.1177/01455613251353643","url":null,"abstract":"Balloon-assisted dilation (BAD) of paranasal sinus ostia is a Food and Drug Administration (FDA)-approved minimally-invasive procedure used to treat medically refractory chronic rhinosinusitis. Several large cohort studies have reported relatively-low complication rates with BAD. Thus, users of this technology may perceive this to be a safer alternative to formal dissection of the frontal and sphenoid sinus and perform these as office-based procedures. Here, we present 2 patients who underwent BAD of the sphenoid sinus and developed cerebrospinal fluid leak (CSF) leaks with pneumocephalus. Both patients had thinning of the planum sphenoidale in generously-pneumatized sphenoid sinuses. Although BAD is considered safe, review of the current literature demonstrates that serious complications can occur. These case reports demonstrate the potential for skull base injury, particularly in hyper-pneumatized sphenoid sinuses with dehiscent bone. Preoperative anatomic evaluation is crucial to identify at-risk patients. During BAD, trauma to critical structures may cause CSF leak and result in pneumocephalus. This knowledge is important for improving surgical decision-making and patient counseling.Level of Evidence: III.","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251353643"},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Driven from Passion to Compulsion: The Soft Science and Philosophy Behind Authorship Misconduct. 从激情到强迫：作者不当行为背后的软科学和哲学。

Ear, nose, & throat journal Pub Date : 2025-07-17 DOI: 10.1177/01455613251360112

Mainak Dutta

引用次数: 0

Vocal Cord Paralysis Secondary to Diffuse Idiopathic Skeletal Hyperostosis: A Case Report and Literature Review. 声带麻痹继发于弥漫性特发性骨骼肥厚：1例报告及文献复习。

Ear, nose, & throat journal Pub Date : 2025-07-17 DOI: 10.1177/01455613251360123

Xin-Tian He, Hsin-Chien Chen

引用次数: 0

Post-Auricular Teratoma Masquerading as a Branchial Cleft Cyst. 伪装成鳃裂囊肿的耳后畸胎瘤。

Ear, nose, & throat journal Pub Date : 2025-07-16 DOI: 10.1177/01455613251355945

Elif Gozgec, Hayri Ogul

引用次数: 0