Matteo Gelardi, Adriano Chiappinelli, Alessandro Maselli Del Giudice, Michele Cassano
{"title":"Eosinophil-Mast Cell Inflammation in Middle Ear Effusion Associated With Chronic Rhinosinusitis With Nasal Polyps.","authors":"Matteo Gelardi, Adriano Chiappinelli, Alessandro Maselli Del Giudice, Michele Cassano","doi":"10.1177/01455613261483302","DOIUrl":"https://doi.org/10.1177/01455613261483302","url":null,"abstract":"<p><p>Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly associated with type 2 inflammation, although the inflammatory profile may involve both eosinophils and mast cells. Middle ear disease in CRSwNP is usually attributed to Eustachian tube dysfunction, but inflammatory involvement of the middle ear may also occur. We report the cytological evaluation of middle ear effusion from a patient with CRSwNP. May-Grünwald-Giemsa staining revealed eosinophils, mast cells, and extracellular granules consistent with degranulation. The simultaneous presence of these cellular components suggests an active type 2 inflammatory microenvironment rather than a purely mechanical or obstructive effusion. This observation supports the hypothesis that, in selected patients with CRSwNP, middle ear involvement may represent an extension of the sinonasal inflammatory process. Cytological assessment may therefore provide additional information for inflammatory phenotyping of middle ear disease associated with CRSwNP.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613261483302"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149120641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyeok Tae Kweon, Chan Mi Lee, Cha Dong Yeo, Eun Jung Lee
{"title":"A Case of Squamoid Eccrine Ductal Carcinoma of the Auricle Mimicking Perichondritis.","authors":"Hyeok Tae Kweon, Chan Mi Lee, Cha Dong Yeo, Eun Jung Lee","doi":"10.1177/01455613241234235","DOIUrl":"10.1177/01455613241234235","url":null,"abstract":"<p><p>The subtype of eccrine carcinoma known as squamoid eccrine ductal carcinoma (SEDC) is rare; only 38 cases, including only 6 cases in the ear, have been documented in the literature. This may be the first case to focus on the fact that SEDC, located within the dermal and subcutaneous layers, spares the epidermis histopathologically, which can cause clinicians to confuse SEDC with acute perichondritis.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP766-NP771"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myxoid Liposarcoma of the Parotid Gland.","authors":"Sameh Mezri, Chaima Zitouni, Wadii Thabet, Chaima Ben Amar, Karima Tlili, Fethi Bougrine, Khemaies Akari","doi":"10.1177/01455613241235499","DOIUrl":"10.1177/01455613241235499","url":null,"abstract":"<p><p>Liposarcoma is extremely rare in the parotid gland. In this article, we report the case of an 87-year-old man who presented to our department with swelling in the left parotid region. Magnetic resonance imaging (MRI) revealed a tumor in the superficial lobe of the parotid gland. Total parotidectomy and ipsilateral lymph node dissection were performed. Histologic examination confirmed the diagnosis of myxoid liposarcoma of the parotid gland. On imaging, there was no evidence of nodal or distant metastasis. Radiation therapy was planned, but the patient refused to receive treatment. After a follow-up of 3 years, MRI showed no sign of tumor recurrence and the patient remained symptom-free. The case is original by the tumor's location. Only 8 cases of primary parotid liposarcoma have been reported in the literature. The purpose of this article was to discuss, through our case, clinical and anatomopathological features of parotid gland liposarcomas as well as its treatment options and prognosis.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP757-NP761"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparative Study of Hearing Handicap Inventory and Pure-Tone Audiometry Scores in Unilateral Hearing Impaired Patients.","authors":"XiaoLin Bao, YiLi Ding, Yuan Wang, XiaoWen Liu, BaiCheng Xu, YuFen Guo","doi":"10.1177/01455613241235501","DOIUrl":"10.1177/01455613241235501","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the consistency between the hearing handicap inventory (HHI) and pure-tone audiometry (PTA) scores in assessing hearing status to provide valuable insights for clinical application. <b>Methods:</b> Retrospective analysis of clinical data and the HHI reporting status of 6540 patients admitted between April 2020 and July 2022 for self-reported unilateral hearing loss who met the study inclusion and exclusion criteria. The kappa coefficient was used to evaluate the consistency of HHI and PTA in assessing the hearing status of the participants. <b>Results:</b> The PTA results showed that among the 6540 participants, 3895 exhibited normal hearing, 1434 showed mild hearing loss, 809 presented with moderate hearing loss, and 402 showed severe hearing loss. The mean hearing thresholds from 0.5 to 4 kHz in healthy ears ranged from 3.65 to 18.45 dB HL, with a mean of 10.83 ± 5.29 dB HL; in ears affected by hearing loss, this ranged from 35 to 125 dB HL, with a mean of 69.63 ± 28.45 dB HL. The HHI scores showed that 4820 people had normal hearing, 1245 had mild-to-moderate hearing loss, and 475 had severe hearing loss. The kappa coefficients of normal, mild-to-moderate, and severe hearing loss were 0.312, 0.223, and 0.716, respectively (<i>P</i> = .001). The consistency between the 2 groups was particularly significant in the assessment of severe hearing loss. Using the PTA results as a benchmark, the sensitivity, specificity, positive predictive value, and negative predictive value of the HHI were found to be 73.08%, 87.83%, 95.60%, and 70.98%, respectively. <b>Conclusion:</b> The HHI and PTA results were consistent in the assessment of hearing status, particularly in the assessment of severe hearing loss, and the level of consistency between the 2 methods was high. The combined use of these tools can facilitate a comprehensive assessment of the auditory status of patients with hearing loss.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP813-NP818"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rare Migrated Fishbone Foreign Body in the Nasopharynx.","authors":"Changqing Wang, Min Wang","doi":"10.1177/01455613261496323","DOIUrl":"https://doi.org/10.1177/01455613261496323","url":null,"abstract":"<p><p>Although impaction of the pharyngoesophageal fishbone represents a common otolaryngological emergency, migration of an ingested fish bone into the nasopharynx is an extremely rare clinical occurrence. We present a 57-year-old woman who developed acute odynophagia one hour after fish ingestion, accompanied by a single choking episode, in the absence of nausea or vomiting. The oropharyngeal examination at the bedside failed to identify any foreign body. Given the patient's refusal to computed tomography (CT), she was discharged for outpatient surveillance. Twenty-four hours later, she returned with persistent refractory pharyngeal pain. Repeated pharyngeal endoscopy revealed neither foreign material nor mucosal injury. Multiplanar coronal CT reconstruction identified a 2.63 cm linear hyperattenuating bone fragment within the nasopharyngeal cavity. After topical nasal decongestion, flexible fiberoptic nasopharyngoscopy confirmed a partially embedded migrated fish bone, which was successfully retrieved endoscopically using alligator grasping forceps. Odynophagia resolved immediately after extraction and the patient remained asymptomatic throughout the 2 week follow-up. For patients with persistent pharyngeal pain and high clinical suspicion of retained foreign bodies despite negative physical examination and endoscopic findings, CT should be considered the first-line cross-sectional modality to prevent missed.diagnoses and life-threatening cervicofacial septic complications.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"1455613261496323"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149120649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathogenic Potential of <i>Turicella otitidis</i> and <i>Staphylococcus auricularis</i>: A Case Report.","authors":"Madeline M Marker, Janet S Choi, Tina C Huang","doi":"10.1177/01455613241230245","DOIUrl":"10.1177/01455613241230245","url":null,"abstract":"<p><p><b>Objective:</b> <i>Turicella otitidis</i> and <i>Staphylococcus auricularis</i> have been considered normal aural flora. Their significance in active infection is controversial. We examined a series of patients presenting with acute and chronic otitis media whose ear canal culture isolated <i>T. otitidis</i> and <i>S. auricularis</i> and explored possible pathogenicity, associated factors, and outcomes. <b>Methods:</b> This is a retrospective chart review of patients who presented to a tertiary center outpatient clinic between 2017 and 2022 with otologic microscopic examination of active infection and ear canal culture isolating <i>T. otitidis</i> or <i>S. auricularis</i> only. Clinical course was collected including history, microscopic otoscopy findings, interventions given, outcomes, and sensitivity results. <b>Results:</b> A total of 13 patients (10 with <i>T. otitidis</i> and 3 with <i>S. auricularis</i>) were included. Majority of the patients had a history of otologic surgery (92%) and tympanic membrane perforation (62%). All were treated with combinations of antibiotic otic drops (ie, fluoroquinolone, sulfa, or aminoglycoside based) ± oral antibiotics (ie, penicillin or trimethoprim/sulfamethoxazole). Otorrhea resolved among majority of patients. Otorrhea and mucosalization returned or continued among 4 patients. Sensitivity results demonstrated that 2 of 3 strains of <i>T. otitidis</i> were resistant to clindamycin. There was no resistance against <i>S. auricularis</i> for tested antibiotics. <b>Conclusions:</b> Our findings suggest the potential pathogenicity of <i>T. otitidis</i> and <i>S. auricularis</i>, especially among patients with prior ear surgery and tympanic membrane perforation. Violation of the epithelial barrier from surgery or trauma may contribute to their pathogenicity. Future study is warranted to elucidate pathogenicity of normal aural flora and its mechanisms.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP772-NP779"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Affecting Visual-Only Speech Recognition in Individuals With Cochlear Implants.","authors":"Zhikai Zhang, Chaogang Wei, Keli Cao, Yuhe Liu","doi":"10.1177/01455613241234821","DOIUrl":"10.1177/01455613241234821","url":null,"abstract":"<p><p><b>Objectives:</b> Several reports have underlined the benefits of speechreading (visual-only speech recognition) on speech recognition in individuals with hearing loss after cochlear implantation (CI). However, the factors that would affect the ability of speechreading are unclear. The aim of the present study is to assess the factors that affect speechreading abilities in CI users. <b>Methods:</b> A total of 104 participants were enrolled in this retrospective study. They viewed silent videos of sentences being spoken by a model and were tasked with repeating what they thought had been said. They were tested under audio-only and visual-only conditions. Factors (such as the age, the age of CI; <3 years old vs 3-8 years old; male vs female, etc) believed to affect speechreading abilities were analyzed. <b>Results:</b> The age range of the participants is 8 to 34 years. CI users showed significantly different speechreading abilities among themselves. The authors found that age and hearing loss at 3 to 8 years of age were positively related to superior speechreading recognition scores. <b>Conclusions:</b> CI users followed a more complex method of perceptual compensation. Those who have suffered hearing loss between 3 and 8 years of age are more sensitive to developing an advantage in speech recognition by using speechreading. Older age positively affects speechreading abilities; thus, the more experience CI has, the greater speechreading ability they may exhibit.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP780-NP788"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139975085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of Biologic Graft in Nasal Septal Perforation Repair.","authors":"Jianjun Jing, Liang Li, Yongxiang Wu, Liang Zheng, Longfang Zhang, Haihong Li, Hui Wang","doi":"10.1177/01455613241233748","DOIUrl":"10.1177/01455613241233748","url":null,"abstract":"<p><p><b>Objective:</b> To explore the clinical outcome when biomaterials are used to repair nasal septal perforations. <b>Methods:</b> A total of 12 patients were treated. The nasal septum was dissected via endoscopic approach. A 4 cm × 7 cm biologic graft (Biodesign<sup>®</sup> Tissue Graft) was folded to form a double layer, was placed over the perforation, and was affixed into place using suture. <b>Results:</b> Follow-up ranged from 2 to 8 months after the operation. One patient was not completely healed and presented with a remaining defect of about 2 mm × 8 mm in the upper part of the nasal septum. The remaining 11 patients healed completely. <b>Conclusion:</b> Using a biologic graft to repair nasal septal perforations is an easy operation as it prevents the need to take autologous tissue from the patient, allows for a repair to be performed without creating septal flaps, and has good histocompatibility. It is a safe and effective method that can be used clinically.</p>","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"NP789-NP797"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139975119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mastoidectomy Before the Mastoid Drill.","authors":"Megan A Noonan, Glenn Isaacson","doi":"10.1177/01455613241256427","DOIUrl":"10.1177/01455613241256427","url":null,"abstract":"","PeriodicalId":93984,"journal":{"name":"Ear, nose, & throat journal","volume":" ","pages":"595-597"},"PeriodicalIF":0.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}