{"title":"The Unilateral Excessive Length of Superior Cornu of Thyroid Cartilage: A Case Report.","authors":"Wei Wei Li, Zhengcai Lou","doi":"10.1177/01455613241298069","DOIUrl":"https://doi.org/10.1177/01455613241298069","url":null,"abstract":"<p><p>The excessive length of the superior cornu of the thyroid cartilage is extremely rare, and the etiology is unknown. Few reports of this condition exist in the literature. The objective of the present study was to present a rare case of unilateral excessive length of the superior cornu of the thyroid cartilage.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241298069"},"PeriodicalIF":0.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anil Patel, Eunice Im, Jesse Kresak, Erica Olgaard, Jason E Blatt, Brian C Lobo, Nikita Chapurin
{"title":"Olfactory Neuroblastoma With Divergent Differentiation: Contemporary Management of Unusual Pathology and Literature Review.","authors":"Anil Patel, Eunice Im, Jesse Kresak, Erica Olgaard, Jason E Blatt, Brian C Lobo, Nikita Chapurin","doi":"10.1177/01455613241299684","DOIUrl":"https://doi.org/10.1177/01455613241299684","url":null,"abstract":"<p><p>Olfactory neuroblastoma (ON; Esthesioneuroblastoma) is a malignant tumor that arises from the olfactory neuroepithelium. Very rarely, ON can histologically display a biphenotypic pattern, with only 7 cases reported in the literature to date. We describe a case of this poorly understood entity and review the patient's histology, pathology, and treatment. An 85-year-old man presented with endoscopy and imaging findings of a sinonasal mass arising from the olfactory cleft. Biopsy and further pathological review established Hyams grade 3 and Kadish stage C tumor. The patient underwent combined endoscopic and open-approach resection due to the involvement of the nasal bone and subsequent adjuvant radiation therapy. Specimen contained Flexner-Wintersteiner rosettes and stained positive for the neuroendocrine marker synaptophysin consistent with ON. A second, epithelial component pattern of goblet cells and mucin was observed suggesting divergent differentiation. We are the first group to report next-generation sequencing of this tumor, which revealed a pathogenic mutation in PIK3CA and a likely pathogenic variant in RUNX1 (AML1). ON with divergent differentiation is very rare, and more robust studies characterizing molecular drivers and pathology may aid in clinical management.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241299684"},"PeriodicalIF":0.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of Injury Patterns and Management Strategies on Outcomes in Trauma Patients with Epistaxis.","authors":"Ahmad K Alnemare","doi":"10.1177/01455613241298080","DOIUrl":"https://doi.org/10.1177/01455613241298080","url":null,"abstract":"<p><p><b>Background:</b> Epistaxis is a common emergency, particularly in the context of trauma. Understanding patterns and outcomes of epistaxis in a trauma setting can inform treatment strategies and improve patient care. <b>Objectives:</b> To evaluate the demographic characteristics, clinical features, and outcomes of patients treated for epistaxis following trauma. <b>Methods:</b> This retrospective case-control study included 1106 patients from the National Trauma Data Bank diagnosed with trauma-related epistaxis. The clinical outcomes assessed included hospital stay duration, complication rates, and mortality. <b>Results:</b> In comparison with younger patients, older patients were found to undergo operative intervention significantly more frequently (median age, 65 years vs 44 years; <i>P</i> < .001). The prevalence of cardiovascular and psychiatric comorbidities was higher in the operative group (<i>P</i> = .004 and <i>P</i> = .041, respectively). Mortality risk was not found to be independently influenced by epistaxis management approach. <b>Conclusions:</b> In older individuals with comorbid conditions, trauma-related epistaxis is more likely to result in operative intervention and associated complications. Nonetheless, the management of epistaxis does not appear to have a significant impact on mortality risk.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241298080"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tatiana Ferraro, Abdulla K Ahmed, Weston L Niermeyer, Esther Lee, Punam Thakkar, Arjun S Joshi, Robert T Sataloff
{"title":"Racial Disparities in 30 Day Outcomes Following Total Laryngectomy.","authors":"Tatiana Ferraro, Abdulla K Ahmed, Weston L Niermeyer, Esther Lee, Punam Thakkar, Arjun S Joshi, Robert T Sataloff","doi":"10.1177/01455613241298094","DOIUrl":"https://doi.org/10.1177/01455613241298094","url":null,"abstract":"<p><strong>Background: </strong>Despite the growing literature on racial disparities in the utilization of total laryngectomy (TL), and survival following the treatment of laryngeal cancers, there is a paucity of research in TL cohorts evaluating disparities in the immediate postoperative setting.</p><p><strong>Methods: </strong>In a national multi-institutional cohort, TL cases between 2010 and 2021 were identified using relevant Current Procedural Terminology (CPT) codes. Logistic regression analyses investigated the association between race/ethnicity and adverse outcomes within 30 days postoperatively.</p><p><strong>Results: </strong>This study consisted of 1493 patients who underwent TL with or without radical neck dissection. Black patients underwent free flap and pedicled flap reconstruction more frequently than their counterparts (<i>P</i> = .023) and exhibited a 1.532 times higher odds of surgical complications (<i>P</i> < .001).</p><p><strong>Conclusions: </strong>There are increased rates of surgical complications in Black patients undergoing TL. Given the limited oncologic and socioeconomic variables available through National Surgical Quality Improvement Program, future study of disparate postoperative outcomes in this population is recommended.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241298094"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Topical Therapies for Management of Olfactory Dysfunction in Chronic Rhinosinusitis with Nasal Polyps: Steroid-Eluting Stents.","authors":"Zhidi Zhang, Qiang Zuo, Yali Du, Hailing Jiang, Jiayue Wang, Furong Ma, Yinghong Zhang","doi":"10.1177/01455613241299640","DOIUrl":"https://doi.org/10.1177/01455613241299640","url":null,"abstract":"<p><strong>Objectives: </strong>Steroid-eluting stent implantation after endoscopic sinus surgery (ESS) effectively alleviates postoperative symptoms and polyp recurrence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). However, the efficacy of steroid-eluting stents for the treatment of olfactory dysfunction in CRSwNP and the influencing factors therein have not been studied.</p><p><strong>Methods: </strong>Fifty-nine patients with CRSwNP with olfactory dysfunction from Peking University Third Hospital who were hospitalized for ESS were recruited and randomly divided into a stent group (n = 30) and a control group (n = 29), and were assessed for symptom scores, olfactory function, endoscopic findings, and type 2 inflammatory mediators (IL-4, IL-5, IL-13, IL-33, eotaxin-3, periostin) expression.</p><p><strong>Results: </strong>Postoperative olfactory Visual Analogue Scale (VAS) scores, T&T olfactometer scores, SNOT-22 scores, and Lund-Kennedy (LK) scores were reduced in patients with CRSwNP (<i>P</i> < .01). Postoperative olfactory VAS scores, T&T olfactometer scores, SNOT-22 scores, and LK scores, IL-5, IL-13, and periostin were significantly lower in the stent group than in the control group (<i>P</i> < .05). Correlation analysis was performed and found that the postoperative olfactory VAS scores were strongly correlated with IL-5 and IL-13 (<i>r</i> = .496, <i>P</i> < .001 and <i>r</i> = .289, <i>P</i> = .026), and the postoperative T&T olfactometer scores were strongly correlated with IL-5 and IL-13 (<i>r</i> = .553, <i>P</i> < .001 and <i>r</i> = .398, <i>P</i> = .002).</p><p><strong>Conclusions: </strong>Steroid-eluting stent implantation after ESS is an effective treatment for olfactory deficits in patients with CRSwNP and may be related to the stent's more effective reduction of local type 2 inflammatory mediators in the nasal cavity.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241299640"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Influencing the Time to Treatment of Patients with Idiopathic Sudden Sensorineural Hearing Loss.","authors":"Feng Qin, Siquan Guo, Jinbao Guo, Jibing Qiu","doi":"10.1177/01455613241298097","DOIUrl":"https://doi.org/10.1177/01455613241298097","url":null,"abstract":"<p><p><b>Objective:</b> To identify the factors that influence the time to treatment (TT) in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). <b>Method:</b> This study included a total of 324 patients with ISSNHL, who were treated at our department between September 2021 and May 2024. Basic information and audiological indicators of patients were collected, and their relationship with the TT was analyzed. <b>Results:</b> The patients were classified into long-term (TT >7 days, <i>n</i> = 75) and short-term groups (TT ≤7 days, <i>n</i> = 249). A significant difference was observed in sex, type of hearing loss, pretreatment hearing threshold, average improved hearing threshold, linear distance, and effective rate between the 2 groups. <b>Conclusion:</b> The average pretreatment hearing threshold and linear distance are related to the TT, and both of them are independent influencing factors. Patients with mild hearing loss and long linear distance from hospital may have a longer TT.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241298097"},"PeriodicalIF":0.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carson Shin, Jun Yeon Kim, Jee Yeon Lee, Dong Kyu Lee, Hye Ah Joo, Yun Ji Lee, Yeonjoo Choi, Hong Ju Park
{"title":"Speech Perception Ability and Subjective Satisfaction After Upgrade of Speech Processor in Cochlear Implantation.","authors":"Carson Shin, Jun Yeon Kim, Jee Yeon Lee, Dong Kyu Lee, Hye Ah Joo, Yun Ji Lee, Yeonjoo Choi, Hong Ju Park","doi":"10.1177/01455613241272467","DOIUrl":"https://doi.org/10.1177/01455613241272467","url":null,"abstract":"<p><p><b>Objective:</b> Cochlear implant (CI) users face the decision of whether to upgrade to a new sound processor (SP) with technological advances. We wanted to assess the changes of speech perception ability and aided hearing thresholds as well as subjective satisfaction after upgrade to a new SP. <b>Methods:</b> Fifty-five patients who have used CI for 10 years or more and upgraded to a new SP were enrolled. Word recognition scores were assessed before the upgrade and compared to those assessed 1 year after the upgrade to the Nucleus 7 SP. Changes of aided hearing thresholds and C- and T-levels were analyzed. <b>Results:</b> Previous SPs were 3G in 5, Freedom in 40, N5 in 24, and N6 in 6. Speech perception remained relatively unaffected by SP upgrade. The C- and T-levels increased after SP upgrading and the aided thresholds with previous generation SPs were higher than those 1 year after SP upgrading at all frequencies. In questionnaires, subjects felt that there was a definite subjective benefit to upgrading while most (60%) felt no difference regarding the communication in noise. <b>Conclusions:</b> Speech perception remained similar, but there were improved hearing sensitivity and better satisfaction after SP upgrade.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613241272467"},"PeriodicalIF":0.0,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}