Ear, nose, & throat journal最新文献

{"title":"PRP and Diced Cartilage-Enhanced Fascia Lata: A Composite Graft for Septal Perforation Repair.","authors":"Deniz Hanci, Öykü İzel Onaran, Hüseyin Altun, Berke Berat Bozer, Berk Gürpınar, Mert Obuz, Merih Cem Baş, Veysel Topalan, Yiğit Tolga, Tuğçe Gültepe Zorlu, Yavuz Uyar","doi":"10.1177/01455613251380096","DOIUrl":"https://doi.org/10.1177/01455613251380096","url":null,"abstract":"<p><strong>Objective: </strong>Nasal septal perforation (NSP) is characterized by defects in the mucosal, cartilaginous, and bony structures of the septum, most commonly resulting from septoplasty. Spontaneous healing of NSPs is rare, necessitating surgical intervention once the condition stabilizes. Numerous techniques have been developed for NSP repair. This study presents a novel technique combining fascia lata grafts, platelet-rich plasma (PRP), and diced septal cartilage harvested from the patient's remaining deviated nasal septum for the repair of medium-sized NSPs.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 32 patients who underwent NSP repair between July 2022 and July 2023. The repair utilized fascia lata, PRP derived from venous blood, and diced cartilage from residual septal cartilage. The procedure involved an open rhinoplasty approach for graft placement, followed by stabilization using endoscopic techniques.</p><p><strong>Results: </strong>The mean horizontal and vertical diameters of the septal perforations were 12.06 ± 2.87 mm and 13.12 ± 2.44 mm, respectively. All patients had medium-sized perforations (0.5-2 cm). The mean follow-up period was 12.03 ± 1.11 months. Complete closure was achieved in 28 of 32 cases (87.5%). The cohort included 18 males (56.3%) and 14 females (43.8%), with a mean age of 35.47 ± 5.31 years (range: 25-45). Ten patients (31.3%) were smokers, among whom 4 experienced incomplete closure. Smoking was not significantly associated with repair failure (<i>P</i> = .06).</p><p><strong>Conclusion: </strong>This novel technique combining fascia lata, PRP, and diced septal cartilage offers a reliable and effective approach for the repair of medium-sized NSPs.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251380096"},"PeriodicalIF":0.7,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Tinnitus and Dizziness and Their Association With Recurrent and Chronic Headache in Adults.","authors":"Mehdi Rezvani Amin, Fariba Shahraki-Sanavi, Mahmood Rezvani Amin, Alireza Salar, Alireza Ansari Moghaddam, Mahdi Mohammadi, Zahra Sarhadi","doi":"10.1177/01455613251382380","DOIUrl":"https://doi.org/10.1177/01455613251382380","url":null,"abstract":"<p><strong>Background: </strong>Tinnitus is the most common auditory disorder and can profoundly affect quality of life. It can contribute to various types of headaches, including chronic and recurrent forms. Dizziness is also among the most common complaints in medicine, affecting 15% to 35% of the general population at some point in their lives. Experiencing headache and dizziness simultaneously is often alarming, yet this combination can result from multiple causes ranging from dehydration to anxiety. This study aimed to examine the impact of tinnitus and dizziness on chronic and recurrent headaches among adults residing in Zahedan, southeastern Iran.</p><p><strong>Methods and materials: </strong>This study utilized baseline data from the Zahedan Adult Cohort Study. Participants were enrolled according to the cohort's inclusion criteria, while individuals with severe physical or mental disabilities or those unable to complete the questionnaire were excluded. Data were analyzed using descriptive statistics (frequency, mean, standard deviation, percentage) and logistic regression in SPSS 22. A significance level of <i>P</i> < .05 was applied. Logistic regression models were applied to assess associations between tinnitus, dizziness, and headache types, adjusting for potential confounders.</p><p><strong>Results: </strong>The participants had a mean age of 50.44 ± 9.18 years. The mean age at onset of chronic headache was 37.43 ± 11.90 years. The prevalence of chronic and recurrent headaches was 5.2% and 36.2%, respectively. Women had a significantly higher likelihood of developing chronic headaches compared with men (odds ratio [OR] = 3.2, 95% confidence interval [CI]: 2.5-4.0). Recurrent headaches were more prevalent in women (OR = 2.5, 95% CI: 2.3-2.7). Additionally, hypertension, head trauma, and epilepsy were associated with increased risks of both chronic and recurrent headaches.</p><p><strong>Conclusion: </strong>Chronic and recurrent headaches were influenced by demographic factors, socio-economic status, and medical conditions such as hypertension, and head trauma. Importantly, both tinnitus and dizziness significantly increased the odds of these headaches. Social determinants, neurological comorbidities, and vestibular dysfunction appear to play key roles. These findings underscore the need for integrated otolaryngological and neurological care.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251382380"},"PeriodicalIF":0.7,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Allergic Rhinitis, Asthma, and Laryngopharyngeal Reflux Disease: A Systematic Review.","authors":"Baraa Ibrahim Awad, Laila Salah Aldokhail, Enar Mohammed Alotaibi, Hatem Mohammed Asiri, Yazeed Abdullah Asery, Nawaf Khalid Nahhas, Mohammed Halawani","doi":"10.1177/01455613251378726","DOIUrl":"https://doi.org/10.1177/01455613251378726","url":null,"abstract":"<p><strong>Background: </strong>Laryngopharyngeal reflux (LPR), allergic rhinitis (AR), and asthma are common airway disorders that often coexist, suggesting shared inflammatory mechanisms. LPR involves gastric reflux into the laryngopharynx, while AR and asthma are linked by the \"united airway\" hypothesis. Evidence indicates LPR may contribute to AR and asthma exacerbation, yet their interactions remain unclear. Understanding their interaction may enhance clinical outcomes.</p><p><strong>Objective: </strong>This systematic review aimed to evaluate the associations between LPR, AR, and asthma by analyzing studies that examined these conditions in various patient populations.</p><p><strong>Methodology: </strong>A comprehensive search of electronic databases, including PubMed, Scopus, and Google Scholar, was conducted for studies published up until 2024. Eligible studies were selected based on predefined inclusion criteria, and data on the prevalence, diagnostic methods, and associations between LPR, AR, and asthma were extracted. This systematic review was conducted and registered in PROSPERO (CRD42024588367). Statistical analysis was performed to determine the strength of the associations between these conditions.</p><p><strong>Results: </strong>The review identified significant associations between LPR and both AR and asthma. Multiple studies confirmed a positive correlation between LPR and AR, with worse AR symptoms observed in patients with more severe LPR. Additionally, a strong association between LPR and asthma was observed, particularly in patients with poorly-controlled asthma. The analysis also revealed a robust relationship between AR and asthma, consistent with the \"united airway\" hypothesis, which posits that the upper and lower airways share common inflammatory pathways. These findings suggest that the coexistence of these conditions may exacerbate symptoms and complicate management.</p><p><strong>Conclusion: </strong>This systematic review highlights the significant associations between LPR, AR, and asthma, emphasizing the importance of recognizing and addressing these comorbidities in clinical practice. The findings suggest that managing 1 condition may have a beneficial effect on the others, supporting a multidisciplinary approach to diagnosis and treatment.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251378726"},"PeriodicalIF":0.7,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late Recurrence/Metastasis of Acinic Cell Carcinoma After 10 Years of Resection: A Case Series and Literature Review.","authors":"Caroline E Boyle, Tieying Hou","doi":"10.1177/01455613251347174","DOIUrl":"https://doi.org/10.1177/01455613251347174","url":null,"abstract":"<p><strong>Background: </strong>Acinic cell carcinoma (AciCC) is a relatively rare malignancy of the salivary glands, predominantly affecting the parotid gland. Recent studies report that the local recurrence rate for AciCC ranges from 5% to 17%, while metastasis occurs in 2% to 12% of cases. Most recurrences or metastases are observed within the first 5 years following initial therapy. However, late recurrences or metastases occurring more than 10 years have been reported in rare cases.</p><p><strong>Methods: </strong>This study presents 13 cases of AciCC in which patients experienced recurrence or metastasis 10 to 45 years after initial treatment. The case series includes 6 patients identified from our database and 7 cases from a literature review.</p><p><strong>Results: </strong>In this small series, late recurrence or metastasis appeared more common in female patients. Four patients experienced recurrence confined to the tumor bed, with or without regional lymph node involvement. Seven patients developed distant metastases, while 2 experienced both local and distant diseases. The lungs, bones, and skin were the most common sites of distant metastases. Management predominantly involved surgical resection of the recurrence, often followed by radiation therapy. Two patients also received chemotherapy for distant metastases. Follow-up data were available for 11 patients: 2 succumbed to the disease, 1 died of an unrelated condition, and 8 remained alive.</p><p><strong>Conclusions: </strong>Diagnosing late-onset recurrence or metastasis of AciCC poses a unique challenge, as the primary tumor may have occurred decades earlier. Further research is needed to deepen our understanding of the clinical course and adjust clinical follow-up strategy.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251347174"},"PeriodicalIF":0.7,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Hyponatremia in Patients With Nasopharyngeal Cancer on Concurrent Chemoradiotherapy.","authors":"Peesit Leelasawatsuk, Usaporn Prapaisit, Theepat Wongkittithaworn, Yuvatiya Plodpai","doi":"10.1177/01455613251377558","DOIUrl":"https://doi.org/10.1177/01455613251377558","url":null,"abstract":"<p><strong>Objective: </strong>Hyponatremia occurs in patients with nasopharyngeal cancer (NPC) on chemoradiotherapy and causes prolonged hospitalization, low quality of life, and increased mortality. This study aimed to determine the associated factors of hyponatremia in patients with NPC on chemoradiotherapy and investigate changes in hyponatremic events over time.</p><p><strong>Methods: </strong>We retrospectively reviewed patients with NPC who underwent complete concurrent chemoradiotherapy between 2014 and 2024. Hyponatremia was defined as serum sodium levels <130 mmol/L. The median follow-up time was reported in person-months (pm); the incidence rate was defined as the number of events per 1000 pm. The Poisson regression model was used to estimate the incident density ratios and identify hyponatremia predictors.</p><p><strong>Results: </strong>A total of 381 patients were included in this study. The total follow-up time was 59 354 pm; the median follow-up time was 164 pm (interquartile range 135-193). There were 259 patients (68%) who never had hyponatremia. Hyponatremia was common in the first 2 months of treatment. Significant factors shown on univariate and multivariate regression analyses were age >50 years, tube feeding alone, advanced nodal metastasis, distant metastasis, carboplatin use, high-grade mucositis, and skin complications.</p><p><strong>Conclusions: </strong>Hyponatremia frequently occurs in the first 2 months of NPC treatment. Advanced age, tube feeding alone, advanced nodal metastasis, distant metastasis, carboplatin use, high-grade mucositis, and skin complications are significantly associated with hyponatremic events.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251377558"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Tracheal Adenoid Cystic Carcinoma with Thyroid Invasion and Mimicking Thyroid Tumors.","authors":"Mustafa Yeşilyurt, Cemile Altınkaya, Sevilay Özmen","doi":"10.1177/01455613251315298","DOIUrl":"10.1177/01455613251315298","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"628-630"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hoarseness as a Presenting Symptom of Ortner's Syndrome: Two Rare Cardiovascular Cases With an Otolaryngology - First Presentation and Literature Review.","authors":"Qidi Hu, Lili Kong, Yi Zhou, Wen Shen, Ru Chen, Jing Deng, Guoqi Sima, Yao Sun","doi":"10.1177/01455613251382348","DOIUrl":"https://doi.org/10.1177/01455613251382348","url":null,"abstract":"<p><p>Ortner's syndrome (cardiac-vocal cord syndrome) is characterized by vocal cord paralysis resulting from underlying cardiovascular conditions. It is typically caused by compression of the left recurrent laryngeal nerve by the pulmonary artery or left atrium, as it passes between the pulmonary artery and aortic arch, leading to left vocal cord paralysis and hoarseness. We report 2 rare cases of hoarseness ultimately diagnosed as Ortner's syndrome (ages 54 and 71). The first case involved a bicuspid aortic valve with an ascending aortic aneurysm, with a clinical course lasting over 10 years due to the rarity of the condition. The second case involved an aortic pseudoaneurysm. Both patients had resolution of hoarseness and coughing postoperatively. These cases emphasize the importance of considering rare, life-threatening cardiovascular causes in the differential diagnosis of hoarseness, highlighting the need for early diagnosis and intervention.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613251382348"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embryonal Rhabdomyosarcoma Arising From the Buccal Mucosa in a Child: Imaging Findings.","authors":"Mustafa Yeşilyurt, Cemile Altınkaya","doi":"10.1177/01455613251321598","DOIUrl":"10.1177/01455613251321598","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP643-NP646"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical Therapies for Management of Olfactory Dysfunction in Chronic Rhinosinusitis with Nasal Polyps: Steroid-Eluting Stents.","authors":"Zhidi Zhang, Qiang Zuo, Yali Du, Hailing Jiang, Jiayue Wang, Furong Ma, Yinghong Zhang","doi":"10.1177/01455613241299640","DOIUrl":"10.1177/01455613241299640","url":null,"abstract":"<p><strong>Objectives: </strong>Steroid-eluting stent implantation after endoscopic sinus surgery (ESS) effectively alleviates postoperative symptoms and polyp recurrence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). However, the efficacy of steroid-eluting stents for the treatment of olfactory dysfunction in CRSwNP and the influencing factors therein have not been studied.</p><p><strong>Methods: </strong>Fifty-nine patients with CRSwNP with olfactory dysfunction from Peking University Third Hospital who were hospitalized for ESS were recruited and randomly divided into a stent group (n = 30) and a control group (n = 29), and were assessed for symptom scores, olfactory function, endoscopic findings, and type 2 inflammatory mediators (IL-4, IL-5, IL-13, IL-33, eotaxin-3, periostin) expression.</p><p><strong>Results: </strong>Postoperative olfactory Visual Analogue Scale (VAS) scores, T&T olfactometer scores, SNOT-22 scores, and Lund-Kennedy (LK) scores were reduced in patients with CRSwNP (<i>P</i> < .01). Postoperative olfactory VAS scores, T&T olfactometer scores, SNOT-22 scores, and LK scores, IL-5, IL-13, and periostin were significantly lower in the stent group than in the control group (<i>P</i> < .05). Correlation analysis was performed and found that the postoperative olfactory VAS scores were strongly correlated with IL-5 and IL-13 (<i>r</i> = .496, <i>P</i> < .001 and <i>r</i> = .289, <i>P</i> = .026), and the postoperative T&T olfactometer scores were strongly correlated with IL-5 and IL-13 (<i>r</i> = .553, <i>P</i> < .001 and <i>r</i> = .398, <i>P</i> = .002).</p><p><strong>Conclusions: </strong>Steroid-eluting stent implantation after ESS is an effective treatment for olfactory deficits in patients with CRSwNP and may be related to the stent's more effective reduction of local type 2 inflammatory mediators in the nasal cavity.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP675-NP684"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic Use Can be De-escalated During Transoral Endoscopic Thyroidectomy: A Bacterial Culture-Based Study.","authors":"Bingbing Wu, Xiao Chen, Junwei Huang","doi":"10.1177/01455613251323040","DOIUrl":"10.1177/01455613251323040","url":null,"abstract":"<p><p><b>Objective:</b> To explore the possibility of reducing the use of antibiotics after transoral endoscopic thyroidectomy vestibular approach (TOETVA). <b>Method:</b> A retrospective study was conducted on patients with thyroid tumors who were diagnosed and underwent surgical treatment at our hospital from 2022 to 2024. Patients diagnosed with T1-stage differentiated thyroid cancer or a benign retrosternal goiter <4 cm with cosmetic needs were included in the current study. Drainage fluid was cultured on the first postoperative day. The differences in infection rates, bacterial culture results, and antibiotic use between patients with clean incisions and those with clean-contaminated incisions were compared. <b>Results:</b> There were no signs of infection in the postoperative drainage fluid or delayed healing due to surgical cavity infection. There was no significant difference in the incidence of postoperative infection or the results of bacterial culture between clean and clean-contaminated incisions or between the groups with and without antibiotic use for clean-contaminated incisions. The proportion of pathogenic bacteria in clean-contaminated incisions was significantly greater than that in clean incisions, while bacteria cultured in clean incisions were mostly common colonizing bacteria. <b>Conclusion:</b> Pathogenic bacteria may indeed exist in the operative cavity of the TOETVA regardless of whether antibiotics are used during the perioperative period. With adequate drainage, the absence of the routine administration of antibiotics or only preventive antibiotics during the perioperative period does not increase the infection rate.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP669-NP674"},"PeriodicalIF":0.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}